Home |
Help |
Advanced search
2024-04-25 21:22:05, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_002738 8014 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens protein kinase C, beta (PRKCB), transcript variant 2,
mRNA.
ACCESSION NM_002738
VERSION NM_002738.6 GI:197100031
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 8014)
AUTHORS Oleksyn,D., Pulvino,M., Zhao,J., Misra,R., Vosoughi,A., Jenks,S.,
Tipton,C., Lund,F., Schwartz,G., Goldman,B., Mohan,C., Mehta,K.,
Mehta,M., Leitgets,M., Sanz,I. and Chen,L.
TITLE Protein kinase Cbeta is required for lupus development in Sle mice
JOURNAL Arthritis Rheum. 65 (4), 1022-1031 (2013)
PUBMED 23280626
REMARK GeneRIF: Inhibition of PKCbeta enhanced apoptosis of human
autoreactive B cells.
REFERENCE 2 (bases 1 to 8014)
AUTHORS Posti,J.P., Salo,P., Ruohonen,S., Valve,L., Muszkat,M.,
Sofowora,G.G., Kurnik,D., Stein,C.M., Perola,M., Scheinin,M. and
Snapir,A.
TITLE A polymorphism in the protein kinase C gene PRKCB is associated
with alpha2-adrenoceptor-mediated vasoconstriction
JOURNAL Pharmacogenet. Genomics 23 (3), 127-134 (2013)
PUBMED 23337848
REMARK GeneRIF: Genetic variation in protein kinase C type beta may
contribute toward the interindividual variation in DHV constriction
responses to alpha2-AR activation by the agonist dexmedetomidine
REFERENCE 3 (bases 1 to 8014)
AUTHORS Lutzny,G., Kocher,T., Schmidt-Supprian,M., Rudelius,M.,
Klein-Hitpass,L., Finch,A.J., Durig,J., Wagner,M., Haferlach,C.,
Kohlmann,A., Schnittger,S., Seifert,M., Wanninger,S., Zaborsky,N.,
Oostendorp,R., Ruland,J., Leitges,M., Kuhnt,T., Schafer,Y.,
Lampl,B., Peschel,C., Egle,A. and Ringshausen,I.
TITLE Protein kinase c-beta-dependent activation of NF-kappaB in stromal
cells is indispensable for the survival of chronic lymphocytic
leukemia B cells in vivo
JOURNAL Cancer Cell 23 (1), 77-92 (2013)
PUBMED 23328482
REMARK GeneRIF: The expression of protein kinase C (PKC)-betaII and the
subsequent activation of NF-kappaB in bone marrow stromal cells are
prerequisites to support the survival of malignant B cells.
REFERENCE 4 (bases 1 to 8014)
AUTHORS Tabit,C.E., Shenouda,S.M., Holbrook,M., Fetterman,J.L., Kiani,S.,
Frame,A.A., Kluge,M.A., Held,A., Dohadwala,M.M., Gokce,N.,
Farb,M.G., Rosenzweig,J., Ruderman,N., Vita,J.A. and Hamburg,N.M.
TITLE Protein kinase C-beta contributes to impaired endothelial insulin
signaling in humans with diabetes mellitus
JOURNAL Circulation 127 (1), 86-95 (2013)
PUBMED 23204109
REMARK GeneRIF: Our findings implicate PKCbeta activity in endothelial
insulin resistance.
REFERENCE 5 (bases 1 to 8014)
AUTHORS Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee
JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K,
Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z,
Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN,
Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A,
Boucher G, Brand S, Buning C, Cohain A, Cichon S, D'Amato M, De
Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson
LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas
J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH,
Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees
CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W,
Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M,
Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber
S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M,
Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier
RJ, Zeissig S, Zhang B, Zhang CK, Zhao H, Silverberg MS, Annese V,
Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD,
Schadt EE, Daly MJ, Franke A, Parkes M, Vermeire S, Barrett JC and
Cho JH.
CONSRTM International IBD Genetics Consortium (IIBDGC)
TITLE Host-microbe interactions have shaped the genetic architecture of
inflammatory bowel disease
JOURNAL Nature 491 (7422), 119-124 (2012)
PUBMED 23128233
REFERENCE 6 (bases 1 to 8014)
AUTHORS Obeid,L.M., Blobe,G.C., Karolak,L.A. and Hannun,Y.A.
TITLE Cloning and characterization of the major promoter of the human
protein kinase C beta gene. Regulation by phorbol esters
JOURNAL J. Biol. Chem. 267 (29), 20804-20810 (1992)
PUBMED 1400396
REFERENCE 7 (bases 1 to 8014)
AUTHORS Goode,N., Hughes,K., Woodgett,J.R. and Parker,P.J.
TITLE Differential regulation of glycogen synthase kinase-3 beta by
protein kinase C isotypes
JOURNAL J. Biol. Chem. 267 (24), 16878-16882 (1992)
PUBMED 1324914
REFERENCE 8 (bases 1 to 8014)
AUTHORS Moss,S.J., Doherty,C.A. and Huganir,R.L.
