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2024-04-20 20:34:41, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001204824 10717 bp mRNA linear PRI 01-JUL-2013
DEFINITION Homo sapiens potassium voltage-gated channel, KQT-like subfamily,
member 3 (KCNQ3), transcript variant 2, mRNA.
ACCESSION NM_001204824
VERSION NM_001204824.1 GI:325651929
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 10717)
AUTHORS Zara,F., Specchio,N., Striano,P., Robbiano,A., Gennaro,E.,
Paravidino,R., Vanni,N., Beccaria,F., Capovilla,G., Bianchi,A.,
Caffi,L., Cardilli,V., Darra,F., Bernardina,B.D., Fusco,L.,
Gaggero,R., Giordano,L., Guerrini,R., Incorpora,G., Mastrangelo,M.,
Spaccini,L., Laverda,A.M., Vecchi,M., Vanadia,F., Veggiotti,P.,
Viri,M., Occhi,G., Budetta,M., Taglialatela,M., Coviello,D.A.,
Vigevano,F. and Minetti,C.
TITLE Genetic testing in benign familial epilepsies of the first year of
life: clinical and diagnostic significance
JOURNAL Epilepsia 54 (3), 425-436 (2013)
PUBMED 23360469
REMARK GeneRIF: KCNQ3 mutations might be involved in families with
infantile seizures.
REFERENCE 2 (bases 1 to 10717)
AUTHORS Afawi,Z., Bassan,H., Heron,S., Oliver,K., Straussberg,R.,
Scheffer,I., Leventer,R., Korczyn,A. and Berkovic,S.
TITLE Benign neonatal sleep myoclonus: an autosomal dominant form not
allelic to KCNQ2 or KCNQ3
JOURNAL J. Child Neurol. 27 (10), 1260-1263 (2012)
PUBMED 22447848
REMARK GeneRIF: This study demonistrated that benign neonatal sleep
myoclonus can show autosomal dominant inheritance but not allelic
to KCNQ3.
REFERENCE 3 (bases 1 to 10717)
AUTHORS Stewart,A.P., Gomez-Posada,J.C., McGeorge,J., Rouhani,M.J.,
Villarroel,A., Murrell-Lagnado,R.D. and Edwardson,J.M.
TITLE The Kv7.2/Kv7.3 heterotetramer assembles with a random subunit
arrangement
JOURNAL J. Biol. Chem. 287 (15), 11870-11877 (2012)
PUBMED 22334706
REMARK GeneRIF: the Kv7.2-Kv7.3 heteromer assembles as a tetramer with a
predominantly 2:2 subunit stoichiometry and with a random subunit
arrangement.
REFERENCE 4 (bases 1 to 10717)
AUTHORS Cavaliere,S., Gillespie,J.M. and Hodge,J.J.
TITLE KCNQ channels show conserved ethanol block and function in ethanol
behaviour
JOURNAL PLoS ONE 7 (11), E50279 (2012)
PUBMED 23209695
REMARK GeneRIF: the single KCNQ channel in Drosophila (dKCNQ) has similar
electrophysiological properties to neuronal KCNQ2/3
REFERENCE 5 (bases 1 to 10717)
AUTHORS Gomez-Posada,J.C., Aivar,P., Alberdi,A., Alaimo,A., Etxeberria,A.,
Fernandez-Orth,J., Zamalloa,T., Roura-Ferrer,M., Villace,P.,
Areso,P., Casis,O. and Villarroel,A.
TITLE Kv7 channels can function without constitutive calmodulin tethering
JOURNAL PLoS ONE 6 (9), E25508 (2011)
PUBMED 21980481
REMARK GeneRIF: constitutive tethering of calmodulin is not required for
Kv7 channel function
REFERENCE 6 (bases 1 to 10717)
AUTHORS Schroeder,B.C., Kubisch,C., Stein,V. and Jentsch,T.J.
TITLE Moderate loss of function of cyclic-AMP-modulated KCNQ2/KCNQ3 K+
channels causes epilepsy
JOURNAL Nature 396 (6712), 687-690 (1998)
PUBMED 9872318
REFERENCE 7 (bases 1 to 10717)
AUTHORS Wang,H.S., Pan,Z., Shi,W., Brown,B.S., Wymore,R.S., Cohen,I.S.,
Dixon,J.E. and McKinnon,D.
