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2020-10-24 06:53:29, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001172435            4939 bp    mRNA    linear   PRI 12-MAY-2013
DEFINITION  Homo sapiens RAB3 GTPase activating protein subunit 1 (catalytic)
            (RAB3GAP1), transcript variant 1, mRNA.
ACCESSION   NM_001172435
VERSION     NM_001172435.1  GI:289547211
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4939)
  AUTHORS   Handley,M.T. and Aligianis,I.A.
  TITLE     RAB3GAP1, RAB3GAP2 and RAB18: disease genes in Micro and Martsolf
            syndromes
  JOURNAL   Biochem. Soc. Trans. 40 (6), 1394-1397 (2012)
   PUBMED   23176487
  REMARK    GeneRIF: Micro syndrome has been associated with causative
            mutations in three disease genes: RAB3GAP1, RAB3GAP2 and RAB18.
            Martsolf syndrome has been associated with a mutation in
            RAB3GAP2.[Review]
            Review article
REFERENCE   2  (bases 1 to 4939)
  AUTHORS   Li,X., Bykhovskaya,Y., Haritunians,T., Siscovick,D., Aldave,A.,
            Szczotka-Flynn,L., Iyengar,S.K., Rotter,J.I., Taylor,K.D. and
            Rabinowitz,Y.S.
  TITLE     A genome-wide association study identifies a potential novel gene
            locus for keratoconus, one of the commonest causes for corneal
            transplantation in developed countries
  JOURNAL   Hum. Mol. Genet. 21 (2), 421-429 (2012)
   PUBMED   21979947
REFERENCE   3  (bases 1 to 4939)
  AUTHORS   Yildirim,M.S., Zamani,A.G. and Bozkurt,B.
  TITLE     Warburg micro syndrome in two children from a highly inbred Turkish
            family
  JOURNAL   Genet. Couns. 23 (2), 169-174 (2012)
   PUBMED   22876574
  REMARK    GeneRIF: The RAB3GAP gene encodes a protein which is a key
            regulator of the Rab3 pathway implicated in exocytic release of
            ocular and neurodevleopmental trophic factors.
REFERENCE   4  (bases 1 to 4939)
  AUTHORS   Dursun,F., Guven,A. and Morris-Rosendahl,D.
  TITLE     Warburg Micro syndrome
  JOURNAL   J. Pediatr. Endocrinol. Metab. 25 (3-4), 379-382 (2012)
   PUBMED   22768674
  REMARK    GeneRIF: Mutation in RAB3GAP1 is associated with warburg micro
            syndrome.
REFERENCE   5  (bases 1 to 4939)
  AUTHORS   Teslovich,T.M., Musunuru,K., Smith,A.V., Edmondson,A.C.,
            Stylianou,I.M., Koseki,M., Pirruccello,J.P., Ripatti,S.,
            Chasman,D.I., Willer,C.J., Johansen,C.T., Fouchier,S.W., Isaacs,A.,
            Peloso,G.M., Barbalic,M., Ricketts,S.L., Bis,J.C., Aulchenko,Y.S.,
            Thorleifsson,G., Feitosa,M.F., Chambers,J., Orho-Melander,M.,
            Melander,O., Johnson,T., Li,X., Guo,X., Li,M., Shin Cho,Y., Jin
            Go,M., Jin Kim,Y., Lee,J.Y., Park,T., Kim,K., Sim,X., Twee-Hee
            Ong,R., Croteau-Chonka,D.C., Lange,L.A., Smith,J.D., Song,K., Hua
            Zhao,J., Yuan,X., Luan,J., Lamina,C., Ziegler,A., Zhang,W.,
            Zee,R.Y., Wright,A.F., Witteman,J.C., Wilson,J.F., Willemsen,G.,
            Wichmann,H.E., Whitfield,J.B., Waterworth,D.M., Wareham,N.J.,
            Waeber,G., Vollenweider,P., Voight,B.F., Vitart,V.,
            Uitterlinden,A.G., Uda,M., Tuomilehto,J., Thompson,J.R., Tanaka,T.,
