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2019-03-22 05:04:42, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001261406            7613 bp    mRNA    linear   PRI 17-JUN-2013
DEFINITION  Homo sapiens multiple PDZ domain protein (MPDZ), transcript variant
            2, mRNA.
ACCESSION   NM_001261406
VERSION     NM_001261406.1  GI:387157891
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7613)
  AUTHORS   Lu,Y., Vitart,V., Burdon,K.P., Khor,C.C., Bykhovskaya,Y.,
            Mirshahi,A., Hewitt,A.W., Koehn,D., Hysi,P.G., Ramdas,W.D.,
            Zeller,T., Vithana,E.N., Cornes,B.K., Tay,W.T., Tai,E.S.,
            Cheng,C.Y., Liu,J., Foo,J.N., Saw,S.M., Thorleifsson,G.,
            Stefansson,K., Dimasi,D.P., Mills,R.A., Mountain,J., Ang,W.,
            Hoehn,R., Verhoeven,V.J., Grus,F., Wolfs,R., Castagne,R.,
            Lackner,K.J., Springelkamp,H., Yang,J., Jonasson,F., Leung,D.Y.,
            Chen,L.J., Tham,C.C., Rudan,I., Vatavuk,Z., Hayward,C., Gibson,J.,
            Cree,A.J., MacLeod,A., Ennis,S., Polasek,O., Campbell,H.,
            Wilson,J.F., Viswanathan,A.C., Fleck,B., Li,X., Siscovick,D.,
            Taylor,K.D., Rotter,J.I., Yazar,S., Ulmer,M., Li,J., Yaspan,B.L.,
            Ozel,A.B., Richards,J.E., Moroi,S.E., Haines,J.L., Kang,J.H.,
            Pasquale,L.R., Allingham,R.R., Ashley-Koch,A., Mitchell,P.,
            Wang,J.J., Wright,A.F., Pennell,C., Spector,T.D., Young,T.L.,
            Klaver,C.C., Martin,N.G., Montgomery,G.W., Anderson,M.G., Aung,T.,
            Willoughby,C.E., Wiggs,J.L., Pang,C.P., Thorsteinsdottir,U.,
            Lotery,A.J., Hammond,C.J., van Duijn,C.M., Hauser,M.A.,
            Rabinowitz,Y.S., Pfeiffer,N., Mackey,D.A., Craig,J.E., Macgregor,S.
            and Wong,T.Y.
  CONSRTM   NEIGHBOR Consortium
  TITLE     Genome-wide association analyses identify multiple loci associated
            with central corneal thickness and keratoconus
  JOURNAL   Nat. Genet. 45 (2), 155-163 (2013)
   PUBMED   23291589
REFERENCE   2  (bases 1 to 7613)
  AUTHORS   Al-Dosari,M.S., Al-Owain,M., Tulbah,M., Kurdi,W., Adly,N.,
            Al-Hemidan,A., Masoodi,T.A., Albash,B. and Alkuraya,F.S.
  TITLE     Mutation in MPDZ causes severe congenital hydrocephalus
  JOURNAL   J. Med. Genet. 50 (1), 54-58 (2013)
   PUBMED   23240096
  REMARK    GeneRIF: Our data strongly support the candidacy of MPDZ as a novel
            congenital hydrocephalus disease gene.
REFERENCE   3  (bases 1 to 7613)
  AUTHORS   Karpyak,V.M., Geske,J.R., Colby,C.L., Mrazek,D.A. and
            Biernacka,J.M.
  TITLE     Genetic variability in the NMDA-dependent AMPA trafficking cascade
            is associated with alcohol dependence
  JOURNAL   Addict Biol 17 (4), 798-806 (2012)
   PUBMED   21762291
  REMARK    GeneRIF: The data indicates potential association between variation
            in mpdz NMDA dependent AMPA trafficking and alcohol dependence.
REFERENCE   4  (bases 1 to 7613)
  AUTHORS   Bailey,S.D., Xie,C., Do,R., Montpetit,A., Diaz,R., Mohan,V.,
            Keavney,B., Yusuf,S., Gerstein,H.C., Engert,J.C. and Anand,S.
