2024-04-19 23:37:12, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001193426 2608 bp mRNA linear PRI 17-APR-2013 DEFINITION Homo sapiens suppressor of variegation 3-9 homolog 2 (Drosophila) (SUV39H2), transcript variant 4, mRNA. ACCESSION NM_001193426 VERSION NM_001193426.1 GI:301171604 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 2608) AUTHORS Syreeni,A., El-Osta,A., Forsblom,C., Sandholm,N., Parkkonen,M., Tarnow,L., Parving,H.H., McKnight,A.J., Maxwell,A.P., Cooper,M.E. and Groop,P.H. CONSRTM FinnDiane Study Group TITLE Genetic examination of SETD7 and SUV39H1/H2 methyltransferases and the risk of diabetes complications in patients with type 1 diabetes JOURNAL Diabetes 60 (11), 3073-3080 (2011) PUBMED 21896933 REMARK GeneRIF: genetic association studies in a Finnish population with type I diabetes: The minor T allele of exonic SNP rs17353856 in SUV39H2 is associated with diabetic retinopathy (in a larger meta-analysis); thus an genetic variation may be protective. REFERENCE 2 (bases 1 to 2608) AUTHORS Benlhabib,H. and Mendelson,C.R. TITLE Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia JOURNAL Mol. Cell. Biol. 31 (10), 1949-1958 (2011) PUBMED 21402781 REMARK GeneRIF: findings suggest that Suv39H1 and Suv39H2 are key hypoxia-induced methyltransferases; their decline in fetal lung during late gestation is critical for epigenetic changes resulting in the developmental induction of SP-A REFERENCE 3 (bases 1 to 2608) AUTHORS Sun,X.J., Xu,P.F., Zhou,T., Hu,M., Fu,C.T., Zhang,Y., Jin,Y., Chen,Y., Chen,S.J., Huang,Q.H., Liu,T.X. and Chen,Z. TITLE Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes JOURNAL PLoS ONE 3 (1), E1499 (2008) PUBMED 18231586 REMARK GeneRIF: The SUV39H2 gene is found in tetrapods (e.g., human, mouse and frog) but not in zebrafish, suggesting that this gene is generated by a tetrapod lineage-specific gene duplication event. Publication Status: Online-Only REFERENCE 4 (bases 1 to 2608) AUTHORS Wu,C., Ma,M.H., Brown,K.R., Geisler,M., Li,L., Tzeng,E., Jia,C.Y., Jurisica,I. and Li,S.S. TITLE Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening JOURNAL Proteomics 7 (11), 1775-1785 (2007) PUBMED 17474147 REFERENCE 5 (bases 1 to 2608) AUTHORS Yoon,K.A., Hwangbo,B., Kim,I.J., Park,S., Kim,H.S., Kee,H.J., Lee,J.E., Jang,Y.K., Park,J.G. and Lee,J.S. TITLE Novel polymorphisms in the SUV39H2 histone methyltransferase and the risk of lung cancer JOURNAL Carcinogenesis 27 (11), 2217-2222 (2006) PUBMED 16774942 REMARK GeneRIF: a novel SUV39H2 polymorphism may have a role in lung cancer susceptibility for smokers GeneRIF: Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) REFERENCE 6 (bases 1 to 2608) AUTHORS Frontelo,P., Leader,J.E., Yoo,N., Potocki,A.C., Crawford,M., Kulik,M. and Lechleider,R.J. TITLE Suv39h histone methyltransferases interact with Smads and cooperate in BMP-induced repression JOURNAL Oncogene 23 (30), 5242-5251 (2004) PUBMED 15107829 REFERENCE 7 (bases 1 to 2608) AUTHORS Deloukas,P., Earthrowl,M.E., Grafham,D.V., Rubenfield,M., French,L., Steward,C.A., Sims,S.K., Jones,M.C., Searle,S., Scott,C., Howe,K., Hunt,S.E., Andrews,T.D., Gilbert,J.G., Swarbreck,D., Ashurst,J.L., Taylor,A., Battles,J., Bird,C.P., Ainscough,R., Almeida,J.P., Ashwell,R.I., Ambrose,K.D., Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Bates,K., Beasley,H., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Cahill,P., Camire,D., Carter,N.P., Chapman,J.C., Clark,S.Y., Clarke,G., Clee,C.M., Clegg,S., Corby,N., Coulson,A., Dhami,P., Dutta,I., Dunn,M., Faulkner,L., Frankish,A., Frankland,J.A., Garner,P., Garnett,J., Gribble,S., Griffiths,C., Grocock,R., Gustafson,E., Hammond,S., Harley,J.L., Hart,E., Heath,P.D., Ho,T.P., Hopkins,B., Horne,J., Howden,P.J., Huckle,E., Hynds,C., Johnson,C., Johnson,D., Kana,A., Kay,M., Kimberley,A.M., Kershaw,J.K., Kokkinaki,M., Laird,G.K., Lawlor,S., Lee,H.M., Leongamornlert,D.A., Laird,G., Lloyd,C., Lloyd,D.M., Loveland,J., Lovell,J., McLaren,S., McLay,K.E., McMurray,A., Mashreghi-Mohammadi,M., Matthews,L., Milne,S., Nickerson,T., Nguyen,M., Overton-Larty,E., Palmer,S.A., Pearce,A.V., Peck,A.I., Pelan,S., Phillimore,B., Porter,K., Rice,C.M., Rogosin,A., Ross,M.T., Sarafidou,T., Sehra,H.K., Shownkeen,R., Skuce,C.D., Smith,M., Standring,L., Sycamore,N., Tester,J., Thorpe,A., Torcasso,W., Tracey,A., Tromans,A., Tsolas,J., Wall,M., Walsh,J., Wang,H., Weinstock,K., West,A.P., Willey,D.L., Whitehead,S.L., Wilming,L., Wray,P.W., Young,L., Chen,Y., Lovering,R.C., Moschonas,N.K., Siebert,R., Fechtel,K., Bentley,D., Durbin,R., Hubbard,T., Doucette-Stamm,L., Beck,S., Smith,D.R. and