Home |
Help |
Advanced search
2024-04-26 23:55:29, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001206480 5335 bp mRNA linear PRI 29-JUN-2013
DEFINITION Homo sapiens engulfment and cell motility 1 (ELMO1), transcript
variant 4, mRNA.
ACCESSION NM_001206480
VERSION NM_001206480.1 GI:330688433
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5335)
AUTHORS Dulak,A.M., Stojanov,P., Peng,S., Lawrence,M.S., Fox,C.,
Stewart,C., Bandla,S., Imamura,Y., Schumacher,S.E., Shefler,E.,
McKenna,A., Carter,S.L., Cibulskis,K., Sivachenko,A., Saksena,G.,
Voet,D., Ramos,A.H., Auclair,D., Thompson,K., Sougnez,C.,
Onofrio,R.C., Guiducci,C., Beroukhim,R., Zhou,Z., Lin,L., Lin,J.,
Reddy,R., Chang,A., Landrenau,R., Pennathur,A., Ogino,S.,
Luketich,J.D., Golub,T.R., Gabriel,S.B., Lander,E.S., Beer,D.G.,
Godfrey,T.E., Getz,G. and Bass,A.J.
TITLE Exome and whole-genome sequencing of esophageal adenocarcinoma
identifies recurrent driver events and mutational complexity
JOURNAL Nat. Genet. 45 (5), 478-486 (2013)
PUBMED 23525077
REMARK GeneRIF: ELMO1 mutations are associated with esophageal
adenocarcinoma.
REFERENCE 2 (bases 1 to 5335)
AUTHORS Sherva,R., Tripodis,Y., Bennett,D.A., Chibnik,L.B., Crane,P.K., de
Jager,P.L., Farrer,L.A., Saykin,A.J., Shulman,J.M. and Green,R.C.
CONSRTM The GENAROADS Consortium, and The Alzheimer's Disease Neuroimaging
Initiative
TITLE Genome-wide association study of the rate of cognitive decline in
Alzheimer's disease
JOURNAL Alzheimers Dement (2013) In press
PUBMED 23535033
REMARK Publication Status: Available-Online prior to print
REFERENCE 3 (bases 1 to 5335)
AUTHORS Lauc,G., Huffman,J.E., Pucic,M., Zgaga,L., Adamczyk,B., Muzinic,A.,
Novokmet,M., Polasek,O., Gornik,O., Kristic,J., Keser,T.,
Vitart,V., Scheijen,B., Uh,H.W., Molokhia,M., Patrick,A.L.,
McKeigue,P., Kolcic,I., Lukic,I.K., Swann,O., van Leeuwen,F.N.,
Ruhaak,L.R., Houwing-Duistermaat,J.J., Slagboom,P.E., Beekman,M.,
de Craen,A.J., Deelder,A.M., Zeng,Q., Wang,W., Hastie,N.D.,
Gyllensten,U., Wilson,J.F., Wuhrer,M., Wright,A.F., Rudd,P.M.,
Hayward,C., Aulchenko,Y., Campbell,H. and Rudan,I.
TITLE Loci associated with N-glycosylation of human immunoglobulin G show
pleiotropy with autoimmune diseases and haematological cancers
JOURNAL PLoS Genet. 9 (1), E1003225 (2013)
PUBMED 23382691
REFERENCE 4 (bases 1 to 5335)
AUTHORS Maeda,S.
TITLE [Genetic study for diabetic microvascular complications--recent
advances and future perspectives]
JOURNAL Nippon Rinsho 70 (SUPPL 5), 219-225 (2012)
PUBMED 23156397
REMARK GeneRIF: Analysis of SNP databases of Japanese patuients with
diabetic nephropathy revealed ELMO1 as a gene related to the
above-cited diabetic complication.
REFERENCE 5 (bases 1 to 5335)
AUTHORS Shimazaki,A., Kawamura,Y., Kanazawa,A., Sekine,A., Saito,S.,
Tsunoda,T., Koya,D., Babazono,T., Tanaka,Y., Matsuda,M., Kawai,K.,
Iiizumi,T., Imanishi,M., Shinosaki,T., Yanagimoto,T., Ikeda,M.,
Omachi,S., Kashiwagi,A., Kaku,K., Iwamoto,Y., Kawamori,R.,
Kikkawa,R., Nakajima,M., Nakamura,Y. and Maeda,S.
