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2024-03-29 21:02:42, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001271282            6192 bp    mRNA    linear   PRI 24-JUN-2013
DEFINITION  Homo sapiens dicer 1, ribonuclease type III (DICER1), transcript
            variant 4, mRNA.
ACCESSION   NM_001271282
VERSION     NM_001271282.1  GI:404312695
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6192)
  AUTHORS   Redfern,A.D., Colley,S.M., Beveridge,D.J., Ikeda,N., Epis,M.R.,
            Li,X., Foulds,C.E., Stuart,L.M., Barker,A., Russell,V.J.,
            Ramsay,K., Kobelke,S.J., Li,X., Hatchell,E.C., Payne,C.,
            Giles,K.M., Messineo,A., Gatignol,A., Lanz,R.B., O'Malley,B.W. and
            Leedman,P.J.
  TITLE     RNA-induced silencing complex (RISC) Proteins PACT, TRBP, and Dicer
            are SRA binding nuclear receptor coregulators
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 110 (16), 6536-6541 (2013)
   PUBMED   23550157
  REMARK    GeneRIF: RISC proteins PACT, TRBP, and Dicer, together with PKR,
            are steroid receptor RNA activator-binding nuclear receptor
            coregulators that are recruited to the promoters of
            hormone-regulated genes and regulate the expression of downstream
            target genes.
REFERENCE   2  (bases 1 to 6192)
  AUTHORS   Vincenzi,B., Zoccoli,A., Schiavon,G., Iuliani,M., Pantano,F.,
            Dell'aquila,E., Ratta,R., Muda,A.O., Perrone,G., Brunelli,C.,
            Correale,P., Riva,E., Russo,A., Loupakis,F., Falcone,A., Santini,D.
            and Tonini,G.
  TITLE     Dicer and Drosha expression and response to Bevacizumab-based
            therapy in advanced colorectal cancer patients
  JOURNAL   Eur. J. Cancer 49 (6), 1501-1508 (2013)
   PUBMED   23266047
  REMARK    GeneRIF: Data indicate that tumour sample showed a significantly
            higher Drosha expression versus normal mucosa, while Dicer levels
            did not differ.
REFERENCE   3  (bases 1 to 6192)
  AUTHORS   Velez Edwards,D.R., Naj,A.C., Monda,K., North,K.E., Neuhouser,M.,
            Magvanjav,O., Kusimo,I., Vitolins,M.Z., Manson,J.E.,
            O'Sullivan,M.J., Rampersaud,E. and Edwards,T.L.
  TITLE     Gene-environment interactions and obesity traits among
            postmenopausal African-American and Hispanic women in the Women's
            Health Initiative SHARe Study
  JOURNAL   Hum. Genet. 132 (3), 323-336 (2013)
   PUBMED   23192594
REFERENCE   4  (bases 1 to 6192)
  AUTHORS   Oshlag,J.Z., Devasthanam,A.S. and Tomasi,T.B.
  TITLE     Mild hyperthermia enhances the expression and induces oscillations
            in the Dicer protein
  JOURNAL   Int J Hyperthermia 29 (1), 51-61 (2013)
   PUBMED   23311378
  REMARK    GeneRIF: Heat-induced regulation of Dicer expression occurs
            primarily post- transcriptionally, and the expression levels of
            Dicer protein are increased and often oscillate in response to
            fever-range hyperthermia in multiple mouse and human cells
REFERENCE   5  (bases 1 to 6192)
  AUTHORS   Li,X., Tian,X., Zhang,B., Zhang,Y. and Chen,J.
  TITLE     Variation in dicer gene is associated with increased survival in
            T-cell lymphoma
  JOURNAL   PLoS ONE 7 (12), E51640 (2012)
   PUBMED   23251602
  REMARK    GeneRIF: Dicer rs3742330 is associated with T cell lymphoma
            survival.
REFERENCE   6  (bases 1 to 6192)
  AUTHORS   Provost,P., Dishart,D., Doucet,J., Frendewey,D., Samuelsson,B. and
            Radmark,O.
  TITLE     Ribonuclease activity and RNA binding of recombinant human Dicer
  JOURNAL   EMBO J. 21 (21), 5864-5874 (2002)
   PUBMED   12411504
  REMARK    GeneRIF: cloning and expression of the 218 kDa human Dicer, and
            characterization of its ribonuclease activity and dsRNA-binding
            properties
REFERENCE   7  (bases 1 to 6192)
  AUTHORS   Tabara,H., Yigit,E., Siomi,H. and Mello,C.C.
