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2020-10-26 18:54:49, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001198916            6019 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens PTPRF interacting protein, binding protein 1 (liprin
            beta 1) (PPFIBP1), transcript variant 4, mRNA.
ACCESSION   NM_001198916
VERSION     NM_001198916.1  GI:312032472
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6019)
  AUTHORS   Wei,Z., Zheng,S., Spangler,S.A., Yu,C., Hoogenraad,C.C. and
            Zhang,M.
  TITLE     Liprin-mediated large signaling complex organization revealed by
            the liprin-alpha/CASK and liprin-alpha/liprin-beta complex
            structures
  JOURNAL   Mol. Cell 43 (4), 586-598 (2011)
   PUBMED   21855798
  REMARK    GeneRIF: Liprins can mediate assembly of target proteins into large
            protein complexes capable of regulating numerous cellular
            activities.
REFERENCE   2  (bases 1 to 6019)
  AUTHORS   Takeuchi,K., Soda,M., Togashi,Y., Sugawara,E., Hatano,S., Asaka,R.,
            Okumura,S., Nakagawa,K., Mano,H. and Ishikawa,Y.
  TITLE     Pulmonary inflammatory myofibroblastic tumor expressing a novel
            fusion, PPFIBP1-ALK: reappraisal of anti-ALK immunohistochemistry
            as a tool for novel ALK fusion identification
  JOURNAL   Clin. Cancer Res. 17 (10), 3341-3348 (2011)
   PUBMED   21430068
  REMARK    GeneRIF: Novel ALK fusions are being identified in various tumors
            in addition to inflammatory myofibroblastic tumor.
REFERENCE   3  (bases 1 to 6019)
  AUTHORS   Norrmen,C., Vandevelde,W., Ny,A., Saharinen,P., Gentile,M.,
            Haraldsen,G., Puolakkainen,P., Lukanidin,E., Dewerchin,M.,
            Alitalo,K. and Petrova,T.V.
  TITLE     Liprin (beta)1 is highly expressed in lymphatic vasculature and is
            important for lymphatic vessel integrity
  JOURNAL   Blood 115 (4), 906-909 (2010)
   PUBMED   19965622
  REMARK    GeneRIF: liprin beta1, a member of the family of LAR transmembrane
            tyrosine phosphatase-interacting proteins, as highly expressed in
            intestinal lymphatic endothelial cells in vitro and lymphatic
            vasculature in vivo
REFERENCE   4  (bases 1 to 6019)
  AUTHORS   Jin,J., Smith,F.D., Stark,C., Wells,C.D., Fawcett,J.P.,
            Kulkarni,S., Metalnikov,P., O'Donnell,P., Taylor,P., Taylor,L.,
            Zougman,A., Woodgett,J.R., Langeberg,L.K., Scott,J.D. and Pawson,T.
  TITLE     Proteomic, functional, and domain-based analysis of in vivo 14-3-3
            binding proteins involved in cytoskeletal regulation and cellular
            organization
  JOURNAL   Curr. Biol. 14 (16), 1436-1450 (2004)
   PUBMED   15324660
REFERENCE   5  (bases 1 to 6019)
  AUTHORS   Kriajevska,M., Fischer-Larsen,M., Moertz,E., Vorm,O.,
            Tulchinsky,E., Grigorian,M., Ambartsumian,N. and Lukanidin,E.
  TITLE     Liprin beta 1, a member of the family of LAR transmembrane tyrosine
            phosphatase-interacting proteins, is a new target for the
            metastasis-associated protein S100A4 (Mts1)
  JOURNAL   J. Biol. Chem. 277 (7), 5229-5235 (2002)
   PUBMED   11836260
  REMARK    GeneRIF: new molecular target of the S100A4 protein, liprin beta1
REFERENCE   6  (bases 1 to 6019)
  AUTHORS   Serra-Pages,C., Medley,Q.G., Tang,M., Hart,A. and Streuli,M.
  TITLE     Liprins, a family of LAR transmembrane protein-tyrosine
            phosphatase-interacting proteins
  JOURNAL   J. Biol. Chem. 273 (25), 15611-15620 (1998)
   PUBMED   9624153
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BQ777042.1, AK314350.1,
            AC009509.7, AB033056.2 and CA442440.1.
