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2024-04-26 03:49:56, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001174168 4927 bp mRNA linear PRI 15-JUL-2013
DEFINITION Homo sapiens spleen tyrosine kinase (SYK), transcript variant 4,
mRNA.
ACCESSION NM_001174168 NR_024156
VERSION NM_001174168.1 GI:293332610
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4927)
AUTHORS Yu,S., Huang,H., Iliuk,A., Wang,W.H., Jayasundera,K.B., Tao,W.A.,
Post,C.B. and Geahlen,R.L.
TITLE Syk inhibits the activity of protein kinase A by phosphorylating
tyrosine 330 of the catalytic subunit
JOURNAL J. Biol. Chem. 288 (15), 10870-10881 (2013)
PUBMED 23447535
REMARK GeneRIF: PKA is a novel substrate of Syk, and its phosphorylation
on Tyr-330 inhibits its participation in downstream signaling
pathways.
REFERENCE 2 (bases 1 to 4927)
AUTHORS Kim,Y., Kong,M. and Lee,C.
TITLE Association of intronic sequence variant in the gene encoding
spleen tyrosine kinase with susceptibility to vascular dementia
JOURNAL World J. Biol. Psychiatry 14 (3), 220-226 (2013)
PUBMED 23480133
REFERENCE 3 (bases 1 to 4927)
AUTHORS Vallieres,F. and Girard,D.
TITLE IL-21 enhances phagocytosis in mononuclear phagocyte cells:
identification of spleen tyrosine kinase as a novel molecular
target of IL-21
JOURNAL J. Immunol. 190 (6), 2904-2912 (2013)
PUBMED 23396946
REMARK GeneRIF: Spleen tyrosine kinase (Syk) is a novel and important
target of interleukin (IL)-21 for enhancing phagocytosis.
REFERENCE 4 (bases 1 to 4927)
AUTHORS Hussain,A., Mohammad,D.K., Gustafsson,M.O., Uslu,M., Hamasy,A.,
Nore,B.F., Mohamed,A.J. and Smith,C.I.
TITLE Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK
(spleen tyrosine kinase) fusion kinase is dependent on adapter
SLP-76 and on the adapter function of the kinases SYK and ZAP70
JOURNAL J. Biol. Chem. 288 (10), 7338-7350 (2013)
PUBMED 23293025
REMARK GeneRIF: Data indicate that the intracellular signaling of ITK-SYK
requires both SLP-76 and the adapter function of SYK/ZAP-70
kinases.
REFERENCE 5 (bases 1 to 4927)
AUTHORS Romero-Camarero,I., Jiang,X., Natkunam,Y., Lu,X.,
Vicente-Duenas,C., Gonzalez-Herrero,I., Flores,T., Garcia,J.L.,
McNamara,G., Kunder,C., Zhao,S., Segura,V., Fontan,L.,
Martinez-Climent,J.A., Garcia-Criado,F.J., Theis,J.D., Dogan,A.,
Campos-Sanchez,E., Green,M.R., Alizadeh,A.A., Cobaleda,C.,
Sanchez-Garcia,I. and Lossos,I.S.
TITLE Germinal centre protein HGAL promotes lymphoid hyperplasia and
amyloidosis via BCR-mediated Syk activation
JOURNAL Nat Commun 4, 1338 (2013)
PUBMED 23299888
REMARK GeneRIF: the germinal centre protein human germinal
centre-associated lymphoma regulates B-cell receptor signalling in
B-lymphocytes which, without appropriate control, may lead to
B-cell lymphoproliferation.
REFERENCE 6 (bases 1 to 4927)
AUTHORS Chan,A.C., Iwashima,M., Turck,C.W. and Weiss,A.
TITLE ZAP-70: a 70 kd protein-tyrosine kinase that associates with the
TCR zeta chain
JOURNAL Cell 71 (4), 649-662 (1992)
PUBMED 1423621
REFERENCE 7 (bases 1 to 4927)
AUTHORS Hutchcroft,J.E., Harrison,M.L. and Geahlen,R.L.
TITLE Association of the 72-kDa protein-tyrosine kinase PTK72 with the B
cell antigen receptor
JOURNAL J. Biol. Chem. 267 (12), 8613-8619 (1992)
PUBMED 1569106
REFERENCE 8 (bases 1 to 4927)
AUTHORS Yannoukakos,D., Meyer,H.E., Vasseur,C., Driancourt,C., Wajcman,H.
and Bursaux,E.
TITLE Three regions of erythrocyte band 3 protein are phosphorylated on
tyrosines: characterization of the phosphorylation sites by solid
phase sequencing combined with capillary electrophoresis
JOURNAL Biochim. Biophys. Acta 1066 (1), 70-76 (1991)
PUBMED 2065070
REFERENCE 9 (bases 1 to 4927)
AUTHORS Yannoukakos,D., Vasseur,C., Piau,J.P., Wajcman,H. and Bursaux,E.
