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2024-04-26 01:44:38, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001171894 5771 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens myocyte enhancer factor 2A (MEF2A), transcript variant
5, mRNA.
ACCESSION NM_001171894
VERSION NM_001171894.1 GI:284807139
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5771)
AUTHORS Nitert,M.D., Dayeh,T., Volkov,P., Elgzyri,T., Hall,E., Nilsson,E.,
Yang,B.T., Lang,S., Parikh,H., Wessman,Y., Weishaupt,H., Attema,J.,
Abels,M., Wierup,N., Almgren,P., Jansson,P.A., Ronn,T., Hansson,O.,
Eriksson,K.F., Groop,L. and Ling,C.
TITLE Impact of an exercise intervention on DNA methylation in skeletal
muscle from first-degree relatives of patients with type 2 diabetes
JOURNAL Diabetes 61 (12), 3322-3332 (2012)
PUBMED 23028138
REMARK GeneRIF: DNA methylation of genes in retinol metabolism and calcium
signaling pathways (P < 3 x 10-6) and with known functions in
muscle and T2D including MEF2A, RUNX1, NDUFC2, and THADA decreased
after exercise
REFERENCE 2 (bases 1 to 5771)
AUTHORS Zhao,W., Zhao,S.P. and Peng,D.Q.
TITLE The effects of myocyte enhancer factor 2A gene on the
proliferation, migration and phenotype of vascular smooth muscle
cells
JOURNAL Cell Biochem. Funct. 30 (2), 108-113 (2012)
PUBMED 22028303
REMARK GeneRIF: MEF2A dominant negative mutation enhanced cell
proliferation and cell migration.
REFERENCE 3 (bases 1 to 5771)
AUTHORS Liu,Y., Niu,W., Wu,Z., Su,X., Chen,Q., Lu,L. and Jin,W.
TITLE Variants in exon 11 of MEF2A gene and coronary artery disease:
evidence from a case-control study, systematic review, and
meta-analysis
JOURNAL PLoS ONE 7 (2), E31406 (2012)
PUBMED 22363637
REMARK GeneRIF: The rare 21-bp deletion might have a more compelling
effect on coronary artery disease (CAD) than the common (CAG)(n)
polymorphism, and MEF2A genetic variant might be a rare but
specific cause of CAD/myocardial infarction.
Review article
REFERENCE 4 (bases 1 to 5771)
AUTHORS Katsarou,K., Tsitoura,P. and Georgopoulou,U.
TITLE MEK5/ERK5/mef2: a novel signaling pathway affected by hepatitis C
virus non-enveloped capsid-like particles
JOURNAL Biochim. Biophys. Acta 1813 (10), 1854-1862 (2011)
PUBMED 21767578
REMARK GeneRIF: HCVne particles are capable of inducing the recently
discovered ERK5 pathway, in a dose dependent way.
REFERENCE 5 (bases 1 to 5771)
AUTHORS She,H. and Mao,Z.
TITLE Regulation of myocyte enhancer factor-2 transcription factors by
neurotoxins
JOURNAL Neurotoxicology 32 (5), 563-566 (2011)
PUBMED 21741404
REMARK GeneRIF: [review] In this work, the mechanisms of regulation of
MEF2 function by several well-known neurotoxins and their
implications in various neurodegenerative diseases are reviewed.
Review article
REFERENCE 6 (bases 1 to 5771)
AUTHORS Molkentin,J.D., Black,B.L., Martin,J.F. and Olson,E.N.
TITLE Cooperative activation of muscle gene expression by MEF2 and
myogenic bHLH proteins
JOURNAL Cell 83 (7), 1125-1136 (1995)
PUBMED 8548800
REFERENCE 7 (bases 1 to 5771)
AUTHORS Hobson,G.M., Krahe,R., Garcia,E., Siciliano,M.J. and Funanage,V.L.