TITLE Genetic variations in the gene encoding ELMO1 are associated with
susceptibility to diabetic nephropathy
JOURNAL Diabetes 54 (4), 1171-1178 (2005)
PUBMED 15793258
REMARK GeneRIF: These results indicate that ELMO1 is a novel candidate
gene that both confers susceptibility to diabetic nephropathy and
plays an important role in the development and progression of this
disease.
GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 6 (bases 1 to 5335)
AUTHORS Sanui,T., Inayoshi,A., Noda,M., Iwata,E., Stein,J.V., Sasazuki,T.
and Fukui,Y.
TITLE DOCK2 regulates Rac activation and cytoskeletal reorganization
through interaction with ELMO1
JOURNAL Blood 102 (8), 2948-2950 (2003)
PUBMED 12829596
REMARK GeneRIF: the association of DOCK2 with ELMO1 is critical for
DOCK2-mediated Rac activation, thereby suggesting that their
association might be a therapeutic target for immunologic disorders
caused by lymphocyte infiltration
REFERENCE 7 (bases 1 to 5335)
AUTHORS Katoh,H. and Negishi,M.
TITLE RhoG activates Rac1 by direct interaction with the Dock180-binding
protein Elmo
JOURNAL Nature 424 (6947), 461-464 (2003)
PUBMED 12879077
REFERENCE 8 (bases 1 to 5335)
AUTHORS Scott,M.P., Zappacosta,F., Kim,E.Y., Annan,R.S. and Miller,W.T.
TITLE Identification of novel SH3 domain ligands for the Src family
kinase Hck. Wiskott-Aldrich syndrome protein (WASP),
WASP-interacting protein (WIP), and ELMO1
JOURNAL J. Biol. Chem. 277 (31), 28238-28246 (2002)
PUBMED 12029088
REFERENCE 9 (bases 1 to 5335)
AUTHORS Brugnera,E., Haney,L., Grimsley,C., Lu,M., Walk,S.F.,
Tosello-Trampont,A.C., Macara,I.G., Madhani,H., Fink,G.R. and
Ravichandran,K.S.
TITLE Unconventional Rac-GEF activity is mediated through the
Dock180-ELMO complex
JOURNAL Nat. Cell Biol. 4 (8), 574-582 (2002)
PUBMED 12134158
REMARK GeneRIF: Dock180 ELMO complex functions as an unconventional
two-part exchange factor for Rac.
REFERENCE 10 (bases 1 to 5335)
AUTHORS Gumienny,T.L., Brugnera,E., Tosello-Trampont,A.C., Kinchen,J.M.,
Haney,L.B., Nishiwaki,K., Walk,S.F., Nemergut,M.E., Macara,I.G.,
Francis,R., Schedl,T., Qin,Y., Van Aelst,L., Hengartner,M.O. and
Ravichandran,K.S.
TITLE CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is
required for phagocytosis and cell migration
JOURNAL Cell 107 (1), 27-41 (2001)
PUBMED 11595183
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AC078843.2, AC083861.2,
AC007444.1, AC009196.14, AC078844.2 and AC007349.1.
Summary: This gene encodes a member of the engulfment and cell
motility protein family. These proteins interact with dedicator of
cytokinesis proteins to promote phagocytosis and cell migration.
Increased expression of this gene and dedicator of cytokinesis 1
may promote glioma cell invasion, and single nucleotide
polymorphisms in this gene may be associated with diabetic
nephropathy. Alternatively spliced transcript variants encoding
multiple isoforms have been observed for this gene. [provided by
RefSeq, Apr 2011].
Transcript Variant: This variant (4) differs in the 5' UTR,
compared to variant 1. Variants 1, 4 and 5 encode the same isoform
(1).