            Surakka,I., Stringham,H.M., Spector,T.D., Soranzo,N., Smit,J.H.,
            Sinisalo,J., Silander,K., Sijbrands,E.J., Scuteri,A., Scott,J.,
            Schlessinger,D., Sanna,S., Salomaa,V., Saharinen,J., Sabatti,C.,
            Ruokonen,A., Rudan,I., Rose,L.M., Roberts,R., Rieder,M.,
            Psaty,B.M., Pramstaller,P.P., Pichler,I., Perola,M., Penninx,B.W.,
            Pedersen,N.L., Pattaro,C., Parker,A.N., Pare,G., Oostra,B.A.,
            O'Donnell,C.J., Nieminen,M.S., Nickerson,D.A., Montgomery,G.W.,
            Meitinger,T., McPherson,R., McCarthy,M.I., McArdle,W., Masson,D.,
            Martin,N.G., Marroni,F., Mangino,M., Magnusson,P.K., Lucas,G.,
            Luben,R., Loos,R.J., Lokki,M.L., Lettre,G., Langenberg,C.,
            Launer,L.J., Lakatta,E.G., Laaksonen,R., Kyvik,K.O., Kronenberg,F.,
            Konig,I.R., Khaw,K.T., Kaprio,J., Kaplan,L.M., Johansson,A.,
            Jarvelin,M.R., Janssens,A.C., Ingelsson,E., Igl,W., Kees
            Hovingh,G., Hottenga,J.J., Hofman,A., Hicks,A.A., Hengstenberg,C.,
            Heid,I.M., Hayward,C., Havulinna,A.S., Hastie,N.D., Harris,T.B.,
            Haritunians,T., Hall,A.S., Gyllensten,U., Guiducci,C., Groop,L.C.,
            Gonzalez,E., Gieger,C., Freimer,N.B., Ferrucci,L., Erdmann,J.,
            Elliott,P., Ejebe,K.G., Doring,A., Dominiczak,A.F., Demissie,S.,
            Deloukas,P., de Geus,E.J., de Faire,U., Crawford,G., Collins,F.S.,
            Chen,Y.D., Caulfield,M.J., Campbell,H., Burtt,N.P.,
            Bonnycastle,L.L., Boomsma,D.I., Boekholdt,S.M., Bergman,R.N.,
            Barroso,I., Bandinelli,S., Ballantyne,C.M., Assimes,T.L.,
            Quertermous,T., Altshuler,D., Seielstad,M., Wong,T.Y., Tai,E.S.,
            Feranil,A.B., Kuzawa,C.W., Adair,L.S., Taylor,H.A. Jr.,
            Borecki,I.B., Gabriel,S.B., Wilson,J.G., Holm,H.,
            Thorsteinsdottir,U., Gudnason,V., Krauss,R.M., Mohlke,K.L.,
            Ordovas,J.M., Munroe,P.B., Kooner,J.S., Tall,A.R., Hegele,R.A.,
            Kastelein,J.J., Schadt,E.E., Rotter,J.I., Boerwinkle,E.,
            Strachan,D.P., Mooser,V., Stefansson,K., Reilly,M.P., Samani,N.J.,
            Schunkert,H., Cupples,L.A., Sandhu,M.S., Ridker,P.M., Rader,D.J.,
            van Duijn,C.M., Peltonen,L., Abecasis,G.R., Boehnke,M. and
            Kathiresan,S.
  TITLE     Biological, clinical and population relevance of 95 loci for blood
            lipids
  JOURNAL   Nature 466 (7307), 707-713 (2010)
   PUBMED   20686565
REFERENCE   6  (bases 1 to 4939)
  AUTHORS   Rodriguez Criado,G., Rufo,M. and Gomez de Terreros,I.
  TITLE     A second family with Micro syndrome
  JOURNAL   Clin. Dysmorphol. 8 (4), 241-245 (1999)
   PUBMED   10532171
REFERENCE   7  (bases 1 to 4939)
  AUTHORS   Oishi,H., Sasaki,T., Nagano,F., Ikeda,W., Ohya,T., Wada,M., Ide,N.,
            Nakanishi,H. and Takai,Y.
  TITLE     Localization of the Rab3 small G protein regulators in nerve
            terminals and their involvement in Ca2+-dependent exocytosis
  JOURNAL   J. Biol. Chem. 273 (51), 34580-34585 (1998)
   PUBMED   9852129
REFERENCE   8  (bases 1 to 4939)
  AUTHORS   Nagano,F., Sasaki,T., Fukui,K., Asakura,T., Imazumi,K. and Takai,Y.