TITLE Identification of the cAMP-dependent protein kinase and protein
kinase C phosphorylation sites within the major intracellular
domains of the beta 1, gamma 2S, and gamma 2L subunits of the
gamma-aminobutyric acid type A receptor
JOURNAL J. Biol. Chem. 267 (20), 14470-14476 (1992)
PUBMED 1321150
REFERENCE 9 (bases 1 to 8014)
AUTHORS Devalia,V., Thomas,N.S., Roberts,P.J., Jones,H.M. and Linch,D.C.
TITLE Down-regulation of human protein kinase C alpha is associated with
terminal neutrophil differentiation
JOURNAL Blood 80 (1), 68-76 (1992)
PUBMED 1611098
REFERENCE 10 (bases 1 to 8014)
AUTHORS Niino,Y.S., Ohno,S. and Suzuki,K.
TITLE Positive and negative regulation of the transcription of the human
protein kinase C beta gene
JOURNAL J. Biol. Chem. 267 (9), 6158-6163 (1992)
PUBMED 1556124
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DB456157.1, BC036472.1 and
AC130448.2.
This sequence is a reference standard in the RefSeqGene project.
On Aug 20, 2008 this sequence version replaced gi:47157320.
Summary: Protein kinase C (PKC) is a family of serine- and
threonine-specific protein kinases that can be activated by calcium
and second messenger diacylglycerol. PKC family members
phosphorylate a wide variety of protein targets and are known to be
involved in diverse cellular signaling pathways. PKC family members
also serve as major receptors for phorbol esters, a class of tumor
promoters. Each member of the PKC family has a specific expression
profile and is believed to play a distinct role in cells. The
protein encoded by this gene is one of the PKC family members. This
protein kinase has been reported to be involved in many different
cellular functions, such as B cell activation, apoptosis induction,
endothelial cell proliferation, and intestinal sugar absorption.
Studies in mice also suggest that this kinase may also regulate
neuronal functions and correlate fear-induced conflict behavior
after stress. Alternatively spliced transcript variants encoding
distinct isoforms have been reported. [provided by RefSeq, Jul
2008].
Transcript Variant: This variant (2) represents the longer
transcript and encodes the longer isoform (2).
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data because no single transcript was available
for the full length of the gene. The extent of this transcript is
supported by transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: X07109.1, BC036472.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025082, ERS025084 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-45 DB456157.1 1-45
46-2236 BC036472.1 6-2196
2237-8014 AC130448.2 28957-34734 c
FEATURES Location/Qualifiers
source 1..8014
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16p11.2"
gene 1..8014
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="protein kinase C, beta"
/db_xref="GeneID:5579"
/db_xref="HGNC:9395"
/db_xref="HPRD:01499"
/db_xref="MIM:176970"
exon 1..370
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 28
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371723231"
misc_feature 30..32
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="upstream in-frame stop codon"
variation 173
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:188342168"
variation 189
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374642745"
CDS 198..2219
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/EC_number="2.7.11.13"
/note="isoform 2 is encoded by transcript variant 2;
protein kinase C, beta 1 polypeptide; protein kinase C
beta type; PKC-B"
/codon_start=1
/product="protein kinase C beta type isoform 2"
/protein_id="NP_002729.2"
/db_xref="GI:20127450"
/db_xref="CCDS:CCDS10619.1"
/db_xref="GeneID:5579"
/db_xref="HGNC:9395"
/db_xref="HPRD:01499"
/db_xref="MIM:176970"
/translation="
MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFSFVNSEFLKPEVKS
"
misc_feature 243..245
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:01499"
misc_feature 246..248
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:01499"
misc_feature 306..455
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="Protein kinase C conserved region 1 (C1) .
Cysteine-rich zinc binding domain. Some members of this
domain family bind phorbol esters and diacylglycerol, some
are reported to bind RasGTP. May occur in tandem
arrangement. Diacylglycerol (DAG) is a second...; Region:
C1; cd00029"
/db_xref="CDD:28911"
misc_feature order(306..308,345..347,354..356,396..398,405..407,
420..422,429..431,453..455)
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="zinc binding sites [ion binding]; other site"
/db_xref="CDD:28911"
misc_feature order(327..329,336..341,366..386)
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="putative DAG/PE binding site; other site"
/db_xref="CDD:28911"
misc_feature order(336..338,342..344)
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="putative RAS interaction site [polypeptide
binding]; other site"
/db_xref="CDD:28911"
misc_feature 501..650
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="Protein kinase C conserved region 1 (C1) .