  TITLE     The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a
            DExH-box helicase to direct RNAi in C. elegans
  JOURNAL   Cell 109 (7), 861-871 (2002)
   PUBMED   12110183
REFERENCE   8  (bases 1 to 6192)
  AUTHORS   Suk,K., Kim,S., Kim,Y.H., Oh,S.H., Lee,M.K., Kim,K.W., Kim,H.D. and
            Seo,Y.S.
  TITLE     Identification of a novel human member of the DEAD box protein
            family
  JOURNAL   Biochim. Biophys. Acta 1501 (1), 63-69 (2000)
   PUBMED   10727850
REFERENCE   9  (bases 1 to 6192)
  AUTHORS   Matsuda,S., Ichigotani,Y., Okuda,T., Irimura,T., Nakatsugawa,S. and
            Hamaguchi,M.
  TITLE     Molecular cloning and characterization of a novel human gene
            (HERNA) which encodes a putative RNA-helicase
  JOURNAL   Biochim. Biophys. Acta 1490 (1-2), 163-169 (2000)
   PUBMED   10786632
REFERENCE   10 (bases 1 to 6192)
  AUTHORS   Provost,P., Samuelsson,B. and Radmark,O.
  TITLE     Interaction of 5-lipoxygenase with cellular proteins
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 96 (5), 1881-1885 (1999)
   PUBMED   10051563
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AJ132261.2 and AL390254.6.
            
            Summary: This gene encodes a protein possessing an RNA helicase
            motif containing a DEXH box in its amino terminus and an RNA motif
            in the carboxy terminus. The encoded protein functions as a
            ribonuclease and is required by the RNA interference and small
            temporal RNA (stRNA) pathways to produce the active small RNA
            component that represses gene expression. Alternative splicing
            results in multiple transcript variants. [provided by RefSeq, Sep
            2010].
            
            Transcript Variant: This variant (4) differs in the 5' UTR compared
            to variant 1. Variants 1, 2, and 4 encode the same isoform.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ132261.2 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           ERS025081, ERS025082 [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6089              AJ132261.2         9-6097
            6090-6090           AL390254.6         9579-9579
            6091-6192           AJ132261.2         6099-6200
FEATURES             Location/Qualifiers
     source          1..6192
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q32.13"
     gene            1..6192
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="dicer 1, ribonuclease type III"
                     /db_xref="GeneID:23405"
                     /db_xref="HGNC:17098"
                     /db_xref="MIM:606241"
     exon            1..188
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(21)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139513971"
     variation       complement(80)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:184480459"
     variation       complement(144)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:192166518"
     variation       complement(172)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:77127618"
     exon            189..377
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(214)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370105837"
     misc_feature    231..233
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="upstream in-frame stop codon"
     variation       complement(231)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200884347"
     CDS             234..6002
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /EC_number="3.1.26.-"
                     /note="isoform 1 is encoded by transcript variant 4;
                     K12H4.8-LIKE; helicase-moi; dicer 1, double-stranded
                     RNA-specific endoribonuclease; helicase with RNAse motif;
                     endoribonuclease Dicer; helicase MOI; Dicer1, Dcr-1
                     homolog"
                     /codon_start=1
                     /product="endoribonuclease Dicer isoform 1"
                     /protein_id="NP_001258211.1"
                     /db_xref="GI:404312696"
                     /db_xref="CCDS:CCDS9931.1"
                     /db_xref="GeneID:23405"
                     /db_xref="HGNC:17098"
                     /db_xref="MIM:606241"
                     /translation="
MKSPALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFSRNGKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSNLEVNASWTKERWNQEFTKHQVLIMTCYVALNVLKNGYLSLSDINLLVFDECHLAILDHPYREIMKLCENCPSCPRILGLTASILNGKCDPEELEEKIQKLEKILKSNAETATDLVVLDRYTSQPCEIVVDCGPFTDRSGLYERLLMELEEALNFINDCNISVHSKERDSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTFLRKIHALCEEHFSPASLDLKFVTPKVIKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDEDEEIEEKEKPETNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEAEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYIMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSVDTGETDIDPVMDDDDVFPPYVLRPDDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPDGTFYSTLYLPINSPLRASIVGPPMSCVRLAERVVALICCEKLHKIGELDDHLMPVGKETVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRDSYPRPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFMLSLQMLELITRLHQYIFSHILRLEKPALEFKPTDADSAYCVLPLNVVNDSSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGVGVRSLPADFRYPNLDFGWKKSIDSKSFISISNSSSAENDNYCKHSTIVPENAAHQGANRTSSLENHDQMSVNCRTLLSESPGKLHVEVSADLTAINGLSYNQNLANGSYDLANRDFCQGNQLNYYKQEIPVQPTTSYSIQNLYSYENQPQPSDECTLLSNKYLDGNANKSTSDGSPVMAVMPGTTDTIQVLKGRMDSEQSPSIGYSSRTLGPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNWLPPGYVVNQDKSNTDKWEKDEMTKDCMLANGKLDEDYEEEDEEEESLMWRAPKEEADYEDDFLEYDQEHIRFIDNMLMGSGAFVKKISLSPFSTTDSAYEWKMPKKSSLGSMPFSSDFEDFDYSSWDAMCYLDPSKAVEEDDFVVGFWNPSEENCGVDTGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTDREKALCPTRENFNSQQKNLSVSCAAASVASSRSSVLKDSEYGCLKIPPRCMFDHPDADKTLNHLISGFENFEKKINYRFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVQFQLEKNEMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLETVWQVYYPMMRPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDGKVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLKANQPQVPNS
"
     misc_feature    405..860
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="DEAD-like helicases superfamily. A diverse family
                     of proteins involved in ATP-dependent RNA or DNA
                     unwinding. This domain contains the ATP-binding region;
