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2019-03-23 03:04:04, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_002839              10127 bp    mRNA    linear   PRI 15-JUN-2013
DEFINITION  Homo sapiens protein tyrosine phosphatase, receptor type, D
            (PTPRD), transcript variant 1, mRNA.
ACCESSION   NM_002839
VERSION     NM_002839.3  GI:283484017
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 10127)
  AUTHORS   Wu,J.H., Lemaitre,R.N., Manichaikul,A., Guan,W., Tanaka,T., Foy,M.,
            Kabagambe,E.K., Djousse,L., Siscovick,D., Fretts,A.M., Johnson,C.,
            King,I.B., Psaty,B.M., McKnight,B., Rich,S.S., Chen,Y.D.,
            Nettleton,J.A., Tang,W., Bandinelli,S., Jacobs,D.R. Jr.,
            Browning,B.L., Laurie,C.C., Gu,X., Tsai,M.Y., Steffen,L.M.,
            Ferrucci,L., Fornage,M. and Mozaffarian,D.
  TITLE     Genome-wide association study identifies novel loci associated with
            concentrations of four plasma phospholipid fatty acids in the de
            novo lipogenesis pathway: results from the Cohorts for Heart and
            Aging Research in Genomic Epidemiology (CHARGE) consortium
  JOURNAL   Circ Cardiovasc Genet 6 (2), 171-183 (2013)
   PUBMED   23362303
REFERENCE   2  (bases 1 to 10127)
  AUTHORS   Du,Y., Su,T., Tan,X., Li,X., Xie,J., Wang,G., Shen,J., Hou,J. and
            Cao,G.
  TITLE     Polymorphism in protein tyrosine phosphatase receptor delta is
            associated with the risk of clear cell renal cell carcinoma
  JOURNAL   Gene 512 (1), 64-69 (2013)
   PUBMED   23069849
  REMARK    GeneRIF: Polymorphism in protein tyrosine phosphatase receptor
            delta is associated with the risk of clear cell renal cell
            carcinoma.
REFERENCE   3  (bases 1 to 10127)
  AUTHORS   Meng,W., Butterworth,J., Bradley,D.T., Hughes,A.E., Soler,V.,
            Calvas,P. and Malecaze,F.
  TITLE     A genome-wide association study provides evidence for association
            of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in
            the French Population
  JOURNAL   Invest. Ophthalmol. Vis. Sci. 53 (13), 7983-7988 (2012)
   PUBMED   23049088
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 10127)
  AUTHORS   Wilk,J.B., Shrine,N.R., Loehr,L.R., Zhao,J.H., Manichaikul,A.,
            Lopez,L.M., Smith,A.V., Heckbert,S.R., Smolonska,J., Tang,W.,
            Loth,D.W., Curjuric,I., Hui,J., Cho,M.H., Latourelle,J.C.,
            Henry,A.P., Aldrich,M., Bakke,P., Beaty,T.H., Bentley,A.R.,
            Borecki,I.B., Brusselle,G.G., Burkart,K.M., Chen,T.H., Couper,D.,
            Crapo,J.D., Davies,G., Dupuis,J., Franceschini,N., Gulsvik,A.,
            Hancock,D.B., Harris,T.B., Hofman,A., Imboden,M., James,A.L.,
            Khaw,K.T., Lahousse,L., Launer,L.J., Litonjua,A., Liu,Y.,
            Lohman,K.K., Lomas,D.A., Lumley,T., Marciante,K.D., McArdle,W.L.,
            Meibohm,B., Morrison,A.C., Musk,A.W., Myers,R.H., North,K.E.,
            Postma,D.S., Psaty,B.M., Rich,S.S., Rivadeneira,F., Rochat,T.,
            Rotter,J.I., Artigas,M.S., Starr,J.M., Uitterlinden,A.G.,
            Wareham,N.J., Wijmenga,C., Zanen,P., Province,M.A., Silverman,E.K.,
            Deary,I.J., Palmer,L.J., Cassano,P.A., Gudnason,V., Barr,R.G.,
            Loos,R.J., Strachan,D.P., London,S.J., Boezen,H.M.,
            Probst-Hensch,N., Gharib,S.A., Hall,I.P., O'Connor,G.T., Tobin,M.D.
            and Stricker,B.H.