Cysteine-rich zinc binding domain. Some members of this
domain family bind phorbol esters and diacylglycerol, some
are reported to bind RasGTP. May occur in tandem
arrangement. Diacylglycerol (DAG) is a second...; Region:
C1; cd00029"
/db_xref="CDD:28911"
misc_feature order(501..503,540..542,549..551,591..593,600..602,
615..617,624..626,648..650)
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="zinc binding sites [ion binding]; other site"
/db_xref="CDD:28911"
misc_feature order(522..524,531..536,561..581)
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="putative DAG/PE binding site; other site"
/db_xref="CDD:28911"
misc_feature order(531..533,537..539)
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="putative RAS interaction site [polypeptide
binding]; other site"
/db_xref="CDD:28911"
misc_feature 672..1064
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="C2 domain in Protein Kinase C (PKC) alpha and
gamma; Region: C2_PKC_alpha_gamma; cd04026"
/db_xref="CDD:175992"
misc_feature order(756..758,774..776,933..935,939..941,957..959)
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="Ca2+ binding site [ion binding]; other site"
/db_xref="CDD:175992"
misc_feature 1218..2186
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="Catalytic domain of the Protein Serine/Threonine
Kinase, Classical Protein Kinase C; Region: STKc_cPKC;
cd05587"
/db_xref="CDD:173678"
misc_feature 1221..1997
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="Serine/Threonine protein kinases, catalytic domain;
Region: S_TKc; smart00220"
/db_xref="CDD:197582"
misc_feature order(1239..1253,1263..1265,1302..1304,1308..1310,
1407..1409,1455..1460,1464..1466,1476..1478,1482..1484,
1593..1595,1599..1601,1605..1610,1614..1616,1644..1649,
1656..1658,1698..1715,1794..1796,1812..1814,1821..1823)
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="active site"
/db_xref="CDD:173678"
misc_feature order(1239..1244,1254..1256,1263..1265,1302..1304,
1308..1310,1407..1409,1455..1466,1605..1610,1614..1616,
1644..1649)
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:173678"
misc_feature order(1251..1253,1476..1478,1482..1484,1593..1595,
1599..1601,1605..1607,1656..1658,1698..1715,1794..1796,
1812..1814,1821..1823)
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:173678"
misc_feature 1644..1715
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="activation loop (A-loop); other site"
/db_xref="CDD:173678"
misc_feature 1695..1697
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2118..2120
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="turn motif phosphorylation site [posttranslational
modification]; other site"
/db_xref="CDD:173678"
misc_feature 2118..2120
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
misc_feature 2163..2180
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/note="hydrophobic motif (HM); other site"
/db_xref="CDD:173678"
variation 211
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/db_xref="dbSNP:201366670"
variation 223
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/db_xref="dbSNP:368093414"
variation 232
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="t"
/db_xref="dbSNP:370984906"
variation 262
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200442462"
variation 276
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/db_xref="dbSNP:75964872"
variation 284
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:146177740"
variation 359
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:115667450"
exon 371..402
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
exon 403..485
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 406
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="g"
/replace="t"
/db_xref="dbSNP:370311602"
variation 461
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:115750906"
variation 462
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371650623"
variation 482
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371087215"
exon 486..597
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 496
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="g"
/replace="t"
/db_xref="dbSNP:3729895"
variation 521
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:116749372"
variation 536
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377143661"
exon 598..726
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 656
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:372836893"
variation 690
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:199648786"
variation 710
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:115645964"
variation 711
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200811816"
variation 719
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:116345778"
exon 727..883
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 803
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:3729896"
exon 884..1018
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 885
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:200005518"
variation 899
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:114093019"
variation 911
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:17847891"
exon 1019..1115
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 1046
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:17847884"
variation 1078
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199901715"
variation 1090
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:147975795"
variation 1103
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:115598469"
exon 1116..1262
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 1117
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:141851225"
variation 1127
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201781724"
variation 1142
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:146104501"
variation 1147
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:202044032"
variation 1159
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139055681"
variation 1172
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:374744056"
variation 1178
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:114856527"
variation 1192
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:149128755"
variation 1217
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:116346810"
