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2020-10-24 07:33:06, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001173               9601 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens Rho GTPase activating protein 5 (ARHGAP5), transcript
            variant 2, mRNA.
ACCESSION   NM_001173
VERSION     NM_001173.2  GI:71834860
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9601)
  AUTHORS   Tripathi,B.K. and Zelenka,P.S.
  TITLE     Cdk5-dependent regulation of Rho activity, cytoskeletal
            contraction, and epithelial cell migration via suppression of Src
            and p190RhoGAP
  JOURNAL   Mol. Cell. Biol. 29 (24), 6488-6499 (2009)
   PUBMED   19822667
  REMARK    GeneRIF: Results link Cdk5 to Rho-ROCK signaling via Src and
            p190RhoGAP and implicate Cdk5 in the regulation of cell
            contraction, attachment, and migration.
REFERENCE   2  (bases 1 to 9601)
  AUTHORS   Gen,Y., Yasui,K., Zen,K., Nakajima,T., Tsuji,K., Endo,M.,
            Mitsuyoshi,H., Minami,M., Itoh,Y., Tanaka,S., Taniwaki,M., Arii,S.,
            Okanoue,T. and Yoshikawa,T.
  TITLE     A novel amplification target, ARHGAP5, promotes cell spreading and
            migration by negatively regulating RhoA in Huh-7 hepatocellular
            carcinoma cells
  JOURNAL   Cancer Lett. 275 (1), 27-34 (2009)
   PUBMED   18996642
  REMARK    GeneRIF: ARHGAP5 (the gene encoding p190-B RhoGAP) is a probable
            target for the amplification at 14q12, and p190-B RhoGAP promotes
            cells spreading and migration by negatively regulating RhoA
            activity in Huh-7 hepatocellular carcinoma cells
REFERENCE   3  (bases 1 to 9601)
  AUTHORS   Zhan,X. and Desiderio,D.M.
  TITLE     Nitroproteins from a human pituitary adenoma tissue discovered with
            a nitrotyrosine affinity column and tandem mass spectrometry
  JOURNAL   Anal. Biochem. 354 (2), 279-289 (2006)
   PUBMED   16777052
REFERENCE   4  (bases 1 to 9601)
  AUTHORS   Vargo-Gogola,T., Heckman,B.M., Gunther,E.J., Chodosh,L.A. and
            Rosen,J.M.
  TITLE     P190-B Rho GTPase-activating protein overexpression disrupts ductal
            morphogenesis and induces hyperplastic lesions in the developing
            mammary gland
  JOURNAL   Mol. Endocrinol. 20 (6), 1391-1405 (2006)
   PUBMED   16469769
  REMARK    GeneRIF: precise control of p190-B Rho GTPase-activating protein
            activity is critical for normal branching morphogenesis during
            mammary gland development
REFERENCE   5  (bases 1 to 9601)
  AUTHORS   Blanchetot,C., Chagnon,M., Dube,N., Halle,M. and Tremblay,M.L.
  TITLE     Substrate-trapping techniques in the identification of cellular PTP
            targets
  JOURNAL   Methods 35 (1), 44-53 (2005)
   PUBMED   15588985
REFERENCE   6  (bases 1 to 9601)
  AUTHORS   Chakravarty,G., Roy,D., Gonzales,M., Gay,J., Contreras,A. and
            Rosen,J.M.
  TITLE     P190-B, a Rho-GTPase-activating protein, is differentially
            expressed in terminal end buds and breast cancer
  JOURNAL   Cell Growth Differ. 11 (7), 343-354 (2000)
   PUBMED   10939588
REFERENCE   7  (bases 1 to 9601)
  AUTHORS   Zrihan-Licht,S., Fu,Y., Settleman,J., Schinkmann,K., Shaw,L.,
            Keydar,I., Avraham,S. and Avraham,H.
  TITLE     RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP
            with RasGAP and is involved in breast cancer cell invasion
  JOURNAL   Oncogene 19 (10), 1318-1328 (2000)
   PUBMED   10713673
REFERENCE   8  (bases 1 to 9601)
  AUTHORS   Burbelo,P.D., Miyamoto,S., Utani,A., Brill,S., Yamada,K.M., Hall,A.
            and Yamada,Y.
  TITLE     p190-B, a new member of the Rho GAP family, and Rho are induced to
            cluster after integrin cross-linking
  JOURNAL   J. Biol. Chem. 270 (52), 30919-30926 (1995)
   PUBMED   8537347
REFERENCE   9  (bases 1 to 9601)
  AUTHORS   Foster,R., Hu,K.Q., Shaywitz,D.A. and Settleman,J.
  TITLE     p190 RhoGAP, the major RasGAP-associated protein, binds GTP
            directly
  JOURNAL   Mol. Cell. Biol. 14 (11), 7173-7181 (1994)
   PUBMED   7935432
REFERENCE   10 (bases 1 to 9601)
  AUTHORS   Ellis,C., Moran,M., McCormick,F. and Pawson,T.
