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2024-04-26 06:39:32, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_002829 6734 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens protein tyrosine phosphatase, non-receptor type 3
(PTPN3), transcript variant 1, mRNA.
ACCESSION NM_002829
VERSION NM_002829.3 GI:223941875
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6734)
AUTHORS Hou,S., Suresh,P.S., Qi,X., Lepp,A., Mirza,S.P. and Chen,G.
TITLE p38gamma Mitogen-activated protein kinase signals through
phosphorylating its phosphatase PTPH1 in regulating ras protein
oncogenesis and stress response
JOURNAL J. Biol. Chem. 287 (33), 27895-27905 (2012)
PUBMED 22730326
REMARK GeneRIF: p38gamma Mitogen-activated protein kinase signals through
phosphorylating its phosphatase PTPH1 in regulating ras protein
oncogenesis and stress response.
REFERENCE 2 (bases 1 to 6734)
AUTHORS Jung,Y., Kim,P., Jung,Y., Keum,J., Kim,S.N., Choi,Y.S., Do,I.G.,
Lee,J., Choi,S.J., Kim,S., Lee,J.E., Kim,J., Lee,S. and Kim,J.
TITLE Discovery of ALK-PTPN3 gene fusion from human non-small cell lung
carcinoma cell line using next generation RNA sequencing
JOURNAL Genes Chromosomes Cancer 51 (6), 590-597 (2012)
PUBMED 22334442
REMARK GeneRIF: The fusion transcript of ALK and PTPN3 identified resulted
from translocation of a part of ALK gene into the third intron of
PTPN3. Analysis of the transcript sequence indicates that no
protein with any enzymatic activity is produced.
REFERENCE 3 (bases 1 to 6734)
AUTHORS Zhi,H.Y., Hou,S.W., Li,R.S., Basir,Z., Xiang,Q., Szabo,A. and
Chen,G.
TITLE PTPH1 cooperates with vitamin D receptor to stimulate breast cancer
growth through their mutual stabilization
JOURNAL Oncogene 30 (14), 1706-1715 (2011)
PUBMED 21119599
REMARK GeneRIF: PTPH1 stimulated breast cancer growth through regulating
vitamin D receptor expression. PTPH1 was overexpressed in primary
breast cancer and levels of its protein expression positively
correlated with clinical metastasis.
REFERENCE 4 (bases 1 to 6734)
AUTHORS Hou,S.W., Zhi,H.Y., Pohl,N., Loesch,M., Qi,X.M., Li,R.S., Basir,Z.
and Chen,G.
TITLE PTPH1 dephosphorylates and cooperates with p38gamma MAPK to
increase ras oncogenesis through PDZ-mediated interaction
JOURNAL Cancer Res. 70 (7), 2901-2910 (2010)
PUBMED 20332238
REMARK GeneRIF: PTPH1 plays a role in Ras-dependent malignant growth by a
mechanism depending on its p38gamma-binding activity. Ras increases
p38gamma and PTPH1 expression and there is a coupling of increased
p38gamma and PTPH1 protein expression in colon cancer.
REFERENCE 5 (bases 1 to 6734)
AUTHORS Barr,A.J., Ugochukwu,E., Lee,W.H., King,O.N., Filippakopoulos,P.,
Alfano,I., Savitsky,P., Burgess-Brown,N.A., Muller,S. and Knapp,S.
TITLE Large-scale structural analysis of the classical human protein
tyrosine phosphatome
JOURNAL Cell 136 (2), 352-363 (2009)
PUBMED 19167335
REFERENCE 6 (bases 1 to 6734)
AUTHORS Zhang,S.H., Kobayashi,R., Graves,P.R., Piwnica-Worms,H. and
Tonks,N.K.
TITLE Serine phosphorylation-dependent association of the band
4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3beta
protein
JOURNAL J. Biol. Chem. 272 (43), 27281-27287 (1997)
PUBMED 9341175
REFERENCE 7 (bases 1 to 6734)
AUTHORS Ikuta,S., Itoh,F., Hinoda,Y., Toyota,M., Makiguchi,Y., Imai,K. and
Yachi,A.
TITLE Expression of cytoskeletal-associated protein tyrosine phosphatase
PTPH1 mRNA in human hepatocellular carcinoma
JOURNAL J. Gastroenterol. 29 (6), 727-732 (1994)
PUBMED 7874267
REFERENCE 8 (bases 1 to 6734)
AUTHORS Itoh,F., Ikuta,S., Hinoda,Y., Arimura,Y., Ohe,M., Adachi,M.,
Ariyama,T., Inazawa,J., Imai,K. and Yachi,A.