  TITLE     Genome-wide association studies identify CHRNA5/3 and HTR4 in the
            development of airflow obstruction
  JOURNAL   Am. J. Respir. Crit. Care Med. 186 (7), 622-632 (2012)
   PUBMED   22837378
REFERENCE   5  (bases 1 to 10127)
  AUTHORS   Comuzzie,A.G., Cole,S.A., Laston,S.L., Voruganti,V.S., Haack,K.,
            Gibbs,R.A. and Butte,N.F.
  TITLE     Novel genetic loci identified for the pathophysiology of childhood
            obesity in the Hispanic population
  JOURNAL   PLoS ONE 7 (12), E51954 (2012)
   PUBMED   23251661
REFERENCE   6  (bases 1 to 10127)
  AUTHORS   Blanchetot,C., Tertoolen,L.G., Overvoorde,J. and den Hertog,J.
  TITLE     Intra- and intermolecular interactions between intracellular
            domains of receptor protein-tyrosine phosphatases
  JOURNAL   J. Biol. Chem. 277 (49), 47263-47269 (2002)
   PUBMED   12376545
  REMARK    GeneRIF: interactions between RPTP-domain1s and RPTP-domain 2s are
            a common but specific mechanism that is likely to be regulated-
            domain2s and the wedge structures are crucial determinants of
            binding specificity, thus regulating cross-talk between RPTPs
REFERENCE   7  (bases 1 to 10127)
  AUTHORS   Wallace,M.J., Fladd,C., Batt,J. and Rotin,D.
  TITLE     The second catalytic domain of protein tyrosine phosphatase delta
            (PTP delta) binds to and inhibits the first catalytic domain of PTP
            sigma
  JOURNAL   Mol. Cell. Biol. 18 (5), 2608-2616 (1998)
   PUBMED   9566880
REFERENCE   8  (bases 1 to 10127)
  AUTHORS   Pulido,R., Serra-Pages,C., Tang,M. and Streuli,M.
  TITLE     The LAR/PTP delta/PTP sigma subfamily of transmembrane
            protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and
            PTP sigma isoforms are expressed in a tissue-specific manner and
            associate with the LAR-interacting protein LIP.1
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 92 (25), 11686-11690 (1995)
   PUBMED   8524829
REFERENCE   9  (bases 1 to 10127)
  AUTHORS   Pulido,R., Krueger,N.X., Serra-Pages,C., Saito,H. and Streuli,M.
  TITLE     Molecular characterization of the human transmembrane
            protein-tyrosine phosphatase delta. Evidence for tissue-specific
            expression of alternative human transmembrane protein-tyrosine
            phosphatase delta isoforms
  JOURNAL   J. Biol. Chem. 270 (12), 6722-6728 (1995)
   PUBMED   7896816
REFERENCE   10 (bases 1 to 10127)
  AUTHORS   Krueger,N.X., Streuli,M. and Saito,H.
  TITLE     Structural diversity and evolution of human receptor-like protein
            tyrosine phosphatases
  JOURNAL   EMBO J. 9 (10), 3241-3252 (1990)
   PUBMED   2170109
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC028038.1, AL390723.21,
            AB211400.1, AL356584.21, AL445926.5 and BM680342.1.
            On Jan 8, 2010 this sequence version replaced gi:104487003.
            
            Summary: The protein encoded by this gene is a member of the
            protein tyrosine phosphatase (PTP) family. PTPs are known to be
            signaling molecules that regulate a variety of cellular processes
            including cell growth, differentiation, mitotic cycle, and
            oncogenic transformation. This PTP contains an extracellular
            region, a single transmembrane segment and two tandem
            intracytoplasmic catalytic domains, and thus represents a
            receptor-type PTP. The extracellular region of this protein is
            composed of three Ig-like and eight fibronectin type III-like
            domains. Studies of the similar genes in chicken and fly suggest
            the role of this PTP is in promoting neurite growth, and regulating
            neurons axon guidance. Multiple alternatively spliced transcript
            variants of this gene have been reported. A related pseudogene has
            been identified on chromosome 5. [provided by RefSeq, Jan 2010].
