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2024-04-19 21:01:09, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001197296            2656 bp    mRNA    linear   PRI 14-APR-2013
DEFINITION  Homo sapiens extracellular matrix protein 2, female organ and
            adipocyte specific (ECM2), transcript variant 3, mRNA.
ACCESSION   NM_001197296
VERSION     NM_001197296.1  GI:308818205
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2656)
  AUTHORS   Humphray,S.J., Oliver,K., Hunt,A.R., Plumb,R.W., Loveland,J.E.,
            Howe,K.L., Andrews,T.D., Searle,S., Hunt,S.E., Scott,C.E.,
            Jones,M.C., Ainscough,R., Almeida,J.P., Ambrose,K.D., Ashwell,R.I.,
            Babbage,A.K., Babbage,S., Bagguley,C.L., Bailey,J., Banerjee,R.,
            Barker,D.J., Barlow,K.F., Bates,K., Beasley,H., Beasley,O.,
            Bird,C.P., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.,
            Burrill,W., Burton,J., Carder,C., Carter,N.P., Chapman,J.C.,
            Chen,Y., Clarke,G., Clark,S.Y., Clee,C.M., Clegg,S., Collier,R.E.,
            Corby,N., Crosier,M., Cummings,A.T., Davies,J., Dhami,P., Dunn,M.,
            Dutta,I., Dyer,L.W., Earthrowl,M.E., Faulkner,L., Fleming,C.J.,
            Frankish,A., Frankland,J.A., French,L., Fricker,D.G., Garner,P.,
            Garnett,J., Ghori,J., Gilbert,J.G., Glison,C., Grafham,D.V.,
            Gribble,S., Griffiths,C., Griffiths-Jones,S., Grocock,R., Guy,J.,
            Hall,R.E., Hammond,S., Harley,J.L., Harrison,E.S., Hart,E.A.,
            Heath,P.D., Henderson,C.D., Hopkins,B.L., Howard,P.J., Howden,P.J.,
            Huckle,E., Johnson,C., Johnson,D., Joy,A.A., Kay,M., Keenan,S.,
            Kershaw,J.K., Kimberley,A.M., King,A., Knights,A., Laird,G.K.,
            Langford,C., Lawlor,S., Leongamornlert,D.A., Leversha,M., Lloyd,C.,
            Lloyd,D.M., Lovell,J., Martin,S., Mashreghi-Mohammadi,M.,
            Matthews,L., McLaren,S., McLay,K.E., McMurray,A., Milne,S.,
            Nickerson,T., Nisbett,J., Nordsiek,G., Pearce,A.V., Peck,A.I.,
            Porter,K.M., Pandian,R., Pelan,S., Phillimore,B., Povey,S.,
            Ramsey,Y., Rand,V., Scharfe,M., Sehra,H.K., Shownkeen,R.,
            Sims,S.K., Skuce,C.D., Smith,M., Steward,C.A., Swarbreck,D.,
            Sycamore,N., Tester,J., Thorpe,A., Tracey,A., Tromans,A.,
            Thomas,D.W., Wall,M., Wallis,J.M., West,A.P., Whitehead,S.L.,
            Willey,D.L., Williams,S.A., Wilming,L., Wray,P.W., Young,L.,
            Ashurst,J.L., Coulson,A., Blocker,H., Durbin,R., Sulston,J.E.,
            Hubbard,T., Jackson,M.J., Bentley,D.R., Beck,S., Rogers,J. and
            Dunham,I.
  TITLE     DNA sequence and analysis of human chromosome 9
  JOURNAL   Nature 429 (6990), 369-374 (2004)
   PUBMED   15164053
REFERENCE   2  (bases 1 to 2656)
  AUTHORS   Nishiu,J., Tanaka,T. and Nakamura,Y.
  TITLE     Identification of a novel gene (ECM2) encoding a putative
            extracellular matrix protein expressed predominantly in adipose and
            female-specific tissues and its chromosomal localization to 9q22.3
  JOURNAL   Genomics 52 (3), 378-381 (1998)
   PUBMED   9790758
REFERENCE   3  (bases 1 to 2656)
  AUTHORS   Oritani,K., Kanakura,Y., Aoyama,K., Yokota,T., Copeland,N.G.,
            Gilbert,D.J., Jenkins,N.A., Tomiyama,Y., Matsuzawa,Y. and
            Kincade,P.W.
