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2020-10-24 06:39:02, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001198915            5807 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens PTPRF interacting protein, binding protein 1 (liprin
            beta 1) (PPFIBP1), transcript variant 3, mRNA.
ACCESSION   NM_001198915
VERSION     NM_001198915.1  GI:312032470
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5807)
  AUTHORS   Wei,Z., Zheng,S., Spangler,S.A., Yu,C., Hoogenraad,C.C. and
            Zhang,M.
  TITLE     Liprin-mediated large signaling complex organization revealed by
            the liprin-alpha/CASK and liprin-alpha/liprin-beta complex
            structures
  JOURNAL   Mol. Cell 43 (4), 586-598 (2011)
   PUBMED   21855798
  REMARK    GeneRIF: Liprins can mediate assembly of target proteins into large
            protein complexes capable of regulating numerous cellular
            activities.
REFERENCE   2  (bases 1 to 5807)
  AUTHORS   Takeuchi,K., Soda,M., Togashi,Y., Sugawara,E., Hatano,S., Asaka,R.,
            Okumura,S., Nakagawa,K., Mano,H. and Ishikawa,Y.
  TITLE     Pulmonary inflammatory myofibroblastic tumor expressing a novel
            fusion, PPFIBP1-ALK: reappraisal of anti-ALK immunohistochemistry
            as a tool for novel ALK fusion identification
  JOURNAL   Clin. Cancer Res. 17 (10), 3341-3348 (2011)
   PUBMED   21430068
  REMARK    GeneRIF: Novel ALK fusions are being identified in various tumors
            in addition to inflammatory myofibroblastic tumor.
REFERENCE   3  (bases 1 to 5807)
  AUTHORS   Norrmen,C., Vandevelde,W., Ny,A., Saharinen,P., Gentile,M.,
            Haraldsen,G., Puolakkainen,P., Lukanidin,E., Dewerchin,M.,
            Alitalo,K. and Petrova,T.V.
  TITLE     Liprin (beta)1 is highly expressed in lymphatic vasculature and is
            important for lymphatic vessel integrity
  JOURNAL   Blood 115 (4), 906-909 (2010)
   PUBMED   19965622
  REMARK    GeneRIF: liprin beta1, a member of the family of LAR transmembrane
            tyrosine phosphatase-interacting proteins, as highly expressed in
            intestinal lymphatic endothelial cells in vitro and lymphatic
            vasculature in vivo
REFERENCE   4  (bases 1 to 5807)
  AUTHORS   Jin,J., Smith,F.D., Stark,C., Wells,C.D., Fawcett,J.P.,
            Kulkarni,S., Metalnikov,P., O'Donnell,P., Taylor,P., Taylor,L.,
            Zougman,A., Woodgett,J.R., Langeberg,L.K., Scott,J.D. and Pawson,T.
  TITLE     Proteomic, functional, and domain-based analysis of in vivo 14-3-3
            binding proteins involved in cytoskeletal regulation and cellular
            organization
  JOURNAL   Curr. Biol. 14 (16), 1436-1450 (2004)
   PUBMED   15324660
REFERENCE   5  (bases 1 to 5807)
  AUTHORS   Kriajevska,M., Fischer-Larsen,M., Moertz,E., Vorm,O.,
            Tulchinsky,E., Grigorian,M., Ambartsumian,N. and Lukanidin,E.
  TITLE     Liprin beta 1, a member of the family of LAR transmembrane tyrosine
            phosphatase-interacting proteins, is a new target for the
            metastasis-associated protein S100A4 (Mts1)
  JOURNAL   J. Biol. Chem. 277 (7), 5229-5235 (2002)
   PUBMED   11836260
  REMARK    GeneRIF: new molecular target of the S100A4 protein, liprin beta1
REFERENCE   6  (bases 1 to 5807)
  AUTHORS   Serra-Pages,C., Medley,Q.G., Tang,M., Hart,A. and Streuli,M.
  TITLE     Liprins, a family of LAR transmembrane protein-tyrosine
            phosphatase-interacting proteins
  JOURNAL   J. Biol. Chem. 273 (25), 15611-15620 (1998)
   PUBMED   9624153
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BQ777042.1, AB033056.2,
            AC087257.13 and CA442440.1.
            
            Summary: The protein encoded by this gene is a member of the LAR
            protein-tyrosine phosphatase-interacting protein (liprin) family.