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: AB211400.1, L38929.1 [ECO:0000331]
            RNAseq introns       :: mixed/partial sample support ERS025081,
                                    ERS025082 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-215               BC028038.1         1-215
            216-216             AL390723.21        23944-23944         c
            217-1703            AB211400.1         185-1671
            1704-1704           AL356584.21        20392-20392         c
            1705-6657           AB211400.1         1673-6625
            6658-9471           AL445926.5         119217-122030       c
            9472-10127          BM680342.1         1-656               c
FEATURES             Location/Qualifiers
     source          1..10127
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9p23-p24.3"
     gene            1..10127
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="protein tyrosine phosphatase, receptor type, D"
                     /db_xref="GeneID:5789"
                     /db_xref="HGNC:9668"
                     /db_xref="HPRD:03358"
                     /db_xref="MIM:601598"
     exon            1..36
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            37..144
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            145..199
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            200..272
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            273..376
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            377..418
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            419..457
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            458..507
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            508..541
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            542..601
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            602..640
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            641..807
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    660..662
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="upstream in-frame stop codon"
     CDS             744..6482
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /EC_number="3.1.3.48"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; protein tyrosine phosphatase, receptor type,
                     delta polypeptide; receptor-type tyrosine-protein
                     phosphatase delta; R-PTP-delta; protein-tyrosine
                     phosphatase delta"
                     /codon_start=1
                     /product="receptor-type tyrosine-protein phosphatase delta
                     isoform 1 precursor"
                     /protein_id="NP_002830.1"
                     /db_xref="GI:4506309"
                     /db_xref="CCDS:CCDS43786.1"
                     /db_xref="GeneID:5789"
                     /db_xref="HGNC:9668"
                     /db_xref="HPRD:03358"
                     /db_xref="MIM:601598"
                     /translation="
MVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAESDSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYAT
"
     sig_peptide     744..803
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
     mat_peptide     804..6479
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /product="receptor-type tyrosine-protein phosphatase delta
                     isoform 1"
     misc_feature    813..1088
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Immunoglobulin I-set domain; Region: I-set;
                     pfam07679"
                     /db_xref="CDD:191810"
     misc_feature    831..1088
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Immunoglobulin; Region: IG; smart00409"
                     /db_xref="CDD:197707"
     misc_feature    1170..1415
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Second immunoglobulin (Ig)-like domain of  the
                     receptor protein tyrosine phosphatase (RPTP)-F, also known
                     as LAR; Region: Ig2_RPTP_IIa_LAR_like; cd05738"
                     /db_xref="CDD:143215"
     misc_feature    1281..1310
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (P23468.2);
                     Region: Interaction with IL1RAPL1 (By similarity)"
     misc_feature    1455..1700
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Immunoglobulin I-set domain; Region: I-set;
                     pfam07679"
                     /db_xref="CDD:191810"
     misc_feature    1491..1697
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Third immunoglobulin (Ig)-like domain of the
                     receptor protein tyrosine phosphatase (RPTP)-F, also known
                     as LAR; Region: Ig3_RPTP_IIa_LAR_like; cd05739"
                     /db_xref="CDD:143216"
     misc_feature    1710..1979
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; Region: FN3; cd00063"
                     /db_xref="CDD:28945"
     misc_feature    order(1710..1712,1896..1898,1941..1943)
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Interdomain contacts; other site"
                     /db_xref="CDD:28945"
     misc_feature    order(1944..1949,1953..1958)
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Cytokine receptor motif; other site"
                     /db_xref="CDD:28945"
     misc_feature    1998..2276
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; Region: FN3; cd00063"
                     /db_xref="CDD:28945"
     misc_feature    order(2193..2195,2238..2240)
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Interdomain contacts; other site"
                     /db_xref="CDD:28945"
     misc_feature    order(2241..2246,2250..2255)
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Cytokine receptor motif; other site"
                     /db_xref="CDD:28945"
     misc_feature    2289..2555
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; Region: FN3; cd00063"
                     /db_xref="CDD:28945"
     misc_feature    order(2289..2291,2472..2474,2517..2519)
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Interdomain contacts; other site"
                     /db_xref="CDD:28945"
     misc_feature    order(2520..2525,2529..2534)
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Cytokine receptor motif; other site"
                     /db_xref="CDD:28945"
     misc_feature    2577..2861
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; Region: FN3; cd00063"
                     /db_xref="CDD:28945"
     misc_feature    order(2778..2780,2823..2825)
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Interdomain contacts; other site"
                     /db_xref="CDD:28945"
     misc_feature    order(2826..2831,2835..2840)
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Cytokine receptor motif; other site"
                     /db_xref="CDD:28945"
     misc_feature    2880..3200
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; Region: FN3; cd00063"
                     /db_xref="CDD:28945"
     misc_feature    order(3117..3119,3162..3164)
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Interdomain contacts; other site"
                     /db_xref="CDD:28945"
     misc_feature    order(3165..3170,3174..3179)
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Cytokine receptor motif; other site"
                     /db_xref="CDD:28945"
     misc_feature    3213..3458
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; Region: FN3; cd00063"
                     /db_xref="CDD:28945"
     misc_feature    order(3213..3215,3402..3404,3447..3449)
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Interdomain contacts; other site"
                     /db_xref="CDD:28945"
     misc_feature    3450..3455
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Cytokine receptor motif; other site"
                     /db_xref="CDD:28945"
     misc_feature    3507..3782
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; Region: FN3; cd00063"
                     /db_xref="CDD:28945"
     misc_feature    order(3699..3701,3744..3746)
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Interdomain contacts; other site"
                     /db_xref="CDD:28945"
     misc_feature    order(3747..3752,3756..3761)
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Cytokine receptor motif; other site"
                     /db_xref="CDD:28945"
     misc_feature    3807..>4001
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Fibronectin type 3 domain; One of three types of
                     internal repeats found in the plasma protein fibronectin.
