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2024-04-26 14:49:33, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_003276               3690 bp    mRNA    linear   PRI 07-JUL-2013
DEFINITION  Homo sapiens thymopoietin (TMPO), transcript variant 1, mRNA.
ACCESSION   NM_003276
VERSION     NM_003276.2  GI:296434313
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3690)
  AUTHORS   Ward,M.C., van der Watt,P.J., Tzoneva,G. and Leaner,V.D.
  TITLE     Deregulated LAP2alpha expression in cervical cancer associates with
            aberrant E2F and p53 activities
  JOURNAL   IUBMB Life 63 (11), 1018-1026 (2011)
   PUBMED   21990273
  REMARK    GeneRIF: this study provides evidence for elevated LAP2alpha
            expression in cervical cancer and suggests that E2F and p53
            activities associate with the positive and negative regulation of
            LAP2alpha expression, respectively
REFERENCE   2  (bases 1 to 3690)
  AUTHORS   Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B,
            Yusuf S, Gerstein HC, Engert JC and Anand S.
  CONSRTM   DREAM investigators
  TITLE     Variation at the NFATC2 locus increases the risk of
            thiazolidinedione-induced edema in the Diabetes REduction
            Assessment with ramipril and rosiglitazone Medication (DREAM) study
  JOURNAL   Diabetes Care 33 (10), 2250-2253 (2010)
   PUBMED   20628086
  REMARK    GeneRIF: Observational study of gene-disease association,
            gene-environment interaction, and pharmacogenomic / toxicogenomic.
            (HuGE Navigator)
REFERENCE   3  (bases 1 to 3690)
  AUTHORS   Davila,S., Froeling,F.E., Tan,A., Bonnard,C., Boland,G.J.,
            Snippe,H., Hibberd,M.L. and Seielstad,M.
  TITLE     New genetic associations detected in a host response study to
            hepatitis B vaccine
  JOURNAL   Genes Immun. 11 (3), 232-238 (2010)
   PUBMED   20237496
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   4  (bases 1 to 3690)
  AUTHORS   Craig,D.W., Millis,M.P. and DiStefano,J.K.
  TITLE     Genome-wide SNP genotyping study using pooled DNA to identify
            candidate markers mediating susceptibility to end-stage renal
            disease attributed to Type 1 diabetes
  JOURNAL   Diabet. Med. 26 (11), 1090-1098 (2009)
   PUBMED   19929986
  REMARK    GeneRIF: Observational study and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   5  (bases 1 to 3690)
  AUTHORS   Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt
            TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M,
            Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ,
            Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S,
            Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD,
            Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE
            and Hingorani AD.
  CONSRTM   ASCOT investigators; NORDIL investigators; BRIGHT Consortium
  TITLE     Gene-centric association signals for lipids and apolipoproteins
            identified via the HumanCVD BeadChip
  JOURNAL   Am. J. Hum. Genet. 85 (5), 628-642 (2009)
   PUBMED   19913121
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   6  (bases 1 to 3690)
  AUTHORS   Hara,H., Hayashi,K., Ohta,K., Itoh,N. and Ohta,M.
  TITLE     A new thymopoietin precursor gene from human thymus
  JOURNAL   Biochem. Mol. Biol. Int. 34 (5), 927-933 (1994)
   PUBMED   7703909
REFERENCE   7  (bases 1 to 3690)
  AUTHORS   Harris,C.A., Andryuk,P.J., Cline,S., Chan,H.K., Natarajan,A.,
            Siekierka,J.J. and Goldstein,G.
  TITLE     Three distinct human thymopoietins are derived from alternatively
            spliced mRNAs
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 91 (14), 6283-6287 (1994)
   PUBMED   7517549
REFERENCE   8  (bases 1 to 3690)
  AUTHORS   Heavner,G.A., Audhya,T. and Goldstein,G.
  TITLE     Peptide analogs of thymopentin distinguish distinct thymopoietin
            receptor specificities on two human T cell lines
  JOURNAL   Regul. Pept. 27 (2), 257-262 (1990)
   PUBMED   2158125
REFERENCE   9  (bases 1 to 3690)
  AUTHORS   Fuccello,A., Audhya,T., Talle,M.A. and Goldstein,G.
  TITLE     Immunoassay for bovine serum thymopoietin: discrimination from
            splenin by monoclonal antibodies
  JOURNAL   Arch. Biochem. Biophys. 228 (1), 292-298 (1984)
   PUBMED   6364989
REFERENCE   10 (bases 1 to 3690)
  AUTHORS   Twomey,J.J., Goldstein,G., Lewis,V.M., Bealmear,P.M. and Good,R.A.