TITLE Phosphorylation sites in human erythrocyte band 3 protein
JOURNAL Biochim. Biophys. Acta 1061 (2), 253-266 (1991)
PUBMED 1998697
REFERENCE 10 (bases 1 to 4927)
AUTHORS Kim,J.W., Sim,S.S., Kim,U.H., Nishibe,S., Wahl,M.I., Carpenter,G.
and Rhee,S.G.
TITLE Tyrosine residues in bovine phospholipase C-gamma phosphorylated by
the epidermal growth factor receptor in vitro
JOURNAL J. Biol. Chem. 265 (7), 3940-3943 (1990)
PUBMED 1689310
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA587403.1, BC011399.1,
BC001645.2, AL354862.12 and W33104.1.
On Apr 3, 2010 this sequence version replaced gi:205277438.
Summary: This gene encodes a member of the family of non-receptor
type Tyr protein kinases. This protein is widely expressed in
hematopoietic cells and is involved in coupling activated
immunoreceptors to downstream signaling events that mediate diverse
cellular responses, including proliferation, differentiation, and
phagocytosis. It is thought to be a modulator of epithelial cell
growth and a potential tumour suppressor in human breast
carcinomas. Alternatively spliced transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq, Mar 2010].
Transcript Variant: This variant (4) contains an alternate 5'
terminal exon and lacks an in-frame coding exon compared to variant
1. The former introduces an upstream open reading frame (uORF) with
a weak Kozak signal, making translation of the downstream primary
ORF (with a strong Kozak signal) encoding isoform 2 likely by leaky
scanning or re-initiation. Variants 2 and 4 encode the same
isoform.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BC011399.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025091 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-18 DA587403.1 1-18
19-2284 BC011399.1 1-2266
2285-2563 BC001645.2 2379-2657
2564-4785 AL354862.12 145283-147504
4786-4927 W33104.1 1-142 c
FEATURES Location/Qualifiers
source 1..4927
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="9q22"
gene 1..4927
/gene="SYK"
/gene_synonym="p72-Syk"
/note="spleen tyrosine kinase"
/db_xref="GeneID:6850"
/db_xref="HGNC:11491"
/db_xref="MIM:600085"
exon 1..81
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 3
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:201070811"
variation 8
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:202157876"
variation 39
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200151250"
variation 69
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:201346230"
variation 71
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201810658"
variation 75
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200253631"
variation 80
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200807147"
exon 82..539
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 94
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200237145"
variation 102
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201338526"
variation 110
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201341126"
variation 111
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200373424"
misc_feature 117..119
/gene="SYK"
/gene_synonym="p72-Syk"
/note="upstream in-frame stop codon"
CDS 123..1961
/gene="SYK"
/gene_synonym="p72-Syk"
/EC_number="2.7.10.2"
/note="isoform 2 is encoded by transcript variant 4;
tyrosine-protein kinase SYK"
/codon_start=1
/product="tyrosine-protein kinase SYK isoform 2"
/protein_id="NP_001167639.1"
/db_xref="GI:293332611"
/db_xref="CCDS:CCDS47992.1"
/db_xref="GeneID:6850"
/db_xref="HGNC:11491"
/db_xref="MIM:600085"
/translation="
MASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPFEDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPASSPAQGNRQESTVSFNPYEPELAPWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
"
misc_feature 159..470
/gene="SYK"
/gene_synonym="p72-Syk"
/note="N-terminal Src homology 2 (SH2) domain found in
Zeta-chain-associated protein kinase 70 (ZAP-70) and
Spleen tyrosine kinase (Syk) proteins; Region:
SH2_N-SH2_Zap70_Syk_like; cd09938"
/db_xref="CDD:198191"
misc_feature order(186..188,246..248,309..311,315..317)
/gene="SYK"
/gene_synonym="p72-Syk"
/note="phosphotyrosine binding pocket [polypeptide
binding]; other site"
/db_xref="CDD:198191"
misc_feature order(312..314,348..353,357..359,414..419)
/gene="SYK"
/gene_synonym="p72-Syk"
/note="hydrophobic binding pocket [polypeptide binding];
other site"
/db_xref="CDD:198191"
misc_feature 612..908
/gene="SYK"
/gene_synonym="p72-Syk"
/note="C-terminal Src homology 2 (SH2) domain found in
Spleen tyrosine kinase (Syk) proteins; Region:
SH2_C-SH2_Syk_like; cd10401"
/db_xref="CDD:198264"
misc_feature order(645..647,705..707,711..713,765..767,771..773)
/gene="SYK"
/gene_synonym="p72-Syk"
/note="phosphotyrosine binding pocket [polypeptide
binding]; other site"
/db_xref="CDD:198264"
misc_feature order(768..770,804..806,813..815,870..872)
/gene="SYK"
/gene_synonym="p72-Syk"
/note="hydrophobic binding pocket [polypeptide binding];
other site"
/db_xref="CDD:198264"
misc_feature 1173..1931
/gene="SYK"
/gene_synonym="p72-Syk"
/note="Protein tyrosine kinase; Region: Pkinase_Tyr;
pfam07714"
/db_xref="CDD:203736"
misc_feature 1176..1946
/gene="SYK"
/gene_synonym="p72-Syk"
/note="Catalytic domain of the Protein Tyrosine Kinase,
Spleen tyrosine kinase; Region: PTKc_Syk; cd05116"
/db_xref="CDD:133247"
misc_feature order(1182..1196,1206..1208,1251..1253,1257..1259,
1350..1352,1395..1406,1413..1418,1533..1535,1545..1550,
1554..1556,1587..1589,1644..1658,1683..1685,1785..1787)
/gene="SYK"
/gene_synonym="p72-Syk"
/note="active site"
/db_xref="CDD:133247"
misc_feature order(1182..1187,1206..1208,1251..1253,1257..1259,
1350..1352,1395..1406,1413..1418,1545..1550,1554..1556,
1584..1589)
/gene="SYK"
/gene_synonym="p72-Syk"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:133247"
misc_feature order(1533..1535,1545..1547,1644..1658,1683..1685,
1785..1787)
/gene="SYK"
/gene_synonym="p72-Syk"
/note="substrate binding site [chemical binding]; other
site"
/db_xref="CDD:133247"
misc_feature 1584..1664
/gene="SYK"
/gene_synonym="p72-Syk"
/note="activation loop (A-loop); other site"
/db_xref="CDD:133247"
variation 126
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201301123"
variation 134
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199823436"
variation 135
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:146743944"
variation 139
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201350143"
variation 149
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201458538"
variation 150
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:199606629"
variation 173
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200626943"
variation 187
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:140421546"
variation 188
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:139401525"
variation 203
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200577589"
variation 219
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201364101"
STS 223..447
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="STS-S80267"
/db_xref="UniSTS:70625"
variation 251
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:35758162"
variation 256