            
            Summary: The protein encoded by this gene is a member of the LAR
            protein-tyrosine phosphatase-interacting protein (liprin) family.
            Liprins interact with members of LAR family of transmembrane
            protein tyrosine phosphatases, which are known to be important for
            axon guidance and mammary gland development. It has been proposed
            that liprins are multivalent proteins that form complex structures
            and act as scaffolds for the recruitment and anchoring of LAR
            family of tyrosine phosphatases. This protein was found to interact
            with S100A4, a calcium-binding protein related to tumor
            invasiveness and metastasis. In vitro experiment demonstrated that
            the interaction inhibited the phosphorylation of this protein by
            protein kinase C and protein kinase CK2. Alternatively spliced
            transcript variants encoding distinct isoforms have been reported.
            [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (4) lacks an alternate in-frame
            exon compared to variant 2. The resulting isoform (4) has the same
            N- and C-termini but is shorter compared to isoform 2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK314350.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025082 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-112               BQ777042.1         11-122
            113-619             AK314350.1         1-507
            620-620             AC009509.7         48992-48992
            621-3320            AK314350.1         509-3208
            3321-5572           AB033056.2         3039-5290
            5573-6019           CA442440.1         1-447               c
FEATURES             Location/Qualifiers
     source          1..6019
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12p12.1"
     gene            1..6019
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="PTPRF interacting protein, binding protein 1
                     (liprin beta 1)"
                     /db_xref="GeneID:8496"
                     /db_xref="HGNC:9249"
                     /db_xref="MIM:603141"
     exon            1..254
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       43
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2289710"
     variation       85
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372353307"
     variation       212
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:12314684"
     variation       250
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374737096"
     variation       251
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:147297613"
     exon            255..342
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       283
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114441949"
     variation       330
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:4448724"
     misc_feature    336..338
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="upstream in-frame stop codon"
     exon            343..441
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       347
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201771402"
     variation       374
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:111594968"
     CDS             378..3320
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="isoform 4 is encoded by transcript variant 4;
                     liprin-beta 1; liprin related protein; protein-tyrosine
                     phosphatase receptor-type f polypeptide-interacting
                     protein-binding protein 1; liprin-beta-1;
                     PTPRF-interacting protein-binding protein 1; protein
                     tyrosine phosphatase receptor type f
                     polypeptide-interacting protein-binding protein 1"
                     /codon_start=1
                     /product="liprin-beta-1 isoform 4"
                     /protein_id="NP_001185845.1"
                     /db_xref="GI:312032473"
                     /db_xref="CCDS:CCDS55813.1"
                     /db_xref="GeneID:8496"
                     /db_xref="HGNC:9249"
                     /db_xref="MIM:603141"
                     /translation="
MMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTAETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKLNATEEMLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
"
     misc_feature    2214..2408
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="Sterile alpha motif; Region: SAM; smart00454"
                     /db_xref="CDD:197735"
     misc_feature    2214..2405
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="SAM domain of liprin-beta1,2 proteins repeat 1;
                     Region: SAM_liprin-beta1,2_repeat1; cd09563"
                     /db_xref="CDD:188962"
     misc_feature    2436..2624
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="SAM (Sterile alpha motif ); Region:
                     SAM_superfamily; cl15755"
                     /db_xref="CDD:210155"
     misc_feature    2442..>2546
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="Sterile alpha motif; Region: SAM; smart00454"
                     /db_xref="CDD:197735"
     misc_feature    2691..2906
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="SAM domain of liprin-beta proteins repeat 3;
                     Region: SAM_liprin-beta1,2_repeat3; cd09569"
                     /db_xref="CDD:188968"
     misc_feature    2703..2906
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="SAM domain (Sterile alpha motif); Region: SAM_2;
                     pfam07647"
                     /db_xref="CDD:203706"
     exon            442..647
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       466
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2881468"
     variation       485
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373361507"
     variation       525
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200244641"
     variation       544
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148953958"
     variation       570
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143657387"
     variation       614
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111340172"
     variation       619
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148076093"
