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2024-03-29 07:21:25, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001199252            2492 bp    mRNA    linear   PRI 14-APR-2013
DEFINITION  Homo sapiens shugoshin-like 1 (S. pombe) (SGOL1), transcript
            variant A4, mRNA.
ACCESSION   NM_001199252
VERSION     NM_001199252.1  GI:312922334
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2492)
  AUTHORS   Greenwood,T.A., Akiskal,H.S., Akiskal,K.K. and Kelsoe,J.R.
  CONSRTM   Bipolar Genome Study
  TITLE     Genome-wide association study of temperament in bipolar disorder
            reveals significant associations with three novel Loci
  JOURNAL   Biol. Psychiatry 72 (4), 303-310 (2012)
   PUBMED   22365631
REFERENCE   2  (bases 1 to 2492)
  AUTHORS   Liu,L., Zhang,N., Liu,J., Min,J., Ma,N., Liu,N., Liu,Y. and
            Zhang,H.
  TITLE     Lentivirus-mediated siRNA interference targeting SGO-1 inhibits
            human NSCLC cell growth
  JOURNAL   Tumour Biol. 33 (2), 515-521 (2012)
   PUBMED   22161216
  REMARK    GeneRIF: Lentivirus-mediated siRNA interference targeting SGO-1
            inhibits human NSCLC cell growth
REFERENCE   3  (bases 1 to 2492)
  AUTHORS   Kahyo,T., Iwaizumi,M., Shinmura,K., Matsuura,S., Nakamura,T.,
            Watanabe,Y., Yamada,H. and Sugimura,H.
  TITLE     A novel tumor-derived SGOL1 variant causes abnormal mitosis and
            unstable chromatid cohesion
  JOURNAL   Oncogene 30 (44), 4453-4463 (2011)
   PUBMED   21532624
  REMARK    GeneRIF: These results suggest that SGOL1-P1 may function as a
            negative factor to native SGOL1, and that abundant expression of
            SGOL1-P1 may be responsible for chromosomal instability.
REFERENCE   4  (bases 1 to 2492)
  AUTHORS   Kang,J., Chaudhary,J., Dong,H., Kim,S., Brautigam,C.A. and Yu,H.
  TITLE     Mitotic centromeric targeting of HP1 and its binding to Sgo1 are
            dispensable for sister-chromatid cohesion in human cells
  JOURNAL   Mol. Biol. Cell 22 (8), 1181-1190 (2011)
   PUBMED   21346195
  REMARK    GeneRIF: HP1alpha binding by INCENP or Shugoshin 1 (Sgo1) is
            dispensable for centromeric cohesion protection during mitosis of
            human cells, but might regulate yet unknown interphase functions of
            the chromosome passenger complex (CPC) or Sgo1 at the centromeres.
REFERENCE   5  (bases 1 to 2492)
  AUTHORS   Okamoto,N., Kuwahara,K., Ohta,K., Kitabatake,M., Takagi,K.,
            Mizuta,H., Kondo,E. and Sakaguchi,N.
  TITLE     Germinal center-associated nuclear protein (GANP) is involved in
            mRNA export of Shugoshin-1 required for centromere cohesion and in
            sister-chromatid exchange
  JOURNAL   Genes Cells 15 (5), 471-484 (2010)
   PUBMED   20384790
  REMARK    GeneRIF: Data show that human germinal center-associated nuclear
            protein (GANP) is critically involved in cell proliferation at the
            mitotic phase through its selective support of shugoshin-1 mRNA
            export.
REFERENCE   6  (bases 1 to 2492)
  AUTHORS   Wang,X. and Dai,W.
  TITLE     Shugoshin, a guardian for sister chromatid segregation
  JOURNAL   Exp. Cell Res. 310 (1), 1-9 (2005)
   PUBMED   16112668
  REMARK    GeneRIF: A comprehensive review of Sgo1 function in eukaryote at
            meiosis and mitosis.
            Review article
REFERENCE   7  (bases 1 to 2492)
  AUTHORS   McGuinness,B.E., Hirota,T., Kudo,N.R., Peters,J.M. and Nasmyth,K.
  TITLE     Shugoshin prevents dissociation of cohesin from centromeres during
            mitosis in vertebrate cells
  JOURNAL   PLoS Biol. 3 (3), E86 (2005)
   PUBMED   15737064
  REMARK    GeneRIF: A shugoshin-like protein associates with centromeres
            during prophase and disappears at the onset of anaphase
REFERENCE   8  (bases 1 to 2492)
  AUTHORS   Kitajima,T.S., Hauf,S., Ohsugi,M., Yamamoto,T. and Watanabe,Y.
