LOCUS       NM_002316               5783 bp    mRNA    linear   PRI 15-JUN-2013
DEFINITION  Homo sapiens LIM homeobox transcription factor 1, beta (LMX1B),
            transcript variant 1, mRNA.
ACCESSION   NM_002316
VERSION     NM_002316.3  GI:292494910
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5783)
  AUTHORS   Zhou,T.B. and Qin,Y.H.
  TITLE     The signaling pathways of LMX1B and its role in glomerulosclerosis
  JOURNAL   J. Recept. Signal Transduct. Res. 32 (6), 285-289 (2012)
   PUBMED   23046462
  REMARK    GeneRIF: LMX1B is important in regulating type IV collagen gene
            expression in the GBM of the developing kidney and also has a
            likely role in regulating additional genes important in podocyte
            function and maintenance
            Review article
REFERENCE   2  (bases 1 to 5783)
  AUTHORS   Thanseem,I., Nakamura,K., Anitha,A., Suda,S., Yamada,K.,
            Iwayama,Y., Toyota,T., Tsujii,M., Iwata,Y., Suzuki,K.,
            Matsuzaki,H., Iwata,K., Sugiyama,T., Yoshikawa,T. and Mori,N.
  TITLE     Association of transcription factor gene LMX1B with autism
  JOURNAL   PLoS ONE 6 (8), E23738 (2011)
   PUBMED   21901133
  REMARK    GeneRIF: Data report on the association of LMX1B with autism,
            though it should be viewed with some caution considering the modest
            associations we report.
REFERENCE   3  (bases 1 to 5783)
  AUTHORS   Romero,P., Sanhueza,F., Lopez,P., Reyes,L. and Herrera,L.
  TITLE     c.194 A>C (Q65P) mutation in the LMX1B gene in patients with
            nail-patella syndrome associated with glaucoma
  JOURNAL   Mol. Vis. 17, 1929-1939 (2011)
   PUBMED   21850167
  REMARK    GeneRIF: c.194 A>C (Q65P) mutation is present in the LMX1B gene of
            the Chilean patients with nail-patella syndrome associated with
            glaucoma.
REFERENCE   4  (bases 1 to 5783)
  AUTHORS   Song,N.N., Xiu,J.B., Huang,Y., Chen,J.Y., Zhang,L., Gutknecht,L.,
            Lesch,K.P., Li,H. and Ding,Y.Q.
  TITLE     Adult raphe-specific deletion of Lmx1b leads to central serotonin
            deficiency
  JOURNAL   PLoS ONE 6 (1), E15998 (2011)
   PUBMED   21246047
  REMARK    GeneRIF: effect of lmx1b on gene expression regulation in the brain
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5783)
  AUTHORS   Dunston,J.A., Hamlington,J.D., Zaveri,J., Sweeney,E., Sibbring,J.,
            Tran,C., Malbroux,M., O'Neill,J.P., Mountford,R. and McIntosh,I.
  TITLE     The human LMX1B gene: transcription unit, promoter, and pathogenic
            mutations
  JOURNAL   Genomics 84 (3), 565-576 (2004)
   PUBMED   15498463
REFERENCE   6  (bases 1 to 5783)
  AUTHORS   Vollrath,D., Jaramillo-Babb,V.L., Clough,M.V., McIntosh,I.,
            Scott,K.M., Lichter,P.R. and Richards,J.E.
  TITLE     Loss-of-function mutations in the LIM-homeodomain gene, LMX1B, in
            nail-patella syndrome
  JOURNAL   Hum. Mol. Genet. 7 (7), 1091-1098 (1998)
   PUBMED   9618165
  REMARK    Erratum:[Hum Mol Genet 1998 Aug;7(8):1333]
REFERENCE   7  (bases 1 to 5783)
  AUTHORS   Chen,H., Lun,Y., Ovchinnikov,D., Kokubo,H., Oberg,K.C.,
            Pepicelli,C.V., Gan,L., Lee,B. and Johnson,R.L.
