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2024-04-24 03:38:58, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_002006 6774 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens fibroblast growth factor 2 (basic) (FGF2), mRNA.
ACCESSION NM_002006
VERSION NM_002006.4 GI:153285460
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6774)
AUTHORS Zhou,B., Ma,R., Si,W., Li,S., Xu,Y., Tu,X. and Wang,Q.
TITLE MicroRNA-503 targets FGF2 and VEGFA and inhibits tumor angiogenesis
and growth
JOURNAL Cancer Lett. 333 (2), 159-169 (2013)
PUBMED 23352645
REMARK GeneRIF: a novel mechanism for hypoxia-induced FGF2 and VEGFA
through HIF1alpha-mediated inhibition of miR-503
REFERENCE 2 (bases 1 to 6774)
AUTHORS Li,B., Pi,Z., Liu,L., Zhang,B., Huang,X., Hu,P., Chevet,E., Yi,P.
and Liu,J.
TITLE FGF-2 prevents cancer cells from ER stress-mediated apoptosis via
enhancing proteasome-mediated Nck degradation
JOURNAL Biochem. J. 452 (1), 139-145 (2013)
PUBMED 23448571
REMARK GeneRIF: Nck plays a pivotal role in integrating FGF-2 and
endoplasmic reticulum (ER) stress signals to counteract the ER
stress deleterious effect on cancer cell survival.
REFERENCE 3 (bases 1 to 6774)
AUTHORS Cuevas,R., Korzeniewski,N., Tolstov,Y., Hohenfellner,M. and
Duensing,S.
TITLE FGF-2 disrupts mitotic stability in prostate cancer through the
intracellular trafficking protein CEP57
JOURNAL Cancer Res. 73 (4), 1400-1410 (2013)
PUBMED 23243019
REMARK GeneRIF: Data suggest for therapeutic targeting of the
FGF-2/FGFR1/CEP57 axis in prostate cancer.
REFERENCE 4 (bases 1 to 6774)
AUTHORS Platonova,N., Miquel,G., Regenfuss,B., Taouji,S., Cursiefen,C.,
Chevet,E. and Bikfalvi,A.
TITLE Evidence for the interaction of fibroblast growth factor-2 with the
lymphatic endothelial cell marker LYVE-1
JOURNAL Blood 121 (7), 1229-1237 (2013)
PUBMED 23264596
REMARK GeneRIF: FGF2 binds to LYVE-1 with a higher affinity than any other
known LYVE-1-binding molecules, such as hyaluronan or PDGF-BB.
Glycosylation of LYVE-1 is important for FGF2 binding.
REFERENCE 5 (bases 1 to 6774)
AUTHORS Arnaud,E., Touriol,C., Boutonnet,C., Gensac,M.C., Vagner,S.,
Prats,H. and Prats,A.C.
TITLE A new 34-kilodalton isoform of human fibroblast growth factor 2 is
cap dependently synthesized by using a non-AUG start codon and
behaves as a survival factor
JOURNAL Mol. Cell. Biol. 19 (1), 505-514 (1999)
PUBMED 9858574
REMARK GeneRIF: A new FGF2 isoform results from the use of a non-AUG (CUG)
translation initiation codon.
REFERENCE 6 (bases 1 to 6774)
AUTHORS Watson,R., Anthony,F., Pickett,M., Lambden,P., Masson,G.M. and
Thomas,E.J.
TITLE Reverse transcription with nested polymerase chain reaction shows
expression of basic fibroblast growth factor transcripts in human
granulosa and cumulus cells from in vitro fertilisation patients
JOURNAL Biochem. Biophys. Res. Commun. 187 (3), 1227-1231 (1992)
PUBMED 1417798
REFERENCE 7 (bases 1 to 6774)
AUTHORS Eriksson,A.E., Cousens,L.S., Weaver,L.H. and Matthews,B.W.
TITLE Three-dimensional structure of human basic fibroblast growth factor
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 88 (8), 3441-3445 (1991)
PUBMED 1707542
REFERENCE 8 (bases 1 to 6774)
AUTHORS Zhu,X., Komiya,H., Chirino,A., Faham,S., Fox,G.M., Arakawa,T.,
Hsu,B.T. and Rees,D.C.
TITLE Three-dimensional structures of acidic and basic fibroblast growth
factors
JOURNAL Science 251 (4989), 90-93 (1991)
PUBMED 1702556
REFERENCE 9 (bases 1 to 6774)
AUTHORS Dionne,C.A., Crumley,G., Bellot,F., Kaplow,J.M., Searfoss,G.,
Ruta,M., Burgess,W.H., Jaye,M. and Schlessinger,J.
