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2024-04-20 23:11:57, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_002867 12844 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens RAB3B, member RAS oncogene family (RAB3B), mRNA.
ACCESSION NM_002867
VERSION NM_002867.3 GI:296278255
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 12844)
AUTHORS Zhang,W., Shen,Y., Jiao,R., Liu,Y., Deng,L. and Qi,C.
TITLE Crystal structure of inactive form of Rab3B
JOURNAL Biochem. Biophys. Res. Commun. 418 (4), 841-844 (2012)
PUBMED 22321395
REMARK GeneRIF: The structure of Rab3B:GDP complex was solved to 1.9A
resolution and the structural base comparison with other Rab3
members provides a structural basis for the GDP/GTP switch in
controlling the activity of small GTPase.
REFERENCE 2 (bases 1 to 12844)
AUTHORS Piper Hanley,K., Hearn,T., Berry,A., Carvell,M.J., Patch,A.M.,
Williams,L.J., Sugden,S.A., Wilson,D.I., Ellard,S. and Hanley,N.A.
TITLE In vitro expression of NGN3 identifies RAB3B as the predominant
Ras-associated GTP-binding protein 3 family member in human islets
JOURNAL J. Endocrinol. 207 (2), 151-161 (2010)
PUBMED 20807725
REMARK GeneRIF: These results support an important inter-species
difference in regulating insulin exocytosis where RAB3B is the most
expressed isoform in human islets.
REFERENCE 3 (bases 1 to 12844)
AUTHORS Chung,C.Y., Koprich,J.B., Hallett,P.J. and Isacson,O.
TITLE Functional enhancement and protection of dopaminergic terminals by
RAB3B overexpression
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 106 (52), 22474-22479 (2009)
PUBMED 20007772
REMARK GeneRIF: RAB3B improves dopamine handling and storage capacity at
presynaptic terminals, and confers protection to vulnerable DA
neurons.
REFERENCE 4 (bases 1 to 12844)
AUTHORS Zou,L., Zhou,J., Zhang,J., Li,J., Liu,N., Chai,L., Li,N., Liu,T.,
Li,L., Xie,Z., Liu,H., Wan,Y. and Wu,Y.
TITLE The GTPase Rab3b/3c-positive recycling vesicles are involved in
cross-presentation in dendritic cells
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 106 (37), 15801-15806 (2009)
PUBMED 19717423
REMARK GeneRIF: Rab3b/3c-positive recycling vesicles are involved in and
may constitute one of the recycling compartments in exogenous
antigen cross-presentation.
REFERENCE 5 (bases 1 to 12844)
AUTHORS Rotondo,F., Scheithauer,B.W., Kovacs,K. and Bell,D.C.
TITLE Rab3B immunoexpression in human pituitary adenomas
JOURNAL Appl. Immunohistochem. Mol. Morphol. 17 (3), 185-188 (2009)
PUBMED 19384079
REMARK GeneRIF: these results add new information to the view that Rab3B
is involved in the regulation of pituitary hormone secretion.
REFERENCE 6 (bases 1 to 12844)
AUTHORS Regazzi,R., Ravazzola,M., Iezzi,M., Lang,J., Zahraoui,A.,
Andereggen,E., Morel,P., Takai,Y. and Wollheim,C.B.
TITLE Expression, localization and functional role of small GTPases of
the Rab3 family in insulin-secreting cells
JOURNAL J. Cell. Sci. 109 (PT 9), 2265-2273 (1996)
PUBMED 8886977
REFERENCE 7 (bases 1 to 12844)
AUTHORS Weber,E., Jilling,T. and Kirk,K.L.
TITLE Distinct functional properties of Rab3A and Rab3B in PC12
neuroendocrine cells
JOURNAL J. Biol. Chem. 271 (12), 6963-6971 (1996)
PUBMED 8636125
REFERENCE 8 (bases 1 to 12844)
AUTHORS Weber,E., Berta,G., Tousson,A., St John,P., Green,M.W.,
Gopalokrishnan,U., Jilling,T., Sorscher,E.J., Elton,T.S.,
Abrahamson,D.R. et al.
TITLE Expression and polarized targeting of a rab3 isoform in epithelial
cells
JOURNAL J. Cell Biol. 125 (3), 583-594 (1994)
PUBMED 8175882
REFERENCE 9 (bases 1 to 12844)
AUTHORS Rousseau-Merck,M.F., Zahraoui,A., Touchot,N., Tavitian,A. and
Berger,R.