  TITLE     Limb and kidney defects in Lmx1b mutant mice suggest an involvement
            of LMX1B in human nail patella syndrome
  JOURNAL   Nat. Genet. 19 (1), 51-55 (1998)
   PUBMED   9590288
REFERENCE   8  (bases 1 to 5783)
  AUTHORS   Dreyer,S.D., Zhou,G., Baldini,A., Winterpacht,A., Zabel,B.,
            Cole,W., Johnson,R.L. and Lee,B.
  TITLE     Mutations in LMX1B cause abnormal skeletal patterning and renal
            dysplasia in nail patella syndrome
  JOURNAL   Nat. Genet. 19 (1), 47-50 (1998)
   PUBMED   9590287
REFERENCE   9  (bases 1 to 5783)
  AUTHORS   Iannotti,C.A., Inoue,H., Bernal,E., Aoki,M., Liu,L.,
            Donis-Keller,H., German,M.S. and Permutt,M.A.
  TITLE     Identification of a human LMX1 (LMX1.1)-related gene, LMX1.2:
            tissue-specific expression and linkage mapping on chromosome 9
  JOURNAL   Genomics 46 (3), 520-524 (1997)
   PUBMED   9441763
REFERENCE   10 (bases 1 to 5783)
  AUTHORS   Johnson,J.D., Zhang,W., Rudnick,A., Rutter,W.J. and German,M.S.
  TITLE     Transcriptional synergy between LIM-homeodomain proteins and basic
            helix-loop-helix proteins: the LIM2 domain determines specificity
  JOURNAL   Mol. Cell. Biol. 17 (7), 3488-3496 (1997)
   PUBMED   9199284
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL161908.13, BC113491.1,
            AL161731.20 and EL952935.1.
            This sequence is a reference standard in the RefSeqGene project.
            On Mar 30, 2010 this sequence version replaced gi:164565424.
            
            Summary: This gene encodes a member of LIM-homeodomain family of
            proteins containing two N-terminal zinc-binding LIM domains, 1
            homeodomain, and a C-terminal glutamine-rich domain. It functions
            as a transcription factor, and is essential for the normal
            development of dorsal limb structures, the glomerular basement
            membrane, the anterior segment of the eye, and dopaminergic and
            serotonergic neurons. Mutations in this gene are associated with
            nail-patella syndrome. Alternatively spliced transcript variants
            encoding different isoforms have been found for this gene.
            [provided by RefSeq, Mar 2010].
            
            Transcript Variant: This variant (1) represents the predominant
            transcript and encodes isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC113491.1, AF057135.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           ERS025088 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                AL161908.13        64452-64477
            27-1293             BC113491.1         1-1267
            1294-5393           AL161731.20        40443-44542
            5394-5783           EL952935.1         44-433
FEATURES             Location/Qualifiers
     source          1..5783
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q33.3"
     gene            1..5783
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="LIM homeobox transcription factor 1, beta"
                     /db_xref="GeneID:4010"
                     /db_xref="HGNC:6654"
                     /db_xref="MIM:602575"
     exon            1..146
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     CDS             8..1195
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     LMX-1.2; LIM/homeobox protein 1.2; LIM/homeobox protein
                     LMX1B"
                     /codon_start=1
                     /product="LIM homeobox transcription factor 1-beta isoform
                     1"
                     /protein_id="NP_002307.2"
                     /db_xref="GI:292494911"
                     /db_xref="CCDS:CCDS6866.2"
                     /db_xref="GeneID:4010"
                     /db_xref="HGNC:6654"
                     /db_xref="MIM:602575"
                     /translation="

MDIATGPESLERCFPRGQTDCAKMLDGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECLQCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQEVLSSRMEGMMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGNDSIFHDIDSDTSLTSLSDCFLGSSDVGSLQARVGNPIDRLYSMQSSYFAS

"
     misc_feature    173..331
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="The first LIM domain of Lmx1b; Region: LIM1_Lmx1b;
                     cd09371"
                     /db_xref="CDD:188757"
     misc_feature    order(173..175,182..184,236..238,245..247,254..256,
                     263..265,314..316,323..325)
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188757"
     misc_feature    350..514
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="The second LIM domain of Lmx1a and Lmx1b; Region:
                     LIM2_Lmx1a_Lmx1b; cd09378"
                     /db_xref="CDD:188764"
     misc_feature    order(350..352,359..361,416..418,425..427,434..436,
                     443..445,500..502,509..511)
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188764"
     misc_feature    677..835
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="Homeodomain;  DNA binding domains involved in the
                     transcriptional regulation of key eukaryotic developmental
                     processes; may bind to DNA as monomers or as homo- and/or
                     heterodimers, in a sequence-specific manner; Region:
                     homeodomain; cd00086"
                     /db_xref="CDD:238039"
     misc_feature    order(677..679,683..685,734..736,752..754,791..793,
                     797..802,809..814,818..826,830..835)
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(680..682,800..802,809..814,821..823)
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     STS             27..1293
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /db_xref="UniSTS:483257"
     variation       64
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376265443"
     STS             77..1195
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /db_xref="UniSTS:480873"
     variation       108
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:375095510"
     variation       123
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367661538"
     exon            147..333
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     variation       157
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148305192"
     variation       168
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371819068"
     variation       191
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371293980"
     variation       217
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:374685767"
     variation       231
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2235058"
     variation       251
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:121909489"
     variation       258
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377436751"
     variation       259
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2235059"
     variation       302
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:141391682"
     exon            334..566
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     variation       340
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138385790"
     variation       342
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370537843"
     variation       343
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144043214"
     variation       360
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:121909488"
     variation       373
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200350302"
     variation       376
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:147293594"
     variation       379
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374078636"
     variation       399
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373429181"
     variation       400
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:190161633"
     variation       439
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375657880"
     variation       448
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2277158"
     variation       458
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149434820"
     variation       514
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368298608"
     variation       515
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199738980"
     variation       541
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:116316477"
     variation       542
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181422024"
     variation       549
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:148403563"
     variation       550
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375486982"
     variation       553
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34434402"
     variation       559
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142488434"
     variation       565
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370299750"
     exon            567..748
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     variation       598
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146465341"
     variation       601
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139862413"
     variation       668
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:121909487"
     variation       673
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143407067"
     variation       675
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:121909491"
     variation       676
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146720578"
     variation       688
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147071667"
     variation       698
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:121909490"
     variation       730
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368736494"
     variation       733
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:13295990"
     exon            749..826
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     variation       752
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:121909492"
     variation       790
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371560611"
     variation       814
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:121909486"
     exon            827..893
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     exon            894..1037
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     variation       901
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373033856"
