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2024-04-20 00:18:32, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001177718 4054 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens Kruppel-like factor 11 (KLF11), transcript variant 3,
mRNA.
ACCESSION NM_001177718
VERSION NM_001177718.1 GI:295148162
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4054)
AUTHORS Fan,Y., Guo,Y., Zhang,J., Subramaniam,M., Song,C.Z., Urrutia,R. and
Chen,Y.E.
TITLE Kruppel-like factor-11, a transcription factor involved in diabetes
mellitus, suppresses endothelial cell activation via the nuclear
factor-kappaB signaling pathway
JOURNAL Arterioscler. Thromb. Vasc. Biol. 32 (12), 2981-2988 (2012)
PUBMED 23042817
REMARK GeneRIF: Kruppel-like factor-11, a transcription factor involved in
diabetes mellitus, suppresses endothelial cell activation via the
nuclear factor-kappaB signaling pathway.
REFERENCE 2 (bases 1 to 4054)
AUTHORS Faryna,M., Konermann,C., Aulmann,S., Bermejo,J.L., Brugger,M.,
Diederichs,S., Rom,J., Weichenhan,D., Claus,R., Rehli,M.,
Schirmacher,P., Sinn,H.P., Plass,C. and Gerhauser,C.
TITLE Genome-wide methylation screen in low-grade breast cancer
identifies novel epigenetically altered genes as potential
biomarkers for tumor diagnosis
JOURNAL FASEB J. 26 (12), 4937-4950 (2012)
PUBMED 22930747
REMARK GeneRIF: Data indicate that median methylation levels of BCAN,
HOXD1, KCTD8, KLF11, NXPH1, POU4F1, SIM1, and TCF7L1 were >/=30%
higher than in normal samples, representing potential biomarkers
for tumor diagnosis.
REFERENCE 3 (bases 1 to 4054)
AUTHORS Perakakis,N., Danassi,D., Alt,M., Tsaroucha,E., Mehana,A.E.,
Rimmer,N., Laubner,K., Wang,H., Wollheim,C.B., Seufert,J. and
Path,G.
TITLE Human Kruppel-like factor 11 differentially regulates human insulin
promoter activity in beta-cells and non-beta-cells via p300 and
PDX1 through the regulatory sites A3 and CACCC box
JOURNAL Mol. Cell. Endocrinol. 363 (1-2), 20-26 (2012)
PUBMED 22801105
REMARK GeneRIF: KLF11 has a role in fine-tuning insulin transcription in
certain cellular situations rather than representing a major
transcriptional activator or repressor of the insulin gene.
REFERENCE 4 (bases 1 to 4054)
AUTHORS Grunewald,M., Johnson,S., Lu,D., Wang,Z., Lomberk,G., Albert,P.R.,
Stockmeier,C.A., Meyer,J.H., Urrutia,R., Miczek,K.A., Austin,M.C.,
Wang,J., Paul,I.A., Woolverton,W.L., Seo,S., Sittman,D.B. and
Ou,X.M.
TITLE Mechanistic role for a novel glucocorticoid-KLF11 (TIEG2) protein
pathway in stress-induced monoamine oxidase A expression
JOURNAL J. Biol. Chem. 287 (29), 24195-24206 (2012)
PUBMED 22628545
REMARK GeneRIF: KLF11 is an MAO A regulator and is produced in response to
neuronal stress, which transcriptionally activates MAO A.
REFERENCE 5 (bases 1 to 4054)
AUTHORS Seo,S., Lomberk,G., Mathison,A., Buttar,N., Podratz,J., Calvo,E.,
Iovanna,J., Brimijoin,S., Windebank,A. and Urrutia,R.
TITLE Kruppel-like factor 11 differentially couples to histone
acetyltransferase and histone methyltransferase chromatin
remodeling pathways to transcriptionally regulate dopamine D2
receptor in neuronal cells
JOURNAL J. Biol. Chem. 287 (16), 12723-12735 (2012)
PUBMED 22375010
REMARK GeneRIF: Here we report the characterization of two antagonistic,
chromatin-mediated mechanisms by which KLF11 regulated the
transcription of the dopamine D2 receptor.
REFERENCE 6 (bases 1 to 4054)
AUTHORS Jia,L., Young,M.F., Powell,J., Yang,L., Ho,N.C., Hotchkiss,R.,
Robey,P.G. and Francomano,C.A.
