LOCUS       NM_001244584            2747 bp    mRNA    linear   PRI 08-JUL-2013
DEFINITION  Homo sapiens C7orf55-LUC7L2 readthrough (C7orf55-LUC7L2), mRNA.
ACCESSION   NM_001244584
VERSION     NM_001244584.2  GI:397174785
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2747)
  AUTHORS   Prakash,T., Sharma,V.K., Adati,N., Ozawa,R., Kumar,N., Nishida,Y.,
            Fujikake,T., Takeda,T. and Taylor,T.D.
  TITLE     Expression of conjoined genes: another mechanism for gene
            regulation in eukaryotes
  JOURNAL   PLoS ONE 5 (10), E13284 (2010)
   PUBMED   20967262
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC083880.5, AK297642.1 and AC083883.6.
            On Jul 24, 2012 this sequence version replaced gi:347446675.
            
            Summary: This locus represents naturally occurring readthrough
            transcription between the neighboring C7orf55 (chromosome 7 open
            reading frame 55) and LUC7L2 (LUC7-like 2) genes on chromosome 7.
            The readthrough transcript encodes a fusion protein that shares
            sequence identity with each individual gene product. [provided by
            RefSeq, Jul 2012].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK297642.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025084, ERS025088 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            readthrough transcript :: includes exons from GeneID 51631, 154791
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-228               AC083880.5         7322-7549
            229-1889            AK297642.1         1-1661
            1890-2747           AC083883.6         52303-53160
FEATURES             Location/Qualifiers
     source          1..2747
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q"
     gene            1..2747
                     /gene="C7orf55-LUC7L2"
                     /note="C7orf55-LUC7L2 readthrough"
                     /db_xref="GeneID:100996928"
                     /db_xref="HGNC:44671"
     exon            1..391
                     /gene="C7orf55-LUC7L2"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    143..145
                     /gene="C7orf55-LUC7L2"
                     /note="upstream in-frame stop codon"
     variation       167
                     /gene="C7orf55-LUC7L2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:6960314"
     variation       202
                     /gene="C7orf55-LUC7L2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:114009688"
     variation       222
                     /gene="C7orf55-LUC7L2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372818202"
     CDS             254..1630
                     /gene="C7orf55-LUC7L2"
                     /codon_start=1
                     /product="C7orf55-LUC7L2 protein"
                     /protein_id="NP_001231513.1"
                     /db_xref="GI:347446676"
                     /db_xref="CCDS:CCDS59084.1"
                     /db_xref="GeneID:100996928"
                     /db_xref="HGNC:44671"
                     /translation="

MAALGSPSHTFRGLLRELRYLSAATGRPYRDTAAYRYLVKAFRAHRVTSEKLCRAQHELHFQAATYLCLLRSIRKHVALHQEFHGKGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI

"
     misc_feature    278..556
                     /gene="C7orf55-LUC7L2"
                     /note="Complex1_LYR-like; Region: Complex1_LYR_2;
                     pfam13233"
                     /db_xref="CDD:205414"
     misc_feature    512..1150
                     /gene="C7orf55-LUC7L2"
                     /note="LUC7 N_terminus; Region: LUC7; pfam03194"
                     /db_xref="CDD:112027"
     misc_feature    518..1135
                     /gene="C7orf55-LUC7L2"
                     /note="U1 snRNP component, mediates U1 snRNP association
                     with cap-binding complex [RNA processing and
                     modification]; Region: LUC7; COG5200"
                     /db_xref="CDD:34799"
     exon            392..512
                     /gene="C7orf55-LUC7L2"
                     /inference="alignment:Splign:1.39.8"
     exon            513..607
                     /gene="C7orf55-LUC7L2"
                     /inference="alignment:Splign:1.39.8"
     exon            608..706
                     /gene="C7orf55-LUC7L2"
                     /inference="alignment:Splign:1.39.8"
     exon            707..817
                     /gene="C7orf55-LUC7L2"
                     /inference="alignment:Splign:1.39.8"
     exon            818..961
                     /gene="C7orf55-LUC7L2"
                     /inference="alignment:Splign:1.39.8"
     exon            962..1138
                     /gene="C7orf55-LUC7L2"
                     /inference="alignment:Splign:1.39.8"
     exon            1139..1230
                     /gene="C7orf55-LUC7L2"
                     /inference="alignment:Splign:1.39.8"
     exon            1231..1260
                     /gene="C7orf55-LUC7L2"
                     /inference="alignment:Splign:1.39.8"
     exon            1261..1452
                     /gene="C7orf55-LUC7L2"
                     /inference="alignment:Splign:1.39.8"
     exon            1453..2747
                     /gene="C7orf55-LUC7L2"
                     /inference="alignment:Splign:1.39.8"
     STS             2604..2728
                     /gene="C7orf55-LUC7L2"
                     /standard_name="SGC30686"
                     /db_xref="UniSTS:83282"
ORIGIN      