                     Region: DEXDc; cd00046"
                     /db_xref="CDD:28927"
     misc_feature    432..446
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:28927"
     misc_feature    756..767
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UPY3.3);
                     Region: DECH box"
     misc_feature    756..767
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="putative Mg++ binding site [ion binding]; other
                     site"
                     /db_xref="CDD:28927"
     misc_feature    999..2018
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UPY3.3);
                     Region: Required for interaction with PRKRA and TARBP2"
     misc_feature    1470..1472
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q9UPY3.3); phosphorylation site"
     misc_feature    1476..1478
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q9UPY3.3); phosphorylation site"
     misc_feature    <1563..1892
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="Helicase superfamily c-terminal domain; associated
                     with DEXDc-, DEAD-, and DEAH-box proteins, yeast
                     initiation factor 4A, Ski2p, and Hepatitis C virus NS3
                     helicases; this domain is found in a wide variety of
                     helicases and helicase related proteins; may...; Region:
                     HELICc; cd00079"
                     /db_xref="CDD:28960"
     misc_feature    order(1578..1589,1677..1682,1788..1796)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="nucleotide binding region [chemical binding]; other
                     site"
                     /db_xref="CDD:28960"
     misc_feature    order(1812..1814,1875..1877,1887..1889)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="ATP-binding site [chemical binding]; other site"
                     /db_xref="CDD:28960"
     misc_feature    2121..2399
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="Double stranded RNA binding domain; Region:
                     dsRNA_bind; pfam03368"
                     /db_xref="CDD:190615"
     misc_feature    2889..3257
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="PAZ domain, dicer_like subfamily. Dicer is an RNAse
                     involved in cleaving dsRNA in the RNA interference
                     pathway. It generates dsRNAs which are approximately 20 bp
                     long (siRNAs), which in turn target hydrolysis of
                     homologous RNAs. PAZ domains are named...; Region:
                     PAZ_dicer_like; cd02843"
                     /db_xref="CDD:30328"
     misc_feature    order(3078..3080,3117..3119,3135..3137,3147..3149,
                     3201..3203,3225..3227,3231..3233)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:30328"
     misc_feature    3279..3281
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q9UPY3.3); phosphorylation site"
     misc_feature    4110..>4331
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="dsRNA-specific ribonuclease [Transcription];
                     Region: Rnc; COG0571"
                     /db_xref="CDD:30916"
     misc_feature    4119..>4361
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="RIBOc. Ribonuclease III C terminal domain. This
                     group consists of eukaryotic, bacterial and archeal
                     ribonuclease III (RNAse III) proteins. RNAse III is a
                     double stranded RNA-specific endonuclease. Prokaryotic
                     RNAse III is important in...; Region: RIBOc; cd00593"
                     /db_xref="CDD:29697"
     misc_feature    order(4170..4175,4182..4187,4194..4196,4203..4208,
                     4215..4220,4224..4232,4260..4262)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29697"
     misc_feature    order(4170..4172,4179..4181,4191..4193)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="active site"
                     /db_xref="CDD:29697"
     misc_feature    5274..5771
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="RIBOc. Ribonuclease III C terminal domain. This
                     group consists of eukaryotic, bacterial and archeal
                     ribonuclease III (RNAse III) proteins. RNAse III is a
                     double stranded RNA-specific endonuclease. Prokaryotic
                     RNAse III is important in...; Region: RIBOc; cd00593"
                     /db_xref="CDD:29697"
     misc_feature    order(5337..5342,5349..5354,5361..5363,5370..5375,
                     5382..5387,5391..5399,5427..5429,5691..5693,5724..5726)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29697"
     misc_feature    order(5337..5339,5346..5348,5358..5360,5661..5663,
                     5670..5672)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="active site"
                     /db_xref="CDD:29697"
     misc_feature    order(5346..5348,5661..5663,5670..5672)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:29697"
     misc_feature    5649..5651
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="Important for activity (By similarity); propagated
                     from UniProtKB/Swiss-Prot (Q9UPY3.3); other site"
     variation       complement(253)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:117358479"
     variation       complement(292)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147660793"
     variation       complement(310)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201358110"
     variation       complement(316)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:61729796"
     variation       complement(361)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367797765"
     exon            378..540
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(445)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376657431"
     variation       complement(453)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:202181696"
     variation       complement(454)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200331768"
     variation       complement(479)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:111483821"
     variation       complement(481)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373646414"
     variation       complement(509)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370551656"
     exon            541..671
