Home |
Help |
Advanced search
2024-04-19 07:43:12, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_002306 1017 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens lectin, galactoside-binding, soluble, 3 (LGALS3),
transcript variant 1, mRNA.
ACCESSION NM_002306
VERSION NM_002306.3 GI:294345473
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1017)
AUTHORS Woodward,A.M., Mauris,J. and Argueso,P.
TITLE Binding of transmembrane mucins to galectin-3 limits herpesvirus 1
infection of human corneal keratinocytes
JOURNAL J. Virol. 87 (10), 5841-5847 (2013)
PUBMED 23487460
REMARK GeneRIF: Together, these results indicate that human herpesvirus 1
exploits galectin-3 to enhance virus attachment to host cells and
support a protective role for transmembrane by masking viral entry
mediators on the epithelial glycocalyx.
REFERENCE 2 (bases 1 to 1017)
AUTHORS Funasaka,T., Balan,V., Raz,A. and Wong,R.W.
TITLE Nucleoporin Nup98 mediates galectin-3 nuclear-cytoplasmic
trafficking
JOURNAL Biochem. Biophys. Res. Commun. 434 (1), 155-161 (2013)
PUBMED 23541576
REMARK GeneRIF: Nup98 RNA interference significantly suppresses downstream
mRNA expression in the ss-catenin pathway, while nuclear galectin-3
binds to ss-catenin to inhibit transcriptional activity.
REFERENCE 3 (bases 1 to 1017)
AUTHORS Cheng,C.L., Hou,H.A., Lee,M.C., Liu,C.Y., Jhuang,J.Y., Lai,Y.J.,
Lin,C.W., Chen,H.Y., Liu,F.T., Chou,W.C., Chen,C.Y., Tang,J.L.,
Yao,M., Huang,S.Y., Ko,B.S., Wu,S.J., Tsay,W. and Tien,H.F.
TITLE Higher bone marrow LGALS3 expression is an independent unfavorable
prognostic factor for overall survival in patients with acute
myeloid leukemia
JOURNAL Blood 121 (16), 3172-3180 (2013)
PUBMED 23449638
REMARK GeneRIF: Higher bone marrow LGALS3 expression is an independent
poor prognostic factor for overall survival and may serve as a
potential therapeutic target.
REFERENCE 4 (bases 1 to 1017)
AUTHORS Guha,P., Kaptan,E., Bandyopadhyaya,G., Kaczanowska,S., Davila,E.,
Thompson,K., Martin,S.S., Kalvakolanu,D.V., Vasta,G.R. and Ahmed,H.
TITLE Cod glycopeptide with picomolar affinity to galectin-3 suppresses
T-cell apoptosis and prostate cancer metastasis
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 110 (13), 5052-5057 (2013)
PUBMED 23479624
REMARK GeneRIF: Cod glycopeptide with picomolar affinity to galectin-3
suppresses T-cell apoptosis and prostate cancer metastasis.
REFERENCE 5 (bases 1 to 1017)
AUTHORS Raimond,J., Zimonjic,D.B., Mignon,C., Mattei,M., Popescu,N.C.,
Monsigny,M. and Legrand,A.
TITLE Mapping of the galectin-3 gene (LGALS3) to human chromosome 14 at
region 14q21-22
JOURNAL Mamm. Genome 8 (9), 706-707 (1997)
PUBMED 9271684
REFERENCE 6 (bases 1 to 1017)
AUTHORS Rosenberg,I., Cherayil,B.J., Isselbacher,K.J. and Pillai,S.
TITLE Mac-2-binding glycoproteins. Putative ligands for a cytosolic
beta-galactoside lectin
JOURNAL J. Biol. Chem. 266 (28), 18731-18736 (1991)
PUBMED 1917996
REFERENCE 7 (bases 1 to 1017)
AUTHORS Raz,A., Carmi,P., Raz,T., Hogan,V., Mohamed,A. and Wolman,S.R.
TITLE Molecular cloning and chromosomal mapping of a human
galactoside-binding protein
JOURNAL Cancer Res. 51 (8), 2173-2178 (1991)
PUBMED 2009535
REFERENCE 8 (bases 1 to 1017)
AUTHORS Oda,Y., Leffler,H., Sakakura,Y., Kasai,K. and Barondes,S.H.
TITLE Human breast carcinoma cDNA encoding a galactoside-binding lectin
homologous to mouse Mac-2 antigen
JOURNAL Gene 99 (2), 279-283 (1991)
PUBMED 2022338
REFERENCE 9 (bases 1 to 1017)
AUTHORS Gitt,M.A. and Barondes,S.H.
TITLE Genomic sequence and organization of two members of a human lectin
gene family
JOURNAL Biochemistry 30 (1), 82-89 (1991)
PUBMED 1988031
REFERENCE 10 (bases 1 to 1017)
AUTHORS Cherayil,B.J., Chaitovitz,S., Wong,C. and Pillai,S.
TITLE Molecular cloning of a human macrophage lectin specific for
galactose
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87 (18), 7324-7328 (1990)
PUBMED 2402511
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from CD518618.1, AB006780.1 and
BU681070.1.