  TITLE     Bioassay determinations of thymopoietin and thymic hormone levels
            in human plasma
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 74 (6), 2541-2545 (1977)
   PUBMED   302007
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DB239672.1, U09086.1,
            BP423544.1, BU932961.1 and BM991833.1.
            This sequence is a reference standard in the RefSeqGene project.
            On May 21, 2010 this sequence version replaced gi:4507554.
            
            Summary: The protein encoded by this gene resides in the nucleus
            and may play a role in the assembly of the nuclear lamina, and thus
            help maintain the structural organization of the nuclear envelope.
            It may function as a receptor for the attachment of lamin filaments
            to the inner nuclear membrane. Mutations in this gene are
            associated with dilated cardiomyopathy. Alternatively spliced
            transcript variants encoding different isoforms have been noted for
            this gene. [provided by RefSeq, May 2010].
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (alpha).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U09086.1, AK315221.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025083 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-593               DB239672.1         1-593
            594-2581            U09086.1           503-2490
            2582-2894           BP423544.1         229-541
            2895-3185           BU932961.1         295-585
            3186-3690           BM991833.1         1-505               c
FEATURES             Location/Qualifiers
     source          1..3690
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q22"
     gene            1..3690
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /note="thymopoietin"
                     /db_xref="GeneID:7112"
                     /db_xref="HGNC:11875"
                     /db_xref="HPRD:01777"
                     /db_xref="MIM:188380"
     exon            1..574
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /inference="alignment:Splign:1.39.8"
     variation       125
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:186697764"
     misc_feature    194..196
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /note="upstream in-frame stop codon"
     variation       244
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370309699"
     variation       283
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374345638"
     variation       285
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:377404642"
     variation       294
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:144959639"
     CDS             296..2380
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /note="isoform alpha is encoded by transcript variant 1;
                     LEM domain containing 4; lamina-associated polypeptide 2;
                     TP beta/gamma; TP alpha; thymopoietin-related peptide
                     isoform alpha; thymopoietin-related peptide isoforms
                     beta/gamma"
                     /codon_start=1
                     /product="thymopoietin isoform alpha"
                     /protein_id="NP_003267.1"
                     /db_xref="GI:4507555"
                     /db_xref="CCDS:CCDS9064.1"
                     /db_xref="GeneID:7112"
                     /db_xref="HGNC:11875"
                     /db_xref="HPRD:01777"
                     /db_xref="MIM:188380"
                     /translation="
MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSKGPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDLLDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDSDRYSDNEEGKKKEHKKVKSTRDIVPFSELGTTPSGGGFFQGISFPEISTRPPLGSTELQAAKKVHTSKGDLPREPLVATNLPGRGQLQKLASERNLFISCKSSHDRCLEKSSSSSSQPEHSAMLVSTAASPSLIKETTTGYYKDIVENICGREKSGIQPLCPERSHISDQSPLSSKRKALEESESSQLISPPLAQAIRDYVNSLLVQGGVGSLPGTSNSMPPLDVENIQKRIDQSKFQETEFLSPPRKVPRLSEKSVEERDSGSFVAFQNIPGSELMSSFAKTVVSHSLTTLGLEVAKQSQHDKIDASELSFPFHESILKVIEEEWQQVDRQLPSLACKYPVSSREATQILSVPKVDDEILGFISEATPLGGIQAASTESCNQQLDLALCRAYEAAASALQIATHTAFVAKAMQADISQAAQILSSDPSRTHQALGILSKTYDAASYICEAAFDEVKMAAHTMGNATVGRRYLWLKDCKINLASKNKLASTPFKGGTLFGGEVCKVIKKRGNKH
"
     misc_feature    299..445
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /note="Thymopoietin protein; Region: Thymopoietin;
                     pfam08198"
                     /db_xref="CDD:149323"
     misc_feature    440..619
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (P42166.2);
                     Region: Linker"
     misc_feature    464..466
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphothreonine; propagated from
                     UniProtKB/Swiss-Prot (P42166.2); phosphorylation site"
     misc_feature    470..472
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P42166.2); phosphorylation site"
     misc_feature    491..493
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P42166.2); phosphorylation site"
     misc_feature    491..493
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    491..493
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    494..496
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P42166.2); phosphorylation site"
     misc_feature    494..496
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    515..517
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphothreonine; propagated from
                     UniProtKB/Swiss-Prot (P42166.2); phosphorylation site"
     misc_feature    515..517
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    530..532
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P42166.2); phosphorylation site"
     misc_feature    530..532
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    623..>709
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /note="LEM domain; Region: LEM; pfam03020"
                     /db_xref="CDD:145916"
     misc_feature    755..757
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphothreonine; propagated from
                     UniProtKB/Swiss-Prot (P42166.2); phosphorylation site"
     misc_feature    755..757
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    761..763
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P42166.2); phosphorylation site"
     misc_feature    761..763
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    767..769
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    770..772
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    773..775
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphothreonine; propagated from
                     UniProtKB/Swiss-Prot (P42166.2); phosphorylation site"
     misc_feature    773..775
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    785..787
