2024-04-26 04:03:39, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001193425 3106 bp mRNA linear PRI 18-APR-2013 DEFINITION Homo sapiens suppressor of variegation 3-9 homolog 2 (Drosophila) (SUV39H2), transcript variant 2, mRNA. ACCESSION NM_001193425 VERSION NM_001193425.1 GI:301171596 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 3106) AUTHORS Syreeni,A., El-Osta,A., Forsblom,C., Sandholm,N., Parkkonen,M., Tarnow,L., Parving,H.H., McKnight,A.J., Maxwell,A.P., Cooper,M.E. and Groop,P.H. CONSRTM FinnDiane Study Group TITLE Genetic examination of SETD7 and SUV39H1/H2 methyltransferases and the risk of diabetes complications in patients with type 1 diabetes JOURNAL Diabetes 60 (11), 3073-3080 (2011) PUBMED 21896933 REMARK GeneRIF: genetic association studies in a Finnish population with type I diabetes: The minor T allele of exonic SNP rs17353856 in SUV39H2 is associated with diabetic retinopathy (in a larger meta-analysis); thus an genetic variation may be protective. REFERENCE 2 (bases 1 to 3106) AUTHORS Benlhabib,H. and Mendelson,C.R. TITLE Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia JOURNAL Mol. Cell. Biol. 31 (10), 1949-1958 (2011) PUBMED 21402781 REMARK GeneRIF: findings suggest that Suv39H1 and Suv39H2 are key hypoxia-induced methyltransferases; their decline in fetal lung during late gestation is critical for epigenetic changes resulting in the developmental induction of SP-A REFERENCE 3 (bases 1 to 3106) AUTHORS Sun,X.J., Xu,P.F., Zhou,T., Hu,M., Fu,C.T., Zhang,Y., Jin,Y., Chen,Y., Chen,S.J., Huang,Q.H., Liu,T.X. and Chen,Z. TITLE Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes JOURNAL PLoS ONE 3 (1), E1499 (2008) PUBMED 18231586 REMARK GeneRIF: The SUV39H2 gene is found in tetrapods (e.g., human, mouse and frog) but not in zebrafish, suggesting that this gene is generated by a tetrapod lineage-specific gene duplication event. Publication Status: Online-Only REFERENCE 4 (bases 1 to 3106) AUTHORS Wu,C., Ma,M.H., Brown,K.R., Geisler,M., Li,L., Tzeng,E., Jia,C.Y., Jurisica,I. and Li,S.S. TITLE Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening JOURNAL Proteomics 7 (11), 1775-1785 (2007) PUBMED 17474147 REFERENCE 5 (bases 1 to 3106) AUTHORS Yoon,K.A., Hwangbo,B., Kim,I.J., Park,S., Kim,H.S., Kee,H.J., Lee,J.E., Jang,Y.K., Park,J.G. and Lee,J.S. TITLE Novel polymorphisms in the SUV39H2 histone methyltransferase and the risk of lung cancer JOURNAL Carcinogenesis 27 (11), 2217-2222 (2006) PUBMED 16774942 REMARK GeneRIF: a novel SUV39H2 polymorphism may have a role in lung cancer susceptibility for smokers GeneRIF: Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) REFERENCE 6 (bases 1 to 3106) AUTHORS Frontelo,P., Leader,J.E., Yoo,N., Potocki,A.C., Crawford,M., Kulik,M. and Lechleider,R.J. TITLE Suv39h histone methyltransferases interact with Smads and cooperate in BMP-induced repression JOURNAL Oncogene 23 (30), 5242-5251 (2004) PUBMED 15107829 REFERENCE 7 (bases 1 to 3106) AUTHORS Deloukas,P., Earthrowl,M.E., Grafham,D.V., Rubenfield,M., French,L., Steward,C.A., Sims,S.K., Jones,M.C., Searle,S., Scott,C., Howe,K., Hunt,S.E., Andrews,T.D., Gilbert,J.G., Swarbreck,D., Ashurst,J.L., Taylor,A., Battles,J., Bird,C.P., Ainscough,R., Almeida,J.P., Ashwell,R.I., Ambrose,K.D., Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Bates,K., Beasley,H., Bray-Allen,S., Brown,A.J., Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Cahill,P., Camire,D., Carter,N.P., Chapman,J.C., Clark,S.Y., Clarke,G., Clee,C.M., Clegg,S., Corby,N., Coulson,A., Dhami,P., Dutta,I., Dunn,M., Faulkner,L., Frankish,A., Frankland,J.A., Garner,P., Garnett,J., Gribble,S., Griffiths,C., Grocock,R., Gustafson,E., Hammond,S., Harley,J.L., Hart,E., Heath,P.D., Ho,T.P., Hopkins,B., Horne,J., Howden,P.J., Huckle,E., Hynds,C., Johnson,C., Johnson,D., Kana,A., Kay,M., Kimberley,A.M., Kershaw,J.K., Kokkinaki,M., Laird,G.K., Lawlor,S., Lee,H.M., Leongamornlert,D.A., Laird