variation 1226
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:56041613"
exon 1263..1436
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 1288
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:148312044"
variation 1301
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:202161442"
variation 1302
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:141758720"
variation 1347
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200238437"
variation 1388
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:432998"
variation 1397
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="g"
/replace="t"
/db_xref="dbSNP:141827066"
variation 1434
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="t"
/db_xref="dbSNP:369508594"
variation 1435
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="g"
/replace="t"
/db_xref="dbSNP:201855972"
exon 1437..1528
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 1463
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:55942437"
variation 1502
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:369762663"
exon 1529..1591
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 1568
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376961976"
variation 1579
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370646498"
variation 1589
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200457901"
exon 1592..1730
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 1696
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/db_xref="dbSNP:111341519"
variation 1721
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:17847876"
variation 1727
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:367690547"
exon 1731..1811
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 1745
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:376039132"
exon 1812..1919
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 1869
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:368238909"
variation 1884
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:17847879"
exon 1920..2060
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 1920
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/db_xref="dbSNP:201555288"
variation 1960
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:35631544"
variation 1967
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:3729904"
variation 1989
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:114846751"
variation 2047
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="t"
/db_xref="dbSNP:371799088"
exon 2061..8014
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/inference="alignment:Splign:1.39.8"
variation 2068
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374654582"
variation 2084
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:369345275"
variation 2108
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="t"
/db_xref="dbSNP:149446950"
variation 2165
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:143953612"
variation 2228
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199871261"
variation 2238
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369724465"
variation 2266
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373045947"
STS 2335..2690
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/standard_name="GDB:180922"
/db_xref="UniSTS:155127"
variation 2347
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="t"
/db_xref="dbSNP:3380"
variation 2366
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:146020925"
variation 2397
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:41280844"
variation 2433
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:4787872"
variation 2474
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:149339486"
variation 2476
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:189252078"
STS 2594..2920
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/standard_name="D16S3216"
/db_xref="UniSTS:56316"
variation 2603
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:144672987"
variation 2605
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:148546127"
variation 2610
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:114644570"
variation 2688
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:78674142"
variation 2697
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/db_xref="dbSNP:370678030"
STS 2791..2891
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/standard_name="A009H10"
/db_xref="UniSTS:70339"
STS 2791..2891
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/standard_name="G32537"
/db_xref="UniSTS:117121"
variation 2795
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:142859099"
variation 2822
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:3785380"
variation 3000
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:182199378"
variation 3016
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:3785379"
variation 3027
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:147723634"
variation 3043..3052
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="tctttttttt"
/db_xref="dbSNP:3837785"
variation 3052..3061
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="aaaaaaaaag"
/db_xref="dbSNP:72271620"
variation 3052
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:79376982"
variation 3107
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:3785378"
variation 3113
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374468788"
variation 3139
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:56687328"
variation 3167
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:185582992"
variation 3230
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="g"
/replace="t"
/db_xref="dbSNP:116093872"
variation 3237
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:371790470"
variation 3379
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:140893375"
variation 3385
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/db_xref="dbSNP:71379853"
variation 3389
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="t"
/db_xref="dbSNP:371807314"
variation 3390
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="a"
/db_xref="dbSNP:59543980"
variation 3391
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="t"
/db_xref="dbSNP:79997806"
variation 3401
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:116357421"