     variation       908
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376497496"
     variation       936
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369831428"
     variation       937
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112171815"
     variation       940
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:145052881"
     variation       989
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373336352"
     variation       1021
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199580468"
     exon            1038..5776
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /inference="alignment:Splign:1.39.8"
     variation       1045
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148940265"
     variation       1047
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147035553"
     variation       1092
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:76277667"
     variation       1093
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:10115304"
     variation       1094
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:78770531"
     variation       1118
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375881049"
     variation       1136
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367916653"
     variation       1137
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143906016"
     variation       1138
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146476348"
     variation       1150
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148356178"
     variation       1157
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141496559"
     variation       1159
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200484654"
     variation       1186
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372183654"
     variation       1208
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375458623"
     variation       1216
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369706326"
     variation       1222
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10115373"
     variation       1233
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201442685"
     variation       1234
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:376851692"
     variation       1235
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374778848"
     variation       1246
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10121481"
     variation       1274
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10115393"
     variation       1322
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113846301"
     variation       1350
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151191848"
     variation       1368
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181701033"
     variation       1449
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371380792"
     variation       1475
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111648919"
     variation       1633
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140325479"
     variation       1646
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:71497630"
     variation       1672
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374016635"
     variation       1710
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112375232"
     variation       1779
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:34200683"
     variation       1828..1831
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="acac"
                     /db_xref="dbSNP:147813553"
     variation       1876
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138360048"
     variation       1903
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10987413"
     variation       1943
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:10987414"
     variation       1980
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143919006"
     variation       2079
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146268507"
     variation       2093
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:10760450"
     variation       2127
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:28687510"
     variation       2130
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186360995"
     variation       2195
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:189691069"
     variation       2301..2302
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tt"
                     /db_xref="dbSNP:201556524"
     variation       2326
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138749439"
     variation       2345
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181187127"
     variation       2385
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374742119"
     variation       2435..2436
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tg"
                     /db_xref="dbSNP:368812241"
     variation       2435
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368887101"
     variation       2450
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:16929236"
     variation       2499
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:73596779"
     variation       2523
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185183718"