,G., Lloyd,C., Lloyd,D.M., Loveland,J., Lovell,J., McLaren,S., McLay,K.E., McMurray,A., Mashreghi-Mohammadi,M., Matthews,L., Milne,S., Nickerson,T., Nguyen,M., Overton-Larty,E., Palmer,S.A., Pearce,A.V., Peck,A.I., Pelan,S., Phillimore,B., Porter,K., Rice,C.M., Rogosin,A., Ross,M.T., Sarafidou,T., Sehra,H.K., Shownkeen,R., Skuce,C.D., Smith,M., Standring,L., Sycamore,N., Tester,J., Thorpe,A., Torcasso,W., Tracey,A., Tromans,A., Tsolas,J., Wall,M., Walsh,J., Wang,H., Weinstock,K., West,A.P., Willey,D.L., Whitehead,S.L., Wilming,L., Wray,P.W., Young,L., Chen,Y., Lovering,R.C., Moschonas,N.K., Siebert,R., Fechtel,K., Bentley,D., Durbin,R., Hubbard,T., Doucette-Stamm,L., Beck,S., Smith,D.R. and Rogers,J. TITLE The DNA sequence and comparative analysis of human chromosome 10 JOURNAL Nature 429 (6990), 375-381 (2004) PUBMED 15164054 REFERENCE 8 (bases 1 to 3106) AUTHORS Ait-Si-Ali,S., Guasconi,V., Fritsch,L., Yahi,H., Sekhri,R., Naguibneva,I., Robin,P., Cabon,F., Polesskaya,A. and Harel-Bellan,A. TITLE A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells JOURNAL EMBO J. 23 (3), 605-615 (2004) PUBMED 14765126 REFERENCE 9 (bases 1 to 3106) AUTHORS O'Carroll,D., Scherthan,H., Peters,A.H., Opravil,S., Haynes,A.R., Laible,G., Rea,S., Schmid,M., Lebersorger,A., Jerratsch,M., Sattler,L., Mattei,M.G., Denny,P., Brown,S.D., Schweizer,D. and Jenuwein,T. TITLE Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression JOURNAL Mol. Cell. Biol. 20 (24), 9423-9433 (2000) PUBMED 11094092 REFERENCE 10 (bases 1 to 3106) AUTHORS Rea,S., Eisenhaber,F., O'Carroll,D., Strahl,B.D., Sun,Z.W., Schmid,M., Opravil,S., Mechtler,K., Ponting,C.P., Allis,C.D. and Jenuwein,T. TITLE Regulation of chromatin structure by site-specific histone H3 methyltransferases JOURNAL Nature 406 (6796), 593-599 (2000) PUBMED 10949293 COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU928392.1, AC069544.9, AL360083.27 and BC007754.2. Transcript Variant: This variant (2) contains an alternate 5' terminal exon compared to variant 1. This results in translation initiation from an in-frame, downstream AUG, and a shorter isoform (2) compared to isoform 1. Variants 2 and 3 encode the same isoform. ##Evidence-Data-START## CDS exon combination :: BC007754.2, AK027067.1 [ECO:0000331] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-373 BU928392.1 22-394 374-913 AC069544.9 210216-210755 914-1060 AC069544.9 212777-212923 1061-1190 AC069544.9 214371-214500 1191-1862 AL360083.27 2778-3449 1863-3106 BC007754.2 1850-3093 FEATURES Location/Qualifiers source 1..3106 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="10" /map="10p13" gene 1..3106 /gene="SUV39H2" /gene_synonym="KMT1B" /note="suppressor of variegation 3-9 homolog 2 (Drosophila)" /db_xref="GeneID:79723" /db_xref="HGNC:17287" /db_xref="MIM:606503" exon 1..95 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" variation 19 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:375333545" misc_feature 56..58 /gene="SUV39H2" /gene_synonym="KMT1B" /note="upstream in-frame stop codon" variation 65 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:374848659" variation 75 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:192886481" variation 79 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:184647815" exon 96..241 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" variation 172 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:369200305" variation 183 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:373386573" exon 242..913 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" CDS 245..1297 /gene="SUV39H2" /gene_synonym="KMT1B" /EC_number="2.1.1.43" /note="isoform 2 is encoded by transcript variant 2; histone-lysine N-methyltransferase SUV39H2; H3-K9-HMTase 2; su(var)3-9 homolog 2; lysine N-methyltransferase 1B; histone H3-K9 methyltransferase 2" /codon_start=1 /product="histone-lysine N-methyltransferase SUV39H2 isoform 2" /protein_id="NP_001180354.1" /db_xref="GI:301171597" /db_xref="CCDS:CCDS7104.1" /db_xref="GeneID:79723" /db_xref="HGNC:17287" /db_xref="MIM:606503" /translation="
MEYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVKKGKAITPKDNNKTLKPAIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGISLVNEATFGCSCTDCFFQKCCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPDCPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYDNKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRTVCKCGAVTCRGYLN
" misc_feature <248..343 /gene="SUV39H2" /gene_synonym="KMT1B" /note="Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence...; Region: CHROMO; cd00024" /db_xref="CDD:28908" misc_feature order(260..262,266..268,275..277,287..289,299..301, 311..316) /gene="SUV39H2" /gene_synonym="KMT1B" /note="histone binding site; other site" /db_xref="CDD:28908" misc_feature 497..790 /gene="SUV39H2" /gene_synonym="KMT1B" /note="Pre-SET motif; Region: Pre-SET; pfam05033" /db_xref="CDD:203156" misc_feature 812..1183 /gene="SUV39H2" /gene_synonym="KMT1B" /note="SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; Region: SET; smart00317" /db_xref="CDD:197649" variation 331 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:148153307" variation 352 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:376764262" variation 354 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:140852434" variation 408 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:144521316" variation 412 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:3740112" variation 426..427 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="" /replace="c" /db_xref="dbSNP:35348245" variation 431 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:372163934" variation 443 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:201043867" variation 456 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:138508980" variation 464 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:45473500" variation 472 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:150726093" STS 545..1044 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="MARC_27758-27759:1034860367:1" /db_xref="UniSTS:269123" STS 556..879 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="ksks283" /db_xref="UniSTS:514323" variation 583 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:138078553" variation 609 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:149546848" variation 619 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:200539708" variation 626 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:376480219" variation 817 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:368991744" variation 845 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:375736366" variation 847 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:199654065" variation 883 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:144034230" exon 914..1060 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" variation 973 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:190174096" variation 985 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:183140822" variation 986 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:148667087" variation 1030 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:17353856" variation 1036 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:369186882" variation 1051 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:147278353" exon 1061..1190 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" variation 1105 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:61730323" variation 1130 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:369793867" exon 1191..3100 /gene="SUV39H2" /gene_synonym="KMT1B" /inference="alignment:Splign:1.39.8" variation 1266 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:199727444" variation 1276 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:144605484" variation 