  CONSRTM   DREAM investigators
  TITLE     Variation at the NFATC2 locus increases the risk of
            thiazolidinedione-induced edema in the Diabetes REduction
            Assessment with ramipril and rosiglitazone Medication (DREAM) study
  JOURNAL   Diabetes Care 33 (10), 2250-2253 (2010)
   PUBMED   20628086
  REMARK    GeneRIF: Observational study of gene-disease association,
            gene-environment interaction, and pharmacogenomic / toxicogenomic.
            (HuGE Navigator)
REFERENCE   5  (bases 1 to 7613)
  AUTHORS   Talmud,P.J., Drenos,F., Shah,S., Shah,T., Palmen,J., Verzilli,C.,
            Gaunt,T.R., Pallas,J., Lovering,R., Li,K., Casas,J.P., Sofat,R.,
            Kumari,M., Rodriguez,S., Johnson,T., Newhouse,S.J., Dominiczak,A.,
            Samani,N.J., Caulfield,M., Sever,P., Stanton,A., Shields,D.C.,
            Padmanabhan,S., Melander,O., Hastie,C., Delles,C., Ebrahim,S.,
            Marmot,M.G., Smith,G.D., Lawlor,D.A., Munroe,P.B., Day,I.N.,
            Kivimaki,M., Whittaker,J., Humphries,S.E. and Hingorani,A.D.
  CONSRTM   ASCOT investigators; NORDIL investigators; BRIGHT Consortium
  TITLE     Gene-centric association signals for lipids and apolipoproteins
            identified via the HumanCVD BeadChip
  JOURNAL   Am. J. Hum. Genet. 85 (5), 628-642 (2009)
   PUBMED   19913121
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   6  (bases 1 to 7613)
  AUTHORS   Becamel,C., Figge,A., Poliak,S., Dumuis,A., Peles,E., Bockaert,J.,
            Lubbert,H. and Ullmer,C.
  TITLE     Interaction of serotonin 5-hydroxytryptamine type 2C receptors with
            PDZ10 of the multi-PDZ domain protein MUPP1
  JOURNAL   J. Biol. Chem. 276 (16), 12974-12982 (2001)
   PUBMED   11150294
REFERENCE   7  (bases 1 to 7613)
  AUTHORS   Lee,S.S., Glaunsinger,B., Mantovani,F., Banks,L. and Javier,R.T.
  TITLE     Multi-PDZ domain protein MUPP1 is a cellular target for both
            adenovirus E4-ORF1 and high-risk papillomavirus type 18 E6
            oncoproteins
  JOURNAL   J. Virol. 74 (20), 9680-9693 (2000)
   PUBMED   11000240
REFERENCE   8  (bases 1 to 7613)
  AUTHORS   Mancini,A., Koch,A., Stefan,M., Niemann,H. and Tamura,T.
  TITLE     The direct association of the multiple PDZ domain containing
            proteins (MUPP-1) with the human c-Kit C-terminus is regulated by
            tyrosine kinase activity
  JOURNAL   FEBS Lett. 482 (1-2), 54-58 (2000)
   PUBMED   11018522
REFERENCE   9  (bases 1 to 7613)
  AUTHORS   Barritt,D.S., Pearn,M.T., Zisch,A.H., Lee,S.S., Javier,R.T.,
            Pasquale,E.B. and Stallcup,W.B.
  TITLE     The multi-PDZ domain protein MUPP1 is a cytoplasmic ligand for the
            membrane-spanning proteoglycan NG2
  JOURNAL   J. Cell. Biochem. 79 (2), 213-224 (2000)
   PUBMED   10967549
REFERENCE   10 (bases 1 to 7613)
  AUTHORS   Ullmer,C., Schmuck,K., Figge,A. and Lubbert,H.
  TITLE     Cloning and characterization of MUPP1, a novel PDZ domain protein
  JOURNAL   FEBS Lett. 424 (1-2), 63-68 (1998)
   PUBMED   9537516
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL162386.17, BC140793.1, CX782625.1 and BU621500.1.
            
            Transcript Variant: This variant (2) lacks an alternate in-frame
            exon and contains an alternate in-frame exon compared to variant 1.
