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2024-04-25 12:37:19, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_002811               1686 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens proteasome (prosome, macropain) 26S subunit,
            non-ATPase, 7 (PSMD7), mRNA.
ACCESSION   NM_002811
VERSION     NM_002811.4  GI:325652102
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1686)
  AUTHORS   Niu,Z., Lei,R., Shi,J., Wang,D., Shou,W., Wang,Z., Wang,Y., Wang,Z.
            and Huang,W.
  TITLE     A polymorphism rs17336700 in the PSMD7 gene is associated with
            ankylosing spondylitis in Chinese subjects
  JOURNAL   Ann. Rheum. Dis. 70 (4), 706-707 (2011)
   PUBMED   20643764
  REMARK    GeneRIF: SNP rs17336700 of a non-MHC ubiquitin-proteasome subunit
            PSMD7 is significantly associated with ankylosing spondylitis in
            Chinese population and the mRNA level of the PSMD7 gene in liver
            tissue increased when the rs17336700 C allele was present.
            GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   2  (bases 1 to 1686)
  AUTHORS   Dastani,Z., Pajukanta,P., Marcil,M., Rudzicz,N., Ruel,I.,
            Bailey,S.D., Lee,J.C., Lemire,M., Faith,J., Platko,J., Rioux,J.,
            Hudson,T.J., Gaudet,D., Engert,J.C. and Genest,J.
  TITLE     Fine mapping and association studies of a high-density lipoprotein
            cholesterol linkage region on chromosome 16 in French-Canadian
            subjects
  JOURNAL   Eur. J. Hum. Genet. 18 (3), 342-347 (2010)
   PUBMED   19844255
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   3  (bases 1 to 1686)
  AUTHORS   Sanches,M., Alves,B.S., Zanchin,N.I. and Guimaraes,B.G.
  TITLE     The crystal structure of the human Mov34 MPN domain reveals a
            metal-free dimer
  JOURNAL   J. Mol. Biol. 370 (5), 846-855 (2007)
   PUBMED   17559875
  REMARK    GeneRIF: although the MPN domain of Mov34 shows a typical
            metalloprotease fold, it is unable to coordinate a metal ion.
REFERENCE   4  (bases 1 to 1686)
  AUTHORS   Lamesch,P., Li,N., Milstein,S., Fan,C., Hao,T., Szabo,G., Hu,Z.,
            Venkatesan,K., Bethel,G., Martin,P., Rogers,J., Lawlor,S.,
            McLaren,S., Dricot,A., Borick,H., Cusick,M.E., Vandenhaute,J.,
            Dunham,I., Hill,D.E. and Vidal,M.
  TITLE     hORFeome v3.1: a resource of human open reading frames representing
            over 10,000 human genes
  JOURNAL   Genomics 89 (3), 307-315 (2007)
   PUBMED   17207965
REFERENCE   5  (bases 1 to 1686)
  AUTHORS   Huang,W., Pi,L., Liang,W., Xu,B., Wang,H., Cai,R. and Huang,H.
  TITLE     The proteolytic function of the Arabidopsis 26S proteasome is
            required for specifying leaf adaxial identity
  JOURNAL   Plant Cell 18 (10), 2479-2492 (2006)
   PUBMED   17028202
REFERENCE   6  (bases 1 to 1686)
  AUTHORS   Seeger,M., Ferrell,K., Frank,R. and Dubiel,W.
  TITLE     HIV-1 tat inhibits the 20 S proteasome and its 11 S
            regulator-mediated activation
  JOURNAL   J. Biol. Chem. 272 (13), 8145-8148 (1997)
   PUBMED   9079628
REFERENCE   7  (bases 1 to 1686)
  AUTHORS   Coux,O., Tanaka,K. and Goldberg,A.L.
  TITLE     Structure and functions of the 20S and 26S proteasomes
  JOURNAL   Annu. Rev. Biochem. 65, 801-847 (1996)
   PUBMED   8811196
  REMARK    Review article
REFERENCE   8  (bases 1 to 1686)
  AUTHORS   Tsurumi,C., DeMartino,G.N., Slaughter,C.A., Shimbara,N. and
            Tanaka,K.
