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2020-10-24 07:29:38, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_002526               4086 bp    mRNA    linear   PRI 19-MAY-2013
DEFINITION  Homo sapiens 5'-nucleotidase, ecto (CD73) (NT5E), transcript
            variant 1, mRNA.
ACCESSION   NM_002526
VERSION     NM_002526.3  GI:325651882
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4086)
  AUTHORS   Ohta,M., Toyama,K., Gutterman,D.D., Campbell,W.B., Lemaitre,V.,
            Teraoka,R. and Miura,H.
  TITLE     Ecto-5'-nucleotidase, CD73, is an endothelium-derived
            hyperpolarizing factor synthase
  JOURNAL   Arterioscler. Thromb. Vasc. Biol. 33 (3), 629-636 (2013)
   PUBMED   23288168
  REMARK    GeneRIF: Coronary vasodilation to adenine nucleotides is associated
            with endothelial CD73-dependent production of extracellular
            adenosine that acts as an endothelium-derived hyperpolarizing
            factor.
REFERENCE   2  (bases 1 to 4086)
  AUTHORS   Knapp,K., Zebisch,M., Pippel,J., El-Tayeb,A., Muller,C.E. and
            Strater,N.
  TITLE     Crystal structure of the human ecto-5'-nucleotidase (CD73):
            insights into the regulation of purinergic signaling
  JOURNAL   Structure 20 (12), 2161-2173 (2012)
   PUBMED   23142347
  REMARK    GeneRIF: Crystal structures of the dimeric human e5NT reveal an
            extensive conformational switch between the open and closed forms
            of the enzyme.
REFERENCE   3  (bases 1 to 4086)
  AUTHORS   Knapp,K.M., Zebisch,M. and Strater,N.
  TITLE     Crystallization and preliminary X-ray analysis of the open form of
            human ecto-5'-nucleotidase (CD73)
  JOURNAL   Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 68 (PT 12),
            1545-1549 (2012)
   PUBMED   23192044
  REMARK    GeneRIF: crystallization and preliminary X-ray crystallographic
            analysis of an open structural conformation of human e5NT are
            described.
REFERENCE   4  (bases 1 to 4086)
  AUTHORS   Nitschke,Y. and Rutsch,F.
  TITLE     Genetics in arterial calcification: lessons learned from rare
            diseases
  JOURNAL   Trends Cardiovasc. Med. 22 (6), 145-149 (2012)
   PUBMED   23122642
  REMARK    GeneRIF: Mutations in the underlying disease genes ENPP1, ABCC6,
            NT5E, and SLC20A2, respectively, lead to arterial media
            calcification.
            Review article
REFERENCE   5  (bases 1 to 4086)
  AUTHORS   Hansen,K.R., Resta,R., Webb,C.F. and Thompson,L.F.
  TITLE     Isolation and characterization of the promoter of the human
            5'-nucleotidase (CD73)-encoding gene
  JOURNAL   Gene 167 (1-2), 307-312 (1995)
   PUBMED   8566797
REFERENCE   6  (bases 1 to 4086)
  AUTHORS   Klemens,M.R., Sherman,W.R., Holmberg,N.J., Ruedi,J.M., Low,M.G. and
            Thompson,L.F.
  TITLE     Characterization of soluble vs membrane-bound human placental
            5'-nucleotidase
  JOURNAL   Biochem. Biophys. Res. Commun. 172 (3), 1371-1377 (1990)
   PUBMED   2173922
REFERENCE   7  (bases 1 to 4086)
  AUTHORS   Misumi,Y., Ogata,S., Ohkubo,K., Hirose,S. and Ikehara,Y.
  TITLE     Primary structure of human placental 5'-nucleotidase and
            identification of the glycolipid anchor in the mature form
  JOURNAL   Eur. J. Biochem. 191 (3), 563-569 (1990)
   PUBMED   2129526
REFERENCE   8  (bases 1 to 4086)
  AUTHORS   Thomson,L.F., Ruedi,J.M., Glass,A., Moldenhauer,G., Moller,P.,
            Low,M.G., Klemens,M.R., Massaia,M. and Lucas,A.H.