TITLE Expression and chromosomal assignment of PTPH1 gene encoding a
cytosolic protein tyrosine phosphatase homologous to
cytoskeletal-associated proteins
JOURNAL Int. J. Cancer 55 (6), 947-951 (1993)
PUBMED 8253532
REFERENCE 9 (bases 1 to 6734)
AUTHORS Arimura,Y., Hinoda,Y., Itoh,F., Takekawa,M., Tsujisaki,M.,
Adachi,M., Imai,K. and Yachi,A.
TITLE cDNA cloning of new protein tyrosine phosphatases in the human
colon
JOURNAL Tumour Biol. 13 (3), 180-186 (1992)
PUBMED 1626183
REFERENCE 10 (bases 1 to 6734)
AUTHORS Yang,Q. and Tonks,N.K.
TITLE Isolation of a cDNA clone encoding a human protein-tyrosine
phosphatase with homology to the cytoskeletal-associated proteins
band 4.1, ezrin, and talin
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 88 (14), 5949-5953 (1991)
PUBMED 1648725
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AK316066.1, BC126117.1,
BC033716.1, DB173093.1, AK096975.1, AL359963.29 and BU624870.1.
On Feb 21, 2009 this sequence version replaced gi:18104985.
Summary: The protein encoded by this gene is a member of the
protein tyrosine phosphatase (PTP) family. PTPs are known to be
signaling molecules that regulate a variety of cellular processes
including cell growth, differentiation, mitotic cycle, and
oncogenic transformation. This protein contains a C-terminal PTP
domain and an N-terminal domain homologous to the band 4.1
superfamily of cytoskeletal-associated proteins. P97, a cell cycle
regulator involved in a variety of membrane related functions, has
been shown to be a substrate of this PTP. This PTP was also found
to interact with, and be regulated by adaptor protein 14-3-3 beta.
Several alternatively spliced transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq, Feb 2009].
Transcript Variant: This variant (1) encodes the longest isoform
(1).
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
CDS exon combination :: M64572.1, BC126117.1 [ECO:0000331]
RNAseq introns :: mixed/partial sample support ERS025081,
ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-1113 AK316066.1 1-1113
1114-3432 BC126117.1 1024-3342
3433-4174 BC033716.1 1459-2200
4175-4512 DB173093.1 253-590
4513-4996 AK096975.1 196-679
4997-5036 AL359963.29 93827-93866 c
5037-6711 AK096975.1 702-2376
6712-6734 BU624870.1 1-23 c
FEATURES Location/Qualifiers
source 1..6734
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="9q31"
gene 1..6734
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/note="protein tyrosine phosphatase, non-receptor type 3"
/db_xref="GeneID:5774"
/db_xref="HGNC:9655"
/db_xref="MIM:176877"
exon 1..95
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
exon 96..250
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(105)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200634188"
CDS 113..2854
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/EC_number="3.1.3.48"
/note="isoform 1 is encoded by transcript variant 1;
cytoskeletal-associated protein tyrosine phosphatase;
tyrosine-protein phosphatase non-receptor type 3;
protein-tyrosine phosphatase H1"
/codon_start=1
/product="tyrosine-protein phosphatase non-receptor type 3
isoform 1"
/protein_id="NP_002820.3"
/db_xref="GI:223941876"
/db_xref="CCDS:CCDS6776.1"
/db_xref="GeneID:5774"
/db_xref="HGNC:9655"
/db_xref="MIM:176877"
/translation="
MTSRLRALGGRINNIRTSELPKEKTRSEVICSIHFLDGVVQTFKVTKQDTGQVLLDMVHNHLGVTEKEYFGLQHDDDSVDSPRWLEASKAIRKQLKGGFPCTLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFLTKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHSGRDLHNLDLMIGIASAGVAVYRKYICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTEDASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLDPS
"
misc_feature 203..778
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/note="Band 4.1 homologues; Region: B41; smart00295"
/db_xref="CDD:197635"
misc_feature 209..445
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/note="FERM N-terminal domain; Region: FERM_N; pfam09379"
/db_xref="CDD:204220"
misc_feature 461..778
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/note="FERM central domain; Region: FERM_M; pfam00373"
/db_xref="CDD:201187"
misc_feature 758..1036
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/note="FERM_C domain; Region: FERM_C; cd00836"
/db_xref="CDD:176273"
misc_feature order(770..793,800..823,827..847,875..880,887..898,
911..931,959..973,998..1024)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/note="PH/PTB-like core; other site"
/db_xref="CDD:176273"
misc_feature order(884..886,890..895,899..907,929..931,1004..1006,
1016..1018,1025..1027)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/note="peptide binding site [polypeptide binding]; other
site"
/db_xref="CDD:176273"
misc_feature 995..997
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/note="lipid binding site [chemical binding];
lipid-binding site"
/db_xref="CDD:176273"
misc_feature 1187..1189
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(P26045.2); phosphorylation site"
misc_feature 1211..1213
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(P26045.2); phosphorylation site"
misc_feature 1238..1240
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine; propagated from
UniProtKB/Swiss-Prot (P26045.2); phosphorylation site"
misc_feature 1253..1255
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(P26045.2); phosphorylation site"
misc_feature 1634..1897
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/note="PDZ domain found in a variety of Eumetazoan
signaling molecules, often in tandem arrangements. May be
responsible for specific protein-protein interactions, as