Rogers,J. TITLE The DNA sequence and comparative analysis of human chromosome 10 JOURNAL Nature 429 (6990), 375-381 (2004) PUBMED 15164054 REFERENCE 8 (bases 1 to 2608) AUTHORS Ait-Si-Ali,S., Guasconi,V., Fritsch,L., Yahi,H., Sekhri,R., Naguibneva,I., Robin,P., Cabon,F., Polesskaya,A. and Harel-Bellan,A. TITLE A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells JOURNAL EMBO J. 23 (3), 605-615 (2004) PUBMED 14765126 REFERENCE 9 (bases 1 to 2608) AUTHORS O'Carroll,D., Scherthan,H., Peters,A.H., Opravil,S., Haynes,A.R., Laible,G., Rea,S., Schmid,M., Lebersorger,A., Jerratsch,M., Sattler,L., Mattei,M.G., Denny,P., Brown,S.D., Schweizer,D. and Jenuwein,T. TITLE Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression JOURNAL Mol. Cell. Biol. 20 (24), 9423-9433 (2000) PUBMED 11094092 REFERENCE 10 (bases 1 to 2608) AUTHORS Rea,S., Eisenhaber,F., O'Carroll,D., Strahl,B.D., Sun,Z.W., Schmid,M., Opravil,S., Mechtler,K., Ponting,C.P., Allis,C.D. and Jenuwein,T. TITLE Regulation of chromatin structure by site-specific histone H3 methyltransferases JOURNAL Nature 406 (6796), 593-599 (2000) PUBMED 10949293 COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB040298.1, BC029360.1 and BC007754.2. Transcript Variant: This variant (4) uses an alternate donor splice site at an internal coding exon compared to variant 1, maintaining the reading frame, and resulting in a shorter isoform (3) missing an internal protein segment compared compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC029360.1, BG501493.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025084, ERS025085 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-80 DB040298.1 1-80 81-1366 BC029360.1 1-1286 1367-2608 BC007754.2 1852-3093 FEATURES Location/Qualifiers source 1..2608 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="10" /map="10p13" gene 1..2608 /gene="SUV39H2" /gene_synonym="KMT1B" /note="suppressor of variegation 3-9 homolog 2 (Drosophila)" /db_xref="GeneID:79723" /db_xref="HGNC:17287" /db_xref="MIM:606503" exon 1..137 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" misc_feature 92..94 /gene="SUV39H2" /gene_synonym="KMT1B" /note="upstream in-frame stop codon" variation 102 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:375333545" CDS 107..799 /gene="SUV39H2" /gene_synonym="KMT1B" /EC_number="2.1.1.43" /note="isoform 3 is encoded by transcript variant 4; histone-lysine N-methyltransferase SUV39H2; H3-K9-HMTase 2; su(var)3-9 homolog 2; lysine N-methyltransferase 1B; histone H3-K9 methyltransferase 2" /codon_start=1 /product="histone-lysine N-methyltransferase SUV39H2 isoform 3" /protein_id="NP_001180355.1" /db_xref="GI:301171605" /db_xref="CCDS:CCDS53493.1" /db_xref="GeneID:79723" /db_xref="HGNC:17287" /db_xref="MIM:606503" /translation="
MAAVGAEARGAWCVPCLVSLDTLQELCRKEKLTCKSIGITKRNLNNYEVEYLCDYKVVKDMEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN
" misc_feature 245..385 /gene="SUV39H2" /gene_synonym="KMT1B" /note="Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; Region: CHROMO; cd00024" /db_xref="CDD:28908" misc_feature order(245..247,302..304,308..310,317..319,329..331, 341..343,353..358) /gene="SUV39H2" /gene_synonym="KMT1B" /note="histone binding site; other site" /db_xref="CDD:28908" misc_feature <404..685 /gene="SUV39H2" /gene_synonym="KMT1B" /note="SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; Region: SET; smart00317" /db_xref="CDD:197649" exon 138..283 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" variation 214 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:369200305" variation 225 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:373386573" exon 284..415 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" variation 373 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:148153307" variation 394 