LOCUS       NM_001199014            2881 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens sperm-tail PG-rich repeat containing 1 (STPG1),
            transcript variant 4, mRNA.
ACCESSION   NM_001199014
VERSION     NM_001199014.1  GI:312222706
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2881)
  AUTHORS   Fujikane,R., Sanada,M., Sekiguchi,M. and Hidaka,M.
  TITLE     The identification of a novel gene, MAPO2, that is involved in the
            induction of apoptosis triggered by O(6)-methylguanine
  JOURNAL   PLoS ONE 7 (9), E44817 (2012)
   PUBMED   23028632
  REMARK    GeneRIF: MAPO2 gene product might positively contribute to the
            induction of apoptosis triggered by O-methylguanine
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BI917854.1, BC035061.1 and BC063891.1.
            
            Transcript Variant: This variant (4) has an additional exon in the
            5' region, resulting in a downstream AUG start codon, compared to
            variant 1. The resulting isoform (3) has a shorter N-terminus, as
            compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC035061.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025084, ERS025085 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-32                BI917854.1         1-32
            33-588              BC035061.1         6-561
            589-2881            BC063891.1         477-2769
FEATURES             Location/Qualifiers
     source          1..2881
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.11"
     gene            1..2881
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /note="sperm-tail PG-rich repeat containing 1"
                     /db_xref="GeneID:90529"
                     /db_xref="HGNC:28070"
     exon            1..99
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /inference="alignment:Splign:1.39.8"
     exon            100..237
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /inference="alignment:Splign:1.39.8"
     exon            238..381
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    378..380
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /note="upstream in-frame stop codon"
     exon            382..500
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /inference="alignment:Splign:1.39.8"
     exon            501..602
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /inference="alignment:Splign:1.39.8"
     CDS             588..1316
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /note="isoform 3 is encoded by transcript variant 4;
                     UPF0490 protein C1orf201; sperm-tail PG-rich
                     repeat-containing protein 1; O6-methylguanine-induced
                     apoptosis 2; O(6)-methylguanine-induced apoptosis 2"
                     /codon_start=1
                     /product="O(6)-methylguanine-induced apoptosis 2 isoform
                     3"
                     /protein_id="NP_001185943.1"
                     /db_xref="GI:312222707"
                     /db_xref="GeneID:90529"
                     /db_xref="HGNC:28070"
                     /translation="

MFPSMCARLDTIISKYPAANAYTIPSDFISKRDFSNSCSSMFQLPSFMKALKFETPAPNYYNASVSCCKQRNNVCTRAGFMSKTQRGSFAFADKGPPPGHYDINESLVKQSPNTLMSCFKSKTNRGLKLTSTGPGPGYYNPSDCTKVPKKTLFPKNPILNFSAQPSPLPPKPPFPGPGQYEIVDYLGPRKHFISSASFVSNTSRWTAAPPQPGLPGPATYKPELPGKQSFLYNEDKKWIPVL

"
     variation       589
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11538189"
     exon            603..773
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /inference="alignment:Splign:1.39.8"
     variation       624
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1142057"
     variation       647
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1064842"
     variation       698
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11538188"
     exon            774..882
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /inference="alignment:Splign:1.39.8"
     exon            883..1048
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /inference="alignment:Splign:1.39.8"
     exon            1049..1239
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /inference="alignment:Splign:1.39.8"
     exon            1240..2860
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /inference="alignment:Splign:1.39.8"
     STS             2614..2787
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /standard_name="SHGC-74407"
                     /db_xref="UniSTS:74166"
     variation       2671
                     /gene="STPG1"
                     /gene_synonym="C1orf201; MAPO2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1047696"
ORIGIN      

cgcggacggcggaaggtggactcgcgaatgttaggcctgtgggtgccatagcgaccgggaggttgggctggccagattcagctgccgggaccggaccaggtgcttaggagaacatgcagtagaacttttcatcaaacaaatggaacacgtcacagaattttgctaacatggacaactctgcacagaaaaatgaacgcactggcaaacatcccagacgtgccagtgaagtacagaaaggccaaggagcagtgaggacgcttcctctgtcctgaccgcgcctcgtccaggctgctcccagaatagttttgctgtctccttcctgcctggcaagaatgtctttactatcatctccttccttttctccgggacagcctgtttaaggttttactgctgcatatccaacacaatcctccattccttttaaatctcaagcttcagtaatcccagaatcagaaaaaaaaggattcaatagtcaagccaagagatttcctcataagaagaatgatatcccaggacctgggttctacaatgttattcaccagtcaccggtgtccaacagtgtctcattgtccaagaaaggaacttgcatgtttccctcaatgtgcgcccgattggacaccatcatttctaaataccctgcagcgaatgcatacactatcccatcggattttatttccaagagagactttagtaattcgtgttccagcatgttccagttgccaagctttatgaaagctctcaagtttgaaactcctgcaccaaactattacaatgcctctgtctcttgctgcaagcagagaaacaacgtctgtactcgagccgggtttatgtcaaaaacccaaagaggatctttcgcttttgctgataaaggacctcccccagggcattatgatatcaacgaatcccttgtgaagcagtcgccaaatacattaatgtcttgttttaaatcaaaaaccaaccgtggattaaaactgacgtcaacaggcccgggacctggttattacaaccccagtgattgcacaaaagttccaaaaaagactcttttcccgaaaaaccccatcctgaacttctctgctcagccttcgcctctgcctccgaagccacctttcccaggtcctggtcagtatgagatcgtggactacttaggcccccgcaagcatttcatctctagtgcatcattcgtgtccaataccagccggtggacagcggcgccgcctcagccaggcctgcctggcccagctacgtacaagccagagcttccaggaaagcagtccttcctctacaacgaggacaagaaatggatcccggttctgtagggatgtcacacaaggtcaaggagaactccagccaccagcccaccctgcccagcgtccccaggacattcctcaggaggagaccgatcatgagtgtggcagctgacaacttggggggtggctctaccactctggcctggcatcctagccggactgctgccattgcctttgtcttgagctggagacattgctccctggagacttcaccccagccccacagactccagtggcttcctgagcagaagggaggagtggacagagccccctggctgcttccccacgcacccatccaggctgccttccggcacgactccctgccgcagactgaagggactcctgaagcgcagacttcaaggaggatcagtccaccctgaaggtggccaagcctggaagccccacccttccctgtttcattccttcattcatttacacattcattcattccctcactcctgcctttctcatttgtccctttctgacctcactcacttacggtatgtctactgggcgaaagctacctgcaggcaggtgatgctttttccaccagtccacagcttcctttctaaagtgaccacctgtttggaaagacctctctttactccttttagacctttttctctttggagtgggagatcatcttggaatggcagtggccgggcccgggggctgcgcttttccctgactttctctgctggcgggactgaattttctcaaggcttacaggcccttccatggagtccacatggcctgtctaggcctgatagctttcgtctctctatgtggagggaaaaagaaatgtgccctagtggttttggtggaggctgcacagattcgcggtgggtggggagctgccaggctccttttctgatctcccagcaggctttgactgacgctgtttagtctttctgtacattaaccccgccagataccgagaggttacaaagcctccaaggcctgtacaactgtggcctctccagagaagtggttctcagccttgactgcacactgtaatcacctggggactttaaaaagtactgaggcctggggcccacccacaaatgctgatttaactcctccagggtggggtctgggcagtggggaggcaggagccacccaggtgattccaatgataggtgtaggttgagaagcgccaccttccagcttcctaactggctctgggaggggagctgggtgggaagttcaggaggtgggaactttgtacacgcagagcacctggagcacctacagcatggctgtggttccacactcctctgtcatttaaccttcacacatcacctcgttctgacatcaagggtgcgtcacagccacagtgaggcctcgcctgggcagagcaactctgggtgccccactgggtccctcccacaggggcaggcaagcctaatgggaacccgaggcaaaaggaaacatcagtaatacgaatcctgtctttaaaactgtgatgttttgttcaccatggattttttttttgggggggggggccttaattttaaaaatattgcattaaacttatttatcttgcttattgaaaaaaaaaaaaaaaaaaaaaa

//

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:90529 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
            GeneID:90529 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
            GeneID:90529 -> Cellular component: GO:0005737 [cytoplasm] evidence: IEA