TITLE KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of
the M-channel
JOURNAL Science 282 (5395), 1890-1893 (1998)
PUBMED 9836639
REFERENCE 8 (bases 1 to 10717)
AUTHORS Yang,W.P., Levesque,P.C., Little,W.A., Conder,M.L.,
Ramakrishnan,P., Neubauer,M.G. and Blanar,M.A.
TITLE Functional expression of two KvLQT1-related potassium channels
responsible for an inherited idiopathic epilepsy
JOURNAL J. Biol. Chem. 273 (31), 19419-19423 (1998)
PUBMED 9677360
REFERENCE 9 (bases 1 to 10717)
AUTHORS Charlier,C., Singh,N.A., Ryan,S.G., Lewis,T.B., Reus,B.E.,
Leach,R.J. and Leppert,M.
TITLE A pore mutation in a novel KQT-like potassium channel gene in an
idiopathic epilepsy family
JOURNAL Nat. Genet. 18 (1), 53-55 (1998)
PUBMED 9425900
REFERENCE 10 (bases 1 to 10717)
AUTHORS Ryan,S.G., Wiznitzer,M., Hollman,C., Torres,M.C., Szekeresova,M.
and Schneider,S.
TITLE Benign familial neonatal convulsions: evidence for clinical and
genetic heterogeneity
JOURNAL Ann. Neurol. 29 (5), 469-473 (1991)
PUBMED 1859177
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AK296293.1, AF033347.1,
AC131042.6 and BX538233.1.
Summary: The M channel is a slowly activating and deactivating
potassium channel that plays a critical role in the regulation of
neuronal excitability. The M channel is formed by the association
of the protein encoded by this gene and one of two related proteins
encoded by the KCNQ2 and KCNQ5 genes, both integral membrane
proteins. M channel currents are inhibited by M1 muscarinic
acetylcholine receptors and activated by retigabine, a novel
anti-convulsant drug. Defects in this gene are a cause of benign
familial neonatal convulsions type 2 (BFNC2), also known as
epilepsy, benign neonatal type 2 (EBN2). Two variants encoding
distinct isoforms have been found. [provided by RefSeq, Mar 2011].
Transcript Variant: This variant (2) has an alternate 5' exon, as
compared to variant 1. The resulting isoform (2) has a shorter and
distinct N-terminus, as compared to isoform 1.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
RNAseq introns :: mixed/partial sample support ERS025084
[ECO:0000350]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-373 AK296293.1 1-373
374-2548 AF033347.1 557-2731
2549-10519 AC131042.6 108257-116227
10520-10717 BX538233.1 4841-5038
FEATURES Location/Qualifiers
source 1..10717
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8q24"
gene 1..10717
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/note="potassium voltage-gated channel, KQT-like
subfamily, member 3"
/db_xref="GeneID:3786"
/db_xref="HGNC:6297"
/db_xref="MIM:602232"
exon 1..62
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="alignment:Splign:1.39.8"
misc_feature 7..9
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/note="upstream in-frame stop codon"
CDS 37..2295
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/note="isoform 2 precursor is encoded by transcript
variant 2; potassium channel, voltage-gated, subfamily Q,
member 3; potassium channel subunit alpha KvLQT3;
voltage-gated potassium channel subunit Kv7.3"
/codon_start=1
/product="potassium voltage-gated channel subfamily KQT
member 3 isoform 2 precursor"
/protein_id="NP_001191753.1"
/db_xref="GI:325651930"
/db_xref="CCDS:CCDS56554.1"
/db_xref="GeneID:3786"
/db_xref="HGNC:6297"
/db_xref="MIM:602232"
/translation="
MKPAEHATMFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAASSQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPTKGTSSPAEAEKKEDNRYSDLKTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNLPRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQGPYSDRISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPNGGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI
"
sig_peptide 37..105
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="COORDINATES: ab initio prediction:SignalP:4.0"
misc_feature 151..729
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/note="Ion transport protein; Region: Ion_trans;
pfam00520"
/db_xref="CDD:201279"
misc_feature 481..732
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/note="Ion channel; Region: Ion_trans_2; pfam07885"
/db_xref="CDD:203792"
misc_feature 1021..1674
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/note="KCNQ voltage-gated potassium channel; Region:
KCNQ_channel; pfam03520"
/db_xref="CDD:202676"
misc_feature 1981..2277
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/note="Ankyrin-G binding motif of KCNQ2-3; Region:
KCNQC3-Ank-G_bd; pfam11956"
/db_xref="CDD:204795"
exon 63..153
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="alignment:Splign:1.39.8"
exon 154..280
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="alignment:Splign:1.39.8"
exon 281..453
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="alignment:Splign:1.39.8"
exon 454..609
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="alignment:Splign:1.39.8"
exon 610..720
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="alignment:Splign:1.39.8"
exon 721..816
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="alignment:Splign:1.39.8"
STS 763..1001
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/standard_name="Kcnq3"
/db_xref="UniSTS:259499"
exon 817..911
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="alignment:Splign:1.39.8"
exon 912..938
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="alignment:Splign:1.39.8"
exon 939..1141
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="alignment:Splign:1.39.8"
exon 1142..1244
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="alignment:Splign:1.39.8"
exon 1245..1376
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="alignment:Splign:1.39.8"
exon 1377..1475
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="alignment:Splign:1.39.8"
exon 1476..1560
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="alignment:Splign:1.39.8"
exon 1561..10699
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/inference="alignment:Splign:1.39.8"
STS 1723..2549
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/standard_name="KCNQ3_350"
/db_xref="UniSTS:277435"
variation 3330
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/replace="a"
/replace="g"
/db_xref="dbSNP:2957046"
variation 4432
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/replace="c"
/replace="t"
/db_xref="dbSNP:2272679"
STS 4452..4601
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/standard_name="WI-14883"
/db_xref="UniSTS:68066"
variation 5327
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/replace="a"
/replace="g"
/db_xref="dbSNP:2469626"
variation 5330
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/replace="a"
/replace="g"
/db_xref="dbSNP:2469627"
variation 6272
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/replace="a"
/replace="g"
/db_xref="dbSNP:2469628"
STS 7108..7236
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/standard_name="RH47376"
/db_xref="UniSTS:10355"
variation 8635
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/replace="a"
/replace="g"
/db_xref="dbSNP:2469629"
variation 9251
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/replace="a"
/replace="g"
/db_xref="dbSNP:2469630"
STS 9488..9568