caaacccttgttctgggttagaggtcctggtaccttcagttaacagtcgggtttcgtttgattttgttacggcgcccctgggccttcgattaataaggttcggtcaacggacaagtgagcggttccactgctcgtcagtcgatagggggagtcggtagtctgtccgaccgtaccattaggcgcctgggccggaggaggggttttcagggtcgtaggacgccgttgggcaccacgctcggagaaggacaggacaatggcggccttagggtccccgtcgcacacttttcgaggacttctgcgggagttgcgctacctgagcgcggccaccggccgaccctatcgcgacaccgcggcctatcggtaccttgtgaaggctttccgtgcacatcgggtcaccagtgaaaagttgtgcagagcccaacatgagcttcatttccaagctgccacctatctctgcctcctgcgtagcatccggaaacatgtggccctacatcaggaatttcatggcaagggagatacaactcgtcaacgaatcaaattcagtgatgacagagtatgcaagagtcaccttctcaactgttgtcctcatgatgtcctttctggaactagaatggatcttggagaatgtctgaaagtccatgacctggctttaagagcggattatgaaattgcatccaaagaacaagattttttctttgaacttgatgccatggatcatctgcagtcattcattgcagattgtgatcgtagaacagaagtggccaagaaaagattagcagaaactcaagaagagattagtgctgaagtagcagcaaaggcagaacgtgttcatgagttaaatgaagaaattggtaaattgttagccaaggtggaacaactaggagctgaagggaatgtggaggaatcccagaaagtaatggatgaagtagagaaagcacgggcaaagaaaagagaagcagaggaagtttatcggaattctatgccagcttccagttttcagcagcagaaacttcgagtctgtgaagtctgctctgcctatttaggacttcatgataatgacagacgactggctgatcattttgggggtaaactgcacctgggatttattgaaataagagagaagcttgaagaattaaagagagtcgtagctgagaagcaggagaaaagaaaccaggaacggctgaaacgaagagaagagagagagagagaagaaagggagaagctgaggaggtcccgatcacacagcaagaatccaaaaagatccaggtccagagagcatcgcagacatcgatctcgctccatgtcacgtgaacgcaagaggagaactcgatccaaatctcgggagaaacgccatcgccacaggtcccgctccagcagccgtagccgcagccgtagccaccagagaagtcggcacagttctagagataggagcagagaacgatccaagaggagatcctcaaaagaaagattcagagaccaagacttagcatcatgtgacagagacaggagttcaagagacagatcacctcgtgacagagatcggaaagataagaagcggtcctatgagagtgctaatggcagatcagaagacaggaggagctctgaagagcgcgaagcaggggagatctaactagctgtgtacatttcttcagtccttaagcttcctacggagttacgtactattgtttagttcacagctgttcagggtgacagtgagcagatccagacaccagatccagctaggctagatgtacagtatctaacttgatctgaactgaacctgttttccttgatgatgcctaaaactacatccatagtttctggtgaacctgtaatacagttctgaaagtacagttttatataataagatgctgatctctttattctttcaagtaagagtgctagtgaacaaattgtgttacttgccttgggattttttgaacgtttgtaaaatgctgtcttcctagtccaaacagctgcagctttgggcatttttctttttaattattcttcctctgactttgtatcccttaatacctacactctccaattgtaagagaaagggggcagggaagcaatatagcttccattctaaggctgtattcccgttatgaattactagctgattacagttcagagcattgatcctggaatgtgtgctggagaaatttaaaatactggggttttttgtttaatggtgcctatttagagttggaagttgaacagctgttgcattacatacttttgcttttttattgaaattttgaaatcaaacgtcttgatttttctgttctgttgaattgctatgttcaggatgttctagggggtgggggcagggactcttttcgtaataagcacttgttttattttgtgtgtgtggagtataaaggctacacccttattgtaaaaaaataataataataaaatgaaagaaacaatcaccaccaccattattaaactgtaacttgtctagtaaattgtcactagaactatttgctgtgggcatttcctctattctgttacgtcattaacagtgccttactgtgcaaggcaccaaaggacataaatacgtacttgcaaagattccagatgagctgttcatgtgggccccttgctgactatattccagccacttcagggttgtttgtaatgaccgttatagagaagggctcgacctgcagaagaaactggggtgtttttattctcattcaacaaacccaaataaaaacagtatatgtaaccaacat

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