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphothreonine; propagated from
                     UniProtKB/Swiss-Prot (P42166.2); phosphorylation site"
     misc_feature    785..787
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    797..799
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    845..847
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P42166.2); phosphorylation site"
     misc_feature    845..847
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    863..883
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (P42166.2);
                     Region: Nuclear localization signal (Potential)"
     misc_feature    1346..1348
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P42166.2); phosphorylation site"
     misc_feature    1346..1348
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    1355..1357
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P42166.2); phosphorylation site"
     misc_feature    1403..1405
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P42166.2); phosphorylation site"
     misc_feature    1565..1567
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (P42166.2); phosphorylation site"
     misc_feature    1676..2377
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /note="Lamina-associated polypeptide 2 alpha; Region:
                     LAP2alpha; pfam11560"
                     /db_xref="CDD:151996"
     misc_feature    2261..2263
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-acetyllysine; propagated from
                     UniProtKB/Swiss-Prot (P42166.2); acetylation site"
     variation       308
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149067616"
     variation       322
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:190115355"
     variation       367
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201960762"
     variation       379
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199549942"
     variation       382
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:114074541"
     variation       409
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200619128"
     variation       411
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374578351"
     variation       421
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372903897"
     variation       423
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371427406"
     variation       455
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376363219"
     variation       456..457
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="cc"
                     /replace="g"
                     /db_xref="dbSNP:368465288"
     variation       520
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:59027673"
     variation       526
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139576816"
     variation       560
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200177466"
     exon            575..701
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /inference="alignment:Splign:1.39.8"
     variation       626
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201838047"
     variation       645
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141387097"
     variation       650
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:113967157"
     variation       653
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200420073"
     variation       665
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375619307"
     variation       676
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370093524"
     variation       677
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200943582"
     exon            702..860
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /inference="alignment:Splign:1.39.8"
     variation       771
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183244086"
     variation       792
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:147012167"
     variation       829
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200016687"
     variation       852
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200923649"
     exon            861..3672
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /inference="alignment:Splign:1.39.8"
     variation       875
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138259721"
     variation       933
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138938727"
     variation       963
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201119852"
     variation       979
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188308994"
     variation       981
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138790561"
     variation       1008
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:35998138"
     variation       1013
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375903462"
     variation       1041
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:191275106"
     variation       1044
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:370585407"
     variation       1062
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:146364154"
     variation       1089
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368211058"
     variation       1108
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369897433"
     variation       1116
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139700737"
     variation       1122
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144465114"
     variation       1149
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146158243"
     variation       1172
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:35645287"
     variation       1174
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370939324"
     variation       1177
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375249647"
     variation       1180
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:142500409"
     variation       1181
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201730568"
     variation       1193
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376074187"
     variation       1204
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369208265"
     STS             1210..2199
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /standard_name="Tmpo"
                     /db_xref="UniSTS:507284"
     variation       1220
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:114939776"
     variation       1232
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139512723"
     variation       1237
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185083543"
     variation       1245