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:16906862"
variation 257
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201774526"
variation 269
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:140490837"
variation 275
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200928765"
variation 284
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:150440676"
variation 285
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200078199"
variation 293
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:371908826"
variation 314
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:138271353"
variation 316
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:149603234"
variation 334
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:146786995"
variation 337
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200175081"
variation 344
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:139316651"
variation 350
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202064642"
variation 353
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200362424"
variation 364
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201374653"
variation 373
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199818587"
variation 378
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201455170"
variation 381
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201177148"
variation 385
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:78791900"
variation 392
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199646361"
variation 412
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:200223184"
variation 433
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200453337"
variation 450
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202043759"
variation 451
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:375028044"
variation 458
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:143342183"
variation 532
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200097669"
variation 536
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:142980255"
exon 540..700
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 551
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199932327"
variation 554
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:370551918"
variation 561
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:373730562"
variation 596
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200921683"
variation 629
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:147347882"
variation 666
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200476529"
variation 692
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:148413110"
variation 695
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201529865"
exon 701..839
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 749
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202000893"
variation 767
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201867954"
variation 809
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199938327"
variation 810
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200498885"
variation 829
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201857010"
variation 830
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:200087795"
exon 840..918
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 854
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201907766"
variation 859
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:184127752"
variation 881
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:34489331"
variation 897
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:201538038"
variation 906
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:112619650"
variation 909
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199886319"
exon 919..968
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 938
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201662709"
variation 940
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:139520862"
variation 941
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:55920107"
variation 944
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200859639"
variation 966
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:377620701"
variation 967
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201994789"
variation 968
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199908671"
exon 969..1056
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 974
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:146732805"
variation 985
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199612745"
variation 990
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200684262"
variation 991
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201840933"
variation 992
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:199745532"
variation 1019
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200697355"
variation 1039
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201358181"
exon 1057..1234
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 1057
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:139388374"
variation 1060
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200099811"
variation 1062
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:144168552"
variation 1066
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:56071116"
variation 1072
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200994798"
variation 1074
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200409467"
variation 1097
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:142936514"
variation 1109
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:41274652"
variation 1110
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200167353"
variation 1111
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:201479078"
variation 1112
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:377587992"
variation 1118
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:2290890"
variation 1128
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200418715"
variation 1134
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201460357"
variation 1153
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199772052"
variation 1160
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:376461830"
variation 1165
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:369986984"
variation 1166
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:151053124"
variation 1176
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201179887"
variation 1196
/gene="SYK"
/gene_synonym="p72-Syk"
/replace=""
/replace="t"
/db_xref="dbSNP:67128367"
exon 1235..1444
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 1247
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:375613854"
variation 1257
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:79190821"
variation 1271
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202093746"
STS 1286..1542
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="SYK-1"
/db_xref="UniSTS:513716"
variation 1287
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:201438493"
variation 1322
