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2024-04-25 06:35:39, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001271629 5694 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens myocyte enhancer factor 2D (MEF2D), transcript variant
2, mRNA.
ACCESSION NM_001271629
VERSION NM_001271629.1 GI:410442514
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5694)
AUTHORS She,H., Yang,Q., Shepherd,K., Smith,Y., Miller,G., Testa,C. and
Mao,Z.
TITLE Direct regulation of complex I by mitochondrial MEF2D is disrupted
in a mouse model of Parkinson disease and in human patients
JOURNAL J. Clin. Invest. 121 (3), 930-940 (2011)
PUBMED 21393861
REMARK GeneRIF: direct regulation of complex I by mitochondrial MEF2D
underlies its neuroprotective effects, and dysregulation of this
pathway may contribute to Parkinson disease
REFERENCE 2 (bases 1 to 5694)
AUTHORS Aude-Garcia,C., Collin-Faure,V., Bausinger,H., Hanau,D.,
Rabilloud,T. and Lemercier,C.
TITLE Dual roles for MEF2A and MEF2D during human macrophage terminal
differentiation and c-Jun expression
JOURNAL Biochem. J. 430 (2), 237-244 (2010)
PUBMED 20590529
REMARK GeneRIF: MEF2A and MEF2D play dual roles in human macrophages
differentiation, as activators and as repressors of c-jun
transcription.
REFERENCE 3 (bases 1 to 5694)
AUTHORS Czubryt,M.P., Lamoureux,L., Ramjiawan,A., Abrenica,B.,
Jangamreddy,J. and Swan,K.
TITLE Regulation of cardiomyocyte Glut4 expression by ZAC1
JOURNAL J. Biol. Chem. 285 (22), 16942-16950 (2010)
PUBMED 20363751
REMARK GeneRIF: ZAC1 is a novel and previously unknown regulator of
cardiomyocyte Glut4 expression and glucose uptake; MEF2 is a
regulator of ZAC1 expression in response to induction of
hypertrophy
REFERENCE 4 (bases 1 to 5694)
AUTHORS Yang,Q., She,H., Gearing,M., Colla,E., Lee,M., Shacka,J.J. and
Mao,Z.
TITLE Regulation of neuronal survival factor MEF2D by chaperone-mediated
autophagy
JOURNAL Science 323 (5910), 124-127 (2009)
PUBMED 19119233
REMARK GeneRIF: MEF2D levels were increased in the brains patients with
Parkinson's disease
REFERENCE 5 (bases 1 to 5694)
AUTHORS Liu,G., Han,J., Profirovic,J., Strekalova,E. and
Voyno-Yasenetskaya,T.A.
TITLE Galpha13 regulates MEF2-dependent gene transcription in endothelial
cells: role in angiogenesis
JOURNAL Angiogenesis 12 (1), 1-15 (2009)
PUBMED 19093215
REMARK GeneRIF: MEF2 proteins are an important component in
Galpha13-mediated angiogenesis.
REFERENCE 6 (bases 1 to 5694)
AUTHORS Zhao,M., New,L., Kravchenko,V.V., Kato,Y., Gram,H., di Padova,F.,
Olson,E.N., Ulevitch,R.J. and Han,J.
TITLE Regulation of the MEF2 family of transcription factors by p38
JOURNAL Mol. Cell. Biol. 19 (1), 21-30 (1999)
PUBMED 9858528
REFERENCE 7 (bases 1 to 5694)
AUTHORS Yang,C.C., Ornatsky,O.I., McDermott,J.C., Cruz,T.F. and Prody,C.A.
TITLE Interaction of myocyte enhancer factor 2 (MEF2) with a
mitogen-activated protein kinase, ERK5/BMK1
JOURNAL Nucleic Acids Res. 26 (20), 4771-4777 (1998)
PUBMED 9753748
REFERENCE 8 (bases 1 to 5694)
AUTHORS Ornatsky,O.I. and McDermott,J.C.
TITLE MEF2 protein expression, DNA binding specificity and complex
composition, and transcriptional activity in muscle and non-muscle
cells
JOURNAL J. Biol. Chem. 271 (40), 24927-24933 (1996)
PUBMED 8798771
REFERENCE 9 (bases 1 to 5694)
AUTHORS Hobson,G.M., Krahe,R., Garcia,E., Siciliano,M.J. and Funanage,V.L.
