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2024-04-20 02:56:57, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_002698 6904 bp mRNA linear PRI 17-APR-2013 DEFINITION Homo sapiens POU class 2 homeobox 2 (POU2F2), transcript variant 2, mRNA. ACCESSION NM_002698 VERSION NM_002698.4 GI:351542188 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 6904) AUTHORS Saglam,A. and Uner,A.H. TITLE Immunohistochemical expression of Mum-1, Oct-2 and Bcl-6 in systemic anaplastic large cell lymphomas JOURNAL Tumori 97 (5), 634-638 (2011) PUBMED 22158496 REMARK GeneRIF: Half of the cases displayed Oct-2 expression (15/30 cases) of systemic anaplastic large-cell lymphoma measured by tissue microarray immunohistochemistry. REFERENCE 2 (bases 1 to 6904) AUTHORS Herbeck,R., Teodorescu Brinzeu,D., Giubelan,M., Lazar,E., Dema,A. and Ionita,H. TITLE B-cell transcription factors Pax-5, Oct-2, BOB.1, Bcl-6, and MUM1 are useful markers for the diagnosis of nodular lymphocyte predominant Hodgkin lymphoma JOURNAL Rom J Morphol Embryol 52 (1), 69-74 (2011) PUBMED 21424034 REMARK GeneRIF: Twenty-two cases of nodular lymphocyte predominant Hodgkin lymphoma were studied for the immunohistochemical expression of Pax-5, Oct-2, BOB.1, Bcl-6 protein and MUM1/IRF-4. REFERENCE 3 (bases 1 to 6904) AUTHORS Bailey,S.D., Xie,C., Do,R., Montpetit,A., Diaz,R., Mohan,V., Keavney,B., Yusuf,S., Gerstein,H.C., Engert,J.C. and Anand,S. CONSRTM DREAM investigators TITLE Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study JOURNAL Diabetes Care 33 (10), 2250-2253 (2010) PUBMED 20628086 REMARK GeneRIF: Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) REFERENCE 4 (bases 1 to 6904) AUTHORS Galetti,M., Alfieri,R.R., Cavazzoni,A., La Monica,S., Bonelli,M., Fumarola,C., Mozzoni,P., De Palma,G., Andreoli,R., Mutti,A., Mor,M., Tiseo,M., Ardizzoni,A. and Petronini,P.G. TITLE Functional characterization of gefitinib uptake in non-small cell lung cancer cell lines JOURNAL Biochem. Pharmacol. 80 (2), 179-187 (2010) PUBMED 20363215 REMARK GeneRIF: Gefitinib may exert an inhibitory effect on the intracellular accumulation of drugs transported by hOCT1 and hOCT2. REFERENCE 5 (bases 1 to 6904) AUTHORS Advani,A.S., Lim,K., Gibson,S., Shadman,M., Jin,T., Copelan,E., Kalaycio,M., Sekeres,M.A., Sobecks,R. and Hsi,E. TITLE OCT-2 expression and OCT-2/BOB.1 co-expression predict prognosis in patients with newly diagnosed acute myeloid leukemia JOURNAL Leuk. Lymphoma 51 (4), 606-612 (2010) PUBMED 20141429 REMARK GeneRIF: OCT-2 may act as a cell survival factor in acute myeloid leukemia by mediating expression of downstream targets, such as BCL-2. REFERENCE 6 (bases 1 to 6904) AUTHORS Muller-Immergluck,M.M., Schaffner,W. and Matthias,P. TITLE Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells JOURNAL EMBO J. 9 (5), 1625-1634 (1990) PUBMED 2328728 REFERENCE 7 (bases 1 to 6904) AUTHORS Scheidereit,C., Cromlish,J.A., Gerster,T., Kawakami,K., Balmaceda,C.G., Currie,R.A. and Roeder,R.G. TITLE A human lymphoid-specific transcription factor that activates immunoglobulin genes is a homoeobox protein JOURNAL Nature 336 (6199), 551-557 (1988) PUBMED 2904654 REFERENCE 8 (bases 1 to 6904) AUTHORS Muller,M.M., Ruppert,S., Schaffner,W. and Matthias,P. TITLE A cloned octamer transcription factor stimulates transcription from lymphoid-specific promoters in non-B cells JOURNAL Nature 336 (6199), 544-551 (1988) PUBMED 2904653 REFERENCE 9 (bases 1 to 6904) AUTHORS Clerc,R.G., Corcoran,L.M., LeBowitz,J.H., Baltimore,D. and Sharp,P.A. TITLE