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200930117"
variation 1346
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:141000507"
variation 1349
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202166418"
variation 1355
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:2290888"
variation 1361
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201416422"
variation 1370
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202191431"
variation 1371
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200202947"
variation 1391
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:2290887"
variation 1409
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199712945"
variation 1418
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:143304676"
exon 1445..1634
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 1462
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201930376"
variation 1478
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200072255"
variation 1484
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:56285406"
variation 1485
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201724218"
variation 1497
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200456955"
variation 1501
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:147125933"
variation 1538
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200991736"
variation 1550
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:2306042"
variation 1574
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:2306041"
variation 1580
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201341572"
variation 1583
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202069669"
variation 1586
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200251333"
variation 1592
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:34231418"
variation 1598
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:2306040"
variation 1611
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200320837"
exon 1635..1775
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 1646
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200628553"
variation 1663
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:371627100"
variation 1670
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201650753"
variation 1676
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201516360"
variation 1691
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:201065688"
variation 1708
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199801793"
variation 1712
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:141667926"
variation 1763
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200957611"
variation 1774
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:201765057"
exon 1776..1888
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
variation 1778
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:201336985"
variation 1799
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:139024468"
variation 1800
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:369492720"
variation 1823
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:149469439"
variation 1860
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200438123"
variation 1886
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201360872"
exon 1889..4921
/gene="SYK"
/gene_synonym="p72-Syk"
/inference="alignment:Splign:1.39.8"
STS 1894..2641
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="SYK_1884"
/db_xref="UniSTS:281037"
variation 1904
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202024803"
variation 1905
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200612476"
variation 1910
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:374945682"
variation 1911
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:139348511"
variation 1916
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:145685109"
variation 1934
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200834108"
variation 1936
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:150998279"
variation 1949
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201364356"
variation 1952
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200148300"
variation 1955
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200682995"
variation 1963
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201520390"
variation 1964
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199607948"
variation 1987
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:201191948"
variation 1995
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201001425"
variation 2002
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202243160"
variation 2031
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200070739"
variation 2056
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201179148"
variation 2060
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202035242"
variation 2061
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:191082286"
variation 2078
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201474800"
variation 2095
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202088785"
variation 2142
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:200443955"
variation 2149
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201367588"
variation 2150
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:113175204"
variation 2161
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200786369"
variation 2162
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201177252"
variation 2176
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:199644752"
variation 2181
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:56139234"
variation 2187
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:1804251"
variation 2201
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:201615361"
variation 2210
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200080967"
variation 2226
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200817268"
variation 2227
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:182865904"
variation 2249
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:187420975"
variation 2282
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199888968"
variation 2283
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201168587"
variation 2285
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:1049164"
STS 2291..2431
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="WI-18899"
/db_xref="UniSTS:28988"
variation 2303
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:199927091"
STS 2318..2447
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="RH69035"
/db_xref="UniSTS:21128"
variation 2352
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200937477"
variation 2376
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202179400"
variation 2378
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200478377"
variation 2381
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:41309340"
variation 2401
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:201184094"
variation 2411
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202018238"