TITLE Gene expression profile of human bone marrow stromal cells:
high-throughput expressed sequence tag sequencing analysis
JOURNAL Genomics 79 (1), 7-17 (2002)
PUBMED 11827452
REFERENCE 7 (bases 1 to 4054)
AUTHORS Zhang,J.S., Moncrieffe,M.C., Kaczynski,J., Ellenrieder,V.,
Prendergast,F.G. and Urrutia,R.
TITLE A conserved alpha-helical motif mediates the interaction of
Sp1-like transcriptional repressors with the corepressor mSin3A
JOURNAL Mol. Cell. Biol. 21 (15), 5041-5049 (2001)
PUBMED 11438660
REFERENCE 8 (bases 1 to 4054)
AUTHORS Scohy,S., Gabant,P., Van Reeth,T., Hertveldt,V., Dreze,P.L., Van
Vooren,P., Riviere,M., Szpirer,J. and Szpirer,C.
TITLE Identification of KLF13 and KLF14 (SP6), novel members of the
SP/XKLF transcription factor family
JOURNAL Genomics 70 (1), 93-101 (2000)
PUBMED 11087666
REFERENCE 9 (bases 1 to 4054)
AUTHORS Asano,H., Li,X.S. and Stamatoyannopoulos,G.
TITLE FKLF, a novel Kruppel-like factor that activates human embryonic
and fetal beta-like globin genes
JOURNAL Mol. Cell. Biol. 19 (5), 3571-3579 (1999)
PUBMED 10207080
REFERENCE 10 (bases 1 to 4054)
AUTHORS Cook,T., Gebelein,B., Mesa,K., Mladek,A. and Urrutia,R.
TITLE Molecular cloning and characterization of TIEG2 reveals a new
subfamily of transforming growth factor-beta-inducible Sp1-like
zinc finger-encoding genes involved in the regulation of cell
growth
JOURNAL J. Biol. Chem. 273 (40), 25929-25936 (1998)
PUBMED 9748269
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BG701929.1, BC074922.2,
AC104794.4, BC063286.1 and AI755210.1.
Summary: The protein encoded by this gene is a zinc finger
transcription factor that binds to SP1-like sequences in epsilon-
and gamma-globin gene promoters. This binding inhibits cell growth
and causes apoptosis. Defects in this gene are a cause of
maturity-onset diabetes of the young type 7 (MODY7). Three
transcript variants encoding two different isoforms have been found
for this gene. [provided by RefSeq, Apr 2010].
Transcript Variant: This variant (3) differs in the 5' UTR and
coding sequence compared to variant 1. The resulting isoform (b) is
shorter at the N-terminus compared to isoform a. Variants 2 and 3
both encode the same isoform (b).
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AK302880.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025084 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-693 BG701929.1 8-700
694-1737 BC074922.2 561-1604
1738-3557 AC104794.4 34491-36310
3558-3833 BC063286.1 3556-3831
3834-4054 AI755210.1 1-221 c
FEATURES Location/Qualifiers
source 1..4054
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p25"
gene 1..4054
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="Kruppel-like factor 11"
/db_xref="GeneID:8462"
/db_xref="HGNC:11811"
/db_xref="MIM:603301"
exon 1..207
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/inference="alignment:Splign:1.39.8"
variation 37
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:116412095"
variation 89..90
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="g"
/db_xref="dbSNP:76971231"
variation 149
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:188375369"
variation 161
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:139688148"
variation 182
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:368878946"
exon 208..477
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/inference="alignment:Splign:1.39.8"
variation 214
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200094318"
CDS 217..1704
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="isoform b is encoded by transcript variant 3;
krueppel-like factor 11; TIEG-2; TGFB-inducible early
growth response protein 2; transforming growth
factor-beta-inducible early growth response protein 2"
/codon_start=1
/product="Krueppel-like factor 11 isoform b"
/protein_id="NP_001171189.1"
/db_xref="GI:295148163"
/db_xref="CCDS:CCDS54333.1"
/db_xref="GeneID:8462"
/db_xref="HGNC:11811"
/db_xref="MIM:603301"
/translation="
MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQRSQKGDLLRIRPLTPVSDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTATDVLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTGESPAACFPTIQTPDCRLSDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGWPGAVQTCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLPAFLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAGNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIASAESPGSPLVSMPASA
"
misc_feature 1342..>1512
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="FOG: Zn-finger [General function prediction only];
Region: COG5048"
/db_xref="CDD:34653"
misc_feature 1393..1476
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="Zinc-finger double domain; Region: zf-H2C2_2;
pfam13465"
/db_xref="CDD:205643"
misc_feature 1483..1554
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="Zinc-finger double domain; Region: zf-H2C2_2;
pfam13465"
/db_xref="CDD:205643"
misc_feature 1528..1593
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="Zinc finger, C2H2 type; Region: zf-C2H2; cl15478"
/db_xref="CDD:210117"
variation 217
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:373697732"
variation 233
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:367566983"
variation 246
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:140643007"
variation 251
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:150096859"
variation 255
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:146577005"
variation 258
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:371327904"
variation 306
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:138710480"
STS 321..453
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/standard_name="RH78629"
/db_xref="UniSTS:80550"
variation 342