most PDZ domains bind C-terminal polypeptides, and binding
to internal (non-C-terminal)...; Region: PDZ_signaling;
cd00992"
/db_xref="CDD:29049"
misc_feature order(1670..1681,1685..1687,1835..1840,1847..1852)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/note="protein binding site [polypeptide binding]; other
site"
/db_xref="CDD:29049"
misc_feature 2057..2812
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/note="Protein tyrosine phosphatase, catalytic domain;
Region: PTPc; smart00194"
/db_xref="CDD:197567"
misc_feature 2126..2809
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/note="Protein tyrosine phosphatases (PTP) catalyze the
dephosphorylation of phosphotyrosine peptides; they
regulate phosphotyrosine levels in signal transduction
pathways. The depth of the active site cleft renders the
enzyme specific for phosphorylated Tyr; Region: PTPc;
cd00047"
/db_xref="CDD:28929"
misc_feature order(2543..2545,2633..2638,2645..2647,2654..2659)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/note="active site"
/db_xref="CDD:28929"
misc_feature 2636..2656
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (P26045.2);
Region: Substrate binding (By similarity)"
variation complement(122)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="c"
/db_xref="dbSNP:371966999"
variation complement(128)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:147740778"
variation complement(158)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200407136"
variation complement(166)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:145689613"
variation complement(226)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199740191"
variation complement(233)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:374221054"
exon 251..358
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(278)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372676217"
variation complement(316)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:150949930"
variation complement(334)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370731089"
variation complement(340)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:376106536"
variation complement(341)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:35285139"
variation complement(346)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:35279031"
exon 359..401
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(360)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:150709588"
variation complement(380)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:3793524"
variation complement(395)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="t"
/db_xref="dbSNP:141057944"
exon 402..480
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(436)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:186335053"
variation complement(472)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144399729"
exon 481..525
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(518)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:200472346"
exon 526..578
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(526)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:139361478"
variation complement(535)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:61747620"
variation complement(550)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369609766"
variation complement(562)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:150667989"
variation complement(572)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:138810032"
exon 579..699
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(628)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201824403"
variation complement(630)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370903570"
variation complement(641)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:145013735"
variation complement(670)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:138152923"
variation complement(676)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:148263399"
variation complement(677)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:200331488"
exon 700..787
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation 744
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:193920798"
variation complement(745)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:143196464"
exon 788..876
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(826)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377671421"
variation complement(845)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:149073049"
variation complement(851)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:145005611"
exon 877..940
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(884)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:192064945"
variation complement(888)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199956141"
variation complement(906)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:146954653"
variation complement(930)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:141258824"
exon 941..1113
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(946)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="t"
/db_xref="dbSNP:376928867"
variation complement(987)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:374370776"
variation complement(1004)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:372409514"
variation complement(1014)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:147767465"
variation complement(1016)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368204104"