  TITLE     Phosphorylation of GAP and GAP-associated proteins by transforming
            and mitogenic tyrosine kinases
  JOURNAL   Nature 343 (6256), 377-381 (1990)
   PUBMED   1689011
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL161665.5, CA945100.1 and
            AL045112.1.
            On Aug 5, 2005 this sequence version replaced gi:4502220.
            
            Summary: Rho GTPase activating protein 5 negatively regulates RHO
            GTPases, a family which may mediate cytoskeleton changes by
            stimulating the hydrolysis of bound GTP. Two transcript variants
            encoding different isoforms have been found for this gene.
            [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice site compared to variant 1. The resulting isoform (b) has
            the same N- and C-termini but is one aa shorter compared to isoform
            a.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns ERS025084,
                              ERS025088 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-147               AL161665.5         145055-145201       c
            148-4032            AL161665.5         128104-131988       c
            4033-4418           CA945100.1         321-706
            4419-4741           AL045112.1         193-515
            4742-9601           AL161665.5         62762-67621         c
FEATURES             Location/Qualifiers
     source          1..9601
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q12"
     gene            1..9601
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="Rho GTPase activating protein 5"
                     /db_xref="GeneID:394"
                     /db_xref="HGNC:675"
                     /db_xref="MIM:602680"
     exon            1..147
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /inference="alignment:Splign:1.39.8"
     variation       126
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377415600"
     exon            148..4032
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /inference="alignment:Splign:1.39.8"
     variation       192..194
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace=""
                     /replace="agg"
                     /db_xref="dbSNP:373668066"
     variation       199
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:55965079"
     variation       227
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:186382575"
     variation       274
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200677078"
     variation       279
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376307600"
     misc_feature    295..297
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="upstream in-frame stop codon"
     CDS             316..4821
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="isoform b is encoded by transcript variant 2;
                     growth factor independent 2; rho GTPase-activating protein
                     5; p105 RhoGAP; p100 RasGAP-associated p105 protein;
                     rho-type GTPase-activating protein 5"
                     /codon_start=1
                     /product="rho GTPase-activating protein 5 isoform b"
                     /protein_id="NP_001164.2"
                     /db_xref="GI:71834861"
                     /db_xref="CCDS:CCDS45095.1"
                     /db_xref="GeneID:394"
                     /db_xref="HGNC:675"
                     /db_xref="MIM:602680"
                     /translation="
MMAKNKEPRPPSYTISIVGLSGTEKDKGNCGVGKSCLCNRFVRSKADEYYPEHTSVLSTIDFGGRVVNNDHFLYWGDIIQNSEDGVECKIHVIEQTEFIDDQTFLPHRSTNLQPYIKRAAASKLQSAEKLMYICTDQLGLEQDFEQKQMPEGKLNVDGFLLCIDVSQGCNRKFDDQLKFVNNLFVQLSKSKKPVIIAATKCDECVDHYLREVQAFASNKKNLLVVETSARFNVNIETCFTALVQMLDKTRSKPKIIPYLDAYKTQRQLVVTATDKFEKLVQTVRDYHATWKTVSNKLKNHPDYEEYINLEGTRKARNTFSKHIEQLKQEHIRKRREEYINTLPRAFNTLLPNLEEIEHLNWSEALKLMEKRADFQLCFVVLEKTPWDETDHIDKINDRRIPFDLLSTLEAEKVYQNHVQHLISEKRRVEMKEKFKKTLEKIQFISPGQPWEEVMCFVMEDEAYKYITEADSKEVYGRHQREIVEKAKEEFQEMLFEHSELFYDLDLNATPSSDKMSEIHTVLSEEPRYKALQKLAPDRESLLLKHIGFVYHPTKETCLSGQNCTDIKVEQLLASSLLQLDHGRLRLYHDSTNIDKVNLFILGKDGLAQELANEIRTQSTDDEYALDGKIYELDLRPVDAKSPYFLSQLWTAAFKPHGCFCVFNSIESLSFIGEFIGKIRTEASQIRKDKYMANLPFTLILANQRDSISKNLPILRHQGQQLANKLQCPFVDVPAGTYPRKFNETQIKQALRGVLESVKHNLDVVSPIPANKDLSEADLRIVMCAMCGDPFSVDLILSPFLDSHSCSAAQAGQNNSLMLDKIIGEKRRRIQITILSYHSSIGVRKDELVHGYILVYSAKRKASMGMLRAFLSEVQDTIPVQLVAVTDSQADFFENEAIKELMTEGEHIATEITAKFTALYSLSQYHRQTEVFTLFFSDVLEKKNMIENSYLSDNTRESTHQSEDVFLPSPRDCFPYNNYPDSDDDTEAPPPYSPIGDDVQLLPTPSDRSRYRLDLEGNEYPIHSTPNCHDHERNHKVPPPIKPKPVVPKTNVKKLDPNLLKTIEAGIGKNPRKQTSRVPLAHPEDMDPSDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIRNSFVNNTQGDEENGFSDRTSKSHGERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRKGRHRGSEEDPLLSPVETWKGGIDNPAITSDQELDDKKMKKKTHKVKEDKKKKKTKNFNPPTRRNWESNYFGMPLQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPDKTERLHALKEIVKKFHPVNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLSTTKIHQSVVETFIQQCQFFFYNGEIVETTNIVAPPPPSNPGQLVEPMVPLQLPPPLQPQLIQPQLQTDPLGII
"
     misc_feature    406..1053
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="P-loop containing Nucleoside Triphosphate
                     Hydrolases; Region: P-loop_NTPase; cl09099"
                     /db_xref="CDD:213113"
     misc_feature    order(406..423,595..597,910..915,919..921,997..1005)
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206648"
     misc_feature    406..420
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="G1 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    490..492
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="G2 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    496..504
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206648"
     misc_feature    order(595..597,784..789)
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206648"
     misc_feature    910..921
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="G4 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    997..1005
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="G5 box; other site"
                     /db_xref="CDD:206648"
     misc_feature    1126..1290
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="Contains two conserved F residues; Region: FF;