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(575)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373926076"
     variation       complement(599)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368741914"
     variation       complement(607)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377669634"
     variation       complement(609)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373734886"
     variation       complement(665)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370784723"
     exon            672..806
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(695)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199737359"
     variation       complement(714)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373532001"
     variation       complement(718)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142815547"
     variation       complement(766)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201239474"
     variation       complement(772)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375454363"
     variation       complement(785)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148530092"
     exon            807..967
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(822)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375689793"
     variation       complement(872)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370474705"
     variation       complement(929)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147505764"
     exon            968..1136
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(972)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369189695"
     variation       complement(980)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376070315"
     variation       complement(1004)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:12432511"
     variation       complement(1006)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:188327838"
     variation       complement(1130)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201842071"
     exon            1137..1609
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1153)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149718671"
     variation       complement(1157)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142397473"
     variation       complement(1350)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369145814"
     variation       complement(1357)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:148758903"
     variation       complement(1376)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372592852"
     variation       complement(1408)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142635816"
     variation       complement(1466)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111595160"
     variation       complement(1482)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150714784"
     variation       complement(1593)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368535616"
     variation       complement(1595)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201615540"
     exon            1610..1742
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1614)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141163928"
     variation       complement(1616)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202029334"
     variation       complement(1699)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200866760"
     variation       complement(1729)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:4566088"
     variation       1740
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:137852977"
     exon            1743..1985
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1776)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148218787"
     variation       complement(1816)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143099538"
     variation       1863
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:137852979"
     variation       complement(1864)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143533680"
     variation       complement(1893)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148532788"
     variation       complement(1902)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139198222"
     variation       complement(1914)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147493562"
     variation       complement(1924)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201298288"
     variation       complement(1925)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143117334"
     exon            1986..2140
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1991)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368558276"
     variation       complement(2033)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199995391"
     variation       complement(2058)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:114947750"
     variation       complement(2060)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150087634"
     variation       complement(2070)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201553563"
     variation       complement(2072)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147754242"
     variation       complement(2110)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375579739"
     variation       complement(2120)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141651702"
     exon            2141..2273
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(2168)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61751177"
     variation       complement(2186)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199678028"
     variation       complement(2212)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151272381"
     variation       complement(2252)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:12437122"
     variation       complement(2265)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:377269341"
     variation       complement(2271)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201883449"
     exon            2274..2349
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(2281)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:373914672"
     variation       complement(2282)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:368736189"
