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2020-10-24 07:30:45, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001190737            8507 bp    mRNA    linear   PRI 15-JUN-2013
DEFINITION  Homo sapiens nuclear factor I/B (NFIB), transcript variant 1, mRNA.
ACCESSION   NM_001190737
VERSION     NM_001190737.1  GI:299758475
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8507)
  AUTHORS   Ramanan,V.K., Risacher,S.L., Nho,K., Kim,S., Swaminathan,S.,
            Shen,L., Foroud,T.M., Hakonarson,H., Huentelman,M.J., Aisen,P.S.,
            Petersen,R.C., Green,R.C., Jack,C.R., Koeppe,R.A., Jagust,W.J.,
            Weiner,M.W. and Saykin,A.J.
  TITLE     APOE and BCHE as modulators of cerebral amyloid deposition: a
            florbetapir PET genome-wide association study
  JOURNAL   Mol. Psychiatry (2013) In press
   PUBMED   23419831
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 8507)
  AUTHORS   Ho,C.Y., Bar,E., Giannini,C., Marchionni,L., Karajannis,M.A.,
            Zagzag,D., Gutmann,D.H., Eberhart,C.G. and Rodriguez,F.J.
  TITLE     MicroRNA profiling in pediatric pilocytic astrocytoma reveals
            biologically relevant targets, including PBX3, NFIB, and METAP2
  JOURNAL   Neuro-oncology 15 (1), 69-82 (2013)
   PUBMED   23161775
  REMARK    GeneRIF: Increased expression of NF1B is associated with pilocytic
            astrocytoma.
REFERENCE   3  (bases 1 to 8507)
  AUTHORS   Persson,M., Andren,Y., Moskaluk,C.A., Frierson,H.F. Jr.,
            Cooke,S.L., Futreal,P.A., Kling,T., Nelander,S., Nordkvist,A.,
            Persson,F. and Stenman,G.
  TITLE     Clinically significant copy number alterations and complex
            rearrangements of MYB and NFIB in head and neck adenoid cystic
            carcinoma
  JOURNAL   Genes Chromosomes Cancer 51 (8), 805-817 (2012)
   PUBMED   22505352
  REMARK    GeneRIF: Explored copy number alterations rearrangements in adenoid
            cystic carcinoma. 86% of the tumors expressed MYB-NFIB fusion
            transcripts and 97% overexpressed MYB mRNA.
REFERENCE   4  (bases 1 to 8507)
  AUTHORS   Choi,J., Ababon,M.R., Matteson,P.G. and Millonig,J.H.
  TITLE     Cut-like homeobox 1 and nuclear factor I/B mediate ENGRAILED2
            autism spectrum disorder-associated haplotype function
  JOURNAL   Hum. Mol. Genet. 21 (7), 1566-1580 (2012)
   PUBMED   22180456
  REMARK    GeneRIF: The data demonstrates that the autism spectrum
            disorder-associated A-C intronic haplotype of the ENGRAILED2 gene
            is a transcriptional activator, and both CUX1 and NFIB mediate this
            activity.
REFERENCE   5  (bases 1 to 8507)
  AUTHORS   Mitani,Y., Rao,P.H., Futreal,P.A., Roberts,D.B., Stephens,P.J.,
            Zhao,Y.J., Zhang,L., Mitani,M., Weber,R.S., Lippman,S.M., Caulin,C.
            and El-Naggar,A.K.
  TITLE     Novel chromosomal rearrangements and break points at the t(6;9) in
            salivary adenoid cystic carcinoma: association with MYB-NFIB
            chimeric fusion, MYB expression, and clinical outcome
  JOURNAL   Clin. Cancer Res. 17 (22), 7003-7014 (2011)
   PUBMED   21976542
  REMARK    GeneRIF: study concludes conclude that: t(6;9) results in complex
            genetic and molecular alterations in adenoid cystic carcinoma
            (ACC); MYB-NFIB gene fusion may not always be associated with
            chimeric transcript formation; noncanonical MYB-NFIB gene fusions
            occur in a subset of tumors; high MYB expression correlates with
            worse patient survival
REFERENCE   6  (bases 1 to 8507)
  AUTHORS   Mukhopadhyay,S.S. and Rosen,J.M.