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:201555141"
variation 350
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:35927125"
variation 367
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:202142040"
variation 384
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:373935239"
variation 390
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:144083374"
variation 406
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200260496"
variation 409
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:76059450"
variation 440
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:146264648"
exon 478..1423
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/inference="alignment:Splign:1.39.8"
variation 478
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="t"
/db_xref="dbSNP:55653873"
variation 523
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:201792575"
variation 536
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:61755332"
variation 543
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:199941261"
variation 572
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:139111425"
variation 575
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:145933214"
variation 594
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:113903638"
variation 602
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:148968483"
variation 612
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:368067336"
variation 616
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:147735654"
variation 621
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:373126146"
variation 651
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:146462049"
variation 666
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:377399356"
variation 687
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:200997824"
variation 695
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:140504133"
variation 697
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:138601862"
variation 706
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:146238335"
variation 708
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:142659789"
variation 711
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:142266428"
variation 742
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:368982748"
variation 762
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:150737124"
variation 773
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:145588324"
variation 808
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:374436407"
variation complement(824)
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:34336420"
variation 836
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:148922317"
variation 838
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:200061013"
variation 844
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200561467"
variation 854
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:370039403"
variation 862
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:373828519"
variation 867
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:372266786"
variation 922
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:374251576"
variation 927
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:372404632"
variation 947
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:148123124"
variation 971
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:145504876"
variation 976
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:368207952"
variation 986
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:142673414"
variation 1016
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:372404152"
variation 1035
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:149235463"
variation 1041
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:201595721"
variation 1075
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200635526"
variation 1085
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:182304641"
variation 1117
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:377198797"
variation 1118
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:144431930"
variation 1120
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:368577352"
variation 1137
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:143517559"
variation 1139
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:144949098"
variation 1152
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:371589306"
variation 1157
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:151317435"
variation 1159
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:375265808"
variation 1167
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:369681560"
variation 1189
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:373173330"
variation 1204
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:121912645"
variation 1213
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:199649394"
variation 1215
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:145193520"
variation 1223
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:141318309"
variation 1242
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:146486664"
variation 1248
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:371102481"
variation 1261
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:372514890"
variation 1267
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:144897109"
variation 1283
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:141324729"
variation 1285
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:201432055"
variation 1295
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:370236540"
variation 1296
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:137865082"
variation 1298