            The resulting protein (isoform 2) is shorter compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: BC140793.1 [ECO:0000331]
            RNAseq introns       :: mixed/partial sample support ERS025081,
                                    ERS025082 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-165               AL162386.17        49647-49811         c
            166-179             AL162386.17        20606-20619         c
            180-6441            BC140793.1         4-6265
            6442-6866           CX782625.1         302-726
            6867-7613           BU621500.1         1-747               c
FEATURES             Location/Qualifiers
     source          1..7613
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9p23"
     gene            1..7613
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="multiple PDZ domain protein"
                     /db_xref="GeneID:8777"
                     /db_xref="HGNC:7208"
                     /db_xref="MIM:603785"
     exon            1..165
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            166..238
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    208..210
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="upstream in-frame stop codon"
     CDS             223..6336
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="isoform 2 is encoded by transcript variant 2;
                     multi-PDZ domain protein 1"
                     /codon_start=1
                     /product="multiple PDZ domain protein isoform 2"
                     /protein_id="NP_001248335.1"
                     /db_xref="GI:387157892"
                     /db_xref="CCDS:CCDS59120.1"
                     /db_xref="GeneID:8777"
                     /db_xref="HGNC:7208"
                     /db_xref="MIM:603785"
                     /translation="
MLEAIDKNRALHAAERLQTKLRERGDVANEDKLSLLKSVLQSPLFSQILSLQTSVQQLKDQVNIATSATSNIEYAHVPHLSPAVIPTLQNESFLLSPNNGNLEALTGPGIPHINGKPACDEFDQLIKNMAQGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDGRLKETDQILAINGQALDQTITHQQAISILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAASTISAHSNPVHWQHMETIELVNDGSGLGFGIIGGKATGVIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAIEERTAPTALGITLSSSPTSTPELRVDASTQKGEESETFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDADLSPVNASIIKENYEKDEDFLSSTRNTNILPTEEEGYPLLSAEIEEIEDAQKQEAALLTKWQRIMGINYEIVVAHVSKFSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVPPTTQSELDSLDLCDIELTEKPHVDLGEFIGSSETEDPVLAMTDAGQSTEEVQAPLAMWEAGIQHIELEKGSKGLGFSILDYQDPIDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGAPSGTVRIGVAKPLPLSPEEGYVSAKEDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLVDESTFESPYSPENDSIYSTQASILSLHGSSCGDGLNYGSSLPSSPPKDVIENSCDPVLDLHMSLEELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSEVISSAELPSVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGMTVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLIGPDIKITYVPAEHLEEFKISLGQQSGRVMALDIFSSYTGRDIPELPEREEGEGEESELQNTAYSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMVQSIINRPRAPSQSESEPEKAPLCSVPPPPPSAFAEMGSDHTQSSASKISQDVDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGIDPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMAVCPGNAVEPLPSNSENLQNKETEPTVTTSDAAVDLSSFKNVQHLELPKDQGGLGIAISEEDTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAKMTVKLTIHAENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATCPIIPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVAALLKCSLGTVTLEVGRIKAGPFHSERRPSQSSQVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGLRTVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSSSIFQDDLGPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVLS
"
     misc_feature    238..411
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="L27_2; Region: L27_2; pfam09045"
                     /db_xref="CDD:117611"
     misc_feature    637..885
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="PDZ domain found in a variety of Eumetazoan
                     signaling molecules, often in tandem arrangements. May be
                     responsible for specific protein-protein interactions, as
                     most PDZ domains bind C-terminal polypeptides, and binding
                     to internal (non-C-terminal)...; Region: PDZ_signaling;
                     cd00992"
                     /db_xref="CDD:29049"
     misc_feature    order(661..672,676..678,835..840,847..852)
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29049"
     misc_feature    910..912