TITLE Regional chromosomal assignments for four members of the MADS
domain transcription enhancer factor 2 (MEF2) gene family to human
chromosomes 15q26, 19p12, 5q14, and 1q12-q23
JOURNAL Genomics 29 (3), 704-711 (1995)
PUBMED 8575763
REFERENCE 8 (bases 1 to 5771)
AUTHORS Funk,W.D. and Wright,W.E.
TITLE Cyclic amplification and selection of targets for multicomponent
complexes: myogenin interacts with factors recognizing binding
sites for basic helix-loop-helix, nuclear factor 1,
myocyte-specific enhancer-binding factor 2, and COMP1 factor
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 89 (20), 9484-9488 (1992)
PUBMED 1329097
REFERENCE 9 (bases 1 to 5771)
AUTHORS Yu,Y.T., Breitbart,R.E., Smoot,L.B., Lee,Y., Mahdavi,V. and
Nadal-Ginard,B.
TITLE Human myocyte-specific enhancer factor 2 comprises a group of
tissue-restricted MADS box transcription factors
JOURNAL Genes Dev. 6 (9), 1783-1798 (1992)
PUBMED 1516833
REFERENCE 10 (bases 1 to 5771)
AUTHORS Pollock,R. and Treisman,R.
TITLE Human SRF-related proteins: DNA-binding properties and potential
regulatory targets
JOURNAL Genes Dev. 5 (12A), 2327-2341 (1991)
PUBMED 1748287
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA778137.1, AB208985.1,
AC022692.11 and N93079.1.
Summary: The protein encoded by this gene is a DNA-binding
transcription factor that activates many muscle-specific, growth
factor-induced, and stress-induced genes. The encoded protein can
act as a homodimer or as a heterodimer and is involved in several
cellular processes, including muscle development, neuronal
differentiation, cell growth control, and apoptosis. Defects in
this gene could be a cause of autosomal dominant coronary artery
disease 1 with myocardial infarction (ADCAD1). Several transcript
variants encoding different isoforms have been found for this
gene.[provided by RefSeq, Jan 2010].
Transcript Variant: This variant (5) uses an alternate coding exon,
and contains an additional 5' non-coding exon, compared to
transcript variant 1. This results in a shorter isoform (2) with a
varied internal 43 aa segment compared to isoform 1. Variants 2 and
5 both encode isoform 2.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AB208985.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025081, ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-23 DA778137.1 1-23
24-1469 AB208985.1 1-1446
1470-1470 AC022692.11 146256-146256
1471-3092 AB208985.1 1448-3069
3093-5749 AC022692.11 153286-155942
5750-5771 N93079.1 1-22 c
FEATURES Location/Qualifiers
source 1..5771
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/map="15q26"
gene 1..5771
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/note="myocyte enhancer factor 2A"
/db_xref="GeneID:4205"
/db_xref="HGNC:6993"
/db_xref="MIM:600660"
exon 1..177
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
exon 178..259
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 225
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:115186154"
exon 260..467
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 273
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:187129021"
variation 301
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:111970264"
variation 302..303
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="g"
/db_xref="dbSNP:151012635"
STS 305..373
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/standard_name="D1S1423"
/db_xref="UniSTS:149619"
variation 376
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:370002348"
exon 468..663
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
misc_feature 601..603
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/note="upstream in-frame stop codon"
CDS 610..2103
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/note="isoform 2 is encoded by transcript variant 5; MADS
box transcription enhancer factor 2, polypeptide A
(myocyte enhancer factor 2A); myocyte-specific enhancer
factor 2A; serum response factor-like protein 1"
/codon_start=1
/product="myocyte-specific enhancer factor 2A isoform 2"
/protein_id="NP_001165365.1"
/db_xref="GI:284807140"
/db_xref="CCDS:CCDS53978.1"
/db_xref="GeneID:4205"
/db_xref="HGNC:6993"
/db_xref="MIM:600660"
/translation="
MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNEDSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTEDRESPSVKRMRMDAWVT
"
misc_feature 613..843
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/note="MEF2 (myocyte enhancer factor 2)-like/Type II
subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF
(serum response factor) box family of eukaryotic
transcriptional regulators. Binds DNA and exists as hetero
and homo-dimers. Differs from SRF-like/Type I...; Region:
MADS_MEF2_like; cd00265"
/db_xref="CDD:29020"
misc_feature order(613..621,625..627,631..633,646..648,652..654,
664..669,676..681,685..690,697..702,706..711,721..723)
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:29020"
misc_feature order(670..672,691..696,703..708,712..717,724..726,
739..741,745..747,751..753,769..771,775..777,793..795,