TITLE Regional chromosomal assignments for four members of the MADS
domain transcription enhancer factor 2 (MEF2) gene family to human
chromosomes 15q26, 19p12, 5q14, and 1q12-q23
JOURNAL Genomics 29 (3), 704-711 (1995)
PUBMED 8575763
REFERENCE 10 (bases 1 to 5694)
AUTHORS Breitbart,R.E., Liang,C.S., Smoot,L.B., Laheru,D.A., Mahdavi,V. and
Nadal-Ginard,B.
TITLE A fourth human MEF2 transcription factor, hMEF2D, is an early
marker of the myogenic lineage
JOURNAL Development 118 (4), 1095-1106 (1993)
PUBMED 8269842
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BC040949.1, AL139412.10 and
R42560.1.
Summary: This gene is a member of the myocyte-specific enhancer
factor 2 (MEF2) family of transcription factors. Members of this
family are involved in control of muscle and neuronal cell
differentiation and development, and are regulated by class II
histone deacetylases. Fusions of the encoded protein with Deleted
in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation
have been found in an acute lymphoblastic leukemia cell line,
suggesting a role in leukemogenesis. The encoded protein may also
be involved in Parkinson disease and myotonic dystrophy.
Alternative splicing results in multiple transcript variants.
[provided by RefSeq, Oct 2012].
Transcript Variant: This variant (2) contains an alternate exon and
splice site in the 5' UTR, and lacks an internal in-frame exon in
the coding region, compared to variant 1. The resulting isoform (2,
also known as hMEF2Da0), is shorter than isoform 1.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC040949.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025081, ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-83 BC040949.1 1-83
84-84 AL139412.10 51073-51073 c
85-495 BC040949.1 85-495
496-496 AL139412.10 41505-41505 c
497-969 BC040949.1 497-969
970-970 AL139412.10 37668-37668 c
971-3194 BC040949.1 971-3194
3195-5490 AL139412.10 24471-26766 c
5491-5694 R42560.1 1-204 c
FEATURES Location/Qualifiers
source 1..5694
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q12-q23"
gene 1..5694
/gene="MEF2D"
/note="myocyte enhancer factor 2D"
/db_xref="GeneID:4209"
/db_xref="HGNC:6997"
/db_xref="MIM:600663"
exon 1..88
/gene="MEF2D"
/inference="alignment:Splign:1.39.8"
variation 84
/gene="MEF2D"
/replace="a"
/replace="t"
/db_xref="dbSNP:947660"
exon 89..268
/gene="MEF2D"
/inference="alignment:Splign:1.39.8"
STS 142..317
/gene="MEF2D"
/standard_name="MARC_16813-16814:1033503049:1"
/db_xref="UniSTS:268128"
misc_feature 197..199
/gene="MEF2D"
/note="upstream in-frame stop codon"
variation 203
/gene="MEF2D"
/replace="a"
/replace="c"
/db_xref="dbSNP:28730744"
CDS 215..1759
/gene="MEF2D"
/note="isoform 2 is encoded by transcript variant 2; MADS
box transcription enhancer factor 2, polypeptide D;
myocyte-specific enhancer factor 2D"
/codon_start=1
/product="myocyte-specific enhancer factor 2D isoform 2"
/protein_id="NP_001258558.1"
/db_xref="GI:410442515"
/db_xref="GeneID:4209"
/db_xref="HGNC:6997"
/db_xref="MIM:600663"
/translation="
MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRASEELDGLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLSPQQPALQRNSVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGNSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLNNAQRLGVSQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYETGDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLDTWTLK
"
misc_feature 218..448
/gene="MEF2D"
/note="MEF2 (myocyte enhancer factor 2)-like/Type II
subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF
(serum response factor) box family of eukaryotic