                     smart00441"
                     /db_xref="CDD:128718"
     misc_feature    1417..1575
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="Contains two conserved F residues; Region: FF;
                     smart00441"
                     /db_xref="CDD:128718"
     misc_feature    1600..1758
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="Contains two conserved F residues; Region: FF;
                     smart00441"
                     /db_xref="CDD:128718"
     misc_feature    1765..1914
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="Contains two conserved F residues; Region: FF;
                     smart00441"
                     /db_xref="CDD:128718"
     misc_feature    1963..1965
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Nitrated tyrosine; propagated from
                     UniProtKB/Swiss-Prot (Q13017.2); modified site"
     misc_feature    2608..2610
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q13017.2); phosphorylation site"
     misc_feature    3166..3168
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q13017.2); phosphorylation site"
     misc_feature    3217..3219
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q13017.2); phosphorylation site"
     misc_feature    3658..3660
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q13017.2); phosphorylation site"
     misc_feature    3832..3834
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q13017.2); phosphorylation site"
     misc_feature    3841..3843
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q13017.2); phosphorylation site"
     misc_feature    3898..3900
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q13017.2); phosphorylation site"
     misc_feature    3919..3921
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q13017.2); phosphorylation site"
     misc_feature    3919..3921
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    3967..3969
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q13017.2); phosphorylation site"
     misc_feature    3967..3969
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="phosphorylation site"
     misc_feature    4090..4644
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="RhoGAP_p190: RhoGAP (GTPase-activator protein [GAP]
                     for Rho-like small GTPases) domain of p190-like proteins.
                     p190, also named RhoGAP5, plays a role in neuritogenesis
                     and axon branch stability. p190 shows a preference for
                     Rho, over Rac and Cdc42, and...; Region: RhoGAP_p190;
                     cd04373"
                     /db_xref="CDD:63842"
     misc_feature    4126..4647
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="GTPase-activator protein for Rho-like GTPases;
                     Region: RhoGAP; smart00324"
                     /db_xref="CDD:197653"
     misc_feature    order(4201..4203,4315..4317,4327..4329,4534..4536,
                     4543..4548,4615..4617)
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="putative GTPase interaction site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:63842"
     misc_feature    4201..4203
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:63842"
     variation       364
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:17386818"
     variation       375
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:146791896"
     variation       442
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369146124"
     variation       465
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139278127"
     variation       474
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201062895"
     variation       509
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373505990"
     variation       564
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:143497372"
     variation       610
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377715761"
     variation       657
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:377565912"
     variation       669
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:370391316"
     variation       685
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200755411"
     variation       703
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367805928"
     variation       719
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371747331"
     variation       774
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374638293"
     variation       795
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190485053"
     variation       796
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:145904404"
     variation       798
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370059505"
     variation       809
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200498117"
     variation       824
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375076650"
     variation       869
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:369503160"
     variation       927
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144274970"
     variation       956
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369093762"
     variation       1155
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367996747"
     variation       1200
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144586464"
     variation       1214
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371461440"
     variation       1341
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148782993"
     variation       1419
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142697641"
     variation       1489
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372981423"
     variation       1566
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145993763"
     variation       1569
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61747596"
     variation       1625
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:56259828"
     variation       1677
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143684972"
     variation       1680
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:151276606"
     variation       1736