TITLE Chromosome assignment of four RAS-related RAB genes
JOURNAL Hum. Genet. 86 (4), 350-354 (1991)
PUBMED 1999336
REFERENCE 10 (bases 1 to 12844)
AUTHORS Zahraoui,A., Touchot,N., Chardin,P. and Tavitian,A.
TITLE The human Rab genes encode a family of GTP-binding proteins related
to yeast YPT1 and SEC4 products involved in secretion
JOURNAL J. Biol. Chem. 264 (21), 12394-12401 (1989)
PUBMED 2501306
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AU119030.1, BC005035.1 and AL589663.19.
On May 19, 2010 this sequence version replaced gi:19923749.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AU119030.1, BC005035.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025082, ERS025088 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-88 AU119030.1 1-88
89-1640 BC005035.1 1-1552
1641-12844 AL589663.19 77586-88789 c
FEATURES Location/Qualifiers
source 1..12844
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p32-p31"
gene 1..12844
/gene="RAB3B"
/note="RAB3B, member RAS oncogene family"
/db_xref="GeneID:5865"
/db_xref="HGNC:9778"
/db_xref="HPRD:01540"
/db_xref="MIM:179510"
exon 1..213
/gene="RAB3B"
/inference="alignment:Splign:1.39.8"
misc_feature 91..93
/gene="RAB3B"
/note="upstream in-frame stop codon"
CDS 214..873
/gene="RAB3B"
/note="brain antigen RAB3B"
/codon_start=1
/product="ras-related protein Rab-3B"
/protein_id="NP_002858.2"
/db_xref="GI:19923750"
/db_xref="CCDS:CCDS560.1"
/db_xref="GeneID:5865"
/db_xref="HGNC:9778"
/db_xref="HPRD:01540"
/db_xref="MIM:179510"
/translation="
MASVTDGKTGVKDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTEKGQLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSLDTDPSMLGSSKNTRLSDTPPLLQQNCSC
"
misc_feature 268..870
/gene="RAB3B"
/note="GTPase SAR1 and related small G proteins [General
function prediction only]; Region: COG1100"
/db_xref="CDD:31297"
misc_feature 277..771
/gene="RAB3B"
/note="Rab GTPase family 3 contains Rab3A, Rab3B, Rab3C
and Rab3D; Region: Rab3; cd01865"
/db_xref="CDD:206657"
misc_feature order(277..279,376..378,382..390,433..435,439..441,
460..465,472..474,484..486,490..501,586..594,760..762,
769..771)
/gene="RAB3B"
/note="effector interaction site; other site"
/db_xref="CDD:206657"
misc_feature 277..285
/gene="RAB3B"
/note="Rab subfamily motif 1 (RabSF1); other site"
/db_xref="CDD:206657"
misc_feature 298..321
/gene="RAB3B"
/note="G1 box; other site"
/db_xref="CDD:206657"
misc_feature order(304..324,352..357,364..366,370..375,451..453,
616..621,625..630,706..714)
/gene="RAB3B"
/note="GTP/Mg2+ binding site [chemical binding]; other
site"
/db_xref="CDD:206657"
misc_feature order(322..357,364..372)
/gene="RAB3B"
/note="Rab subfamily motif 2 (RabSF2); other site"
/db_xref="CDD:206657"
misc_feature order(352..354,367..393)
/gene="RAB3B"
/note="Switch I region; other site"
/db_xref="CDD:206657"
misc_feature 364..390
/gene="RAB3B"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (P20337.2);
Region: Effector region (By similarity)"
misc_feature order(367..369,379..402,421..423,427..429)
/gene="RAB3B"
/note="putative GEF interaction site [polypeptide
binding]; other site"
/db_xref="CDD:206657"
misc_feature 373..375