1292 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:201395473" variation 1316 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:375126181" variation 1352 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:368830300" variation 1388 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:113301024" variation 1409 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:373511332" variation 1424 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:11547181" variation 1445 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:373567048" variation 1456 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:180989547" variation 1460 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="" /replace="g" /db_xref="dbSNP:375028927" STS 1579..1700 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="RH48597" /db_xref="UniSTS:71892" variation 1637 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:116910335" variation 1650 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="c" /db_xref="dbSNP:75420442" polyA_signal 1812..1817 /gene="SUV39H2" /gene_synonym="KMT1B" variation 1831..1833 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="" /replace="aat" /db_xref="dbSNP:367684066" polyA_site 1832 /gene="SUV39H2" /gene_synonym="KMT1B" polyA_site 1848 /gene="SUV39H2" /gene_synonym="KMT1B" polyA_signal 1857..1862 /gene="SUV39H2" /gene_synonym="KMT1B" variation 1869..1872 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="" /replace="aatt" /db_xref="dbSNP:371874353" polyA_site 1874 /gene="SUV39H2" /gene_synonym="KMT1B" polyA_site 1885 /gene="SUV39H2" /gene_synonym="KMT1B" variation 1982 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:142967205" variation 2039 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:185218421" variation 2101 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:41284455" variation 2192 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:11594111" variation 2263 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:190438184" variation 2379 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:181251834" variation 2517 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:61843036" variation 2654 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:75516757" variation 2676 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:376829730" variation 2734 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:150828159" variation 2859 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:139176971" variation 2923 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:11259385" STS 2962..3044 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="L18426" /db_xref="UniSTS:34648" STS 2963..3042 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="D5S1597E" /db_xref="UniSTS:151019" STS 2964..3066 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="D11S2921" /db_xref="UniSTS:152074" STS 2966..3035 /gene="SUV39H2" /gene_synonym="KMT1B" /standard_name="D1S1423" /db_xref="UniSTS:149619" variation 3003 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="g" /replace="t" /db_xref="dbSNP:186353154" variation 3021 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="t" /db_xref="dbSNP:191603474" variation 3022 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="g" /db_xref="dbSNP:371491790" variation 3041 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="c" /replace="g" /db_xref="dbSNP:183557434" variation 3089 /gene="SUV39H2" /gene_synonym="KMT1B" /replace="a" /replace="t" /db_xref="dbSNP:79193913" ORIGIN