     variation       complement(2283)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142300389"
     variation       complement(2332)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376691754"
     variation       complement(2348)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140087741"
     exon            2350..2489
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(2351)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191755360"
     variation       complement(2408)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377025998"
     variation       complement(2429)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146475655"
     variation       complement(2432)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201668559"
     exon            2490..2669
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(2594)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367950170"
     variation       complement(2603)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112712209"
     exon            2670..2883
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(2723)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139444980"
     variation       2749
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:387906934"
     variation       complement(2769)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201212908"
     variation       complement(2786)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373715574"
     variation       complement(2790)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61729795"
     variation       complement(2808)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144649926"
     variation       complement(2847)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149242330"
     exon            2884..3037
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(2893)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:139441077"
     variation       complement(2922)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373729361"
     variation       complement(2950)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150510758"
     variation       complement(2951)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370692165"
     variation       complement(2953)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200408568"
     variation       complement(2985)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:377326167"
     exon            3038..3220
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       3063
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:137852978"
     variation       complement(3131)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375772460"
     variation       complement(3210)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112390607"
     exon            3221..3326
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(3230)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:12018992"
     variation       complement(3266)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:8019857"
     exon            3327..3502
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(3431)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:114964211"
     variation       complement(3446)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148959399"
     variation       complement(3462)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373412959"
     variation       complement(3467)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148166836"
     variation       complement(3493)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:180918578"
     variation       complement(3494)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369869162"
     variation       complement(3497)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:376110719"
     exon            3503..4283
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(3571)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:143841809"
     variation       complement(3625)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200651335"
     variation       complement(3660)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375211466"
     variation       complement(3661)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139786661"
     variation       complement(3695)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:192822778"
     variation       complement(3698)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377272036"
     variation       complement(3707)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368984998"
     variation       complement(3708)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145693584"
     variation       complement(3724..3725)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:34141151"
     variation       complement(3728)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372581591"
     variation       complement(3729)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368588781"
     variation       complement(3785)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375535900"
     variation       complement(3786)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150514959"
     variation       complement(3790)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201523588"
     variation       complement(3800)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141288912"
     variation       complement(3818)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372344332"
     variation       complement(3861)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200925349"
     variation       complement(3907)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146584765"
     variation       complement(3908)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:184830847"
     variation       complement(3997)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:199526737"
     variation       complement(4006)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144095207"
     variation       complement(4024)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139346443"
     variation       complement(4030)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:368610812"
     variation       complement(4048)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151197809"
