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2024-03-29 01:10:21, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001204878            4370 bp    mRNA    linear   PRI 15-JUL-2013
DEFINITION  Homo sapiens BCL2-associated athanogene 4 (BAG4), transcript
            variant 2, mRNA.
ACCESSION   NM_001204878
VERSION     NM_001204878.1  GI:325910868
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4370)
  AUTHORS   Reuland,S.N., Smith,S.M., Bemis,L.T., Goldstein,N.B., Almeida,A.R.,
            Partyka,K.A., Marquez,V.E., Zhang,Q., Norris,D.A. and Shellman,Y.G.
  TITLE     MicroRNA-26a is strongly downregulated in melanoma and induces cell
            death through repression of silencer of death domains (SODD)
  JOURNAL   J. Invest. Dermatol. 133 (5), 1286-1293 (2013)
   PUBMED   23190898
  REMARK    GeneRIF: MicroRNA-26a is strongly downregulated in melanoma and
            induces cell death through repression of silencer of death domains
            (SODD).
REFERENCE   2  (bases 1 to 4370)
  AUTHORS   Kelly,J.L., Novak,A.J., Fredericksen,Z.S., Liebow,M., Ansell,S.M.,
            Dogan,A., Wang,A.H., Witzig,T.E., Call,T.G., Kay,N.E.,
            Habermann,T.M., Slager,S.L. and Cerhan,J.R.
  TITLE     Germline variation in apoptosis pathway genes and risk of
            non-Hodgkin's lymphoma
  JOURNAL   Cancer Epidemiol. Biomarkers Prev. 19 (11), 2847-2858 (2010)
   PUBMED   20855536
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   3  (bases 1 to 4370)
  AUTHORS   Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B,
            Yusuf S, Gerstein HC, Engert JC and Anand S.
  CONSRTM   DREAM investigators
  TITLE     Variation at the NFATC2 locus increases the risk of
            thiazolidinedione-induced edema in the Diabetes REduction
            Assessment with ramipril and rosiglitazone Medication (DREAM) study
  JOURNAL   Diabetes Care 33 (10), 2250-2253 (2010)
   PUBMED   20628086
  REMARK    GeneRIF: Observational study of gene-disease association,
            gene-environment interaction, and pharmacogenomic / toxicogenomic.
            (HuGE Navigator)
REFERENCE   4  (bases 1 to 4370)
  AUTHORS   Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt
            TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M,
            Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ,
            Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S,
            Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD,
            Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE
            and Hingorani AD.
  CONSRTM   ASCOT investigators; NORDIL investigators; BRIGHT Consortium
  TITLE     Gene-centric association signals for lipids and apolipoproteins
            identified via the HumanCVD BeadChip
  JOURNAL   Am. J. Hum. Genet. 85 (5), 628-642 (2009)
   PUBMED   19913121
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   5  (bases 1 to 4370)
  AUTHORS   Tao,H.F., Hu,Q., Fang,J.L., Liu,A.G., Liu,S.Y., Zhang,L.Q. and
            Hu,Y.
  TITLE     [Effects of SODD and survivin on leukemia cell apoptosis induced by
            chemotherapeutic drugs]
  JOURNAL   Zhongguo Shi Yan Xue Ye Xue Za Zhi 15 (3), 501-505 (2007)
   PUBMED   17605853
  REMARK    GeneRIF: Vincristine induces Jurkat cell apoptosis by
            downregulating expression of SODD protein and priming the death
            receptor pathway.
REFERENCE   6  (bases 1 to 4370)
  AUTHORS   Eichholtz-Wirth,H. and Sagan,D.
  TITLE     Altered signaling of TNFalpha-TNFR1 and SODD/BAG4 is responsible
            for radioresistance in human HT-R15 cells
  JOURNAL   Anticancer Res. 22 (1A), 235-240 (2002)
   PUBMED   12017295
  REMARK    GeneRIF: Altered signaling of TNFalpha-TNFR1 and SODD/BAG4 is
            responsible for radioresistance in human HT-R15 cells.
REFERENCE   7  (bases 1 to 4370)
  AUTHORS   Antoku,K., Maser,R.S., Scully,W.J. Jr., Delach,S.M. and
            Johnson,D.E.
  TITLE     Isolation of Bcl-2 binding proteins that exhibit homology with
            BAG-1 and suppressor of death domains protein
  JOURNAL   Biochem. Biophys. Res. Commun. 286 (5), 1003-1010 (2001)
   PUBMED   11527400
REFERENCE   8  (bases 1 to 4370)
  AUTHORS   Frisch,S.M.