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:376764262" variation 396 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:140852434" exon 416..562 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" variation 475 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:190174096" variation 487 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:183140822" variation 488 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:148667087" variation 532 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:17353856" variation 538 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:369186882" variation 553 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:147278353" exon 563..692 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" variation 607 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:61730323" variation 632 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:369793867" exon 693..2602 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" variation 768 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:199727444" variation 778 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:144605484" variation 794 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:201395473" variation 818 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:375126181" variation 854 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:368830300" variation 890 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:113301024" variation 911 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:373511332" variation 926 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:11547181" variation 947 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:373567048" variation 958 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:180989547" variation 962 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="" /replace="g" /db_xref="dbSNP:375028927" STS 1081..1202 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="RH48597" /db_xref="UniSTS:71892" variation 1139 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:116910335" variation 1152 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:75420442" polyA_signal 1314..1319 /gene="SUV39H2" /gene_synonym="KMT1B" variation 1333..1335 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="" /replace="aat" /db_xref="dbSNP:367684066" polyA_site 1334 /gene="SUV39H2" /gene_synonym="KMT1B" polyA_site 1350 /gene="SUV39H2" /gene_synonym="KMT1B" polyA_signal 1359..1364 /gene="SUV39H2" /gene_synonym="KMT1B" variation 1371..1374 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="" /replace="aatt" /db_xref="dbSNP:371874353" polyA_site 1376 /gene="SUV39H2" /gene_synonym="KMT1B" polyA_site 1387 /gene="SUV39H2" /gene_synonym="KMT1B" variation 1484 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:142967205" variation 1541 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:185218421" variation 1603 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:41284455" variation 1694 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:11594111" variation 1765 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:190438184" variation 1881 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:181251834" variation 2019 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:61843036" variation 2156 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:75516757" variation 2178 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:376829730" variation 2236 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:150828159" variation 2361 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:139176971" variation 2425 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:11259385" STS 2464..2546 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="L18426" /db_xref="UniSTS:34648" STS 2465..2544 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="D5S1597E" /db_xref="UniSTS:151019" STS 2466..2568 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="D11S2921" /db_xref="UniSTS:152074" STS 2468..2537 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="D1S1423" /db_xref="UniSTS:149619" variation 2505 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:186353154" variation 2523 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:191603474" variation 2524 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:371491790" variation 2543 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:183557434" variation 2591 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="t" /db_xref="dbSNP:79193913" ORIGIN
