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2024-04-20 07:35:38, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001256858 1479 bp mRNA linear PRI 18-APR-2013
DEFINITION Homo sapiens ring finger protein 34, E3 ubiquitin protein ligase
(RNF34), transcript variant 3, mRNA.
ACCESSION NM_001256858
VERSION NM_001256858.1 GI:378925641
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1479)
AUTHORS Lin,M.L., Lu,Y.C., Su,H.L., Lin,H.T., Lee,C.C., Kang,S.E.,
Lai,T.C., Chung,J.G. and Chen,S.S.
TITLE Destabilization of CARP mRNAs by aloe-emodin contributes to
caspase-8-mediated p53-independent apoptosis of human carcinoma
cells
JOURNAL J. Cell. Biochem. 112 (4), 1176-1191 (2011)
PUBMED 21308745
REMARK GeneRIF: Data indicate AE induces caspase-8-mediated activation of
mitochondrial death pathways by decreasing the stability of CARP
mRNAs in a p53-independent manner.
REFERENCE 2 (bases 1 to 1479)
AUTHORS Erlbruch,A., Hung,C.W., Seidler,J., Borrmann,K., Gesellchen,F.,
Konig,N., Kubler,D., Herberg,F.W., Lehmann,W.D. and Bossemeyer,D.
TITLE Uncoupling of bait-protein expression from the prey protein
environment adds versatility for cell and tissue interaction
proteomics and reveals a complex of CARP-1 and the PKA Cbeta1
subunit
JOURNAL Proteomics 10 (16), 2890-2900 (2010)
PUBMED 20564261
REMARK GeneRIF: The previously unknown small molecule inhibitor-dependent
interaction of Cbeta1 with the cell cycle and apoptosis regulatory
protein-1 was verified.
REFERENCE 3 (bases 1 to 1479)
AUTHORS Yang,W., Dicker,D.T., Chen,J. and El-Deiry,W.S.
TITLE CARPs enhance p53 turnover by degrading 14-3-3sigma and stabilizing
MDM2
JOURNAL Cell Cycle 7 (5), 670-682 (2008)
PUBMED 18382127
REMARK GeneRIF: CARPs together with MDM2 enhance p53 degradation, thereby
inhibiting p53-mediated cell death.
REFERENCE 4 (bases 1 to 1479)
AUTHORS Yang,W., Rozan,L.M., McDonald,E.R. III, Navaraj,A., Liu,J.J.,
Matthew,E.M., Wang,W., Dicker,D.T. and El-Deiry,W.S.
TITLE CARPs are ubiquitin ligases that promote MDM2-independent p53 and
phospho-p53ser20 degradation
JOURNAL J. Biol. Chem. 282 (5), 3273-3281 (2007)
PUBMED 17121812
REFERENCE 5 (bases 1 to 1479)
AUTHORS Konishi,T., Sasaki,S., Watanabe,T., Kitayama,J. and Nagawa,H.
TITLE Overexpression of hRFI (human ring finger homologous to inhibitor
of apoptosis protein type) inhibits death receptor-mediated
apoptosis in colorectal cancer cells
JOURNAL Mol. Cancer Ther. 4 (5), 743-750 (2005)
PUBMED 15897238
REFERENCE 6 (bases 1 to 1479)
AUTHORS Sasaki,S., Watanabe,T., Konishi,T., Kitayama,J. and Nagawa,H.
TITLE Effects of expression of hRFI on adenoma formation and tumor
progression in colorectal adenoma-carcinoma sequence
JOURNAL J. Exp. Clin. Cancer Res. 23 (3), 507-512 (2004)
PUBMED 15595643
REMARK GeneRIF: hRFI may act as an oncogenic molecule affecting the
apoptotic pathway
REFERENCE 7 (bases 1 to 1479)
AUTHORS McDonald,E.R. III and El-Deiry,W.S.
TITLE Suppression of caspase-8- and -10-associated RING proteins results
in sensitization to death ligands and inhibition of tumor cell
growth
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 101 (16), 6170-6175 (2004)
PUBMED 15069192
REFERENCE 8 (bases 1 to 1479)
AUTHORS Sasaki,S., Nakamura,T., Arakawa,H., Mori,M., Watanabe,T., Nagawa,H.
and Croce,C.M.
TITLE Isolation and characterization of a novel gene, hRFI,
preferentially expressed in esophageal cancer
JOURNAL Oncogene 21 (32), 5024-5030 (2002)
PUBMED 12118383
REMARK GeneRIF: a novel gene, hRFI, preferentially expressed in esophageal
cancer (hRFI)
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DB242808.1, BI559962.1 and
AK025439.1.
Summary: The protein encoded by this gene contains a RINF finger, a
motif known to be involved in protein-protein and protein-DNA
interactions. This protein interacts with DNAJA3/hTid-1, which is a
DnaJ protein reported to function as a modulator of apoptosis.