  TITLE     Human Bub1 defines the persistent cohesion site along the mitotic
            chromosome by affecting Shugoshin localization
  JOURNAL   Curr. Biol. 15 (4), 353-359 (2005)
   PUBMED   15723797
REFERENCE   9  (bases 1 to 2492)
  AUTHORS   Tang,Z., Sun,Y., Harley,S.E., Zou,H. and Yu,H.
  TITLE     Human Bub1 protects centromeric sister-chromatid cohesion through
            Shugoshin during mitosis
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 101 (52), 18012-18017 (2004)
   PUBMED   15604152
  REMARK    GeneRIF: Bub1 protects centromeric cohesion through Shugoshin in
            mitosis
REFERENCE   10 (bases 1 to 2492)
  AUTHORS   Scanlan,M.J., Gout,I., Gordon,C.M., Williamson,B., Stockert,E.,
            Gure,A.O., Jager,D., Chen,Y.T., Mackay,A., O'Hare,M.J. and Old,L.J.
  TITLE     Humoral immunity to human breast cancer: antigen definition and
            quantitative analysis of mRNA expression
  JOURNAL   Cancer Immun. 1, 4 (2001)
   PUBMED   12747765
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DB163747.1, AB193060.1 and AB187578.1.
            
            Transcript Variant: This variant (A4) has an alternate 5' UTR exon,
            and encodes the same isoform A2, also known as isoform 1EF, as
            compared to variant A2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB193060.1 [ECO:0000332]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-105               DB163747.1         1-105
            106-2074            AB193060.1         1-1969
            2075-2492           AB187578.1         1923-2340
FEATURES             Location/Qualifiers
     source          1..2492
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p24.3"
     gene            1..2492
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /note="shugoshin-like 1 (S. pombe)"
                     /db_xref="GeneID:151648"
                     /db_xref="HGNC:25088"
                     /db_xref="MIM:609168"
     exon            1..285
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(30)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:145702873"
     variation       complement(62)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:370108487"
     variation       complement(71)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375306760"
     variation       complement(79)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140520229"
     variation       complement(86)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151299371"
     variation       complement(208)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:367619352"
     variation       complement(230)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:373672736"
     variation       complement(245)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185204088"
     misc_feature    275..277
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /note="upstream in-frame stop codon"
     variation       complement(279)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372239899"
     exon            286..434
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /inference="alignment:Splign:1.39.8"
     CDS             293..1978
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /note="isoform A2 is encoded by transcript variant A4;
                     shugoshin 1AB protein; shugoshin 1CD protein; shugoshin
                     1EF protein; shugoshin 1GH protein; shugoshin 1KL protein;
                     hSgo1; serologically defined breast cancer antigen
                     NY-BR-85"
                     /codon_start=1
                     /product="shugoshin-like 1 isoform A2"
                     /protein_id="NP_001186181.1"
                     /db_xref="GI:312922335"
                     /db_xref="CCDS:CCDS33716.1"
                     /db_xref="GeneID:151648"
                     /db_xref="HGNC:25088"
                     /db_xref="MIM:609168"
                     /translation="
MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDNNKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSSGMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSGEAKSTDNVLPRTVSVRSSLKKHCNSICQFDSLDDFETSHLAGKSFEFERVGFLDPLVNMHIPENVQHNACQWSKDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGSKPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTASVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKRALEVSPAKEAIFILYYVREFVSRFPDCRKCKLETHICLR
"
     misc_feature    293..820
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5FBB7.1);
                     Region: Necessary for interaction with PPP2CA and PPP2R1A"
     misc_feature    332..334
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine, by NEK2; propagated from
                     UniProtKB/Swiss-Prot (Q5FBB7.1); phosphorylation site"
     misc_feature    356..493
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /note="Shugoshin N-terminal coiled-coil region; Region:
                     Shugoshin_N; pfam07558"
                     /db_xref="CDD:203682"
     misc_feature    866..892
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5FBB7.1);
                     Region: D-box 1"
     misc_feature    1058..1060
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q5FBB7.1); phosphorylation site"
     misc_feature    1220..1228
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5FBB7.1);
                     Region: KEN box"
     misc_feature    1598..1600
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q5FBB7.1); phosphorylation site"
     misc_feature    1604..1630
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5FBB7.1);
                     Region: D-box 2"
     misc_feature    1661..1687
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5FBB7.1);
                     Region: D-box 3"
     misc_feature    1703..1780
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /note="Shugoshin C terminus; Region: Shugoshin_C;
                     pfam07557"
                     /db_xref="CDD:191783"
     misc_feature    1811..1813
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine, by NEK2; propagated from
                     UniProtKB/Swiss-Prot (Q5FBB7.1); phosphorylation site"
     variation       complement(322)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:143768051"
     variation       complement(354)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374022493"
     variation       complement(359)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199815268"
     variation       complement(383)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:140691683"
     variation       complement(385)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202081733"
     variation       complement(391)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113892853"
     variation       complement(398)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377471833"