     variation       620
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2075378"
     variation       629
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:17854603"
     exon            648..734
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       656
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:373440206"
     variation       661
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:73294067"
     variation       665
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:370021875"
     variation       672
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138904548"
     variation       680
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374249871"
     variation       681
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373923026"
     variation       700
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142823290"
     variation       715
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:147402814"
     variation       724
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199985476"
     variation       726
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139120224"
     variation       730
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201234208"
     exon            735..848
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       735
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:148602928"
     variation       739
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144532770"
     variation       740
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146644142"
     variation       741
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140176051"
     variation       780
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:143847599"
     variation       809
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:376729598"
     variation       812
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151288073"
     variation       819
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2194816"
     variation       828
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369134316"
     variation       838
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200914061"
     variation       842
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:73294079"
     exon            849..980
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       881
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145205395"
     variation       909
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374026427"
     variation       948
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377169543"
     variation       951
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:186690420"
     variation       960
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370323116"
     variation       969
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142355778"
     exon            981..1073
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1000
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202028953"
     exon            1074..1188
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1116
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:375385877"
     variation       1120
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:369414467"
     variation       1142
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146333349"
     variation       1151
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371497886"
     exon            1189..1250
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1191
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138974239"
     variation       1209
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376597954"
     exon            1251..1326
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1273
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370141265"
     variation       1295
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61748361"
     variation       1309
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142893025"
     exon            1327..1481
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1336
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143554172"
     variation       1352
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:185263684"
     variation       1392
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:148024203"
     variation       1447
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371077704"
     exon            1482..1597
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1502
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141690857"
     variation       1557
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200687061"
     variation       1570
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:150528906"
     exon            1598..1654
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1626
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113710428"
     variation       1632
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200945345"
     variation       1641
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35670331"
     variation       1645
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:76499984"
     exon            1655..1715
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1657
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:377752142"
     variation       1660
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:371336714"
     variation       1701
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374468566"
     exon            1716..1745
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     exon            1746..1917
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1754
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35150305"
     variation       1756
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372834652"
     variation       1757
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:146181524"
     variation       1765
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:375725857"
     variation       1769
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202174851"
     variation       1778
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140182450"
     variation       1837
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:201179220"
     variation       1840