/gene="RAB3B"
/note="G2 box; other site"
/db_xref="CDD:206657"
misc_feature order(376..381,385..387,439..444,463..465,469..471,
475..483)
/gene="RAB3B"
/note="putative GDI interaction site [polypeptide
binding]; other site"
/db_xref="CDD:206657"
misc_feature 376..390
/gene="RAB3B"
/note="Rab family motif 1 (RabF1); other site"
/db_xref="CDD:206657"
misc_feature 427..441
/gene="RAB3B"
/note="Rab family motif 2 (RabF2); other site"
/db_xref="CDD:206657"
misc_feature 442..453
/gene="RAB3B"
/note="G3 box; other site"
/db_xref="CDD:206657"
misc_feature order(451..453,457..489)
/gene="RAB3B"
/note="Switch II region; other site"
/db_xref="CDD:206657"
misc_feature 460..477
/gene="RAB3B"
/note="Rab family motif 3 (RabF3); other site"
/db_xref="CDD:206657"
misc_feature 484..498
/gene="RAB3B"
/note="Rab family motif 4 (RabF4); other site"
/db_xref="CDD:206657"
misc_feature 511..528
/gene="RAB3B"
/note="Rab family motif 5 (RabF5); other site"
/db_xref="CDD:206657"
misc_feature 580..609
/gene="RAB3B"
/note="Rab subfamily motif 3 (RabSF3); other site"
/db_xref="CDD:206657"
misc_feature 616..627
/gene="RAB3B"
/note="G4 box; other site"
/db_xref="CDD:206657"
misc_feature 706..714
/gene="RAB3B"
/note="G5 box; other site"
/db_xref="CDD:206657"
misc_feature 754..771
/gene="RAB3B"
/note="Rab subfamily motif 4 (RabSF4); other site"
/db_xref="CDD:206657"
misc_feature 763..765
/gene="RAB3B"
/experiment="experimental evidence, no additional details
recorded"
/note="S-nitrosylation site; modified site"
misc_feature 781..783
/gene="RAB3B"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(P20337.2); phosphorylation site"
exon 214..441
/gene="RAB3B"
/inference="alignment:Splign:1.39.8"
exon 442..560
/gene="RAB3B"
/inference="alignment:Splign:1.39.8"
exon 561..685
/gene="RAB3B"
/inference="alignment:Splign:1.39.8"
variation 654
/gene="RAB3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:2230325"
exon 686..12844
/gene="RAB3B"
/inference="alignment:Splign:1.39.8"
variation 772
/gene="RAB3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:34017695"
variation 779
/gene="RAB3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:35212254"
STS 1540..1642
/gene="RAB3B"
/standard_name="D11S3114"
/db_xref="UniSTS:152207"
STS 1619..1721
/gene="RAB3B"
/standard_name="D8S2278"
/db_xref="UniSTS:473906"
STS 1624..3140
/gene="RAB3B"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
STS 1624..1713
/gene="RAB3B"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
STS 2791..2943
/gene="RAB3B"
/standard_name="RH36067"
/db_xref="UniSTS:81485"
STS 4873..5041
/gene="RAB3B"
/standard_name="D1S1425"
/db_xref="UniSTS:149621"
variation 5664
/gene="RAB3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:2842573"
STS 7097..8649
/gene="RAB3B"
/standard_name="STS-T76997"
/db_xref="UniSTS:57556"
variation 7323
/gene="RAB3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:2842574"
STS 9165..9292
/gene="RAB3B"
/standard_name="SHGC-74822"
/db_xref="UniSTS:9270"
variation 9703
/gene="RAB3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:2244262"
variation 10487
/gene="RAB3B"
/replace="a"
/replace="g"
/db_xref="dbSNP:2244233"