  TITLE     Matrix glycoprotein SC1/ECM2 augments B lymphopoiesis
  JOURNAL   Blood 90 (9), 3404-3413 (1997)
   PUBMED   9345023
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DC300418.1, AB011792.1 and
            BX537976.1.
            
            Summary: ECM2 encodes extracellular matrix protein 2, so named
            because it shares extensive similarity with known extracelluar
            matrix proteins. Three transcript variants encoding different
            isoforms have been found for this gene. [provided by RefSeq, Oct
            2010].
            
            Transcript Variant: This variant (3) uses an alternate in-frame
            splice junction at the 5' end of an exon and differs in the 3' UTR
            and coding sequence compared to variant 1. The resulting isoform
            (3) lacks an internal segment and has a shorter and distinct
            C-terminus compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX537976.1 [ECO:0000332]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-122               DC300418.1         1-122
            123-354             AB011792.1         9-240
            355-2656            BX537976.1         318-2619
FEATURES             Location/Qualifiers
     source          1..2656
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q22.3"
     gene            1..2656
                     /gene="ECM2"
                     /note="extracellular matrix protein 2, female organ and
                     adipocyte specific"
                     /db_xref="GeneID:1842"
                     /db_xref="HGNC:3154"
                     /db_xref="MIM:603479"
     exon            1..160
                     /gene="ECM2"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    26..28
                     /gene="ECM2"
                     /note="upstream in-frame stop codon"
     exon            161..479
                     /gene="ECM2"
                     /inference="alignment:Splign:1.39.8"
     CDS             188..2119
                     /gene="ECM2"
                     /note="isoform 3 precursor is encoded by transcript
                     variant 3; matrix glycoprotein SC1/ECM2"
                     /codon_start=1
                     /product="extracellular matrix protein 2 isoform 3
                     precursor"
                     /protein_id="NP_001184225.1"
                     /db_xref="GI:308818206"
                     /db_xref="CCDS:CCDS56578.1"
                     /db_xref="GeneID:1842"
                     /db_xref="HGNC:3154"
                     /db_xref="MIM:603479"
                     /translation="
MKIAVLFCFFLLIIFQTDFGKNEEIPRKQRRKIYHRRLRKSSTSHKHRSNRQLGIQQTTVFTPVARLPIVNFDYSMEEKFESFSSFPGVESSYNVLPGKKGHCLVKGITMYNKAVWSPEPCTTCLCSDGRVLCDETMCHPQRCPQTVIPEGECCPVCSATEQREPTNLLHKQLPPPQVGMDRIVRKEALQSEEDEEVKEEDTEQKRETPESRNQGQLYSEGDSRGGDRKQRPGEERRLAHQQQRQGREEEEDEEEEGEEGEEDEEDEEDPVRGDMFRMPSRSPLPAPPRGTLRLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRCVSDAVLETVTNRSDVAFPLW
"
     sig_peptide     188..247
                     /gene="ECM2"
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
     mat_peptide     248..2116
                     /gene="ECM2"
                     /product="extracellular matrix protein 2 isoform 3"
     misc_feature    494..658
                     /gene="ECM2"
                     /note="von Willebrand factor type C domain; Region: VWC;
                     pfam00093"
                     /db_xref="CDD:109161"
     misc_feature    <1145..1549
                     /gene="ECM2"
                     /note="Leucine-rich repeats (LRRs), ribonuclease inhibitor
                     (RI)-like subfamily. LRRs are 20-29 residue sequence
                     motifs present in many proteins that participate in
                     protein-protein interactions and have different functions
                     and cellular locations. LRRs correspond...; Region:
                     LRR_RI; cl15309"
                     /db_xref="CDD:199167"
     misc_feature    1151..1336
                     /gene="ECM2"
                     /note="Leucine rich repeat; Region: LRR_8; pfam13855"
                     /db_xref="CDD:206026"
     misc_feature    order(1175..1177,1247..1249,1388..1390,1451..1453,
                     1457..1459,1529..1531)
                     /gene="ECM2"
                     /note="Substrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:29015"
     misc_feature    1367..1549
                     /gene="ECM2"
                     /note="Leucine rich repeat; Region: LRR_8; pfam13855"
                     /db_xref="CDD:206026"
     misc_feature    1577..1762
                     /gene="ECM2"
                     /note="Leucine rich repeat; Region: LRR_8; pfam13855"
                     /db_xref="CDD:206026"
     misc_feature    1595..>2077
                     /gene="ECM2"
                     /note="Leucine-rich repeats (LRRs), ribonuclease inhibitor
                     (RI)-like subfamily. LRRs are 20-29 residue sequence
                     motifs present in many proteins that participate in
                     protein-protein interactions and have different functions
                     and cellular locations. LRRs correspond...; Region:
                     LRR_RI; cl15309"
                     /db_xref="CDD:199167"
     misc_feature    1727..1900
                     /gene="ECM2"
                     /note="Leucine rich repeat; Region: LRR_8; pfam13855"
                     /db_xref="CDD:206026"
     misc_feature    1865..2050
                     /gene="ECM2"
                     /note="Leucine rich repeat; Region: LRR_8; pfam13855"
                     /db_xref="CDD:206026"
     variation       complement(245)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373531348"
     variation       complement(337)
                     /gene="ECM2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:199523075"
     variation       complement(354)
                     /gene="ECM2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:10120210"
     variation       complement(372)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:137948457"
     variation       complement(417)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200534289"
     variation       complement(426)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150291467"
     variation       complement(463)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:9299405"
     variation       complement(474)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201265258"
     exon            480..668
                     /gene="ECM2"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(513)
                     /gene="ECM2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:35496743"
     variation       complement(529)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143418555"
     variation       complement(537)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149220459"
     variation       complement(544)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34729575"
     variation       complement(622)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201771443"
     variation       complement(651)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147710026"
     variation       complement(652)
                     /gene="ECM2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:968040"
     variation       complement(660)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368912147"
     variation       complement(667)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139951554"
     exon            669..1175
                     /gene="ECM2"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(681)
                     /gene="ECM2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:149769253"
     variation       complement(688)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201071759"
     variation       complement(696)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139720616"
     variation       complement(726)
                     /gene="ECM2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200225062"
     variation       complement(731)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368116708"
     variation       complement(732)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34758505"
     variation       complement(746)
                     /gene="ECM2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:13293047"
     variation       complement(747)
                     /gene="ECM2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:200124000"
     variation       complement(750)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375328673"
     variation       complement(759)
                     /gene="ECM2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:13291847"
     variation       complement(760)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372289924"
     variation       complement(769)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368303849"
     variation       complement(785)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142198335"
     variation       complement(791)
                     /gene="ECM2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:13298061"
     variation       complement(792)
                     /gene="ECM2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:376085476"
     variation       complement(802)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:182133503"
     variation       complement(830)
                     /gene="ECM2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145991428"
     variation       complement(836)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367636482"
     variation       complement(852)
                     /gene="ECM2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:13297924"
     variation       complement(910)
                     /gene="ECM2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374472469"
     variation       complement(917)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142591312"
     variation       complement(935..936)
                     /gene="ECM2"
                     /replace=""
                     /replace="gtg"
                     /db_xref="dbSNP:200095306"
     variation       complement(941)
                     /gene="ECM2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:137929518"
     variation       complement(943)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34355623"
     variation       complement(953)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149244773"
     variation       complement(996)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369927306"
     variation       complement(1016)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138357265"