  TITLE     Evidence for a function of death-receptor-related,
            death-domain-containing proteins in anoikis
  JOURNAL   Curr. Biol. 9 (18), 1047-1049 (1999)
   PUBMED   10508612
REFERENCE   9  (bases 1 to 4370)
  AUTHORS   Jiang,Y., Woronicz,J.D., Liu,W. and Goeddel,D.V.
  TITLE     Prevention of constitutive TNF receptor 1 signaling by silencer of
            death domains
  JOURNAL   Science 283 (5401), 543-546 (1999)
   PUBMED   9915703
  REMARK    Erratum:[Science 1999 Mar 19;283(5409):1852]
REFERENCE   10 (bases 1 to 4370)
  AUTHORS   Takayama,S., Xie,Z. and Reed,J.C.
  TITLE     An evolutionarily conserved family of Hsp70/Hsc70 molecular
            chaperone regulators
  JOURNAL   J. Biol. Chem. 274 (2), 781-786 (1999)
   PUBMED   9873016
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC000800.1, AC084024.17 and
            BM683128.1.
            
            Summary: The protein encoded by this gene is a member of the
            BAG1-related protein family. BAG1 is an anti-apoptotic protein that
            functions through interactions with a variety of cell apoptosis and
            growth related proteins including BCL-2, Raf-protein kinase,
            steroid hormone receptors, growth factor receptors and members of
            the heat shock protein 70 kDa family. This protein contains a BAG
            domain near the C-terminus, which could bind and inhibit the
            chaperone activity of Hsc70/Hsp70. This protein was found to be
            associated with the death domain of tumor necrosis factor receptor
            type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively
            regulates downstream cell death signaling. The regulatory role of
            this protein in cell death was demonstrated in epithelial cells
            which undergo apoptosis while integrin mediated matrix contacts are
            lost. Alternatively spliced transcript variants encoding distinct
            isoforms have been identified. [provided by RefSeq, Mar 2011].
            
            Transcript Variant: This variant (2) lacks an in-frame coding exon,
            compared to variant 1. The resulting isoform (2) lacks an internal
            segment, compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC000800.1, AK304072.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025082 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1539              BC000800.1         1-1539
            1540-3884           AC084024.17        96142-98486
            3885-4370           BM683128.1         1-486               c
FEATURES             Location/Qualifiers
     source          1..4370
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8p11.23"
     gene            1..4370
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /note="BCL2-associated athanogene 4"
                     /db_xref="GeneID:9530"
                     /db_xref="HGNC:940"
                     /db_xref="MIM:603884"
     exon            1..552
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /inference="alignment:Splign:1.39.8"
     variation       23
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150735540"
     variation       35..36
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:34846134"
     variation       89
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:7000184"
     variation       90
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113937856"
     misc_feature    106..108
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /note="upstream in-frame stop codon"
     variation       109
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:77568784"
     variation       177
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:112343580"
     variation       179
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:55962869"
     variation       237
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143677476"
     variation       244
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190213515"
     variation       273
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:376268617"
     CDS             283..1548
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /note="isoform 2 is encoded by transcript variant 2;
                     BAG-family molecular chaperone regulator-4; silencer of
                     death domains; BAG family molecular chaperone regulator 4;
                     bcl-2-associated athanogene 4"
                     /codon_start=1
                     /product="BAG family molecular chaperone regulator 4
                     isoform 2"
                     /protein_id="NP_001191807.1"
                     /db_xref="GI:325910869"
                     /db_xref="CCDS:CCDS56533.1"
                     /db_xref="GeneID:9530"
                     /db_xref="HGNC:940"
                     /db_xref="MIM:603884"
                     /translation="
MSALRRSGYGPSDGPSYGRYYGPGGGDVPVHPPPPLYPLRPEPPQPPISWRVRGGGPAETTWLGEGGGGDGYYPSGGAWPEPGRAGGSHQSLNSYTNGAYGPTYPPGPGANTASYSGAYYAPGYTQTSYSTEVPSTYRSSGNSPTPVSRWIYPQQDCQTEAPPLRGQVPGYPPSQNPGMTLPHYPYGDGNRSVPQSGPTVRPQEDAWASPGAYGMGGRYPWPSSAPSAPPGNLYMTESTSPWPSSGSPQSPPSPPVQQPKDSSYPYSQSDQSMNRHNFPCSVHQYESSGTVNNDDSDLLDSQVQYSAEPQLYGNATSDHPNNQDQSSSLPEECVPSDESTPPSIKKIIHVLEKVQYLEQEVEEFVGKKTDKAYWLLEEMLTKELLELDSVETGGQDSVRQARKEAVCKIQAILEKLEKKGL
"
     misc_feature    1309..1542
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /note="BAG domains, present in regulator of Hsp70
                     proteins; Region: BAG; smart00264"