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200111638"
     variation       1753
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201986816"
     variation       1756
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200628183"
     variation       1780
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:78337553"
     variation       1877
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201351112"
     variation       1960
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139228559"
     variation       1991
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149988341"
     variation       2012
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145387405"
     variation       2035
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:142620412"
     variation       2058
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199609559"
     variation       2062
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146911446"
     variation       2098
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181754222"
     variation       2184
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201489307"
     variation       2218
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:115598823"
     variation       2219
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141762175"
     variation       2269
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146396734"
     variation       2271
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377277190"
     variation       2275
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148226075"
     variation       2282
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:200687781"
     variation       2298
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369766568"
     variation       2316
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372988874"
     variation       2325
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:374179893"
     variation       2349
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191278032"
     variation       2360
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372956846"
     variation       2363
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141134108"
     variation       2404
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150293728"
     variation       2457
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377117868"
     variation       2472
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367605056"
     variation       2493
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61739165"
     variation       2523
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:186741221"
     variation       2602
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:189967153"
     variation       2615
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142663482"
     variation       2619
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146041775"
     variation       2620
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370267449"
     variation       2635
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373593195"
     variation       2650
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:139895818"
     variation       2658
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141747142"
     variation       2662
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:200248752"
     variation       2664
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61737878"
     variation       2667
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371137927"
     variation       2669
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148538118"
     variation       2694
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201765085"
     variation       2699
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374527700"
     variation       2798
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:142888518"
     variation       2833
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151030401"
     variation       2868
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140758857"
     variation       2901
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139734756"
     variation       2925
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200739729"
     variation       2937
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147957990"
     variation       2949
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61737869"
     variation       3009
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143191152"
     variation       3016
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150461143"
     variation       3031
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368445681"
     variation       3063
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145372823"
     variation       3092
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148845374"
     variation       3096
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372850172"
     variation       3162
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372395150"
     variation       3169
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:56011706"
     variation       3170
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375310953"
     variation       3173
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151151743"
     variation       3228
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61739174"
     variation       3239
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140808667"
     variation       3252
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144832681"
     variation       3264
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138769686"
     variation       3295
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141239257"
     variation       3322
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61739181"
     variation       3335
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371418384"
     variation       3376
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201859090"
     variation       3387
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:138049187"
     variation       3405