     variation       complement(1017)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372997619"
     variation       complement(1029)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143789386"
     variation       complement(1036)
                     /gene="ECM2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:41280067"
     variation       complement(1056)
                     /gene="ECM2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:142608064"
     variation       complement(1064)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138567683"
     variation       complement(1075)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148975367"
     variation       complement(1137)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201012391"
     variation       complement(1151)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147083553"
     variation       complement(1168)
                     /gene="ECM2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372699831"
     exon            1176..1291
                     /gene="ECM2"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1181)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141793116"
     variation       complement(1187)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142186054"
     variation       complement(1243)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:73651314"
     variation       complement(1246)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2296667"
     variation       complement(1272)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199972367"
     variation       complement(1278)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146339911"
     exon            1292..1427
                     /gene="ECM2"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1307)
                     /gene="ECM2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:139215803"
     variation       complement(1311)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41278707"
     variation       complement(1355)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370587410"
     variation       complement(1394)
                     /gene="ECM2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:142108843"
     variation       complement(1404)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376172195"
     variation       complement(1408)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146040741"
     variation       complement(1414)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113660659"
     variation       complement(1420)
                     /gene="ECM2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:144093801"
     exon            1428..1585
                     /gene="ECM2"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1462)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:35161698"
     variation       complement(1475)
                     /gene="ECM2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:373455336"
     variation       complement(1483)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369126996"
     variation       complement(1487)
                     /gene="ECM2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:199745267"
     variation       complement(1526)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150773107"
     variation       complement(1529)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376333101"
     variation       complement(1561)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141184307"
     variation       complement(1573)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148225586"
     variation       complement(1585)
                     /gene="ECM2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373635817"
     exon            1586..1725
                     /gene="ECM2"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1631)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369347015"
     variation       complement(1642)
                     /gene="ECM2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:143859115"
     variation       complement(1671)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372302066"
     exon            1726..2052
                     /gene="ECM2"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(1740)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376628552"
     variation       complement(1748..1749)
                     /gene="ECM2"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:34868349"
     variation       complement(1774)
                     /gene="ECM2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:199713916"
     variation       complement(1816)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143452414"
     variation       complement(1829)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199600306"
     variation       complement(1834)
                     /gene="ECM2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:373764507"
     variation       complement(1845)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34518968"
     variation       complement(1882)
                     /gene="ECM2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:147126273"
     variation       complement(1906)
                     /gene="ECM2"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:141859598"