  TITLE     Production and characterization of monoclonal antibodies to the
            glycosyl phosphatidylinositol-anchored lymphocyte differentiation
            antigen ecto-5'-nucleotidase (CD73)
  JOURNAL   Tissue Antigens 35 (1), 9-19 (1990)
   PUBMED   2137649
REFERENCE   9  (bases 1 to 4086)
  AUTHORS   Boyle,J.M., Hey,Y., Guerts van Kessel,A. and Fox,M.
  TITLE     Assignment of ecto-5'-nucleotidase to human chromosome 6
  JOURNAL   Hum. Genet. 81 (1), 88-92 (1988)
   PUBMED   2848759
REFERENCE   10 (bases 1 to 4086)
  AUTHORS   Stefanovic,V., Mandel,P. and Rosenberg,A.
  TITLE     Ecto-5'-nucleotidase of intact cultured C6 rat glioma cells
  JOURNAL   J. Biol. Chem. 251 (13), 3900-3905 (1976)
   PUBMED   819433
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA574510.1, X55740.1,
            BC065937.1, AK075008.1 and BQ019358.1.
            This sequence is a reference standard in the RefSeqGene project.
            On Mar 10, 2011 this sequence version replaced gi:187131235.
            
            Summary: The protein encoded by this gene is a plasma membrane
            protein that catalyzes the conversion of extracellular nucleotides
            to membrane-permeable nucleosides. The encoded protein is used as a
            determinant of lymphocyte differentiation. Defects in this gene can
            lead to the calcification of joints and arteries. Two transcript
            variants encoding different isoforms have been found for this
            gene.[provided by RefSeq, Mar 2011].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X55740.1, BC065937.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025082 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-507               DA574510.1         1-507
            508-3069            X55740.1           1-2562
            3070-3219           BC065937.1         2539-2688
            3220-3834           X55740.1           2712-3326
            3835-4059           AK075008.1         3160-3384
            4060-4086           BQ019358.1         1-27                c
FEATURES             Location/Qualifiers
     source          1..4086
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q14-q21"
     gene            1..4086
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /note="5'-nucleotidase, ecto (CD73)"
                     /db_xref="GeneID:4907"
                     /db_xref="HGNC:8021"
                     /db_xref="HPRD:00552"
                     /db_xref="MIM:129190"
     exon            1..895
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /inference="alignment:Splign:1.39.8"
     variation       75
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:6919558"
     variation       140
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150152774"
     variation       161
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2295890"
     variation       464
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376344036"
     variation       472
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:184283916"
     variation       478
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189229964"
     misc_feature    485..487
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /note="upstream in-frame stop codon"
     CDS             557..2281
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /EC_number="3.1.3.5"
                     /note="isoform 1 preproprotein is encoded by transcript
                     variant 1; Purine 5-Prime-Nucleotidase;
                     ecto-5'-nucleotidase; 5'-NT"
                     /codon_start=1
                     /product="5'-nucleotidase isoform 1 preproprotein"
                     /protein_id="NP_002517.1"
                     /db_xref="GI:4505467"
                     /db_xref="CCDS:CCDS5002.1"
                     /db_xref="GeneID:4907"
                     /db_xref="HGNC:8021"
                     /db_xref="HPRD:00552"
                     /db_xref="MIM:129190"
                     /translation="
MCPRAARAPATLLLALGAVLWPAAGAWELTILHTNDVHSRLEQTSEDSSKCVNASRCMGGVARLFTKVQQIRRAEPNVLLLDAGDQYQGTIWFTVYKGAEVAHFMNALRYDAMALGNHEFDNGVEGLIEPLLKEAKFPILSANIKAKGPLASQISGLYLPYKVLPVGDEVVGIVGYTSKETPFLSNPGTNLVFEDEITALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDVVVGGHSNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKIEFDERGNVISSHGNPILLNSSIPEDPSIKADINKWRIKLDNYSTQELGKTIVYLDGSSQSCRFRECNMGNLICDAMINNNLRHTDEMFWNHVSMCILNGGGIRSPIDERNNGTITWENLAAVLPFGGTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDLSRKPGDRVVKLDVLCTKCRVPSYDPLKMDEVYKVILPNFLANGGDGFQMIKDELLRHDSGDQDINVVSTYISKMKVIYPAVEGRIKFSTGSHCHGSFSLIFLSLWAVIFVLYQ
"
     sig_peptide     557..634
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
     proprotein      635..2278
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /product="5'-nucleotidase isoform 1 proprotein"
     mat_peptide     635..2203
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /product="5'-nucleotidase isoform 1"