     variation       2582..2586
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tgttt"
                     /db_xref="dbSNP:67078890"
     variation       2582..2583
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="g"
                     /replace="tgttt"
                     /db_xref="dbSNP:72111206"
     variation       2584
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:13300385"
     variation       2584
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="gtttt"
                     /replace="ttttg"
                     /db_xref="dbSNP:71493852"
     variation       2587..2611
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tgttttgttttgttttgttttgttt"
                     /db_xref="dbSNP:370075271"
     variation       2588
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:200514771"
     variation       2588
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:13299451"
     variation       2632
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tgttt"
                     /db_xref="dbSNP:10581734"
     variation       2636..2637
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tgttt"
                     /db_xref="dbSNP:59836255"
     variation       2668
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:13299609"
     STS             2686..2895
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /standard_name="RH80030"
                     /db_xref="UniSTS:87680"
     variation       2689
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370649232"
     variation       2705
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189648333"
     variation       2714
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183329572"
     variation       2733
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:144857145"
     variation       2769
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:148173186"
     variation       2777
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10987415"
     variation       2799
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146126278"
     variation       2833..2853
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="ggtctccaacccccgacctca"
                     /db_xref="dbSNP:199608526"
     variation       2839
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:187256465"
     variation       2861
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:10987416"
     variation       2862
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375078942"
     variation       2868
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:191584459"
     variation       2898
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144070517"
     variation       2911
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116411474"
     variation       2955
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183486611"
     variation       2982
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372210078"
     variation       3187..3192
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="ccccaa"
                     /replace="tcccag"
                     /db_xref="dbSNP:71494050"
     variation       3187
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34776870"
     variation       3190
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:74498940"
     variation       3192
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:35632228"
     variation       3355
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145937520"
     variation       3379
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10733682"
     variation       3389..3390
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:149174535"
     variation       3540
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:74429080"
     variation       3580
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:35712948"
     variation       3588
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:10120414"
     variation       3589
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:10760451"
     variation       3626
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114971128"
     variation       3652
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188331536"
     variation       3658
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:373410299"
     variation       3728
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376612764"
     variation       3776
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370880644"
     variation       3782
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374778359"
     variation       3784..3785
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tt"
                     /db_xref="dbSNP:35559677"
     variation       3785
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:77350418"
     variation       3786
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="tt"
                     /db_xref="dbSNP:57949927"
     variation       3908
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139482215"
     variation       3909
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149740102"
     variation       3934
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:145602359"
     variation       4026
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148906444"