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (O75970.2); phosphorylation site"
     misc_feature    <1057..1224
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="PDZ domain found in a variety of Eumetazoan
                     signaling molecules, often in tandem arrangements. May be
                     responsible for specific protein-protein interactions, as
                     most PDZ domains bind C-terminal polypeptides, and binding
                     to internal (non-C-terminal)...; Region: PDZ_signaling;
                     cd00992"
                     /db_xref="CDD:29049"
     misc_feature    1345..1599
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="PDZ domain found in a variety of Eumetazoan
                     signaling molecules, often in tandem arrangements. May be
                     responsible for specific protein-protein interactions, as
                     most PDZ domains bind C-terminal polypeptides, and binding
                     to internal (non-C-terminal)...; Region: PDZ_signaling;
                     cd00992"
                     /db_xref="CDD:29049"
     misc_feature    order(1378..1389,1393..1395,1552..1557,1564..1569)
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29049"
     misc_feature    1669..1671
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (O75970.2); phosphorylation site"
     misc_feature    1900..2109
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="PDZ domain found in a variety of Eumetazoan
                     signaling molecules, often in tandem arrangements. May be
                     responsible for specific protein-protein interactions, as
                     most PDZ domains bind C-terminal polypeptides, and binding
                     to internal (non-C-terminal)...; Region: PDZ_signaling;
                     cd00992"
                     /db_xref="CDD:29049"
     misc_feature    order(1912..1923,1927..1929,2065..2070,2077..2082)
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29049"
     misc_feature    2314..2574
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="PDZ domain found in a variety of Eumetazoan
                     signaling molecules, often in tandem arrangements. May be
                     responsible for specific protein-protein interactions, as
                     most PDZ domains bind C-terminal polypeptides, and binding
                     to internal (non-C-terminal)...; Region: PDZ_signaling;
                     cd00992"
                     /db_xref="CDD:29049"
     misc_feature    order(2347..2358,2362..2364,2521..2526,2533..2538)
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29049"
     misc_feature    3238..3450
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="PDZ domain found in a variety of Eumetazoan
                     signaling molecules, often in tandem arrangements. May be
                     responsible for specific protein-protein interactions, as
                     most PDZ domains bind C-terminal polypeptides, and binding
                     to internal (non-C-terminal)...; Region: PDZ_signaling;
                     cd00992"
                     /db_xref="CDD:29049"
     misc_feature    order(3271..3282,3286..3288,3430..3435,3442..3447)
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29049"
     misc_feature    3667..3942
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="PDZ domain found in a variety of Eumetazoan
                     signaling molecules, often in tandem arrangements. May be
                     responsible for specific protein-protein interactions, as
                     most PDZ domains bind C-terminal polypeptides, and binding
                     to internal (non-C-terminal)...; Region: PDZ_signaling;
                     cd00992"
                     /db_xref="CDD:29049"
     misc_feature    order(3703..3714,3718..3720,3892..3897,3904..3909)
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29049"
     misc_feature    4165..4407
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="PDZ domain found in a variety of Eumetazoan
                     signaling molecules, often in tandem arrangements. May be
                     responsible for specific protein-protein interactions, as
                     most PDZ domains bind C-terminal polypeptides, and binding
                     to internal (non-C-terminal)...; Region: PDZ_signaling;
                     cd00992"
                     /db_xref="CDD:29049"
     misc_feature    order(4198..4209,4213..4215,4363..4368,4375..4380)