  TITLE     The C-terminal domain of the nuclear factor I-B2 isoform is
            glycosylated and transactivates the WAP gene in the JEG-3 cells
  JOURNAL   Biochem. Biophys. Res. Commun. 358 (3), 770-776 (2007)
   PUBMED   17511965
  REMARK    GeneRIF: C-terminal domain of the nuclear factor I-B2 isoform is
            glycosylated and transactivates the WAP gene in tumor cells
REFERENCE   7  (bases 1 to 8507)
  AUTHORS   Sheeter,D., Du,P., Rought,S., Richman,D. and Corbeil,J.
  TITLE     Surface CD4 expression modulated by a cellular factor induced by
            HIV type 1 infection
  JOURNAL   AIDS Res. Hum. Retroviruses 19 (2), 117-123 (2003)
   PUBMED   12639247
  REMARK    GeneRIF: expression of NFI-B2 impairs CD4 transcription on
            CDd4-positive primary T-lymphocytes and cell lines in HIV-1
            infection
REFERENCE   8  (bases 1 to 8507)
  AUTHORS   Geurts,J.M., Schoenmakers,E.F., Roijer,E., Astrom,A.K., Stenman,G.
            and van de Ven,W.J.
  TITLE     Identification of NFIB as recurrent translocation partner gene of
            HMGIC in pleomorphic adenomas
  JOURNAL   Oncogene 16 (7), 865-872 (1998)
   PUBMED   9484777
REFERENCE   9  (bases 1 to 8507)
  AUTHORS   Liu,Y., Bernard,H.U. and Apt,D.
  TITLE     NFI-B3, a novel transcriptional repressor of the nuclear factor I
            family, is generated by alternative RNA processing
  JOURNAL   J. Biol. Chem. 272 (16), 10739-10745 (1997)
   PUBMED   9099724
REFERENCE   10 (bases 1 to 8507)
  AUTHORS   Qian,F., Kruse,U., Lichter,P. and Sippel,A.E.
  TITLE     Chromosomal localization of the four genes (NFIA, B, C, and X) for
            the human transcription factor nuclear factor I by FISH
  JOURNAL   Genomics 28 (1), 66-73 (1995)
   PUBMED   7590749
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL136366.24, BX648845.1, AL441963.7 and AI140312.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and it encodes the longest protein (isoform 1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX648845.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025081, ERS025083 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-565               AL136366.24        90547-91111         c
            566-1097            AL136366.24        84054-84585         c
            1098-1341           BX648845.1         1098-1341
            1342-1460           AL441963.7         83224-83342         c
            1461-2002           BX648845.1         1461-2002
            2003-8004           AL441963.7         18860-24861         c
            8005-8507           AI140312.1         3-505               c
FEATURES             Location/Qualifiers
     source          1..8507
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9p24.1"
     gene            1..8507
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /note="nuclear factor I/B"
                     /db_xref="GeneID:4781"
                     /db_xref="HGNC:7785"
                     /db_xref="MIM:600728"
     exon            1..565
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    524..526
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /note="upstream in-frame stop codon"
     CDS             536..2020
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     nuclear factor 1 B-type; nuclear factor 1/B; TGGCA-binding
                     protein; CCAAT-box-binding transcription factor"