TITLE Cloning and expression of two distinct high-affinity receptors
cross-reacting with acidic and basic fibroblast growth factors
JOURNAL EMBO J. 9 (9), 2685-2692 (1990)
PUBMED 1697263
REFERENCE 10 (bases 1 to 6774)
AUTHORS Prats,H., Kaghad,M., Prats,A.C., Klagsbrun,M., Lelias,J.M.,
Liauzun,P., Chalon,P., Tauber,J.P., Amalric,F., Smith,J.A. et al.
TITLE High molecular mass forms of basic fibroblast growth factor are
initiated by alternative CUG codons
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86 (6), 1836-1840 (1989)
PUBMED 2538817
REMARK GeneRIF: Alternate protein isoforms arise through the use of AUG
and non-AUG (CUG) translation initiation codons.
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from J04513.1, AC021205.6, M27968.1,
BU501243.1, BP292299.1, CN315083.1 and AA256481.1.
This sequence is a reference standard in the RefSeqGene project.
On Jul 24, 2007 this sequence version replaced gi:41352694.
Summary: The protein encoded by this gene is a member of the
fibroblast growth factor (FGF) family. FGF family members bind
heparin and possess broad mitogenic and angiogenic activities. This
protein has been implicated in diverse biological processes, such
as limb and nervous system development, wound healing, and tumor
growth. The mRNA for this gene contains multiple polyadenylation
sites, and is alternatively translated from non-AUG (CUG) and AUG
initiation codons, resulting in five different isoforms with
distinct properties. The CUG-initiated isoforms are localized in
the nucleus and are responsible for the intracrine effect, whereas,
the AUG-initiated form is mostly cytosolic and is responsible for
the paracrine and autocrine effects of this FGF. [provided by
RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: J04513.1, M27968.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
##RefSeq-Attributes-START##
non-AUG initiation codon :: PMID: 2538817
##RefSeq-Attributes-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-79 J04513.1 1-79
80-142 AC021205.6 16703-16765
143-2746 J04513.1 142-2745
2747-2870 M27968.1 2621-2744
2871-3405 J04513.1 2870-3404
3406-3827 M27968.1 3280-3701
3828-4626 BU501243.1 28-826
4627-5067 BP292299.1 143-583
5068-5681 J04513.1 5065-5678
5682-6161 CN315083.1 106-585
6162-6760 J04513.1 6159-6757
6761-6774 AA256481.1 1-14 c
FEATURES Location/Qualifiers
source 1..6774
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="4"
/map="4q26"
gene 1..6774
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/note="fibroblast growth factor 2 (basic)"
/db_xref="GeneID:2247"
/db_xref="HGNC:3676"
/db_xref="MIM:134920"
exon 1..645
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/inference="alignment:Splign:1.39.8"
misc_feature 24..26
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/note="upstream in-frame stop codon"
variation 44
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:112806407"
CDS 69..935
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/note="34-kDa isoform;~non-AUG (CUG) translation
initiation codon; prostatropin; heparin-binding growth
factor 2; basic fibroblast growth factor bFGF"
/codon_start=1
/product="fibroblast growth factor 2"
/protein_id="NP_001997.5"
/db_xref="GI:153285461"
/db_xref="CCDS:CCDS34059.1"
/db_xref="GeneID:2247"
/db_xref="HGNC:3676"
/db_xref="MIM:134920"
/translation="
MVGVGGGDVEDVTPRPGGCQISGRGARGCNGIPGAAAWEAALPRRRPRRHPSVNPRSRAAGSPRTRGRRTEERPSGSRLGDRGRGRALPGGRLGGRGRGRAPERVGGRGRGRGTAAPRAAPAARGSRPGPAGTMAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
"
misc_feature 303..305
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/note="Region: 24-kDa isoform; alternative non-AUG (CUG)
translation initiation site"
misc_feature 330..332
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/note="Region: 22.5-kDa isoform; alternative non-AUG (CUG)
translation initiation site"
misc_feature 345..347
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/note="Region: 22-kDa isoform; alternative non-AUG (CUG)
translation initiation site"
misc_feature 468..470
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/note="Region: 18-kDa isoform; alternative AUG translation
initiation site"
misc_feature 555..923
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/note="Acidic and basic fibroblast growth factor family;
FGFs are mitogens, which stimulate growth or
differentiation of cells of mesodermal or neuroectodermal
origin. The family plays essential roles in patterning and
differentiation during vertebrate...; Region: FGF;
cd00058"
/db_xref="CDD:28940"
misc_feature order(555..557,564..566,660..662,666..668,672..674,
756..758,780..782,789..806,810..812,906..908,912..914,
918..920)
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/note="receptor interaction site; other site"
/db_xref="CDD:28940"
misc_feature 603..611
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (P09038.3);
Region: Cell attachment site, atypical (Potential)"
misc_feature 711..713
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphotyrosine, by TEC; propagated from