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29049"
     misc_feature    4564..4803
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="PDZ domain found in a variety of Eumetazoan
                     signaling molecules, often in tandem arrangements. May be
                     responsible for specific protein-protein interactions, as
                     most PDZ domains bind C-terminal polypeptides, and binding
                     to internal (non-C-terminal)...; Region: PDZ_signaling;
                     cd00992"
                     /db_xref="CDD:29049"
     misc_feature    order(4597..4608,4612..4614,4756..4761,4768..4773)
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29049"
     misc_feature    5002..5247
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="PDZ domain found in a variety of Eumetazoan
                     signaling molecules, often in tandem arrangements. May be
                     responsible for specific protein-protein interactions, as
                     most PDZ domains bind C-terminal polypeptides, and binding
                     to internal (non-C-terminal)...; Region: PDZ_signaling;
                     cd00992"
                     /db_xref="CDD:29049"
     misc_feature    order(5035..5046,5050..5052,5200..5205,5212..5217)
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29049"
     misc_feature    5296..5532
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="PDZ domain found in a variety of Eumetazoan
                     signaling molecules, often in tandem arrangements. May be
                     responsible for specific protein-protein interactions, as
                     most PDZ domains bind C-terminal polypeptides, and binding
                     to internal (non-C-terminal)...; Region: PDZ_signaling;
                     cd00992"
                     /db_xref="CDD:29049"
     misc_feature    order(5326..5337,5341..5343,5485..5490,5497..5502)
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29049"
     misc_feature    5701..5958
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="PDZ domain found in a variety of Eumetazoan
                     signaling molecules, often in tandem arrangements. May be
                     responsible for specific protein-protein interactions, as
                     most PDZ domains bind C-terminal polypeptides, and binding
                     to internal (non-C-terminal)...; Region: PDZ_signaling;
                     cd00992"
                     /db_xref="CDD:29049"
     misc_feature    order(5737..5748,5752..5754,5908..5913,5920..5925)
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29049"
     misc_feature    6079..6330
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="PDZ domain found in a variety of Eumetazoan
                     signaling molecules, often in tandem arrangements. May be
                     responsible for specific protein-protein interactions, as
                     most PDZ domains bind C-terminal polypeptides, and binding
                     to internal (non-C-terminal)...; Region: PDZ_signaling;
                     cd00992"
                     /db_xref="CDD:29049"
     misc_feature    order(6109..6120,6124..6126,6280..6285,6292..6297)
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /note="protein binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29049"
     exon            239..405
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            406..615
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            616..755
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            756..969
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     variation       783
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:35440352"
     variation       885
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35476999"
     exon            970..1098
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            1099..1308
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     variation       1263
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:34911705"
     exon            1309..1423
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            1424..1512
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            1513..1696
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            1697..1768
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            1769..1878
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            1879..2025