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376929898"
     variation       1864
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376591163"
     variation       1874
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:143859582"
     variation       1878
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200910244"
     variation       1897
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373605140"
     exon            1918..2068
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1956
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201187783"
     variation       1972
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200486013"
     variation       1993
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142910651"
     variation       1994
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:187660139"
     variation       2012
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370509537"
     exon            2069..2197
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       2069
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61739753"
     variation       2123
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368610595"
     variation       2152
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372542352"
     variation       2161
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:377120565"
     variation       2171
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201006068"
     variation       2173
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369476664"
     variation       2175
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:151071761"
     variation       2176
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142422262"
     variation       2180
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:372089803"
     exon            2198..2348
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       2206
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200645200"
     variation       2273
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:35291896"
     variation       2314
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201195756"
     variation       2321
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113931583"
     variation       2323
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147864879"
     variation       2336
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367649651"
     exon            2349..2460
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       2349
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373637167"
     variation       2355
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200119939"
     variation       2369
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141451946"
     variation       2374
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150367272"
     variation       2377
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367618122"
     variation       2415
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138046370"
     variation       2432..2433
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:34022369"
     variation       2447
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372355893"
     variation       2450
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149093315"
     exon            2461..2549
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       2500
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202011004"
     variation       2541
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:143124134"
     variation       2547
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:202193926"
     exon            2550..2672
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       2652
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138624973"
     variation       2656..2657
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:34220354"
     variation       2669
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373465725"
     exon            2673..2798
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       2682
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376329180"
     variation       2684
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61917497"
     variation       2702
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:138941072"
     variation       2715
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146185523"
     variation       2734
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369668351"
     variation       2748
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:137864595"
     variation       2753
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373149305"
     exon            2799..2987
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       2871
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373264878"
     variation       2872
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201325210"
     variation       2903
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61730962"
     variation       2910
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:192927833"
     variation       2914
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:147160498"
     variation       2923
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150045915"
     exon            2988..3167
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       3017
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201810502"
     variation       3055
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368511222"
     variation       3069
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140823525"
     variation       3081
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200511262"
     variation       3121
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113985648"
     variation       3129
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144681794"
     variation       3130
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61757741"
     variation       3157
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201126471"
     exon            3168..3233
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       3232
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375535195"
     variation       3233
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369788968"
     exon            3234..6002