variation 3403
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:76359194"
variation 3444
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="g"
/replace="t"
/db_xref="dbSNP:78750834"
variation 3515
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:8059889"
variation 3518
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:113196567"
variation 3558
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:190191882"
variation 3621
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374319540"
variation 3735
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:147946613"
variation 3757
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:181718271"
variation 3780
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="c"
/db_xref="dbSNP:35860232"
variation 3784
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:185391750"
variation 3810
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:41303765"
variation 3843
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:368007255"
variation 3844
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:75859222"
variation 3850
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:112729951"
variation 3858
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:140599804"
variation 3971
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:113823327"
variation 3983
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:190250028"
variation 4021
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:114738789"
variation 4046
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/db_xref="dbSNP:181254533"
variation 4055
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="c"
/db_xref="dbSNP:138855260"
variation 4056
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:185977261"
variation 4150
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="t"
/db_xref="dbSNP:371761150"
variation 4178
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="t"
/db_xref="dbSNP:114136375"
STS 4273..4396
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/standard_name="RH68302"
/db_xref="UniSTS:74925"
variation 4290
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:114638203"
STS 4302..4442
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/standard_name="RH93580"
/db_xref="UniSTS:89925"
variation 4319
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150101137"
STS 4355..4457
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/standard_name="SHGC-30376"
/db_xref="UniSTS:75040"
variation 4399
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/db_xref="dbSNP:73550432"
variation 4405
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:145450586"
variation 4475
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:41309270"
variation 4497
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="t"
/db_xref="dbSNP:41311262"
variation 4504
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:3209801"
variation 4508
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:1131276"
variation 4511
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:1131277"
variation 4512
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="t"
/db_xref="dbSNP:190798839"
variation 4561
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="a"
/db_xref="dbSNP:145016072"
variation 4585
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:2021847"
variation 4661
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:148858748"
STS 4681..4860
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/standard_name="SHGC-61073"
/db_xref="UniSTS:5058"
variation 4691
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="t"
/db_xref="dbSNP:371842506"
variation 4705
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:145309658"
variation 4752
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="g"
/replace="t"
/db_xref="dbSNP:41313541"
variation 4809
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369926841"
variation 4858..4859
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="c"
/db_xref="dbSNP:34197974"
variation 5055
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/db_xref="dbSNP:34097947"
variation 5185
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:138047682"
variation 5268
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:140957380"
variation 5275
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="g"
/replace="t"
/db_xref="dbSNP:41311260"
variation 5283
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/db_xref="dbSNP:41311258"
variation 5377
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:183896121"
variation 5424
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:144891284"
variation 5493
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="t"
/db_xref="dbSNP:188939352"
variation 5715
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:77825011"
variation 5734
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138780084"
variation 5740
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:28552982"
variation 5781
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:41303763"
variation 5797
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:150831990"
variation 5891
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:2239338"
variation 5924
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/db_xref="dbSNP:73550434"
variation 5946..5947
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="g"
/db_xref="dbSNP:34630014"
variation 5967
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:2239339"
variation 6022
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="g"
/replace="t"
/db_xref="dbSNP:138123553"
variation 6052..6053
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="ga"
/db_xref="dbSNP:34045233"
variation 6053..6054
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="ga"
/db_xref="dbSNP:371140609"
variation 6059..6060
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="ga"
/db_xref="dbSNP:68056200"
variation 6082
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:147259878"
variation 6085
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:140931038"
variation 6099
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:191748340"
variation 6139
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:35434839"
variation 6190
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369641483"
variation 6226