            Liprins interact with members of LAR family of transmembrane
            protein tyrosine phosphatases, which are known to be important for
            axon guidance and mammary gland development. It has been proposed
            that liprins are multivalent proteins that form complex structures
            and act as scaffolds for the recruitment and anchoring of LAR
            family of tyrosine phosphatases. This protein was found to interact
            with S100A4, a calcium-binding protein related to tumor
            invasiveness and metastasis. In vitro experiment demonstrated that
            the interaction inhibited the phosphorylation of this protein by
            protein kinase C and protein kinase CK2. Alternatively spliced
            transcript variants encoding distinct isoforms have been reported.
            [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (3) differs in the 5' UTR and
            coding sequence compared to variant 2. The resulting isoform (3) is
            shorter at the N-terminus compared to isoform 2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB033056.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025082, ERS025083 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-70                BQ777042.1         11-80
            71-329              AB033056.2         1-259
            330-330             AC087257.13        145419-145419
            331-5360            AB033056.2         261-5290
            5361-5807           CA442440.1         1-447               c
FEATURES             Location/Qualifiers
     source          1..5807
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12p12.1"
     gene            1..5807
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="PTPRF interacting protein, binding protein 1
                     (liprin beta 1)"
                     /db_xref="GeneID:8496"
                     /db_xref="HGNC:9249"
                     /db_xref="MIM:603141"
     exon            1..254
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       43
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2289710"
     variation       85
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372353307"
     variation       212
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:12314684"
     variation       250
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374737096"
     variation       251
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:147297613"
     exon            255..342
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       283
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114441949"
     misc_feature    307..309
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="upstream in-frame stop codon"
     variation       330
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:4448724"
     exon            343..429
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       351
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:373440206"
     variation       356
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:73294067"
     variation       360
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:370021875"
     variation       367
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138904548"
     variation       375
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374249871"
     variation       376
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373923026"
     variation       395
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142823290"
     variation       410
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:147402814"
     variation       419
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199985476"
     variation       421
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139120224"
     variation       425
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201234208"
     exon            430..543
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       430
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:148602928"
     variation       434
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144532770"
     variation       435
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146644142"
     variation       436
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140176051"
     variation       475
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:143847599"
     variation       504
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:376729598"
     variation       507
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151288073"
     variation       514
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2194816"
     variation       523
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369134316"
     CDS             532..3108
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="isoform 3 is encoded by transcript variant 3;
                     liprin-beta 1; liprin related protein; protein-tyrosine
                     phosphatase receptor-type f polypeptide-interacting
                     protein-binding protein 1; liprin-beta-1;
                     PTPRF-interacting protein-binding protein 1; protein
                     tyrosine phosphatase receptor type f
                     polypeptide-interacting protein-binding protein 1"
                     /codon_start=1
                     /product="liprin-beta-1 isoform 3"
                     /protein_id="NP_001185844.1"
                     /db_xref="GI:312032471"
                     /db_xref="CCDS:CCDS55814.1"
                     /db_xref="GeneID:8496"
                     /db_xref="HGNC:9249"
                     /db_xref="MIM:603141"
                     /translation="
MLQQELLSRTSLETQKLDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSSMKIKVGQMQYEKQRMEQKWESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEFHTTILQVSIPSLLPATVSMETSEKSKLTPKPETSFEENDGNIILGATVDTQLCDKLLTSSLQKSSSLGNLKKETSDGEKETIQKTSEDRAPAESRPFGTLPPRPPGQDTSMDDNPFGTRKVRSSFGRGFFKIKSNKRTASAPNLAETEKETAEHLDLAGASSRPKDSQRNSPFQIPPPSPDSKKKSRGIMKLFGKLRRSQSTTFNPDDMSEPEFKRGGTRATAGPRLGWSRDLGQSNSDLDMPFAKWTKEQVCNWLMEQGLGSYLNSGKHWIASGQTLLQASQQDLEKELGIKHSLHRKKLQLALQALGSEEETNHGKLDFNWVTRWLDDIGLPQYKTQFDEGRVDGRMLHYMTVDDLLSLKVVSVLHHLSIKRAIQVLRINNFEPNCLRRRPSDENTIAPSEVQKWTNHRVMEWLRSVDLAEYAPNLRGSGVHGGLMVLEPRFNVETMAQLLNIPPNKTLLRRHLATHFNLLIGAEAQHQKRDAMELPDYVLLTATAKVKPKKLAFSNFGNLRKKKQEDGEEYVCPMELGQASGSASKKGFKPGLDMRLYEEDDLDRLEQMEDSEGTVRQIGAFSEGINNLTHMLKEDDMFKDFAARSPSASITDEDSNV