802..807,814..816,823..828)
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/note="dimerization interface [polypeptide binding]; other
site"
/db_xref="CDD:29020"
misc_feature 784..786
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/note="putative phosphorylation site [posttranslational
modification]; other site"
/db_xref="CDD:29020"
misc_feature 892..1068
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/note="Holliday junction regulator protein family
C-terminal repeat; Region: HJURP_C; pfam12347"
/db_xref="CDD:152782"
STS 619..1030
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/standard_name="Mef2a"
/db_xref="UniSTS:265600"
STS 619..979
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/standard_name="Mef2a"
/db_xref="UniSTS:265601"
variation 633
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:370523988"
exon 664..867
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 723
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:191032083"
variation 751
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:368747387"
variation 774
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:372436031"
variation 777
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:200687749"
exon 868..999
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 868
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:17423081"
variation 875
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:3205682"
variation 890
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:368757733"
variation 891
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:1135555"
variation 897
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:1135556"
variation 900
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:1135557"
variation 906
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:1135558"
variation 909
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:1135559"
variation 910
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:1135560"
variation 915
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:1135561"
variation 922
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:1135562"
variation 926
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:3208173"
variation 932
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:1135563"
variation 939
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:1136937"
variation 942
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:3198317"
variation 945
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:1135564"
variation 948
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:1135565"
variation 954
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:1135566"
variation 956
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:1135567"
variation 957
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:1135568"
variation 961
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:1135569"
variation 969
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:1135570"
variation 974
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:1135571"
variation 979
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:1135572"
variation 980
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:1135574"
variation 995
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:1135575"
variation 999
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:17420057"
exon 1000..1219
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 1070
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:374058145"
variation 1120
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:189538320"
variation 1122
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:3803420"
variation 1155
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:146192119"
variation 1166
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:370083199"
variation 1201
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:373867888"
exon 1220..1279
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 1232
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:199820037"
variation 1248
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:376779827"
variation 1261
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:377207410"
exon 1280..1467
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 1346
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:189526729"
variation 1360
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:199751824"
variation 1365
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:369943942"
variation 1391
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:121918530"
variation 1399
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:79454361"
variation 1410
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:200748600"
variation 1437
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:369552532"
variation 1438
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:373219260"
variation 1439
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:121918529"