  TITLE     Molecular cloning and characterization of the noncatalytic subunit
            of the Rab3 subfamily-specific GTPase-activating protein
  JOURNAL   J. Biol. Chem. 273 (38), 24781-24785 (1998)
   PUBMED   9733780
REFERENCE   9  (bases 1 to 4939)
  AUTHORS   Fukui,K., Sasaki,T., Imazumi,K., Matsuura,Y., Nakanishi,H. and
            Takai,Y.
  TITLE     Isolation and characterization of a GTPase activating protein
            specific for the Rab3 subfamily of small G proteins
  JOURNAL   J. Biol. Chem. 272 (8), 4655-4658 (1997)
   PUBMED   9030515
REFERENCE   10 (bases 1 to 4939)
  AUTHORS   Warburg,M., Sjo,O., Fledelius,H.C. and Pedersen,S.A.
  TITLE     Autosomal recessive microcephaly, microcornea, congenital cataract,
            mental retardation, optic atrophy, and hypogenitalism. Micro
            syndrome
  JOURNAL   Am. J. Dis. Child. 147 (12), 1309-1312 (1993)
   PUBMED   8249951
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA333844.1, BC071602.1 and
            AC017031.10.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: This gene encodes the catalytic subunit of a Rab GTPase
            activating protein. The encoded protein forms a heterodimer with a
            non-catalytic subunit to specifically regulate the activity of
            members of the Rab3 subfamily of small G proteins. This protein
            mediates the hydrolysis of GTP bound Rab3 to the GDP bound form.
            Mutations in this gene are associated with Warburg micro syndrome.
            Alternate splicing results in multiple transcript
            variants.[provided by RefSeq, Feb 2010].
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC071602.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025082, ERS025084 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                DA333844.1         1-33
            34-664              BC071602.1         1-631
            665-3994            BC071602.1         633-3962
            3995-4939           AC017031.10        4484-5428
FEATURES             Location/Qualifiers
     source          1..4939
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q21.3"
     gene            1..4939
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /note="RAB3 GTPase activating protein subunit 1
                     (catalytic)"
                     /db_xref="GeneID:22930"
                     /db_xref="HGNC:17063"
                     /db_xref="MIM:602536"
     exon            1..61
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       12
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200628274"
     variation       31
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375796483"
     variation       36
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:367986269"
     variation       40
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202050016"
     CDS             44..3010
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     rab3-GAP p130; RAB3 GTPase-activating protein 130 kDa
                     subunit"
                     /codon_start=1
                     /product="rab3 GTPase-activating protein catalytic subunit
                     isoform 1"
                     /protein_id="NP_001165906.1"
                     /db_xref="GI:289547212"
                     /db_xref="CCDS:CCDS54402.1"
                     /db_xref="GeneID:22930"
                     /db_xref="HGNC:17063"
                     /db_xref="MIM:602536"
                     /translation="
MAADSEPESEVFEITDFTTASEWERFISKVEEVLNDWKLIGNSLGKPLEKGIFTSGTWEEKSDEISFADFKFSVTHHYLVQESTDKEGKDELLEDVVPQSMQDLLGMNNDFPPRAHCLVRWYGLREFVVIAPAAHSDAVLSESKCNLLLSSVSIALGNTGCQVPLFVQIHHKWRRMYVGECQGPGVRTDFEMVHLRKVPNQYTHLSGLLDIFKSKIGCPLTPLPPVSIAIRFTYVLQDWQQYFWPQQPPDIDALVGGEVGGLEFGKLPFGACEDPISELHLATTWPHLTEGIIVDNDVYSDLDPIQAPHWSVRVRKAENPQCLLGDFVTEFFKICRRKESTDEILGRSAFEEEGKETADITHALSKLTEPASVPIHKLSVSNMVHTAKKKIRKHRGVEESPLNNDVLNTILLFLFPDAVSEKPLDGTTSTDNNNPPSESEDYNLYNQFKSAPSDSLTYKLALCLCMINFYHGGLKGVAHLWQEFVLEMRFRWENNFLIPGLASGPPDLRCCLLHQKLQMLNCCIERKKARDEGKKTSASDVTNIYPGDAGKAGDQLVPDNLKETDKEKGEVGKSWDSWSDSEEEFFECLSDTEELKGNGQESGKKGGPKEMANLRPEGRLYQHGKLTLLHNGEPLYIPVTQEPAPMTEDLLEEQSEVLAKLGTSAEGAHLRARMQSACLLSDMESFKAANPGCSLEDFVRWYSPRDYIEEEVIDEKGNVVLKGELSARMKIPSNMWVEAWETAKPIPARRQRRLFDDTREAEKVLHYLAIQKPADLARHLLPCVIHAAVLKVKEEESLENISSVKKIIKQIISHSSKVLHFPNPEDKKLEEIIHQITNVEALIARARSLKAKFGTEKCEQEEEKEDLERFVSCLLEQPEVLVTGAGRGHAGRIIHKLFVNAQRLTESSDEAAAMTPPEEELKRMGSPEERRQNSVSDFPPPAGREFILRTTVPRPAPYSKALPQRMYSVLTKEDFRLAGAFSSDTSFF
"
     misc_feature    1865..2350
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /note="Rab3 GTPase-activating protein catalytic subunit;
                     Region: Rab3-GTPase_cat; pfam13890"
                     /db_xref="CDD:206061"
     variation       51
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371637983"
     exon            62..117
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       89
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141518860"
     variation       111
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145829300"
     exon            118..193
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       137
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143078664"
     variation       167
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372830337"
     exon            194..326
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       213
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139464896"
     variation       227
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:148441684"
     variation       260
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:372673436"
     variation       278
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200332256"
     variation       283
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145219231"