"
     misc_feature    2002..2196
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="Sterile alpha motif; Region: SAM; smart00454"
                     /db_xref="CDD:197735"
     misc_feature    2002..2193
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="SAM domain of liprin-beta1,2 proteins repeat 1;
                     Region: SAM_liprin-beta1,2_repeat1; cd09563"
                     /db_xref="CDD:188962"
     misc_feature    2224..2412
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="SAM (Sterile alpha motif ); Region:
                     SAM_superfamily; cl15755"
                     /db_xref="CDD:210155"
     misc_feature    2230..>2334
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="Sterile alpha motif; Region: SAM; smart00454"
                     /db_xref="CDD:197735"
     misc_feature    2479..2694
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="SAM domain of liprin-beta proteins repeat 3;
                     Region: SAM_liprin-beta1,2_repeat3; cd09569"
                     /db_xref="CDD:188968"
     misc_feature    2491..2694
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /note="SAM domain (Sterile alpha motif); Region: SAM_2;
                     pfam07647"
                     /db_xref="CDD:203706"
     variation       533
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200914061"
     variation       537
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:73294079"
     exon            544..675
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       576
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145205395"
     variation       604
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374026427"
     variation       643
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377169543"
     variation       646
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:186690420"
     variation       655
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:370323116"
     variation       664
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142355778"
     exon            676..768
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       695
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202028953"
     exon            769..861
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       792
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145263806"
     variation       795
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200359000"
     variation       832
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:181574182"
     exon            862..976
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       904
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:375385877"
     variation       908
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:369414467"
     variation       930
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146333349"
     variation       939
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371497886"
     exon            977..1038
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       979
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138974239"
     variation       997
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376597954"
     exon            1039..1114
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1061
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370141265"
     variation       1083
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61748361"
     variation       1097
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142893025"
     exon            1115..1269
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1124
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143554172"
     variation       1140
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:185263684"
     variation       1180
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:148024203"
     variation       1235
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371077704"
     exon            1270..1385
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1290
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141690857"
     variation       1345
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200687061"
     variation       1358
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:150528906"
     exon            1386..1442
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1414
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113710428"
     variation       1420
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200945345"
     variation       1429
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35670331"
     variation       1433
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:76499984"
     exon            1443..1503
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1445
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:377752142"
     variation       1448
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:371336714"
     variation       1489
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374468566"
     exon            1504..1533
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     exon            1534..1705
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1542
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35150305"
     variation       1544
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372834652"
     variation       1545
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:146181524"
     variation       1553
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:375725857"
     variation       1557
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202174851"
     variation       1566
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140182450"
     variation       1625
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:201179220"
     variation       1628
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376929898"
     variation       1652
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376591163"
     variation       1662
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:143859582"