variation 2427
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:14979"
variation 2431
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:1804252"
variation 2434
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201236332"
variation 2435
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:41313849"
variation 2461..2462
/gene="SYK"
/gene_synonym="p72-Syk"
/replace=""
/replace="a"
/db_xref="dbSNP:34237652"
variation 2475
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:3087507"
polyA_signal 2477..2482
/gene="SYK"
/gene_synonym="p72-Syk"
variation 2483
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:113304691"
variation 2497
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201054834"
variation 2498
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:3087508"
variation 2504
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:3087506"
polyA_site 2508
/gene="SYK"
/gene_synonym="p72-Syk"
variation 2519
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:199807708"
variation 2564..2565
/gene="SYK"
/gene_synonym="p72-Syk"
/replace=""
/replace="a"
/db_xref="dbSNP:113920845"
variation 2564
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200854897"
variation 2567
/gene="SYK"
/gene_synonym="p72-Syk"
/replace=""
/replace="a"
/db_xref="dbSNP:57651872"
variation 2568
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201993887"
variation 2597
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:199584610"
variation 2599
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:113580142"
variation 2608
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:201935229"
variation 2619
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200082519"
variation 2649
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200996064"
variation 2666
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:192822491"
variation 2675
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:201640049"
variation 2678
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199893313"
variation 2679
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:201228319"
variation 2694
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:202208832"
variation 2707
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:200250756"
variation 2713
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200788246"
variation 2720
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201901573"
variation 2772
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200306296"
variation 2819
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:201170015"
variation 2820
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199593787"
variation 2826
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200233293"
variation 2848
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201530364"
variation 2858
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199757614"
variation 2865
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:200639366"
variation 2873
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201656525"
variation 2874
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:140271666"
variation 2892
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200271297"
variation 2894
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201996237"
variation 2907
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:199910798"
variation 2908
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201033897"
variation 2920
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201904421"
variation 2926
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200062335"
variation 2933
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:158688"
variation 2952
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201766681"
variation 2967
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:184864847"
variation 2976
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201197144"
variation 2980
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202205240"
variation 3024
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:200418572"
variation 3025
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201475559"
variation 3026
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:376917555"
variation 3029
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202172624"
variation 3031
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:12344755"
variation 3057
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:158687"
variation 3088
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:199614233"
variation 3090
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:74847439"
variation 3099
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:138070207"
variation 3113
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:10512203"
variation 3115
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:113367349"
variation 3151
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200684900"
variation 3153
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201846169"
variation 3158
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:158686"
variation 3159
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200678129"
variation 3161
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:201507403"
variation 3177
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:199954919"
variation 3179
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201129087"
variation 3191
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202170530"
variation 3204
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200092376"
variation 3209
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201067892"
STS 3214..3302
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="D8S2279"
/db_xref="UniSTS:473907"
variation 3216
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202049478"
variation 3223
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200169491"
variation 3224
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:201483217"
variation 3225
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:202087399"
STS 3233..3343
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="D10S275"
/db_xref="UniSTS:147992"
variation 3241
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:192259837"
variation 3244
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201450125"
variation 3280
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199763889"
variation 3281
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200961449"
variation 3302
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201471258"
variation 3320
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199623121"
variation 3326
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200404562"
variation 3327
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:158685"
variation 3335
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200068159"
variation 3337
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200689319"
variation 3342
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:138672587"
variation 3357
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:183960220"
variation 3361
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:189425165"