Sequence Note: The RefSeq transcript and protein were derived from
genomic sequence to make the sequence consistent with the reference
genome assembly. The genomic coordinates used for the transcript
record were based on alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AK314349.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025081, ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-433 AC078843.2 26776-27208
434-584 AC083861.2 122983-123133 c
585-625 AC083861.2 96290-96330 c
626-698 AC083861.2 95220-95292 c
699-749 AC083861.2 52203-52253 c
750-919 AC007444.1 144532-144701 c
920-955 AC007444.1 129707-129742 c
956-1055 AC007444.1 118446-118545 c
1056-1207 AC007444.1 110230-110381 c
1208-1286 AC007444.1 107966-108044 c
1287-1337 AC007444.1 101996-102046 c
1338-1460 AC007444.1 98686-98808 c
1461-1592 AC007444.1 96737-96868 c
1593-1697 AC009196.14 166907-167011 c
1698-1806 AC009196.14 130396-130504 c
1807-1943 AC009196.14 47076-47212 c
1944-2107 AC078844.2 10239-10402 c
2108-2220 AC078844.2 2945-3057 c
2221-2328 AC007349.1 147819-147926 c
2329-2411 AC007349.1 140202-140284 c
2412-2489 AC007349.1 131468-131545 c
2490-5335 AC007349.1 122715-125560 c
FEATURES Location/Qualifiers
source 1..5335
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="7"
/map="7p14.1"
gene 1..5335
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/note="engulfment and cell motility 1"
/db_xref="GeneID:9844"
/db_xref="HGNC:16286"
/db_xref="MIM:606420"
exon 1..433
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 434..584
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
misc_feature 486..488
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/note="upstream in-frame stop codon"
CDS 507..2690
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/note="isoform 1 is encoded by transcript variant 4;
engulfment and cell motility protein 1; ced-12 homolog 1"
/codon_start=1
/product="engulfment and cell motility protein 1 isoform
1"
/protein_id="NP_001193409.1"
/db_xref="GI:330688434"
/db_xref="CCDS:CCDS5449.1"
/db_xref="GeneID:9844"
/db_xref="HGNC:16286"
/db_xref="MIM:606420"
/translation="
MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFYITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEFINLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQTYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN
"
misc_feature 558..560
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphotyrosine, by HCK; propagated from
UniProtKB/Swiss-Prot (Q92556.2); phosphorylation site"
misc_feature 804..806
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine; propagated from
UniProtKB/Swiss-Prot (Q92556.2); acetylation site"
misc_feature 819..821
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine; propagated from
UniProtKB/Swiss-Prot (Q92556.2); acetylation site"
misc_feature 846..1349
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/note="Domain of unknown function (DUF3361); Region:
DUF3361; pfam11841"
/db_xref="CDD:192850"
misc_feature 1152..1154
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphotyrosine, by HCK; propagated from
UniProtKB/Swiss-Prot (Q92556.2); phosphorylation site"
misc_feature 1404..1952
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/note="ELMO/CED-12 family; Region: ELMO_CED12; pfam04727"
/db_xref="CDD:203077"
misc_feature 1689..1691
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphotyrosine, by HCK; propagated from
UniProtKB/Swiss-Prot (Q92556.2); phosphorylation site"
misc_feature 2037..2039
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphotyrosine, by HCK; propagated from
UniProtKB/Swiss-Prot (Q92556.2); phosphorylation site"
misc_feature <2319..2522
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/note="Pleckstrin homology-like domain; Region: PH-like;
cl00273"
/db_xref="CDD:206947"
misc_feature 2625..2648
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q92556.2);
Region: SH3-binding"
misc_feature 2664..2666
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphotyrosine, by HCK; propagated from
UniProtKB/Swiss-Prot (Q92556.2); phosphorylation site"
exon 585..625
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
STS 607..684
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/standard_name="GDB:4585326"
/db_xref="UniSTS:11479"
exon 626..698