     variation       1666
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200910244"
     variation       1685
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373605140"
     exon            1706..1856
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1744
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201187783"
     variation       1760
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200486013"
     variation       1781
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142910651"
     variation       1782
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:187660139"
     variation       1800
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370509537"
     exon            1857..1985
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1857
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61739753"
     variation       1911
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368610595"
     variation       1940
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372542352"
     variation       1949
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:377120565"
     variation       1959
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201006068"
     variation       1961
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369476664"
     variation       1963
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:151071761"
     variation       1964
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142422262"
     variation       1968
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:372089803"
     exon            1986..2136
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       1994
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200645200"
     variation       2061
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:35291896"
     variation       2102
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201195756"
     variation       2109
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113931583"
     variation       2111
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147864879"
     variation       2124
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367649651"
     exon            2137..2248
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       2137
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373637167"
     variation       2143
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200119939"
     variation       2157
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141451946"
     variation       2162
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150367272"
     variation       2165
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367618122"
     variation       2203
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138046370"
     variation       2220..2221
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:34022369"
     variation       2235
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372355893"
     variation       2238
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149093315"
     exon            2249..2337
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       2288
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202011004"
     variation       2329
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:143124134"
     variation       2335
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:202193926"
     exon            2338..2460
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       2440
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138624973"
     variation       2444..2445
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:34220354"
     variation       2457
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373465725"
     exon            2461..2586
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       2470
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376329180"
     variation       2472
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61917497"
     variation       2490
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:138941072"
     variation       2503
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146185523"
     variation       2522
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369668351"
     variation       2536
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:137864595"
     variation       2541
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373149305"
     exon            2587..2775
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       2659
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373264878"
     variation       2660
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201325210"
     variation       2691
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61730962"
     variation       2698
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:192927833"
     variation       2702
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:147160498"
     variation       2711
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150045915"
     exon            2776..2955
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       2805
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201810502"
     variation       2843
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368511222"
     variation       2857
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140823525"
     variation       2869
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200511262"
     variation       2909
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113985648"
     variation       2917
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144681794"
     variation       2918
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61757741"
     variation       2945
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201126471"
     exon            2956..3021
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       3020
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375535195"
     variation       3021
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369788968"
     exon            3022..5790
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /inference="alignment:Splign:1.39.8"
     variation       3025