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       3237
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:142730346"
     variation       3266
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370440817"
     variation       3277
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371325602"
     variation       3294
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199801908"
     variation       3314
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:55923847"
     variation       3323
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374114077"
     variation       3336
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:367971027"
     variation       3367
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371421286"
     variation       3387
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372609088"
     variation       3406
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:144504690"
     variation       3429
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3764010"
     variation       3443
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148395830"
     variation       3470
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183102078"
     variation       3623
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:7309005"
     variation       3732
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:56856599"
     variation       3796
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368935895"
     variation       3896
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142526071"
     variation       3897
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187768966"
     variation       3920
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:16932296"
     variation       4034
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:76599957"
     STS             4184..5839
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /standard_name="L18426"
                     /db_xref="UniSTS:34648"
     variation       4235
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11049095"
     variation       4241
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111818593"
     variation       4305
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:193300307"
     variation       4335
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185140996"
     variation       4435..4436
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:200249833"
     variation       4445
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:78218603"
     variation       4452
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:190382759"
     variation       4477
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151006610"
     STS             4557..5597
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /standard_name="L18506"
                     /db_xref="UniSTS:54024"
     variation       4579
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:114845811"
     variation       4597
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:115719991"
     STS             4716..5597
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /standard_name="L18506"
                     /db_xref="UniSTS:54024"
     variation       4722
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139994391"
     variation       4725
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143369313"
     variation       4967
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:74074224"
     variation       4982
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146711132"
     variation       4999
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140345118"
     variation       5009
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368687919"
     variation       5046
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:74074225"
     variation       5049
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:192629982"
     variation       5074
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:150209760"
     variation       5278
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:184250045"
     variation       5279
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:188143172"
     variation       5296
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116652155"
     variation       5417
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:74462176"
     variation       5501
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:180903040"
     variation       5540
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373193073"
     variation       5557..5558
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:201424178"
     variation       5558..5560
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:57935514"
     variation       5559
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:74663411"
     variation       5573
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201472128"
     variation       5577
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145772097"
     variation       5591
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:148923051"
     variation       5593
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186290546"
     variation       5594
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190370936"
     variation       5625
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:12315453"
     variation       5669
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376952306"
     STS             5733..5835
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /standard_name="D11S3114"
                     /db_xref="UniSTS:152207"
     variation       5735
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:369436228"
     variation       5806
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143674494"
     variation       5810
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:182557126"
     variation       5838
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:186682610"
     variation       5846
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148164406"
     variation       5848
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144049521"
     variation       5849
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146907125"
     variation       5853
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369225674"
     polyA_signal    5977..5982
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