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:35969221"
     variation       1259
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377711296"
     variation       1285
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371441559"
     variation       1289
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:57670957"
     STS             1339..1478
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /standard_name="PMC310794P39"
                     /db_xref="UniSTS:272729"
     variation       1343
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200124801"
     variation       1344
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202106275"
     variation       1345
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147812883"
     variation       1348
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375628010"
     variation       1369
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141347778"
     variation       1407
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:199943517"
     variation       1443
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202166461"
     variation       1460
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:147002330"
     variation       1492
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147635314"
     variation       1509
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149120802"
     variation       1517
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143232629"
     variation       1538
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200367787"
     variation       1541
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11838270"
     variation       1551
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370366685"
     variation       1572
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141443652"
     variation       1576
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377277295"
     variation       1585
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374855899"
     variation       1600
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:181830203"
     variation       1604
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145703021"
     variation       1624
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:138388686"
     variation       1626
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:142981381"
     variation       1653
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368161386"
     variation       1657
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371731646"
     variation       1686
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146132228"
     variation       1693
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143185150"
     variation       1700
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:373861992"
     variation       1724
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34301677"
     variation       1729
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:35761089"
     variation       1766
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:80325832"
     variation       1783
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372248802"
     variation       1834
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:143845319"
     variation       1873
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375056835"
     variation       1886
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199979773"
     variation       1905
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200717863"
     variation       1927
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:12316677"
     variation       1955
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144269053"
     variation       1969
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:151318988"
     variation       1986..1987
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:34406338"
     variation       2004
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147803339"
     variation       2025
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34150443"
     variation       2026
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200856956"
     variation       2072
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369840957"
     variation       2090
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:17459334"
     variation       2097
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376075320"
     variation       2100
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34983516"
     STS             2103..2754
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /standard_name="TMPO_3873"
                     /db_xref="UniSTS:462590"
     variation       2117
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:140881399"
     variation       2123
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369379490"
     variation       2124
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150445385"
     variation       2129
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201929673"
     variation       2136
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367769644"
     variation       2137
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373227285"
     variation       2173
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377465206"
     variation       2226
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369785592"
     variation       2244
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138295270"
     variation       2252
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202035749"
     variation       2263
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201034441"
     variation       2315
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200419485"
     variation       2363
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:17028450"
     variation       2380
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145677259"
     variation       2406
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371325939"
     variation       2434
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372009555"
     variation       2537
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:113105753"
     variation       2566
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139018373"
     variation       2620
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:114931887"
     variation       2634
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2043923"
     variation       2661
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189841238"
     variation       2712
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:75569613"
     variation       2717
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:79909726"
     variation       2736
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:75460359"
     variation       2750
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:17028453"
     variation       2789
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:369534215"
     variation       2826
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:181477122"
     variation       2853
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185280612"
     variation       2865
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:377237104"
     variation       2904
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:79502085"
     variation       2906
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11109520"
     variation       2928
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373459649"
     variation       3161
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:376889618"
     variation       3355..3360
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace=""
                     /replace="ctgtat"
                     /db_xref="dbSNP:371536928"
     variation       3365
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141356917"
     variation       3374
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:17028456"
     STS             3462..3611
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /standard_name="STS-T25858"
                     /db_xref="UniSTS:194"
     STS             3464..3657
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /standard_name="STS-T25858"
                     /db_xref="UniSTS:7104"
     STS             3480..3649
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /standard_name="RH47529"
                     /db_xref="UniSTS:21038"
     variation       3493
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189746139"
     variation       3552
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150771350"
     polyA_signal    3647..3652
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
     polyA_site      3672
                     /gene="TMPO"
                     /gene_synonym="CMD1T; LAP2; LEMD4; PRO0868; TP"
ORIGIN      
gttcttggggcgtgggcgaagcaggctgctcgcctcctgcctgtagtgtgtgggctggggttggtgcgagcttccagcttggccgcagttggttcgtagttcggctctggggtcttttgtgtccgggtctggcttggctttgtgtccgcgagtttttgttccgctccgcagcgctcttcccgggcaggagccgtgaggctcggaggcggcagcgcggtccccggccaggagcaagcgcgccggcgtgagcggcggcggcaaaggctgtggggagggggcttcgcagatccccgagatgccggagttcctggaagacccctcggtcctgacaaaagacaagttgaagagtgagttggtcgccaacaatgtgacgctgccggccggggagcagcgcaaagacgtgtacgtccagctctacctgcagcacctcacggctcgcaaccggccgccgctccccgccggcaccaacagcaaggggcccccggacttctccagtgacgaagagcgcgagcccaccccggtcctcggctctggggccgccgccgcgggccggagccgagcagccgtcggcaggaaagccacaaaaaaaactgataaacccagacaagaagataaagatgatctagatgtaacagagctcactaatgaagatcttttggatcagcttgtgaaatacggagtgaatcctggtcctattgtgggaacaaccaggaagctatatgagaaaaagcttttgaaactgagggaacaaggaacagaatcaagatcttctactcctctgccaacaatttcttcttcagcagaaaatacaaggcagaatggaagtaatgattctgacagatacagtgacaatgaagaaggaaagaagaaagaacacaagaaagtgaagtccactagggatattgttcctttttctgaacttggaactactccctctggtggtggattttttcagggtatttcttttcctgaaatctccacccgtcctcctttgggcagtaccgaactacaggcagctaagaaagtacatacttctaagggagacctacctagggagcctcttgttgccacaaacttgcctggcaggggacagttgcagaagttagcctctgaaaggaatttgtttatttcatgcaagtctagccatgataggtgtttagagaaaagttcttcgtcatcttctcagcctgaacacagtgccatgttggtctctactgcagcttctccttcactgattaaagaaaccaccactggttactataaagacatagtagaaaatatttgcggtagagagaaaagtggaattcaaccattatgtcctgagaggtcccatatttcagatcaatcgcctctctccagtaaaaggaaagcactagaagagtctgagagctcacaactaatttctccgccacttgcccaggcaatcagagattatgtcaattctctgttggtccagggtggggtaggtagtttgcctggaacttctaactctatgcccccactggatgtagaaaacatacagaagagaattgatcagtctaagtttcaagaaactgaattcctgtctcctccaagaaaagtccctagactgagtgagaagtcagtggaggaaagggattcaggttcctttgtggcatttcagaacatacctggatccgaactgatgtcttcttttgccaaaactgttgtctctcattcactcactaccttaggtctagaagtggctaagcaatcacagcatgataaaatagatgcctcagaactatcttttcccttccatgaatctattttaaaagtaattgaagaagaatggcagcaagttgacaggcagctgccttcactggcatgcaaatatccagtttcttccagggaggcaacacagatattatcagttccaaaagtagatgatgaaatcctagggtttatttctgaagccactccactaggaggtattcaagcagcctccactgagtcttgcaatcagcagttggacttagcactctgtagagcatatgaagctgcagcatcagcattgcagattgcaactcacactgcctttgtagctaaggctatgcaggcagacattagtcaagctgcacagattcttagctcagatcctagtcgtacccaccaagcgcttgggattctgagcaaaacatatgatgcagcctcatatatttgtgaagctgcatttgatgaagtgaagatggctgcccataccatgggaaatgccactgtaggtcgtcgatacctctggctgaaggattgcaaaattaatttagcttctaagaataagctggcttccactccctttaaaggtggaacattatttggaggagaagtatgcaaagtaattaaaaagcgtggaaataaacactagtaaaattaaggacaaaaagacatctatcttatctttcaggtactttatgccaacattttcttttctgttaaggttgttttagtttccagatagggctaattacaaaatgttaagcttctacccatcaaattacagtataaaagtaattgcctgtgtagaactacttgtcttttctaaagatttgcgtagataggaagcctggtacaaacaatttaacgctttctagatcacatattagtctctaagttgttttctgtttcctgctttacttatgtttttacaattctccaaaactaagaaaattctaattaggatataaggagtatttactgttcaatagaataatatgcatcctcctttatacctaggacagaattaaacatttgttacacattcagaacagtgatgttgttctttttgatacttttatctcagtatcttttcacgttccataacttgtccatatttttgctcatattttcttacttttctttgttatttattcatgtctgcaacatcaatcatagtagtctagatcaatgcaactcaaagcaccagtctacaaactgttacttatccacaggcaagataagcatgcacaagaatttaaatctagagatactttttaggtcaatgacaggatttgattttttagcaaaattttattaatagctaaagcaatgtattgatttacactctgatgcaagtaatttatctcttcattgactggtagcaaccaattcatggaccagtaccatggaccacactttgagaaacacttctttggataataatagatatcctgggatagtgcatgttcaccatctattttgtcagataatggggccttttaaaaaataatactttgctttcatgatatattgtattttgtggaaagttaagtttagcaatatagactctaaaagcaaattaaatttttttaagccataagaaattatactatatcccagtatctgtatgtctgtataaagcagtgtattatcatgttttcatttctgtgattgtaagttaagagtcttaactgcagaggtattgtggaaagtagtagccttaagcataataaaatatggtctcttgggtactccctctggccattaccacattcttagattatatgtgtccatctttgcagctttctgagagtaattttatttgttgtcttctgaaatgtacatgtatacatgtacctactgagtgctatgtgatttttaaaaatgtattactgtagaatgcttctgcaaattcaataaagttgttaaatttgaacagtgaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:7112 -> Molecular function: GO:0003677 [DNA binding] evidence: IEA
            GeneID:7112 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:7112 -> Molecular function: GO:0005521 [lamin binding] evidence: TAS
            GeneID:7112 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IEA
            GeneID:7112 -> Cellular component: GO:0000785 [chromatin] evidence: IDA
            GeneID:7112 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:7112 -> Cellular component: GO:0005634 [nucleus] evidence: TAS
            GeneID:7112 -> Cellular component: GO:0005635 [nuclear envelope] evidence: TAS
            GeneID:7112 -> Cellular component: GO:0005637 [nuclear inner membrane] evidence: IEA
            GeneID:7112 -> Cellular component: GO:0016021 [integral to membrane] evidence: IEA

by @meso_cacase at DBCLS
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