variation 1451
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:121918531"
variation 1464
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:376183174"
exon 1468..1594
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 1470..1471
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:17854846"
variation 1470
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:325408"
variation 1476
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:325407"
variation 1515
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:3730283"
variation 1551
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:372479689"
variation 1573
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:373204094"
exon 1595..1721
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 1608
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:373943430"
variation 1611
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:368107439"
variation 1612
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:373128826"
exon 1722..5757
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 1722
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:199613639"
variation 1751
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:375108417"
variation 1764
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:369483642"
STS 1781..1938
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/standard_name="G64293"
/db_xref="UniSTS:158672"
variation 1817
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:372533601"
variation 1827
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:144461661"
variation 1829
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:369579124"
variation 1830
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:3730059"
variation 1836..1837
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="cagcag"
/db_xref="dbSNP:374033278"
variation 1837..1842
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="cagcag"
/db_xref="dbSNP:3138597"
variation 1837..1839
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="cag"
/db_xref="dbSNP:373652230"
variation 1841..1846
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="agcagc"
/db_xref="dbSNP:58424802"
variation 1845..1850
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="gcagca"
/db_xref="dbSNP:72276751"
variation 1846..1847
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="cagcag"
/db_xref="dbSNP:72236998"
variation 1847..1848
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="agcagc"
/db_xref="dbSNP:72416294"
variation 1853
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:200861006"
variation 1856..1861
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="agcagc"
/db_xref="dbSNP:72198683"
variation 1865
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:201861701"
variation 1868
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:199811207"
variation 1874
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:369815961"
variation 1884
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:367780642"
variation 1932
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:325400"
variation 1948
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:370921147"
variation 2019
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:34851361"
variation 2020
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:111748677"
variation 2033
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:370778860"
variation 2248..2249
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="gtgt"
/db_xref="dbSNP:145618675"
variation 2248
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:201277440"
variation 2249..2250
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="gtgt"
/db_xref="dbSNP:144020290"
variation 2250..2251
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="gtgt"
/db_xref="dbSNP:10628004"
variation 2255..2256
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="gtgt"
/db_xref="dbSNP:34507751"
variation 2255
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:28444186"
variation 2295
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:374107493"
variation 2342
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:376220587"
variation 2606
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:75665175"
variation 2617
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:140014502"
variation 2629
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:72760574"
variation 2671
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:190007997"
variation 2678
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:201784078"
variation 2678
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="g"
/db_xref="dbSNP:34756453"
variation 2743
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:145205421"
variation 2755
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:11635271"
STS 2758..3107
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/standard_name="D15S907"
/db_xref="UniSTS:279"
variation 2968
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:182261693"
