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2024-04-26 00:24:33, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001177716 3906 bp mRNA linear PRI 14-APR-2013
DEFINITION Homo sapiens Kruppel-like factor 11 (KLF11), transcript variant 2,
mRNA.
ACCESSION NM_001177716
VERSION NM_001177716.1 GI:295148160
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3906)
AUTHORS Fan,Y., Guo,Y., Zhang,J., Subramaniam,M., Song,C.Z., Urrutia,R. and
Chen,Y.E.
TITLE Kruppel-like factor-11, a transcription factor involved in diabetes
mellitus, suppresses endothelial cell activation via the nuclear
factor-kappaB signaling pathway
JOURNAL Arterioscler. Thromb. Vasc. Biol. 32 (12), 2981-2988 (2012)
PUBMED 23042817
REMARK GeneRIF: Kruppel-like factor-11, a transcription factor involved in
diabetes mellitus, suppresses endothelial cell activation via the
nuclear factor-kappaB signaling pathway.
REFERENCE 2 (bases 1 to 3906)
AUTHORS Faryna,M., Konermann,C., Aulmann,S., Bermejo,J.L., Brugger,M.,
Diederichs,S., Rom,J., Weichenhan,D., Claus,R., Rehli,M.,
Schirmacher,P., Sinn,H.P., Plass,C. and Gerhauser,C.
TITLE Genome-wide methylation screen in low-grade breast cancer
identifies novel epigenetically altered genes as potential
biomarkers for tumor diagnosis
JOURNAL FASEB J. 26 (12), 4937-4950 (2012)
PUBMED 22930747
REMARK GeneRIF: Data indicate that median methylation levels of BCAN,
HOXD1, KCTD8, KLF11, NXPH1, POU4F1, SIM1, and TCF7L1 were >/=30%
higher than in normal samples, representing potential biomarkers
for tumor diagnosis.
REFERENCE 3 (bases 1 to 3906)
AUTHORS Perakakis,N., Danassi,D., Alt,M., Tsaroucha,E., Mehana,A.E.,
Rimmer,N., Laubner,K., Wang,H., Wollheim,C.B., Seufert,J. and
Path,G.
TITLE Human Kruppel-like factor 11 differentially regulates human insulin
promoter activity in beta-cells and non-beta-cells via p300 and
PDX1 through the regulatory sites A3 and CACCC box
JOURNAL Mol. Cell. Endocrinol. 363 (1-2), 20-26 (2012)
PUBMED 22801105
REMARK GeneRIF: KLF11 has a role in fine-tuning insulin transcription in
certain cellular situations rather than representing a major
transcriptional activator or repressor of the insulin gene.
REFERENCE 4 (bases 1 to 3906)
AUTHORS Grunewald,M., Johnson,S., Lu,D., Wang,Z., Lomberk,G., Albert,P.R.,
Stockmeier,C.A., Meyer,J.H., Urrutia,R., Miczek,K.A., Austin,M.C.,
Wang,J., Paul,I.A., Woolverton,W.L., Seo,S., Sittman,D.B. and
Ou,X.M.
TITLE Mechanistic role for a novel glucocorticoid-KLF11 (TIEG2) protein
pathway in stress-induced monoamine oxidase A expression
JOURNAL J. Biol. Chem. 287 (29), 24195-24206 (2012)
PUBMED 22628545
REMARK GeneRIF: KLF11 is an MAO A regulator and is produced in response to
neuronal stress, which transcriptionally activates MAO A.
REFERENCE 5 (bases 1 to 3906)
AUTHORS Seo,S., Lomberk,G., Mathison,A., Buttar,N., Podratz,J., Calvo,E.,
Iovanna,J., Brimijoin,S., Windebank,A. and Urrutia,R.
TITLE Kruppel-like factor 11 differentially couples to histone
acetyltransferase and histone methyltransferase chromatin
remodeling pathways to transcriptionally regulate dopamine D2
receptor in neuronal cells
JOURNAL J. Biol. Chem. 287 (16), 12723-12735 (2012)
PUBMED 22375010
REMARK GeneRIF: Here we report the characterization of two antagonistic,
chromatin-mediated mechanisms by which KLF11 regulated the
transcription of the dopamine D2 receptor.
REFERENCE 6 (bases 1 to 3906)
AUTHORS Jia,L., Young,M.F., Powell,J., Yang,L., Ho,N.C., Hotchkiss,R.,
Robey,P.G. and Francomano,C.A.