     variation       290
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:202184859"
     exon            327..405
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       340
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200902906"
     variation       344
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369370987"
     variation       362
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151096019"
     variation       400
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:73959261"
     exon            406..525
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       416
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200250746"
     variation       440
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371640817"
     variation       454
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140929274"
     variation       466
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145748693"
     variation       469
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201758067"
     variation       493
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373908112"
     variation       517
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:180819794"
     exon            526..691
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       553
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200315019"
     variation       649
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145762340"
     variation       653
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:149466854"
     exon            692..791
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       712
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:76927619"
     variation       744
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199513495"
     variation       780
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372760255"
     exon            792..873
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       855
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191211045"
     variation       859
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199898437"
     variation       869
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150727606"
     exon            874..942
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       889
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188770482"
     variation       893
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148190655"
     variation       922
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143547678"
     variation       923
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377322603"
     variation       925
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368785012"
     exon            943..1016
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       956
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116775947"
     exon            1017..1109
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       1049
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150478342"
     variation       1053
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374385972"
     variation       1084
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:77972211"
     exon            1110..1279
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       1134
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146595043"
     variation       1166
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372759264"
     variation       1170
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200094211"
     variation       1186
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145134603"
     variation       1218
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201430480"
     variation       1230
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:61748696"
     variation       1269
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149010855"
     exon            1280..1369
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       1287
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:200021685"
     variation       1311
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:143010678"
     variation       1312
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375809703"
     variation       1317
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143478869"
     variation       1327
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200945319"
     variation       1350
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:75269203"
     variation       1368
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114901298"
     exon            1370..1542
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       1418
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:146045863"
     variation       1450
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144654966"
     variation       1453
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:267606996"
     variation       1470
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144231223"
     variation       1505
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146575990"
     variation       1509
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200543595"
     variation       1515
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142396337"
     variation       1539
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373494523"
     exon            1543..1597
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       1581
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:112562432"
     exon            1598..1966
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     STS             1636..1758
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /standard_name="RH25298"
                     /db_xref="UniSTS:70530"
     variation       1718