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149587473"
     variation       3409
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200073853"
     variation       3410
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376418547"
     variation       3433
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368781859"
     variation       3448
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374565403"
     variation       3478
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:193025304"
     variation       3500
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147275403"
     variation       3508
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:140666572"
     variation       3541
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200670818"
     variation       3569
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201427084"
     variation       3575
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:367744131"
     variation       3587
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370569198"
     variation       3590
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373639217"
     variation       3596
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144640899"
     variation       3605
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:147527447"
     variation       3607
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140177459"
     variation       3664
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202149589"
     variation       3680
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142991621"
     variation       3758
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374422184"
     variation       3759
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139011417"
     variation       3823
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141066701"
     variation       3866
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:188144262"
     variation       3892
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201734513"
     variation       3896
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149893615"
     variation       3960
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377181913"
     variation       3968
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:149916368"
     variation       4010
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:372091460"
     exon            4033..4177
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /inference="alignment:Splign:1.39.8"
     variation       4068
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:373330466"
     variation       4084
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370086242"
     variation       4102
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:146454039"
     variation       4114
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:61731183"
     exon            4178..4255
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /inference="alignment:Splign:1.39.8"
     variation       4188
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374154091"
     variation       4209
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144611223"
     variation       4215
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188578201"
     exon            4256..4387
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /inference="alignment:Splign:1.39.8"
     variation       4319
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:182392819"
     variation       4342
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371837356"
     variation       4375
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:187384396"
     exon            4388..4493
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /inference="alignment:Splign:1.39.8"
     variation       4394
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371504762"
     variation       4395
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370895550"
     variation       4406
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112118715"
     variation       4408
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138543554"
     variation       4409
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148897080"
     variation       4411
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189213873"
     variation       4464
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143627018"
     STS             4480..4607
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /standard_name="Arhgap5"
                     /db_xref="UniSTS:526932"
     exon            4494..9601
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /inference="alignment:Splign:1.39.8"
     variation       4528
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:112370244"
     STS             4558..4703
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /standard_name="RH18005"
                     /db_xref="UniSTS:32239"
     variation       4579
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:56077784"
     variation       4586
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375679512"
     variation       4600
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371504691"
     variation       4617
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369772813"
     variation       4619
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11551871"
     variation       4624
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:141737585"
     variation       4635
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375933800"
     variation       4664
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184170826"
     variation       4682
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377293078"
     variation       4691
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202041549"
     variation       4729
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200577126"
     variation       4738
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147264826"
     variation       4742
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:139158293"
     variation       4761
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375537995"