                     /codon_start=1
                     /product="nuclear factor 1 B-type isoform 1"
                     /protein_id="NP_001177666.1"
                     /db_xref="GI:299758476"
                     /db_xref="CCDS:CCDS55291.1"
                     /db_xref="GeneID:4781"
                     /db_xref="HGNC:7785"
                     /db_xref="MIM:600728"
                     /translation="
MMYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLAYYVQEQDSGQSGSPSHNDPAKNPPGYLEDSFVKSGVFNVSELVRVSRTPITQGTGVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPSSPAAGSRTWHERDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQTSQPNGSGQVVGKVPGHFTPVLAPSPHPSAVRPVTLSMTDTKPITTSTEAYTASGTSQANRYVGLSPRDPSFLHQQQSWYLG
"
     misc_feature    539..541
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N-acetylmethionine; propagated from
                     UniProtKB/Swiss-Prot (O00712.2); acetylation site"
     misc_feature    545..676
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /note="Nuclear factor I protein pre-N-terminus; Region:
                     NfI_DNAbd_pre-N; pfam10524"
                     /db_xref="CDD:151076"
     misc_feature    740..1054
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /note="N-terminal Mad Homology 1 (MH1) domain; Region:
                     MH1; cl00055"
                     /db_xref="CDD:206806"
     misc_feature    1160..2017
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /note="CTF/NF-I family transcription modulation region;
                     Region: CTF_NFI; pfam00859"
                     /db_xref="CDD:144451"
     misc_feature    1325..1327
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (O00712.2); phosphorylation site"
     misc_feature    1469..1471
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (O00712.2); phosphorylation site"
     misc_feature    1517..1519
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (O00712.2); phosphorylation site"
     misc_feature    1532..1534
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (O00712.2); phosphorylation site"
     exon            566..1097
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /inference="alignment:Splign:1.39.8"
     variation       954
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:11543132"
     exon            1098..1151
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /inference="alignment:Splign:1.39.8"
     exon            1152..1220
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /inference="alignment:Splign:1.39.8"
     exon            1221..1341
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /inference="alignment:Splign:1.39.8"
     STS             1316..2276
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /standard_name="Nfib"
                     /db_xref="UniSTS:527449"
     exon            1342..1460
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /inference="alignment:Splign:1.39.8"
     exon            1461..1595
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /inference="alignment:Splign:1.39.8"
     exon            1596..1780
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /inference="alignment:Splign:1.39.8"
     exon            1781..1919
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /inference="alignment:Splign:1.39.8"
     exon            1920..2002
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /inference="alignment:Splign:1.39.8"