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140578891"
     variation       1724
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200175711"
     variation       1757
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370638150"
     variation       1762
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201394875"
     variation       1770
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368383124"
     variation       1777
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:137853053"
     variation       1786
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200166273"
     variation       1807
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370868041"
     variation       1822
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375582251"
     variation       1836
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:10445686"
     variation       1863
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:186856679"
     variation       1891
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368626850"
     variation       1911
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372715948"
     exon            1967..2104
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       2035
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:7595725"
     variation       2054
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:137853052"
     variation       2084
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:144534253"
     exon            2105..2332
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       2118
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375099600"
     variation       2157
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367558491"
     variation       2182
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376019553"
     variation       2265
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:150586651"
     variation       2272
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:369606881"
     variation       2308
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:17261772"
     variation       2322
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200499974"
     exon            2333..2429
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       2336
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141580332"
     variation       2372
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139996349"
     variation       2376
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146072589"
     variation       2389
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:370264179"
     exon            2430..2533
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       2462
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:148105837"
     variation       2480
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200907583"
     variation       2506
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:61748693"
     exon            2534..2649
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       2567
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371275629"
     variation       2582
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148557417"
     variation       2620
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200674508"
     variation       2642
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375414016"
     variation       2648
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145728829"
     exon            2650..2752
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       2660
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375263858"
     variation       2719
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:144455066"
     exon            2753..2773
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     exon            2774..4939
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /inference="alignment:Splign:1.39.8"
     variation       2785
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138004494"
     variation       2830
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113103875"
     variation       2832
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372552182"
     variation       2846
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376647431"
     variation       2854
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375847117"
     variation       2863
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369057346"
     variation       2864
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:77535003"
     variation       2901
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373166726"
     variation       2902
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138464557"
     variation       2907
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199983133"
     variation       2912
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200519153"
     variation       2968
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146045827"
     variation       3010
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141436429"
     variation       3019
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377383603"
     variation       3028
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202083403"
     variation       3044
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201884884"
     variation       3054
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369406767"
     variation       3145
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:10170125"
     variation       3174
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:80056711"
     variation       3180
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:180839370"
     variation       3181
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11558413"