transcriptional regulators. Binds DNA and exists as hetero
and homo-dimers. Differs from SRF-like/Type I...; Region:
MADS_MEF2_like; cd00265"
/db_xref="CDD:29020"
misc_feature order(218..226,230..232,236..238,251..253,257..259,
269..274,281..286,290..295,302..307,311..316,326..328)
/gene="MEF2D"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:29020"
misc_feature order(275..277,296..301,308..313,317..322,329..331,
344..346,350..352,356..358,374..376,380..382,398..400,
407..412,419..421,428..433)
/gene="MEF2D"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:29020"
misc_feature 389..391
/gene="MEF2D"
/note="putative phosphorylation site [posttranslational
modification]; other site"
/db_xref="CDD:29020"
misc_feature 497..679
/gene="MEF2D"
/note="Holliday junction regulator protein family
C-terminal repeat; Region: HJURP_C; pfam12347"
/db_xref="CDD:152782"
misc_feature 575..577
/gene="MEF2D"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by PKA; propagated from
UniProtKB/Swiss-Prot (Q14814.1); phosphorylation site"
misc_feature 752..754
/gene="MEF2D"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by MAPK7; propagated from
UniProtKB/Swiss-Prot (Q14814.1); phosphorylation site"
misc_feature 905..907
/gene="MEF2D"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q14814.1); phosphorylation site"
misc_feature 947..949
/gene="MEF2D"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine; propagated from
UniProtKB/Swiss-Prot (Q14814.1); acetylation site"
misc_feature 965..967
/gene="MEF2D"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q14814.1); phosphorylation site"
misc_feature 1508..1510
/gene="MEF2D"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine, alternate; propagated from
UniProtKB/Swiss-Prot (Q14814.1); acetylation site"
misc_feature 1523..1525
/gene="MEF2D"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
(Q14814.1); phosphorylation site"
STS 215..733
/gene="MEF2D"
/standard_name="Mef2d"
/db_xref="UniSTS:265605"
exon 269..472
/gene="MEF2D"
/inference="alignment:Splign:1.39.8"
STS 370..733
/gene="MEF2D"
/standard_name="Mef2d"
/db_xref="UniSTS:238138"
exon 473..610
/gene="MEF2D"
/inference="alignment:Splign:1.39.8"
exon 611..821
/gene="MEF2D"
/inference="alignment:Splign:1.39.8"
exon 822..878
/gene="MEF2D"
/inference="alignment:Splign:1.39.8"
exon 879..1069
/gene="MEF2D"
/inference="alignment:Splign:1.39.8"
STS 935..1045
/gene="MEF2D"
/standard_name="D1S262E"
/db_xref="UniSTS:147387"
exon 1070..1199
/gene="MEF2D"
/inference="alignment:Splign:1.39.8"
exon 1200..1440
/gene="MEF2D"
/inference="alignment:Splign:1.39.8"
exon 1441..1747
/gene="MEF2D"
/inference="alignment:Splign:1.39.8"
exon 1748..5683
/gene="MEF2D"
/inference="alignment:Splign:1.39.8"
STS 2295..3176
/gene="MEF2D"
/standard_name="MEF2D_2065"
/db_xref="UniSTS:280845"
STS 2852..3009
/gene="MEF2D"
/standard_name="RH70462"
/db_xref="UniSTS:33507"
STS 2966..3178
/gene="MEF2D"
/standard_name="RH81006"
/db_xref="UniSTS:89519"
polyA_site 3187
/gene="MEF2D"
STS 4348..4423
/gene="MEF2D"
/standard_name="1996"
/db_xref="UniSTS:56140"
STS 5459..5674
/gene="MEF2D"
/standard_name="HSC1IB102"
/db_xref="UniSTS:25334"
polyA_signal 5647..5652
/gene="MEF2D"
polyA_site 5683
/gene="MEF2D"
ORIGIN