     variation       complement(4053)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:142193936"
     variation       complement(4071)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148696745"
     variation       complement(4089)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:111495226"
     variation       complement(4092)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373980178"
     variation       complement(4172)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191567701"
     variation       complement(4201)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:35252236"
     variation       complement(4205)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:45562437"
     variation       complement(4220)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373810197"
     variation       complement(4223)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202227142"
     variation       complement(4247)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143454689"
     exon            4284..4439
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(4334)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370897400"
     variation       complement(4363..4364)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:34678453"
     variation       complement(4432)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139536688"
     exon            4440..5328
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(4440)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:147391538"
     variation       complement(4478)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373735840"
     variation       complement(4514)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143985382"
     variation       complement(4529)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146679273"
     variation       complement(4610)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138250984"
     variation       complement(4639)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200890670"
     variation       complement(4656)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150883389"
     variation       complement(4665)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372496188"
     variation       complement(4670)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141556323"
     variation       complement(4708)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370947079"
     variation       complement(4748)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141308332"
     variation       complement(4798)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113234676"
     variation       complement(4808)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:189516161"
     STS             4872..5362
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /standard_name="Dicer1"
                     /db_xref="UniSTS:498692"
     variation       complement(4880)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201415999"
     variation       complement(4908)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377409989"
     variation       complement(4913)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61729797"
     variation       complement(4931)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372837448"
     variation       complement(4952)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141265948"
     variation       complement(4973)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369465519"
     variation       4981
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:137852976"
     variation       complement(5006)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138308365"
     variation       complement(5035)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:181018393"
     variation       complement(5037)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145669719"
     variation       complement(5038)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:148955573"
     variation       complement(5040)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201320420"
     variation       complement(5052)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189119295"
     variation       complement(5053)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368963384"
     variation       complement(5086)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377205344"
     variation       complement(5103)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372967646"
     variation       complement(5122)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368343829"
     variation       complement(5124)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:145551486"
     variation       complement(5129)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376515225"
     variation       complement(5134)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149723645"
     variation       complement(5143)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140875148"
     variation       complement(5178)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146715213"
     variation       complement(5219)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371564184"
     variation       complement(5260)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:375465466"
     variation       complement(5285)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145027662"
     exon            5329..5597
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(5378)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139500905"
     variation       complement(5417)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:202004554"
     variation       complement(5423)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371759757"
     variation       complement(5436)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188609628"
     variation       complement(5474)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114861074"
     variation       complement(5489)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373750374"
     variation       complement(5509)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144259142"
     variation       complement(5562)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183879938"
     variation       complement(5570)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111630745"
     exon            5598..5760