  TITLE     cDNA cloning of p40, a regulatory subunit of the human 26S
            proteasome, and a homolog of the Mov-34 gene product
  JOURNAL   Biochem. Biophys. Res. Commun. 210 (2), 600-608 (1995)
   PUBMED   7755639
REFERENCE   9  (bases 1 to 1686)
  AUTHORS   Gridley,T., Gray,D.A., Orr-Weaver,T., Soriano,P., Barton,D.E.,
            Francke,U. and Jaenisch,R.
  TITLE     Molecular analysis of the Mov 34 mutation: transcript disrupted by
            proviral integration in mice is conserved in Drosophila
  JOURNAL   Development 109 (1), 235-242 (1990)
   PUBMED   2209467
REFERENCE   10 (bases 1 to 1686)
  AUTHORS   Winkelmann,D.A. and Kahan,L.
  TITLE     Immunochemical accessibility of ribosomal protein S4 in the 30 S
            ribosome. The interaction of S4 with S5 and S12
  JOURNAL   J. Mol. Biol. 165 (2), 357-374 (1983)
   PUBMED   6188845
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BU601564.1, BC000338.2,
            BC012606.1 and CA429667.1.
            On Mar 10, 2011 this sequence version replaced gi:34335279.
            
            Summary: The 26S proteasome is a multicatalytic proteinase complex
            with a highly ordered structure composed of 2 complexes, a 20S core
            and a 19S regulator. The 20S core is composed of 4 rings of 28
            non-identical subunits; 2 rings are composed of 7 alpha subunits
            and 2 rings are composed of 7 beta subunits. The 19S regulator is
            composed of a base, which contains 6 ATPase subunits and 2
            non-ATPase subunits, and a lid, which contains up to 10 non-ATPase
            subunits. Proteasomes are distributed throughout eukaryotic cells
            at a high concentration and cleave peptides in an
            ATP/ubiquitin-dependent process in a non-lysosomal pathway. An
            essential function of a modified proteasome, the immunoproteasome,
            is the processing of class I MHC peptides. This gene encodes a
            non-ATPase subunit of the 19S regulator. A pseudogene has been
            identified on chromosome 17. [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BU601564.1, D50063.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025082 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-13                BU601564.1         4-16
            14-1087             BC000338.2         1-1074
            1088-1164           BC012606.1         1069-1145
            1165-1686           CA429667.1         1-522               c
FEATURES             Location/Qualifiers
     source          1..1686
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q22.3"
     gene            1..1686
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /note="proteasome (prosome, macropain) 26S subunit,
                     non-ATPase, 7"
                     /db_xref="GeneID:5713"
                     /db_xref="HGNC:9565"
                     /db_xref="HPRD:01147"
                     /db_xref="MIM:157970"
     exon            1..214
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /inference="alignment:Splign:1.39.8"
     variation       42
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:192906661"
     variation       49
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144668882"
     misc_feature    60..62
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /note="upstream in-frame stop codon"
     variation       77
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:79151396"
     variation       79
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368923669"
     variation       90
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372447684"
     variation       104
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:376680205"
     variation       106
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:369694607"
     variation       112
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373670617"
     variation       119
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377009439"
     variation       122
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369200544"
     variation       124
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:373517773"
     variation       127
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377461997"
     CDS             141..1115
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /note="Mov34 homolog; proteasome (prosome, macropain) 26S
                     subunit, non-ATPase, 7 (Mov34 homolog); proteasome subunit
                     p40; 26S proteasome regulatory subunit S12; Moloney
                     leukemia virus-34 proviral integration; 26S proteasome
                     regulatory subunit rpn8"
                     /codon_start=1
                     /product="26S proteasome non-ATPase regulatory subunit 7"
                     /protein_id="NP_002802.2"
                     /db_xref="GI:25777615"
                     /db_xref="CCDS:CCDS10910.1"
                     /db_xref="GeneID:5713"
                     /db_xref="HGNC:9565"
                     /db_xref="HPRD:01147"
                     /db_xref="MIM:157970"