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:142730346"
     variation       3054
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370440817"
     variation       3065
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371325602"
     variation       3082
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199801908"
     variation       3102
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:55923847"
     variation       3111
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374114077"
     variation       3124
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:367971027"
     variation       3155
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:371421286"
     variation       3175
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372609088"
     variation       3194
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:144504690"
     variation       3217
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3764010"
     variation       3231
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148395830"
     variation       3258
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183102078"
     variation       3411
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:7309005"
     variation       3520
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:56856599"
     variation       3584
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368935895"
     variation       3684
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142526071"
     variation       3685
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187768966"
     variation       3708
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:16932296"
     variation       3822
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:76599957"
     STS             3972..5627
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /standard_name="L18426"
                     /db_xref="UniSTS:34648"
     variation       4023
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11049095"
     variation       4029
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111818593"
     variation       4093
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:193300307"
     variation       4123
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:185140996"
     variation       4223..4224
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:200249833"
     variation       4233
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:78218603"
     variation       4240
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:190382759"
     variation       4265
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151006610"
     STS             4345..5385
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /standard_name="L18506"
                     /db_xref="UniSTS:54024"
     variation       4367
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:114845811"
     variation       4385
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:115719991"
     STS             4504..5385
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /standard_name="L18506"
                     /db_xref="UniSTS:54024"
     variation       4510
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139994391"
     variation       4513
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143369313"
     variation       4755
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:74074224"
     variation       4770
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146711132"
     variation       4787
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140345118"
     variation       4797
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368687919"
     variation       4834
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:74074225"
     variation       4837
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:192629982"
     variation       4862
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:150209760"
     variation       5066
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:184250045"
     variation       5067
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:188143172"
     variation       5084
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116652155"
     variation       5205
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:74462176"
     variation       5289
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:180903040"
     variation       5328
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373193073"
     variation       5345..5346
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:201424178"
     variation       5346..5348
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:57935514"
     variation       5347
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:74663411"
     variation       5361
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201472128"
     variation       5365
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145772097"
     variation       5379
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:148923051"
     variation       5381
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186290546"
     variation       5382
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190370936"
     variation       5413
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:12315453"
     variation       5457
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376952306"
     STS             5521..5623
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /standard_name="D11S3114"
                     /db_xref="UniSTS:152207"
     variation       5523
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:369436228"
     variation       5594
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143674494"
     variation       5598
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:182557126"
     variation       5626
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:186682610"
     variation       5634
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148164406"
     variation       5636
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144049521"
     variation       5637
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146907125"
     variation       5641
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369225674"