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:41311256"
variation 6257
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:374358833"
variation 6264
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:376874115"
variation 6285
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="t"
/db_xref="dbSNP:411103"
variation 6319
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:11865035"
variation 6332
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:8056058"
variation 6347
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:3087957"
variation 6400
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:148593800"
STS 6429..6595
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/standard_name="D16S2580E"
/db_xref="UniSTS:151657"
STS 6436..6588
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/standard_name="D16S2567E"
/db_xref="UniSTS:44884"
variation 6496
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:113354788"
variation 6517
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:183148409"
variation 6591..6592
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="a"
/db_xref="dbSNP:139806286"
variation 6648..6649
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="ttttg"
/replace="ttttgttttgttttg"
/replace="ttttgttttgttttgttttg"
/db_xref="dbSNP:10639027"
variation 6648
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:199618218"
variation 6649..6650
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="ttttg"
/db_xref="dbSNP:35423969"
variation 6665..6666
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="ttgttttgtt"
/db_xref="dbSNP:10681565"
variation 6666..6667
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="tgttt"
/replace="ttgttttgtt"
/db_xref="dbSNP:10681566"
variation 6667..6668
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="tgttt"
/db_xref="dbSNP:35889059"
variation 6668..6669
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="gttttgtttt"
/db_xref="dbSNP:71907097"
variation 6677..6678
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="gtttt"
/replace="gttttgttttgtttt"
/db_xref="dbSNP:10657133"
variation 6678..6679
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="gtttt"
/db_xref="dbSNP:72080067"
variation 6733..6734
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="tagat"
/db_xref="dbSNP:138369749"
variation 6734..6735
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="gatta"
/db_xref="dbSNP:201843272"
variation 6734
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="t"
/db_xref="dbSNP:111528401"
variation 6737..6738
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="tagat"
/db_xref="dbSNP:3216342"
variation 6737
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:77746351"
variation 6738..6739
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="tagat"
/db_xref="dbSNP:35283079"
variation 6762
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:2239340"
variation 6773
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="g"
/replace="t"
/db_xref="dbSNP:187559261"
variation 6896
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:191675978"
variation 6915
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:184182024"
variation 6970
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:78946887"
variation 6985
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:397299"
variation 7058..7059
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:395078"
variation 7058..7059
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="cc"
/replace="ccac"
/db_xref="dbSNP:374966048"
variation 7058
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="a"
/db_xref="dbSNP:200055220"
variation 7059..7075
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="acacacacacacacaca"
/db_xref="dbSNP:368430381"
variation 7059..7060
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="cc"
/replace="ccac"
/db_xref="dbSNP:67800762"
variation 7059
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="a"
/replace="aca"
/db_xref="dbSNP:371994904"
variation 7059
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/db_xref="dbSNP:28605861"
variation 7063
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="a"
/db_xref="dbSNP:34377767"
variation 7066..7067
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="acac"
/db_xref="dbSNP:10655858"
variation 7067..7068
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="caca"
/db_xref="dbSNP:10645988"
variation 7068..7069
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="ac"
/db_xref="dbSNP:10657134"
variation 7069..7070
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="acac"
/db_xref="dbSNP:71753246"
variation 7077..7078
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="gcac"
/db_xref="dbSNP:377077346"
variation 7096..7097
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="ca"
/db_xref="dbSNP:5816244"
variation 7102..7105
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="ca"
/db_xref="dbSNP:34565623"
variation 7114..7115
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="gg"
/db_xref="dbSNP:201572518"
variation 7317
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377532181"
variation 7330
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:3729908"
variation 7334
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:41278144"
variation 7344
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200017388"
variation 7360
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:202022036"
variation 7426
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:148637931"
variation 7494
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:142427207"
variation 7531
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:424741"
variation 7532
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:367894275"
variation 7534
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:140062455"
variation 7535
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374831115"
STS 7560..7809
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/standard_name="RH70812"
/db_xref="UniSTS:13194"
variation 7607
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:187700395"
variation 7630
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:113336763"
variation 7669
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:192474372"
variation 7700
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="g"