ggggcctgagaccacccctgccctaggcccagctttcctggactgcctgcccccacaaaccaacagcccgcccccaggtccccagtcgaaggtatcctgcagaccatgaactgagcactgttcccagaccgttcatgagcacagtgtaaggtgtgccgagacccaccacccagcgagcccctcccctccgtagcactgaggacccccggagaagatggggaggaaaaagattcagatccagcgaatcaccgacgagcggaaccgacaggtgactttcaccaagcggaagtttggcctgatgaagaaggcgtatgagctgagcgtgctatgtgactgcgagatcgcactcatcatcttcaaccactccaacaagctgttccagtacgccagcaccgacatggacaaggtgctgctcaagtacacggagtacaatgagccacacgagagccgcaccaacgccgacatcatcgagaccctgaggaagaagggcttcaacggctgcgacagccccgagcccgacggggaggactcgctggaacagagccccctgctggaggacaagtaccgacgcgccagcgaggagctcgacgggctcttccggcgctatgggtcaactgtcccggcccccaactttgccatgcctgtcacggtgcccgtgtccaatcagagctcactgcagttcagcaatcccagcggctccctggtcaccccttccctggtgacatcatccctcacggacccgcggctcctgtccccccagcagccagcactacagaggaacagtgtgtctcctggcctgccccagcggccagctagtgcgggggccatgctggggggtgacctgaacagtgctaacggagcctgccccagccctgttgggaatggctacgtcagtgctcgggcttcccctggcctcctccctgtggccaatggcaacagcctaaacaaggtcatccctgccaagtctccacccccacctacccacagcacccagcttggagcccccagccgcaagcccgacctgcgagtcatcacttcccaggcaggaaaggggttaatgcatcacttgaacaatgcccagcgccttggggtctcccagtctactcattcgctcaccaccccagtggtttctgtggcaacgccgagtttactcagccagggcctccccttctcttccatgcccactgcctacaacacagattaccagttgaccagtgcagagctctcctccttaccagcctttagttcacctggggggctgtcgctaggcaatgtcactgcctggcaacagccacagcagccccagcagccgcagcagccacagcctccacagcagcagccaccgcagccacagcagccacagccacagcagcctcagcagccgcaacagccacctcagcaacagtcccacctggtccctgtatctctcagcaacctcatcccgggcagccccctgccccacgtgggtgctgccctcacagtcaccacccacccccacatcagcatcaagtcagaaccggtgtccccaagccgtgagcgcagccctgcgcctccccctccagctgtgttcccagctgcccgccctgagcctggcgatggtctcagcagcccagccgggggatcctatgagacgggagaccgggatgacggacggggggacttcgggcccacactgggcctgctgcgcccagccccagagcctgaggctgagggctcagctgtgaagaggatgcggcttgatacctggacattaaagtgacgattcccactcccctcctctcagcctccctgatgaagagttgacaatctcaccgcccgcccttccctgccccgggctcctcccgctcgacccccacttcctttcttgtgcttcgtgtcctgttgacggttacatttgtgtataattattatattattattattattattatattttttttaatttggattctcgctttggagagggggatgctctcatcccctctttctgtaccccccaccattttcactggctggggggctctctttttcgcgggaaggggggacactttgcacgttgtacacatatgctgcaggaagggggtggggggcccaataaggcctttgggaaaggacaggtgccgagccctgcatgtggagccctcccaccccacccccagatagagggaaataaccaaaaaactaccaaacaacagaaacccacactctagactgaaaccccaaagtgggcttgatgggtgggtttgtgtttcaaggggaaagtgaggcagaggttctgaaaagggtctctgtttttgtgttcatgtagccataggcacatggagcagaatacttaagcctggcccccaaatgcccctgcacacacacgtgccacacctgcgctgattcttgtgtgtgctgcacccccaaggtgtgtgggtgctggctgagctttgggccgggaaggcagcctgggaatctgaggctggagacaggggtttgaggtgggggcctctctggaagcacatttggagggaaagacaagagagccatgaggagagggctgaggagggcagaagggctaggcagggggcaaattgagcccctcccttccccagtttttctctaagatatacagtgcaatagctccccacccctcagttgacgccagccctgtaaagctggccacagtgtgcagggagaatggggagagggtcttcagtgaggtggctggggcgagagtcggcctggacttccctggggtgctccaggccagagctctttcattggggcgagtgtggtgaggggacgtccttggtcttgcacgcacactacctgggggagtcaacactgggatggtctgtggggtgggagggcctacggatgggtccgtagaggtcccacctccctcattcctccttggcccctctccctagcttctcctgttagctccttctgctcctgaccccacctccttgctcttggcgcccctattgtctctggctacctccttgtcccaccacctccaggctgcatcccaccttccctcttggctactgtaattgtaaatagcgacctttggaaaacgttagcggtgtaacagtccaggaaactgtttttttttgttgttgttgtattgatatgaaatgagattctatttttgtcaaagtatattgtaataataatgactcaaacggcccgtactgtacagacgagattcttctgctgttgttcttgctcccctcccctcctctgagtccgcccctccctgctgcctcctcagtggggcagtgggcaaggggcccaggggcagccgaagcacggggtcctgagacctcaggcaggattggagatcaaaccagagggggcaggcccccagcctgctctctaggatcaccccccgccctaaggggcctggcctggggtgacgtggccaggcagactgtctgccccactccttcacacaagcccagctcctctgcccaaggggtgcggcgcccccttggggtttcctcccagttggagagtagagttaagacaaggcccagttttgtgttagccgaccgtctttgcccacctctatgacccagcctcttgcagtattcccatacttgatgcagggaaggaaccagaagcagaggggcctctacgcaggtacacacgtgtacctgagtgtgttcatgagggcatctggtgtttatgtgtctgagtgtagctttgtatttatgtgtgtgtgtgtgtgtatgtctgattgcacgggtgtacttttgtatttatgtgtgtgtgtggttgcacgggtgtgcctctgtgtgtctctgaccctggctgggtgtgtgtgcaaatctgtgtgactggagctctaggggcatctctgtgtctgagtgtgcctggtgtgtgtttacaaagggagagttggctgctccagctccacagccctgggaccccaactcctgtcttccctgctcctttccctgtgttcaccctcagctctgacacattgaactgcagttggggggattggcagttagccctctgtgcttctccctgcagccctacctctgccaaggtctctccctccagggacctctgcttccacccacatatgtccacttagtcacccacacttgacacagttcctggagtaccctcttcccccaaccccagacctgctttcagagcaaaactcaagtccctcttcctccgtgaagcttctccctcagctgagcagtgatcacttactcactcttaaccccaatccgctgactgggtggggacagcacgtccagccttcccacctctcctgcaggcttctagacggagtttcaaaaactgatgagcctcgatccagggcttgaaagaagccagggtgtaatcttgttcatgcatgcgtccccagagcctcgcccagtgcctggcacatagtaggcactcaataaatgctgaatgggtgaatagttgaatgataggtgctcaataaatgaatgaatggccttcccttctcaggctattcccaccattagtctgcccacctttctaggctgggcttggccaccattaaacacggggtgggggtgagggcccctgcaattcacggtgcaatattcaccagttttgccctctgcctcataaaggcaaacctggcttttgattaccatgtgtggatgtttcagtgtcctttcttctctgtccctggggatggggtggtctgtgaatatgtgacatttctgcagttcagtatccgaaggtttctcttgggggtaggggctcctgggcggccagatgaatgggtccctgggaacccagacctcagatgaggacttaatgtcttcttcctctcaagccaaattcgcctccacccactccctctgaagaactgggcatttgccaaagtaaccactggagtcatctaatggccctccccctccccaggtttcccacagctttcagggacagtgggcaagaggacacccccccccaccacctcagtggaacacaccattctccccccctcaacagcacactcagtgcagcaagactgacccctgaccccctcccagccctccctaccttggacaggaaggaagtaatgcaccttctcttgctgattatttatttgtttggagagacagaaatgtaaaagtgtatctagaaatatctatatctctatatatttttaactgactctttggaatcccctggggtggggtgaggggtaagtttaggctttcgcggaggggaggagacatggagcctgggaactccttgttctcccctctgctgcctctccccaccccttaaagcagttggtagaaggaatggtatttgtatggggggagggaggctggaatggagaatctggattctctcctcttccccattctccagagggagggaggtggtgaggaagaggaagggaggggcaggatgggccatggaggtgccccacccccacacctgacaatcacccacactcctggggctcttcctgggtcctggggcagggcgagtccaagtgtgaggctgttgatttgttttcaatatttcttttcgtgctgtatggtgatgctttcttagtattctacacaataagaaaagacaaagtcctcgagattcttatgagttttgtttgaaaactctttcactatatttgttgtaaagaggtttactattaaaagaaaaagaatacacgtttctgatacttcggaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:4209 -> Molecular function: GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] evidence: IDA
GeneID:4209 -> Molecular function: GO:0000981 [sequence-specific DNA binding RNA polymerase II transcription factor activity] evidence: IDA
GeneID:4209 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: NAS
GeneID:4209 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:4209 -> Molecular function: GO:0033613 [activating transcription factor binding] evidence: IPI
GeneID:4209 -> Molecular function: GO:0042826 [histone deacetylase binding] evidence: IPI
GeneID:4209 -> Molecular function: GO:0046983 [protein dimerization activity] evidence: IEA
GeneID:4209 -> Biological process: GO:0001649 [osteoblast differentiation] evidence: IEA
GeneID:4209 -> Biological process: GO:0001958 [endochondral ossification] evidence: IEA
GeneID:4209 -> Biological process: GO:0002062 [chondrocyte differentiation] evidence: IEA
GeneID:4209 -> Biological process: GO:0006366 [transcription from RNA polymerase II promoter] evidence: IDA
GeneID:4209 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:4209 -> Biological process: GO:0007399 [nervous system development] evidence: IEA
GeneID:4209 -> Biological process: GO:0007512 [adult heart development] evidence: IEP
GeneID:4209 -> Biological process: GO:0007517 [muscle organ development] evidence: TAS
GeneID:4209 -> Biological process: GO:0035914 [skeletal muscle cell differentiation] evidence: IEA
GeneID:4209 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:4209 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:4209 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
GeneID:4209 -> Cellular component: GO:0043231 [intracellular membrane-bounded organelle] evidence: IDA
by
@meso_cacase at
DBCLS
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