TITLE Gene expression profile of human bone marrow stromal cells:
high-throughput expressed sequence tag sequencing analysis
JOURNAL Genomics 79 (1), 7-17 (2002)
PUBMED 11827452
REFERENCE 7 (bases 1 to 3906)
AUTHORS Zhang,J.S., Moncrieffe,M.C., Kaczynski,J., Ellenrieder,V.,
Prendergast,F.G. and Urrutia,R.
TITLE A conserved alpha-helical motif mediates the interaction of
Sp1-like transcriptional repressors with the corepressor mSin3A
JOURNAL Mol. Cell. Biol. 21 (15), 5041-5049 (2001)
PUBMED 11438660
REFERENCE 8 (bases 1 to 3906)
AUTHORS Scohy,S., Gabant,P., Van Reeth,T., Hertveldt,V., Dreze,P.L., Van
Vooren,P., Riviere,M., Szpirer,J. and Szpirer,C.
TITLE Identification of KLF13 and KLF14 (SP6), novel members of the
SP/XKLF transcription factor family
JOURNAL Genomics 70 (1), 93-101 (2000)
PUBMED 11087666
REFERENCE 9 (bases 1 to 3906)
AUTHORS Asano,H., Li,X.S. and Stamatoyannopoulos,G.
TITLE FKLF, a novel Kruppel-like factor that activates human embryonic
and fetal beta-like globin genes
JOURNAL Mol. Cell. Biol. 19 (5), 3571-3579 (1999)
PUBMED 10207080
REFERENCE 10 (bases 1 to 3906)
AUTHORS Cook,T., Gebelein,B., Mesa,K., Mladek,A. and Urrutia,R.
TITLE Molecular cloning and characterization of TIEG2 reveals a new
subfamily of transforming growth factor-beta-inducible Sp1-like
zinc finger-encoding genes involved in the regulation of cell
growth
JOURNAL J. Biol. Chem. 273 (40), 25929-25936 (1998)
PUBMED 9748269
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AK316439.1, AC104794.4,
BC063286.1 and AI755210.1.
Summary: The protein encoded by this gene is a zinc finger
transcription factor that binds to SP1-like sequences in epsilon-
and gamma-globin gene promoters. This binding inhibits cell growth
and causes apoptosis. Defects in this gene are a cause of
maturity-onset diabetes of the young type 7 (MODY7). Three
transcript variants encoding two different isoforms have been found
for this gene. [provided by RefSeq, Apr 2010].
Transcript Variant: This variant (2) differs in the 5' UTR and
coding sequence compared to variant 1. The resulting isoform (b) is
shorter at the N-terminus compared to isoform a. Variants 2 and 3
both encode the same isoform (b).
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AK316439.1 [ECO:0000332]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-14 AK316439.1 1-14
15-15 AC104794.4 25793-25793
16-201 AK316439.1 16-201
202-202 AC104794.4 28242-28242
203-1782 AK316439.1 203-1782
1783-3409 AC104794.4 34684-36310
3410-3685 BC063286.1 3556-3831
3686-3906 AI755210.1 1-221 c
FEATURES Location/Qualifiers
source 1..3906
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p25"
gene 1..3906
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="Kruppel-like factor 11"
/db_xref="GeneID:8462"
/db_xref="HGNC:11811"
/db_xref="MIM:603301"
exon 1..59
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/inference="alignment:Splign:1.39.8"
variation 15
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:115226520"
exon 60..329
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/inference="alignment:Splign:1.39.8"
variation 66
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200094318"
CDS 69..1556
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="isoform b is encoded by transcript variant 2;
krueppel-like factor 11; TIEG-2; TGFB-inducible early
growth response protein 2; transforming growth
factor-beta-inducible early growth response protein 2"
/codon_start=1
/product="Krueppel-like factor 11 isoform b"
/protein_id="NP_001171187.1"
/db_xref="GI:295148161"
/db_xref="CCDS:CCDS54333.1"
/db_xref="GeneID:8462"
/db_xref="HGNC:11811"
/db_xref="MIM:603301"
/translation="
MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQRSQKGDLLRIRPLTPVSDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTATDVLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTGESPAACFPTIQTPDCRLSDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGWPGAVQTCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLPAFLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAGNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIASAESPGSPLVSMPASA
"
misc_feature 1194..>1364
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="FOG: Zn-finger [General function prediction only];
Region: COG5048"
/db_xref="CDD:34653"
misc_feature 1245..1328
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="Zinc-finger double domain; Region: zf-H2C2_2;
pfam13465"
/db_xref="CDD:205643"
misc_feature 1335..1406
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="Zinc-finger double domain; Region: zf-H2C2_2;
pfam13465"
/db_xref="CDD:205643"
misc_feature 1380..1445
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/note="Zinc finger, C2H2 type; Region: zf-C2H2; cl15478"
/db_xref="CDD:210117"
variation 69
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:373697732"
variation 85
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:367566983"
variation 98
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:140643007"
variation 103
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:150096859"
variation 107
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:146577005"
variation 110
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:371327904"
variation 158
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:138710480"
STS 173..305
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/standard_name="RH78629"
/db_xref="UniSTS:80550"
variation 194
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:201555141"
variation 202
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:35927125"
variation 219
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:202142040"
variation 236
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:373935239"