     variation       complement(406)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:143576733"
     variation       complement(419)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145234403"
     variation       complement(428)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150552043"
     exon            435..631
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(453)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:192601368"
     variation       complement(466)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200787365"
     variation       complement(482)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189746950"
     variation       complement(530)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145242036"
     variation       complement(534)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201174493"
     variation       complement(582)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202028804"
     variation       complement(604)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:369840848"
     variation       complement(616)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375511922"
     variation       complement(626)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183736430"
     exon            632..708
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(657)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148317477"
     variation       complement(705)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147441982"
     exon            709..767
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /inference="alignment:Splign:1.39.8"
     exon            768..1574
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(796)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:61729306"
     variation       complement(804)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:6806241"
     variation       complement(831)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140685569"
     variation       complement(856)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367609696"
     variation       complement(867)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200607145"
     variation       complement(872)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141448850"
     variation       complement(879)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201666618"
     variation       complement(902)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:151026905"
     variation       complement(917)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145787431"
     variation       complement(927)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199568517"
     variation       complement(941)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:202142252"
     variation       complement(946)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:35175566"
     variation       complement(962)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371410180"
     variation       complement(968)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:201024235"
     variation       complement(978)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:35074792"
     variation       complement(1034)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141653863"
     variation       complement(1076)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377735470"
     variation       complement(1083)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148005116"
     variation       complement(1105)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199637337"
     variation       complement(1152)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202140002"
     variation       complement(1167)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201455258"
     variation       complement(1177)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184464880"
     variation       complement(1218)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142110258"
     variation       complement(1253)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:115863450"
     variation       complement(1257)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:9868701"
     variation       complement(1271)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:374732712"
     variation       complement(1327)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200285702"
     variation       complement(1365..1366)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:35163591"
     variation       complement(1367..1368)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:35504209"
     variation       complement(1370..1371)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:36005344"
     variation       complement(1388)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373453727"
     variation       complement(1393)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369277528"
     variation       complement(1399)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147815310"
     variation       complement(1418..1419)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:34764095"
     variation       complement(1422)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144412205"
     variation       complement(1452)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145134729"
     variation       complement(1470)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200157936"
     variation       complement(1471)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369380844"
     exon            1575..1764
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1597)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368034531"
     variation       complement(1610)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375090371"
     variation       complement(1615)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:199965073"
     variation       complement(1622)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139053195"
     variation       complement(1629)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139869512"
     variation       complement(1647)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146108565"
     variation       complement(1678)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:75326306"
     variation       complement(1711)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113607987"
     variation       complement(1735)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149344897"
     variation       complement(1736)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372402306"
     variation       complement(1752)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:181464459"
     exon            1765..1856
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1766)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:13060316"