variation 3374
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:142720783"
variation 3375
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199842566"
variation 3383
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:201341496"
variation 3393
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201770050"
variation 3406
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:199924149"
variation 3407..3411
/gene="SYK"
/gene_synonym="p72-Syk"
/replace=""
/replace="aactt"
/db_xref="dbSNP:368223574"
variation 3407
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200933262"
variation 3409
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202178674"
variation 3414
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200488395"
variation 3486
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201111768"
variation 3487
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:5021552"
variation 3507
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202189825"
variation 3510
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:371047374"
variation 3511
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:115363876"
variation 3529
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:192548937"
variation 3532
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199783989"
variation 3541
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:184355645"
variation 3562
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201058837"
variation 3575
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:189146244"
variation 3587
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199768164"
variation 3600
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:181141508"
variation 3607
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201774920"
variation 3631
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:186279193"
variation 3637
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200592316"
variation 3645
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201934148"
variation 3663
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200079558"
variation 3675
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:112868894"
variation 3742
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201711043"
variation 3762
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199822713"
variation 3765
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201323598"
variation 3782
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202054985"
variation 3786
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200437396"
variation 3794
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:17568705"
variation 3795
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201899168"
variation 3811
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200311317"
variation 3829
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201177408"
variation 3833..3834
/gene="SYK"
/gene_synonym="p72-Syk"
/replace=""
/replace="a"
/db_xref="dbSNP:35758629"
variation 3848
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199604777"
variation 3859
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200219989"
variation 3875
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201716941"
variation 3881
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:199714639"
variation 3927
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:148015317"
variation 3928
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200634194"
variation 3934
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201655256"
variation 3940
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:199537078"
variation 3943
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:371399205"
variation 3945
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200782311"
variation 3955
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201768739"
variation 3966
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199976134"
variation 3996
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200655648"
variation 4024
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202076504"
variation 4032
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:10217275"
variation 4034
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:200864082"
variation 4035
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:111798674"
variation 4048
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201771764"
variation 4051
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199911137"
variation 4055
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200984283"
variation 4060
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202058374"
variation 4064
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200440991"
variation 4089
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:115781501"
variation 4096
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202241782"
variation 4107
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200430210"
variation 4108
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201413796"
variation 4134
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:199603436"
variation 4142
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200481350"
variation 4161
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201775735"
variation 4167
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199695443"
variation 4191
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200815743"
variation 4198
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:114553487"
variation 4207
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199914885"
variation 4213
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:200680066"
variation 4223
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201514338"
variation 4237
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199958969"
variation 4270
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200795833"
variation 4284
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:73650275"
variation 4353
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:368631722"
variation 4354
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:200073109"
variation 4362
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:201185795"
variation 4364
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202006211"
variation 4388
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:13559"
variation 4390
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:72729087"
variation 4396
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:201467820"
variation 4398
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202131391"
variation 4405
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200305022"
variation 4420
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201342619"
variation 4458
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199804824"
variation 4469
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200863208"
variation 4470
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201618755"
variation 4476
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199633431"
variation 4477
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:117866558"
variation 4479