                     Its tenth fibronectin type III repeat contains an RGD cell
                     recognition sequence in a flexible loop between 2 strands.
                     Approximately 2% of all...; Region: FN3; cd00063"
                     /db_xref="CDD:28945"
     misc_feature    4284..4289
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Cleavage (Probable); propagated from
                     UniProtKB/Swiss-Prot (P23468.2); cleavage site"
     misc_feature    4539..4613
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (P23468.2);
                     transmembrane region"
     misc_feature    4809..5576
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Protein tyrosine phosphatase, catalytic domain;
                     Region: PTPc; smart00194"
                     /db_xref="CDD:197567"
     misc_feature    4887..5576
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Protein tyrosine phosphatases (PTP) catalyze the
                     dephosphorylation of phosphotyrosine peptides; they
                     regulate phosphotyrosine levels in signal transduction
                     pathways. The depth of the active site cleft renders the
                     enzyme specific for phosphorylated Tyr; Region: PTPc;
                     cd00047"
                     /db_xref="CDD:28929"
     misc_feature    order(5304..5306,5397..5402,5409..5411,5418..5423)
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="active site"
                     /db_xref="CDD:28929"
     misc_feature    5400..5420
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (P23468.2);
                     Region: Substrate binding (By similarity)"
     misc_feature    5670..6449
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Protein tyrosine phosphatase, catalytic domain;
                     Region: PTPc; smart00194"
                     /db_xref="CDD:197567"
     misc_feature    5757..6449
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="Protein tyrosine phosphatases (PTP) catalyze the
                     dephosphorylation of phosphotyrosine peptides; they
                     regulate phosphotyrosine levels in signal transduction
                     pathways. The depth of the active site cleft renders the
                     enzyme specific for phosphorylated Tyr; Region: PTPc;
                     cd00047"
                     /db_xref="CDD:28929"
     misc_feature    order(6171..6173,6270..6275,6282..6284,6291..6296)
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /note="active site"
                     /db_xref="CDD:28929"
     exon            808..953
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            954..1095
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            1096..1284
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     STS             1252..1523
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /standard_name="GDB:582179"
                     /db_xref="UniSTS:157878"
     exon            1285..1293
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            1294..1311
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            1312..1422
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            1423..1434
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            1435..1704
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            1705..2286
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     variation       1739
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3763653"
     STS             2271..3869
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /standard_name="GDB:582186"
                     /db_xref="UniSTS:157880"
     exon            2287..2420
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            2421..2565
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            2566..2871