     variation       complement(1932)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201745324"
     variation       complement(1948)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186648835"
     variation       complement(1972)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138868045"
     variation       complement(1991)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150249574"
     variation       complement(2003)
                     /gene="ECM2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:140976209"
     variation       complement(2050)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370627896"
     variation       complement(2051)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:151070730"
     variation       complement(2052)
                     /gene="ECM2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200394678"
     exon            2053..2655
                     /gene="ECM2"
                     /inference="alignment:Splign:1.39.8"
     variation       complement(2086)
                     /gene="ECM2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375600278"
     variation       complement(2196)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145750718"
     variation       complement(2197)
                     /gene="ECM2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:374607616"
     variation       complement(2295)
                     /gene="ECM2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:183266211"
     variation       complement(2310)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:7869742"
     variation       complement(2593)
                     /gene="ECM2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:111626878"
     variation       complement(2624)
                     /gene="ECM2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:115693996"
ORIGIN      
gggaggcagttattttagattttactaagaagttcagcaaatacttttcaacattcccttctgtcctttctttgtttttaaagaaagctctgattttgtttcattttcagctggagacttaaatgacaccaagcaaagcctacttagtttagatctccagaaattggctggtggaaaaaaatcaaacatgaagattgcagttttgttttgtttttttctgcttatcatttttcaaactgactttggaaaaaatgaagaaattcctaggaagcaaaggaggaagatctaccacagaaggttgaggaaaagttcaacctcacacaagcacagatcaaacagacagcttggaattcagcaaacaacagtttttacaccagtagcaagacttcctattgttaactttgattatagcatggaggaaaagtttgaatccttttcaagttttcctggagtagaatcaagttataatgtgttaccaggaaagaagggacactgtttggtaaagggcataaccatgtacaacaaagctgtgtggtcgcctgagccctgcactacctgcctctgctcagatggaagagttctttgtgatgaaaccatgtgccatccccagaggtgcccccaaacagttatacctgaaggggaatgctgcccggtctgctccgctactgaacaaagagaacctaccaatttacttcataagcaactgccacctcctcaggtgggaatggaccgaatagtaagaaaagaagcacttcaatctgaggaggatgaagaagtgaaagaagaagatacagagcaaaagagagagacccctgaatctagaaatcaggggcaactttacagtgagggggacagcagaggaggagacagaaagcagaggcctggagaggagaggaggctggcacaccagcaacaacgccaaggaagggaggaggaggaggatgaggaggaggagggtgaggagggtgaggaggatgaggaggacgaggaggacccggtaagaggagatatgttccgaatgccctctcgatccccgcttcctgctcctcccagaggcacactgcgcctgccaagcgggtgctctctgtcctacaggaccatcagctgcatcaacgccatgcttacccagataccaccgctgacagcaccacagataacaagtctggagctcactggcaattccatcgcctccatcccagatgaagcatttaatggattaccaaatttggaaaggcttgatctgagtaaaaataatatcacttcttcaggcataggtccaaaagcattcaagcttctgaagaagttaatgcgtttgaatatggatggaaataatttgatacagattccttcacaattgccatctacattagaagaacttaaagtcaatgagaacaatcttcaggctatcgatgaagaaagtttatcagacttaaatcagttggtcaccttagaattggaaggaaacaatctcagtgaagccaatgtcaatcctttagctttcaaacctttgaagagcctagcctacttgcgtctgggaaaaaataaatttagaattataccgcagggtcttcctggttctattgaggaattatacctagaaaataaccaaattgaagaaataactgaaatttgtttcaatcataccagaaagatcaatgtcattgtactacgttataacaaaattgaagaaaataggattgctcctttagcctggataaatcaagaaaatctagaatccattgatctctcctacaacaagctctatcacgtcccgtcctatctacccaagtccttgctgcacctagtactccttgggaaccagattgaacggatccctggctatgtgtttggccacatggaaccaggcctggaatacttgtacctgtcatttaacaaacttgctgatgatggcatggaccgtgtctccttctatggggcatatcattctctgagagaattatttctggatcacaatgacttaaaatctataccacctgggatacaagaaatgaaagcactacattttctgaggctgaacaacaacaagatacgctgtgtttcagatgctgttctagagacagtgacaaacagatcagatgtggcctttcctctctggtagaggcaataagcaggaaatcaaacagacaagtaagcaggcaagtgctgtgcagtcagaaaaatgggtgacaatgcgacgagcacactggggcctgagggccgccaggagactacggccaccctcaacggcctggattaacagcagatccagaccggtgcctgtggagcagacgcactgtgggcttgctgtgtatgtcgcttctcaactctgctctggctgcagaatcccaagaaaaaaatgaaaatcagaatgactgattgaagcttttttcttaagtggaagttgtacttatttctactgattttataatttttaaaatatggctagcatggaacttgttcagccctgaaatttcatgatgttctagatgggaagttttaattccataaaaaagtgataaatgtccttatagcaaacactcttcacaatataatgtactaaaaaacagatgttctgtttggcttcaaaaattacactataattactaacacacatatacactaaagaagtcctggtctagccatgatctaaaaataa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:1842 -> Molecular function: GO:0005178 [integrin binding] evidence: TAS
            GeneID:1842 -> Molecular function: GO:0008201 [heparin binding] evidence: IEA
            GeneID:1842 -> Molecular function: GO:0070052 [collagen V binding] evidence: IEA
            GeneID:1842 -> Biological process: GO:0007160 [cell-matrix adhesion] evidence: TAS
            GeneID:1842 -> Biological process: GO:0010811 [positive regulation of cell-substrate adhesion] evidence: IEA
            GeneID:1842 -> Biological process: GO:0030198 [extracellular matrix organization] evidence: IEA
            GeneID:1842 -> Cellular component: GO:0005578 [proteinaceous extracellular matrix] evidence: TAS
            GeneID:1842 -> Cellular component: GO:0005614 [interstitial matrix] evidence: IEA

by @meso_cacase at DBCLS
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