variation 242
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:144083374"
variation 258
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200260496"
variation 261
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:76059450"
variation 292
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:146264648"
exon 330..1275
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/inference="alignment:Splign:1.39.8"
variation 330
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="t"
/db_xref="dbSNP:55653873"
variation 375
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:201792575"
variation 388
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:61755332"
variation 395
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:199941261"
variation 424
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:139111425"
variation 427
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:145933214"
variation 446
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:113903638"
variation 454
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:148968483"
variation 464
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:368067336"
variation 468
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:147735654"
variation 473
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:373126146"
variation 503
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:146462049"
variation 518
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:377399356"
variation 539
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:200997824"
variation 547
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:140504133"
variation 549
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:138601862"
variation 558
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:146238335"
variation 560
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:142659789"
variation 563
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:142266428"
variation 594
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:368982748"
variation 614
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:150737124"
variation 625
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:145588324"
variation 660
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:374436407"
variation complement(676)
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:34336420"
variation 688
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:148922317"
variation 690
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:200061013"
variation 696
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200561467"
variation 706
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:370039403"
variation 714
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:373828519"
variation 719
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:372266786"
variation 774
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:374251576"
variation 779
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:372404632"
variation 799
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:148123124"
variation 823
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:145504876"
variation 828
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:368207952"
variation 838
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:142673414"
variation 868
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:372404152"
variation 887
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:149235463"
variation 893
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:201595721"
variation 927
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:200635526"
variation 937
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:182304641"
variation 969
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:377198797"
variation 970
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:144431930"
variation 972
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:368577352"
variation 989
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:143517559"
variation 991
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:144949098"
variation 1004
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:371589306"
variation 1009
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:151317435"
variation 1011
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:375265808"
variation 1019
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:369681560"
variation 1041
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:373173330"
variation 1056
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:121912645"
variation 1065
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:199649394"
variation 1067
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:145193520"
variation 1075
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:141318309"
variation 1094
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:146486664"
variation 1100
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:371102481"
variation 1113
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:372514890"
variation 1119
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:144897109"
variation 1135
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:141324729"
variation 1137
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:201432055"
variation 1147
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:370236540"
variation 1148
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:137865082"
variation 1150
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:35476458"
variation 1154
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:199624763"
variation 1178
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:117449189"