The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains JOURNAL Genes Dev. 2 (12A), 1570-1581 (1988) PUBMED 3265124 REFERENCE 10 (bases 1 to 6904) AUTHORS Ko,H.S., Fast,P., McBride,W. and Staudt,L.M. TITLE A human protein specific for the immunoglobulin octamer DNA motif contains a functional homeobox domain JOURNAL Cell 55 (1), 135-144 (1988) PUBMED 2901913 COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M36653.1, BC006101.1, M36718.1, AC022515.5 and BF062323.1. On Oct 14, 2011 this sequence version replaced gi:333360871. Summary: The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]. Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: M36542.1, X13810.1 [ECO:0000331] RNAseq introns :: single sample supports all introns ERS025089, ERS025095 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-8 M36653.1 5-12 9-1212 BC006101.1 1-1204 1213-1911 M36718.1 1196-1894 1912-6843 AC022515.5 2762-7693 6844-6904 BF062323.1 1-61 c FEATURES Location/Qualifiers source 1..6904 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="19" /map="19q13.2" gene 1..6904 /gene="POU2F2" /gene_synonym="Oct-2; OCT2; OTF2" /note="POU class 2 homeobox 2" /db_xref="GeneID:5452" /db_xref="HGNC:9213" /db_xref="HPRD:01251" /db_xref="MIM:164176" exon 1..90 /gene="POU2F2" /gene_synonym="Oct-2; OCT2; OTF2" /inference="alignment:Splign:1.39.8" misc_feature 24..26 /gene="POU2F2" /gene_synonym="Oct-2; OCT2; OTF2" /note="upstream in-frame stop codon" CDS 63..1454 /gene="POU2F2" /gene_synonym="Oct-2; OCT2; OTF2" /note="isoform 2 is encoded by transcript variant 2; POU domain, class 2, transcription factor 2; homeobox protein; OTF-2; octamer-binding protein 2; octamer-binding transcription factor 2; lymphoid-restricted immunoglobulin octamer-binding protein NF-A2" /codon_start=1 /product="POU domain, class 2, transcription factor 2 isoform 2" /protein_id="NP_002689.1" /db_xref="GI:4505959" /db_xref="CCDS:CCDS33035.1" /db_xref="GeneID:5452" /db_xref="HGNC:9213" /db_xref="HPRD:01251" /db_xref="MIM:164176" /translation="
MVHSSMGAPEIRMSKPLEAEKQGLDSPSEHTDTERNGPDTNHQNPQNKTSPFSVSPTGPSTKIKAEDPSGDSAPAAPLPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAGLPTQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPASYSPHMVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGPGLWWNPAPYQP
"
misc_feature 597..821
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/note="Found in Pit-Oct-Unc transcription factors; Region:
POU; smart00352"
/db_xref="CDD:197673"
misc_feature 906..1076
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/note="Homeodomain; DNA binding domains involved in the
transcriptional regulation of key eukaryotic developmental
processes; may bind to DNA as monomers or as homo- and/or
heterodimers, in a sequence-specific manner; Region:
homeodomain; cd00086"
/db_xref="CDD:28970"
misc_feature order(906..920,924..926,975..977,993..995,1032..1034,
1038..1043,1050..1055,1059..1067,1071..1076)
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:28970"
misc_feature order(912..914,921..923,1041..1043,1050..1055,1062..1064)
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/note="specific DNA base contacts [nucleotide binding];
other site"
/db_xref="CDD:28970"
exon 91..156
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/inference="alignment:Splign:1.39.8"
exon 157..191
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/inference="alignment:Splign:1.39.8"
exon 192..248
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/inference="alignment:Splign:1.39.8"
exon 249..365