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(5609)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:17191079"
     variation       complement(5627)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201134588"
     variation       complement(5704)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:377685186"
     variation       complement(5740)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:187288681"
     exon            5761..5836
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(5783)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377325189"
     exon            5837..6174
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(5876)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199574382"
     variation       complement(6022)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200095508"
     variation       complement(6068)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191996364"
     variation       complement(6090)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:13078"
     variation       complement(6136)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140021568"
     variation       complement(6168)
                     /gene="DICER1"
                     /gene_synonym="DCR1; Dicer; HERNA; MNG1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112795042"
ORIGIN      
gctggtttcatcctaaggctggatcttttcatgggtctgtgtagtgtaattgcagcagcaaatgggactaataatttcatgagtcatctttagagggaaagaaagacaactgcttctcttcaaccatcaaatgaaagtcctaaattttttgctgttggatgagcatgaaccaattcctctggccagggtaagctgtgctagaacaaaaatgcaatgaaagaaacactggatgaatgaaaagccctgctttgcaacccctcagcatggcaggcctgcagctcatgacccctgcttcctcaccaatgggtcctttctttggactgccatggcaacaagaagcaattcatgataacatttatacgccaagaaaatatcaggttgaactgcttgaagcagctctggatcataataccatcgtctgtttaaacactggctcagggaagacatttattgcagtactactcactaaagagctgtcctatcagatcaggggagacttcagcagaaatggaaaaaggacggtgttcttggtcaactctgcaaaccaggttgctcaacaagtgtcagctgtcagaactcattcagatctcaaggttggggaatactcaaacctagaagtaaatgcatcttggacaaaagagagatggaaccaagagtttactaagcaccaggttctcattatgacttgctatgtcgccttgaatgttttgaaaaatggttacttatcactgtcagacattaaccttttggtgtttgatgagtgtcatcttgcaatcctagaccacccctatcgagaaattatgaagctctgtgaaaattgtccatcatgtcctcgcattttgggactaactgcttccattttaaatgggaaatgtgatccagaggaattggaagaaaagattcagaaactagagaaaattcttaagagtaatgctgaaactgcaactgacctggtggtcttagacaggtatacttctcagccatgtgagattgtggtggattgtggaccatttactgacagaagtgggctttatgaaagactgctgatggaattagaagaagcacttaattttatcaatgattgtaatatatctgtacattcaaaagaaagagattctactttaatttcgaaacagatactatcagactgtcgtgccgtattggtagttctgggaccctggtgtgcagataaagtagctggaatgatggtaagagaactacagaaatacatcaaacatgagcaagaggagctgcacaggaaatttttattgtttacagacactttcctaaggaaaatacatgcactatgtgaagagcacttctcacctgcctcacttgacctgaaatttgtaactcctaaagtaatcaaactgctcgaaatcttacgcaaatataaaccatatgagcgacagcagtttgaaagcgttgagtggtataataatagaaatcaggataattatgtgtcatggagtgattctgaggatgatgatgaggatgaagaaattgaagaaaaagagaagccagagacaaattttccttctccttttaccaacattttgtgcggaattatttttgtggaaagaagatacacagcagttgtcttaaacagattgataaaggaagctggcaaacaagatccagagctggcttatatcagtagcaatttcataactggacatggcattgggaagaatcagcctcgcaacaaacagatggaagcagaattcagaaaacaggaagaggtacttaggaaatttcgagcacatgagaccaacctgcttattgcaacaagtattgtagaagagggtgttgatataccaaaatgcaacttggtggttcgttttgatttgcccacagaatatcgatcctatgttcaatctaaaggaagagcaagggcacccatctctaattatataatgttagcggatacagacaaaataaaaagttttgaagaagaccttaaaacctacaaagctattgaaaagatcttgagaaacaagtgttccaagtcggttgatactggtgagactgacattgatcctgtcatggatgatgatgacgttttcccaccatatgtgttgaggcctgacgatggtggtccacgagtcacaatcaacacggccattggacacatcaatagatactgtgctagattaccaagtgatccgtttactcatctagctcctaaatgcagaacccgagagttgcctgatggtacattttattcaactctttatctgccaattaactcacctcttcgagcctccattgttggtccaccaatgagctgtgtacgattggctgaaagagttgtagctctcatttgctgtgagaaactgcacaaaattggcgaactggatgaccatttgatgccagttgggaaagagactgttaaatatgaagaggagcttgatttgcatgatgaagaagagaccagtgttccaggaagaccaggttccacgaaacgaaggcagtgctacccaaaagcaattccagagtgtttgagggatagttatcccagacctgatcagccctgttacctgtatgtgataggaatggttttaactacacctttacctgatgaactcaactttagaaggcggaagctctatcctcctgaagataccacaagatgctttggaatactgacggccaaacccatacctcagattccacactttcctgtgtacacacgctctggagaggttaccatatccattgagttgaagaagtctggtttcatgttgtctctacaaatgcttgagttgattacaagacttcaccagtatatattctcacatattcttcggcttgaaaaacctgcactagaatttaaacctacagacgctgattcagcatactgtgttctacctcttaatgttgttaatgactccagcactttggatattgactttaaattcatggaagatattgagaagtctgaagctcgcataggcattcccagtacaaagtatacaaaagaaacaccctttgtttttaaattagaagattaccaagatgccgttatcattccaagatatcgcaattttgatcagcctcatcgattttatgtagctgatgtgtacactgatcttaccccactcagtaaatttccttcccctgagtatgaaacttttgcagaatattataaaacaaagtacaaccttgacctaaccaatctcaaccagccactgctggatgtggaccacacatcttcaagacttaatcttttgacacctcgacatttgaatcagaaggggaaagcgcttcctttaagcagtgctgagaagaggaaagccaaatgggaaagtctgcagaataaacagatactggttccagaactctgtgctatacatccaattccagcatcactgtggagaaaagctgtttgtctccccagcatactttatcgccttcactgccttttgactgcagaggagctaagagcccagactgccagcgatgctggcgtgggagtcagatcacttcctgcggattttagataccctaacttagacttcgggtggaaaaaatctattgacagcaaatctttcatctcaatttctaactcctcttcagctgaaaatgataattactgtaagcacagcacaattgtccctgaaaatgctgcacatcaaggtgctaatagaacctcctctctagaaaatcatgaccaaatgtctgtgaactgcagaacgttgctcagcgagtcccctggtaagctccacgttgaagtttcagcagatcttacagcaattaatggtctttcttacaatcaaaatctcgccaatggcagttatgatttagctaacagagacttttgccaaggaaatcagctaaattactacaagcaggaaatacccgtgcaaccaactacctcatattccattcagaatttatacagttacgagaaccagccccagcccagcgatgaatgtactctcctgagtaataaataccttgatggaaatgctaacaaatctacctcagatggaagtcctgtgatggccgtaatgcctggtacgacagacactattcaagtgctcaagggcaggatggattctgagcagagcccttctattgggtactcctcaaggactcttggccccaatcctggacttattcttcaggctttgactctgtcaaacgctagtgatggatttaacctggagcggcttgaaatgcttggcgactcctttttaaagcatgccatcaccacatatctattttgcacttaccctgatgcgcatgagggccgcctttcatatatgagaagcaaaaaggtcagcaactgtaatctgtatcgccttggaaaaaagaagggactacccagccgcatggtggtgtcaatatttgatccccctgtgaattggcttcctcctggttatgtagtaaatcaagacaaaagcaacacagataaatgggaaaaagatgaaatgacaaaagactgcatgctggcgaatggcaaactggatgaggattacgaggaggaggatgaggaggaggagagcctgatgtggagggctccgaaggaagaggctgactatgaagatgatttcctggagtatgatcaggaacatatcagatttatagataatatgttaatggggtcaggagcttttgtaaagaaaatctctctttctcctttttcaaccactgattctgcatatgaatggaaaatgcccaaaaaatcctccttaggtagtatgccattttcatcagattttgaggattttgactacagctcttgggatgcaatgtgctatctggatcctagcaaagctgttgaagaagatgactttgtggtggggttctggaatccatcagaagaaaactgtggtgttgacacgggaaagcagtccatttcttacgacttgcacactgagcagtgtattgctgacaaaagcatagcggactgtgtggaagccctgctgggctgctatttaaccagctgtggggagagggctgctcagcttttcctctgttcactggggctgaaggtgctcccggtaattaaaaggactgatcgggaaaaggccctgtgccctactcgggagaatttcaacagccaacaaaagaacctttcagtgagctgtgctgctgcttctgtggccagttcacgctcttctgtattgaaagactcggaatatggttgtttgaagattccaccaagatgtatgtttgatcatccagatgcagataaaacactgaatcaccttatatcggggtttgaaaattttgaaaagaaaatcaactacagattcaagaataaggcttaccttctccaggcttttacacatgcctcctaccactacaatactatcactgattgttaccagcgcttagaattcctgggagatgcgattttggactacctcataaccaagcacctttatgaagacccgcggcagcactccccgggggtcctgacagacctgcggtctgccctggtcaacaacaccatctttgcatcgctggctgtaaagtacgactaccacaagtacttcaaagctgtctctcctgagctcttccatgtcattgatgactttgtgcagtttcagcttgagaagaatgaaatgcaaggaatggattctgagcttaggagatctgaggaggatgaagagaaagaagaggatattgaagttccaaaggccatgggggatatttttgagtcgcttgctggtgccatttacatggatagtgggatgtcactggagacagtctggcaggtgtactatcccatgatgcggccactaatagaaaagttttctgcaaatgtaccccgttcccctgtgcgagaattgcttgaaatggaaccagaaactgccaaatttagcccggctgagagaacttacgacgggaaggtcagagtcactgtggaagtagtaggaaaggggaaatttaaaggtgttggtcgaagttacaggattgccaaatctgcagcagcaagaagagccctccgaagcctcaaagctaatcaacctcaggttcccaatagctgaaaccgctttttaaaattcaaaacaagaaacaaaacaaaaaaaattaaggggaaaattatttaaatcggaaaggaagacttaaagttgttagtgagtggaatgaattgaaggcagaatttaaagtttggttgataacaggatagataacagaataaaacatttaacatatgtaaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:23405 -> Molecular function: GO:0003725 [double-stranded RNA binding] evidence: IDA
            GeneID:23405 -> Molecular function: GO:0004525 [ribonuclease III activity] evidence: IDA
            GeneID:23405 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:23405 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
            GeneID:23405 -> Molecular function: GO:0008026 [ATP-dependent helicase activity] evidence: IEA
            GeneID:23405 -> Molecular function: GO:0035198 [miRNA binding] evidence: IEA
            GeneID:23405 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA
            GeneID:23405 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: ISS
            GeneID:23405 -> Biological process: GO:0001525 [angiogenesis] evidence: IEA
            GeneID:23405 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
            GeneID:23405 -> Biological process: GO:0009791 [post-embryonic development] evidence: IEA
            GeneID:23405 -> Biological process: GO:0010070 [zygote asymmetric cell division] evidence: IEA
            GeneID:23405 -> Biological process: GO:0010467 [gene expression] evidence: TAS
            GeneID:23405 -> Biological process: GO:0010626 [negative regulation of Schwann cell proliferation] evidence: ISS
            GeneID:23405 -> Biological process: GO:0014040 [positive regulation of Schwann cell differentiation] evidence: ISS
            GeneID:23405 -> Biological process: GO:0019827 [stem cell maintenance] evidence: IEA
            GeneID:23405 -> Biological process: GO:0021522 [spinal cord motor neuron differentiation] evidence: IEA
            GeneID:23405 -> Biological process: GO:0021675 [nerve development] evidence: ISS
            GeneID:23405 -> Biological process: GO:0021889 [olfactory bulb interneuron differentiation] evidence: IEA
            GeneID:23405 -> Biological process: GO:0021987 [cerebral cortex development] evidence: IEA
            GeneID:23405 -> Biological process: GO:0030324 [lung development] evidence: IEA
            GeneID:23405 -> Biological process: GO:0030422 [production of siRNA involved in RNA interference] evidence: IDA
            GeneID:23405 -> Biological process: GO:0030423 [targeting of mRNA for destruction involved in RNA interference] evidence: IMP
            GeneID:23405 -> Biological process: GO:0031054 [pre-miRNA processing] evidence: IDA
            GeneID:23405 -> Biological process: GO:0031069 [hair follicle morphogenesis] evidence: IEA
            GeneID:23405 -> Biological process: GO:0031643 [positive regulation of myelination] evidence: ISS
            GeneID:23405 -> Biological process: GO:0032290 [peripheral nervous system myelin formation] evidence: ISS
            GeneID:23405 -> Biological process: GO:0035116 [embryonic hindlimb morphogenesis] evidence: IEA
            GeneID:23405 -> Biological process: GO:0035196 [production of miRNAs involved in gene silencing by miRNA] evidence: ISS
            GeneID:23405 -> Biological process: GO:0035264 [multicellular organism growth] evidence: IEA
            GeneID:23405 -> Biological process: GO:0043066 [negative regulation of apoptotic process] evidence: IEA
            GeneID:23405 -> Biological process: GO:0045069 [regulation of viral genome replication] evidence: IEA
            GeneID:23405 -> Biological process: GO:0045664 [regulation of neuron differentiation] evidence: IEA
            GeneID:23405 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IEA
            GeneID:23405 -> Biological process: GO:0048536 [spleen development] evidence: IEA
            GeneID:23405 -> Biological process: GO:0048713 [regulation of oligodendrocyte differentiation] evidence: IEA
            GeneID:23405 -> Biological process: GO:0048754 [branching morphogenesis of an epithelial tube] evidence: IEA
            GeneID:23405 -> Biological process: GO:0048812 [neuron projection morphogenesis] evidence: ISS
            GeneID:23405 -> Biological process: GO:0051225 [spindle assembly] evidence: IEA
            GeneID:23405 -> Biological process: GO:0051607 [defense response to virus] evidence: IEA
            GeneID:23405 -> Biological process: GO:0051726 [regulation of cell cycle] evidence: IEA
            GeneID:23405 -> Biological process: GO:0055013 [cardiac muscle cell development] evidence: IEA
            GeneID:23405 -> Biological process: GO:0060119 [inner ear receptor cell development] evidence: IEA
            GeneID:23405 -> Biological process: GO:0060576 [intestinal epithelial cell development] evidence: IEA
            GeneID:23405 -> Biological process: GO:0070173 [regulation of enamel mineralization] evidence: IEA
            GeneID:23405 -> Biological process: GO:0071335 [hair follicle cell proliferation] evidence: IEA
            GeneID:23405 -> Biological process: GO:2000630 [positive regulation of miRNA metabolic process] evidence: IEA
            GeneID:23405 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:23405 -> Cellular component: GO:0016442 [RNA-induced silencing complex] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
            NP_001258211 -> EC 3.1.26.-

by @meso_cacase at DBCLS
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