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:201616726"
variation 4486
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:199774700"
variation 4491
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:141926409"
variation 4512
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:201639704"
variation 4513
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199863553"
variation 4527
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201200597"
variation 4550
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201761264"
variation 4576
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:199956562"
variation 4577
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200907814"
variation 4591
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:202165739"
variation 4599
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200362937"
variation 4606
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:201255894"
variation 4621
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202010594"
variation 4628
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200244210"
variation 4631
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="g"
/replace="t"
/db_xref="dbSNP:201537770"
variation 4638
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:199792221"
variation 4642
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200278333"
variation 4645
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:189965276"
variation 4646
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199848843"
variation 4664
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="c"
/db_xref="dbSNP:200863059"
variation 4698
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:367775503"
STS 4702..4837
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="RH91425"
/db_xref="UniSTS:84312"
variation 4723
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:201987311"
variation 4730
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:199576591"
STS 4740..4873
/gene="SYK"
/gene_synonym="p72-Syk"
/standard_name="D9S2062"
/db_xref="UniSTS:2175"
variation 4764
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:77417541"
variation 4786
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:8773"
variation 4826
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:200056866"
variation 4850
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="g"
/db_xref="dbSNP:150672706"
variation 4876
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:201710784"
variation 4879
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:199868385"
variation 4882
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="t"
/db_xref="dbSNP:201205439"
variation 4885
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="a"
/replace="g"
/db_xref="dbSNP:202207011"
variation 4888
/gene="SYK"
/gene_synonym="p72-Syk"
/replace="c"
/replace="t"
/db_xref="dbSNP:200425328"
polyA_signal 4892..4897
/gene="SYK"
/gene_synonym="p72-Syk"
polyA_site 4921
/gene="SYK"
/gene_synonym="p72-Syk"
ORIGIN
gactttctggtaaggagaggaggttacggggaacgacgcgctgctttcatgccctttcttgttctaccttcatcggccgaggtggacacctgcgcaggtgtgtgccctccggcccctgaagcatggccagcagcggcatggctgacagcgccaaccacctgcccttctttttcggcaacatcacccgggaggaggcagaagattacctggtccaggggggcatgagtgatgggctttatttgctgcgccagagccgcaactacctgggtggcttcgccctgtccgtggcccacgggaggaaggcacaccactacaccatcgagcgggagctgaatggcacctacgccatcgccggtggcaggacccatgccagccccgccgacctctgccactaccactcccaggagtctgatggcctggtctgcctcctcaagaagcccttcaaccggccccaaggggtgcagcccaagactgggccctttgaggatttgaaggaaaacctcatcagggaatatgtgaagcagacatggaacctgcagggtcaggctctggagcaggccatcatcagtcagaagcctcagctggagaagctgatcgctaccacagcccatgaaaaaatgccttggttccatggaaaaatctctcgggaagaatctgagcaaattgtcctgataggatcaaagacaaatggaaagttcctgatccgagccagagacaacaacggctcctacgccctgtgcctgctgcacgaagggaaggtgctgcactatcgcatcgacaaagacaagacagggaagctctccatccccgagggaaagaagttcgacacgctctggcagctagtcgagcattattcttataaagcagatggtttgttaagagttcttactgtcccatgtcaaaaaatcggcacacagggaaatgttaattttggaggccgtccacaacttccaggttcccatcctgcgtcctcccctgcccaagggaaccggcaagagagtactgtgtcattcaatccgtatgagccagaacttgcaccctgggctgcagacaaaggcccccagagagaagccctacccatggacacagaggtgtacgagagcccctacgcggaccccgaggagatcaggcccaaggaggtttacctggaccgaaagctgctgacgctggaagacaaagaactgggctctggtaattttggaactgtgaaaaagggctactaccaaatgaaaaaagttgtgaaaaccgtggctgtgaaaatactgaaaaacgaggccaatgaccccgctcttaaagatgagttattagcagaagcaaatgtcatgcagcagctggacaacccgtacatcgtgcggatgatcgggatatgcgaggccgagtcctggatgctggttatggagatggcagaacttggtcccctcaataagtatttgcagcagaacagacatgtcaaggataagaacatcatagaactggttcatcaggtttccatgggcatgaagtacttggaggagagcaattttgtgcacagagatctggctgcaagaaatgtgttgctagttacccaacattacgccaagatcagtgatttcggactttccaaagcactgcgtgctgatgaaaactactacaaggcccagacccatggaaagtggcctgtcaagtggtacgctccggaatgcatcaactactacaagttctccagcaaaagcgatgtctggagctttggagtgttgatgtgggaagcattctcctatgggcagaagccatatcgagggatgaaaggaagtgaagtcaccgctatgttagagaaaggagagcggatggggtgccctgcagggtgtccaagagagatgtacgatctcatgaatctgtgctggacatacgatgtggaaaacaggcccggattcgcagcagtggaactgcggctgcgcaattactactatgacgtggtgaactaaccgctcccgcacctgtcggtggctgcctttgatcacaggagcaatcacaggaaaatgtatccagaggaattgattgtcagccacctccctctgccagtcgggagagccaggcttggatggaacatgcccacaacttgtcacccaaagcctgtcccaggactcaccctccacaaagcaaaggcagtcccgggagaaaagacggatggcaggatccaaggggctagctggatttgtttgttttcttgtctgtgtgattttcatacaggttatttttacgatctgtttccaaatccctttcatgtctttccacttctctgggtcccggggtgcatttgttactcatcgggcccagggacattgcagagtggcctagagcactctcaccccaagcggccttttccaaatgcccaaggatgccttagcatgtgactcctgaagggaaggcaaaggcagaggaatttggctgcttctacggccatgagactgatccctggccactgaaaagctttcctgacaataaaaatgttttgaggctttaaaaagaaaatcaagtttgaccagtgcagtttctaagcatgtagccagttaaggaaagaaagaaagaaaaaaaaaaaaggcctggatactgcttttgctgtctctgttatgagatggaagacttacatgtttgtgataaaaggggaccatgagaatgaattggcttggcttactttccccctgaaatcctctctcctgcagactgtcttgaagacctggtgactggtaaataaagccctgcatggaggctgcacagcaggggcaagaggcccatcccccagcatctcactgaggacagcttcaggctgccttcctctgaacgtggtccacaccttcctctcctccacagagagggtgccgccagaatcccctgtcgctttctgtgtctgcaatggggggcagcacagggatcaaagccatctaaagagtttccaaagaaagtattaattcagaacaagccaaagaccctgagcctcaccacaaacaggccttttggagtgtgaatttgagttgaagatacaagatcggagaatgattttctggtcttaactaatcctcatcttcatgtttgatctttaagaagtcatcacccattgatttcagttttgctgtacctcttgaaagttaaagagacatctcagcactttaggaggccgaggcgggtggatcacttgaggtaaggagtttgagactagcctggccaatatggtaaaaccccatctctactaaaaatacaaaaattagccgggcatggtggcatgtgtctgtagtcccagctactcgggaggctgaggcaggagaatcgcttgaacccaggaaacggaggtcgcagtgagccaagatcatgccactgcactccagcttgggcatcacagcgagactctgtcaaaacaaacaaacaaaaaaacaacttaaagaggtaatttagccatcattcttatgccagcagatataaataaacttggacccatctggtcttcagctaaacctgagacattttaaagtgcatggacagccatggacagcaggccctcctctaacaggggatgcaaggcatggagaaagacaatcagtacccaagctcagccacagaagacaggagtcactcatataacttgtgtttagaagtttttggtagccacgcacactttctgaaatcacactatctggtggtttaatcatatttttaaagacagaatccctgagtgctgagcagattctcaaaacacatttagaatccctgaaattagaaagatcaatgacaaaatatctgtcagccaggccacaaacaggtgtaaaattatgaaaggagtggttggatgtgccaagtttggtaaagtggtgactgcatctgagaaagaggctgtgaggctgaactcttggtggcttccttctgtaacttccagagggagtcttcaacacaggccccgtgctcgtaggaatacggtagcacctatgtaggaagtgcgtggagttttctgtcttctttctgtgtgatttttggcctttttatcagcacttctcccctcccaggagcctggggatgccaaacatccagaatgtgatgggacaagatgggggcaggggcctcacctccctgcagaggtccggccaggtctccttgtccctggacaatctcctgagcctctctgcttggtggagcaggcacctgtgtgcagaattcccactgtggccagcacgaggaagtcttttctagtgaaaatgtgtcttgtggtcaggaataattatcctttcccctgtagccaccaaggagggcaaatagagaaaggtaacctaattgaaggattggtcatgtgaaaagggctacatttgggaagctgggaaaggcctccaggcttctagagcagctagcttgggctggattctcatacccaggctgccccttggattgttctacccaagcttttccctggggtctgggctcactccataaggtaaggtgccttttaccttatggtccttctttagcaggtaacaaaggagcatcaggggcaggctgccctggtggcatcacactggctagtgaggccgtgaatatcttgtcccccagcagggccgacagtttctatcacagaaaacagtgtgttcagtggtgaaaatcgttgcatgcatgttttcatctgagcgtgtccttctcccatactccctatcagccagccctgcctgtagctgctgtatggtgattgcacttggacatcagtccaatgactgcaagtcggcctggattttcacttgcagaggctacagctgcattgtcaggtctcccagccctgcagagagctccctccactggttagcagtgtgttgtgttttccattcatttcagaagagctacattgtgtcactggacatttttaaaaactgtgatttttaataaaaatttaaaatttgctttgtgatgaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:6850 -> Molecular function: GO:0004672 [protein kinase activity] evidence: NAS