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:35476458"
variation 1302
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:199624763"
variation 1326
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:117449189"
variation 1350
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:11687357"
variation 1365
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:201561310"
variation 1370
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:34762805"
variation 1411
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:369331650"
exon 1424..4033
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/inference="alignment:Splign:1.39.8"
variation 1475
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:369814305"
variation 1527
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:373796305"
variation 1547
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:199770737"
variation 1558
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:200532025"
variation 1559
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:142970758"
variation 1563
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:374953405"
variation 1594
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:151292984"
variation 1598
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:369974149"
variation 1613
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:201735305"
variation 1667
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:377358836"
variation 1668
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:36091043"
variation 1747
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:75910133"
variation 1751
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:370864119"
variation 1811
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:140559044"
variation 1898
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:76220150"
variation 1920
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:199892235"
variation 1921..1922
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="t"
/replace="tt"
/db_xref="dbSNP:34206941"
variation 1921
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:201145049"
variation 1922
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:112893539"
variation 1932
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:78254957"
variation 1939
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:150051327"
variation 1945
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:191010106"
variation 1959
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:111703851"
variation 1966
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:147746428"
variation 2115
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:183232432"
variation 2139
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:72786612"
variation 2174
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:370800766"
variation 2248
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:4444493"
variation 2308
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:141123835"
variation 2316
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:187519040"
variation 2345..2360
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="caatcattcctgtcac"
/db_xref="dbSNP:143993746"
variation 2348..2363
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="tcattcctgtcaccaa"
/db_xref="dbSNP:367862174"
variation 2358
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:144723641"
variation 2359
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:151031088"
variation 2360
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:140637703"
variation 2442
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:146942100"
variation 2515
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:199832449"
variation 2547
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:191916595"
variation 2586
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:183240123"
variation 2631
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:137999167"
variation 2660
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:149067484"
variation 2684
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:113527829"
variation 2685
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:148235172"
variation 2787..2788
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="ac"
/db_xref="dbSNP:376210725"
variation 2879
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:141259297"
variation 2964
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:145555745"
polyA_signal 3181..3186
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
polyA_site 3224
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
variation 3262
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:4669522"
variation 3272
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:138161088"
variation 3312
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:142746538"
variation 3329
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:188355532"
variation 3336
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:371202712"
variation 3362
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:367805998"
variation 3429
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:374263399"
variation 3485
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:6722205"
variation 3557
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:7632"
variation 3730
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:146068438"
STS 3750..4006
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/standard_name="A005P43"
/db_xref="UniSTS:22254"
STS 3750..4006
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/standard_name="G20404"
/db_xref="UniSTS:22253"
STS 3760..3871
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/standard_name="RH11597"
/db_xref="UniSTS:10463"
variation 3822