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            2872..3065
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     STS             2885..3202
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /standard_name="GDB:582183"
                     /db_xref="UniSTS:157879"
     exon            3066..3092
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            3093..3210
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            3211..3798
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     variation       3632
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3824417"
     exon            3799..3896
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            3897..4156
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            4157..4247
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            4248..4457
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            4458..4618
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            4619..4731
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            4732..4829
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            4830..4953
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            4954..5129
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            5130..5249
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            5250..5404
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            5405..5690
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            5691..5869
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     STS             5763..5981
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /standard_name="PTPRD"
                     /db_xref="UniSTS:512659"
     exon            5870..5996
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     STS             5957..6462
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /standard_name="Ptprd"
                     /db_xref="UniSTS:545976"
     exon            5997..6122
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            6123..6277
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            6278..6413
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     exon            6414..10110
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /inference="alignment:Splign:1.39.8"
     STS             6493..6933
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /standard_name="SGC35386"
                     /db_xref="UniSTS:31522"
     variation       7383
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1051863"
     STS             7447..7465
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /db_xref="UniSTS:98954"
     variation       8078
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11542527"
     polyA_signal    8098..8103
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
     polyA_site      8122
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
     STS             8420..8600
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /standard_name="D9S1044E"
                     /db_xref="UniSTS:151264"
     STS             8455..8627
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /standard_name="RH47322"
                     /db_xref="UniSTS:12791"
     variation       8696
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1065682"
     STS             9056..9173
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /standard_name="A003M12"
                     /db_xref="UniSTS:64813"
     STS             9119..9260
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /standard_name="G31002"
                     /db_xref="UniSTS:79310"
     variation       9368
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:3739579"
     polyA_signal    10088..10093
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
     polyA_site      10110
                     /gene="PTPRD"