variation complement(1049)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:374798614"
variation complement(1051)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144167957"
variation complement(1068)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61736875"
variation complement(1100)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370526852"
exon 1114..1248
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(1116)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:376647767"
variation complement(1132)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201919688"
variation complement(1140)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:151104500"
variation complement(1150)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="c"
/db_xref="dbSNP:373387477"
variation complement(1151)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:142980957"
variation complement(1157)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369138815"
variation complement(1183)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:374793150"
variation complement(1224)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:371270540"
variation complement(1245)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148558305"
exon 1249..1425
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(1249)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="g"
/replace="t"
/db_xref="dbSNP:144812815"
variation complement(1250)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="c"
/db_xref="dbSNP:185821807"
variation complement(1264)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:142016536"
variation complement(1266)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201397922"
variation complement(1287)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="g"
/replace="t"
/db_xref="dbSNP:140094288"
variation complement(1300)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:146095498"
variation complement(1333)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:142732873"
variation complement(1337)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:10979858"
variation complement(1339)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372178642"
variation complement(1351)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="g"
/replace="t"
/db_xref="dbSNP:181688303"
variation complement(1353)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368525928"
variation complement(1357)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:138148171"
variation complement(1370)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:374202196"
variation complement(1386)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372151791"
variation complement(1387)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:367948677"
variation complement(1409)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:375004037"
variation complement(1410)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370298571"
variation complement(1417)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:116205878"
variation complement(1418)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200101992"
exon 1426..1612
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(1435)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199620488"
variation complement(1436)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:141809051"
variation complement(1447)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:17803052"
variation complement(1465)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:146992805"
variation complement(1529)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:141350094"
variation complement(1530)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:138707755"
variation complement(1539)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:375545706"
variation complement(1558)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="c"
/db_xref="dbSNP:147174947"
variation complement(1567)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:377369883"
variation complement(1583)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:373058480"
variation complement(1600)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:145875554"
exon 1613..1690
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(1616)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372363344"
variation complement(1618)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="t"
/db_xref="dbSNP:368144041"
variation complement(1638)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:113237352"
variation complement(1640)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="g"
/replace="t"
/db_xref="dbSNP:376855050"
variation complement(1645)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="c"
/db_xref="dbSNP:371910658"
variation complement(1647)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:189241432"
exon 1691..1747
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(1718)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:183458658"
variation complement(1726)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149023035"
variation complement(1727)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="c"
/db_xref="dbSNP:372689393"
variation complement(1728)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144915998"
exon 1748..1904
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(1750)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:150061689"
variation complement(1753)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200410469"
variation complement(1775)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:140628740"
variation complement(1806)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:181792746"
variation complement(1810)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:146841512"
variation complement(1817)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:59324117"
variation complement(1831)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:140140279"
variation complement(1845)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:146077461"
variation complement(1851)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201209769"
variation complement(1869)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144304313"
variation complement(1875)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:199759803"
exon 1905..2065
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(1910)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:148505458"
variation complement(1912)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:374405230"
variation complement(1927)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:7859962"
variation complement(1948)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:34302609"
variation complement(1972)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:150353247"
variation complement(1984)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:371992176"
exon 2066..2156
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(2068)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:147437194"
variation complement(2087)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:371372947"
variation complement(2139)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="t"
/db_xref="dbSNP:377718578"
exon 2157..2218
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(2177)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:76416062"
variation complement(2212)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:138839766"
variation complement(2217)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:145864054"
exon 2219..2365
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(2257)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:140802922"
variation complement(2275)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:147976452"
variation complement(2277)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:189256306"
variation complement(2280)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:143462283"
variation complement(2321)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199692080"
variation complement(2344)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148827369"
exon 2366..2494
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(2380)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:146869100"
variation complement(2393)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:375763821"
variation complement(2398)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:2304742"
variation complement(2399)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:10116806"
variation complement(2413)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:373493427"
variation complement(2416)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:146618446"
variation complement(2432)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="t"
/db_xref="dbSNP:150008661"
variation complement(2456)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370019146"
variation complement(2486)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="c"
/db_xref="dbSNP:139321235"
exon 2495..2640
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(2533)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:150855452"
variation complement(2536)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:146486489"
variation complement(2561)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="g"
/replace="t"
/db_xref="dbSNP:371886206"
variation complement(2563)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:367766327"
variation complement(2569)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:140717531"
variation complement(2588)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="t"
/db_xref="dbSNP:375434242"
variation complement(2613)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:374209870"
variation complement(2617)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:371197800"
variation complement(2618)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:147420952"
variation complement(2623)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:142937669"
variation complement(2624)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:138828543"
variation complement(2635)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:368814204"
exon 2641..2776
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(2655)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372894176"
variation complement(2682)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370374314"
variation complement(2744)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201209437"
variation complement(2756)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201640227"
variation complement(2760)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200077324"
variation complement(2767)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="g"
/replace="t"
/db_xref="dbSNP:147200776"
exon 2777..6716
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/inference="alignment:Splign:1.39.8"
variation complement(2793)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:149479153"