     polyA_signal    5765..5770
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
     polyA_site      5790
                     /gene="PPFIBP1"
                     /gene_synonym="hSGT2; hSgt2p; L2; SGT2"
ORIGIN      
gattcctgcagggagggaggagagaagggcggcagtgggagggggaggtacctggaactgggagtgatgtcagctcccagctcggtgcctgcccggattcctgacatggtgtagtgcaggcagggtggggaaaggacggggaaggactcgtgtgctgcgagctggcggccgggccggagtgctggggctttgaactccgagaggaggtggaccagaacttttggaactagtgccggcggctctccaccccccagtataaaagaacgtgtggatcactttgctgagtacatccaagatttgaagaactgaaataaatcagctttaaacctgctttttaaaaatacaaatggacacctaccagggaacggagatgtgtatcaagaaaggctggcacgtttagaaaatgataaagaatccctcgttcttcaggtaagtgtgttaacagaccaggtggaggctcagggagagaagattcgagatttggagttttgtcttgaagagcacagagagaagttgaatgccacagaagaaatgctgcagcaggagcttctaagtaggacatccttagaaactcagaagttggatctgatggctgaaatatctaacttgaagttgaaactgacagctgtagagaaggacagattggattatgaagataagttcagagacacagaggggctgattcaggagatcaatgatttgaggttaaaagttagtgaaatggacagtgagagacttcagtatgaaaaaaagcttaaatcaaccaaatctttaatggccaaactttctagcatgaaaatcaaggtgggtcagatgcagtatgaaaagcagcggatggaacaaaaatgggagtcactgaaggatgaactggcatctttaaaagaacaactagaagaaaaggaatctgaagtaaaaaggctacaagaaaaattggtttgcaagatgaaaggagaaggggttgaaattgttgatagagacatcgaagtacaaaaaatgaaaaaagctgtggagtccttgatggcagcaaatgaagaaaaggatcggaaaatagaagatcttcgacagtgcctgaacaggtacaagaaaatgcaagacacggtggtactggcccaaggcaaagatggagaatatgaagagctgctcaattccagttccatctcctctttgctggatgcacagggtttcagtgatctggagaaaagtccatcacccactccagtaatgggatctcccagttgtgacccatttaacacaagtgttcccgaagagttccatactaccatcttgcaagtttccatcccttcattattgccagcaactgtaagcatggaaacttctgaaaaatcaaagttgactcctaagccagagacttcatttgaagaaaatgatggaaacataatccttggtgccactgttgatacccaactgtgtgataaacttttaacttcaagtctgcagaagtccagcagcctgggcaatctgaagaaagagacatctgatggggaaaaggaaactattcagaagacttcagaggacagagctccggcagaaagcaggccatttgggacccttcctcccaggcccccagggcaggacacctccatggatgacaaccccttcggcactcgaaaagtcagatcttcctttggccggggcttttttaaaatcaaaagtaacaagagaacagcaagtgcaccaaacttagctgaaacagaaaaagagacagcagagcacctagatctggctggtgcttcttctcggccaaaagattcacagaggaacagtcccttccagataccgcctccatctccagattccaaaaagaaatccagaggtatcatgaaactctttggaaaacttaggagaagtcaatcaactacattcaacccagatgacatgtctgagcctgaattcaaaagaggagggacaagggcaaccgcggggccccgattaggttggtctcgagacttgggacagtctaacagtgacttggatatgccatttgccaagtggaccaaggagcaggtttgcaattggctgatggaacagggcttgggctcgtacctgaattctggcaagcactggattgcatctggccaaacgcttttgcaggcttctcaacaagatctagagaaggaacttggaatcaagcattcacttcatcgaaagaaactccagctagcactccaagccctgggatctgaagaagaaaccaatcatgggaagctggatttcaactgggtcactagatggttggatgacattggcctccctcaatataagacccagtttgatgaaggacgggttgatggtcgaatgctacattacatgactgttgatgacttactgtctctgaaggttgtaagtgtgctacaccatctcagtatcaaaagggccatccaggtcctgaggatcaataactttgaaccaaactgtctacggaggcggccatctgatgagaataccatcgccccatcagaagttcagaagtggactaaccatcgagtgatggagtggctgcgctccgtggacttggcagaatatgcgcccaatctcagaggcagtggtgtccatggtgggctcatggttctagagcctcgttttaacgtagaaacaatggctcagttattgaacatcccacccaataagactttgctgcgaagacatttggccactcatttcaaccttctgattggggctgaggcacagcaccagaagcgagatgccatggagctgccggattatgtacttctaacagctactgccaaagtgaagccaaagaaacttgcctttagcaattttgggaatttgagaaagaagaaacaggaagatggtgaagaatatgtttgtccaatggaattgggacaggcatcaggaagtgcatctaagaaaggatttaaacctggtttggatatgcgcctgtatgaggaagatgatttggaccggttagagcagatggaagattcagaagggacagtgagacagataggtgcattctctgaaggcatcaacaatctgacgcacatgttaaaagaagatgacatgtttaaagattttgctgcccgttcccccagtgccagcattacagatgaagactcaaacgtttgaccgtagcacctggatgaacattaggagtgcttagtcttttttctacttgcttttccaaacactcacagtatatacaacaggcagcggattgtctattgtttgttgttccaacttctgctgtcgagaagtttaaacagaaagcaggagtaatgtgccgattctgaagttgccacaaaaaataagacactggtgaatgagagtataattgtttttcttctatttaatgtaaaaatctgtgatatattatatttaaagtgttgcatttaagatgagtattttaccagagtgtttccattcatatccgcggtatggaggatttgaggaacagtaaccaggatgtgaatgattttgttacatcagtgttcactgtagccacctaagtaggacattatatgatttcagaatcaatatgtggaacttctttaagcattcagtgtgcccactaaatgccagccacacctccacttgcctcttattgtcttatttttatatatttttctaaatatatgtatatatacagtacatagaaaatagaacttttattttgtgacctaaggacgatggtgaaaagatcacgttttcaaaacaatctggtgatcagaatgttcatataccagctggtttctgaagaggtcagaatgatctttctccatactgacttttaacaatgttgatcattgaggctaaattaatatatatgaaatattcctttttgatgacaccacaaaattgttgaacagtttaagaatttcaaccttaatcttggatccctttacctcatatggaagaacttgagggacattagtatacttttttttaagatggagtcttgctctgtcacccaggttggagtgccatggcatgatcttggctcactgcaacctccacctcctgggtcaagccattctgcttcagccccaagtaggtgggactccaggcatgcaccaccatgcctggctaatttttgcatttttagtagagacagggtttcaccatattggccaggctgggactcgaactcctgaccttgtgatctgcccgcctcagcctcccaaagtactgggattataggcatgagccaccacgcccagcctgttatttttttattattattgtttttttttagtgacagagtctcattctgttgcccatgctggagtgcagtggcgtgatcatagctcactgcagccttgaattcctaggctccagtgatcctctcacctcagcttccctaatagctaggattacaggtgtgtggcctcccaccccaccccacccttcacacctggctgatttttcaaaaagtttttttgtagaaacagggtctcaccatgttgtccagcctggtctcaaactcctgtcctcaagtgatcctcccacctcagcctttcaaagtgctggaattacaggtgtgagccactctgcctggcctaccactaacttgaatacattcagaatcacctcctctccccaaaatttgtagaaatagtttttgaggaagccaaaagcaaagcagaaacctttacagtattgtttcttttctctttgttaactgtgtcattacagcaaaatactagcagtctgcctaaacatgttcattgtacatttctcaggctatcaatgaatggaggtttttaaaaagttgaatatttgtctgaacattttatttcaaagttcaaaaaaacagaggctgcaaaattcattttataatggctattttgtgacgataagatgtagttcatgtttttctgtagcactgggcccaaatattctttgtaaagaaaatcgctgcagcaaaaactgttactgtgtttattatatttgtagaagtattagaaaaatattctattttttattcagtgctgcgtaattacccatggtagccaaccctacaaaagacaggttttcacaaattgaggtggaggtgggcggttcagtatctgccactggacttgattataaactgtatttgaatatcagtggtattatcttttaagttgtcagcaagttaccaaggtattcattaaagaacttgtaatatcaaattactatttattcataacaattgatttgatgctaataataattttctttaaactctaccattcattatgtggtaactgtattgaacttactttatttggattttattttaatgtgactagatgtcaccacttcaaaaaatcaatttgttcttagaacctggttgaaaataccaggaaactgttacagacgccattttttttttttttgagacggagtcttgctctgttgcccaggctggagtgcagtggcacaatctcagctcactgcaagctccgcctcctgggttcacgccattctcccacctcagcttcccaagcagctgggactacaggtacctgccaccacgcctggctaattttgtttttgtatttttagtagagacggggtttcaccgtgttagccaggaaggtctcaatctcctgacctcgtgaatcgcccccctcggtctcccaaagtgctgggattacaggcgtgagccaccatgcccggcccaaatattttttattcaggatggtataacctaactgataataggtaataaggttaaatttttttatgacgtattttatttacaaatatcatacactgctggtgttaccatatgaaaggaaataaagtcaattgataattgcctcaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:8496 -> Biological process: GO:0007155 [cell adhesion] evidence: TAS
            GeneID:8496 -> Cellular component: GO:0005886 [plasma membrane] evidence: NAS

by @meso_cacase at DBCLS
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