                     /gene_synonym="HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA"
ORIGIN      
cggcgccgccagccagcctcggcggggagagtgcagtttattctgggcctgtgtggaatagaaagacaattctttatttgactggtaggaaagaaaagagaagactcctcagggtttccaaggaggactggagcggctgctttagtgaagaagtgaagaatcaaggaagtaaaggacctgtctcaaagtcacacaactaggaaatcttgaggagtctgatacttttcatcctccagctataaaatcatcttgtagggggaagctgtacattggtggaaaataaaaggcaagcagttcctggcccgtgatattccagttagaggtgtctgactgacagcatgttggcaccgagggaagcgatgggcttcggctccaggtttctgtcctgagaccacagcagaatgtgccttggacaaaggcttggactccttgatcttctggtaacttcaaaaatctggtctcagggtggtgaactttttcttcgaattcctaacctgtgagcttacgatgatggtgcctgtccattaactgaacaactgtggttttgaacttcttgaggccagggactgtgtctgaaaacaccgacggtggctaactcaagggagacgtctggtgaacacccgtgggatctaaagaacaagctctgaaagtgttccagctgaaatttcagatcggacagactcgctgcggctccggaggcagtgattccaagctgctcgcgcacgctgctgccaagctgcaggatggtgcacgtagccaggctgctgctgctgctcctcactttcttcctccgcacggatgctgagacacctccaaggtttacacgaacacccgttgatcagacaggggtctctggcggagttgcctctttcatctgccaagctacgggagacccaagacctaaaattgtctggaacaaaaaaggaaagaaagtcagcaatcagagatttgaggtaatagagtttgacgatgggtctggatcagttctcagaatacaacccttacggactccgagggatgaggccatttatgaatgtgtggcctcaaataatgtgggagaaataagtgtatccaccagactcacagttttgcgggaagatcaaattcccaggggcttccctaccattgacatgggcccacagttgaaggtggttgagcgtactcgcacggccaccatgctttgtgcagccagtggtaatccggatccagaaatcacttggtttaaagatttcttacctgtggacacaagcaacaacaatggtcgtattaagcagttacgatcagaatctattggtggtacaccaataagaggagcccttcagattgagcagagtgaagagtctgaccaaggaaaatatgagtgtgttgccaccaacagcgcgggcactcgctattccgctcctgccaatttatatgtcagagagctgcgagaagttcgccgtgtcccaccaagattctctatcccacccactaatcatgaaatcatgccaggcggaagcgttaatatcacctgtgtggccgtggggtcaccaatgccttatgtaaagtggatgttgggggcagaagatctgacacctgaagatgatatgccaataggaagaaatgtgctagaactgaatgatgtaagacagtcagcaaattacacctgtgttgctatgtcaacactgggtgtcattgaagcaatagcacagatcactgtcaaagccttacccaaacctccaggaactcctgtagtgaccgagagcacagctacaagcatcacactgacgtgggactctgggaaccctgagcctgtttcttattacataattcagcataaacctaaaaactctgaggaactttacaaagaaattgatggggtggcgaccacacgctacagtgtcgctggactaagtccctactcggattatgaattcagggttgttgctgtcaataacattgggcgggggcctcccagcgaacctgtgctaacacaaacctcagagcaagcaccatccagtgccccgagggatgtccaggcacgaatgttgagttcgaccaccattttggtacagtggaaggaacctgaagagccaaatggacagatccaaggatatagagtttattatacaatggatcccactcaacatgtcaacaactggatgaaacacaatgtagctgacagccaaatcactactattggcaacttagtgccccagaaaacatattctgtcaaagtcctggcttttacctcaattggagatggtcccctttcaagtgacatacaagtcatcactcagacaggagtaccagggcagccactaaacttcaaagcagaacctgagtctgaaacaagtattttgctctcttggacacctccacgttcagataccattgccaactatgaactggtctacaaagatggggagcatggagaggagcaacgaattaccattgagccagggacatcatataggctgcaaggactgaaaccaaacagcttatactatttccgtctggctgcacgctcccctcaaggcctgggtgcttctactgcagaaatatcagctagaaccatgcagtcaaagccgtcagctcctcctcaagacattagttgcaccagcccaagttccactagtattttggtaagttggcaacctccaccagtggaaaaacagaatggcattatcactgaatactccatcaagtacactgcagtggatggggaagatgacaagcctcacgagattttgggaattccttcggacactaccaaataccttttggaacagctggaaaaatggactgaataccggatcactgtgacagcccatacagatgtcggccctggccctgagagcttgtccgtgttgattcgaaccaatgaagatgttcctagtggtcctcctcgcaaagtcgaggtagaggctgtcaactcaacatctgttaaagtctcatggcgctcacccgtgcccaataaacagcatggccagataagaggatatcaggtgcattatgtgaggatggaaaatggtgagcccaagggccagcccatgctgaaagatgtcatgctggctgatgcacagtgggaatttgatgatactactgaacatgacatgatcatttctgggctccagcctgaaacttcctactccctcaccgtcacagcctacacaaccaaaggagatggtgctcgcagcaagcccaaactggtgtccaccactggggcagttccagggaaacctcggcttgtgattaaccacactcagatgaatactgctcttattcagtggcaccctccggtggacacatttggacctcttcagggctaccgtctaaaatttggccgcaaggatatggagccacttactactcttgagttctctgaaaaagaagatcactttacagctacagacatccacaagggagcatcatacgtcttcaggctctcagccagaaacaaagtgggctttggggaggagatggtgaaggagatttccattccagaagaagtaccaactggattccctcaaaaccttcactcagaaggcaccacttcaacctccgtccagttatcttggcaaccacctgtcctggcagagagaaatggcattatcaccaagtatacccttctttatagggatatcaacatcccccttctcccgatggagcagcttattgttccagctgacaccactatgacactcactggcttaaaaccagataccacatacgatgtaaaagtacgtgctcatacgagcaaagggcccgggccatatagtcccagtgtccagttcaggacactgcctgtggatcaagtgtttgcaaaaaattttcatgtcaaagcagtaatgaagacttccgtgttgctgtcttgggagattccagagaattataactccgccatgcctttcaaaattctttatgatgatgggaaaatggtagaagaagtggatggccgagccacacagaagttaattgtcaacctgaagcctgagaaatcatattcatttgtgctgacaaatcgtggaaacagtgctggtgggctgcagcacagggtcacggcaaagactgcaccagatgtattacgtaccaagcctgccttcattgggaagaccaacttggatggcatgattactgtgcaactgcctgaagtacctgcaaatgagaatataaaaggttactacataataattgtgcctttgaagaaatctcgcgggaaatttatcaagccatgggagagtccagatgaaatggaattagatgagctgcttaaggagatatctaggaagcgcagaagcatccgttatgggagagaagttgaattaaagccatatattgccgctcactttgatgtccttcccactgagttcaccctgggggatgacaagcattatggtggatttacaaacaagcaactccaaagtggtcaagaatatgtcttctttgtgttagcagtaatggaacatgcagagtctaagatgtatgcaaccagcccttactccgaccccgtggtgtcaatggatctggatccgcagccaatcacggatgaagaagaaggcttgatctgggttgtaggtcctgtccttgcagtggtctttatcatctgcattgtcattgctattcttctttataaaaggaagagggcagagtccgactctagaaaaagcagcataccgaacaataaggagatcccttcacaccacccaacagaccctgtagaactgaggcgccttaactttcaaacaccgggtatggctagccatcctccaatacccatcttggaacttgcagaccacattgaaagattgaaagcaaatgacaacttgaagttttcccaggaatatgagtcaattgaccctggccagcagttcacttgggaacattcaaacttggaagtaaacaaaccaaagaatagatacgcgaatgtaatcgcatatgatcattcccgggttctcctatcagctatagaagggatcccaggaagtgactatgtgaatgccaactacatagatgggtataggaagcaaaatgcctatattgcaacacagggatctctccccgaaacatttggggacttttggagaatgatatgggaacaacggagtgccacagttgtcatgatgacaaaactagaagaaagatcaagggtgaagtgtgaccagtattggcctagcagaggcacagaaacccacggactcgttcaagtaacgctgcttgatactgtggagctggccacatattgtgttcgaacatttgcactttacaagaatggttcaagtgagaagagagaagtgagacaattccagttcaccgcctggcctgatcatggtgttccagaacaccctacaccttttctagctttcttacgtagagtcaaaacctgtaaccctcccgatgctggtccgatggttgtgcactgcagtgcgggagttggccggactggttgcttcatcgtcatagatgccatgttagaaagaataaagcatgaaaaaactgtagatatttatggccatgtaactttaatgagagcccagaggaactatatggttcaaacagaagaccaatacatctttatccatgatgcactgttagaagcagtgacttgtggaaataccgaagtgccagctagaaacttgtatgcctacattcagaagctgacacaaatagaaacgggagagaatgtcacaggaatggagctcgaatttaagcgtctagccagctcaaaagctcacacctcaaggtttatcagtgccaatcttccatgtaataaattcaaaaatcgccttgttaatattatgccatatgaatccacaagggtatgcctgcagcctatccgtggagtagaaggatctgattacatcaatgccagttttattgatggatacagacaacagaaagcctacatcgctacccaggggcccttggcagagaccactgaagacttctggcggatgctctgggaacacaattccaccatagttgtgatgctcaccaagctgcgtgaaatgggcagagagaaatgtcaccaatactggccagcagaacggtctgcaagataccagtactttgttgtagatcccatggctgagtacaacatgccacagtatatcctaagggaattcaaggtcacagatgccagggacggccagtcccgaacagtaaggcagttccagttcactgactggccagagcaaggagtgccaaagtccggagaaggatttattgacttcatcggccaagtccataaaacaaaagaacagtttggccaagatggacccatttcagtccattgcagcgcgggcgttggaagaactggagtcttcataacgctaagcattgttttggaaagaatgagatatgaaggagttgtagatatcttccagactgtcaaaatgttaagaacacaacgaccagctatggtacagacagaggatcaatatcagttttcctatcgtgccgcactagagtacctgggcagctttgaccactatgcaacgtagaaacccctgacccattctggatttttactacaggcccttcaatatccatggagtctcttctgagccatacagggcacttgagaagtccttcttaacttctagctaacaactacttagtgggactattacacacaaaacaaattaaaaacaaattattccaggtggaccaagaattcacagtttaataatctaacctgaaaaataatgaagagaatcctgactgatgaggcatctgaaggattttatttacagatacctcaaggattcaaaatcaagggaagaagaaatcacagcaaagaaccaccatcttattcaggattgcttgaaaggtgcaaggagaaattgccagaatgctgcagttcagcacaagatatgtgctggtgtggcttctcacaatgaaacggactctgctttgacatcgccccttcccaccatactgctcataataacattttagggggaaaggggagggaatgtttaaaaagaaagtccttgatttagttttttagtattgtaaagatactgctgacctgtgcttcatttctaactgtgtaaacttttttttaacaaaatgtatcattcgataaagtgaattttaaaaaagttacataactcttcatttttttatttccaaatcgtaggtttttttaagctgtagaactgttatctgtaatatcttgctgtagaaatatcaaatcatttgaaaatttgcacatttttgtgcaaaactcaatctacagtatcagtctcgtcagatatattaattttacacttcagttttgattggtgagaaagtacccattctcttcaaataatcaaagataattattattttgttttgtttttggaatcaacagggaggcgcaaagtataaagttgctgctaacatatatacatatatatccatattttataagggtgtctatgtatatatagacagtgtgtccacacaaaaaatagatacagttatcagtcagtcagttcttccatgatttagtttttttaaacgtagaaaagctattgtaaacatctctttccatttattcttaattttttgacatattggtatttctttaaagggaaatgaggaatgcacatcagtgattgattgtcaaacctcaccccctgatttcctacctaatctacccccacctaaccaatcaatcacatccacaaattgttttgtttgtttgttagtcaggcttccaacaaagttcaatatttctaacactctagtgcaataaaaattattattaaatagctaagaggtgtgcatgtgggaaaggtcagtgcatatccctttaggaggggagaatgttgtaatatatcagctatcgagttgtttaaaaaaagtgtattcaatcgtatattgtctatagtatgtgctatgaaatttgcatttatgatatgtaacaggggcaaagccaaattcatgttactctgttcagtcagaaacattttgtggcatacagcattcctgggaagtgctgtactttgtttcgttttggttttagttttgcatttagagtgccttataattgatgcctattttaatagcatttctttttagcttttggttcgtatttccattcactgttcgtatctgttactttctattaaagcattatctgtttaccacatgtacaaaaactctttgaataatatgcattcctagttttcagccaagtcggggatgttagtgattgtaccagcccaaagcacttggataatcagggcccttcttccttttataatcaatcatcaacatcagaaaaagctacttgttttatttatattcccttccaaatccgctctggaacatgcagtaactgcaccaaacttattttagtaacaaatatcattggcaactttggaatatatttgatattccattaggatttttctaaaaggggaaataaactatatatatatatgtatcttacccccaattcttccaacagaatttctataggaagccatggatgatggcataagtttgccacatattacatgattttaaataatcctcaaaatacccaaggaactcttaaagagttttggtatgagtatactactttggtttaattttagcttcatggatgttctgcatggaaggatttttgttttccacattttcccattgctagcagagtgaaatccaagagaccaaacatttgcaagcattgtatttgagcacttttgtaaaaaacaaagaaaaagaaaaaaaagaaaatatatataatactaaaaaaaagtatctagaaggctacctcagaatgagactctctaacctacatcagaaccagagaagaatgtgcactatgtgggtctgttatcattattttcttttagtttgtatctttttggagatttatccaagtgccagattactcagtgctataattttcttttagttaaacaaagggggtcagacagacattgcatcatccagacatgccttgttggacatgtagaatccgatggagcactgcacaccagaatgattggccaatgagcagcttctctccctgaaacaataactgcccatttggcaaagggaaagatgacaataatcagaagaagaaaatgaatgggatgcataccatagacgaacgaggcggagactattgcgggaatcttactgttcaggagctgttcctagaactaactcccttactgtcattgatgtgcattccactctgtgcttttctgtacaaccattcaagttttaatttcccaggtgaaccatctttatctgccattaccacaagctttcaagtttccagttattttcatcatcataaccagtacggtgctattatttacctatgtacgtgtagttatgtataattttgtaattagttacaatggtaaaaaaaatcaaaatatataaaaagtgatttgtacagaactttattttagctcttttttaaaaatgatttgcatggttagaaaacggcgaggacagccaggggagggaagggcctctagggaactttgcactttctatacctttgtactatgcactgccctattgattctacacccaataatgatattacttgaacccatctgtaagaaactgcttcggaaattcatttgtgtgtatgtaaataacacaacatagaaacaggaagggaaaaaagtctgcagtaatgcacgtattttttttctttcctgtttattttcggttttgctttaagtccttttatttttaattccctttttgtttttctttttgggttttggttccttttgggtttatgggtgccctgatactccagcagagatcagaaggctacagatccattctatccatccgttatgtggctttgccatcccagcttggagtgtctttacaaagataataacagttgtgttctttgctctcgttttggatgcatagactgaaaaattaaaacaaataacttgtaaaatggcttgttaaaaaatacaattacctctaattagtagtacgcgtaaatgttttacagaatgaaaggcgtgctttttattttcttacttcgttacattggtggcgaaagaagtctgtatgaaaatcagttctttgctgacacaagttccatttgttacaaatgaattctaataaaaatgtcagtgttatgcaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:5789 -> Molecular function: GO:0005001 [transmembrane receptor protein tyrosine phosphatase activity] evidence: TAS
            GeneID:5789 -> Molecular function: GO:0005102 [receptor binding] evidence: ISS
            GeneID:5789 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:5789 -> Molecular function: GO:0050839 [cell adhesion molecule binding] evidence: ISS
            GeneID:5789 -> Biological process: GO:0006470 [protein dephosphorylation] evidence: TAS
            GeneID:5789 -> Biological process: GO:0006796 [phosphate-containing compound metabolic process] evidence: NAS
            GeneID:5789 -> Biological process: GO:0007157 [heterophilic cell-cell adhesion] evidence: ISS
            GeneID:5789 -> Biological process: GO:0007185 [transmembrane receptor protein tyrosine phosphatase signaling pathway] evidence: TAS
            GeneID:5789 -> Biological process: GO:0030182 [neuron differentiation] evidence: ISS
            GeneID:5789 -> Biological process: GO:0050775 [positive regulation of dendrite morphogenesis] evidence: ISS
            GeneID:5789 -> Biological process: GO:0097105 [presynaptic membrane assembly] evidence: ISS
            GeneID:5789 -> Cellular component: GO:0005887 [integral to plasma membrane] evidence: TAS
ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_002830 -> EC 3.1.3.48

by @meso_cacase at DBCLS
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