     misc_feature    638..2152
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /note="5'-nucleotidase/2',3'-cyclic phosphodiesterase and
                     related esterases [Nucleotide transport and metabolism];
                     Region: UshA; COG0737"
                     /db_xref="CDD:31080"
     misc_feature    641..1486
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /note="CD73 ecto-5'-nucleotidase and related proteins,
                     N-terminal metallophosphatase domain; Region: MPP_CD73_N;
                     cd07409"
                     /db_xref="CDD:163652"
     misc_feature    order(662..664,668..670,809..811,905..910,917..919,
                     1106..1108,1214..1216,1283..1285,1289..1291)
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /note="active site"
                     /db_xref="CDD:163652"
     misc_feature    order(662..664,668..670,809..811,905..907,1214..1216,
                     1283..1285,1289..1291)
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:163652"
     misc_feature    1592..2083
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /note="5'-nucleotidase, C-terminal domain; Region:
                     5_nucleotid_C; pfam02872"
                     /db_xref="CDD:202440"
     misc_feature    2201..2203
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="glycosyl phosphatidyl inositol (gpi) site; modified
                     site"
                     /citation=[7]
     variation       557
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202207703"
     variation       598
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368613430"
     variation       620
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:372252780"
     variation       632
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201419844"
     variation       658
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142909102"
     variation       664
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368729244"
     variation       685
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371172793"
     variation       697
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369010777"
     variation       714
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374757389"
     variation       723
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369193143"
     variation       740
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200250022"
     variation       778
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:147423946"
     variation       779
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:138139831"
     variation       882
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:375481678"
     exon            896..1118
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /inference="alignment:Splign:1.39.8"
     variation       898
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35694460"
     variation       935
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147283805"
     variation       943
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148743555"
     variation       956
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200207416"
     variation       1000
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142302523"
     variation       1013
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200369370"
     variation       1084
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:74858361"
     variation       1098
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:199573247"
     variation       1111
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376172369"
     exon            1119..1307
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /inference="alignment:Splign:1.39.8"
     variation       1161
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201534865"
     variation       1218
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:373328681"
     variation       1219
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139237444"
     variation       1238
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144535109"
     variation       1255
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146630544"
     variation       1258
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:141370047"
     variation       1259
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200664520"
     variation       1271
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200840390"
     variation       1274
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201657741"
     variation       1294
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143793168"
     exon            1308..1505
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /inference="alignment:Splign:1.39.8"
     variation       1331
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376792488"
     variation       1361