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:192585504"
variation 3848
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:139703378"
variation 3859
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:375562533"
variation 3887
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:14465"
variation 3892
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:14466"
STS 3894..4001
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/standard_name="SHGC-36737"
/db_xref="UniSTS:11113"
variation 3978
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:149368043"
polyA_site 4033
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
ORIGIN
ggggccggggcaacgacgggaggcgggagcgccgcactgccttggaggcggggcaacgcttggaggcgggaacgcggcacgcgagcgttgggggccctaagcgtcgcgacctgggggcttcggggaggtagccgtggacgtgggcagagcgcgggcctcgtggtgtgcgggcactgtgggccgggcgagccccttcccgcccgtgtggttgacatcatggacatatgtgagtccatcctggagaggaagcggcatgacagcgaaaggtctacttgcagcatcttggagcagacagacatggaagctgtcgaggctcttgtttgtatgagctcctggggtcaaagatcccagaaaggtgacctgttgcggataagacccctcacgcctgtctctgactctggggatgtcaccaccactgtgcatatggatgcagccacacctgaactaccaaaagacttccattctttatcgactctgtgcataactcctcctcagagccctgatctcgtggagccatcgacaaggacacctgtttctccccaagtaacagattccaaagcatgtacagccacggatgttctccagtcctctgccgtagtggccagagctctgagcgggggcgcggagaggggcttgctgggtttggagccagtgcccagctctccctgcagggccaaggggactagcgtgatccgacacactggggagagccctgctgcctgctttcccaccatccagactccagattgccggctttctgacagcagagaaggagaagagcagcttctgggacactttgaaactttgcaggacacacacctcacggacagtttactcagcactaacttggtgtcctgtcagccctgcttgcacaagtctggtggcctgctgctcactgacaaaggccagcaggcagggtggcctggtgcagttcagacttgctcaccaaagaattatgaaaatgacctgcccaggaaaaccacccctctgatttctgtctctgtccctgctccccctgtcctttgccagatgatccctgtgactggacaaagtagcatgttaccagcttttttgaagccccctccccagttgtctgtggggactgtgagacccatcctagctcaggctgctccagcgcctcaacctgtgttcgtgggacctgctgtgcctcagggagctgtgatgttggtcctgccccagggagccctccctccgcctgccccctgtgcagccaatgtcatggctgccgggaataccaagttgttgccccttgcccctgctccagtgttcatcacctctagccaaaactgtgtccctcaggtagacttttcccgaaggaggaactatgtttgcagcttcccaggttgccggaagacctacttcaaaagttcccaccttaaggcccatcttcgcactcacacaggggagaagcctttcaactgcagctgggatggctgtgataaaaagtttgctcgttcggatgagctgtcacgccaccgcagaactcacacaggggagaagaagtttgtgtgcccggtgtgtgaccgacgtttcatgcgcagtgaccacctgacgaagcatgcccggcgccacatgacgaccaagaagatcccaggctggcaggcagaggttggcaagctgaacagaatcgcctctgcagagagcccggggagcccactggtgagcatgccagcctctgcctgaaaggtccattaggacatcactcatgggatttttaaaaagcctctttccaggaatggaactgatggattcctctcccactgcctcacccaaaaaaaacggtcttggcggcctaggggaagatcggggagctggttttgatgaaagtatgttaacttttcttttccacttgggaccctgttcagtatcttttgtagtttcagaagtttttttgttttggttttttttttaaagaaatggtagaaaatttgataatctgaatcaccagcattcaaacaaatatttcggcaataaagtttacaaaatctggatttttacaaccttttctattgatgttttgtagaaataagacagggtactaatttttatactggtttttagaaaaatatttatattgttggtgctcaaatcaccaatttctagctagatcattttgcagccttcttttcagtgtttaataacaaagtttttcctaatggcccttcttttagtaaactggacatgttattccactacaaaaaccacaagttatctggccttttagatctttttggaatcggacctggttgagtaaggacctcttaaaagggaaaaataaattttgccgtcagcttcttcataacgttttcaaggaaattctaggcaatcattcctgtcaccaaagaactaaaattttggttgactggaactagtgagctgtgtccatggtgtgtcatgaaggatgtaccccagagagtaacatgagccactgggcagatcccagggaccagtacttgctgcaggatctagtctgtaatagtcttggccatggctctgctgaaagcaagccattcagtttcttgtttgtacctaaaacaccaaaaaagaaacactcaaatccagctgctttgtcaattgtcagttctgactccttttgctgtggccttatccgtactatattgtgggtagagtaacttctcagaaaaaaaggaaatgtctgtattggttggatgaaactccaccagagcacagcttagctggggcgagatgcatgtgaaggcaggcagtgccaagattccgcttcctttgtttgccaaatactagaaacacaaggaaatgcaagttacgctaaatggcagtaatactacccaactgcctttctgttcattttgtttgaaggaaattgttttgaccaaacagaaaattacttggaatggtgtgttttacagtctacctagaaaatagatggacaatatttttcaactgtatgagcacgtagataaccgagagaatgtggccacctgtgttcaagaagccactgatactggtttttgttaaacattggaagttcaggcaatggaataaatgtaggaacatacagaatgttgcactaatttggtagcctgggaattttttttattgtgcagtatgtatttaaattttgtctatgttaattaccagcatttacctttatttaaatgatggtaaggtggaatattgaataaaattaggttttgtgttttgttctttgtagtctgataaaatctccacctggtcattcattgtgtgtgacttgatacctgttaacttgccccttagtatcagctgttacttgacacaaatgtgtgtgttattcagaggttttcagtctggacactccataggtgagtgtcgtgtcttcgtgagacagcacagttgtctcatgttgtgcatagttcatgtttcctcaccacccagtcctttctcctgctcatcaaaatcagcatacacatttttgactgtacacactataaatggcatcaaatttggatatttttcttaattatgacatgcaaagtaatgtgagtcctgccagtattctggtggataaggtcttttgagtatttggttgcttgtcacaacattctccaagcagtgatatttctaaagaggagatacatgttgaaaacggttttaatttacacttccatttcctgattacatttggaaatactttgtgtaaaccatcccccttccacctccatttgtctgttgaaagattttaagttggaaacagttcctgtctgaaaactcttctgagaaccacaaaccttgtgtatggattcggcatggagccctcagctggcggctctgggtgctgacggccgctggagaggtgggctcccctcgtgcactttattgcctgggcagttttgcttgatcttttgtgactttgagccttttaagtagtttgaatgataagacttaaaatgtttcataattatgttttatgtaacagactttgacattatttaaacgagcatgtgtaatgtaacttttctctttgaatcatataaaacttgattttacattgaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:8462 -> Molecular function: GO:0000981 [sequence-specific DNA binding RNA polymerase II transcription factor activity] evidence: IDA
GeneID:8462 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: TAS
GeneID:8462 -> Molecular function: GO:0044212 [transcription regulatory region DNA binding] evidence: IDA
GeneID:8462 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA
GeneID:8462 -> Biological process: GO:0000115 [regulation of transcription involved in S phase of mitotic cell cycle] evidence: IDA
GeneID:8462 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:8462 -> Biological process: GO:0006366 [transcription from RNA polymerase II promoter] evidence: TAS
GeneID:8462 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:8462 -> Biological process: GO:0008285 [negative regulation of cell proliferation] evidence: IDA
GeneID:8462 -> Biological process: GO:0043065 [positive regulation of apoptotic process] evidence: IDA
GeneID:8462 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
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