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/inference="alignment:Splign:1.39.8"
exon 366..471
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/inference="alignment:Splign:1.39.8"
exon 472..563
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/inference="alignment:Splign:1.39.8"
exon 564..677
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/inference="alignment:Splign:1.39.8"
STS 569..808
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/standard_name="POU2F2"
/db_xref="UniSTS:253999"
exon 678..819
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/inference="alignment:Splign:1.39.8"
exon 820..968
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/inference="alignment:Splign:1.39.8"
exon 969..1145
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/inference="alignment:Splign:1.39.8"
exon 1146..1212
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/inference="alignment:Splign:1.39.8"
exon 1213..1414
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/inference="alignment:Splign:1.39.8"
exon 1415..6896
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/inference="alignment:Splign:1.39.8"
STS 1525..2230
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/standard_name="POU2F2__1992"
/db_xref="UniSTS:280918"
STS 1643..1748
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/standard_name="G10665"
/db_xref="UniSTS:32972"
STS 1659..2657
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/standard_name="ha2919"
/db_xref="UniSTS:515610"
STS 2564..2772
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/standard_name="A009Q47"
/db_xref="UniSTS:19691"
STS 2564..2772
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/standard_name="G32794"
/db_xref="UniSTS:117373"
variation 3245
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/replace="a"
/replace="t"
/db_xref="dbSNP:1062539"
variation 3272
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/replace="a"
/replace="c"
/db_xref="dbSNP:1714253"
polyA_site 3650
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
STS 4345..4473
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/standard_name="WI-11723"
/db_xref="UniSTS:27568"
variation 5674
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/replace="c"
/replace="t"
/db_xref="dbSNP:1056995"
STS 6647..6769
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/standard_name="A007A14"
/db_xref="UniSTS:58884"
STS 6741..6866
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
/standard_name="WI-12372"
/db_xref="UniSTS:63841"
polyA_signal 6863..6868
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
polyA_signal 6871..6876
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
polyA_site 6896
/gene="POU2F2"
/gene_synonym="Oct-2; OCT2; OTF2"
ORIGIN
ggcccccagagagggtggggagatgacacagttgttcccccagccctggcggggcgggcagcatggttcactccagcatgggggctccagaaataagaatgtctaagcccctggaggccgagaagcaaggtctggactccccatcagagcacacagacaccgaaagaaatggaccagacactaatcatcagaacccccaaaataagacctccccattctccgtgtccccaactggccccagtacaaagatcaaggctgaagaccccagtggcgattcagccccagcagcacccctgccccctcagccggcccagcctcatctgccccaggcccaactcatgttgacgggcagccagctagctggggacatacagcagctcctccagctccagcagctggtgcttgtgccaggccaccacctccagccacctgctcagttcctgctaccgcaggcccagcagagccagccaggcctgctaccgacaccaaatctattccagctacctcagcaaacccagggagctcttctgacctcccagccccgggccgggcttcccacacagccccccaaatgcttggagccaccatcccaccccgaggagcccagtgatctggaggagctggagcaattcgcccgcaccttcaagcaacgccgcatcaagctgggcttcacgcagggtgatgtgggcctggccatgggcaagctctacggcaacgacttcagccagacgaccatttcccgcttcgaggccctcaacctgagcttcaagaacatgtgcaaactcaagcccctcctggagaagtggctcaacgatgcagagactatgtctgtggactcaagcctgcccagccccaaccagctgagcagccccagcctgggtttcgacggcctgcccggccggagacgcaagaagaggaccagcatcgagacaaacgtccgcttcgccttagagaagagttttctagcgaaccagaagcctacctcagaggagatcctgctgatcgccgagcagctgcacatggagaaggaagtgatccgcgtctggttctgcaaccggcgccagaaggagaaacgcatcaacccctgcagtgcggcccccatgctgcccagcccagggaagccggccagctacagcccccatatggtcacaccccaagggggcgcggggaccttaccgttgtcccaagcttccagcagtctgagcacaacagttactaccttatcctcagctgtggggacgctccaccccagccggacagctggagggggtgggggcgggggcggggctgcgccccccctcaattccatcccctctgtcactcccccacccccggccaccaccaacagcacaaaccccagccctcaaggcagccactcggctatcggcttgtcaggcctgaaccccagcacgggccctggcctctggtggaaccctgccccttaccagccttgatggcagcgggaatctggtgctgggggcagccggtgcagccccggggagccctggcctggtgacctcgccgctcttcttgaatcatgctgggctgcccctgctcagcaccccgcctggtgtgggcctggtctcagcagcggctgcggctgtggcagcctccatctccagcaagtctcctggcctctcctcctcatcctcttcatcctcatcctcctcctcctccacttgcagcgagacggcagcacagacccctggaggtccaggggggcccgaggcagggtccaaacctgagtgagggccagccatgcctcccctcccattcctctggtccctgccttggtcccttgcctgggaagagggcgaggaggccagtggtggggacgcagagggtcctcagagcaggagtgacaagggaggaaagaccaaaaaaacaaccaaccaaaaaaaaaaaaaaaaaggaaagaaactaaccaacaaaagagaaaaccaaaaataatcacaacagaaaccagctgccccaaaggaaccagaggtgaaaaacaaacaaaaaaaaaccaaaaacaaaccaaaaaaaaaaaaaacccacaaaatcaaacaaaccaaaaaaccagtcgcgagccagacctcagcgtgctcaccctcactgctacgacgccaaataaaaaccccagccaggggcggagaagcctccagcaggtcagacctcatgccaccgagccctggctgtgggaccaacccccaaccctgcctcccccgtgggggctacagaaggaaaaagagaagatgccagcttcctaatcccagcccccagccctgggccagcgaagacagggcacagcctgggcagatgggctggggcttagcaccacccaccaaatgttcttttccagaaggtgaaagagaaagggcctgaacaaccttacaccaaatattcagtagcttcatccaaaggatgtacagaatttttagcattgtgctcaacagaatgtgtccctaccatgtgtccccttctcccctggcccccagctctccccacctgggcagggggtcttgctttaacctcctccctccccccagcaggggagagttcaagggaaggcctgcggacaacttttcatcccctgttcctccctcttttcccctttgaagggtgggctaggccattttgccaagttctagctctcacaagtccctcctcaaccctgtcaccctcctctgctctggaactgactccctccccagcctatgggaaggtggaaatttcaggcaagaggggatgaagacattcagttgagggcattcagttgtctttttccatcctgtctgtttccctgaaaaaaaaaaaaattcatattccagtgcctatccgtgggatccttcacgttctttgacattaaccagaaaccaaaaagagaactcacctcgcttttcccaccctgtgcccctctggtactggcgaatgcctctccctccccccacatgcacgcacgcacacaccccagtggtggggttcctcgagatggcatccccatcagggtccatgtggtggggacagtgccacagcctgtggtccccatctgagagggcgcggtggtggccaccactcccacaagacctccacaactcttggctggaccctgtgtttgaccagccccggacacgtctccactgacgacggacagaggagagacaccactgggagccaccctgccctcctgctattgtggaggccaacaaagttttgaaccgaaaaccaaaaaaacagaaacaaacaaacaataaatttaaactagaaaaaaaatttatatatatatataaacatatatatatatatatatataaaagggaaagaagatgaggactcttcaagaataagatggaaccgcgaggcggagccaagcccctgcaccggtggtccaggcccttgttccccaaggcggatggaaggacggatgcttctttctcttcacaaatacctcatggacgttgtctttgggaaagccggagggggcggctggggcagggcctgtccctcggccagggcagatggaagcgggtgggcggggctgagagagggtatcagggacaggggtgaagagccccaaactcccctcccaaatcaactgaaaaagctttaaaaaaagacaggaaaaaaaggagtaagaaagcaaaaagaacagatgaaggaaaacttaacaacttttgggtggtttgattcctcctttgatttctttttcggttctcttttgtctgacctctctcctcccctccttcctctctcctcccctccttcctctctcctctcctccttcctgtctcctctctctccctttgctctcctctcttctctctcaatcttgttctttctgtgtctctcctcaaaccaaagtgttgcagtgaaggacacgagccattgaaatcagggtggggcctgacagccgtagtgtggcccctgccccttgttgggcaggagcagagagagaggagagccctgagaccgcagggctttggcctgggcagcttccactttctgccggacactctgaggagaggcagatggagctccaggcctcagcgttctcttttttccttgtctcccttctcccacccgggaaatgaaactgttgggctgggcgacggaggcagcagagactcggccattgcaggggcctctgggtgccttgtccgggcagtggtgaagtagccgcccctcccaccccggcacgatggggcctggcacctcgtctacccaacctcaccggaatgtaagcatctccgctgaacgactccctgcccttaccctacctctgagtttgtccatgtttatttcctgaagagagaagggactggcaagagggcttgggccccagcccaagggtggagagggggccaagggctcctgaccaaataggaaggacatttgagcagagcaaaatgaaaggaattacaaccaaaaaccccctccgagaagacaggcagcatggaaggcatggtggagatgactcaaacaaaaactatgattctagaccaaaaaggaaaaaaaaaaaaaaaaaaggaaagaaaatccaggactcaccaccacccacttcatcctgcttcctccccatcaagtcccaccacctgggacctctccccaccccagtatgtgggagtggggtaaagaggagaggaggagcagggggcagggatggggcagatgccctgatgttggtggagggacccctgtgcagccgggggtgctggggaccctccccatccaaccctcacacctaggaaaagaaaaacaagaaaaaaaaattcctgggagggggaaaaataaccaaatcccaagctttaactacagctgtgaaaccaaatattgggaagggggtaggagggagggaggggcaggtgagccccaggtctccccctgggcccccctcccctgaggactcgagataaggcaccaaatacctcatagaactttaatgttaaaaaaaggaaaccaaatatcgttggctgggggccagccagggcaaggggctggggggctggagggagccagggttgggaaggtgatgggggaattcatgccccccacccccatctgccccttacactctggtcccccgtctcgactccgggaaacaaaactatctcatcgtttttattttgtggtctgtacagagcctgtgtccgtgtgtctgtgtatgagcgagagagttggagggctggggagctttatgtgggggatggggagggcaaccccaggctaggctatgggctaggttagatgtccgaggttgggggccaagggcctgggctagaaagagaggagagatgagtgggttggagcagtggggagccctctgaatttctcttctccccaaccctgacctcctacttaagggagggacagagactgggtctaccctaatggtgggccttttcattgtgccaaaaaaaaaaaaaaaaaaattgatgccagtaactaaaccacctctctctgttctcttctggggggtggggtgggtgtgtgtgtgggggtgggtagggatggggaacccaagccccagtaggagttggggctgagatcaggaggaggggaaggatatgagttttccatccatctccctggagaaggccatgacgggctctccaagccctggggagatctggcgagggactagccaagtcagggtgacctcttgacctgactagtttttctaacccacatgaacaccagggtgcctctctcttcctctagcccagggtagggggacctgagtgagagagagagtgagacagacagcaagattgagacacgcgggcccccactggtctctgagtgggaaaggcaagtgcgagagataaaggcctccaagagaaaaaagaaacaaaccaaagatttaaccatttaaaaaaaaaaaaaaacccacagacaactccgctacctttttatatgttggaaaaaaagtgaaaaaaaattaaaaataaaaataaaaaaaaatacacaaaaactccaagccgcaagtccttcatgcggtttaaactttgacctcagcagtctccaaagcaagacgacgatgacaaaggcggaaacaaagaaaaaataatgtatatttttaagtatttgtccttgaattgttagctccttgttaaacaaacaaaaggagagaaaaatccagagagaagtgttgctgggatggagacaactatttactatgtctgtgacccctcccttctgcctccctccccttcctctctttcctgtcctctatccttgctgcccctcccccaatatgtcccccaaacccaggggctcagtatttatttatttatataattgcagggtgactgggggcctctctcggcaactcgtagagagcctttggataatggcagggtggggaatgggcgaggagtctttgggaagagcaggggcctgaactttcaactcctttctggcctcttgtcccactgcttccaccatcaccttccaaatccagggctgcactagggcaaggtgaccaccctacttggtaaagacctgattggcgcagcccattctggtgtgggtgtctttcaccacccagaatgaccaggttggaatgggggtgggtgaagttggagggggtggcaagtacaaggcaagggtgcccaggaaccggcatccagaaatcagccctggagtagacctgcctttcctccatccttaccaagttagcctccctttcagttccgtctgacccctgtgttggtagccccttccttcccttcctgtaccccctccgtctcttctcgtggtagcgggttagtgtttcagtgttcttaactccaatctgcttgttcattgtacaatgtgcttcttttaaggccccatttttgtaacttgagtgtgtcattcatctgaacaacaaacatcaaaaaataaaaaattaaaaactgtacagagagaaatgaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:5452 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IEA
GeneID:5452 -> Molecular function: GO:0019904 [protein domain specific binding] evidence: IEA
GeneID:5452 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IDA
GeneID:5452 -> Biological process: GO:0002335 [mature B cell differentiation] evidence: IEA
GeneID:5452 -> Biological process: GO:0002380 [immunoglobulin secretion involved in immune response] evidence: IEA
GeneID:5452 -> Biological process: GO:0006366 [transcription from RNA polymerase II promoter] evidence: TAS
GeneID:5452 -> Biological process: GO:0006959 [humoral immune response] evidence: TAS
GeneID:5452 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: IEA
GeneID:5452 -> Biological process: GO:0048469 [cell maturation] evidence: IEA
GeneID:5452 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:5452 -> Cellular component: GO:0005737 [cytoplasm] evidence: IEA
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