variation complement(2803)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:137963642"
variation complement(2833)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:370012185"
variation complement(2842)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:200403602"
variation complement(2844)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:150328766"
variation complement(2858)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:200494712"
variation complement(2861)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377490884"
variation complement(2869)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:374288172"
variation complement(2896)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:138931600"
variation complement(2932)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:371464957"
variation complement(3052)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:150282450"
variation complement(3082)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:180926631"
variation complement(3117)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:189242626"
variation complement(3192)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:140930516"
variation complement(3223)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:185827185"
variation complement(3349)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="g"
/replace="t"
/db_xref="dbSNP:151038868"
variation complement(3402)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:114131793"
STS 3446..4142
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/standard_name="PTPN3_2445"
/db_xref="UniSTS:280941"
variation complement(3511)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="t"
/db_xref="dbSNP:115197904"
variation complement(3534)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:143684539"
variation complement(3639)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:41278397"
variation complement(3646)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:140622120"
variation complement(3666)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:146826909"
variation complement(3804)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144086616"
variation complement(3820)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:139353948"
variation complement(3838)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:145615584"
STS 3867..4006
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/standard_name="RH78381"
/db_xref="UniSTS:38153"
variation complement(3906)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149748563"
STS 3956..4137
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/standard_name="STS-W15441"
/db_xref="UniSTS:82348"
variation complement(4007)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:374631187"
variation complement(4056)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:139439518"
polyA_signal 4153..4158
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
polyA_site 4174
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
variation complement(4516)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:181698971"
variation complement(4541)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:190049858"
variation complement(4546)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:112728642"
variation complement(4663)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:185204780"
variation complement(4671)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:111938473"
variation complement(4673)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:374737737"
variation complement(4704)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:79977262"
STS 4909..5041
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/standard_name="D9S58"
/db_xref="UniSTS:33358"
variation complement(4951)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="g"
/replace="t"
/db_xref="dbSNP:191660985"
variation complement(4952..4971)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace=""
/replace="tgtgtgtgtgtgtgtgtgtg"
/db_xref="dbSNP:55719272"
variation complement(4957)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace=""
/replace="tgtgtg"
/replace="tgtgtgtgtg"
/db_xref="dbSNP:56934484"
variation complement(5002..5003)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace=""
/replace="tgtgtg"
/db_xref="dbSNP:35223249"
variation complement(5004..5005)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace=""
/replace="gtgtgt"
/db_xref="dbSNP:10627956"
variation complement(5005..5014)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace=""
/replace="gtgtgtgtgt"
/db_xref="dbSNP:72205265"
variation complement(5007..5014)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace=""
/replace="gtgtgtgt"
/db_xref="dbSNP:368150329"
variation complement(5013..5014)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace=""
/replace="gt"
/db_xref="dbSNP:72107370"
variation complement(5097)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:116604074"
variation complement(5206)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:188762071"
variation complement(5376)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:183693786"
variation complement(5409)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:78043549"
variation complement(5411)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="g"
/replace="t"
/db_xref="dbSNP:191559276"
variation complement(5439..5440)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace=""
/replace="ca"
/db_xref="dbSNP:201032332"
variation complement(5541)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368512455"