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:184831134"
     variation       1388
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41271617"
     variation       1399
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370583260"
     variation       1432
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149061664"
     variation       1453
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:35478984"
     variation       1454
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148199616"
     variation       1460
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:368274173"
     variation       1479
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201782026"
     variation       1480
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141102470"
     variation       1496
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371640203"
     exon            1506..1660
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /inference="alignment:Splign:1.39.8"
     variation       1535
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147019457"
     variation       1567
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374712948"
     variation       1594
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138198374"
     variation       1597
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2229522"
     variation       1616
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200648774"
     variation       1629
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:387906620"
     variation       1650
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:143679828"
     exon            1661..1766
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /inference="alignment:Splign:1.39.8"
     variation       1672
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200094485"
     variation       1682
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2229523"
     variation       1684
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138566130"
     variation       1692
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2229524"
     variation       1705
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370951693"
     variation       1706
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375139069"
     variation       1757
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144719925"
     variation       1758
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:139549986"
     variation       1763
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:138876213"
     exon            1767..1916
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /inference="alignment:Splign:1.39.8"
     variation       1776
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376406036"
     variation       1777
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:146166792"
     variation       1809
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146054415"
     variation       1815
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370017735"
     variation       1818
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:72905321"
     variation       1864
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370536110"
     variation       1878
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377417331"
     variation       1882
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368679446"
     variation       1883
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373069568"
     variation       1901
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376616753"
     variation       1912
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140182435"
     exon            1917..2117
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /inference="alignment:Splign:1.39.8"
     variation       1944
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201008460"
     variation       1964
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142656691"
     variation       2027
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143859595"
     variation       2034
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151304292"
     variation       2056
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376526362"
     variation       2059
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139343924"
     variation       2095
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150989796"
     variation       2098
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:145505137"
     variation       2108
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141170507"
     exon            2118..4068
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /inference="alignment:Splign:1.39.8"
     variation       2134
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202181475"
     variation       2144
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34160251"
     variation       2190
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371449832"