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            2026..2190
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            2191..2376
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            2377..2586
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            2587..2703
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            2704..2871
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     variation       2802
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34704118"
     variation       2824
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34776397"
     exon            2872..3153
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     variation       3063
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34967070"
     exon            3154..3277
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            3278..3476
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            3477..3581
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            3582..3674
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            3675..3852
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            3853..3963
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            3964..4126
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            4127..4323
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            4324..4415
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            4416..4506
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            4507..4587
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            4588..4680
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            4681..4755
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            4756..4930
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            4931..5076
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            5077..5160
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            5161..5354
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            5355..5502
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            5503..5589
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            5590..5680
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            5681..5724
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            5725..5847
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     variation       5846
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34605667"
     exon            5848..5952
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            5953..6065
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     exon            6066..6189
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     STS             6070..6173
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /standard_name="A005N27"
                     /db_xref="UniSTS:32899"
     STS             6070..6173
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /standard_name="G20352"
                     /db_xref="UniSTS:32898"
     exon            6190..7597
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /inference="alignment:Splign:1.39.8"
     variation       6212
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1802495"
     STS             6251..6896
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /standard_name="MPDZ_8854"
                     /db_xref="UniSTS:467777"
     STS             6486..6791
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /standard_name="SHGC-132458"
                     /db_xref="UniSTS:173909"
     STS             6606..6793
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /standard_name="D9S1039E"
                     /db_xref="UniSTS:54294"
     STS             6669..6793
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /standard_name="SHGC-32204"
                     /db_xref="UniSTS:54293"
     variation       6676
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1057999"
     variation       6965
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:722651"
     variation       7045
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3198580"
     STS             7211..7398
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /standard_name="RH93917"
                     /db_xref="UniSTS:86607"
     STS             7378..7554
                     /gene="MPDZ"
                     /gene_synonym="HYC2; MUPP1"
                     /standard_name="RH47575"