                     /translation="
MPELAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNSVLVIIDVKPKDLGLPTEAYISVEEVHDDGTPTSKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVATGKLPINHQIIYQLQDVFNLLPDVSLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEKKEGQEKEESKKDRKEDKEKDKDKEKSDVKKEEKKEKK
"
     misc_feature    201..995
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /note="Mpr1p, Pad1p N-terminal (MPN) domains without
                     catalytic isopeptidase activity, found in 19S proteasomal
                     subunits Rpn7 and Rpn8; Region: MPN_RPN7_8; cd08062"
                     /db_xref="CDD:163693"
     misc_feature    750..752
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-acetyllysine; propagated from
                     UniProtKB/Swiss-Prot (P51665.2); acetylation site"
     misc_feature    780..782
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N6-acetyllysine; propagated from
                     UniProtKB/Swiss-Prot (P51665.2); acetylation site"
     variation       176
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146489140"
     variation       182
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:140870371"
     variation       188
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:144697182"
     variation       204
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:367911415"
     exon            215..306
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /inference="alignment:Splign:1.39.8"
     variation       218
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140080000"
     variation       241
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:189793049"
     variation       278
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201703343"
     exon            307..399
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /inference="alignment:Splign:1.39.8"
     variation       356
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150308557"
     variation       395
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:138324633"
     exon            400..497
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /inference="alignment:Splign:1.39.8"
     variation       445
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200662962"
     variation       446
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200193234"
     exon            498..578
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /inference="alignment:Splign:1.39.8"
     variation       539
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:149640570"
     variation       550
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200238995"
     exon            579..670
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /inference="alignment:Splign:1.39.8"
     variation       596
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146675242"
     variation       611
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374113475"
     variation       616
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:139257842"
     exon            671..1670
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /inference="alignment:Splign:1.39.8"
     variation       727
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114830828"
     variation       751
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143079395"
     variation       785
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368732606"
     variation       786
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:115842956"
     variation       804
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147477445"
     variation       836
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372322626"
     variation       837
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140014748"
     variation       844
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201421180"
     variation       852
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:188477810"
     variation       869
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141835646"
     variation       876
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:373688812"
     variation       920
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376923910"
     variation       932
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369506812"
     variation       944
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150615969"
     variation       987
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200912734"
     variation       1027
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139178964"
     variation       1030
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:15263"
     variation       1039
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374062620"
     variation       1084
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:7603"
     variation       1090
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199587020"
     variation       1094..1095
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3208882"
     variation       1097
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3208888"