     variation       2205
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368609058"
     variation       2217
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372698120"
     variation       2328
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:193222810"
     STS             2355..2464
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /standard_name="D6S1847"
                     /db_xref="UniSTS:38875"
     variation       2511
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183777053"
     variation       2522
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:6913634"
     variation       2708
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:74562712"
     variation       2714
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201230877"
     variation       2720..2721
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:370566669"
     variation       2721
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:371699211"
     variation       2814
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:189184673"
     variation       2892
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:137869371"
     variation       2945
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:192272181"
     variation       3036
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184664228"
     variation       3162
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149223779"
     variation       3190
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188358257"
     variation       3204
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:112874886"
     variation       3216..3220
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace=""
                     /replace="ttatt"
                     /db_xref="dbSNP:139107209"
     variation       3220..3224
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace=""
                     /replace="tttat"
                     /db_xref="dbSNP:58177677"
     STS             3227..3525
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /standard_name="WI-20546"
                     /db_xref="UniSTS:46296"
     variation       3307
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:80260534"
     variation       3329
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375798700"
     variation       3449
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:143368737"
     variation       3466
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:148352610"
     variation       3477
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141542163"
     variation       3516
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:191717024"
     variation       3572
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370052880"
     variation       3595
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:41271621"
     STS             3649..3815
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /standard_name="STS-X55740"
                     /db_xref="UniSTS:73678"
     variation       3882
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:6922"
     variation       3892
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:150877880"
     STS             3904..4026
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /standard_name="RH46710"
                     /db_xref="UniSTS:21108"
     variation       3934
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138351627"
     variation       3950
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:142840005"
     polyA_signal    4041..4046
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
     polyA_site      4068
                     /gene="NT5E"
                     /gene_synonym="CD73; E5NT; eN; eNT; NT; NT5; NTE"
ORIGIN      
actcctcctctctgcccctcagctcgctcatctttcttcccgccccctctcttttccttctttggttctttgaagtgatgagctagcgcaaccacaaaccatacattccttttgtagaaaaacccgtgcctcgaatgaggcgagactcagagaggacccaggcgcggggcggacccctccaattccttcctcgcgcccccgaaagagcggcgcaccagcagccgaactgccggcgcccaggctccctggtccggccgggatgcggccggtacccgctccccgccgggaacaacctctccactcttcctgcagggagctggtgccagccgacagccgcgccagggccgctccgggtaccagggtcggatcgggtgacgtcgcgaacttgcgcctggccgccaagccggcctccaggctgaagaaggacccgccccggccttgacccgggccccgcccctccagccggggcaccgagccccggccctagctgctcgcccctactcgccggcactcgcccggctcgcccgctttcgcacccagttcacgcgccacagctatgtgtccccgagccgcgcgggcgcccgcgacgctactcctcgccctgggcgcggtgctgtggcctgcggctggcgcctgggagcttacgattttgcacaccaacgacgtgcacagccggctggagcagaccagcgaggactccagcaagtgcgtcaacgccagccgctgcatgggtggcgtggctcggctcttcaccaaggttcagcagatccgccgcgccgaacccaacgtgctgctgctggacgccggcgaccagtaccagggcactatctggttcaccgtgtacaagggcgccgaggtggcgcacttcatgaacgccctgcgctacgatgccatggcactgggaaatcatgaatttgataatggtgtggaaggactgatcgagccactcctcaaagaggccaaatttccaattctgagtgcaaacattaaagcaaaggggccactagcatctcaaatatcaggactttatttgccatataaagttcttcctgttggtgatgaagttgtgggaatcgttggatacacttccaaagaaaccccttttctctcaaatccagggacaaatttagtgtttgaagatgaaatcactgcattacaacctgaagtagataagttaaaaactctaaatgtgaacaaaattattgcactgggacattcgggttttgaaatggataaactcatcgctcagaaagtgaggggtgtggacgtcgtggtgggaggacactccaacacatttctttacacaggcaatccaccttccaaagaggtgcctgctgggaagtacccattcatagtcacttctgatgatgggcggaaggttcctgtagtccaggcctatgcttttggcaaatacctaggctatctgaagatcgagtttgatgaaagaggaaacgtcatctcttcccatggaaatcccattcttctaaacagcagcattcctgaagatccaagcataaaagcagacattaacaaatggaggataaaattggataattattctacccaggaattagggaaaacaattgtctatctggatggctcctctcaatcatgccgctttagagaatgcaacatgggcaacctgatttgtgatgcaatgattaacaacaacctgagacacacggatgaaatgttctggaaccacgtatccatgtgcattttaaatggaggtggtatccggtcgcccattgatgaacgcaacaatggcacaattacctgggagaacctggctgctgtattgccctttggaggcacatttgacctagtccagttaaaaggttccaccctgaagaaggcctttgagcatagcgtgcaccgctacggccagtccactggagagttcctgcaggtgggcggaatccatgtggtgtatgatctttcccgaaaacctggagacagagtagtcaaattagatgttctttgcaccaagtgtcgagtgcccagttatgaccctctcaaaatggacgaggtatataaggtgatcctcccaaacttcctggccaatggtggagatgggttccagatgataaaagatgaattattaagacatgactctggtgaccaagatatcaacgtggtttctacatatatctccaaaatgaaagtaatttatccagcagttgaaggtcggatcaagttttccacaggaagtcactgccatggaagcttttctttaatatttctttcactttgggcagtgatctttgttttataccaatagccaaaaattctccttgcctttaatgtgtgaaactgcattttttcaagtgagattcaaatctgccttttaggacctggctttgtgacagcaaaaaccatctttacaggctcctagaagctgaaggttagagcattataaaatgaagagacagacatgattactcagggtcagcaacctagtgagttagaaaaaaaattaacatagggccctataaggagaaagccaactatgttaagtttacgtgtccaaattttaatgaaattttactaacaattttaaaccatatttttcttcttcatatccatttctaatccatcaaacagcttatgtttacataaaattttatcattcacaaggaagttttaagcacactgtctcatttgatatccacaacttatttttggtaggaaagagagatgtttttcccacctgtcagatgaaaaaactgaagctcaaaaagggttgacttgaccatacagctaatgctgacagatccaagacctagacctaggtcttttgaactcaagtccagcattctcaactatatcaagttactgttcagaatacttaatatctcctctcttcataattatcaatagccccaagctcatggatgacaaatctctgctttatttcttgtctctattttttcactttatagctcctgttataatagcaagtttaatggtataaacacaggataccatcctctcttgcaacacccatgtgcctttgatgagtcaggtagcaagctgtagtagataatgagaaaggccagaggctgcaaaagacagtcaaaggacacgagagaaaggaaggggaagaacaggactccaggactgttttatattatagaaaagcaagagctaaagagcatttacacatgttaaacagatacttgttaagcatagtgcctgacacacggcattagctgttattttatgagattccatcagctctgcctctgtcctctttcttctaacatgaaggtatcatgagaagagaaccttctaacataagctgtaattctaaacctgcacttgtccctctccagcaagaggctagcactgaattcattctactcatactacacacccagttatggaatgtccagagttctcgaagaaaataaatgactttaggaagaggtatacattttttaagtcgctctgcctccaaatctgaacagtcactgtaaatcattcttaagcccagatatgagaacttctgctggaaagtgggaccctctgagtgggtggtcagaaaatacccatgctgatgaaatgacctatgcccaaagaacaaatacttaacgtgggagtggaaccacatgagcctgctcagctctgcataagtaattcaagaaatgggaggcttcaccttaaaaacagtgtgcaaatggcagctagaggttttgataggaagtatgtttgtttcttagtgtttacaaatattaagtactcttgatacaaaatatacttttaaacttcataacctttttataaaagttgttgcagcaaaataatagcctcggttctatgcatatatggattagctataaaaaatgtcaataagattgtacaaggaaaattagagaaagtcacatttagggtttattttttacacttggccagtaaaatagggtaaatcctattagaattttttaaagaactttttttaagtttcctaaatctgtgtgtgtattgtgaagtggtataagaaatgactttgaaccactttgcaattgtagattcccaacaataaaattgaagataagctctttggtcaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:4907 -> Molecular function: GO:0000166 [nucleotide binding] evidence: IEA
            GeneID:4907 -> Molecular function: GO:0008253 [5'-nucleotidase activity] evidence: EXP
            GeneID:4907 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA
            GeneID:4907 -> Biological process: GO:0006144 [purine nucleobase metabolic process] evidence: TAS
            GeneID:4907 -> Biological process: GO:0006195 [purine nucleotide catabolic process] evidence: TAS
            GeneID:4907 -> Biological process: GO:0006196 [AMP catabolic process] evidence: IEA
            GeneID:4907 -> Biological process: GO:0006206 [pyrimidine nucleobase metabolic process] evidence: TAS
            GeneID:4907 -> Biological process: GO:0006259 [DNA metabolic process] evidence: TAS
            GeneID:4907 -> Biological process: GO:0044281 [small molecule metabolic process] evidence: TAS
            GeneID:4907 -> Biological process: GO:0046086 [adenosine biosynthetic process] evidence: IEA
            GeneID:4907 -> Biological process: GO:0046135 [pyrimidine nucleoside catabolic process] evidence: TAS
            GeneID:4907 -> Biological process: GO:0050728 [negative regulation of inflammatory response] evidence: IEA
            GeneID:4907 -> Biological process: GO:0055086 [nucleobase-containing small molecule metabolic process] evidence: TAS
            GeneID:4907 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:4907 -> Cellular component: GO:0005886 [plasma membrane] evidence: IDA
            GeneID:4907 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS
            GeneID:4907 -> Cellular component: GO:0016020 [membrane] evidence: TAS
            GeneID:4907 -> Cellular component: GO:0031225 [anchored to membrane] evidence: IEA
            GeneID:4907 -> Cellular component: GO:0070062 [extracellular vesicular exosome] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_002517 -> EC 3.1.3.5

by @meso_cacase at DBCLS
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