     variation       complement(1828)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200039832"
     variation       complement(1845)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:77194360"
     exon            1857..2490
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1860)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199603756"
     variation       complement(1865)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369926768"
     variation       complement(1911)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368430426"
     variation       complement(1924)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151004231"
     variation       complement(1929)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200770059"
     variation       complement(1937)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148485165"
     variation       complement(1938)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375535687"
     variation       complement(1959)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139865348"
     variation       complement(1978..1980)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace=""
                     /replace="aag"
                     /db_xref="dbSNP:147648109"
     variation       complement(1995)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368161123"
     variation       complement(2004..2005)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace=""
                     /replace="tt"
                     /db_xref="dbSNP:200745858"
     variation       complement(2022)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374709212"
     variation       complement(2023)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370945018"
     variation       complement(2051)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:191550560"
     variation       complement(2071)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:185656328"
     variation       complement(2332)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140309229"
     variation       complement(2346)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138585609"
     variation       complement(2366)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:182471636"
     variation       complement(2392)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:189655218"
     variation       complement(2463)
                     /gene="SGOL1"
                     /gene_synonym="NY-BR-85; SGO; Sgo1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:150147188"
ORIGIN      
aatggaggagcgaggcggaaaatttcgaatgtggcggcggtagttccaggcgacggcggacggtggtacggtcctggagggcccagtgcgcggggctagccgtggctggagagcttcgaagagccttgaaatgtgaggaggaggaagatagctgttgcagaagtagtggccaaggtatcgttctggacgcgcctgcggcaggagggtcgccgcgtccacttccgccagccccacctccccccggccttcctggagtccctgaaagaggaagaagtaggttttaaggcaaaagatggccaaggaaagatgcctgaaaaagtcctttcaagatagtcttgaagacataaagaagcgaatgaaagagaaaaggaataaaaacttggcagagattggcaaacgcaggtcttttatagctgcaccatgccaaataatcaccaacacttctacactgctgaaaaattaccaagacaacaacaaaatgttagttttagctttggaaaatgaaaaatccaaagtgaaagaagcccaagatatcatcctacagctgagaaaagaatgttactatctcacatgtcagctatatgcattgaaaggaaaacttacatcacaacaaacagtagaacctgctcagaaccaggaaatatgttcctctggaatggaccccaatagtgatgacagctccagaaatttatttgtgaaggatttaccgcaaattcctcttgaagaaactgaacttccaggacaaggagaatcatttcaaatagaagatcagatacctactattcctcaagacacactgggagttgattttgattcaggtgaagctaagtctactgataatgtcttacctagaactgtatctgttcgtagcagtttaaagaaacattgtaacagtatatgtcagtttgatagcttggatgattttgaaaccagtcatttggcagggaagtcttttgaattcgaaagagttggatttttagacccactagtaaacatgcacatacctgaaaatgtacaacacaatgcttgtcaatggagcaaggaccaagttaacttatcaccaaagctgattcagccaggaacgtttactaaaacaaaagaagacattttagaatctaaatctgaacaaactaaaagtaagcaaagagatacacaagaaagaaaaagagaagagaaaagaaaagctaacaggagaaaatcaaaacgtatgtcaaaatataaagagaataaaagcgaaaataaaaaaactgttccccaaaaaaaaatgcacaaatctgtcagttccaatgatgcttacaattttaatttggaagagggtgttcatcttactcctttccgacaaaaagtgagcaatgactctaatagagaagaaaacaacgagtctgaagtgagcctctgtgaatcaagtggttcaggagatgattccgatgacctctatttgcccacttgcaagtacattcagaatcccacgagcaattcagatagaccagtcaccaggcctctagctaaaagagcactgaaatacacagatgaaaaagagacggagggttctaagccaacaaaaactcctaccactacaccacctgaaactcagcagtcacctcatcttagcctgaaggatatcaccaatgtctccttgtatcctgttgtgaaaatcagaagactttctctttctccaaaaaagaataaagcaagcccagcagtggctctgcctaaacgtaggtgcacagccagcgtgaactataaggagcccaccctcgcttcgaaactgagaagaggggacccttttacagatttgtgttttttgaattctcctattttcaagcagaaaaaggatttgagacgttctaaaaaaagagccctggaggtatcacctgccaaagaagcaatttttattttatattatgttcgagaatttgtttcgagattcccagactgtaggaaatgtaaacttgaaacccacatctgcttgaggtaaagtccacgggcttcacatccttagaaaacttttttagtccatgcattcactaatgtatgcagacctttaatagattctagctttatgtgttgggggagagatggaggggtgttgacagtctgtttcactcagcctacatacataataaaatctaagccctttaattagagatagcaactttcccagggtgaccgaggaatcagtacgtgttgaacccctcttttaagtttccttttggttgtgtcacttggagattgccttttctttcttgtaagctcagctgtgtcctcaaatatattgcattttacccagcatttccaggtgttttcaggggtcaaagtttttaagttatcttagtctttgatattgtgtaagcgaaattctccaatcccatctcctagatgatttttttttaaatcacaaaatgtgattatgcttaacagctgtttcctgtttctcttaaaataaaatccatttcctatttctcttaaaataaaatccattattcttaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:151648 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:151648 -> Biological process: GO:0000278 [mitotic cell cycle] evidence: TAS
            GeneID:151648 -> Biological process: GO:0007059 [chromosome segregation] evidence: IDA
            GeneID:151648 -> Biological process: GO:0007067 [mitosis] evidence: IEA
            GeneID:151648 -> Biological process: GO:0008608 [attachment of spindle microtubules to kinetochore] evidence: IDA
            GeneID:151648 -> Biological process: GO:0010457 [centriole-centriole cohesion] evidence: IDA
            GeneID:151648 -> Biological process: GO:0045132 [meiotic chromosome segregation] evidence: IEA
            GeneID:151648 -> Biological process: GO:0051301 [cell division] evidence: IEA
            GeneID:151648 -> Cellular component: GO:0000775 [chromosome, centromeric region] evidence: IDA
            GeneID:151648 -> Cellular component: GO:0000776 [kinetochore] evidence: IDA
            GeneID:151648 -> Cellular component: GO:0000777 [condensed chromosome kinetochore] evidence: IEA
            GeneID:151648 -> Cellular component: GO:0000779 [condensed chromosome, centromeric region] evidence: IDA
            GeneID:151648 -> Cellular component: GO:0000780 [condensed nuclear chromosome, centromeric region] evidence: IEA
            GeneID:151648 -> Cellular component: GO:0000922 [spindle pole] evidence: IDA
            GeneID:151648 -> Cellular component: GO:0005813 [centrosome] evidence: IDA
            GeneID:151648 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:151648 -> Cellular component: GO:0030892 [mitotic cohesin complex] evidence: IDA

by @meso_cacase at DBCLS
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