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
/standard_name="D8S1431E"
/db_xref="UniSTS:151220"
polyA_signal 10676..10681
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
polyA_site 10699
/gene="KCNQ3"
/gene_synonym="BFNC2; EBN2; KV7.3"
ORIGIN
acttgttaaaaatcttgttcttgcattcattaccttatgaagcctgcagaacacgccacgatgttcctgattgtcctggggtgcttgattctggctgtcctgaccacattcaaggagtatgagactgtctcgggagactggcttctgttactggagacatttgctattttcatctttggagccgagtttgctttgaggatctgggctgctggatgttgctgccgatacaaaggctggcggggccgactgaagtttgccaggaagcccctgtgcatgttggacatctttgtgctgattgcctctgtgccagtggttgctgtgggaaaccaaggcaatgttctggccacctccctgcgaagcctgcgcttcctgcagatcctgcgcatgctgcggatggaccggagaggtggcacctggaagcttctgggctcagccatctgtgcccacagcaaagaactcatcacggcctggtacatcggtttcctgacactcatcctttcttcatttcttgtctacctggttgagaaagacgtcccagaggtggatgcacaaggagaggagatgaaagaggagtttgagacctatgcagatgccctgtggtggggcctgatcacactggccaccattggctatggagacaagacacccaaaacgtgggaaggccgtctgattgccgccaccttttccttaattggcgtctccttttttgcccttccagcgggcatcctggggtccgggctggccctcaaggtgcaggagcaacaccgtcagaagcactttgagaaaaggaggaagccagctgctgagctcattcaggctgcctggaggtattatgctaccaaccccaacaggattgacctggtggcgacatggagattttatgaatcagtcgtctcttttcctttcttcaggaaagaacagctggaggcagcatccagccaaaagctgggtctcttggatcgggttcgcctttctaatcctcgtggtagcaatactaaaggaaagctatttacccctctgaatgtagatgccatagaagaaagtccttctaaagaaccaaagcctgttggcttaaacaataaagagcgtttccgcacggccttccgcatgaaagcctacgctttctggcagagttctgaagatgccgggacaggtgaccccatggcggaagacaggggctatgggaatgacttccccatcgaagacatgatccccaccctgaaggccgccatccgagccgtcagaattctacaattccgtctctataaaaaaaaattcaaggagactttgaggccttacgatgtgaaggatgtgattgagcagtattctgccgggcatctcgacatgctttccaggataaagtaccttcagacgagaatagatatgattttcacccctggacctccctccacgccaaaacacaagaagtctcagaaagggtcagcattcaccttcccatcccagcaatctcccaggaatgaaccatatgtagccagaccatccacatcagaaatcgaagaccaaagcatgatggggaagtttgtaaaagttgaaagacaggttcaggacatggggaagaagctggacttcctcgtggatatgcacatgcaacacatggaacggttgcaggtgcaggtcacggagtattacccaaccaagggcacctcctcgccagctgaagcagagaagaaggaggacaacaggtattccgatttgaaaaccatcatctgcaactattctgagacaggccccccggaaccaccctacagcttccaccaggtgaccattgacaaagtcagcccctatgggttttttgcacatgaccctgtgaacctgccccgagggggacccagttctggaaaggttcaggcaactcctccttcctcagcaacaacgtatgtggagaggcccacggtcctgcctatcttgactcttctcgactcccgagtgagctgccactcccaggctgacctgcagggcccctactcggaccgaatctccccccggcagagacgtagcatcacgcgagacagtgacacacctctgtccctgatgtcggtcaaccacgaggagctggagaggtctccaagtggcttcagcatctcccaggacagagatgattatgtgttcggccccaatggggggtcgagctggatgagggagaagcggtacctcgccgagggtgagacggacacagacacggaccccttcacgcccagcggctccatgcctctgtcgtccacaggggatgggatttctgattcagtatggaccccttccaataagcccatttaaaagaggtcactggctgacccctccttgtaatgtagacagactttgtatagttcacttactcttacacccgacgcttaccagcggggacaccaatggctgcatcaaatgcatgcgtgtgcgtggtggccccacccaggcaggggcttcccacagcctcttcctccccatgtcaccacaacaaagtgcttccttttcagcatggtttgcatgactttacactatataaatggttccgctaatctcttctaggatacacatttatctgctgttcttacttttaatcacgattggaccagtacagggagaaattactgatgagccatgctatttgtctgtttggttggctggtttgggttttggtttggtaagcagagaaagtagtttaagttatttctaggatcactgccctcttgtgtaaaacgctccagcaattaactgtttttgaaagcaaggaaataattttctcaacaaaaccacattgtgtatcagtggggctgcctactgagctaacattaggaaaggaatgagatagtcattgtgtctctaaaacaaagaatttaaacaaatatttaaggcaaaaccttttaaaagctctccaaaagacctcacttggcctgatgttacttagtatcatgcctcagtttccttatctgtaaaaagtggtggtaatcccaagtgtagcatttctgatgagttatgaattggcagggagaaaacacacacacacacacacacacacacacacacacacacatacacaaagttaaaatagtttccaatttatgtagccaaggacaatggaatttatcagaagtgaagtgcccctctgggcaggagctgagttcagtgcctttaaaatgaatttccaactctcatttcttcccatgatactgaagtacaaaatatccatctaaaatagaaattaaagtcaagaaggcacacagaaattttctagtccaaggacttccttttataaatgaagaatcttaggctcaggtaaagtgacatacccagagtcactcagttgtcccatagagaaccaggactcaaaagtcaggtctgcccactctccctgaccttgtttcccctcaccacaccattcttccatttatataatgcatcctagagattgtgtcaagatatatgactttgtgtcgcgtggaaagcacccagtttatccagcaggagggggatttccacttttattgcaaaacatgcttgcttgatgcaatgcatttcagatctagaaaaaaataatgcaagcaagctacatttacagatgtgtaaacaggcaaaatttccagaaccgtccaattttacttttccaaatttatggaaccaacccagattttttaaatgaaaatactaaaaccatatgtaaccgtaagacaagctaaaatgtaagcagacagcctgggaagcactgccctactgtacaggtgtgatattaagcacaagccatcctctggcctcttatgagatgttgttattctctgaaaaactttgatggaaaaggtttctgttaggcttagactgaattagctaaatgaccatgccacagtattattgtatcactcttctcacacacctaggcactggttgtggatagttgccatggtgacaatcaagataatccagatgacctaaacaaatgtctgtatgcagctgacactgctattctccctcacagtcttgtcaagagccacagtagctatggcagacatttggttgatggtttcatcatttcctaatacgagagtctggcactatgttggagagaggaatcacttcctcagagataggttcctttcaactcacatgtcaacagttactgtacaaaaagctcagaatacagtaatgattagagcttgacccctgactttaggaacttagaaccaaagcccaaagtcccaggccaagggcagacattgtgagcagcagaagggtgttttttatggagagccccataaatggatgggtgtagaccttgaagtctgagatgggaaatataccagaatgctcaatgcatcagacatgaagccccacgggcttccatttgacatgctggcaatctgaaggacaaagggcatgggttatttgggccttttccccactccttcaatatggctgaaagtgccagtggggattacaacctaagaaaccctatgccccttcctgagggcttgattattgaatcctgatcttcctggaatctttcacttgagatgatcacctgcctaacatccaacatgttactatgctcttctttatgtacatgagttactggaaaccaacaataaaggagagtgagtcatactctccacatatgcgccaattaattttttaacttacttattagtattcttgaagaacttactatcttaagtattttaccaatagatgatgcattttccagcaactcaatggagttctaccttaaagtatttaccattgatccaaaattggaggaactaccttagattcttttaataacctagaaaggattggagcttgtattatttcctaaaccataggcaggcagtctagcttccctgctggatcataagaccaggacagcagagattgggtttgtattgatcagtagtagggaagtattgattgtctaacatctagtaagttgtctttatcagtatagacatagacaaaatacatgttttatgaatgaataaataataagaacctta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cccctctgaatacttttccaaggagggggcagttcccacccccatagttcccctgagggttaagagtccaggtggtggccaagttgcaagatttggggcagccattttgccaaggatcagagatttgctgttggagaggtgaagtcggctctgtgccatcctgaaaaatcaacttagaaagataggtggacttcatcagatttgtcagtccttccttgttttaaagagaaaaatgatctctgccttgcttcagataggatatggctattttttttccttctttttctaatgtagcagtgatggaaaacaccagtctttgaagaacaaatggaggttcccagtgacatgaatccattatatttgattttggattgtattttttaacccctttttatggcatagaattctggtgccttgctccctgggtttgtctctgtgctacgagtaggctttcttcacattctggcttacaggggaacacaactattccacaagtggcctttagtgctctttataatatgatttcctgtaatttttaaactgtatgtgtaatttatattctggctctgtccaatatttgaacaactttaataggttgatttccatatatattatgcaaataattcttacctgattttttatgttctatcttaaataaatactgcaccacttattaataaatagacatttcagtgattaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:3786 -> Molecular function: GO:0005249 [voltage-gated potassium channel activity] evidence: TAS
GeneID:3786 -> Molecular function: GO:0005251 [delayed rectifier potassium channel activity] evidence: IBA
GeneID:3786 -> Molecular function: GO:0005267 [potassium channel activity] evidence: TAS
GeneID:3786 -> Biological process: GO:0006813 [potassium ion transport] evidence: TAS
GeneID:3786 -> Biological process: GO:0007268 [synaptic transmission] evidence: TAS
GeneID:3786 -> Biological process: GO:0007411 [axon guidance] evidence: TAS
GeneID:3786 -> Biological process: GO:0060081 [membrane hyperpolarization] evidence: IEA
GeneID:3786 -> Cellular component: GO:0005886 [plasma membrane] evidence: ISS
GeneID:3786 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS
GeneID:3786 -> Cellular component: GO:0008076 [voltage-gated potassium channel complex] evidence: IEA
GeneID:3786 -> Cellular component: GO:0033268 [node of Ranvier] evidence: ISS
GeneID:3786 -> Cellular component: GO:0043194 [axon initial segment] evidence: ISS
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