     variation       4783
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143148346"
     variation       4791
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149811240"
     variation       4799
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200147073"
     variation       4802
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369779328"
     variation       4818
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:139279589"
     variation       4840
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:192316189"
     variation       4861
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:75664073"
     variation       5228
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375721284"
     variation       5254
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184009419"
     variation       5279
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:188693069"
     variation       5313
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:192582867"
     variation       5344
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:57976485"
     variation       5509
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114957711"
     variation       5531
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:111284027"
     variation       5583
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:45441195"
     variation       5680
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184253112"
     variation       5693
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:3168895"
     variation       5716
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:3178122"
     variation       5780
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368469887"
     polyA_signal    5865..5870
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
     polyA_site      5891
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /experiment="experimental evidence, no additional details
                     recorded"
     variation       5916
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:45512399"
     variation       5989
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111791064"
     variation       6163
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182088962"
     variation       6262
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:186417627"
     variation       6311
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3178124"
     variation       6399
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:376437523"
     variation       6461
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:188767762"
     variation       6505..6506
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:200396089"
     variation       6506
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:45596831"
     variation       6519
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:11551870"
     variation       6779
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373353214"
     variation       6876
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:185364317"
     STS             6926..7049
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /standard_name="RH45106"
                     /db_xref="UniSTS:10594"
     variation       6999
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:115935597"
     variation       7030
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191254361"
     variation       7035
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140094713"
     polyA_signal    7068..7073
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
     polyA_site      7090
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /experiment="experimental evidence, no additional details
                     recorded"
     polyA_signal    7319..7324
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
     polyA_site      7338
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /experiment="experimental evidence, no additional details
                     recorded"
     variation       7355
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372782800"
     variation       7412
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:374885208"
     variation       7472
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:7152756"
     variation       7544
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:143719152"
     variation       7551
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:185877684"
     STS             7676..7802
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /standard_name="RH104330"
                     /db_xref="UniSTS:98655"
     variation       7702
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191217442"
     variation       7727..7730
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace=""
                     /replace="taat"
                     /db_xref="dbSNP:374103451"
     variation       7776
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:183338782"
     variation       7875
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:187937575"
     variation       7891
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:76071667"
     variation       7968
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145507663"
     variation       7972
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191970842"
     variation       8105
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147751698"
     variation       8190
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148788825"
     variation       8270
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:183084810"
     variation       8361
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:79332474"
     variation       8420
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:188790974"
     variation       8633
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150942994"
     variation       8783
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368796055"
     variation       8816
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:192638225"
     variation       8884
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144680817"
     variation       9000
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:185070121"