UniProtKB/Swiss-Prot (P09038.3); phosphorylation site"
misc_feature 729..737
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (P09038.3);
Region: Cell attachment site, atypical (Potential)"
misc_feature 849..899
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (P09038.3);
Region: Heparin-binding (By similarity)"
misc_feature order(849..854,867..869,879..881,897..899)
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/note="heparin binding site (glycine box) [chemical
binding]; other site"
/db_xref="CDD:28940"
variation 80
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:308400"
variation 81
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:75664870"
variation 82
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201837669"
variation 85
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201172719"
STS 87..1415
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/db_xref="UniSTS:481492"
variation 116
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:375703544"
variation 189
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="g"
/replace="t"
/db_xref="dbSNP:369126645"
variation 215
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:45626542"
variation 224
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:1449683"
STS 275..966
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/db_xref="UniSTS:482299"
variation 529
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377033294"
variation 533
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:113672587"
variation 566
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:113537066"
variation 602
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:374332071"
variation 611
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/db_xref="dbSNP:183060480"
exon 646..749
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/inference="alignment:Splign:1.39.8"
variation 650
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="g"
/replace="t"
/db_xref="dbSNP:148587537"
STS 652..934
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/standard_name="Fgf2"
/db_xref="UniSTS:464707"
variation 689
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:111739298"
variation 695
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:199515030"
variation 696
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:113754132"
variation 735
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/db_xref="dbSNP:371914186"
exon 750..6774
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/inference="alignment:Splign:1.39.8"
variation 760
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:151141410"
variation 761
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201116035"
variation 786
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:140131552"
variation 824
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:145325930"
variation 941
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:374325832"
variation 942
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:111250029"
STS 944..1160
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/standard_name="SHGC-31504"
/db_xref="UniSTS:48341"
variation 1019
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:112067954"
variation 1030
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:186312788"
variation 1039
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:3804156"
variation 1103
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/db_xref="dbSNP:45627736"
variation 1330
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:377651203"
variation 1331
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:200167049"
variation 1372
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/db_xref="dbSNP:146460670"
variation 1374
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:371113958"
variation 1408
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:372832872"
variation 1473
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377283871"
variation 1479
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:369858295"
variation 1508
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:148123353"
variation 1527
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:140973799"
variation 1534
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:375542320"
variation 1548
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:45606640"
variation 1554
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:138619142"
variation 1619
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201373471"
variation 1635
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:142756927"
variation 1661
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:369473521"
variation 1669
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:199533328"
variation 1689
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="g"
/replace="t"
/db_xref="dbSNP:372728120"
variation 1692
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:1048201"
variation 1705