aacaagccccggcccccaagtcccgcgcgggccggccaggggcggggcgtcgggccagctgagctatcccgtcagaccgcgccagtttgaatgaaagctctacaagatggcggcggtcggggccgaggcgcgaggagcttggtgtgtgccttgcctagtttcacttgatactcttcaggaattatgtagaaaagaaaagctcacatgtaaatcgattggaatcaccaaaaggaatctaaacaattatgaggtggaatacttgtgtgactacaaggtagtaaaggatatggaatattatcttgtaaaatggaaaggatggccagattctacaaatacttgggaacctttgcaaaatctgaagtgcccgttactgcttcagcaattctctaatgacaagcataattatttatctcaggtaatcacaagtgaagaagctgaaagacgaggacagttctatgacaacaagggaatcacgtatctctttgatctggactatgagtctgatgaattcacagtggatgcggctcgatacggcaatgtgtctcattttgtgaatcacagctgtgacccaaatcttcaggtgttcaatgttttcattgataacctcgatactcgtcttccccgaatagcattgttttccacaagaaccataaatgctggagaagagctgacttttgattatcaaatgaaaggttctggagatatatcttcagattctattgaccacagcccagccaaaaagagggtcagaacagtatgtaaatgtggagctgtgacttgcagaggttacctcaactgaactttttcaggaaatagagctgatgattataatatttttttcctaatgttaacatttttaaaaatacatatttgggactcttattatcaaggttctacctatgttaatttacaattcatgtttcaagacatttgccaaatgtattaccgatgcctctgaaaagggggtcactgggtctcatagactgatatgaagtcgacatatttatagtgcttagagaccaaactaatggaaggcagactatttacagcttagtatatgtgtacttaagtctatgtgaacagagaaatgcctcccgtagtgtttgaaagcgttaagctgataatgtaattaacaactgctgagagatcaaagattcaacttgccatacacctcaaattcggagaaacagttaatttgggcaaatctacagttctgtttttgctactctattgtcattcctgtttaatactcactgtacttgtatttgagacaaataggtgatactgaattttatactgttttctacttttccattaaaacattggcacctcaatgataaagaaatttaaggtataaaattaaatgtaaaaattaatttcagcttcatttcgtatttcgaagcaatctagactgttgtgatgagtgtatgtctgaacctgtaattcttaaaagacttcttaatcttctagaagaaaaatctccgaagagctctctctagaagtccaaaatggctagccattatgcttctttgaaaggacatgataatgggaccaggatggttttttggagtaccaagcaaggggaatggagcactttaagggcgcctgttagtaacatgaattggaaatctgtgtcgagtacctctgatctaaacggtaaaacaagctgcctggagagcagctgtacctaacaatactgtaatgtacattaacattacagcctctcaatttcaggcaggtgtaacagttcctttccaccagatttaatatttttatacttcctgcaggttcttcttaaaaagtaatctatatttttgaactgatacttgttttatacataaattttttttagatgtgataaagctaaacttggccaaagtgtgtgcctgaattattagacctttttattagtcaacctacgaagactaaaatagaatatattagttttcaagggagtgggaggcttccaacatagtattgaatctcaggaaaaactattctttcatgtctgattctgagatttctaattgtgttgtgaaaatgataaatgcagcaaatctagctttcagtattcctaatttttacctaagctcattgctccaggctttgattacctaaaataagcttggataaaattgaaccaacttcaagaatgcagcacttcttaatctttagctctttcttgggagaagctagactttattcattatattgctatgacaacttcactctttcataatatataggataaattgtttacatgattggaccctcagattctgttaaccaaaattgcagaatggggggccaggcctgtgtggtggctcacacctgtgatcccagcactttgggaggctgaggtaggaggatcacgtgaggtcgggagttcaagaccagcctggccatcatggtgaaaccctgtctctactgaaaatacaaaaattagccgggcgtggtggcacacgcctgtagtcccagctactcaggaggctgaggcaggagaatcacttgaattcaggaggcggaggttgcagtgagccaagatcataccactgcactgcagcctgagtgacacagtaagactgtctccaaaaaaaaaaaaaaaaaa
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ANNOTATIONS from NCBI Entrez Gene (20130726): GeneID:79723 -> Molecular function: GO:0003682 [chromatin binding] evidence: IEA GeneID:79723 -> Molecular function: GO:0005515 [protein binding] evidence: IPI GeneID:79723 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA GeneID:79723 -> Molecular function: GO:0046974 [histone methyltransferase activity (H3-K9 specific)] evidence: IDA GeneID:79723 -> Biological process: GO:0006333 [chromatin assembly or disassembly] evidence: IMP GeneID:79723 -> Biological process: GO:0006338 [chromatin remodeling] evidence: IDA GeneID:79723 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA GeneID:79723 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IEA GeneID:79723 -> Biological process: GO:0007140 [male meiosis] evidence: IEA GeneID:79723 -> Biological process: GO:0030154 [cell differentiation] evidence: IEA GeneID:79723 -> Cellular component: GO:0000775 [chromosome, centromeric region] evidence: IEA GeneID:79723 -> Cellular component: GO:0000785 [chromatin] evidence: IDA GeneID:79723 -> Cellular component: GO:0005720 [nuclear heterochromatin] evidence: IEA ANNOTATIONS from NCBI Entrez Gene (20130726): NP_001180355 -> EC 2.1.1.43
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