variation 10860
/gene="RAB3B"
/replace="a"
/replace="c"
/db_xref="dbSNP:2495225"
STS 11372..11472
/gene="RAB3B"
/standard_name="SHGC-74815"
/db_xref="UniSTS:2859"
variation 12059
/gene="RAB3B"
/replace=""
/replace="ac"
/replace="c"
/replace="t"
/db_xref="dbSNP:67999231"
variation 12578
/gene="RAB3B"
/replace="g"
/replace="t"
/db_xref="dbSNP:12730"
variation 12609
/gene="RAB3B"
/replace="c"
/replace="t"
/db_xref="dbSNP:1045633"
STS 12685..12828
/gene="RAB3B"
/standard_name="SHGC-36782"
/db_xref="UniSTS:81076"
ORIGIN
agactccgcccttgggcggggcctggatgcggccggagcggagcagtgctggagcgggagcctcagccctcaggcgccactgtgaggacctgaccggaccagaccatcccgcagcgccccgccccggccccctccgcgccctcccgacgccaggtcctgccgtcccgccgaccgtccgggagcgaacccgtcgtcccgcactcggagtccgcgatggcttcagtgacagatggtaaaactggagtcaaagatgcctctgaccagaattttgactacatgtttaaactgcttatcattggcaacagcagtgttggcaagacctccttcctcttccgctatgctgatgacacgttcaccccagccttcgttagcaccgtgggcatcgacttcaaggtgaagacagtctaccgtcacgagaagcgggtgaaactgcagatctgggacacagctgggcaggagcggtaccggaccatcacaacagcctattaccgtggggccatgggcttcattctgatgtatgacatcaccaatgaagagtccttcaatgctgtccaagactgggctactcagatcaagacctactcctgggacaatgcacaagttattctggtggggaacaagtgtgacatggaggaagagagggttgttcccactgagaagggccagctccttgcagagcagcttgggtttgatttctttgaagccagtgcaaaggagaacatcagtgtaaggcaggcctttgagcgcctggtggatgccatttgtgacaagatgtctgattcgctggacacagacccgtcgatgctgggctcctccaagaacacgcgtctctcggacaccccaccgctgctgcagcagaactgctcatgctaggcaaggcccaccttcctgacctcccctcattgtggccccacacccagtctgcttctccctgttacacactgtccgctctcagcccactctccctgttacacactgcccacactcagagcaagatgagttgctgctattctttgcctgcccctggggttctctgcagatggtcccagtaatagatactcagcactagactaacataacaggtcactacacgggtgcagaatcactttacaaaagaagactctgttttacgaaggggattcactacagggacttagagaacagtctcttttctgcctttaaaatgagagttcctccatttaccaaaatttgacacgcacacattcttcaggggcatgccaattgcgtaaagtgaggctcgcctgcatagctaatcctgttaaagacaacttctcaaagcacaacgtgcttgtttcctatcgggctccctgcggggctttctctcactacaagtcaagcttgggctctcaaagccctgcgcctgttaccacggatgcccacagggcctgggcagttgctgtggcgacaggaagagctaatcttcagagagctcagactctctaatgatgctgaaggagcaaaggctgagtcagaaacacacttaagagaaaaggattggccgggcgcggtggctcacgcctgtaatcccagcactttgggaggccgaggcgggtggatcatgaggtcaggagatcgagaccatcctggctaacaaggtgaaaccccgtctctactaaaaatacaaaaaattagccgggcgcggtggcgggcgcctgtagtcccagctactcgggaggctgaggcaggagaatggcgtgaacccgggaagcggagcttgcagtgagccgagattgcgccactgcagtccgcagtccggcctgggcgacagagcgagactccgtctcaaaaaaaaaaaaaaaaaaaaaaagagaaaaggattatcccctacaaaatgtcagaggttcctgctatatgaaagagcaagtaggtatgctcaagaaagacaaacagagaaaaagagaaacaggcaagatcaagaaacagatcatgagtttctgattttgctgctttccagttggttcttaactgtgggaacttagtgaaattggttattagttcttagactcctagaacctgaggattttagatttgacgggatgcccaaatttacctagtctgactagtcagttctaaccttcctttttctgacaagtgactgtcaagcctaacaatcaaatctctttcttttaaagcacaccttctaggcagggacaggagctcattttccacaccatctttgtcaactctcatagaaagttttccttgtatcgagctcaaatctgcctcctggaaattcttcttcttcttccctccctgttggtaccagctctgctgtcagagacttcacagtctgtgctccctctgccctgtgacgtcttcagactatttgagaacaggaatcatgactcctgggacttgccttttctctaggtcaaatacctctataattccatctgctgttcttcatagggtcttctccctatcctgcccttttcctccaatccatcttttaactgctcttgagcagtctaactgagaagtatgattcaaagcaaaataaatcttaaggtggcatgactctgaaaaaattgagaaaattgaactcagagatcccgatcccaacccctttctcctgggagtgaaaccttagtttctaccagagagtgtgggaaaccacttctggtggaagccccttaattaaatacctgaggaaaaaaataaaagaaactcagagaccagaataaattagctcattattctagcttgcttggccacagggacatattttgttttggctgaaataatgacatggaactggcagtgattccagaaaacctttcttctctatcatggcctgaatcctcagccacctcaaaagtcagcgggcaggaggagtctctcgccagttttcttttcatttcaaatgaggctcattgtcctagaaaagtaattaactagcaaccagtccaatgactaaataaaaggaccatccagctgtggctcacacctgtaatcccagcactttggaaagccaaggcaggaggaacacttgaggccaggagtttgagaccagcctgggcaatgtggtcaaattctatccctacaaaaaaaaaaattagccagatgtgatggtgcatgcctgtagtcccagctacttgggaggctgaggcaggaggattgcttgagcccaagaatttgaggttgcagtgagctgtaattatgccactgcattccagtctgggtgacagagtaagaataagaccctgtctctctgtctctctttctctctttttttttttaaaggagtcagctctacaaagatgttgctttctttgatgcaatgcagagagcagagctttggacttggaatcaggagacccggactctgtcattaaatcaactgtgactctgggccagttactttccacttttgagtcttgatttcctacttataaaatgagggagcttatttggatgatctttaaggtctcttttggcactaataactcggtgtctcttttttttcaccttcaccatttcagttgatccaccaaacaaacctgagagatcaggattggcatccaagagttgtctcggccaactctgatgtcatgcttactctgtactagacattgttccaagcattttacgtgcattaactcatttatcttcccaacatcttgtgagggaggcactatagtgagcctcatttgaagatgaggaaacaaaggtacaaagaggttctagctggacctctaaagtcacataataagtaagtggtagagctggagttcacatccaggcagtaggctccaaggtctgtgctcttaaccacattctgggctgcatcttttatagacaaactatgatccagagagattacgagacttggatcacataccaagagagtgttaaagccacattaggattcaattccagggccatcagattccaagtccactggagaaaagatgtatatctctaatctgttaacaaattgctcaactactcagactaatcccaggtgatggatgtctaatgctcaggaaaggcgagtcagtctctgaggcaacagatcccatgggcctgggtagaaaatgcccagtgcttcccagtcccaagtgctggctttccctgtatctgcctctgccaggcaacacttatcaggctcccaatcagcaggagcctccatgctccactttgaacagcctctatgctccagcaatggggcatttgtgaagagtgacttgattaacttttctgaccatgggtataatacagttgcttcagagggcagtggttctgggtgtgatttttacactgtaacattgtatacagtgtcatggataattactatttttttctggtcattaacactcacctactctagtactaggatttcagaccaaggtcctcatgacgcctggatattttagtatctatatccaataatcttttctctcctactgaatatccaggcaaagatgaaatcgttttctttaaaactgtcaaattctgtaaaactcaggagccagttcaagggaacaagcatcttcacaatagatggaatcaagagttaaatgttatagtggcaagcttgtctactgggcaacagacaaccagacctgcttgtgagatggcagctccccagccctgctctgtgacctcatttctgtcaaatgaaaggcagcagcttccagctgattgcagcatagtgttcatcaatcacagtaatagcgcaattagccaccaaggttcaagctgtgtaatatgtgttagtggcaacttgtcctggatttaatcttcctcaacaatccaaataaaatatttaaaaactcttgacttctggctgggcgcagcagctcatgcctgtaatcccagcactttgggaggccgaggtgggcagatcacctgaggtcaggagttcaagaccagcctgggcaacatggtgaaacccccatctctactaaaaatacaaaaattagccaggcgtggtggtgggcacctgaaatccctactcaggaggctgaggcagagaa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ggactgttaagaggctgtgcagcttgggttaagtcattcttatctctgggcttcaggagcttagaccagatagtttctacaggctctcttggtgctgatgccttgggattctgtggctgttttctgtaagatctgcaagggggaaacaggattttggcagcaatcctttcattactaaagcttcctttcttttcgggtacagtgaaaagagccaaggctgtgtgaccccctcatcacttagccaggcgtatggtcctggtttctgaggctgccagaaagcatcttagcaatttgtgtttggatggtccatgcctgactattctaggctggaggttcctaaagagtaacaagaggaagagaaacaagaatctctgacacttgttgagaatagagcacagtcccatttgtttgaaaagagacaccaggcagccatgtttatgtgccagaaatgcattccacctcaaggaggacttaatttatggacccgtgtgtgccaggctgagctgggcaagatctttctcaggacaaactctgccatgcagctaaaagcctggaaactaaaggatttcatgtagtaaactatcttccaacccctgtagacatcagaccacaggatgaggtttcagaaggtcataaggcagaatagttaagcctacagggcttacagtctgacagacctgggttcagttcttgggtcttcatcactagttttgtgacttcgggaagatgactcccggagcctcagtgagcctcagttacttcatatgtaaatgaagtaatactatctacttcacaaggctgttgaaaggattaaatggagaatgggtgtaaaacccttagtgcagtgccgtgcacacacagtagatgccgaacgtgtgatgttggcactacacaatgtgtaatcccaatcaggcagagctaggcaggcaaatctaatccaggatctttgtaaggggactgagaaccagagactggagaaagccagtgtaaacaccatgagcaaaggagcaagagaaggggcattgtgtaagtaggagatggagcttgaacttactaagtggatcagggtagaagaatccagtcaggaccaagggaggagagtccaggaaaatgccatgagcagctctgtagcatgaccttgttgggctgggttaaagtagggtctgccaccagtcatgtgacagaaaggtacctcatgcacttcctccttcccccagaaatcagcctccaggagtgaggaatgagcccagaatgagagtttagagtgctccagagcctttgttagaggtgccctccgacattcagaaaaccaggattccagagacctgggtttgagtcctgactttgcagcatactaactgtgtgatcttgaaccaacatattttcacctaatgaggctgacaatcttccctacttcacaaaatagttatgagagtcaaataaaagtacattttagaaagtgaaatgctgtggacatttaaggtggagccactgtgagagtctagggggatagatggtattcgtctcagaatgaaacgaatacacccctctcagagccctttccaaggatcccctccttctttcagctccttccctccacctcaatacacactcctgtcccaggaacctaacctcatctagaaataccagggccagcatgccttacacctagaggtttggttggcttcagagaaacttctggaggctaaaagcagccaagaagaatcagccactacatgctgggcctggatgaacagagcagtgagctgtgatggggctggggctggggcccaggaggagcaggcaggagagtttgtatgcaccgtgattcaaatattataacaaaaatcatcgatcatgtgttaggcactttacagttcccaaagcactttcccatccatgccctgatgatctttgacacaacactgtgatgtgggttttattatttccagtacagatgaggaagactgaggcctgcatcagtgaagcaacctatccaagactacatagagaaggcagtaaatggcagggttagtctcagaacaggggagggtctgttccccccgcagtgggcagtcctaattctgaacttcacctatctgggggtgatagaggggaacaagaggaagcctgctgaagagaaaacctaaacatctgttttgtctacgtatgacttcctctgcttgtgggagagaaggaaggaaaggaacacattgttgtcagccccacaaccccaacagaattaaaccctggagcaggttgaacagcagaggcttccctcagatcaaggagccaggagcagatgatctatctctgtggccacacagagagatgtcaccttatgcaatttgcatatcatattcaattcccccaactgctctttctaatttattcaactggggaccaggctggtctcatgccaacctaggagatgtaccatagcagtatgagcagaattcctcaggaggaacaattagcaaaaactgcagttgcctctcgataggcctgagcagagagaggaacaatagctctcacgtctctcctcatcagattctaactaagcagatgttctcatgcttttttcttcttcctatgttctgtatactgacacctcttctcagtggcatatgaaatatgaaatgtcatgtgttgtgagtttgtataaatataaaggaatatatatacacagtagcaaaagagaagatctcatttacaaatatctatggtgtttccttgttctgtgttgatctgttttattgatacaaactgaattttcttaatgtatcttctatctctattatagtggcaatgatggtatatgcattaaagttcttctgaattgtg
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:5865 -> Molecular function: GO:0003924 [GTPase activity] evidence: TAS
GeneID:5865 -> Molecular function: GO:0005525 [GTP binding] evidence: IEA
GeneID:5865 -> Biological process: GO:0006184 [GTP catabolic process] evidence: TAS
GeneID:5865 -> Biological process: GO:0007264 [small GTPase mediated signal transduction] evidence: IEA
GeneID:5865 -> Biological process: GO:0015031 [protein transport] evidence: IEA
GeneID:5865 -> Biological process: GO:0017157 [regulation of exocytosis] evidence: IEA
GeneID:5865 -> Biological process: GO:0018125 [peptidyl-cysteine methylation] evidence: IEA
GeneID:5865 -> Cellular component: GO:0005829 [cytosol] evidence: IEA
GeneID:5865 -> Cellular component: GO:0005886 [plasma membrane] evidence: IEA
GeneID:5865 -> Cellular component: GO:0008021 [synaptic vesicle] evidence: IEA
GeneID:5865 -> Cellular component: GO:0030141 [secretory granule] evidence: IEA
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