Overexpression of this gene in Hela cells was shown to confer the
resistance to TNF-alpha induced apoptosis, suggesting an
anti-apoptotic function of this protein. This protein can be
cleaved by caspase-3 during the induction of apoptosis. This
protein also targets p53 and phospho-p53 for degradation.
Alternatively splicing results in multiple transcript variants
encoding distinct isoforms. [provided by RefSeq, Feb 2012].
Transcript Variant: This variant (3) has multiple differences in
the 5' coding region which results in the use of an alternate
translational start codon, compared to variant 1. The resulting
isoform (3) has a shorter N-terminus, compared to variant 1.
##Evidence-Data-START##
Transcript exon combination :: BI559962.1, CX757662.1 [ECO:0000332]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-31 DB242808.1 1-31
32-708 BI559962.1 7-683
709-1479 AK025439.1 1250-2020
FEATURES Location/Qualifiers
source 1..1479
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q24.31"
gene 1..1479
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/note="ring finger protein 34, E3 ubiquitin protein
ligase"
/db_xref="GeneID:80196"
/db_xref="HGNC:17297"
/db_xref="MIM:608299"
exon 1..136
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/inference="alignment:Splign:1.39.8"
misc_feature 35..37
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/note="upstream in-frame stop codon"
variation 37
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:374975607"
variation 39..41
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace=""
/replace="cac"
/db_xref="dbSNP:200012941"
variation 56
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:61733229"
variation 61
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="g"
/db_xref="dbSNP:182031296"
variation 76
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="g"
/db_xref="dbSNP:371429893"
variation 78
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:375539157"
variation 82
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="t"
/db_xref="dbSNP:368256317"
variation 121
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:199515654"
CDS 131..673
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/EC_number="6.3.2.-"
/note="isoform 3 is encoded by transcript variant 3; RING
finger protein RIFF; FYVE-RING finger protein MOMO;
caspases-8 and -10-associated RING finger protein 1; E3
ubiquitin-protein ligase RNF34; caspase regulator CARP1;
human RING finger homologous to inhibitor of apoptosis
protein"
/codon_start=1
/product="E3 ubiquitin-protein ligase RNF34 isoform 3"
/protein_id="NP_001243787.1"
/db_xref="GI:378925642"
/db_xref="GeneID:80196"
/db_xref="HGNC:17297"
/db_xref="MIM:608299"
/translation="
MKGELMDGDQTSRSGVPAQVQSEITSANTEDDDDDDDEDDDDEEENAEDRNPGLSKERVRASLSDLSSLDDVEGMSVRQLKEILARNFVNYSGCCEKWELVEKVNRLYKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVFKS
"
misc_feature 515..649
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/note="Zinc finger, C3HC4 type (RING finger); Region:
zf-C3HC4_3; pfam13920"
/db_xref="CDD:206091"
misc_feature 515..637
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/note="Zinc finger, C3HC4 type (RING finger); Region:
zf-C3HC4_2; pfam13923"
/db_xref="CDD:206094"
exon 137..187
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/inference="alignment:Splign:1.39.8"
variation 170
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="t"
/db_xref="dbSNP:150408238"
exon 188..280
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/inference="alignment:Splign:1.39.8"
variation 193
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:138199363"
variation 221..223
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace=""
/replace="gat"
/db_xref="dbSNP:72059744"
variation 223..225
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace=""
/replace="tga"
/db_xref="dbSNP:370767127"
variation 223
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="c"
/db_xref="dbSNP:185279212"
variation 229
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="g"
/db_xref="dbSNP:190921881"
variation 229
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace=""
/replace="tga"
/db_xref="dbSNP:77544919"
variation 232
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="t"
/db_xref="dbSNP:202132357"
variation 235
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="t"
/db_xref="dbSNP:377017432"
variation 256
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="t"
/db_xref="dbSNP:61739898"
variation 259
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="t"
/db_xref="dbSNP:61751317"
variation 269
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="g"
/replace="t"
/db_xref="dbSNP:368005152"
variation 278
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="c"
/db_xref="dbSNP:184904177"
exon 281..482
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/inference="alignment:Splign:1.39.8"
variation 287
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:143285387"
variation 306
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="g"
/replace="t"
/db_xref="dbSNP:139288912"
variation 368
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="g"
/db_xref="dbSNP:34812514"
variation 369
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace=""
/replace="g"
/replace="t"
/db_xref="dbSNP:34201718"
variation 388
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:375929001"
variation 399
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:201019913"
variation 414
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="t"