variation 3119
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:1059750"
variation 3120
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:186608671"
variation 3145
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:1454315"
variation 3295
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:190999757"
variation 3525..3529
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="gttaa"
/db_xref="dbSNP:71982844"
variation 3532
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="aactt"
/db_xref="dbSNP:67611863"
variation 3535
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:1059755"
variation 3536
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:149125295"
variation 3540
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:1059756"
variation 3546
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:1059757"
variation 3570..3571
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:1059758"
variation 3571
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:325399"
variation 3576
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:1136940"
variation 3761
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:142460833"
variation 3762
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:184041593"
variation 3787
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:368872347"
variation 3852
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:897074"
variation 4080
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:188542083"
variation 4099
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:372386338"
variation 4131
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:375267826"
variation 4138
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:59420387"
variation 4140
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:12902459"
variation 4141..4142
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="a"
/db_xref="dbSNP:67644135"
variation 4142
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="c"
/db_xref="dbSNP:58267790"
variation 4144..4145
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="cc"
/db_xref="dbSNP:141367967"
variation 4144
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="c"
/db_xref="dbSNP:144314500"
variation 4146
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:11550216"
variation 4147
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:75869168"
variation 4148
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:148429386"
variation 4153
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="c"
/replace="cc"
/db_xref="dbSNP:58849948"
variation 4161
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:1059759"
variation 4173
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:325383"
variation 4231
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:325382"
variation 4299
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:1059760"
variation 4312
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:11550217"
variation 4317
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:193162969"
variation 4336
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:184981047"
variation 4339
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:187250165"
variation 4422
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:372383636"
variation 4479
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:146891523"
variation 4669
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:191660882"
variation 4778
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:41303617"
variation 4859
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:140716704"
variation 4941
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:325381"
variation 4942
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="g"
/db_xref="dbSNP:200152842"
variation 4960
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:183911417"
variation 5038
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:113970475"
variation 5066
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:188188955"
variation 5071
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="a"
/db_xref="dbSNP:34602555"
variation 5150
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:182321371"
variation 5152
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:113827147"
variation 5192
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:145829205"
variation 5199..5200
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="cat"
/db_xref="dbSNP:374735275"
variation 5199
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:77710130"
variation 5200..5201
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="atc"
/db_xref="dbSNP:371572866"
variation 5219
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:28377673"
variation 5233
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:138403437"
variation 5344
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:74033759"
STS 5482..5754
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/standard_name="D15S901"