variation 1202
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:11687357"
variation 1217
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:201561310"
variation 1222
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:34762805"
variation 1263
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:369331650"
exon 1276..3885
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/inference="alignment:Splign:1.39.8"
variation 1327
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:369814305"
variation 1379
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:373796305"
variation 1399
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:199770737"
variation 1410
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:200532025"
variation 1411
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:142970758"
variation 1415
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:374953405"
variation 1446
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:151292984"
variation 1450
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:369974149"
variation 1465
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:201735305"
variation 1519
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:377358836"
variation 1520
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:36091043"
variation 1599
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:75910133"
variation 1603
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:370864119"
variation 1663
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:140559044"
variation 1750
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:76220150"
variation 1772
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:199892235"
variation 1773..1774
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="t"
/replace="tt"
/db_xref="dbSNP:34206941"
variation 1773
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:201145049"
variation 1774
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:112893539"
variation 1784
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:78254957"
variation 1791
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:150051327"
variation 1797
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:191010106"
variation 1811
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:111703851"
variation 1818
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:147746428"
variation 1967
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:183232432"
variation 1991
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:72786612"
variation 2026
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:370800766"
variation 2100
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:4444493"
variation 2160
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:141123835"
variation 2168
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:187519040"
variation 2197..2212
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="caatcattcctgtcac"
/db_xref="dbSNP:143993746"
variation 2200..2215
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="tcattcctgtcaccaa"
/db_xref="dbSNP:367862174"
variation 2210
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:144723641"
variation 2211
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:151031088"
variation 2212
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:140637703"
variation 2294
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:146942100"
variation 2367
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:199832449"
variation 2399
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:191916595"
variation 2438
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:183240123"
variation 2483
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:137999167"
variation 2512
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:149067484"
variation 2536
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:113527829"
variation 2537
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:148235172"
variation 2639..2640
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace=""
/replace="ac"
/db_xref="dbSNP:376210725"
variation 2731
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="t"
/db_xref="dbSNP:141259297"
variation 2816
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:145555745"
polyA_signal 3033..3038
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
polyA_site 3076
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
variation 3114
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:4669522"
variation 3124
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:138161088"
variation 3164
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="g"
/replace="t"
/db_xref="dbSNP:142746538"
variation 3181
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:188355532"
variation 3188
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:371202712"
variation 3214
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:367805998"
variation 3281
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:374263399"
variation 3337
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:6722205"
variation 3409
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:7632"
variation 3582
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="g"
/db_xref="dbSNP:146068438"
STS 3602..3858
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/standard_name="A005P43"
/db_xref="UniSTS:22254"
STS 3602..3858
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/standard_name="G20404"
/db_xref="UniSTS:22253"
STS 3612..3723
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/standard_name="RH11597"
/db_xref="UniSTS:10463"
variation 3674
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:192585504"