                     /db_xref="CDD:197613"
     variation       297
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61731143"
     variation       353
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369467061"
     variation       355
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61731142"
     variation       479
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:35041562"
     variation       507
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369666639"
     exon            553..807
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /inference="alignment:Splign:1.39.8"
     variation       562
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377544370"
     variation       569
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:371334530"
     variation       573
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375515884"
     variation       589
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:192353336"
     variation       598
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377654190"
     variation       648
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374977832"
     variation       684
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:17853839"
     variation       691
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140270832"
     variation       694
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375790383"
     variation       718
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:367677262"
     variation       724
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:143334197"
     variation       728
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61754115"
     variation       732
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:372261481"
     variation       751
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:139408020"
     variation       769
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:150045830"
     variation       797
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200494674"
     exon            808..1062
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /inference="alignment:Splign:1.39.8"
     variation       847
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145302681"
     variation       856
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:369685431"
     variation       867
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190953663"
     variation       890
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111978086"
     variation       899
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202100571"
     variation       900
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140078461"
     variation       916
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143665459"
     variation       949
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201302425"
     variation       957
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146791444"
     variation       971
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376249751"
     exon            1063..4356
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /inference="alignment:Splign:1.39.8"
     variation       1065
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:147569371"
     variation       1096
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:140547293"
     variation       1112
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140266447"
     variation       1127
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143644289"
     variation       1146
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151234579"
     variation       1162
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201044060"
     variation       1178
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199793591"
     variation       1269
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201309879"
     variation       1304
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376216479"
     variation       1307
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140388982"
     variation       1308
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377644522"
     variation       1343
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371081339"
     variation       1347
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:376393739"
     variation       1363
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150352965"
     STS             1373..1502
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /standard_name="SGC34731"
                     /db_xref="UniSTS:22143"
     STS             1396..2142
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /standard_name="BAG4_88"
                     /db_xref="UniSTS:277023"
     variation       1408
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10725"
     variation       1422
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200905499"
     variation       1464
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:374076675"
     variation       1555
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:187571848"
     variation       1637
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377003478"
     variation       1640
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:111385150"
     variation       1661
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:80041165"
     variation       1743
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:193259612"
     STS             1847..2035