     variation       9070
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:189125052"
     variation       9097
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146681076"
     variation       9236
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:140352285"
     variation       9239
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376546766"
     variation       9278
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371480073"
     variation       9291
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:374393715"
     variation       9296
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:114509182"
     variation       9341
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376045217"
     variation       9563
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145415255"
     variation       9569
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:192723174"
     polyA_signal    9577..9582
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
     polyA_site      9601
                     /gene="ARHGAP5"
                     /gene_synonym="GFI2; p190-B; p190BRhoGAP; RhoGAP5"
ORIGIN      
ctcggtgagcgcgccgaggaagagaggcgagcggagagtggaggaggaggcggcggcggcgggagcggtccccaggaatgtcgctgccgccgccaccgccggggccgctgccgttgaggaggagacggaggagaccgacgttgttaggaagatgatccctatgatcttgaagatgtttctgcacagaaatgagggaaatacaaagaaccaaatacagttctgaaatttgggatctgtattttgagatgattttattttcagaatgagaagcatatctggttacctttatgaatgtagagacatgagaagagagttatgatggcaaaaaacaaagagcctcgtcccccatcctataccatcagtatagttggactctctgggactgaaaaagacaaaggtaactgtggagttggaaagtcttgtttgtgcaatagatttgtacgctcaaaagcagatgaatattatccagagcatacttctgtgcttagcaccattgactttggaggacgagtagtaaacaatgatcactttttgtactggggtgacataatacaaaatagtgaagatggagtagaatgcaaaattcatgtcattgaacaaacagagttcattgatgaccagactttcttgcctcatcggagtacgaatttgcaaccatatataaaacgtgcagctgcatctaaattgcagtcagcagaaaaactaatgtacatttgcactgatcagctaggcttagaacaagactttgaacagaagcaaatgcctgaagggaagctcaacgtagatggatttttattatgcattgatgtaagtcaaggatgcaataggaagtttgatgatcaacttaaatttgtgaataacctttttgtccagttatcaaaatcaaaaaaacctgtaataatagcagcaactaaatgtgatgaatgcgtggatcattatcttagagaagttcaggcatttgcttcaaataaaaagaaccttcttgtagtggaaacatcagcacgatttaatgtcaacattgaaacatgttttactgcactggtacaaatgttggataaaactcgtagcaagcctaaaattattccctatttggatgcttataaaacacagagacaacttgttgtcacagcaacagataagtttgaaaaacttgtgcagactgtgagagattatcatgcaacttggaaaactgttagtaataaattaaaaaatcatcctgattatgaagaatacatcaacttagagggaacaagaaaggccagaaatacattctcaaaacatatagaacaacttaaacaggaacatataagaaaaaggagagaagagtatataaatactttaccaagagcttttaacactcttttgccaaatctagaagagattgaacatttgaattggtcagaagctttgaagttaatggaaaagagagcagatttccagttatgttttgtggtgctagaaaaaactccttgggatgaaactgaccatatagacaaaattaatgataggcggattccatttgacctcctgagcactttagaagctgaaaaagtctatcagaaccatgtacagcatctgatatccgagaagaggagggtggaaatgaaggaaaaattcaaaaagactttggaaaaaattcaattcatttcaccagggcagccatgggaggaagttatgtgctttgttatggaggatgaagcctacaaatatatcactgaggctgatagcaaagaggtatatggtaggcatcagcgagaaatagttgaaaaagccaaagaagagtttcaagaaatgctttttgagcattctgaacttttttatgatttagatcttaatgcaacacctagttcagataaaatgagtgaaattcatacagttctgagtgaagaacctagatataaagctttacagaaacttgcacctgatagggaatcccttctacttaagcatataggatttgtttatcatcccactaaagaaacatgtcttagtggccaaaattgtacagacattaaagtggagcagttacttgctagtagtcttttacagttggatcatggccgcttaagattatatcacgatagtaccaatatagataaagttaacctttttattttagggaaggatggccttgcccaagaactagcaaatgagataaggacacaatccactgatgatgagtatgccttagatggaaaaatttatgaacttgatcttcggccggttgatgccaaatcgccttactttttgagtcagttatggactgccgcctttaaaccacatgggtgcttctgtgtatttaattccattgagtcattgagttttattggggaatttattgggaaaataagaactgaagcttctcagatcagaaaagataaatacatggctaatcttccatttacattaattctggctaatcagagagattccattagtaagaatctaccaattctcaggcaccaagggcagcagttggcaaacaagttgcaatgtccttttgtagatgtacctgctggtacatatcctcgtaaatttaatgaaacccaaataaagcaagctctcagaggagtattggaatcagttaaacacaatttggatgtggtgagcccaattcctgccaataaggacttatcagaagctgacttgagaattgtcatgtgcgccatgtgtggagatccatttagtgtggatcttattctttcacccttccttgattctcattcttgcagtgctgctcaagctggacagaataattccctaatgcttgataaaatcattggtgaaaaaaggaggcgaatacagatcacaatattatcataccactcttcaattggagtaagaaaagatgaactagttcatgggtatatattagtttactctgcaaaacggaaagcttcgatgggaatgcttcgagcatttctatcagaagttcaagacaccattcctgtacagctggtggcagttactgacagccaagcagatttttttgaaaatgaggctatcaaagagttaatgactgaaggagaacacattgcaactgagatcactgctaaatttacagcactgtattctttatctcagtatcatcggcaaactgaggtctttactctgttttttagtgatgttctagagaaaaaaaatatgatagaaaattcttatttgtctgataatacaagggaatcaacccatcaaagtgaagatgtttttctaccatctcccagagactgttttccctataataactaccctgattcagatgatgacacagaagcaccacctccttatagtccaattggggatgatgtacagttgcttccaacacctagtgaccgttccagatatagattagatttggaaggaaatgagtatcctattcatagtaccccaaactgtcatgaccatgaacgcaaccataaagtgcctccacctattaaacctaaaccagttgtacctaagacaaatgtgaaaaaactcgatccaaaccttttaaaaacaattgaagctggtattggtaaaaatccaagaaagcagacttcccgggtgcctttggcacatcctgaagatatggatccttcagataactatgcggaacccattgatacaattttcaaacagaagggctattctgatgagatttatgttgtcccagatgatagtcaaaatcgtattaaaattcgaaactcatttgtaaataacacccaaggagatgaagaaaatgggttttctgatagaacctcaaaaagtcatggggaacggaggccttcaaaatacaaatataaatctaaaaccttgtttagtaaagccaagtcatactatagaagaacacattcagatgccagtgatgatgaggctttcaccacttctaaaacaaaaagaaaaggaagacatcgtggaagtgaagaagatccacttctttctcctgttgaaacttggaaaggtggtattgataatcctgcaatcacttctgaccaggagttagatgataagaagatgaagaagaaaacccacaaagtgaaagaagataaaaagaaaaagaaaactaagaacttcaatccaccaacacgtagaaattgggaaagtaattactttgggatgcccctccaggatctggttacagctgagaagcccataccactatttgttgagaaatgtgtggaatttattgaagatacagggttatgtaccgaaggactctaccgtgtcagcgggaataaaactgaccaagacaatattcaaaagcagtttgatcaagatcataatatcaatctagtgtcaatggaagtaacagtaaatgctgtagctggagcccttaaagctttctttgcagatctgccagatcctttaattccatattctcttcatccagaactattggaagcagcaaaaatcccggataaaacagaacgtcttcatgccttgaaagaaattgttaagaaatttcatcctgtaaactatgatgtattcagatacgtgataacacatctaaacagggttagtcagcaacataaaatcaacctaatgacagcagacaacttatccatctgtttttggccaaccttgatgagacctgattttgaaaatcgagagtttctgtctactactaagattcatcaatctgttgttgaaacattcattcagcagtgtcagtttttcttttacaatggagaaattgtagaaacgacaaacattgtggctcctccaccaccttcaaacccaggacagttggtggaaccaatggtgccacttcagttgccgccaccattgcaacctcagctgatacaaccacaattacaaacggatcctcttggtattatatgagtaggaagtgattgcaaacaggctggatttggacaaaaagcaaatctagacatgcatgtttcagggttcagtagtatacttcatgtttcatacagataattcacattcaaaattacattttctctttgaactagatggtattccttattcacttacattacaaatctaagaccatgtgataagcatgactggagaggtttaatttttataaacaaaaatagctataaagtacaaagctgctgctgcatgcaaccttattgcaatcagtatatcattcctgtggcaatttctgtcaccttatattgtgaataaaatttttctatagaaattaaatgatttaaaaactcacctatatgaaacatttaatgcttttcagcctgctttctggctgattttgttatttgatgtgctaatttgggcaacttaatttacattctggcagtcggtgtagataactaaaagcccagttaagtattttataatttcaggctactgaggccatgcttgggatgttgtttgaaagaaagaaaaaatacacttgacatatttcacatttctgtaccttcatctttacttccaagtaaacccgtggatgatttgatgagggataaatgaacctatttcttttacacacataccaaggacatgcttgtggctaaagtgagttgataatgttgtgcaaaggatagttgtcaccaactcatttctttatggtccataatgaaataaaaattttgtatactgttaattctgtaaacagatgcatgttcaaaagatctatgatggtcttgtaatcttaatctaatatattttagatattttaattttttccctcttggggaacacatttagtatagtgtagaaaatacttccatgacattttcatataaggttatataacttttcatacataaacatgaaatttgttgtagaaaattctttaaaccaaacatttaaatctaggacttcaatttaatttgttccttgaatctatttttatgtggcccttaaaaaatatccaaaaaacccattgctaatatagcaataaaaatactttgggtactgacagactctttggagtgtttatattacaaatttgtattcatattcttttctgtgatgtgttgtactaaaatccaaaatggcttttgcaccatttttaagccaattttttcctttgatgttggtaccagaattactataagtgactgctgcttttgggggtaaacattttgttagtgaagataaaaccagaacactaaattatggataaaattttcagaataggtggcacaggtaaatttcactaggttatattttgtgtagtaaagaaaaaaattatttggtcaatgttatcttaattcatactacaatttaagattatcttatgtgtattatagtaaatagatgattttcagattcaaggctcctaagagtttgatttgctctgttttttcctaaaataaatattgtctctcccaactgttaagttctaggtattgtacttccaattttaacttcagaaccaagatgttggcatgaaccaggctgctgttgaagtacatgtatattataaattatcttatttgtgttatactcttacatgttatcttttctaagaaaacaaagtccctattattcctattgcaaagcacacaggaattaagaaagtacagtaatttttaaaaaaaaatccggtaaatgtagtattcttaacctgttctatattacttatacctattgtctatatagctttaatttatagttgtcagtttaactattggcatgtctggcaaagaaaattaaactttaagagttttataaactgtttctaggttgctaaagaatttatttttctactatatatggtatagacaaagcatcaaactatgtacaggaaaaaagcctgactatttctatttggaagtaggctgaaaagagaattttcaaaactgttcgtgtcttcagttcattctgtcataactttgctattgtaatatgtgaataccagtttatttaagctgttctcttttatactgtattaatttaatgttcatctgcgtttagtaccatttttgttattaaaactggcatttaccgtttttcacattaacccaccttgcaccttcccccaaacttatctccacttttctatgcattctatcattgatttgacacacttcatagtgagtcatttaaatactctacgtttggttcaattaaccagtaggttacagttattgaaaattaaagtacagtttaaagctcagtctgttacactgaattgattgtgtttgtttttgccaagggtttagatatgcttttaaatattagaaacatctaagaacagaataacataattaaacttttttctggtaagttactggaaggtttcactgtttagggacctatcatatgagacttcttaaaggattaaaagaataggatagtctcataattgtgagtaaacatcaaggcattatattttacaatactgaataaaatttcatctacacacatgttgccattgtttcatttaaggttcagtgcttatagttaactacaatattggacctaacaggatctagattagcaatataaagaagcatagtggtactctgtttcacactttcagtagatttattagaagtcaaattctattcaacagacacttattaggatatacaactaatttaagaataaaattccaggcacaatatattttttttaaatggtatttgttagtagtgcttcttccccttaacatttacagtgtaaatactgcaggtaaccgcaatctaagttagccaaaaagcagctttttttcccatactgtatgtaaataatgtagacctgggtttttttgtttatttgggtttgtttttttttttgaggtactggaatctaattaatatctcttaggtatcaacaaaagggaacaattggaatgagaatttaggccttagcttccatggtgatttttagttttttatacagtaataattgtgatgctatttgtcaactggatataaatacacatataattttaaaaagtcaaaagtgcttttgtttctttgtttaatgtaatttttgtgcttcacctacaggatgctgcagtaaattaaatatcagtgaagcttctgatgtataaagaatgctatgaataaaacattaagaagctgtgtaattttaagttatagttgcctctatttttaccatttcattggtaaaaattagctaatttttttcaagtgaaatgaaaaataaaaatataaatttatcaatatgatggaaatcttattaaggagatgtattattgaattttcactgtacctgaaaaggagattcaaaattttttctggggatgtatataggtgaaaatttgattttttaaattatcaggaaaacaagataatgcacagatttctaagactaagatcttacctggatgtgatttttgagctgtggctagacattctttagagccactggaaatattttgaaaactattctagttatagcagagctgctaatattaacgaatatatttgtgtcttcatggtttgtgactattaggccaaattttgtggtatatgttgtcagtctggatctggtgaggtctgttcaacatgaatctttgtgttatcttgaatttagtagtttcaaggtacttaaattcttaacagtttctaatttgtttcaatacatatgggacatggttgatttttttactgtattagaactcttggaagttcttagccttttcaggttatgaaatacctgaaagtaaaattttctaagatttaataagggaagatactattcaaatcattttcttaggatagcatctttacatacaatgagaggattgtacaagcattaatctcatattccaacatccagttacttgatgtgatccaagtaccctggtctttttgaagcagttaaaatctaattaattaactttgggagtcttcactattcaattgatcctcatcattgtcctatttgcatgactccattttttcctccactatatgagttttctttgtcagggggagaggagtgggaagagtcacagaatctcatattcacatcttaattaaattgtgtgaaattagtcttttgtggaaattctgtaggcagtatgattttgaaaagctaaccaatgataattagcattttagttaatactaaatgcataaaattataacccttgaaattaatttggtgctggcagttctggtttagtcatttttaccagtagttagtagtattaagacctgcagtatatgcactttttgagtagctgtcaaataattgtagttgagaaacaacttgtttattctcacaattcagattttctattcagttttgtctcaaatagtaagttattgtgaacaatttaataacggccctcctgttctagtttgcctaatattttagttaagatttagtgttttaacctatttttttaagtttattttttgtattagattttatttgaataagttatgtgggtttagtaattgacctatttattcattgcttcactaattcatccagattagttttaagtgtgtatatgtatttgctcaccagatcattttcttgggaccttgaactgtgaatgttttgtcctaaccatttaatattttctaggtacttgctgcaagttcttgaactattttaccagctttaactttggggctcttagtttcttttctccagattcttgttattttattttatccaaataaatatttaggtgttctaagaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:394 -> Molecular function: GO:0003924 [GTPase activity] evidence: TAS
            GeneID:394 -> Molecular function: GO:0005100 [Rho GTPase activator activity] evidence: TAS
            GeneID:394 -> Molecular function: GO:0005525 [GTP binding] evidence: IEA
            GeneID:394 -> Molecular function: GO:0042169 [SH2 domain binding] evidence: IPI
            GeneID:394 -> Biological process: GO:0002053 [positive regulation of mesenchymal cell proliferation] evidence: IEA
            GeneID:394 -> Biological process: GO:0006184 [GTP catabolic process] evidence: TAS
            GeneID:394 -> Biological process: GO:0007155 [cell adhesion] evidence: TAS
            GeneID:394 -> Biological process: GO:0007264 [small GTPase mediated signal transduction] evidence: TAS
            GeneID:394 -> Biological process: GO:0007266 [Rho protein signal transduction] evidence: TAS
            GeneID:394 -> Biological process: GO:0008361 [regulation of cell size] evidence: IEA
            GeneID:394 -> Biological process: GO:0030335 [positive regulation of cell migration] evidence: IEA
            GeneID:394 -> Biological process: GO:0032321 [positive regulation of Rho GTPase activity] evidence: TAS
            GeneID:394 -> Biological process: GO:0051056 [regulation of small GTPase mediated signal transduction] evidence: TAS
            GeneID:394 -> Cellular component: GO:0005737 [cytoplasm] evidence: TAS
            GeneID:394 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:394 -> Cellular component: GO:0016020 [membrane] evidence: IEA

by @meso_cacase at DBCLS
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