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201458145"
variation 1706
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:113836715"
variation 1729
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201412128"
variation 1733
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/db_xref="dbSNP:374780215"
variation 1743
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:11541431"
variation 1754
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/db_xref="dbSNP:200650453"
variation 1755
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:112477231"
variation 1768
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:199833283"
variation 1769
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="g"
/replace="t"
/db_xref="dbSNP:45625032"
variation 1786
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:189490769"
variation 1885
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:112392401"
variation 1985
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace=""
/replace="t"
/db_xref="dbSNP:11340920"
variation 2155
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:181591190"
variation 2284
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:3804158"
variation 2304
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:186943746"
variation 2366
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:191364640"
variation 2370
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371852060"
variation 2400
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:375179461"
variation 2402
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:45604541"
variation 2452
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="g"
/replace="t"
/db_xref="dbSNP:75598432"
variation 2465
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:41501547"
variation 2499
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:183122876"
variation 2519
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="g"
/replace="t"
/db_xref="dbSNP:112645817"
variation 2686
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/db_xref="dbSNP:45552632"
variation 2736
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:45520244"
variation 2746
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:2893026"
variation 2747
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:41348645"
variation 2852
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:45492897"
variation 2882
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/db_xref="dbSNP:45626132"
STS 2913..3034
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/standard_name="D15S1390"
/db_xref="UniSTS:474340"
STS 2914..3117
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/standard_name="SHGC-67307"
/db_xref="UniSTS:89991"
variation 3019
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:45446702"
variation 3048
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:111829757"
variation 3158..3159
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace=""
/replace="a"
/db_xref="dbSNP:45571542"
variation 3204
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="t"
/db_xref="dbSNP:113612713"
variation 3240
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="t"
/db_xref="dbSNP:78432795"
variation 3249
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:45440094"
variation 3261
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="t"
/db_xref="dbSNP:111907203"
polyA_signal 3316..3321
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
polyA_site 3333
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
variation 3406
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:45504296"
variation 3480
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:186613784"
variation 3508
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:2168915"
variation 3675
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:6853268"
variation 3701
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:11540088"
variation 3737
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:190613209"
variation 3884
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="t"
/db_xref="dbSNP:182205477"
variation 3956
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:45441398"
variation 3972
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="g"
/replace="t"
/db_xref="dbSNP:113615485"
polyA_signal 3984..3989
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
polyA_site 4005
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
variation 4022
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:77571189"
variation 4077
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/db_xref="dbSNP:187737646"
variation 4091
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="g"
/replace="t"
/db_xref="dbSNP:6854081"
variation 4098
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:377638739"
variation 4117
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:371110764"
variation 4177
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:45495095"
variation 4277..4279