/db_xref="dbSNP:183189219"
variation 416
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="g"
/replace="t"
/db_xref="dbSNP:186249284"
variation 434
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:1110337"
variation 438
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:113432721"
variation 447
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:373568534"
variation 448
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="g"
/replace="t"
/db_xref="dbSNP:143217753"
exon 483..1449
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/inference="alignment:Splign:1.39.8"
variation 487
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="t"
/db_xref="dbSNP:200513045"
variation 492
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:369744966"
variation 519..520
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace=""
/replace="cccccc"
/replace="gaaaccccc"
/db_xref="dbSNP:139170044"
variation 547
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="t"
/db_xref="dbSNP:373171102"
variation 554
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:144819272"
variation 601
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="t"
/db_xref="dbSNP:376706808"
variation 609
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:61754471"
variation 632
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="t"
/db_xref="dbSNP:370848382"
variation 647
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="t"
/db_xref="dbSNP:372856839"
variation 658
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="t"
/db_xref="dbSNP:377078507"
variation 659
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:370330071"
variation 669
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="t"
/db_xref="dbSNP:200273600"
variation 692
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:147553178"
variation 712
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:374677569"
variation 718
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="c"
/db_xref="dbSNP:28557279"
variation 719
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:111571472"
variation 728
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:372267828"
variation 747
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:77286564"
variation 881
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="t"
/db_xref="dbSNP:377270647"
variation 923
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="g"
/replace="t"
/db_xref="dbSNP:183521191"
variation 941
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:140213777"
variation 1095
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="c"
/db_xref="dbSNP:3751132"
variation 1139
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:151100805"
STS 1207..1418
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/standard_name="NIB1331"
/db_xref="UniSTS:58859"
STS 1274..1424
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/standard_name="D12S1398"
/db_xref="UniSTS:32605"
STS 1281..1409
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/standard_name="G62101"
/db_xref="UniSTS:139128"
variation 1284
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="t"
/db_xref="dbSNP:11545005"
variation 1365
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="a"
/replace="g"
/db_xref="dbSNP:8462"
variation 1402
/gene="RNF34"
/gene_synonym="CARP-1; CARP1; hRFI; RFI; RIF; RIFF"
/replace="c"
/replace="t"
/db_xref="dbSNP:141042508"
ORIGIN
acgtccggacgctcggtcgcctcccggggcgcggtaatcaccgcccagagggaaggaggtcggcagtgtgaggagctgctatggtgctgagtttcctggtagagccggccgagctgaggcggtcgcggccatgaagggagagcttatggatggagaccaaacatccagatctggagtgccggcacaggtacaaagtgaaatcacttcagcaaacacagaagatgatgatgacgacgatgatgaggatgatgatgatgaagaagaaaacgcagaggatcggaaccccgggctctccaaggagagagtgagagcttcactgtctgacttgtcaagccttgatgatgtggaaggaatgagcgtgcgccagctgaaggaaattctggctcggaattttgtcaactattctggctgttgtgaaaaatgggaactggtagagaaagtaaaccggttatacaaagagaatgaagaaaaccaaaagtcctatggcgagcggctgcagctgcaggatgaggaagacgacagcctgtgtcgcatctgcatggatgccgtcatcgactgtgtcctactggagtgtgggcacatggttacctgcaccaagtgcggcaagcgcatgagtgagtgtcccatctgccggcagtatgtggtgcgagccgtgcacgtgttcaagtcctgaaacaggctcccctcaccaggacagtcacccccaaacttgacccccaacatttcaatgcacagaagggactggaaagttatgttcaaaggctgaagctattttaaaacattattttgactactaagtggggacagaaagatccatcctgagttgtggaaacattggtccatgccgtgagcctgtctgcctgtggacacgtgagcttcccgggctcagctgggctttatcacacatcccgtgaacactcattgaagtcagcctgtttgcgccatgtgggcatcagccactgctgtcttgggaggacacttatcctgttctcttatttccccttcatcctatttttaacttaaactgctcagatgtttgaaacttctgtcctctttggatgagatcagtgtccacaagtggccgacatggaacatgctgagcagtggctcctctgaatgttcactttattagtcatgtatattttaaatgctaacatttgatgaatgtaagtttccacattgttgctgtttctgcatttaaacataattgggaacaactgacattctctagtcgactgccagggccttagactccacatgtccatttttgttcaggtatagctttttatagcaagggctgcatctagcttcttttattagaagtgtgtgtgctaaattccttattaatgtgtaatcagtttacattgttttgtatagtgaaggtgtattttcagtgctacccgctagctgattttaactttaggaataaaattagttttaaaagcttttaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:80196 -> Molecular function: GO:0004842 [ubiquitin-protein ligase activity] evidence: IEA
GeneID:80196 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA
GeneID:80196 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:80196 -> Cellular component: GO:0012505 [endomembrane system] evidence: IEA
GeneID:80196 -> Cellular component: GO:0016020 [membrane] evidence: IEA
GeneID:80196 -> Cellular component: GO:0016607 [nuclear speck] evidence: IEA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_001243787 -> EC 6.3.2.-
by
@meso_cacase at
DBCLS
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