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /standard_name="RH78257"
                     /db_xref="UniSTS:21968"
     variation       1861
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1043782"
     STS             1928..2053
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /standard_name="SHGC-30117"
                     /db_xref="UniSTS:1122"
     variation       1957
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3313"
     variation       2055
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:144321800"
     variation       2151..2152
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:371085485"
     variation       2257
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:76098501"
     variation       2259
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:79588397"
     variation       2280..2281
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:72159699"
     variation       2334
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:184097066"
     variation       2335..2341
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace=""
                     /replace="ataaaat"
                     /db_xref="dbSNP:144659234"
     variation       2343
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112471179"
     variation       2383
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:4579494"
     variation       2439
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:78509021"
     variation       2448
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:142140385"
     variation       2542..2543
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:34203247"
     variation       2559
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:113784638"
     variation       2583
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:187833453"
     STS             2601..2689
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /standard_name="D8S1432E"
                     /db_xref="UniSTS:151221"
     STS             2617..2822
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /standard_name="RH25151"
                     /db_xref="UniSTS:88759"
     variation       2680
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:142541037"
     variation       2801
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:192460147"
     variation       2898
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:184086295"
     variation       2969
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143366565"
     variation       3045
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:60530611"
     variation       3100
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:188766347"
     variation       3134
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372784467"
     variation       3264
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113567191"
     variation       3282
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372560655"
     variation       3326..3329
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace=""
                     /replace="ttac"
                     /db_xref="dbSNP:370930659"
     variation       3469
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:192014496"
     variation       3502..3503
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:36118987"
     variation       3511
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184563970"
     variation       3568
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:190199472"
     variation       3624
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:76228049"
     variation       3665
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:35866749"
     variation       3840
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:182385280"
     variation       3922
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187376240"
     variation       4206
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138231001"
     variation       4216
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:189383231"
     variation       4260
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:180939735"
     polyA_signal    4322..4327
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
     variation       4340
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:142725480"
     polyA_site      4356
                     /gene="BAG4"
                     /gene_synonym="BAG-4; SODD"
ORIGIN      
aggtaagaggaaactccattggataaatggcgaggaaacgtatactccctcttaaggaacacggtgtcttccttcgtctccgggttcccgagaccccagagtcactgacctccgtccctcagctttcggggttcggcagcagaaggggcgggcccgggcctgggattggctggcgtcgtccgacccccttcgctgctctccattcgcaatcgcccgcgggcgcctgcgcgatgggtcggccgtggggagcggggcgggaagcgcttcagggcagcggatcccatgtcggccctgaggcgctcgggctacggccccagtgacggtccgtcctacggccgctactacgggcctgggggtggagatgtgccggtacacccacctccacccttatatcctcttcgccctgaacctccccagcctcccatttcctggcgggtgcgcgggggcggcccggcggagaccacctggctgggagaaggcggaggaggcgatggctactatccctcgggaggcgcctggccagagcctggtcgagccggaggaagccaccagagtttgaattcttatacaaatggagcgtatggtccaacataccccccaggccctggggcaaatactgcctcatactcaggggcttattatgcacctggttatactcagaccagttactccacagaagttccaagtacttaccgttcatctggcaacagcccaactccagtctctcgttggatctatccccagcaggactgtcagactgaagcaccccctcttagggggcaggttccaggatatccgccttcacagaaccctggaatgaccctgccccattatccttatggagatggtaatcgtagtgttccacaatcaggaccgactgtacgaccacaagaagatgcgtgggcttctcctggtgcttatggaatgggtggccgttatccctggccttcatcagcgccctcagcaccacccggcaatctctacatgactgaaagtacttcaccatggcctagcagtggctctccccagtcacccccttcacccccagtccagcagcccaaggattcttcatacccctatagccaatcagatcaaagcatgaaccggcacaactttccttgcagtgtccatcagtacgaatcctcggggacagtgaacaatgatgattcagatcttttggattcccaagtccagtatagtgctgagcctcagctgtatggtaatgccaccagtgaccatcccaacaatcaagatcaaagtagcagtcttcctgaagaatgtgtaccttcagatgaaagtactcctccgagtattaaaaaaatcatacatgtgctggagaaggtccagtatcttgaacaagaagtagaagaatttgtaggaaaaaagacagacaaagcatactggcttctggaagaaatgctaaccaaggaacttttggaactggattcagttgaaactgggggccaggactctgtacggcaggccagaaaagaggctgtttgtaagattcaggccatactggaaaaattagaaaaaaaaggattatgaaaggatttagaacaaagtggaagcctgttactaacttgaccaaagaacacttgatttggttaattaccctctttttgaaatgcctgttgatgacaagaagcaatacattccagctttcctttgattttatacttgaaaaactggcaaaggaatggaagaatattttagtcatgagttgttttcagttttcagacgaatgaatgtaataggaaactatggagttaccaatattgccaagtagactcactccttaaaaaatttatggatatctacaagctgcttcttaccagcaggagggaaacacacttcacacaacaggcttatcagaaacctaccagatgaaactggatataatctgagacaaacaggatgtgtttttttaaacatctggatatcttgtcacatttttgtacattgtgactgctttcaacatatacttcatgtgtaattatagcttagactttagccttcttggacttctgttttgttttgttatttgcagtttacaaatatagtattattctctacttcttggtacattttgtagtaatatgtttaatataattattcaagagactatattgacagccagatagtatggcagttctgaaaaaatttatatcttttcaccacttgaatatactgcaatgtgtagtgagtaaattgtctccctttttctatagatcattaggttagagtttttttcttcttttttttttttttttttttttaccacttctgctgttcatggtagtagtggaaggtaaatttggaaatggcattgacataaaatgaaaatgtttacggacacttttcttttttgcttttttattgtatttggataaagatccacttaaaagttatctgttttttcctgttttttttttttttccccaaagtgtagttatgttttcactattgctgcttctatagagggcattgtgatagagagttacagatgaaacattaaatgccacagtgagtagaaataattactacaaaaagtaataaatatgattacttggtaatatcattctccatctaaaatactagtttcacctgtgagcagatttcagctcagtttatagttaaaaacaatgagggtaaaatgggattcatgctcagggaatgaatcagccatagttagagtgggaaattattattttcttcatttaaaggtagattttatgtttatttccctaaattgcataagataaaattgtctgtttaataaaaagacatttattaccattattaacagtcattttagagccaaatttaagaaaaggatattgaaagggtctttattggccttgtttgggtaactctatgctgttagatagaagagacttaggtaaataactttttatgtctgaggtgagtacacaatattggttcttggaaaaatagctgtttcttcataagatacccaagtgataattttttttcccctagactgtcaggcctatgagtaaatactaaatctattagctgtccccactcataaaccaaaccaaaccaatacaaacagatgaggagaggaaatgtagtaaaaatactggctgggtcttatgattgggatgagtgattttataagataatatggtgataattttattctaggattttatttttggcctaatataggaatgtttaaaaaaggcttttctatgaaaattagaaatttatacttgaaattaaaagtctagaagggggaggaccttaaagctaagctaccagtaagacaatgaataattcagaagagaacactattcttttactgactgagtgcccaagatgccaatttccatgaagtcttgatttatatatatgtacacatgttatgcacatacatgtttgttttctaacagttattttttaagcttttgagataattttagacttacagaagagttgtaaaagtagtagagttcttgtatactctgcacccaccttgcccttatgttaacatcttacgtaacaatagaacatttgtcaaaattaagaaattaaccttgatataatactaactaaagtagaaagtttaaaaagtagagattttagtcttttcactaatgtccttttactgttccaagacccagccttgcatttagctatcatgcctacgtcctgtcttccagtctgtgacagtgtatcataacaggggatacctgatgttgtaatgtatttctggtgttgttaaccttgatcactatgctaaggtggtgtctgctaggattcgctactgtaaacttactgtgttttccttgtaattattgaatatttgctggagatacccggagactatgcaaatgtcccgtttctgcttaaacttttgctcattttactatccattggcagatcttgcttgtggcagttactactgtggtgttctaatggtgattttctatttctctcaatccttctacatttattattggaattcttctgtaaggaagagttgtcagttctggatttatatttttaactataataagatattcaggataagtatagatttagaacttaaagatgttaaatcatgttaaaattattccaaataccaatatcaaagaaaactaagttggtaatctatctcagaaaatatatgaacttaagaaggaaaatagtatttatgatttgtagaattggttcaacttttgacttaatactgactttggactgaattcaaagttttcttgaaatttcacatctggactttttaaagtgtctacatttatattactttggggatcattttgtcaaagtcttgaataaagttacccagtcctggcatgataaacacaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:9530 -> Molecular function: GO:0005057 [receptor signaling protein activity] evidence: TAS
            GeneID:9530 -> Molecular function: GO:0051087 [chaperone binding] evidence: IEA
            GeneID:9530 -> Biological process: GO:0006457 [protein folding] evidence: TAS
            GeneID:9530 -> Biological process: GO:0010763 [positive regulation of fibroblast migration] evidence: IEA
            GeneID:9530 -> Biological process: GO:0030838 [positive regulation of actin filament polymerization] evidence: IEA
            GeneID:9530 -> Biological process: GO:0033138 [positive regulation of peptidyl-serine phosphorylation] evidence: IEA
            GeneID:9530 -> Biological process: GO:0043066 [negative regulation of apoptotic process] evidence: TAS
            GeneID:9530 -> Biological process: GO:0045785 [positive regulation of cell adhesion] evidence: IEA
            GeneID:9530 -> Biological process: GO:0051496 [positive regulation of stress fiber assembly] evidence: IEA
            GeneID:9530 -> Biological process: GO:0051897 [positive regulation of protein kinase B signaling cascade] evidence: IEA
            GeneID:9530 -> Biological process: GO:0071356 [cellular response to tumor necrosis factor] evidence: IDA
            GeneID:9530 -> Biological process: GO:0071364 [cellular response to epidermal growth factor stimulus] evidence: IEA
            GeneID:9530 -> Biological process: GO:0072659 [protein localization to plasma membrane] evidence: IEA
            GeneID:9530 -> Biological process: GO:0097178 [ruffle assembly] evidence: IEA
            GeneID:9530 -> Biological process: GO:2001145 [negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity] evidence: IEA
            GeneID:9530 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:9530 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
            GeneID:9530 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:9530 -> Cellular component: GO:0005829 [cytosol] evidence: IDA
            GeneID:9530 -> Cellular component: GO:0005886 [plasma membrane] evidence: IDA

by @meso_cacase at DBCLS
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