     exon            2003..8486
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /inference="alignment:Splign:1.39.8"
     STS             2015..2243
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /standard_name="RH80854"
                     /db_xref="UniSTS:89539"
     STS             2095..2594
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /standard_name="MARC_17865-17866:1025013775:1"
                     /db_xref="UniSTS:268427"
     variation       2511
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1804815"
     variation       2559
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:7858"
     STS             3285..3486
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /standard_name="EST12E1"
                     /db_xref="UniSTS:263076"
     variation       3535
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:199841856"
     variation       4745
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:484555"
     STS             5371..5449
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /standard_name="D8S1564E"
                     /db_xref="UniSTS:153761"
     STS             5396..5551
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /standard_name="RH78074"
                     /db_xref="UniSTS:14692"
     STS             5554..5811
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /standard_name="A004O32"
                     /db_xref="UniSTS:83500"
     STS             6362..6546
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /standard_name="A006V16"
                     /db_xref="UniSTS:41122"
     variation       7120
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:506115"
     STS             7150..7335
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /standard_name="D9S1065E"
                     /db_xref="UniSTS:151282"
     STS             7524..7650
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /standard_name="WI-14235"
                     /db_xref="UniSTS:80885"
     variation       8320
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1059606"
     STS             8340..8465
                     /gene="NFIB"
                     /gene_synonym="CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B;
                     NFI-RED; NFIB2; NFIB3"
                     /standard_name="D9S2012"
                     /db_xref="UniSTS:82852"
ORIGIN      
gggctgtaaccttgaactttcccagcgcggtgacacattctccccgctctccctcccgcccgcccgctcgccctcctgcgccctcccgcgcccccctccccgccttttttgaaaaagcattttaccaccaaccaccaccccaatccaacccacaccgaaccttcgcgcaccccctacaccccaacaacaacaacaactgcaaaatagaaaacaaatccccaaacccaggcgaaaagcagccaacaccggcggcggcggcggcctcggcaagcacggccagcgcgctcggactgcaagagggttaaaagtgtagattggatttcacccctggaaatctagcacgccgagtgaacttgaatctttggctatttaaggaggactgggtttgttgtgaagttgcggtgatccagcgcagagccccgtcctgattgatcgcatcgcggggctcagatgactgtaaaatgaatagatgaaattcttgcttctcgaagattttcttgggcatctcccggaaagtgcgttttaaggcgaagtcatgatgtattctcccatctgtctcactcaggatgaatttcacccattcatcgaggcacttcttccacatgtccgtgcaattgcctatacttggttcaacctgcaggctcgaaaacgcaagtactttaaaaagcatgagaagcgaatgtcaaaggatgaagaaagagcagtcaaagatgagcttctcagtgaaaagcctgaaatcaaacagaagtgggcatccaggctccttgccaaactgcgcaaagatattcgccaggagtatcgagaggactttgtgctcaccgtgactggcaagaagcacccgtgctgtgtcttatccaatcccgaccagaagggtaagattaggagaatcgactgcctgcgacaggcagacaaagtctggcgtctggatctagtcatggtgatcctgttcaaaggcatccccttggaaagtaccgatggagagcggctcatgaaatccccacattgcacaaacccagcactttgtgtccagccacatcatatcacagtatcagttaaggagcttgatttgtttttggcatactacgtgcaggagcaagattctggacaatcaggaagtccaagccacaatgatcctgccaagaatcctccaggttaccttgaggatagttttgtaaaatctggagtcttcaatgtatcagaacttgtaagagtatccagaacgcccataacccagggaactggagtcaacttcccaattggagaaatcccaagccaaccatactatcatgacatgaactcgggggtcaatcttcagaggtctctgtcttctccaccaagcagcaaaagacccaaaactatatccatagatgaaaatatggaaccaagtcctacaggagacttttacccctctccaagttcaccagctgctggaagtcgaacatggcacgaaagagatcaagatatgtcttctccgactactatgaagaagcctgaaaagccattgttcagctctgcatctccacaggattcttccccaagactgagcactttcccccagcaccaccatcccggaatacctggagttgcacacagtgtcatctcaactcgaactccacctccaccttcaccgttgccatttccaacacaagctatccttcctccagccccatcgagctacttttctcatccaacaatcagatatcctccccacctgaatcctcaggatactctgaagaactatgtaccttcttatgacccatccagtccacaaaccagccagcctaacggcagtggtcaagtagtagggaaagtgcctggccatttcactcctgtcttggcaccctctccccatcccagtgcagtgcgacctgtgaccctgagcatgacagatactaaacccatcactacatccactgaagcctacacagcctcaggcacatctcaagccaatcgatatgtgggactaagcccaagagacccatccttcctacatcagcaacagtcctggtacctgggctagcttggttcctttccaagtgtcaaataggacacccatcttaccggccaatgtccaaaattacggtttgaacataattggagaacctttccttcaagcagaaacaagcaactgagggaaaaagaaacacaacaatagtttaagaaattttttttttaaataaaaaaaaaggaaaagaggaagactggacaaaacaacacaaaggcagaaaggaaagaaactgaagaaagaagataatagaccagcaattgcagcacttacaatcactaattcccttaaggttgaaactgtaatgacataaaaagggtcgatgatatttcactgatggtagatcgcagcccctgcaacgtagcctttgttacatgaagtccgctgggaaatagatgttctgtctctatgacaatatattttaactgactttctagatgccttaatatttgcatgataagctagttttattggtttagtattcttgttgtttacgcatggaatcactattcctggttatctcaccaacgaaggctaggaggcggcgtcagaggtgctgggtgacagagccatgagccagccattttataagcactctgatttctaaaagttaaaaaaaatatatgaaatctctgtagcctttagttatcagtacagatttattaaatttcggcccttaacccagccttttccagtgtgtaacccagtttgaaatcttaaaaaaagaaaaaatgaaaaaaaaaggaaaaaaagaaaaaaggaaaaaaacagtttgaacacaaaggctctatggaagaaatgcctctatgtaggtgaagtgttctctctgcatgcaacagtaaaaattaatataatattttccccacaaaagaaacacttaacagaggcaagtgcaatttataaatttatatctaaaggggaatcatgattataagtccttcagcccttggactctaaattgaggggattaaaaagaatttaaaataattttgaacgaatttattttcccctcagtttttgagggcattaaaaaggcattaaatcaagacaaatcatgtgcttgagaaaaataaaattaatgaaaacacagcacttatgttggtttagctgcagcctccttggaggtagaatttatttatttaaaattactggttgcatcaagaacccatagggtgtacaaaaggttctataaaatctgcattatagagacaaagaggcaggcaaatccatgtcacaagggtaaagcttacagtttacaaactgggaacgccagggtgtaggatataaaaacgcactcttgagaaaacaaatgtaatcagggtgctgaaaacttgcatggtgctttcagacattagccttgttcaacaaatttcttgtattgacagatccatagtgtgcatgggcagacacattttgcctctatgtctcttaaaattttaattaaaaatactctttccagtaatcctaatttgcacgaagatataatgtccacattacgtgccttgccttgaaatctaaaaaacaaaaaacaaaaaaaaaaaaacaaaaaaatacaacaaagtgacatcactacacttgttttgctgcatttattatcattttaaatctttaccatttttatgacaaaatattttgtactccagacgaagaaaaatgtgtgacatcatggattttttagacagttatacctttatctcacatttataaagcatatcatggctgtgtatagttgccgcttaaaaattgtaatcgaccagcaatattttcagtattttggtgtttttttctattaacctttcatgtttttcatcttccaattaatatttgggggggaggggtttcaaatttatacgaattatgcaataccaagttttgcctatgtaggtagtgcttttagctgtattggttattataggtaagtacacagatttaaaaaaaaaataatgtatgcttttttgtttgtttgtttgttttaattgaccaaagtgggtactgctatttttgcagtgtgatgaggtccttttgtgtactgagagatggacaggggattttttttaatatacatatatatatattctggggtgggtgggaggatttttaacactttgcagtgtagctgtgaagcagtgcaccctgagatgggcctgggctgcaaagcgactgttctgcctactgtgacaaacttcaacttacacaggttcccctctctaacttcccacctgggttgcaagctgaactcattactggttttcataacaacacaatagtaagaacaagcaaacacaacaaattctcctggaggcagacttggcttaaaaaggcagacttggcttggtgatagtttttcttgaaagttccagatccacagtggagagtgagcctgtctcatatttggcaaaaatatttgttgaaatgtccacataggggatgttggatgtttaacacttttgagagtttaacacatgaatattctttctcctagaaaacacattagacctgttggagggagtctcccgtattccttttctgccacttttcgtccccatttcatttcattaatgataggatatgatttacctgtgacttactacttcaaatggatggcagtgcacttggatttttttttaatatccagaagattgaacagagggttgctattgttgaatgtatttggactgatagattaaaatcaaagttcaatttttaaggaacaaaaaagtaaatcctgttttcattttatctccccttttaaaactgagaaccagagcagaagggaaatatagaattttaagcaattaatcttcctgtggatgaattaaacccattagatgctgatgggatttttttaaggaatggtaccttaactatatatttgatttcgtttcccctgagggctagaggctgaatggaggctggttttattttgcctttccctcaccgcccagtcccattgagtgtattcattactagaaggaaaatctttcagaattggtgacacatggtaggctgtcttaaggagtcccctggcccccttcccctaggccatggcctaataaaataaactgtcaattgttctcacagcatatcatttaataatgaatactttagaacaatgcttatgggctggagaattgtatttgattagcccattcagtttgatagcccaaatgctgaacagcacagcgggatcctagcagtgcaagttcaaaagtaagtccaatcatttctgtgatactcgccctggtagcaaacagatcatctcagccaagctcttcatgtatctttgacctattaggtgaacaaatgaacctcacaggacacacagtattttttaaaggcagactcgctctcttttttgccagtgagcagttctagctaaccaagttacacactgtgggtattcctgcctgcctcttgaatacaaaggcctagttcaagtgttgctttttttatttcaaatcaattttttcttctttcctttttgagataaaactattaaaagtactactatatatataaaatctcaaatcaacttttcggcctcctcctcgtgtaccaggaagtatattctgacgaagggccccacttttgcaggtcttgcacgcccctcccttacccagaactgcagagcttcaggatggcgaaggtcacccaagggcatgagtagggagtggtgtctccaaccatcagttccgtggcactgttcagcctttgtgtgctgccctgccacccaccactcacagtgcctctgaagcgtgttacccctggagtgacgtgagcatttgaggcttgtctaaggaaaaaaataaaaggcagtgaaggagactgtacataaagacatggcaaaaatcttaattatagcaatatagttatcgggtaatgttcgggtgggcagctccattaaaaaatatgtgaatgaatctgtgaagctgcaagtagcgagaagagcgaaaggtcttcttaatgaaccgcctaccttgtagacagtaatttgtacactgtatagttttgttaagaattttttttaaattaaaattcccatgtttgtaaagctaactttttaacaattataatggaactatatgttgtttccatttttaaagtaaacaagaatattccttgtttagagactggacttgagttaaaactctccagtctcttaagttatgtattaaaaagaaaatctgtccatgttaggagttatttcacagattcctgtgcttgaaaagcataggatactaatcctttaaaaaagtgtaaatggagaaaagttatattttatgaaggttattttgttgtatttagtattggaaaagttggtttccagagcatttcagaatgtcgaagcaccactgtctttttattagtatatacggcctttagcaaaagtttttgtgattgttacgtgatggtatttaaggttaagtttcacagagcattcaggataggcagaaaactaaaacagtgctatgtctcacataacgtgtcctcagggagcagaatcttggatttgtgacttgtagcttcataaggactcaacgaaagagattgcacagggacatcttcagcggtgtgacagcaggacatgttctttacctagattcaaattctatgtactgtgtgaaatgatgaaggctgcagaaagttatcccatattcagtgtacagtattcatttttaatgaaacaactctacaatattgctggcagataggccccaagcatgacattcaatatagtttacatgttcctgtcaaggtcttttgttaacattaaccagctgcatgctttctggactttaagaaattgggtttctatagaaaactttttttttttttttttttttaatgtgcaggctattcaagttcaatagtaaaagctcaaaaatgaatgttctactccatgctgaaggagctgaaagctgccttcttcatattttgcactttctggtagttcccctgttttttctaattccctaaaattgtgtgggtggagtggagccctgcagttggggggtaacatggaccactgattttgccctttgaccctgcacaatgacctttgcatcagccaaactcattgccatgacaactctttgtactgtgtccgtgccacagatctgttggtcacattgttaatagtaaaggggacaagttggagacggtcaatttttacattttttgttgcaattttttcttcaatggttgtaagtagtttttttttttttttaataataaaagggttcactagttaatactctagaaatatctgtgtgttgcaattcaaatgtatgttgagattgtgaaaagcgcttcagtgccactagcttaccggtacactagactaagcccttgatgacttattgcatgatacagtaccaggaacaacaggtggcctaaatacatgaaaagcagtgtaagctagtgacactaaagccagtcttgtattactgtatttttgacagaatggttttgaaaactgtgctacagggactgatgtggcaaatatatctctttatgcagaaggaagtctttttttttcttttttttttttttaagaagtatggctttttatgcatccttcatcgagggcattgaagttgcatggactgataaaagttgatgcaaaacaagaaagaaacaaacaaaaaaaaaaaaccagcaaaatgtttaccaaaaaactcaaacaaatgagcagtgcctgttcaatttcacagtctctgttgagttcagttgtaaatatgtttcaaatgacattttcttgggaaaaaaaatctctacaacattgtagaatgtgaggggtaactacatcccaggcataggtttctcaaagctgcagtagattatgtcttcatcaagctgttaatttgtgcttatatcatatagaacttttagcatcctgggaagagctgcccccacctcaatgatatttctctgagaacaacttttgtaggactgtgtgtttctttagatacatttagtacaactgtaggtgacgagtagtcagttattgcttgctagctacacaccagggttgatccattttaaaacttttggcattttgtcctcatgggccataaatacagaaccttgtattttaattaaatttttttacaaaaggaggcacatgcacaatctccatgtaacaaacctttagcagtaggatgtattatacgacagttacttaatttctagagttcaggcctctgggatcaaccccagactgggccagaatgttagtgaaggttttattgtgcccggttggaggataacgttctttgggtactttttgtgggttgcaaatgaactcaattgccacaagttttaaactggtgtaaatcaagcttgacttaatgtgattgttactgttatatccagcctatactgctagcagctgctcatactgcagtcaattactggaagcggatatatttcctatgcaaaaactgtttaaacaataaaatgagctatgctacagactctgaaaaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:4781 -> Molecular function: GO:0000981 [sequence-specific DNA binding RNA polymerase II transcription factor activity] evidence: IDA
            GeneID:4781 -> Molecular function: GO:0001077 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription] evidence: IEA
            GeneID:4781 -> Molecular function: GO:0001106 [RNA polymerase II transcription corepressor activity] evidence: IDA
            GeneID:4781 -> Molecular function: GO:0003677 [DNA binding] evidence: IDA
            GeneID:4781 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IDA
            GeneID:4781 -> Biological process: GO:0002062 [chondrocyte differentiation] evidence: ISS
            GeneID:4781 -> Biological process: GO:0006260 [DNA replication] evidence: IEA
            GeneID:4781 -> Biological process: GO:0006366 [transcription from RNA polymerase II promoter] evidence: IDA
            GeneID:4781 -> Biological process: GO:0010001 [glial cell differentiation] evidence: ISS
            GeneID:4781 -> Biological process: GO:0021740 [principal sensory nucleus of trigeminal nerve development] evidence: ISS
            GeneID:4781 -> Biological process: GO:0021960 [anterior commissure morphogenesis] evidence: ISS
            GeneID:4781 -> Biological process: GO:0030902 [hindbrain development] evidence: IEA
            GeneID:4781 -> Biological process: GO:0043392 [negative regulation of DNA binding] evidence: IDA
            GeneID:4781 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IDA
            GeneID:4781 -> Biological process: GO:0060486 [Clara cell differentiation] evidence: ISS
            GeneID:4781 -> Biological process: GO:0060509 [Type I pneumocyte differentiation] evidence: ISS
            GeneID:4781 -> Biological process: GO:0060510 [Type II pneumocyte differentiation] evidence: ISS
            GeneID:4781 -> Biological process: GO:0061141 [lung ciliated cell differentiation] evidence: ISS
            GeneID:4781 -> Biological process: GO:0071679 [commissural neuron axon guidance] evidence: ISS
            GeneID:4781 -> Biological process: GO:2000791 [negative regulation of mesenchymal cell proliferation involved in lung development] evidence: ISS
            GeneID:4781 -> Biological process: GO:2000795 [negative regulation of epithelial cell proliferation involved in lung morphogenesis] evidence: ISS
            GeneID:4781 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:4781 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
            GeneID:4781 -> Cellular component: GO:0044300 [cerebellar mossy fiber] evidence: ISS

by @meso_cacase at DBCLS
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