This sequence is a reference standard in the RefSeqGene project.
On Apr 8, 2010 this sequence version replaced gi:115430222.
Summary: This gene encodes a member of the galectin family of
carbohydrate binding proteins. Members of this protein family have
an affinity for beta-galactosides. The encoded protein is
characterized by an N-terminal proline-rich tandem repeat domain
and a single C-terminal carbohydrate recognition domain. This
protein can self-associate through the N-terminal domain allowing
it to bind to multivalent saccharide ligands. This protein
localizes to the extracellular matrix, the cytoplasm and the
nucleus. This protein plays a role in numerous cellular functions
including apoptosis, innate immunity, cell adhesion and T-cell
regulation. Alternate splicing results in multiple transcript
variants.[provided by RefSeq, Apr 2010].
Transcript Variant: This variant (1) encodes the longer isoform
(1).
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: CD518618.1, BM471153.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025083 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: full length.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-35 CD518618.1 1-35
36-978 AB006780.1 1-943
979-1017 BU681070.1 1-39 c
FEATURES Location/Qualifiers
source 1..1017
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="14"
/map="14q22.3"
gene 1..1017
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/note="lectin, galactoside-binding, soluble, 3"
/db_xref="GeneID:3958"
/db_xref="HGNC:6563"
/db_xref="MIM:153619"
exon 1..84
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/inference="alignment:Splign:1.39.8"
misc_feature 8..10
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/note="upstream in-frame stop codon"
variation 37
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:368553467"
variation 42
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371374433"
exon 85..106
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/inference="alignment:Splign:1.39.8"
CDS 89..841
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/note="isoform 1 is encoded by transcript variant 1;
galactose-specific lectin 3; MAC-2 antigen; IgE-binding
protein; carbohydrate-binding protein 35; laminin-binding
protein; lectin L-29; 35 kDa lectin"
/codon_start=1
/product="galectin-3 isoform 1"
/protein_id="NP_002297.2"
/db_xref="GI:115430223"
/db_xref="CCDS:CCDS41956.1"
/db_xref="GeneID:3958"
/db_xref="HGNC:6563"
/db_xref="MIM:153619"
/translation="
MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
"
misc_feature 104..106
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(P17931.5); phosphorylation site"
misc_feature 104..106
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:00277"
misc_feature 104..106
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:00279"
misc_feature 104..106
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:02739"
misc_feature 122..124
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(P17931.5); phosphorylation site"
misc_feature 122..124
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:00277"
misc_feature 122..124
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:00279"
misc_feature 122..124
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/experiment="experimental evidence, no additional details
recorded"
/note="phosphorylation site"
/db_xref="HPRD:02739"
misc_feature 194..415
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P17931.5);
Region: 8 X 9 AA tandem repeats of Y-P-G-X(3)-P-G-A"
misc_feature 437..820
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/note="Galectin/galactose-binding lectin. This domain
exclusively binds beta-galactosides, such as lactose, and
does not require metal ions for activity. GLECT domains
occur as homodimers or tandemly repeated domains. They are
developmentally regulated and may...; Region: GLECT;
cd00070"
/db_xref="CDD:28952"
misc_feature order(440..454,809..820)
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:28952"
misc_feature 440..454
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/note="dimerization swap strand; other site"
/db_xref="CDD:28952"
misc_feature order(467..475,482..484,491..493,695..703,716..718,
722..724,731..733)
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/note="putative alternate dimerization interface
[polypeptide binding]; other site"
/db_xref="CDD:28952"
misc_feature order(560..562,566..568,572..574,602..604,608..610,
629..631,638..640,644..646)
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/note="sugar binding pocket [chemical binding]; other
site"
/db_xref="CDD:28952"
misc_feature 629..649
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (P17931.5);
Region: Beta-galactoside binding (By similarity)"
misc_feature 764..811
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (P17931.5);
Region: Nuclear export signal (By similarity)"
variation 106
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="g"
/db_xref="dbSNP:78001930"
exon 107..430
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/inference="alignment:Splign:1.39.8"
variation 112
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:188973411"
variation 117
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:202159462"
variation 118
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="g"
/db_xref="dbSNP:11538648"
variation 160
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:181337247"
variation 161
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="g"
/db_xref="dbSNP:367771588"
variation 200
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="g"
/db_xref="dbSNP:199980622"
variation 225
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="g"
/db_xref="dbSNP:200440596"
variation 226
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:375563484"
variation 227
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201423229"
variation 246
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="c"
/db_xref="dbSNP:201924703"
variation 248
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:11538647"
variation 272
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374075223"
variation 278
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="g"
/db_xref="dbSNP:375132388"
variation 279
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="c"
/db_xref="dbSNP:4644"
variation 288
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372168966"
variation 301
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:61735588"
variation 342
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="g"
/replace="t"
/db_xref="dbSNP:201462121"
variation 368
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="g"