variation 3700
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:139703378"
variation 3711
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="c"
/replace="t"
/db_xref="dbSNP:375562533"
variation 3739
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="c"
/db_xref="dbSNP:14465"
variation 3744
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:14466"
STS 3746..3853
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/standard_name="SHGC-36737"
/db_xref="UniSTS:11113"
variation 3830
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
/replace="a"
/replace="g"
/db_xref="dbSNP:149368043"
polyA_site 3885
/gene="KLF11"
/gene_synonym="FKLF; FKLF1; MODY7; TIEG2; Tieg3"
ORIGIN
actcgcgcgcctgtaaatgcgggaggtggggcgtgcagggcttcgctgcggccgcgccggttgacatcatggacatatgtgagtccatcctggagaggaagcggcatgacagcgaaaggtctacttgcagcatcttggagcagacagacatggaagctgtcgaggctcttgtttgtatgagctcctggggtcaaagatcccagaaaggtgacctgttgcggataagacccctcacgcctgtctctgactctggggatgtcaccaccactgtgcatatggatgcagccacacctgaactaccaaaagacttccattctttatcgactctgtgcataactcctcctcagagccctgatctcgtggagccatcgacaaggacacctgtttctccccaagtaacagattccaaagcatgtacagccacggatgttctccagtcctctgccgtagtggccagagctctgagcgggggcgcggagaggggcttgctgggtttggagccagtgcccagctctccctgcagggccaaggggactagcgtgatccgacacactggggagagccctgctgcctgctttcccaccatccagactccagattgccggctttctgacagcagagaaggagaagagcagcttctgggacactttgaaactttgcaggacacacacctcacggacagtttactcagcactaacttggtgtcctgtcagccctgcttgcacaagtctggtggcctgctgctcactgacaaaggccagcaggcagggtggcctggtgcagttcagacttgctcaccaaagaattatgaaaatgacctgcccaggaaaaccacccctctgatttctgtctctgtccctgctccccctgtcctttgccagatgatccctgtgactggacaaagtagcatgttaccagcttttttgaagccccctccccagttgtctgtggggactgtgagacccatcctagctcaggctgctccagcgcctcaacctgtgttcgtgggacctgctgtgcctcagggagctgtgatgttggtcctgccccagggagccctccctccgcctgccccctgtgcagccaatgtcatggctgccgggaataccaagttgttgccccttgcccctgctccagtgttcatcacctctagccaaaactgtgtccctcaggtagacttttcccgaaggaggaactatgtttgcagcttcccaggttgccggaagacctacttcaaaagttcccaccttaaggcccatcttcgcactcacacaggggagaagcctttcaactgcagctgggatggctgtgataaaaagtttgctcgttcggatgagctgtcacgccaccgcagaactcacacaggggagaagaagtttgtgtgcccggtgtgtgaccgacgtttcatgcgcagtgaccacctgacgaagcatgcccggcgccacatgacgaccaagaagatcccaggctggcaggcagaggttggcaagctgaacagaatcgcctctgcagagagcccggggagcccactggtgagcatgccagcctctgcctgaaaggtccattaggacatcactcatgggatttttaaaaagcctctttccaggaatggaactgatggattcctctcccactgcctcacccaaaaaaaacggtcttggcggcctaggggaagatcggggagctggttttgatgaaagtatgttaacttttcttttccacttgggaccctgttcagtatcttttgtagtttcagaagtttttttgttttggttttttttttaaagaaatggtagaaaatttgataatctgaatcaccagcattcaaacaaatatttcggcaataaagtttacaaaatctggatttttacaaccttttctattgatgttttgtagaaataagacagggtactaatttttatactggtttttagaaaaatatttatattgttggtgctcaaatcaccaatttctagctagatcattttgcagccttcttttcagtgtttaataacaaagtttttcctaatggcccttcttttagtaaactggacatgttattccactacaaaaaccacaagttatctggccttttagatctttttggaatcggacctggttgagtaaggacctcttaaaagggaaaaataaattttgccgtcagcttcttcataacgttttcaaggaaattctaggcaatcattcctgtcaccaaagaactaaaattttggttgactggaactagtgagctgtgtccatggtgtgtcatgaaggatgtaccccagagagtaacatgagccactgggcagatcccagggaccagtacttgctgcaggatctagtctgtaatagtcttggccatggctctgctgaaagcaagccattcagtttcttgtttgtacctaaaacaccaaaaaagaaacactcaaatccagctgctttgtcaattgtcagttctgactccttttgctgtggccttatccgtactatattgtgggtagagtaacttctcagaaaaaaaggaaatgtctgtattggttggatgaaactccaccagagcacagcttagctggggcgagatgcatgtgaaggcaggcagtgccaagattccgcttcctttgtttgccaaatactagaaacacaaggaaatgcaagttacgctaaatggcagtaatactacccaactgcctttctgttcattttgtttgaaggaaattgttttgaccaaacagaaaattacttggaatggtgtgttttacagtctacctagaaaatagatggacaatatttttcaactgtatgagcacgtagataaccgagagaatgtggccacctgtgttcaagaagccactgatactggtttttgttaaacattggaagttcaggcaatggaataaatgtaggaacatacagaatgttgcactaatttggtagcctgggaattttttttattgtgcagtatgtatttaaattttgtctatgttaattaccagcatttacctttatttaaatgatggtaaggtggaatattgaataaaattaggttttgtgttttgttctttgtagtctgataaaatctccacctggtcattcattgtgtgtgacttgatacctgttaacttgccccttagtatcagctgttacttgacacaaatgtgtgtgttattcagaggttttcagtctggacactccataggtgagtgtcgtgtcttcgtgagacagcacagttgtctcatgttgtgcatagttcatgtttcctcaccacccagtcctttctcctgctcatcaaaatcagcatacacatttttgactgtacacactataaatggcatcaaatttggatatttttcttaattatgacatgcaaagtaatgtgagtcctgccagtattctggtggataaggtcttttgagtatttggttgcttgtcacaacattctccaagcagtgatatttctaaagaggagatacatgttgaaaacggttttaatttacacttccatttcctgattacatttggaaatactttgtgtaaaccatcccccttccacctccatttgtctgttgaaagattttaagttggaaacagttcctgtctgaaaactcttctgagaaccacaaaccttgtgtatggattcggcatggagccctcagctggcggctctgggtgctgacggccgctggagaggtgggctcccctcgtgcactttattgcctgggcagttttgcttgatcttttgtgactttgagccttttaagtagtttgaatgataagacttaaaatgtttcataattatgttttatgtaacagactttgacattatttaaacgagcatgtgtaatgtaacttttctctttgaatcatataaaacttgattttacattgaaaaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:8462 -> Molecular function: GO:0000981 [sequence-specific DNA binding RNA polymerase II transcription factor activity] evidence: IDA
GeneID:8462 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: TAS
GeneID:8462 -> Molecular function: GO:0044212 [transcription regulatory region DNA binding] evidence: IDA
GeneID:8462 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA
GeneID:8462 -> Biological process: GO:0000115 [regulation of transcription involved in S phase of mitotic cell cycle] evidence: IDA
GeneID:8462 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:8462 -> Biological process: GO:0006366 [transcription from RNA polymerase II promoter] evidence: TAS
GeneID:8462 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:8462 -> Biological process: GO:0008285 [negative regulation of cell proliferation] evidence: IDA
GeneID:8462 -> Biological process: GO:0043065 [positive regulation of apoptotic process] evidence: IDA
GeneID:8462 -> Cellular component: GO:0005634 [nucleus] evidence: IEA
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