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace=""
/replace="ttc"
/db_xref="dbSNP:45546532"
variation 4295
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:112480130"
variation 4373
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:139580294"
variation 4391
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:149304849"
variation 4398
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:373292533"
variation 4411
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144487286"
variation 4458
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="g"
/replace="t"
/db_xref="dbSNP:111822781"
variation 4559
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:3804159"
variation 4606
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:3827582"
variation 4637
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:45507392"
variation 4638
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:62323463"
variation 4687
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:112821043"
variation 4716
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:192660532"
variation 4721
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace=""
/replace="t"
/db_xref="dbSNP:3840102"
variation 4723
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="g"
/replace="t"
/db_xref="dbSNP:200464258"
variation 4733
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="t"
/db_xref="dbSNP:62855160"
variation 4776
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="g"
/replace="t"
/db_xref="dbSNP:41512344"
variation 4790
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:182831170"
variation 4866
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:41481046"
variation 4912
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:7655413"
variation 4974
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:367996400"
variation 4976
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/db_xref="dbSNP:113212565"
variation 5058
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:45575341"
variation 5234
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:45555832"
variation 5259
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="g"
/replace="t"
/db_xref="dbSNP:112306097"
variation 5270
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:45598131"
variation 5345
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:45561135"
variation 5348
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:188483729"
variation 5371
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:111912304"
variation 5428
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:76656561"
variation 5458
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:3747676"
variation 5469
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:7683093"
variation 5514
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:373076210"
variation 5524
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/db_xref="dbSNP:45598031"
variation 5631
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:45594531"
variation 5655
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="t"
/db_xref="dbSNP:1476215"
variation 5656
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:115581650"
variation 5682
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="t"
/db_xref="dbSNP:1476216"
variation 5684
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/db_xref="dbSNP:193177947"
variation 5895
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/db_xref="dbSNP:1476217"
variation 5940
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:41278093"
variation 6017
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="t"
/db_xref="dbSNP:45628734"
variation 6047
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:184614458"
variation 6080
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:112096878"
variation 6095
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:189884686"
variation 6112
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:369016432"
variation 6117
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:201425662"
variation 6123
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:201003321"
variation 6176
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:201825800"
variation 6206
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:147264289"
variation 6228
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/db_xref="dbSNP:112772657"
variation 6244
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:113287409"
variation 6256
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:200889371"
variation 6270..6271
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace=""
/replace="at"
/db_xref="dbSNP:61524225"
STS 6291..6518
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/standard_name="SHGC-59517"
/db_xref="UniSTS:24667"
variation 6397
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="g"
/db_xref="dbSNP:45593942"
variation 6424
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="c"
/db_xref="dbSNP:111619148"
variation 6443