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 699..749
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 750..919
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 920..955
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 956..1055
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 1056..1207
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 1208..1286
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 1287..1337
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 1338..1460
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 1461..1592
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 1593..1697
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 1698..1806
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 1807..1943
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 1944..2107
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 2108..2220
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 2221..2328
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 2329..2411
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 2412..2489
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
exon 2490..5335
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/inference="alignment:Splign:1.39.8"
STS 3110..3930
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/standard_name="ELMO1_9004"
/db_xref="UniSTS:468402"
variation 3495
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:14392"
STS 3720..3869
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
/standard_name="WI-16086"
/db_xref="UniSTS:29007"
polyA_signal 3861..3866
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
polyA_site 3880
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
polyA_signal 5311..5316
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
polyA_site 5335
/gene="ELMO1"
/gene_synonym="CED-12; CED12; ELMO-1"
ORIGIN
gcttttggcctcccggagatggcgctatgagggtgacggagttaattagtgcctccaaacgccgtgtgtgagctcatcgaagtcatgctctgcacacatattatttatagcagatctgaggcatgcatggtgtttgacatttctgtcttttaagtagggggacttcaaaaagtcgtgggcatccccctaggcaaagtgcagtgggcagggaccaggcagggtgcgggcgcaaggcgaacgcgcagaccacgagtgtcctggcgcaggtgccgggggcggcggctgcaactccgcagcgtccgctcgggaggagagttcgcggctgatctccggatgccttgcagatgcaaaatgtgtctctggccagcaggaggaaggaagaggaagtgagagcagcggcagccggcggtgcagcagccggccgacccagagtgtatagacacgtgtggccgtttacgctgtaggatcctcattcccactggctttgaacattttggggacttacaatgccgccacccgcggacatcgtcaaggtggccatagaatggccgggcgcctaccccaaactcatggaaattgatcagaaaaaaccactgtctgcaataataaaggaagtctgtgatgggtggtctcttgccaaccatgaatattttgcactccagcatgccgatagttcaaacttctatatcacagaaaagaaccgcaatgagataaaaaatggcactatccttcgattaaccacatctccagctcagaacgcccagcagctccatgaacgaatccagtcctcgagtatggatgccaagctggaagccctgaaggacttggccagcctctcccgggatgtcacgtttgcccaggagtttataaacctggacggtatctctctcctcacgcagatggtggagagcggcactgagcgataccagaaattgcagaagatcatgaagccttgctttggagacatgctgtccttcaccctgacggccttcgttgagctgatggaccatggcatagtgtcctgggatacattttcggtggcgttcattaagaagatagcaagttttgtgaacaagtcagccatagacatctcgatcctgcagcggtccttggccattttggagtcgatggtgctcaatagccatgacctctaccagaaagtggcgcaggagatcaccatcggccagctcattccacacctgcaagggtcagatcaagaaatccaaacctatactattgcagtgattaatgcgcttttcctgaaggctcctgatgagaggaggcaggagatggcgaatattttggctcagaagcaactgcgttccatcattttaacacatgtcatccgagcccagcgggccatcaacaatgagatggcgcaccagctgtatgttctacaagtgctcacctttaacctcctggaagacaggatgatgaccaaaatggacccccaggaccaggctcagagggacatcatatttgaacttcgaagaattgcttttgatgctgagtctgaacctaacaacagcagtggcagcatggagaaacgcaagtccatgtacacgcgagattataagaagcttgggttcattaatcatgtcaaccctgccatggacttcacgcagactccacctgggatgttggctctggacaacatgctgtactttgccaagcaccaccaagatgcctacatccggattgtgcttgagaacagtagtcgagaagacaagcatgaatgtccctttggccgcagtagtatagagctgaccaagatgctatgtgagatcttgaaagtgggcgagttgcctagtgagacctgcaacgacttccacccgatgttcttcacccacgacagatcctttgaggagtttttctgcatctgtatccagctcctgaacaagacatggaaggaaatgagggcaacttctgaagacttcaacaaggtaatgcaggtggtgaaggagcaggttatgagagcacttacaaccaagcctagctccctggaccagttcaagagcaaactgcagaacctgagctacactgagatcctgaaaatccgccagtccgagaggatgaaccaggaagatttccagtcccgcccgattttggaactaaaggagaagattcagccagaaatcttagagctgatcaaacagcaacgcctgaaccgccttgtggaagggacctgctttaggaaactcaatgcccggcggaggcaagacaagttttggtattgtcggctttcgccaaatcacaaagtcctgcattacggagacttagaagagagtcctcagggagaagtgccccacgattccttgcaggacaaactgccggtggcagatatcaaagccgtggtgacgggaaaggactgccctcatatgaaagagaaaggtgcccttaaacaaaacaaggaggtgcttgaactcgctttctccatcttgtatgactcaaactgccaactgaacttcatcgctcctgacaagcatgagtactgtatctggacggatggactgaatgcgctactcgggaaggacatgatgagcgacctgacgcggaatgacctggacaccctgctcagcatggaaatcaagctccgcctcctggacctggaaaacatccagatccctgacgcacctccgccgattcccaaggagcccagcaactatgacttcgtctatgactgtaactgaagtggccgggcccagacatgccccttccaaaactggaacacctagctaacaggagagaggaatgaaaacacacccacgccttggaaccgtcctttggtaaagggaagctgtgggtccacattcccttcagcatcacctctagccctggcaactttcagcccctagctggcatcttgctcaccgccctgattctgttcctcggctccactgcttcaggtcacttcccatggctgcagtccactggtgggacaagagcaaagcccactgccagtaagaaggccaaagggcccttccatcctagccctctgcaggcatgcccttccttcccttgggcaggaaagccagcagccccagactgcccaaaaacttgcccaccagaccaagggcagtgccccaaggcccctgtctggaggaaatggcctagctatttgatgagaagaccaaaccccacatcctcctttcccctctctctagaatcatctcgcaccaccagttacacttgaattaagatctgcgctcaaatctcctcccacctctctccctgcttttgccttgctctgttcctctttggtcccaagagcagcagccgcagcctcctcgtgatcctccctagcataaatttcccaaacagtccacaggtcccatgcccactttgcgtctgcactgtgatcgtgacaaatcttccctcctcaccagctagtctggggtttcctctccctgccccaggccagaactgccttcttcatttccacccacgctcccagcctcttagctgaaagcacaaatggtgaaatcagtagtctcgctccatctctaatagactaaacctaaatgcctctaggacggactgttgctatccaagcgtttggtgttaccttctcctgggaggtcctgctgcaactcaagttccacaggatggtcaagctgtcagacatccaagtttacatcattgtaattattactggtatttacaatttgcaagagttttgggttagtttttttttttttttttgctttgtttttgtacaaaagagtctaacattttttgccaaacagatatatatttaatgaaaagaagagatacataaatgtgtgaatttccagtttttttttaattattttaatcccaaacatcttcctgaaaataacattcccttaaacatgctgtggaataaaatggattgtgatgatttggggagctggtgttttgatttagtaacttaggttcttgctactcagtcatcagcatcacctgggagcttgttggagatgccagctcttcagctccaccctagacctgctgaattgggtgatgtttatgtacattggtttgaaaaacactgctgtgggaaaccctccaccattgctaggtcaccataggctctgagcatcagtggagaatgttacttctaagaagaccatctcgactcactgagaaaatcagacccactgtatgaaaatatctattccttttacattgctgtctcttgaccatgactttctcttttttctttcttaccatgatataatttatagaatgggtctaattaaagacatcacaactttgagggagcacatttagcaatgaaaagaatgcatacccacagacctgaaataagccagaactaaataaatctaaccgtgggttaataaattataggtcagagcccagcgaaggatgtttcttaagtcatttgcactggaggcattatcaggattgtaaactcccagcactgggagggatgtcagaagggtccaagcatgcagtattaagcgtggcacagcaccagccactctggcctcacagcacaagctgtggaagcatccaggtcatttctctttaccgtcatcaggatgtgcaattacagattgacctgggttgagatgatatggtccagagcactgcatgcattgcaggaaaaaagtcctttgcattcacaggggttccttcttcccatcagagcactcacacctgtgtcaagctgttaattccttgatcattaagcttcgatgttattaacatgtacttgctatcaggagcagttattaatctacccatcatcatgataaaacagtaagtgttaggtcaaaggcagcaaacaaagtcatattatttttttcttatgggttacaagatccaatccatgaaaaagggaactttctggaccaggatctctgaggtcctgagacactgggtttaagaaatgtatctgtcctgtgaccttggttggggagatccagcccctctctcttctggcactccagctttggtgcatttaatagaaagaaaccttttcaggactatgaaaggcagcattctccagctcctccctagaccctcctttggacctgtgagatctgaagagtatgccatctgtttccattcattttgtgaccatgtggggaaggattgttgcccatatttggccacctcaccttctctctccaggctgcccaaggctttttttcccatgcaatgagcctaccacctccaactcatctcctgttgcctgcagtttcctaagcctgggcaactcagccaaatccaaggcagaagtaaagtaggaagactgatgttgtcgtgaagtccaagttgcattctgctattcatattactcaaaataaaactgattacttaatttgaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:9844 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:9844 -> Molecular function: GO:0005543 [phospholipid binding] evidence: IEA
GeneID:9844 -> Molecular function: GO:0017124 [SH3 domain binding] evidence: IPI
GeneID:9844 -> Biological process: GO:0006911 [phagocytosis, engulfment] evidence: IGI
GeneID:9844 -> Biological process: GO:0006915 [apoptotic process] evidence: NAS
GeneID:9844 -> Biological process: GO:0006928 [cellular component movement] evidence: IGI
GeneID:9844 -> Biological process: GO:0016032 [viral process] evidence: TAS
GeneID:9844 -> Biological process: GO:0016601 [Rac protein signal transduction] evidence: IGI
GeneID:9844 -> Biological process: GO:0030036 [actin cytoskeleton organization] evidence: IGI
GeneID:9844 -> Biological process: GO:0038096 [Fc-gamma receptor signaling pathway involved in phagocytosis] evidence: TAS
GeneID:9844 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
GeneID:9844 -> Biological process: GO:0050690 [regulation of defense response to virus by virus] evidence: TAS
GeneID:9844 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:9844 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:9844 -> Cellular component: GO:0005856 [cytoskeleton] evidence: IEA
GeneID:9844 -> Cellular component: GO:0005886 [plasma membrane] evidence: IDA
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.