/db_xref="dbSNP:148184206"
variation 380
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="c"
/db_xref="dbSNP:4652"
variation 382
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:78964872"
variation 390
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="c"
/db_xref="dbSNP:200922957"
variation 397
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372459819"
variation 400
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="g"
/replace="t"
/db_xref="dbSNP:377311837"
variation 428
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="g"
/db_xref="dbSNP:369880363"
exon 431..519
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/inference="alignment:Splign:1.39.8"
variation 474
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201398647"
variation 482
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="g"
/db_xref="dbSNP:370418608"
variation 519
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374133862"
exon 520..685
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/inference="alignment:Splign:1.39.8"
variation 526
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371871619"
variation 536
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="g"
/db_xref="dbSNP:199729394"
STS 544..689
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/standard_name="RH69146"
/db_xref="UniSTS:42649"
variation 547
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:184778469"
variation 550
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:145296140"
variation 572
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:376506811"
variation 573
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201865041"
variation 586
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201301078"
variation 589
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:137885280"
variation 599
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="g"
/db_xref="dbSNP:189412756"
variation 636
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="g"
/db_xref="dbSNP:10148371"
variation 651
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200686001"
variation 660
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373019488"
exon 686..1000
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/inference="alignment:Splign:1.39.8"
variation 686
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201096256"
variation 691
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="t"
/db_xref="dbSNP:11125"
STS 705..855
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/standard_name="WI-15390"
/db_xref="UniSTS:38423"
variation 746
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:11001"
variation 772
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="c"
/db_xref="dbSNP:374550386"
variation 798
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:1042869"
variation 807
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:150161752"
variation 827
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:138668217"
variation 843
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:1042896"
variation 857
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="t"
/db_xref="dbSNP:61975414"
variation 859
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="t"
/db_xref="dbSNP:74959172"
variation 860
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace=""
/replace="a"
/db_xref="dbSNP:71659941"
variation 862..863
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace=""
/replace="a"
/replace="aa"
/db_xref="dbSNP:71736436"
variation 876
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:1042906"
variation 891
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371349669"
variation 908
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="c"
/db_xref="dbSNP:1042918"
variation 920
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="a"
/replace="c"
/db_xref="dbSNP:369980295"
variation 938
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace="c"
/replace="t"
/db_xref="dbSNP:182580267"
polyA_signal 963..968
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
variation 993..994
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
/replace=""
/replace="at"
/db_xref="dbSNP:149894805"
polyA_site 1000
/gene="LGALS3"
/gene_synonym="CBP35; GAL3; GALBP; GALIG; L31; LGALS2;
MAC2"
ORIGIN
gagtatttgaggctcggagccaccgccccgccggcgcccgcagcacctcctcgccagcagccgtccggagccagccaacgagcggaaaatggcagacaatttttcgctccatgatgcgttatctgggtctggaaacccaaaccctcaaggatggcctggcgcatgggggaaccagcctgctggggcagggggctacccaggggcttcctatcctggggcctaccccgggcaggcacccccaggggcttatcctggacaggcacctccaggcgcctaccctggagcacctggagcttatcccggagcacctgcacctggagtctacccagggccacccagcggccctggggcctacccatcttctggacagccaagtgccaccggagcctaccctgccactggcccctatggcgcccctgctgggccactgattgtgccttataacctgcctttgcctgggggagtggtgcctcgcatgctgataacaattctgggcacggtgaagcccaatgcaaacagaattgctttagatttccaaagagggaatgatgttgccttccactttaacccacgcttcaatgagaacaacaggagagtcattgtttgcaatacaaagctggataataactggggaagggaagaaagacagtcggttttcccatttgaaagtgggaaaccattcaaaatacaagtactggttgaacctgaccacttcaaggttgcagtgaatgatgctcacttgttgcagtacaatcatcgggttaaaaaactcaatgaaatcagcaaactgggaatttctggtgacatagacctcaccagtgcttcatataccatgatataatctgaaaggggcagattaaaaaaaaaaaaagaatctaaaccttacatgtgtaaaggtttcatgttcactgtgagtgaaaatttttacattcatcaatatccctcttgtaagtcatctacttaataaatattacagtgaattacctgtctcaatatgtcaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:3958 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:3958 -> Molecular function: GO:0019863 [IgE binding] evidence: IEA
GeneID:3958 -> Molecular function: GO:0030246 [carbohydrate binding] evidence: IEA
GeneID:3958 -> Biological process: GO:0001501 [skeletal system development] evidence: IEA
GeneID:3958 -> Biological process: GO:0006397 [mRNA processing] evidence: IEA
GeneID:3958 -> Biological process: GO:0008380 [RNA splicing] evidence: IEA
GeneID:3958 -> Biological process: GO:0030154 [cell differentiation] evidence: IEA
GeneID:3958 -> Biological process: GO:0030198 [extracellular matrix organization] evidence: IEA
GeneID:3958 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
GeneID:3958 -> Cellular component: GO:0005578 [proteinaceous extracellular matrix] evidence: IEA
GeneID:3958 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:3958 -> Cellular component: GO:0005681 [spliceosomal complex] evidence: IEA
GeneID:3958 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:3958 -> Cellular component: GO:0005743 [mitochondrial inner membrane] evidence: IDA
GeneID:3958 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS
GeneID:3958 -> Cellular component: GO:0031012 [extracellular matrix] evidence: IDA
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.