     polyA_site      6002
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
ORIGIN      
gattcctgcagggagggaggagagaagggcggcagtgggagggggaggtacctggaactgggagtgatgtcagctcccagctcggtgcctgcccggattcctgacatggtgtagtgcaggcagggtggggaaaggacggggaaggactcgtgtgctgcgagctggcggccgggccggagtgctggggctttgaactccgagaggaggtggaccagaacttttggaactagtgccggcggctctccaccccccagtataaaagaacgtgtggatcactttgctgagtacatccaagatttgaagaactgaaataaatcagctttaaacctgctttttaaaaatatctgggttggaatttgcccctgacaaataataaaatgatgagtgatgcaagtgacatgttggctgcagcgttggagcagatggatggtatcatagcaggttctaaggctctggaatattccaatgggatttttgattgccaatctcccacctctccattcatgggaagtttgcgagctctgcaccttgtggaagacctgcgtggattgttagagatgatggaaacagatgagaaagaaggcttgagatgccagatcccagattcaacagcagaaacgcttgttgaatggcttcagagtcaaatgacaaatggacacctaccagggaacggagatgtgtatcaagaaaggctggcacgtttagaaaatgataaagaatccctcgttcttcaggtaagtgtgttaacagaccaggtggaggctcagggagagaagattcgagatttggagttttgtcttgaagagcacagagagaagttgaatgccacagaagaaatgctgcagcaggagcttctaagtaggacatccttagaaactcagaagttggatctgatggctgaaatatctaacttgaagttgaaactgacagctgtagagaaggacagattggattatgaagataagttcagagacacagaggggctgattcaggagatcaatgatttgaggttaaaagttagtgaaatggacagtgagagacttcagtatgaaaaaaagcttaaatcaaccaaagatgaactggcatctttaaaagaacaactagaagaaaaggaatctgaagtaaaaaggctacaagaaaaattggtttgcaagatgaaaggagaaggggttgaaattgttgatagagacatcgaagtacaaaaaatgaaaaaagctgtggagtccttgatggcagcaaatgaagaaaaggatcggaaaatagaagatcttcgacagtgcctgaacaggtacaagaaaatgcaagacacggtggtactggcccaaggcaaagatggagaatatgaagagctgctcaattccagttccatctcctctttgctggatgcacagggtttcagtgatctggagaaaagtccatcacccactccagtaatgggatctcccagttgtgacccatttaacacaagtgttcccgaagagttccatactaccatcttgcaagtttccatcccttcattattgccagcaactgtaagcatggaaacttctgaaaaatcaaagttgactcctaagccagagacttcatttgaagaaaatgatggaaacataatccttggtgccactgttgatacccaactgtgtgataaacttttaacttcaagtctgcagaagtccagcagcctgggcaatctgaagaaagagacatctgatggggaaaaggaaactattcagaagacttcagaggacagagctccggcagaaagcaggccatttgggacccttcctcccaggcccccagggcaggacacctccatggatgacaaccccttcggcactcgaaaagtcagatcttcctttggccggggcttttttaaaatcaaaagtaacaagagaacagcaagtgcaccaaacttagctgaaacagaaaaagagacagcagagcacctagatctggctggtgcttcttctcggccaaaagattcacagaggaacagtcccttccagataccgcctccatctccagattccaaaaagaaatccagaggtatcatgaaactctttggaaaacttaggagaagtcaatcaactacattcaacccagatgacatgtctgagcctgaattcaaaagaggagggacaagggcaaccgcggggccccgattaggttggtctcgagacttgggacagtctaacagtgacttggatatgccatttgccaagtggaccaaggagcaggtttgcaattggctgatggaacagggcttgggctcgtacctgaattctggcaagcactggattgcatctggccaaacgcttttgcaggcttctcaacaagatctagagaaggaacttggaatcaagcattcacttcatcgaaagaaactccagctagcactccaagccctgggatctgaagaagaaaccaatcatgggaagctggatttcaactgggtcactagatggttggatgacattggcctccctcaatataagacccagtttgatgaaggacgggttgatggtcgaatgctacattacatgactgttgatgacttactgtctctgaaggttgtaagtgtgctacaccatctcagtatcaaaagggccatccaggtcctgaggatcaataactttgaaccaaactgtctacggaggcggccatctgatgagaataccatcgccccatcagaagttcagaagtggactaaccatcgagtgatggagtggctgcgctccgtggacttggcagaatatgcgcccaatctcagaggcagtggtgtccatggtgggctcatggttctagagcctcgttttaacgtagaaacaatggctcagttattgaacatcccacccaataagactttgctgcgaagacatttggccactcatttcaaccttctgattggggctgaggcacagcaccagaagcgagatgccatggagctgccggattatgtacttctaacagctactgccaaagtgaagccaaagaaacttgcctttagcaattttgggaatttgagaaagaagaaacaggaagatggtgaagaatatgtttgtccaatggaattgggacaggcatcaggaagtgcatctaagaaaggatttaaacctggtttggatatgcgcctgtatgaggaagatgatttggaccggttagagcagatggaagattcagaagggacagtgagacagataggtgcattctctgaaggcatcaacaatctgacgcacatgttaaaagaagatgacatgtttaaagattttgctgcccgttcccccagtgccagcattacagatgaagactcaaacgtttgaccgtagcacctggatgaacattaggagtgcttagtcttttttctacttgcttttccaaacactcacagtatatacaacaggcagcggattgtctattgtttgttgttccaacttctgctgtcgagaagtttaaacagaaagcaggagtaatgtgccgattctgaagttgccacaaaaaataagacactggtgaatgagagtataattgtttttcttctatttaatgtaaaaatctgtgatatattatatttaaagtgttgcatttaagatgagtattttaccagagtgtttccattcatatccgcggtatggaggatttgaggaacagtaaccaggatgtgaatgattttgttacatcagtgttcactgtagccacctaagtaggacattatatgatttcagaatcaatatgtggaacttctttaagcattcagtgtgcccactaaatgccagccacacctccacttgcctcttattgtcttatttttatatatttttctaaatatatgtatatatacagtacatagaaaatagaacttttattttgtgacctaaggacgatggtgaaaagatcacgttttcaaaacaatctggtgatcagaatgttcatataccagctggtttctgaagaggtcagaatgatctttctccatactgacttttaacaatgttgatcattgaggctaaattaatatatatgaaatattcctttttgatgacaccacaaaattgttgaacagtttaagaatttcaaccttaatcttggatccctttacctcatatggaagaacttgagggacattagtatacttttttttaagatggagtcttgctctgtcacccaggttggagtgccatggcatgatcttggctcactgcaacctccacctcctgggtcaagccattctgcttcagccccaagtaggtgggactccaggcatgcaccaccatgcctggctaatttttgcatttttagtagagacagggtttcaccatattggccaggctgggactcgaactcctgaccttgtgatctgcccgcctcagcctcccaaagtactgggattataggcatgagccaccacgcccagcctgttatttttttattattattgtttttttttagtgacagagtctcattctgttgcccatgctggagtgcagtggcgtgatcatagctcactgcagccttgaattcctaggctccagtgatcctctcacctcagcttccctaatagctaggattacaggtgtgtggcctcccaccccaccccacccttcacacctggctgatttttcaaaaagtttttttgtagaaacagggtctcaccatgttgtccagcctggtctcaaactcctgtcctcaagtgatcctcccacctcagcctttcaaagtgctggaattacaggtgtgagccactctgcctggcctaccactaacttgaatacattcagaatcacctcctctccccaaaatttgtagaaatagtttttgaggaagccaaaagcaaagcagaaacctttacagtattgtttcttttctctttgttaactgtgtcattacagcaaaatactagcagtctgcctaaacatgttcattgtacatttctcaggctatcaatgaatggaggtttttaaaaagttgaatatttgtctgaacattttatttcaaagttcaaaaaaacagaggctgcaaaattcattttataatggctattttgtgacgataagatgtagttcatgtttttctgtagcactgggcccaaatattctttgtaaagaaaatcgctgcagcaaaaactgttactgtgtttattatatttgtagaagtattagaaaaatattctattttttattcagtgctgcgtaattacccatggtagccaaccctacaaaagacaggttttcacaaattgaggtggaggtgggcggttcagtatctgccactggacttgattataaactgtatttgaatatcagtggtattatcttttaagttgtcagcaagttaccaaggtattcattaaagaacttgtaatatcaaattactatttattcataacaattgatttgatgctaataataattttctttaaactctaccattcattatgtggtaactgtattgaacttactttatttggattttattttaatgtgactagatgtcaccacttcaaaaaatcaatttgttcttagaacctggttgaaaataccaggaaactgttacagacgccattttttttttttttgagacggagtcttgctctgttgcccaggctggagtgcagtggcacaatctcagctcactgcaagctccgcctcctgggttcacgccattctcccacctcagcttcccaagcagctgggactacaggtacctgccaccacgcctggctaattttgtttttgtatttttagtagagacggggtttcaccgtgttagccaggaaggtctcaatctcctgacctcgtgaatcgcccccctcggtctcccaaagtgctgggattacaggcgtgagccaccatgcccggcccaaatattttttattcaggatggtataacctaactgataataggtaataaggttaaatttttttatgacgtattttatttacaaatatcatacactgctggtgttaccatatgaaaggaaataaagtcaattgataattgcctcaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:8496 -> Biological process: GO:0007155 [cell adhesion] evidence: TAS
            GeneID:8496 -> Cellular component: GO:0005886 [plasma membrane] evidence: NAS

by @meso_cacase at DBCLS
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