     variation       4161
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191951894"
     variation       4179
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:4083644"
     variation       4377
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3861878"
     variation       4443
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145190620"
     variation       4537
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:4083645"
     variation       4541
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:7023938"
     variation       4749
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182607285"
     variation       4754
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376141195"
     variation       4911
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:147614955"
     variation       4966
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:10987417"
     variation       5028
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10987418"
     variation       5059
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:10987419"
     variation       5060
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10987420"
     variation       5076
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:10987421"
     variation       5152
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:10987422"
     variation       5175
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:186932324"
     variation       5322
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146636393"
     variation       5324
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148294658"
     variation       5325
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140459665"
     variation       5352
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185290341"
     variation       5360
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:111940190"
     variation       5366
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:3814119"
     variation       5405
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374547564"
     variation       5483
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150407176"
     variation       5568
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:78565800"
     variation       5732
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:78799000"
     polyA_signal    5756..5761
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
     variation       5765..5766
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:35956748"
     polyA_site      5776
                     /gene="LMX1B"
                     /gene_synonym="LMX1.2; NPS1"
ORIGIN      

gcgtcccatggatatagcaacaggtcccgagtcgctggagaggtgcttccctcgcgggcagacggactgcgccaagatgttggacggcatcaagatggaggagcacgccctgcgccccgggcccgccactctgggggtgctgctgggctccgactgcccgcatcccgccgtctgcgagggctgccagcggcccatctccgaccgcttcctgatgcgagtcaacgagtcgtcctggcacgaggagtgtttgcagtgcgcggcgtgtcagcaagccctcaccaccagctgctacttccgggatcggaaactgtactgcaaacaagactaccaacagctcttcgcggccaagtgcagcggctgcatggagaagatcgcccccaccgagttcgtgatgcgggcgctggagtgcgtgtaccacctgggctgcttctgctgctgcgtgtgtgaacggcagctacgcaagggcgacgaattcgtgctcaaggagggccagctgctgtgcaagggtgactacgagaaggagaaggacctgctcagctccgtgagccccgacgagtccgactccgtgaagagcgaggatgaagatggggacatgaagccggccaaggggcagggcagtcagagcaagggcagcggggatgacgggaaggacccgcggaggcccaagcgaccccggaccatcctcaccacgcagcagcgaagagccttcaaggcctccttcgaggtctcgtcgaagccttgccgaaaggtccgagagacactggcagctgagacgggcctcagtgtgcgcgtggtccaggtctggtttcagaaccaaagagcaaagatgaagaagctggcgcggcggcaccagcagcagcaggagcagcagaactcccagcggctgggccaggaggtcctgtccagccgcatggagggcatgatggcttcctacacgccgctggccccaccacagcagcagatcgtggccatggaacagagcccctacggcagcagcgaccccttccagcagggcctcacgccgccccaaatgccagggaacgactccatcttccatgacatcgacagcgatacctccttaaccagcctcagcgactgcttcctcggctcctcagacgtgggctccctgcaggcccgcgtggggaaccccatcgaccggctctactccatgcagagttcctacttcgcctcctgagagccagccaggcgcacggacgcttgggcaggggcctgggggggactgccagcctctgcggccagcctggccacccccgccctgctctccgcacagactacagacagccatacggtgccctcccctcggccagctgggcctgaccactgtgcccgttgggtacagccagaccggtagatgggcacagcctgggcaggggctgtgtcctgcccacagagaccttgtcatccccagggacccagagctctcggacggccactcgcctcccagccccacctcggcctccatcgcctcctccccatctcttttttgggaagcttaaattctctctatttttttaaatgtcctctctgtgtccatggccctccatgcaagccccaggacaatggtgtcatgaggcggtgacctgagaagcgtgtgtacctgtgccccagcaagggcaggggtggcctctgggggcaggcccactgcctggaaccgcacacccctcagcctgagtctggagcagcagtggagaggggcctgaggggaggcactgtcaggaggcgggctcggagcctgagcctgggcaggcgcaaagggacagagaggcacgtgcagacacatgcacacttgcagacaaacccacgcaaacacacacacagctgtatggggacaccagaagggacagggatgctcagcgggtctgtcctgccttgtcagaaagagaaaaggaggccaggcaggggaccccccagttcttaagagcgattggaaagggaggaaggggagaggaagaggcgaacttgaagcatcggacccagttgtatcccagcctgggcccaaatgggggcagcctgggcagggagggcagccccaggccccaccaactctagaggcagatggagcccccagaaccaggtagcatcagaccagacaacagagcctccaggggtcagggacttcagaagcacctgctgggcaccccatctgcaatgtggtcctctccccagccacctctgcctcccctcacatacctccagtgacaaggagctcactaggtcagcgagcccacagcagctgtgctgtcctgcatcccagagccaggcttccccagctctccctcttaacactgtcccccagcaggcctccggctgtccctctaaaggtgtggggcaggtatcacttcaccttcccactgatgtcagccggccagaagtgagcaggcacatcacctctcctgctgtggcacccttcctctgttaatttggcccaaaagacaatgatttggccacatgaccttagagattcaccctgccctgctgtagctaaatccctgggccccacacgcaagtgacagctaagccacatctgttttctgtgtatatgcaggatgggggcacctactgttttgttttgttttgttttgttttgttttgttttgttttgttttgttttgtttgagacggagtttcgctcttgttgcccaggctggagtgcaatggcgcgatctcggctcaccacaacctccgcctcccaggttcaagtgattctgatgcctcagcctccctagtagctgagattacaggcatgcgccaccacacccagctaattttgtatttttagtagcaacggggtttctccatgttggtcaggctggtctccaacccccgacctcaggtgatccgcctgcctcggcctcccaaagtgctgggattacaggcgtgagccaccgcacccagtctgcacttactgtttagactgaatgagggaccgtgacctctttccttttccattccttcttactcgattcattccagcctgtggaatttctctgcaccctgattcagtgaccactgctctcctctctcccagcacatctgcccagtgaggagttggccctgggtctcacctgaggtgtgtggaccgggctggcctctccctgtttgacattggcccattaatgcatcctctttgggggacacattccaattgcatttcctgcccccttctcccagggcaattgcagaagattgtgtcaggcgccctgctggaagtcaggtgcactagatccatccccagccccagtctgctcaactctatccctgtcagagcaaggaggctgggctgctggggcctgactggtgagcccaccctgtcccctggtgatcactgtgtccccttgttcaggtgctcacaaccctacctttaactctgaggtcaagccctaggccaccaccctaaagtctgcctggtccaacctttgagcaagtaaggataatgaatgtcccttttccacctttggggccctctgcctggatctctggaatcctctaagttcaacctgttctgtggttttgctcccgtttgctgggaaattcagtccccccagaatgtcctgggccaacctccttgcctgacatgtggcctcgtgtcacccattgggccccagcagccagctagcccttctgcagctcttcttacaaacagagcctctccaaggacctcagttgatgttctggtccttctgccgcctcagcccaccagggtccgtgccaccatgggtctcttgagcagcagctgcactggcttctggagagacacccctctttctccttttgcacatgcaccatctgaatcgtgccagggacatcctgggcagattcaggggcagatgccctatcccccaggagacctggcccttctctctcagacccaataagttggaagggacgtcagaagcggtcatctcatctgccccttattttatagttggaaaccctgaggcaagagagggaaagaggcctgtccaaggtccgggttagtgacagagctgagctgagaacagggacgttgtgccccactgtcccctgtggtttgtgaatgacctccaggtcagggggtcacaacttgttcttagtaaacttgccagctgttggggtcacatattcccattctggggcctcacaaacccccgaatccagccgggaccccatgccaggagctggtctagggacagcatgcttgtgacccacagactgttaaagccagaagggacctcagagagtcccttatgctggaggcgccctgtcagccgtggctaggggccccttgctctatgctgtgccttgctgcccacaggctcccagacaccagtgcccactctgcccagccccggactgggtgtggctcgcagatgaacaagatgcagggcctgccttgaggggtgtctcctagaaggaaagccagactctccggcccagccagagagtccagacatggcagggacccgtttctcagatgaggagcctgaggctcagagaagggaggcgatgtgttcagggccacccagcagaagcctgtggggctgggcaaccttctcccactttatgggaggagctgcagccttggctgggagctgggcggggagtagccaggaccaccccttgcccgtgccgtgacatggaaccttcatcactaagggggctggagtgggaagagggagataactgtgtggtctccagagcaaaagagaatgagaggtgggcagggggagtcttggcaaaagaccaagttccacttccctgctggggaagtcaaggctcagaaagaggaaataattgccccaggtaacacagggcagaggagggacaaaaagctgggcatggccccagccagagcctcatctgcctactccgtgaagcctcccaggtactctgctatcctgggaaacgcacagggaggccacacagagacactgctcacaagagtcagaccaaggtgccagcacagcctggaaagagctcagaaagggggttggtgcacgtggctgggcatcttaggaggcttcctgagggtgggtaaaggtgggaaggccctggcgctgcatcagatgagcagggcctggcagggacaagcctcttctcctttgggaagccctgcagcctcctagcaagaggctgattccccactctgcccccatctgaatgtccttttcatgttgcacgcagggaacctcaggaaggaggattgcctgatgcctgcctggctccatccttgagctctgggcaccacctagggtgagggagagcctgcagctctggggctaagtctgccctggggggaaagggctccacgctcacacgcacgcgctcgcacacacacactcacacctggacgcacacggaggcttgcggacccatactcacaggcacatgtggcctggggactgggggagcaggaaagacccctccaacatttggcccttggaaggcaccattgccaatgagcctctttgctggttcccccgaccccacctgggggtcccatgggagcccagcccagccaggtgtggggatgggccaccggccattcctgttttccttgtacagacagattctcactacccacccgccatccccagacacattttatttaataacttgtcattgttaaattatttattagcgtttaccacaccaccacccccaccctgccctccactctcaccttccacctcttcccacaacagcagaaaatggaaacaacaacaaaaaaagatgagacatcagtatatttgtaaataaaccgacctgtacactcaaaaaaa

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:4010 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IDA
            GeneID:4010 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:4010 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA
            GeneID:4010 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA
            GeneID:4010 -> Biological process: GO:0001701 [in utero embryonic development] evidence: NAS
            GeneID:4010 -> Biological process: GO:0001764 [neuron migration] evidence: IEA
            GeneID:4010 -> Biological process: GO:0002930 [trabecular meshwork development] evidence: IEA
            GeneID:4010 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
            GeneID:4010 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IDA
            GeneID:4010 -> Biological process: GO:0007275 [multicellular organismal development] evidence: NAS
            GeneID:4010 -> Biological process: GO:0008219 [cell death] evidence: IEA
            GeneID:4010 -> Biological process: GO:0008283 [cell proliferation] evidence: IEA
            GeneID:4010 -> Biological process: GO:0009953 [dorsal/ventral pattern formation] evidence: ISS
            GeneID:4010 -> Biological process: GO:0021587 [cerebellum morphogenesis] evidence: IEA
            GeneID:4010 -> Biological process: GO:0021954 [central nervous system neuron development] evidence: IEA
            GeneID:4010 -> Biological process: GO:0030182 [neuron differentiation] evidence: ISS
            GeneID:4010 -> Biological process: GO:0030199 [collagen fibril organization] evidence: IEA
            GeneID:4010 -> Biological process: GO:0030901 [midbrain development] evidence: IEA
            GeneID:4010 -> Biological process: GO:0035108 [limb morphogenesis] evidence: IEA
            GeneID:4010 -> Biological process: GO:0035265 [organ growth] evidence: IEA
            GeneID:4010 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IEA
            GeneID:4010 -> Biological process: GO:0071542 [dopaminergic neuron differentiation] evidence: IEA
            GeneID:4010 -> Cellular component: GO:0005634 [nucleus] evidence: IDA