GeneID:6850 -> Molecular function: GO:0004713 [protein tyrosine kinase activity] evidence: EXP
GeneID:6850 -> Molecular function: GO:0004713 [protein tyrosine kinase activity] evidence: TAS
GeneID:6850 -> Molecular function: GO:0004715 [non-membrane spanning protein tyrosine kinase activity] evidence: IDA
GeneID:6850 -> Molecular function: GO:0004715 [non-membrane spanning protein tyrosine kinase activity] evidence: TAS
GeneID:6850 -> Molecular function: GO:0004716 [receptor signaling protein tyrosine kinase activity] evidence: IEA
GeneID:6850 -> Molecular function: GO:0005178 [integrin binding] evidence: IPI
GeneID:6850 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:6850 -> Molecular function: GO:0005524 [ATP binding] evidence: IEA
GeneID:6850 -> Molecular function: GO:0019901 [protein kinase binding] evidence: IEA
GeneID:6850 -> Biological process: GO:0001525 [angiogenesis] evidence: IEA
GeneID:6850 -> Biological process: GO:0001945 [lymph vessel development] evidence: ISS
GeneID:6850 -> Biological process: GO:0002250 [adaptive immune response] evidence: ISS
GeneID:6850 -> Biological process: GO:0002281 [macrophage activation involved in immune response] evidence: ISS
GeneID:6850 -> Biological process: GO:0002283 [neutrophil activation involved in immune response] evidence: ISS
GeneID:6850 -> Biological process: GO:0002366 [leukocyte activation involved in immune response] evidence: ISS
GeneID:6850 -> Biological process: GO:0002554 [serotonin secretion by platelet] evidence: ISS
GeneID:6850 -> Biological process: GO:0006468 [protein phosphorylation] evidence: ISS
GeneID:6850 -> Biological process: GO:0007159 [leukocyte cell-cell adhesion] evidence: IDA
GeneID:6850 -> Biological process: GO:0007167 [enzyme linked receptor protein signaling pathway] evidence: IEA
GeneID:6850 -> Biological process: GO:0007229 [integrin-mediated signaling pathway] evidence: ISS
GeneID:6850 -> Biological process: GO:0007229 [integrin-mediated signaling pathway] evidence: NAS
GeneID:6850 -> Biological process: GO:0007257 [activation of JUN kinase activity] evidence: IEA
GeneID:6850 -> Biological process: GO:0007596 [blood coagulation] evidence: TAS
GeneID:6850 -> Biological process: GO:0008283 [cell proliferation] evidence: TAS
GeneID:6850 -> Biological process: GO:0009887 [organ morphogenesis] evidence: TAS
GeneID:6850 -> Biological process: GO:0010543 [regulation of platelet activation] evidence: ISS
GeneID:6850 -> Biological process: GO:0018108 [peptidyl-tyrosine phosphorylation] evidence: IEA
GeneID:6850 -> Biological process: GO:0019048 [modulation by virus of host morphology or physiology] evidence: IEA
GeneID:6850 -> Biological process: GO:0019370 [leukotriene biosynthetic process] evidence: IEA
GeneID:6850 -> Biological process: GO:0030168 [platelet activation] evidence: TAS
GeneID:6850 -> Biological process: GO:0030593 [neutrophil chemotaxis] evidence: IDA
GeneID:6850 -> Biological process: GO:0032928 [regulation of superoxide anion generation] evidence: ISS
GeneID:6850 -> Biological process: GO:0033630 [positive regulation of cell adhesion mediated by integrin] evidence: ISS
GeneID:6850 -> Biological process: GO:0038095 [Fc-epsilon receptor signaling pathway] evidence: TAS
GeneID:6850 -> Biological process: GO:0038096 [Fc-gamma receptor signaling pathway involved in phagocytosis] evidence: TAS
GeneID:6850 -> Biological process: GO:0042742 [defense response to bacterium] evidence: ISS
GeneID:6850 -> Biological process: GO:0043306 [positive regulation of mast cell degranulation] evidence: IEA
GeneID:6850 -> Biological process: GO:0043313 [regulation of neutrophil degranulation] evidence: ISS
GeneID:6850 -> Biological process: GO:0043366 [beta selection] evidence: IEA
GeneID:6850 -> Biological process: GO:0045087 [innate immune response] evidence: ISS
GeneID:6850 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
GeneID:6850 -> Biological process: GO:0045401 [positive regulation of interleukin-3 biosynthetic process] evidence: IEA
GeneID:6850 -> Biological process: GO:0045425 [positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process] evidence: IEA
GeneID:6850 -> Biological process: GO:0045579 [positive regulation of B cell differentiation] evidence: IEA
GeneID:6850 -> Biological process: GO:0045588 [positive regulation of gamma-delta T cell differentiation] evidence: IEA
GeneID:6850 -> Biological process: GO:0045780 [positive regulation of bone resorption] evidence: ISS
GeneID:6850 -> Biological process: GO:0046638 [positive regulation of alpha-beta T cell differentiation] evidence: IEA
GeneID:6850 -> Biological process: GO:0046641 [positive regulation of alpha-beta T cell proliferation] evidence: IEA
GeneID:6850 -> Biological process: GO:0046777 [protein autophosphorylation] evidence: IEA
GeneID:6850 -> Biological process: GO:0048514 [blood vessel morphogenesis] evidence: ISS
GeneID:6850 -> Biological process: GO:0050715 [positive regulation of cytokine secretion] evidence: IEA
GeneID:6850 -> Biological process: GO:0050731 [positive regulation of peptidyl-tyrosine phosphorylation] evidence: IEA
GeneID:6850 -> Biological process: GO:0050764 [regulation of phagocytosis] evidence: ISS
GeneID:6850 -> Biological process: GO:0050850 [positive regulation of calcium-mediated signaling] evidence: IEA
GeneID:6850 -> Biological process: GO:0050853 [B cell receptor signaling pathway] evidence: ISS
GeneID:6850 -> Biological process: GO:0070372 [regulation of ERK1 and ERK2 cascade] evidence: ISS
GeneID:6850 -> Biological process: GO:0071226 [cellular response to molecule of fungal origin] evidence: ISS
GeneID:6850 -> Biological process: GO:0090237 [regulation of arachidonic acid secretion] evidence: ISS
GeneID:6850 -> Biological process: GO:0090330 [regulation of platelet aggregation] evidence: ISS
GeneID:6850 -> Cellular component: GO:0005829 [cytosol] evidence: IC
GeneID:6850 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
GeneID:6850 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS
GeneID:6850 -> Cellular component: GO:0019815 [B cell receptor complex] evidence: IEA
GeneID:6850 -> Cellular component: GO:0032009 [early phagosome] evidence: ISS
GeneID:6850 -> Cellular component: GO:0042101 [T cell receptor complex] evidence: IDA
ANNOTATIONS from NCBI Entrez Gene (20130726):
NP_001167639 -> EC 2.7.10.2
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.