agtttgaatgaaagctctacaagatggcggcggtcggggccgaggcgcgaggaggtgaggctggagcgcggccccctcgccttccctgttcccagcttggtgtgtgccttgcctagtttcacttgatactcttcaggaattatgtagaaaagaaaagctcacatgtaaatcgattggaatcaccaaaaggaatctaaacaattatgaggtggaatacttgtgtgactacaaggtagtaaaggatatggaatattatcttgtaaaatggaaaggatggccagattctacaaatacttgggaacctttgcaaaatctgaagtgcccgttactgcttcagcaattctctaatgacaagcataattatttatctcaggtaaagaaaggcaaagcaataactccaaaagacaataacaaaactttgaaacctgccattgctgagtacattgtgaagaaggctaaacaaaggatagctctgcagagatggcaagatgaactcaacagaagaaagaatcataaaggaatgatatttgttgaaaatactgttgatttagagggcccaccttcagacttctattacattaacgaatacaaaccagctcctggaatcagcttagtcaatgaagctacctttggttgttcatgcacagattgcttctttcaaaaatgttgtcctgctgaagctggagttcttttggcttataataaaaaccaacaaattaaaatcccacctggtactcccatctatgaatgcaactcaaggtgtcagtgtggtcctgattgtcccaataggattgtacaaaaaggcacacagtattcgctttgcatctttcgaactagcaatggacgtggctggggtgtaaagacccttgtgaagattaaaagaatgagttttgtcatggaatatgttggagaggtaatcacaagtgaagaagctgaaagacgaggacagttctatgacaacaagggaatcacgtatctctttgatctggactatgagtctgatgaattcacagtggatgcggctcgatacggcaatgtgtctcattttgtgaatcacagctgtgacccaaatcttcaggtgttcaatgttttcattgataacctcgatactcgtcttccccgaatagcattgttttccacaagaaccataaatgctggagaagagctgacttttgattatcaaatgaaaggttctggagatatatcttcagattctattgaccacagcccagccaaaaagagggtcagaacagtatgtaaatgtggagctgtgacttgcagaggttacctcaactgaactttttcaggaaatagagctgatgattataatatttttttcctaatgttaacatttttaaaaatacatatttgggactcttattatcaaggttctacctatgttaatttacaattcatgtttcaagacatttgccaaatgtattaccgatgcctctgaaaagggggtcactgggtctcatagactgatatgaagtcgacatatttatagtgcttagagaccaaactaatggaaggcagactatttacagcttagtatatgtgtacttaagtctatgtgaacagagaaatgcctcccgtagtgtttgaaagcgttaagctgataatgtaattaacaactgctgagagatcaaagattcaacttgccatacacctcaaattcggagaaacagttaatttgggcaaatctacagttctgtttttgctactctattgtcattcctgtttaatactcactgtacttgtatttgagacaaataggtgatactgaattttatactgttttctacttttccattaaaacattggcacctcaatgataaagaaatttaaggtataaaattaaatgtaaaaattaatttcagcttcatttcgtatttcgaagcaatctagactgttgtgatgagtgtatgtctgaacctgtaattcttaaaagacttcttaatcttctagaagaaaaatctccgaagagctctctctagaagtccaaaatggctagccattatgcttctttgaaaggacatgataatgggaccaggatggttttttggagtaccaagcaaggggaatggagcactttaagggcgcctgttagtaacatgaattggaaatctgtgtcgagtacctctgatctaaacggtaaaacaagctgcctggagagcagctgtacctaacaatactgtaatgtacattaacattacagcctctcaatttcaggcaggtgtaacagttcctttccaccagatttaatatttttatacttcctgcaggttcttcttaaaaagtaatctatatttttgaactgatacttgttttatacataaattttttttagatgtgataaagctaaacttggccaaagtgtgtgcctgaattattagacctttttattagtcaacctacgaagactaaaatagaatatattagttttcaagggagtgggaggcttccaacatagtattgaatctcaggaaaaactattctttcatgtctgattctgagatttctaattgtgttgtgaaaatgataaatgcagcaaatctagctttcagtattcctaatttttacctaagctcattgctccaggctttgattacctaaaataagcttggataaaattgaaccaacttcaagaatgcagcacttcttaatctttagctctttcttgggagaagctagactttattcattatattgctatgacaacttcactctttcataatatataggataaattgtttacatgattggaccctcagattctgttaaccaaaattgcagaatggggggccaggcctgtgtggtggctcacacctgtgatcccagcactttgggaggctgaggtaggaggatcacgtgaggtcgggagttcaagaccagcctggccatcatggtgaaaccctgtctctactgaaaatacaaaaattagccgggcgtggtggcacacgcctgtagtcccagctactcaggaggctgaggcaggagaatcacttgaattcaggaggcggaggttgcagtgagccaagatcataccactgcactgcagcctgagtgacacagtaagactgtctccaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726): GeneID:79723 -> Molecular function: GO:0003682 [chromatin binding] evidence: IEA GeneID:79723 -> Molecular function: GO:0005515 [protein binding] evidence: IPI GeneID:79723 -> Molecular function: GO:0008270 [zinc ion binding] evidence: IEA GeneID:79723 -> Molecular function: GO:0046974 [histone methyltransferase activity (H3-K9 specific)] evidence: IDA GeneID:79723 -> Biological process: GO:0006333 [chromatin assembly or disassembly] evidence: IMP GeneID:79723 -> Biological process: GO:0006338 [chromatin remodeling] evidence: IDA GeneID:79723 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA GeneID:79723 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IEA GeneID:79723 -> Biological process: GO:0007140 [male meiosis] evidence: IEA GeneID:79723 -> Biological process: GO:0030154 [cell differentiation] evidence: IEA GeneID:79723 -> Cellular component: GO:0000775 [chromosome, centromeric region] evidence: IEA GeneID:79723 -> Cellular component: GO:0000785 [chromatin] evidence: IDA GeneID:79723 -> Cellular component: GO:0005720 [nuclear heterochromatin] evidence: IEA ANNOTATIONS from NCBI Entrez Gene (20130726): NP_001180354 -> EC 2.1.1.43
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.