     variation       3191
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371690596"
     variation       3211
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:78044288"
     variation       3262
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:7564565"
     variation       3265..3266
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:143703110"
     variation       3265
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:7564566"
     variation       3266..3267
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace=""
                     /replace="g"
                     /replace="ggg"
                     /db_xref="dbSNP:3214779"
     variation       3313
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:72980321"
     variation       3323
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:139040603"
     variation       3346
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:112136187"
     variation       3355
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375006650"
     variation       3358
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:189516775"
     variation       3359
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:111981151"
     variation       3414
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149483456"
     variation       3447
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181695291"
     variation       3517
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:186189305"
     variation       3641
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:190513478"
     variation       3751
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:149381237"
     STS             3763..3887
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /standard_name="SHGC-31260"
                     /db_xref="UniSTS:31772"
     variation       3849
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:372261698"
     variation       3947
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:71757791"
     variation       3974
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:181952710"
     variation       3988..3989
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:370069043"
     variation       4002
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11558414"
     variation       4005
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:116237324"
     STS             4055..4197
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /standard_name="D2S2871"
                     /db_xref="UniSTS:11276"
     variation       4087
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:16831395"
     variation       4136
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186292105"
     variation       4204
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:200869351"
     variation       4204
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:199592452"
     variation       4217..4218
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace=""
                     /replace="aa"
                     /db_xref="dbSNP:71899713"
     variation       4218..4220
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace=""
                     /replace="ata"
                     /db_xref="dbSNP:74490004"
     variation       4256
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191219662"
     variation       4264
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113651023"
     STS             4299..4483
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /standard_name="RH67847"
                     /db_xref="UniSTS:49267"
     variation       4388
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:59746814"
     variation       4407
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147177352"
     variation       4482
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:182541151"
     polyA_signal    4495..4500
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
     polyA_site      4517
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
     variation       4526..4534
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace=""
                     /replace="tttctttca"
                     /db_xref="dbSNP:200211652"
     variation       4597
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373223565"
     variation       4621
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:188370805"
     variation       4627
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140483004"
     STS             4649..4757
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /standard_name="A008U03"
                     /db_xref="UniSTS:82818"
     variation       4689
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369340827"
     variation       4703
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:144378327"
     STS             4783..4932
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /standard_name="WI-17012"
                     /db_xref="UniSTS:28796"
     variation       4836
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:114264557"
     variation       4845
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372998834"
     variation       4911
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377410397"
     polyA_signal    4917..4922
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
     variation       4930
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147828110"
     polyA_site      4939
                     /gene="RAB3GAP1"
                     /gene_synonym="P130; RAB3GAP; RAB3GAP130; WARBM1"
ORIGIN      
cttcttcccggcagccttagcgccaggcccggcgctcctcaagatggctgccgacagtgagcccgaatccgaggtatttgagatcacggacttcaccactgcctcggaatgggaaaggtttatttccaaagttgaagaagtcttgaatgactggaaactgattggaaactctttgggaaagccactcgaaaagggtatatttacttctggcacatgggaagagaaatcagatgaaatttcctttgctgacttcaagttctcagtcactcatcattatcttgtacaagagtccactgataaagaaggaaaggatgagttattagaggatgttgttccacaatctatgcaagatttgctgggtatgaataatgactttcctccaagagcacattgcctggtaagatggtatgggctacgtgagttcgtggtgattgcccctgctgcacacagtgacgctgttctcagcgaatctaagtgcaaccttcttctgagttctgtttctattgccttgggaaacactggctgtcaggtgccactctttgtgcaaattcaccacaaatggcgaagaatgtatgtaggagaatgtcaaggtcctggtgtacgaactgatttcgaaatggttcatcttagaaaagtgccaaatcagtacactcacttatcaggtctgctggatatcttcaaatcaaagattggatgtcctttaactccattgcctccagttagtattgctattcgatttacctatgtacttcaagattggcagcagtatttttggcctcagcaacctccagacatagatgcccttgtaggaggagaagttggaggcttggagtttggcaagttaccatttggtgcctgcgaagatcctattagtgaactccatttagctactacatggcctcatctgaccgaagggatcattgtggataatgatgtttattctgatttggatcctattcaagctccacattggtctgttagagttcgaaaagctgagaatcctcagtgtttgctaggtgattttgtcactgaattttttaaaatttgccgtcgaaaggagtcaactgatgagattcttggacgatctgcatttgaggaagaaggcaaagaaactgctgatataactcatgctttgtcaaaattgacagagccggcatcagttccaattcataaattatcagtttcaaatatggtacacactgcaaagaagaaaatccgaaaacacagaggtgtagaggagtcaccgctaaataatgatgttcttaatactattctcctgttcttattccctgatgctgtttctgagaaaccattagatggaactacttcaacagataataataatcctccatcagagagtgaagactataatctctacaatcagttcaagtctgcaccatctgacagtttaacatacaaactggctttgtgtctctgtatgatcaatttttaccatggagggttgaaaggagtggcacacctctggcaggaatttgttcttgaaatgcgtttccgatgggaaaacaactttctgattccaggattagcaagtggacccccagatctgaggtgttgtttactgcatcagaaactacagatgttaaattgttgtattgaaagaaagaaggcacgtgatgaggggaaaaagacaagtgcttcagatgtcactaatatatatccaggggatgctggaaaagcaggagaccagttggtgccagataatctaaaagaaacagataaggaaaagggagaggtaggaaaatcttgggattcctggagtgacagcgaagaagaattttttgaatgcctaagtgatactgaagaacttaaaggaaatggacaagagagtggcaagaaaggaggacctaaggagatggcaaatttaaggccggaaggacggctctatcagcatgggaaacttacactgctgcataatggagaacctctctacattccagtaacccaggaaccagcacctatgacagaagatctgctagaagagcagtctgaagttttagctaaattaggtacatcggcagagggggctcaccttcgagcacgcatgcagagtgcctgtctgctctcagatatggagtcttttaaggcagctaatccaggttgctccctggaagattttgtgaggtggtattcaccccgggattatattgaagaggaggtgattgatgaaaagggcaatgtggtgctgaaaggagaactgagtgcccggatgaagattccaagcaatatgtgggtagaagcctgggaaacagctaagccaattcctgctagaaggcaaaggagactctttgatgatacacgggaagcagaaaaggtgctgcactatctggcaatccagaaacctgcagaccttgctcggcacctgttaccttgtgtgattcatgcagctgtactcaaggtaaaggaagaagaaagtctcgaaaacatttcttcagttaagaagatcataaagcagataatatcccattccagtaaagttttgcacttccccaatccagaagacaagaaattggaagaaatcattcaccagattactaatgtggaagctctcattgccagagctcggtcactaaaagccaagtttggaactgagaaatgtgaacaggaggaggaaaaggaagatcttgaaaggtttgtgagttgcctgctggagcagcctgaagtgttagtcaccggtgcaggaagaggacatgctggcaggatcattcacaagctgtttgtgaatgcccagaggctgactgaatcttctgatgaggctgcagctatgactccaccagaggaggaattgaagagaatgggctccccagaggaaagaaggcagaactccgtgtcagacttcccaccccctgctggccgggaattcattttgcgcaccactgtgccgcgccctgctccctactccaaagctctgcctcagcggatgtacagtgttctcaccaaagaggactttagacttgcaggtgccttttcatcagatacttccttcttctgattcttctagcattactcgttggtggcttcagagacagtgctgcctcctcctgagggagggaaggtaccagggagaacctgggaggtcctggagagggccctgtccagttgggtgatcaggaatcaaaccagcatcggaaagacttcccagcaccaagcttgagctgtgtcgtttcgtggagggggcagcgaggatgggcttgagctgttgagagatttctgccctagagatggcctttgtatatgggggggtggtggggggacacaaacacatcagacactccgtcctcacactggcaggacggtgttcatcgcattctcttctgtgaccagcctctaggctagcggctgcattcgtggtctgtgcaaacacttcgtggttctatatatcagcagcaagtgtgcaaaataaaggacctgttaactcagatttctggatattttggtggtagcttctagtcccagaatctgtgtttttaaaatactacatgacattctgtctattcaatcacctggtggtcatctttcttgtactaattaactgttgatgagcattttggatattctaggagaaagcctataatttcacatagtttctctttttcatgtaactgtaacctaaatgtattacttctgataaaactatatatcaaatgtcactgcaaattagttttatatctgtcatgtgagatttgtcttacttatttttcttttggttgccatggaagttatggccctgaaaatcgtctccctccccttctcttgctgtacagcatgcgttctctttttgtggttgctggctgggtactgtatttaatgaagtagagaatagcacttgcaaaaatacagtcttggtacctagagactgtcatgcagatagtataatttggtatatgtgctaatgcattgagtagaggattattttaacacactattttgcttttgtattttagttaaaataatcgatggggatgtgtagcccccccgtgtgaggatgacatcaccacatttctagtttcatggagctcaagatgtcttgtgtctgtgtggctagatggcctctgcttggtaatcttatttttaggcctaaaattcccacttaaatccaaagtaaaaatggttatactgaagcataaaccttgcctgtgtaattttaaaaaattaatagagctgtgcaaaccctgttatttttgtaaaaaaaaaaaaaaatacatatctatatataatatgtgtgtgtgtgtgacatatgcacacgtctctgtgtatgtgaagtaggggaggccctgggggatgacctcccagcctttatgatgcttttctctatgctgctggacttcattcttactggtccacgcagatgcaggcggcctgaggccagtgctgtaccaagtagaagacggttcctaaggacagagtttgtctgttttctaacaaagaaaaattctacaaaggagaggttgggcgttacaaaggcattgtgaatctaataaaaggaaagtgtcgctttctgtggcgttttctttcattttctcccgctgaggcatttcagtctaatttcatgtggttttgtgctgtctcagctctaatgtttgcagcctgctgagcctaacaaggcagtggtctcaagaacattctttgtgcctttttaaagtactccattttatttttatgatagttatgtatttatttcacagatatatttaagtacccactttgtgtcaggtacagtacaagcaatgaagataaaacagaaaccaaaacacactcccttacagggaaaactgacaccacgttgccacaaaatgttgagtatagtcaactctgctgtgtggatcggagggcctgcatttatcctacaaataattgaatgtaatcctacattcatgtattcattggcagtacggagtaataaatgcagcaatgtcataaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:22930 -> Molecular function: GO:0005097 [Rab GTPase activator activity] evidence: IDA
            GeneID:22930 -> Molecular function: GO:0017137 [Rab GTPase binding] evidence: IPI
            GeneID:22930 -> Biological process: GO:0007420 [brain development] evidence: IMP
            GeneID:22930 -> Biological process: GO:0021854 [hypothalamus development] evidence: IMP
            GeneID:22930 -> Biological process: GO:0032851 [positive regulation of Rab GTPase activity] evidence: IDA
            GeneID:22930 -> Biological process: GO:0043010 [camera-type eye development] evidence: IMP
            GeneID:22930 -> Biological process: GO:0043087 [regulation of GTPase activity] evidence: IDA
            GeneID:22930 -> Biological process: GO:0060325 [face morphogenesis] evidence: IMP
            GeneID:22930 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:22930 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
            GeneID:22930 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:22930 -> Cellular component: GO:0005813 [centrosome] evidence: IDA

by @meso_cacase at DBCLS
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