     variation       1246
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139999979"
     variation       1281
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143705113"
     variation       1548
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1057013"
     variation       1571
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1057012"
     polyA_signal    1650..1655
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
     polyA_site      1670
                     /gene="PSMD7"
                     /gene_synonym="MOV34; P40; Rpn8; S12"
ORIGIN      
gggagcggaagaaggaggccgcgcgagggctgacgaaccggaagaagaggaactgggcctgaaagggtaccggtgaccgctactgctgccggtgtttgcgtgtggcagggagccaggcctggcgagcggggtgtgtcgcgatgccggagctggcagtgcagaaggtggtggtccaccccctggtgctgctcagtgtggtggatcatttcaaccgaatcggcaaggttggaaaccagaagcgtgttgttggtgtgcttttggggtcatggcaaaagaaagtacttgatgtatcgaacagttttgcagttccttttgatgaagatgacaaagacgattctgtatggtttttagaccatgattatttggaaaacatgtatggaatgtttaagaaagtcaatgccagggaaagaatagttggctggtaccacacaggccctaaactacacaagaatgacattgccatcaacgaactcatgaaaagatactgtcctaattccgtattggtcatcattgatgtgaagccgaaggacctagggctgcctacagaagcgtacatttcagtggaagaagtccatgatgatggaactccaacctcgaaaacatttgaacacgtgaccagtgaaattggagcagaggaagctgaggaagttggagttgaacacttgttacgagatatcaaagacacgacggtgggcactctgtcccagcggatcacaaaccaggtccatggtttgaagggactgaactccaagcttctggatatcaggagctacctggaaaaagtcgccacaggcaagctgcccatcaaccaccagatcatctaccagctgcaggacgtcttcaacctgctgccagatgtcagcctgcaggagttcgtcaaggccttttacctgaagaccaatgaccagatggtggtagtgtacttggcctcgctgatccgttccgtggtcgccctgcacaacctcatcaacaacaagattgccaaccgggatgcagagaagaaagaagggcaggagaaagaagagagcaaaaaggataggaaagaggacaaggagaaagataaagataaggaaaagagtgatgtaaagaaagaggagaaaaaggagaaaaagtaaaacatgtattaaatagcttttttaatttgtaaattaaaatcttacaaactaaatcagtgtgctgctagagggttctttttcacttgacatgcttattagaaagctgacccaacaagagctctctgcctccggtcactcttgctgtggtgctacgtggaagtgaatggagactgatctcaaatctgaactgcagctttcgctgctgtgagttggggatatgatagtcagctcaggcttcagattgtatgagaaaaatgaagagaagtcaacaaatattttggtactcttcattcatttatctctaaaaccaggagttgaattttcctcatcttgaaagactcttggggtctgtttctggtattttacaaaattgctaagtggaatgcatgaattgcattatgttctctggtaacacgtagagttcagacccttctgaactctgttgataataccacaccatgttctggacccatagctctggcatcctcaggggttgtgatccagctccatatattgtttaccttcaaagatacaattaaatggcttgatttttaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:5713 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:5713 -> Biological process: GO:0000082 [G1/S transition of mitotic cell cycle] evidence: TAS
            GeneID:5713 -> Biological process: GO:0000209 [protein polyubiquitination] evidence: TAS
            GeneID:5713 -> Biological process: GO:0000278 [mitotic cell cycle] evidence: TAS
            GeneID:5713 -> Biological process: GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] evidence: TAS
            GeneID:5713 -> Biological process: GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent] evidence: TAS
            GeneID:5713 -> Biological process: GO:0006521 [regulation of cellular amino acid metabolic process] evidence: TAS
            GeneID:5713 -> Biological process: GO:0006915 [apoptotic process] evidence: TAS
            GeneID:5713 -> Biological process: GO:0006977 [DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest] evidence: TAS
            GeneID:5713 -> Biological process: GO:0010467 [gene expression] evidence: TAS
            GeneID:5713 -> Biological process: GO:0016032 [viral process] evidence: TAS
            GeneID:5713 -> Biological process: GO:0016070 [RNA metabolic process] evidence: TAS
            GeneID:5713 -> Biological process: GO:0016071 [mRNA metabolic process] evidence: TAS
            GeneID:5713 -> Biological process: GO:0031145 [anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process] evidence: TAS
            GeneID:5713 -> Biological process: GO:0034641 [cellular nitrogen compound metabolic process] evidence: TAS
            GeneID:5713 -> Biological process: GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I] evidence: TAS
            GeneID:5713 -> Biological process: GO:0042981 [regulation of apoptotic process] evidence: TAS
            GeneID:5713 -> Biological process: GO:0043066 [negative regulation of apoptotic process] evidence: TAS
            GeneID:5713 -> Biological process: GO:0044281 [small molecule metabolic process] evidence: TAS
            GeneID:5713 -> Biological process: GO:0051436 [negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle] evidence: TAS
            GeneID:5713 -> Biological process: GO:0051437 [positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle] evidence: TAS
            GeneID:5713 -> Biological process: GO:0051439 [regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle] evidence: TAS
            GeneID:5713 -> Cellular component: GO:0000502 [proteasome complex] evidence: TAS
            GeneID:5713 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
            GeneID:5713 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:5713 -> Cellular component: GO:0005838 [proteasome regulatory particle] evidence: TAS

by @meso_cacase at DBCLS
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