                     /db_xref="UniSTS:38359"
ORIGIN      
cgtgagtgtctgtgcgttttgatccgaagctcctcgccgggtcgttacttcagaagagaagacagtgagcgtgggcgaggcgaggcatccagaggccccggcgacccctgctccccagtcctccgccccctcgcgtcgcggccctgggcgggcgccgcgagccggagttccattttaattgctgttaatcatttcagagaagaacactgaactttgaaaaaaatgttggaagccattgacaaaaatcgggccctgcatgcagcagagcgcttgcaaaccaagctgcgagaacgtggggatgtagcaaatgaagacaaactgagccttctgaagtcagtcctgcagagccctctcttcagtcagattctgagccttcagacttctgtacagcagctgaaagaccaggtaaatattgcaacttcagcaacttcaaatattgaatatgcccacgttcctcatctcagcccagctgtgattcctactctgcaaaatgaatcgtttttattatccccaaacaatgggaatctggaagcacttacaggacctggtattccacacattaatgggaaacctgcttgtgatgaatttgatcagcttatcaaaaatatggcccagggtcgccatgtagaagtttttgagctcctcaaacctccatctggaggccttgggtttagtgttgtgggactaagaagtgaaaacagaggagagctgggaatatttgttcaagagatacaagagggcagtgtggcccatagagatggaagattgaaagaaactgatcaaattcttgctatcaatggacaggctcttgatcagacaattacacatcagcaggctatcagcatcctgcagaaagccaaagatactgtccagctagttattgccagaggctcattgcctcagcttgtcagccccatagtttcccgttctccatctgcagccagcacaatttcagctcactctaatccggttcactggcaacacatggaaacgattgaattggtgaatgatggatctggtttgggatttggcatcataggaggaaaagcaactggtgtgatagtaaaaaccattctgcctggaggagtagctgatcagcatgggcgtttatgcagtggagaccacattctaaagattggtgacacagatctagcaggaatgagcagtgagcaagtagcacaagtccttaggcaatgtggaaatagagttaagttgatgattgcaagaggtgccatagaagaacgtacagcacccactgctttgggcatcaccctctcctcatccccaacttcaacaccagagttgcgggttgatgcttctactcagaaaggtgaagaaagtgagacatttgatgtagaactcactaaaaatgtccaaggattaggaattaccattgctggctacattggagataaaaaattggaaccttcaggaatctttgtaaagagcattacaaaaagcagtgccgttgagcatgatggaagaatccaaattggagaccaaattatagcagtagatggcacaaaccttcagggttttactaatcagcaagcagtagaggtattgcgacatacaggacaaactgtgctcctgacactaatgaggagaggaatgaagcaggaagccgagctcatgtcaagggaagacgtcacaaaagatgcagatttgtctcctgttaatgccagcataatcaaagaaaattatgaaaaagatgaagattttttatcttcgacgagaaacaccaacatattaccaactgaagaagaagggtatccattactgtcagctgagatagaagaaatagaagatgcacaaaaacaagaagctgctctgctgacaaaatggcaaaggattatgggaattaactatgaaatagtggtggcccatgtgagcaagtttagtgagaacagtggattggggataagcctggaagcgacagtgggacatcattttatccgatctgttctaccagagggtcctgttggacacagcgggaagctcttcagtggagacgagctattggaagtaaatggcataactttacttggggaaaatcaccaagatgtggtgaatatcttaaaagaactgcctatagaagtgacaatggtgtgctgtcgtcgaactgtgccacccaccacccaatcagaattggatagcctggacttatgtgatattgagctaacagaaaagcctcacgtagatctaggtgagttcatcgggtcatcagagacagaggatccagtgctggcgatgactgatgcgggtcagagtacagaagaggttcaagcacctttggccatgtgggaggctggcattcagcacatagagctggagaaagggagcaaaggacttggttttagcattttagattatcaggatccaattgatccagcaagcactgtgattataattcgttctttggtgcctggcggcattgctgaaaaggatggacgacttcttcctggtgaccgactcatgtttgtaaacgatgttaacttggaaaacagcagtcttgaggaagctgtagaagcactgaagggagcaccgtcagggactgtgagaataggagttgctaagcctttacccctttcaccagaagaaggttatgtttctgctaaggaggattcctttctctacccaccacactcctgtgaggaagcagggctggctgacaaacccctcttcagggctgacttggctctggtgggcacaaatgatgctgacttagtagatgaatccacatttgagtctccatactctcctgaaaatgacagcatctactctactcaagcctctattttatctcttcatggcagttcttgtggtgatggcctgaactatggttcttcccttccatcatctcctcctaaggatgttattgaaaattcttgtgatccagtacttgatctgcatatgtctctggaggaactatatacccagaatctcctgcaaagacaggatgagaatacaccttcggtggacataagtatggggcctgcttctggctttactataaatgactacacacctgcaaatgctattgaacaacaatatgaatgtgaaaacacaatagtgtggactgaatctcatttaccaagtgaagttatatcaagtgcagaacttccttctgtgctacccgattcagctggaaagggctctgagtacctgcttgaacagagctccctggcctgtaatgctgagtgtgtcatgcttcaaaatgtatctaaagaatcttttgaaaggactattaatatagcaaaaggcaattctagcctaggaatgacagttagtgctaataaagatggcttggggatgatcgttcgaagcattattcatggaggtgccattagtcgagatggccggattgccattggggactgcatcttgtccattaatgaagagtctaccatcagtgtaaccaatgcccaggcacgagctatgttgagaagacattctctcattggccctgacataaaaattacttatgtgcctgcagaacatttggaagagttcaaaataagcttgggacaacaatctggaagagtaatggcactggatattttttcttcatacactggcagagacattccagaattaccagagcgagaagagggagagggtgaagaaagcgaacttcaaaacacagcatatagcaattggaatcagcccaggcgggtggaactctggagagaaccaagcaaatccttaggcatcagcattgttggtggacgagggatggggagtcggctaagcaatggagaagtgatgaggggcattttcatcaaacatgttctggaagatagtccagctggcaaaaatggaaccttgaaacctggagatagaatcgtagaggtggatggaatggacctcagagatgcaagccatgaacaagctgtggaagccattcggaaagcaggcaaccctgtagtctttatggtacagagcattataaacagaccaagggcacccagtcagtcagagtcagagccagagaaggctccattgtgcagtgtgcccccaccccctccttcagcctttgccgaaatgggtagtgatcacacacagtcatctgcaagcaaaatctcacaagatgtggacaaagaggatgagtttggttacagctggaaaaatatcagagagcgttatggaaccctaacaggcgagctgcatatgattgaactggagaaaggtcatagtggtttgggcctaagtcttgctgggaacaaagaccgatccaggatgagtgtcttcatagtggggattgatccaaatggagctgcaggaaaagatggtcgattgcaaattgcagatgagcttctagagatcaatggtcagattttatatggaagaagtcatcagaatgcctcatcaatcattaaatgtgccccttctaaagtgaaaataatttttatcagaaataaagatgcagtgaatcagatggccgtatgtcctggaaatgcagtagaacctttgccttctaactcagaaaatcttcaaaataaggagacagagccaactgttactacttctgatgcagctgtggacctcagttcatttaaaaatgtgcaacatctggagcttcccaaggatcaggggggtttgggtattgctatcagcgaagaagatacactcagtggagtcatcataaagagcttaacagagcatggggtagcagccacggatggacgactcaaagtcggagatcagatactggctgtagatgatgaaattgttgttggttaccctattgaaaagtttattagccttctgaagacagcaaagatgacagtaaaacttaccatccatgctgagaatccagattcccaggctgttccttcagcagctggtgcagccagtggagaaaaaaagaacagctcccagtctctgatggtcccacagtctggctccccagaaccggagtccatccgaaatacaagcagatcatcaacaccagcaatttttgcttctgatcctgcaacctgccccattatccctggctgcgaaacaaccatcgagatttccaaagggcgaacagggctgggcctgagcatcgttgggggttcagacacgctgctgggtgccattattatccatgaagtttatgaagaaggagcagcatgtaaagatggaagactctgggctggagatcagatcttagaggtgaatggaattgacttgagaaaggccacacatgatgaagcaatcaatgtcctgagacagacgccacagagagtgcgcctgacactctacagagatgaggccccatacaaagaggaggaagtgtgtgacaccctcactattgagctgcagaagaagccgggaaaaggcctaggattaagtattgttggtaaaagaaacgatactggagtatttgtgtcagacattgtcaaaggaggaattgcagatgccgatggaagactgatgcagggagaccagatattaatggtgaatggggaagacgttcgtaatgccacccaagaagcggttgccgctttgctaaagtgttccctaggcacagtaaccttggaagttggaagaatcaaagctggtccattccattcagagaggaggccatctcaaagcagccaggtgagtgaaggcagcctgtcatctttcacttttccactctctggatccagtacatctgagtcactggaaagtagctcaaagaagaatgcattggcatctgaaatacagggattaagaacagtcgaaatgaaaaagggccctactgactcactgggaatcagcatcgctggaggagtaggcagcccacttggtgatgtgcctatatttattgcaatgatgcacccaactggagttgcagcacagacccaaaaactcagagttggggataggattgtcaccatctgtggcacatccactgagggcatgactcacacccaagcagttaacctactgaaaaatgcatctggctccattgaaatgcaggtggttgctggaggagacgtgagtgtggtcacaggtcatcagcaggagcctgcaagttccagtctttctttcactgggctgacgtcaagcagtatatttcaggatgatttaggacctcctcaatgtaagtctattacactagagcgaggaccagatggcttaggcttcagtatagttggaggatatggcagccctcatggagacttacccatttatgttaaaacagtgtttgcaaagggagcagcctctgaagacggacgtctgaaaaggggcgatcagatcattgctgtcaatgggcagagtctagaaggagtcacccatgaagaagctgttgccatccttaaacggacaaaaggcactgtcactttgatggttctctcttgaattggctgccagaattgaaccaacccaacccctagctcacctcctactgtaaagagaatgcactggtcctgacaatttttatgctgtgttcagccgggtcttcaaaactgtaggggggaaataacacttaagtttctttttctcatctagaaatgctttccttactgacaacctaacatcatttttcttttcttcttgcattttgtgaacttaaagagaaggaatatttgtgtaggtgaatctcgtttttatttgtggagatatctaatgttttgtagtcacatgggcaagaattattacatgctaagctggttagtataaagaaagataattctaaagctaaccaaagaaaatggcttcagtaaattaggatgaaaaatgaaaatataaaataaagaagaaaatctcggggagtttaaaaaaaatgcctcaatttggcaatctacctcctctccccaccccaaactaaaaaaagaaaaaaaggttttctaatgaaaatctttaaaaatactgtcagtattttaaaattttcaacagtattataaaaacattgcatctccccacctctaatatgcatatatatttttcctgctaaaattggtttctacaattgagtaaatggcaaatacatgaagcaatgtccctaaattttataaagaaattatatttaatgcacatttcaattttcattcttatttttgaccttttgtaaaatattttcatgttgctataagtaaatgatgatgccaccccatgttgactatggtttttctagaaagcaactatgctgctaaccatagaggaacatagaagggttccagaatctttagtgctggttttaacaaccgatgcaacattaaaaatgtgttagtgtgctgtgcaattggttttcaattcatattaatcttaatgacagagaacaatgtgttactaattattttggttgtatgccattagtaaattgatagaaaaattaaggggattaacataacttcatttcattgccttatattaacatcttataatacaatagtttaagactaagggaaacagatggagctgtttattgagacaactggtgaggaattatcatgtgttcattcccattttagagcgtgaaactcctacattagaatatataaagtcactttaaatatctatatttgtaacagaagtagtgtacagatattttattacagcatttttgtgtaaatgcagaattaaagtgaataaataagaattttcagtggtgcacaaataaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:8777 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:8777 -> Molecular function: GO:0008022 [protein C-terminus binding] evidence: IPI
            GeneID:8777 -> Biological process: GO:0007155 [cell adhesion] evidence: IEA
            GeneID:8777 -> Biological process: GO:0019048 [modulation by virus of host morphology or physiology] evidence: IEA
            GeneID:8777 -> Biological process: GO:0042552 [myelination] evidence: IEA
            GeneID:8777 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:8777 -> Cellular component: GO:0005923 [tight junction] evidence: IEA
            GeneID:8777 -> Cellular component: GO:0014069 [postsynaptic density] evidence: IEA
            GeneID:8777 -> Cellular component: GO:0016324 [apical plasma membrane] evidence: IEA
            GeneID:8777 -> Cellular component: GO:0016327 [apicolateral plasma membrane] evidence: IDA
            GeneID:8777 -> Cellular component: GO:0030425 [dendrite] evidence: IEA
            GeneID:8777 -> Cellular component: GO:0031410 [cytoplasmic vesicle] evidence: IEA
            GeneID:8777 -> Cellular component: GO:0043220 [Schmidt-Lanterman incisure] evidence: IEA
            GeneID:8777 -> Cellular component: GO:0045211 [postsynaptic membrane] evidence: IEA

by @meso_cacase at DBCLS
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