variation complement(5674)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139540788"
variation complement(5686)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace=""
/replace="t"
/db_xref="dbSNP:36043083"
variation complement(5819)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:188734291"
variation complement(5825)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="c"
/db_xref="dbSNP:73525119"
variation complement(5921)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:113826491"
variation complement(5986)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:143204263"
variation complement(6040)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="g"
/replace="t"
/db_xref="dbSNP:75255713"
variation complement(6052)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="g"
/replace="t"
/db_xref="dbSNP:76421318"
variation complement(6055)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="g"
/replace="t"
/db_xref="dbSNP:34740968"
variation complement(6124)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:111487162"
variation complement(6220..6221)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace=""
/replace="g"
/db_xref="dbSNP:34907594"
variation complement(6227)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149641144"
variation complement(6228)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:115259973"
variation complement(6238..6239)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace=""
/replace="t"
/db_xref="dbSNP:35111984"
variation complement(6301)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:184231955"
variation complement(6339)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="g"
/db_xref="dbSNP:193101927"
variation complement(6378)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:138126149"
variation complement(6431)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="c"
/db_xref="dbSNP:188503580"
variation complement(6461)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="c"
/db_xref="dbSNP:145645925"
variation complement(6483)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:11537746"
variation complement(6484)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:183499796"
STS 6489..6611
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/standard_name="D9S1760"
/db_xref="UniSTS:12586"
STS 6492..6670
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/standard_name="D9S1693"
/db_xref="UniSTS:65182"
STS 6492..6664
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/standard_name="RH91146"
/db_xref="UniSTS:88337"
variation complement(6513)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="c"
/replace="t"
/db_xref="dbSNP:189997655"
variation complement(6521)
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61744961"
STS 6559..6671
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/standard_name="A009V09"
/db_xref="UniSTS:77964"
STS 6559..6671
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
/standard_name="G32870"
/db_xref="UniSTS:117449"
polyA_site 6716
/gene="PTPN3"
/gene_synonym="PTP-H1; PTPH1"
ORIGIN
atgctcagacggcggccaggtcgcgccgcgagcgagcttccgcgccgcccgcacgcgcgacctacctgggcgctccgcgcccccggatgctgcaggttattcagcgatagttatgacctcccggttacgtgcgttgggtggaagaattaataatatacgcacctcggagttacccaaagagaaaactcgatcagaagtcatttgcagcatccactttttagatggcgtggtacagacctttaaagttactaaacaagacactggccaggttcttctggatatggtgcacaaccacctgggtgtgactgaaaaggaatattttggtttacagcatgatgacgactccgtggactctcctagatggctggaagcaagcaaagccatcaggaagcagttaaaaggaggtttcccctgtaccctgcattttcgagtaagattttttatacctgatcccaacacactgcagcaagaacaaaccaggcacttgtatttcttacaactgaagatggatatttgcgaaggaaggttaacctgccctcttaactcagcagtggttctagcgtcctatgccgtacaatctcattttggagactataattcttccatacatcatccaggctatctttccgatagtcactttatacccgatcaaaatgaggactttttaacaaaagtcgaatctctgcatgagcagcacagtgggctaaaacaatcagaagcagaatcctgctatatcaacatagcgcggaccctcgacttctatggagtagaactgcacagtggtagggatctgcacaatttagacctaatgattggaattgcttccgcgggtgttgctgtgtaccgaaaatacatttgcacaagtttctatccttgggtgaacattctcaaaatttctttcaaaaggaaaaagttcttcatacatcagcgacagaaacaggctgaatccagggaacatattgtggccttcaacatgctgaattaccgatcttgcaaaaacttgtggaaatcctgtgttgagcaccatacgttctttcaggcaaagaagctactacctcaggaaaagaatgttctgtctcagtactggactatgggctctcggaacaccaaaaagtcggtaaataaccaatattgcaaaaaggtgattggcgggatggtgtggaacccagccatgcggagatccttatcagtggagcacttagaaaccaagagtctgccttctcgttcccctcccattactcccaactggcgaagtcctcggctccggcacgaaatccgaaagccacgccactcttctgcagataaccttgcaaatgaaatgacctacatcacggaaacggaagatgtattttacacgtacaagggctctctggcccctcaagacagcgattctgaagtttctcagaaccgaagcccgcaccaagagagtttatccgagaacaatccggcacaaagctacctgacccagaagtcatccagttctgtgtctccatcttcaaatgctccaggctcctgctcacctgacggcgttgatcagcagctcttagatgacttccacagggtgaccaaagggggctccaccgaggacgccagccagtactactgtgacaagaatgataatggtgacagctacttagtcttgatccgtatcacaccagatgaagatggaaaatttggatttaatcttaagggaggagtggatcaaaagatgcctcttgtggtatcaaggataaacccagagtcacctgcggacacctgcattcctaagctgaacgaaggggatcaaatcgtgttaatcaatggccgggacatctcagaacacacgcatgaccaagtggtgatgttcatcaaagccagccgggagtcccactcacgggagctggccctggtgatcaggaggagagctgtccgctcatttgctgacttcaagtctgaagatgaactgaaccagcttttccccgaagccattttccccatgtgtccggagggtggggacactttggagggatccatggcacagctaaagaagggcctcgaaagcgggacggtgctgatccagtttgagcaactctacagaaaaaagccaggtttggccatcacgtttgcaaagctgcctcaaaatttggacaaaaaccgatataaagatgtgctgccttatgacaccacccgggtattattgcagggaaatgaagattatattaatgcaagttacgtgaacatggaaattcctgctgctaaccttgtgaacaagtacatcgccactcaggggcccctgccgcatacctgtgcacagttttggcaggttgtctgggatcagaagttgtcactcattgtcatgttgacgactctcacagaacgagggcggaccaaatgtcaccagtactggccagatccccccgacgtcatgaaccacggcggctttcacatccagtgtcagtcagaggactgcaccatcgcctatgtgtcccgagaaatgctggtcacaaacacccagaccggggaagaacacacagtgacacatctccagtacgtcgcatggcctgaccacggtgtgcccgatgactcctccgactttctggaatttgtaaactatgtgaggtctctgagagtggacagcgagcccgtcctagttcactgcagtgctggaataggtcgaaccggtgtgttggtcactatggaaacagccatgtgcctaactgagaggaacctgcccatttacccactggatattgtccgaaaaatgcgagaccagcgcgccatgatggtgcagacatcaagccagtacaagtttgtgtgtgaagcgattcttcgtgtgtatgaagaaggtttagtccaaatgctggatcctagttaagacaactgtgaaaaagttcattcctctttcccaagggcatcctccttgaaagaggaggacagacctctctggaagcagcaagaggaaccagtagctgtgggaaaggaatgggcacctctgaacccaggcactttaaacttctatagaaaagatatcgtgtacataggaactggtgtagataagcatgcaattatggcatcatttaggcctgtatttctatggaaagatacaaaaaggatctcagtttggggcctgtcctaatgccttcttccctaacatcaccacacacacccctgtcggcatcctggagcaattgagaccggacacccacagagctgttgtcctcccagcaacaagatggtgtggttatcttgggtcatttggatgttttgtttgtttctgtgtgtcagactgtaagggctgagctttctgtgcttctaggtggagctggaacaattcagattcacccgccctgatgctaaggaaaccctgacgtatgtactagatggcagggcactgggggtcaggctgaaggctgagcaacacctctctgccctccctccctttgtcccatctcccagcgacttccaatattcatgtttctgagaattgtgtccctcttcaggttccctcttggtgcctaacctggattagtaatgtgcattcaggtgaattttcagctgaggctctgagaactggtactctcagtgtgttctggtcatcttgtggcttagttgtagaagcaggtgtgtctcttgcctctgcttgcctcctactgcacactcagcacccaggactggaatcaccgactactgaatctcctacatgtattgctgctacttcaagctcctccacttgaaaccttatgattttcccaaggggagatgggacagtgtcatctaaatattccgaatgtttggccttctgagaaaagagcttctagtaattgaaccatgggaaacccagcttctggagggttggccgtggggctgtgtacatgtgtgtgcccaggggtgagtgtttctcaggattcctaacgattcaaattaccgttgagtatatataaagaatgagtctctgtatggaagaacaaatgtgtgcattcacccccagtcacaatggtctccattgcatttcaaaggagaggatcagactatctgaatataaacacaatctgatgttaatttattctaagaacaccatcattttgattgtcctaaagaattctgcctttgtgaataccgtgttaaatttttttaaatttgtgacaggattgtagcaaattattatttaaggaaaataaattgtgtaaacatttaatgtggtatttttgaacagcggtttttatgtactcagaagaggaagtaaagccaggttcttaatggtatttatagaaaagatgttttcatattataatgcacataaatgaagccattttgatattcagcaaattcggtgccaattgaatagtttgctggtagcaagacggatgaagacctatatgggagattctttatctctagagctagcatatttacttgcatactttgtttcttttccacatggatattttactgctaaatggcagaggtgggagggagatgtcacacagtaccataaccccatattgaaaacaagaaaccaccagaaagtttgcagctaaggggcaggggattcagttcctacgcccactcagcactaactacttgcgggcctggttgcttagaagctctacctctctttcattatctgtaaaatagaaacaatacttaggactttagttggaacatgaggattgaataagatcacgctattcatgtgactttttatcggctagaacagcaacagacactgctgtgggtgagttacttagaaaagtttagttatcagtgattagcccaaaaacacatcagtcaaaaatagaatccactggatttttgtctctctttttagagacagggtctcactgtcgcccaggctggagtacagtggcatgatcattgttcactgcagcctcaaattcctgggctcaagcaatcctcgcacctcagcctcctgagtagccgggactataggcacatgccacctcacctggcttgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtagagacaggatcttgatgtgttgcctaggctggtctcaaactcctggcctcaagtgatcttcccacctcagcctccaaaactgttgggattataggcgtgagccactgtgcccagcctaactgggtttttatgagaggaaaatagaaaatgctcttctagaagagagagaacaagagcacaaaataatctggactcacaaaaattcagcaagctccaagaaagggggatggagggaacgctggcaaaaatttaaatgccattaggatatttagcaagttattactgtttggtaaaaatgcatcatcaccctgtgtgcaaaatgcttgcaaagtagtctaaatgtctttggagatgggtgttttactgcttttttccaaaaacaaattgtttattatggttgcagaaatgcagccattacggtcacataaatttctaaaaagcctaccaaaggttgcaagcagtcttctgccactgggcaggccagcagttcagacccagcgaggttgccaggaacaaatccaggaaatactgggaagaacaagacaagagaattacctaaaagagcaaacaattcaagtaaatcctgtagctattaccacttaaaatccgtagctcaagattcctgtttcaccaccttatacacttaagcaattatacttaagcctttttttagtcctaagtgaagaactacatcagaatcaggataagtattttgcctgggaaatttggctgcatatgaatggagaagacatttacatcctatgttctggcactttctgaaagatctaattaaacatgttgatgtgccaatttaatcaagatgagagatccctgctggtgtcaccctctagaacctgcacttggtgttttgactttccagaagaaaaaaatgcaactttggttagggggcagtggttggatcacacagttgtctttcgtttcctaccacagtaattcatatttaaatatgcttttagattagtgtggatactattgctgctgtgttgctacctgacctttttctggggggggtacctcagaaatgagcatttgagggcaagcgaaaaagccctcttcatcctccagaggcaacaaagaggcagcagaaatggggaaagattgtgagaggcagggcttgggtctagacctggacttaggcaagatatgttgccctcaaccctgagttttcttatatgtaaaaagggaaggttgggctggactagatgaggtcaagatttgccattctgggaggctgatattccagagaatcaaaattaatcctaaaccaaagctttatggctgctacagagacatgtcacatttctgagacttgtcaccaagagtttgtccctcagactttggcgctgttgaatgcaaagacaaggatggccaccttctggttcttgcctgttgtcctcagctgagagcagtctcggtaaaggtggcaaagattctgtgacctcagaccggggaccaaatgcttgggagtctgatggccgggctgggccaccattctcatagctctcattctgtttggagcaaccaaaggatttgtgtgaagttatttggaaaaggaccttaactgagcagtaatcttttttctgtatatttggaatgtttttcattctgacctgttctgtcagtgattctactgaaaaacaatttaatcaatataaaaatgttcaagctatgcaacactgtaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:5774 -> Molecular function: GO:0001784 [phosphotyrosine binding] evidence: IPI
GeneID:5774 -> Molecular function: GO:0004725 [protein tyrosine phosphatase activity] evidence: IDA
GeneID:5774 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:5774 -> Molecular function: GO:0008092 [cytoskeletal protein binding] evidence: IEA
GeneID:5774 -> Molecular function: GO:0051117 [ATPase binding] evidence: IPI
GeneID:5774 -> Biological process: GO:0006470 [protein dephosphorylation] evidence: IDA
GeneID:5774 -> Biological process: GO:0035335 [peptidyl-tyrosine dephosphorylation] evidence: IDA
GeneID:5774 -> Biological process: GO:0035335 [peptidyl-tyrosine dephosphorylation] evidence: TAS
GeneID:5774 -> Biological process: GO:0045930 [negative regulation of mitotic cell cycle] evidence: IDA
GeneID:5774 -> Biological process: GO:0051045 [negative regulation of membrane protein ectodomain proteolysis] evidence: IMP
GeneID:5774 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:5774 -> Cellular component: GO:0005856 [cytoskeleton] evidence: IEA
GeneID:5774 -> Cellular component: GO:0009898 [internal side of plasma membrane] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_002820 -> EC 3.1.3.48
by
@meso_cacase at
DBCLS
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