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="c"
/replace="t"
/db_xref="dbSNP:191242224"
STS 6483..6581
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/standard_name="SHGC-59784"
/db_xref="UniSTS:12969"
variation 6561
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:111907732"
variation 6585
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="t"
/db_xref="dbSNP:183971761"
polyA_signal 6740..6745
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
variation 6754
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
/replace="a"
/replace="g"
/db_xref="dbSNP:144978673"
polyA_site 6763
/gene="FGF2"
/gene_synonym="BFGF; FGF-2; FGFB; HBGF-2"
ORIGIN
cggccccagaaaacccgagcgagtagggggcggcgcgcaggagggaggagaactgggggcgcgggaggctggtgggtgtggggggtggagatgtagaagatgtgacgccgcggcccggcgggtgccagattagcggacgcggtgcccgcggttgcaacgggatcccgggcgctgcagcttgggaggcggctctccccaggcggcgtccgcggagacacccatccgtgaaccccaggtcccgggccgccggctcgccgcgcaccaggggccggcggacagaagagcggccgagcggctcgaggctgggggaccgcgggcgcggccgcgcgctgccgggcgggaggctggggggccggggccggggccgtgccccggagcgggtcggaggccggggccggggccgggggacggcggctccccgcgcggctccagcggctcggggatcccggccgggccccgcagggaccatggcagccgggagcatcaccacgctgcccgccttgcccgaggatggcggcagcggcgccttcccgcccggccacttcaaggaccccaagcggctgtactgcaaaaacgggggcttcttcctgcgcatccaccccgacggccgagttgacggggtccgggagaagagcgaccctcacatcaagctacaacttcaagcagaagagagaggagttgtgtctatcaaaggagtgtgtgctaaccgttacctggctatgaaggaagatggaagattactggcttctaaatgtgttacggatgagtgtttcttttttgaacgattggaatctaataactacaatacttaccggtcaaggaaatacaccagttggtatgtggcactgaaacgaactgggcagtataaacttggatccaaaacaggacctgggcagaaagctatactttttcttccaatgtctgctaagagctgattttaatggccacatctaatctcatttcacatgaaagaagaagtatattttagaaatttgttaatgagagtaaaagaaaataaatgtgtatagctcagtttggataattggtcaaacaattttttatccagtagtaaaatatgtaaccattgtcccagtaaagaaaaataacaaaagttgtaaaatgtatattctcccttttatattgcatctgctgttacccagtgaagcttacctagagcaatgatctttttcacgcatttgctttattcgaaaagaggcttttaaaatgtgcatgtttagaaacaaaatttcttcatggaaatcatatacattagaaaatcacagtcagatgtttaatcaatccaaaatgtccactatttcttatgtcattcgttagtctacatgtttctaaacatataaatgtgaatttaatcaattcctttcatagttttataattctctggcagttccttatgatagagtttataaaacagtcctgtgtaaactgctggaagttcttccacagtcaggtcaattttgtcaaacccttctctgtacccatacagcagcagcctagcaactctgctggtgatgggagttgtattttcagtcttcgccaggtcattgagatccatccactcacatcttaagcattcttcctggcaaaaatttatggtgaatgaatatggctttaggcggcagatgatatacatatctgacttcccaaaagctccaggatttgtgtgctgttgccgaatactcaggacggacctgaattctgattttataccagtctcttcaaaaacttctcgaaccgctgtgtctcctacgtaaaaaaagagatgtacaaatcaataataattacacttttagaaactgtatcatcaaagattttcagttaaagtagcattatgtaaaggctcaaaacattaccctaacaaagtaaagttttcaatacaaattctttgccttgtggatatcaagaaatcccaaaatattttcttaccactgtaaattcaagaagcttttgaaatgctgaatatttctttggctgctacttggaggcttatctacctgtacatttttggggtcagctctttttaacttcttgctgctctttttcccaaaaggtaaaaatatagattgaaaagttaaaacattttgcatggctgcagttcctttgtttcttgagataagattccaaagaacttagattcatttcttcaacaccgaaatgctggaggtgtttgatcagttttcaagaaacttggaatataaataattttataattcaacaaaggttttcacattttataaggttgatttttcaattaaatgcaaatttgtgtggcaggatttttattgccattaacatatttttgtggctgctttttctacacatccagatggtccctctaactgggctttctctaattttgtgatgttctgtcattgtctcccaaagtatttaggagaagccctttaaaaagctgccttcctctaccactttgctggaaagcttcacaattgtcacagacaaagatttttgttccaatactcgttttgcctctatttttcttgtttgtcaaatagtaaatgatatttgcccttgcagtaattctactggtgaaaaacatgcaaagaagaggaagtcacagaaacatgtctcaattcccatgtgctgtgactgtagactgtcttaccatagactgtcttacccatcccctggatatgctcttgttttttccctctaatagctatggaaagatgcatagaaagagtataatgttttaaaacataaggcattcgtctgccatttttcaattacatgctgacttcccttacaattgagatttgcccataggttaaacatggttagaaacaactgaaagcataaaagaaaaatctaggccgggtgcagtggctcatgcctatattccctgcactttgggaggccaaagcaggaggatcgcttgagcccaggagttcaagaccaacctggtgaaaccccgtctctacaaaaaaacacaaaaaatagccaggcatggtggcgtgtacatgtggtctcagatacttgggaggctgaggtgggagggttgatcacttgaggctgagaggtcaaggttgcagtgagccataatcgtgccactgcagtccagcctaggcaacagagtgagactttgtctcaaaaaaagagaaattttccttaataagaaaagtaatttttactctgatgtgcaatacatttgttattaaatttattatttaagatggtagcactagtcttaaattgtataaaatatcccctaacatgtttaaatgtccatttttattcattatgctttgaaaaataattatggggaaatacatgtttgttattaaatttattattaaagatagtagcactagtcttaaatttgatataacatctcctaacttgtttaaatgtccatttttattctttatgtttgaaaataaattatggggatcctatttagctcttagtaccactaatcaaaagttcggcatgtagctcatgatctatgctgtttctatgtcgtggaagcaccggatgggggtagtgagcaaatctgccctgctcagcagtcaccatagcagctgactgaaaatcagcactgcctgagtagttttgatcagtttaacttgaatcactaactgactgaaaattgaatgggcaaataagtgcttttgtctccagagtatgcgggagacccttccacctcaagatggatatttcttccccaaggatttcaagatgaattgaaatttttaatcaagatagtgtgctttattctgttgtattttttattattttaatatactgtaagccaaactgaaataacatttgctgttttataggtttgaagaacataggaaaaactaagaggttttgtttttatttttgctgatgaagagatatgtttaaatatgttgtattgttttgtttagttacaggacaataatgaaatggagtttatatttgttatttctattttgttatatttaataatagaattagattgaaataaaatataatgggaaataatctgcagaatgtgggttttcctggtgtttccctctgactctagtgcactgatgatctctgataaggctcagctgctttatagttctctggctaatgcagcagatactcttcctgccagtggtaatacgattttttaagaaggcagtttgtcaattttaatcttgtggatacctttatactcttagggtattattttatacaaaagccttgaggattgcattctattttctatatgaccctcttgatatttaaaaaacactatggataacaattcttcatttacctagtattatgaaagaatgaaggagttcaaacaaatgtgtttcccagttaactagggtttactgtttgagccaatataaatgtttaactgtttgtgatggcagtattcctaaagtacattgcatgttttcctaaatacagagtttaaataatttcagtaattcttagatgattcagcttcatcattaagaatatcttttgttttatgttgagttagaaatgccttcatatagacatagtctttcagacctctactgtcagttttcatttctagctgctttcagggttttatgaattttcaggcaaagctttaatttatactaagcttaggaagtatggctaatgccaacggcagtttttttcttcttaattccacatgactgaggcatatatgatctctgggtaggtgagttgttgtgacaaccacaagcactttttttttttttaaagaaaaaaaggtagtgaatttttaatcatctggactttaagaaggattctggagtatacttaggcctgaaattatatatatttggcttggaaatgtgtttttcttcaattacatctacaagtaagtacagctgaaattcagaggacccataagagttcacatgaaaaaaatcaatttatttgaaaaggcaagatgcaggagagaggaagccttgcaaacctgcagactgctttttgcccaatatagattgggtaaggctgcaaaacataagcttaattagctcacatgctctgctctcacgtggcaccagtggatagtgtgagagaattaggctgtagaacaaatggccttctctttcagcattcacaccactacaaaatcatcttttatatcaacagaagaataagcataaactaagcaaaaggtcaataagtacctgaaaccaagattggctagagatatatcttaatgcaatccattttctgatggattgttacgagttggctatataatgtatgtatggtattttgatttgtgtaaaagttttaaaaatcaagctttaagtacatggacatttttaaataaaatatttaaagacaatttagaaaattgccttaatatcattgttggctaaatagaataggggacatgcatattaaggaaaaggtcatggagaaataatattggtatcaaacaaatacattgatttgtcatgatacacattgaatttgatccaatagtttaaggaataggtaggaaaatttggtttctatttttcgatttcctgtaaatcagtgacataaataattcttagcttattttatatttccttgtcttaaatactgagctcagtaagttgtgttaggggattatttctcagttgagactttcttatatgacattttactatgttttgacttcctgactattaaaaataaatagtagatacaattttcataaagtgaagaattatataatcactgctttataactgactttattatatttatttcaaagttcatttaaaggctactattcatcctctgtgatggaatggtcaggaatttgttttctcatagtttaattccaacaacaatattagtcgtatccaaaataacctttaatgctaaactttactgatgtatatccaaagcttctcattttcagacagattaatccagaagcagtcataaacagaagaataggtggtatgttcctaatgatattatttctactaatggaataaactgtaatattagaaattatgctgctaattatatcagctctgaggtaatttctgaaatgttcagactcagtcggaacaaattggaaaatttaaatttttattcttagctataaagcaagaaagtaaacacattaatttcctcaacatttttaagccaattaaaaatataaaagatacacaccaatatcttcttcaggctctgacaggcctcctggaaacttccacatatttttcaactgcagtataaagtcagaaaataaagttaacataactttcactaacacacacatatgtagatttcacaaaatccacctataattggtcaaagtggttgagaatatattttttagtaattgcatgcaaaatttttctagcttccatcctttctccctcgtttcttctttttttgggggagctggtaactgatgaaatcttttcccaccttttctcttcaggaaatataagtggttttgtttggttaacgtgatacattctgtatgaatgaaacattggagggaaacatctactgaatttctgtaatttaaaatattttgctgctagttaactatgaacagatagaagaatcttacagatgctgctataaataagtagaaaatataaatttcatcactaaaatatgctattttaaaatctatttcctatattgtatttctaatcagatgtattactcttattatttctattgtatgtgttaatgattttatgtaaaaatgtaattgcttttcatgagtagtatgaataaaattgattagtttgtgttttcttgtctccc
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:2247 -> Molecular function: GO:0005104 [fibroblast growth factor receptor binding] evidence: IPI
GeneID:2247 -> Molecular function: GO:0005125 [cytokine activity] evidence: IDA
GeneID:2247 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:2247 -> Molecular function: GO:0008083 [growth factor activity] evidence: IDA
GeneID:2247 -> Molecular function: GO:0008201 [heparin binding] evidence: IEA
GeneID:2247 -> Molecular function: GO:0017134 [fibroblast growth factor binding] evidence: IEA
GeneID:2247 -> Molecular function: GO:0030374 [ligand-dependent nuclear receptor transcription coactivator activity] evidence: IDA
GeneID:2247 -> Molecular function: GO:0042056 [chemoattractant activity] evidence: IDA
GeneID:2247 -> Biological process: GO:0000186 [activation of MAPKK activity] evidence: IEA
GeneID:2247 -> Biological process: GO:0000187 [activation of MAPK activity] evidence: TAS
GeneID:2247 -> Biological process: GO:0000189 [MAPK import into nucleus] evidence: IEA
GeneID:2247 -> Biological process: GO:0001658 [branching involved in ureteric bud morphogenesis] evidence: IDA
GeneID:2247 -> Biological process: GO:0001759 [organ induction] evidence: IEA
GeneID:2247 -> Biological process: GO:0001938 [positive regulation of endothelial cell proliferation] evidence: IMP
GeneID:2247 -> Biological process: GO:0002042 [cell migration involved in sprouting angiogenesis] evidence: IDA
GeneID:2247 -> Biological process: GO:0002042 [cell migration involved in sprouting angiogenesis] evidence: IGI
GeneID:2247 -> Biological process: GO:0006661 [phosphatidylinositol biosynthetic process] evidence: IDA
GeneID:2247 -> Biological process: GO:0006700 [C21-steroid hormone biosynthetic process] evidence: IEA
GeneID:2247 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:2247 -> Biological process: GO:0006935 [chemotaxis] evidence: TAS
GeneID:2247 -> Biological process: GO:0007165 [signal transduction] evidence: NAS
GeneID:2247 -> Biological process: GO:0007173 [epidermal growth factor receptor signaling pathway] evidence: TAS
GeneID:2247 -> Biological process: GO:0007265 [Ras protein signal transduction] evidence: TAS
GeneID:2247 -> Biological process: GO:0007399 [nervous system development] evidence: TAS
GeneID:2247 -> Biological process: GO:0008284 [positive regulation of cell proliferation] evidence: IGI
GeneID:2247 -> Biological process: GO:0008285 [negative regulation of cell proliferation] evidence: IEA
GeneID:2247 -> Biological process: GO:0008286 [insulin receptor signaling pathway] evidence: TAS