/db_xref="dbSNP:185685652"
variation 7712
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368074978"
variation 7713
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="a"
/replace="g"
/db_xref="dbSNP:190510502"
variation 7789
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:181492069"
STS 7883..7983
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/standard_name="WI-12240"
/db_xref="UniSTS:20984"
variation 7904
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:144042856"
variation 7933..7934
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace=""
/replace="t"
/db_xref="dbSNP:34526646"
variation 7942
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:1063471"
variation 7955
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
/replace="c"
/replace="t"
/db_xref="dbSNP:146441057"
polyA_signal 7991..7996
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
polyA_site 8014
/gene="PRKCB"
/gene_synonym="PKC-beta; PKCB; PRKCB1; PRKCB2"
ORIGIN
agctggacgagcggcagcagctgggcgagtgacagccccggctccgcgcgccgcggccgccagagccggcgcaggggaagcgcccgcggccccgggtgcagcagcggccgccgcctcccgcgcctccccggcccgcagcccgcggtcccgcggccccggggccggcacctctcgggctccggctccccgcgcgcaagatggctgacccggctgcggggccgccgccgagcgagggcgaggagagcaccgtgcgcttcgcccgcaaaggcgccctccggcagaagaacgtgcatgaggtcaagaaccacaaattcaccgcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttcgggaagcagggattccagtgccaagtttgctgctttgtggtgcacaagcggtgccatgaatttgtcacattctcctgccctggcgctgacaagggtccagcctccgatgacccccgcagcaaacacaagtttaagatccacacgtactccagccccacgttttgtgaccactgtgggtcactgctgtatggactcatccaccaggggatgaaatgtgacacctgcatgatgaatgtgcacaagcgctgcgtgatgaatgttcccagcctgtgtggcacggaccacacggagcgccgcggccgcatctacatccaggcccacatcgacagggacgtcctcattgtcctcgtaagagatgctaaaaaccttgtacctatggaccccaatggcctgtcagatccctacgtaaaactgaaactgattcccgatcccaaaagtgagagcaaacagaagaccaaaaccatcaaatgctccctcaaccctgagtggaatgagacatttagatttcagctgaaagaatcggacaaagacagaagactgtcagtagagatttgggattgggatttgaccagcaggaatgacttcatgggatctttgtcctttgggatttctgaacttcagaaagccagtgttgatggctggtttaagttactgagccaggaggaaggcgagtacttcaatgtgcctgtgccaccagaaggaagtgaggccaatgaagaactgcggcagaaatttgagagggccaagatcagtcagggaaccaaggtcccggaagaaaagacgaccaacactgtctccaaatttgacaacaatggcaacagagaccggatgaaactgaccgattttaacttcctaatggtgctggggaaaggcagctttggcaaggtcatgctttcagaacgaaaaggcacagatgagctctatgctgtgaagatcctgaagaaggacgttgtgatccaagatgatgacgtggagtgcactatggtggagaagcgggtgttggccctgcctgggaagccgcccttcctgacccagctccactcctgcttccagaccatggaccgcctgtactttgtgatggagtacgtgaatgggggcgacctcatgtatcacatccagcaagtcggccggttcaaggagccccatgctgtattttacgctgcagaaattgccatcggtctgttcttcttacagagtaagggcatcatttaccgtgacctaaaacttgacaacgtgatgctcgattctgagggacacatcaagattgccgattttggcatgtgtaaggaaaacatctgggatggggtgacaaccaagacattctgtggcactccagactacatcgcccccgagataattgcttatcagccctatgggaagtccgtggattggtgggcatttggagtcctgctgtatgaaatgttggctgggcaggcaccctttgaaggggaggatgaagatgaactcttccaatccatcatggaacacaacgtagcctatcccaagtctatgtccaaggaagctgtggccatctgcaaagggctgatgaccaaacacccaggcaaacgtctgggttgtggacctgaaggcgaacgtgatatcaaagagcatgcatttttccggtatattgattgggagaaacttgaacgcaaagagatccagcccccttataagccaaaagcttgtgggcgaaatgctgaaaacttcgaccgatttttcacccgccatccaccagtcctaacacctcccgaccaggaagtcatcaggaatattgaccaatcagaattcgaaggattttcctttgttaactctgaatttttaaaacccgaagtcaagagctaagtagatgtgtagatctccgtccttcatttctgtcattcaagctcaacggctattgtggtgacatttttatgtttttcattgccaagttgcatccatgtttgattttctgatgagactagagtgacagtgtttcagaacccaaatgtcctcaggtagtttggagcatctctatgagatgggattatgcagatggcctatggaaaatgcagctgcataattaacacattatcaaagtcctcttacaatttattttccgcagcatgtcagctaagtagacccaatggggagagaaaatgcctgctttctttccctctttttctgcactgccatattcacccccaaccatccaatctgtggataattggatgttagcggtactcttccacttccgggcctggagcttggcttgtatccaagtgtatggttgctttgcctaagaggaatccctctatttcacctgttctggaggcaccagaccttgaaaagaacatgctcaaaataaaatgttatctgttatttttgtaaactcaaagttaagatgatcaaagttctaaaattccaagaatgtgcttttagacggtctcaatctaaaagcacttcaaggggtcaaagggcaaccagcttgggtgctacctcagtgttgtagtttctgatactttatgtctttgctcaccctcatccccaaactacttgaaaagggcatttggcaccactctctgaaacaacacagtcactctagcaaggcccccaaagggccctggttttacattacatttcaaactttatttgctttggggttttgtttctgttgttgttcaaatgcaaaaaaaagaaaaaaaaagaaaaaaaaaggtgactcacattgttacacatgctttaaaatatgtattcaaatgttattaaccacaatgacgacctgctttgatttaaccaagaagacggctgcggagcctagcagactcaggcctgtgggaatgggatttgttacaaatctaggtttgttactggcttcagaaagctaattaagtgctctgaaaaagacaccgtttcttgaaacaaagatggttgtattcctcactttgatgttgttttgcaagatgtttgtggaaatgttcatttgtatctggatctctgttatgtgccatttttcttctagcatcgagatacaataaaaaaaaaaaaaaagaaaagaagaagaaatactatttcaaggaaaactgctctttttgagaaacgtggacctaaactacaaagtgggaactgaggagggaactcaggagaaaggaactaactgcggagctttaatcttggccccagtgttcagccactcggaggggcgggggctgtggcccattcaggggctgctggtgggctgtagtggggtgggatgacctggccagagccaacgaggatactggagcccaaagtcaagtttagagaccagctgggaacgtgaatggggctcttgattttcttatcaaaatcaccactcctcccagcttggactaaatattctttctagcaagcagctttgtgagctccctgaagcccaaggaaacccttcggtgggagaaatttcatttctgtctgagaggattaaggcagcaggtgactccccctcctcgcctgccgtgtcctgctattctcaggcagctctaaggagaattcttatcacagttcaagtgatttccagaagttccagggcttctgagagaccatcaagggaactttaacaacttgacaaatgtccttgaagtaagatgcctcatctttagggaaaaatggggtttggatttctgcttaggcaaagtctcctgcagttcatccttctctgtcctcttcttgcttcaggcttggggaccgtccctgctgtccccactgtggtggcaatcaggacctaaggtgaagcaaacttgaagttctatctgacaagtttaggcagtaagagaaggagggaaatcggagcaaagctccctcactttattgttgagaaactggcatctggaaagaggaaggaatttgcccaaagtcagtcagctgggataaaaacctgggtgtcctgtccagaaagtgcagggtgctttctgctctgtagcaaggcagcagacatctctgagccaggcccaccaacaggcccttatctggtggttggatcatgatcccattttgcttggacatgctctcaggaagataaaaaccatggagaaacactaggccattgacaaatgatctgagacaactttagaaaacaatgtaggatgaatggaaagagaaagaaaggaaagaaagaagaaaaagaaagaaggaaagaaagaaagagaaaggaaggaaggaaagaaggaaggaaaagaaggaaggaaggaaggaatatagtgttataaatactgcactcaacattttccaaattcttgccattatttttcaaaagtttaatagtttgcagaaatagatactcaagccaaagtctgttttagagaaactttccatggaaagtcagaatttctaccacttccttttctatccacatttccagtgcagaagaaactgagaaacagagctttttgaagagaggacagggccatagcaacaaggaccttcttgggggattaatgggaggtcagtagaattaataaccctccttggatgagtgctactgttttcacatggcttcagatgctatcaacctcaaagaaatgatctcaacagagaagcttattctctcccaacttctacggtaaaatccaggagtattttctctggggatctgcccacaggacaaagtccataaaagcaagtcctgtctggaccatgtggttatctgaagcattagccatcaccagcacaacaaacggggcagggctttccaaggtggggctggtcagaagggaatctttgataagaggcccacaggcagggaaagcgaaatagggttgatgagaccaggggagacctaaaaaaaaggcagctttgtgtcttctagctccaaatatacctgccttttagctcacacactgtcctggagttctcagacctttaggggccctaacacagttcagttcatacaggggttcaaaagggacagtggcccatttgggagacctttaggatcaatgggaatcaattccattgttttgcctcagagtaaagtttctggctcggggacaattataagttgcaaaaaggatagaggcatatcccaagtcttccttcattccacaaataattacaaacaacctactgtgtgccaggcactattcttagcactggaaatacactagtgaagaagcagatgaggaccctgtttattgtttctctccaagaaattctccaagaatattgtttcttggagagaaataataaataaacaagacaatttctgaaagcaataagtgcaatcaagataattaaaggatgctaaagtgtgacttgtggggattgggagagagatgcacagacaatattaaagaggaggcattcgagctttgttgtgaacaccggaagtaacatgccgagcgcctgggggatggaaactcctatagcaccccacaggctaacagcaagcaggacaagacaaaaagggcaggtgggacatggtagagatggaccctacccaggaaacagctccatcagcatcttagcctgccccactctagccacacatacccacgtgtgctcctgagttcagtgtgcccacctcactcccacaccctcacatagacttggcaagagtaaggagggaactccatagagacattttacctatctcaggggagcagccacaaagaagcaagtcttgtaaaaggtcttttgcaaaggagagtgaacccagcaatgagagatccttaacagctagtgcccattagggggctaaacctaaagcctgggtggtgatggctcaaacgctaatgagtcagtgaatccttaccgaccccctggcctttataatctgaggcaactttggctgcagcccgggaatgtgcagggcactagggaatacaaggccttcttccctggttgtcttgtaataaaacagccatggggttgtccctccagtccgagagactgtgatgaggcctacatagcagcgatgtggtcaggtaaaaatcaggaacccactgaaatcttgggcaagccaccctgcctgcttgtgcctcggttctctcatatgtcatatataggaggtgaggactccagctccacctgccccaggtgggtgtggtgatgatgaggaaagacaagaggcttgcaaggaccctgaagaggtcggagcatcatacagattcctttattagcccacattctgatgttccctggtgagacttgccccaagcaattgctagtaaatgggggttaatttcttctccacctccctactgaacaaaaaaagaaatgccagacttactaggagaatcgagttgctttgagtttcttttgttttgttttgttttgttttgttttaaggctccccttacacaccctcctttaagctttgggttttctctcttatagtttgttgacacatgctaaaaatgtctttggagagaacttctgcctgataaacacccaattctagactgtgggtggattttcgagctgacggtggtcaattcctttcattaagcagtgatctgatttctccacatggccattctgccttcttgggggcagagtagatgggcagcagttcaccttttcagagaaagaggtcttctagccacctgggctgctactgaatggttttctccaggacgctctacctaatgattatttctataacattaagcatggtaataagtagcttccaattcaattcatcctaaagccaaagaaaatacagcaacacacacacacacacacacacacacacacacacacacacacacacaccactttatggcaattcttaactgacattcaatgacttacttcttttcttagaaaatttccaccacatttctatccccaagccaacatacaatgtgaaatgaaagccagtgcgtggagtgcagctgctaaaaattttcagcacagggctctttctgactctgctcatgagatggtatcagccacccaatgactggcgtatcttggtcctgtgtctttcttcttacgctgtgttaatgtgtttactttccatttggcagagagacaagagagacacctccaacttcgacaaagagttcaccagacagcctgtggaactgacccccactgataaactcttcatcatgaacttggaccaaaatgaatttgctggcttctcttatactaacccagagtttgtcattaatgtgtaggtgaatgcaaactccatcgttgagcctggggtgtaagacttcaagccaagcgtatgtatcaattctagtcttccaggattcacggtgcacatgctggcattcaacatgtggaaagcttgtcttagagggcttttctttgtatgtgtagcttgctagtttgttttctacatttgaaaatgtttagtttagaataagcgcattatccaattatagaggtacaattttccaaacttccagaaactcatcaaatgaacagacaatgtcaaaactactgtgtctgataccaaaatgcttcagtatttgtaatttttcaagtcagaagctgatgttcctggtaaaagtttttacagttattctataatatcttctttgaatgctaagcatgagcgatatttttaaaaattgtgagtaagctttgcagttactgtgaactattgtctcttggaggaagttttttgtttaagaattgatatgattaaactgaattaatatatgcaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:5579 -> Molecular function: GO:0003682 [chromatin binding] evidence: IDA
GeneID:5579 -> Molecular function: GO:0004674 [protein serine/threonine kinase activity] evidence: TAS
GeneID:5579 -> Molecular function: GO:0004697 [protein kinase C activity] evidence: IEA
GeneID:5579 -> Molecular function: GO:0005080 [protein kinase C binding] evidence: IPI
GeneID:5579 -> Molecular function: GO:0005246 [calcium channel regulator activity] evidence: IEA
GeneID:5579 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:5579 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
GeneID:5579 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA
GeneID:5579 -> Molecular function: GO:0030374 [ligand-dependent nuclear receptor transcription coactivator activity] evidence: IMP
GeneID:5579 -> Molecular function: GO:0035403 [histone kinase activity (H3-T6 specific)] evidence: IDA
GeneID:5579 -> Molecular function: GO:0042393 [histone binding] evidence: IDA
GeneID:5579 -> Molecular function: GO:0050681 [androgen receptor binding] evidence: IDA
GeneID:5579 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
GeneID:5579 -> Biological process: GO:0006357 [regulation of transcription from RNA polymerase II promoter] evidence: IMP
GeneID:5579 -> Biological process: GO:0006468 [protein phosphorylation] evidence: TAS
GeneID:5579 -> Biological process: GO:0006816 [calcium ion transport] evidence: IEA
GeneID:5579 -> Biological process: GO:0006874 [cellular calcium ion homeostasis] evidence: IEA
GeneID:5579 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:5579 -> Biological process: GO:0007165 [signal transduction] evidence: NAS
GeneID:5579 -> Biological process: GO:0007268 [synaptic transmission] evidence: TAS
GeneID:5579 -> Biological process: GO:0007596 [blood coagulation] evidence: TAS
GeneID:5579 -> Biological process: GO:0010829 [negative regulation of glucose transport] evidence: ISS
GeneID:5579 -> Biological process: GO:0030168 [platelet activation] evidence: TAS
GeneID:5579 -> Biological process: GO:0030949 [positive regulation of vascular endothelial growth factor receptor signaling pathway] evidence: ISS
GeneID:5579 -> Biological process: GO:0035408 [histone H3-T6 phosphorylation] evidence: IDA
GeneID:5579 -> Biological process: GO:0035556 [intracellular signal transduction] evidence: IEA
GeneID:5579 -> Biological process: GO:0042113 [B cell activation] evidence: ISS
GeneID:5579 -> Biological process: GO:0042953 [lipoprotein transport] evidence: TAS
GeneID:5579 -> Biological process: GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB cascade] evidence: ISS
GeneID:5579 -> Biological process: GO:0045766 [positive regulation of angiogenesis] evidence: ISS
GeneID:5579 -> Biological process: GO:0046627 [negative regulation of insulin receptor signaling pathway] evidence: ISS
GeneID:5579 -> Biological process: GO:0050853 [B cell receptor signaling pathway] evidence: ISS
GeneID:5579 -> Biological process: GO:0050861 [positive regulation of B cell receptor signaling pathway] evidence: ISS
GeneID:5579 -> Biological process: GO:0051092 [positive regulation of NF-kappaB transcription factor activity] evidence: ISS
GeneID:5579 -> Biological process: GO:0071322 [cellular response to carbohydrate stimulus] evidence: IEA
GeneID:5579 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:5579 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:5579 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:5579 -> Cellular component: GO:0005886 [plasma membrane] evidence: IDA
GeneID:5579 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_002729 -> EC 2.7.11.13
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.