GeneID:2247 -> Biological process: GO:0008543 [fibroblast growth factor receptor signaling pathway] evidence: IDA
GeneID:2247 -> Biological process: GO:0008543 [fibroblast growth factor receptor signaling pathway] evidence: IGI
GeneID:2247 -> Biological process: GO:0008543 [fibroblast growth factor receptor signaling pathway] evidence: IPI
GeneID:2247 -> Biological process: GO:0008543 [fibroblast growth factor receptor signaling pathway] evidence: TAS
GeneID:2247 -> Biological process: GO:0009887 [organ morphogenesis] evidence: TAS
GeneID:2247 -> Biological process: GO:0010001 [glial cell differentiation] evidence: IEA
GeneID:2247 -> Biological process: GO:0010764 [negative regulation of fibroblast migration] evidence: IDA
GeneID:2247 -> Biological process: GO:0010863 [positive regulation of phospholipase C activity] evidence: IDA
GeneID:2247 -> Biological process: GO:0021762 [substantia nigra development] evidence: IEA
GeneID:2247 -> Biological process: GO:0021940 [positive regulation of cerebellar granule cell precursor proliferation] evidence: IEA
GeneID:2247 -> Biological process: GO:0030198 [extracellular matrix organization] evidence: TAS
GeneID:2247 -> Biological process: GO:0030214 [hyaluronan catabolic process] evidence: IDA
GeneID:2247 -> Biological process: GO:0030308 [negative regulation of cell growth] evidence: IEA
GeneID:2247 -> Biological process: GO:0030324 [lung development] evidence: IEA
GeneID:2247 -> Biological process: GO:0032958 [inositol phosphate biosynthetic process] evidence: IDA
GeneID:2247 -> Biological process: GO:0038095 [Fc-epsilon receptor signaling pathway] evidence: TAS
GeneID:2247 -> Biological process: GO:0042060 [wound healing] evidence: TAS
GeneID:2247 -> Biological process: GO:0042660 [positive regulation of cell fate specification] evidence: IDA
GeneID:2247 -> Biological process: GO:0043536 [positive regulation of blood vessel endothelial cell migration] evidence: IDA
GeneID:2247 -> Biological process: GO:0043537 [negative regulation of blood vessel endothelial cell migration] evidence: IDA
GeneID:2247 -> Biological process: GO:0043552 [positive regulation of phosphatidylinositol 3-kinase activity] evidence: IDA
GeneID:2247 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
GeneID:2247 -> Biological process: GO:0045669 [positive regulation of osteoblast differentiation] evidence: IEA
GeneID:2247 -> Biological process: GO:0045765 [regulation of angiogenesis] evidence: TAS
GeneID:2247 -> Biological process: GO:0045766 [positive regulation of angiogenesis] evidence: IDA
GeneID:2247 -> Biological process: GO:0045892 [negative regulation of transcription, DNA-dependent] evidence: IEA
GeneID:2247 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: IDA
GeneID:2247 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:2247 -> Biological process: GO:0046668 [regulation of retinal cell programmed cell death] evidence: IEA
GeneID:2247 -> Biological process: GO:0048011 [neurotrophin TRK receptor signaling pathway] evidence: TAS
GeneID:2247 -> Biological process: GO:0048015 [phosphatidylinositol-mediated signaling] evidence: TAS
GeneID:2247 -> Biological process: GO:0048598 [embryonic morphogenesis] evidence: TAS
GeneID:2247 -> Biological process: GO:0048678 [response to axon injury] evidence: IEA
GeneID:2247 -> Biological process: GO:0048864 [stem cell development] evidence: IEA
GeneID:2247 -> Biological process: GO:0050918 [positive chemotaxis] evidence: IDA
GeneID:2247 -> Biological process: GO:0051209 [release of sequestered calcium ion into cytosol] evidence: IDA
GeneID:2247 -> Biological process: GO:0051726 [regulation of cell cycle] evidence: IEA
GeneID:2247 -> Biological process: GO:0051781 [positive regulation of cell division] evidence: IEA
GeneID:2247 -> Biological process: GO:0060045 [positive regulation of cardiac muscle cell proliferation] evidence: IDA
GeneID:2247 -> Biological process: GO:0060128 [corticotropin hormone secreting cell differentiation] evidence: IEA
GeneID:2247 -> Biological process: GO:0060129 [thyroid-stimulating hormone-secreting cell differentiation] evidence: IEA
GeneID:2247 -> Biological process: GO:0060548 [negative regulation of cell death] evidence: IDA
GeneID:2247 -> Biological process: GO:0060591 [chondroblast differentiation] evidence: IDA
GeneID:2247 -> Biological process: GO:0060644 [mammary gland epithelial cell differentiation] evidence: IEA
GeneID:2247 -> Biological process: GO:0061045 [negative regulation of wound healing] evidence: IDA
GeneID:2247 -> Biological process: GO:0070374 [positive regulation of ERK1 and ERK2 cascade] evidence: IDA
GeneID:2247 -> Cellular component: GO:0005576 [extracellular region] evidence: TAS
GeneID:2247 -> Cellular component: GO:0005615 [extracellular space] evidence: IEA
GeneID:2247 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
GeneID:2247 -> Cellular component: GO:0005829 [cytosol] evidence: IEA
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