/db_xref="UniSTS:13157"
variation 5605
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:150316263"
variation 5667
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:12442844"
polyA_site 5685
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
polyA_signal 5709..5714
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
polyA_site 5738
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
variation 5745
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:325380"
polyA_site 5757
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
ORIGIN
agaacgagttccggtctggccgaggcttgtctcctaaaaatagccccggtgtggggatccgtgcgcggatgtcccggcgagtcccgggctgaaagaggcggctccgggcggcgcgaagcgctggtggcgggcccgggctgcggcgtgtgcgcgcccgccagctgctccggagatacggaattgcattttgtgaaaaaagaacaagaattttctgcaaggatcatatctaagtgcactttttgctgatacttcatttctatctcactctaccccccaggctgaagtgcagtggtgtgatctcggttcactgcaacctccgcctccaggttcaagtgattctcgtacctcagcctcccgagtagctgggattacaggcgcctgccaccatgcctggctgatatttatatttttagtagagatggagtttcaccatgttggccaggctggtctcgaactctggacctcagatcttgtagaaaatttcagctgtagcccttggactagaagctgaaataacagaagctgtgtacgatgcattagggtattgaagaaaattaacttttgaattaaatatttggaatataaggaaataaggaaagttgactgaaaatggggcggaagaaaatacaaatcacacgcataatggatgaaaggaaccgacaggtcacttttacaaagagaaagtttggattaatgaagaaagcctatgaacttagtgtgctctgtgactgtgaaatagcactcatcattttcaacagctctaacaaactgtttcaatatgctagcactgatatggacaaagttcttctcaagtatacagaatataatgaacctcatgaaagcagaaccaactcggatattgttgagactttaagaaagaaaggccttaatggttgtgagagccctgatgctgacgattactttgagcacagtccactctcggaggacagattcagcaaactaaatgaagatagtgattttattttcaaacgaggccctcctggtctgccacctcagaacttttcaatgtctgtcacagttccagtgaccagccccaatgctttgtcctacactaacccagggagttcactggtgtccccatctttggcagccagctcaacgttaacagattcaagcatgctctctccacctcaaaccacattacatagaaatgtgtctcctggagctcctcagagaccaccaagtactggcaatgcaggtgggatgttgagcactacagacctcacagtgccaaatggagctggaagcagtccagtggggaatggatttgtaaactcaagagcttctccaaatttgattggagctactggtgcaaatagcttaggcaaagtcatgcctacaaagtctccccctccaccaggtggtggtaatcttggaatgaacagtaggaaaccagatcttcgagttgtcatccccccttcaagcaagggcatgatgcctccactaaatacccaaaggatcagtagttctcaagccactcaacctcttgctaccccagtcgtgtctgtgacaaccccaagcttgcctccgcaaggacttgtgtactcagcaatgccgactgcctacaacactgattattcactgaccagcgctgacctgtcagcccttcaaggcttcaactcgccaggaatgctgtcgctgggacaggtgtcggcctggcagcagcaccacctaggacaagcagccctcagctctcttgttgctggagggcagttatctcagggttccaatttatccattaataccaaccaaaacatcagcatcaagtccgaaccgatttcacctcctcgggatcgtatgaccccatcgggcttccagcagcagcagcagcagcagcagcagcagcagccgccgccaccaccgcagccccagccacaacccccgcagccccagccccgacaggaaatggggcgctcccctgtggacagtctgagcagctctagtagctcctatgatggcagtgatcgggaggatccacggggcgacttccattctccaattgtgcttggccgacccccaaacactgaggacagagaaagcccttctgtaaagcgaatgaggatggacgcgtgggtgacctaaggcttccaagctgatgtttgtacttttgtgttactgcagtgacctgccctacatatctaaatcggtaaataaggacatgagttaaatatatttatatgtacatacatatatatatccctttacatatatatgtatgtgggtgtgagtgtgtatgtgtgggtgtgtgttacatacacagaatcaggcacttacctgcaaactccttgtaggtctgcagatgtgtgtcccatggcagacaaagcaccctgtaggcacagacaagtctggcacttccttggactacttgtttcgtaaagataaccagtttttgcagagaaacgtgtacccatatataattctcccacactagcttgcagaaacctagagggccccctacttgttttatttaactgtgcagtgactgtagttacttaagagaaaatgctttgtagaacagagcagtagaaaagcaggaaccaagaaagcaatactgtacataaaatgtcatttatattttccaacctggcatgggtgtctgttgcaaaggggtgcatgggaaagggctgttgatattaaaaacaaacaaaacaaaaaagccccacacataactgttttgcacgtgcaaaaatgtattgggtcaagaagtgatctttagctaataaagaaagagaatagaaaacacgcatgagatattcagaaaatactagcctagaaatatagagcattaacaaagtaaaattaatatattaagttataattggaatatgtcagaagtttctttttacattcatatcttaaaaattaaagaaactgattttagctcatgtatattttatatgaaagaaaacacccttatgaattgatgactatatataaaattatattcactacttttgaacacattctgctatgaattatttatataagccaaagctatatgttgtaacttttttttagagaatagctttatcttggtttaactctttagttttattttaagaggggaaaacaaaaatatcttgcaagcagaaccttggaaaaaaaaagccatgaacacttattctaaatgtaaattaaaagttgagccaaactctttgtgtatatagcatcttaaatatattatcacctttgatgtaagtacctatgtattgtatggtcaccagattaaaaagtatatttttgtggattgccgccaatctggggggaaaaggcgaggtcctttattaagtattcactgtttaatatttactattttgttaaatatactgtactttggattttaattattagcccagttttttcagaggattgtataaaggggtttctcccctcactggtggtgaatgtgtgatgttacattgtaatctttgtgctgtatgggttgagcatcattatatattttgtatgtgtacataaatagcaaagtggcaaaaaaaattggtgttaagttcatcctgcataagtataaaatgtgttgtaacagattttgtaaggcattatttaaaacttgccttttgtgaggaaaaaatgtagtagaaaaagctgacctaatttaattaatattagagaaaatggcaaaatagtagatgagcacaaaggttttataagtggtaaatgattaggggaaaataatcatggggaaagggatcttttttccttgaccctctgaaaacagaacgatgcagctggttacaaaatcctaccgttatcagctcttctgcacattgcagtgatgctttggtatgcggggagaaacactcttagggtgctggtccttggcatgactcttgccattctaattggaattagtgccaccctcagcttggattttgaacaaggccttattctttcaggaagacaactaatggatgatagcaagttcatccacttactgggcttgtgccatgagcaaaattcaaagtcctgtatatctttcattgtagatttttaaatactccttttcctaaaaaactcaagggtttaaaaattgctattttatattttaaatgatattgagcagctacctacaatttctatgtacattttgttcccccccccccaccccccccccaaattacgttccttttgacattttcctcatctgctgtttgtgacaagtcatcagccagatttcctgactgacacataggtatgatcagtgcaggagagacctgcgcaccacaggctgcaaactggaggttctgttctcatggcagtttgggcagtaacttttgagagaggccaaaaaaaggaggatgacatgctgtctcctctcttcagtatagacattaggctcttattcagaaaggatttttctttaaaaatgtacttactttactgaactacttacaggcacatttcttcataaggccacacctaatccaaacaagacagtctcccaacactgaagttccaaaataatccttaccactttgtaaaccatttatagctttgaaagtgttaagtgattccttcgttattatttatgcatgttcatgaacttctgctgtacattggaataggagttaacacattcacatttactgtctattttcttgtgtgccttatgagatggcttttctgactgtatctcaatagtctttctttctatgcaggtttataatcagtacaactactgttttctaaaatactactactcaaggctcggagtttgtatttaaattacactgaccaagtaacaatgtattccatttcaggaactgaatatttgactgttaacctttttcccatacgtccagtgtggcatggagcatatggacttgacagacatctctcacccagacgcccacgtgtgaacacacccacatccacatctctgggtggaaaccagcctagagaggggacgacgctaatggtgttgctttagaaccgtcttttcttacccttttagactcgtgttttgtatgagacaccattgcaagaaaattttatccctccagaagtattttattactaaagaacaaaagcaaaaaaagcttaaattgcactggttaaagtacagtttccaacagctgtccttcctcagtactctaatggccactccaccgcgagtggaagtcactgttgtgtgtacacaggtggtcccaatcaaaactccatcttttgagcccaattatgtccattttgttatagactaaatcaggggtttgttctacaagaacaatacatgttttaccctttcctttaactagaaggataactagtaatgcatcaacataatttctgtattaaccatcatgcgcacaagaaatacatagtaaataaggaagctgaaaactcctggcattggatcttaagctagatgattagaatgtgaaaaagattttacaaatgtaaaacttctatttctctgtagaaactttcttcactttgctgtgcaagaagacactgctttgctatatttaaaatggcttttttaaaagagatttatgtatttggtaaatgtttgtagtcaacagttcacacaagaagctgtacacggtttgatcatgtaaaaccgtttggcggcacaagctggactttgttgccatccttgagatgaaccttttaagaaaaataagttaatctcaatttttccctgaatgtgttgtttttcttcattatacaataaatataatagtgaactttttatcaaatggtgaagacaatgctaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:4205 -> Molecular function: GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] evidence: IDA
GeneID:4205 -> Molecular function: GO:0000981 [sequence-specific DNA binding RNA polymerase II transcription factor activity] evidence: IDA
GeneID:4205 -> Molecular function: GO:0001077 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription] evidence: IEA
GeneID:4205 -> Molecular function: GO:0001085 [RNA polymerase II transcription factor binding] evidence: IPI
GeneID:4205 -> Molecular function: GO:0001105 [RNA polymerase II transcription coactivator activity] evidence: IDA
GeneID:4205 -> Molecular function: GO:0003682 [chromatin binding] evidence: IDA
GeneID:4205 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IDA
GeneID:4205 -> Molecular function: GO:0003705 [RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity] evidence: IEA
GeneID:4205 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:4205 -> Molecular function: GO:0019901 [protein kinase binding] evidence: IEA
GeneID:4205 -> Molecular function: GO:0033613 [activating transcription factor binding] evidence: IPI
GeneID:4205 -> Molecular function: GO:0035035 [histone acetyltransferase binding] evidence: IPI
GeneID:4205 -> Molecular function: GO:0042826 [histone deacetylase binding] evidence: IPI
GeneID:4205 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IDA
GeneID:4205 -> Molecular function: GO:0046332 [SMAD binding] evidence: IPI
GeneID:4205 -> Molecular function: GO:0046982 [protein heterodimerization activity] evidence: IPI
GeneID:4205 -> Biological process: GO:0000002 [mitochondrial genome maintenance] evidence: ISS
GeneID:4205 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:4205 -> Biological process: GO:0000165 [MAPK cascade] evidence: IDA
GeneID:4205 -> Biological process: GO:0002224 [toll-like receptor signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0002756 [MyD88-independent toll-like receptor signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IDA
GeneID:4205 -> Biological process: GO:0006366 [transcription from RNA polymerase II promoter] evidence: IDA
GeneID:4205 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:4205 -> Biological process: GO:0007507 [heart development] evidence: IEP
GeneID:4205 -> Biological process: GO:0007517 [muscle organ development] evidence: NAS
GeneID:4205 -> Biological process: GO:0034134 [toll-like receptor 2 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0034138 [toll-like receptor 3 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0034142 [toll-like receptor 4 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0034146 [toll-like receptor 5 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0034162 [toll-like receptor 9 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0034166 [toll-like receptor 10 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0035666 [TRIF-dependent toll-like receptor signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0042692 [muscle cell differentiation] evidence: TAS
GeneID:4205 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
GeneID:4205 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:4205 -> Biological process: GO:0048011 [neurotrophin TRK receptor signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0048311 [mitochondrion distribution] evidence: ISS
GeneID:4205 -> Biological process: GO:0048813 [dendrite morphogenesis] evidence: ISS
GeneID:4205 -> Biological process: GO:0051149 [positive regulation of muscle cell differentiation] evidence: TAS
GeneID:4205 -> Biological process: GO:0051403 [stress-activated MAPK cascade] evidence: TAS
GeneID:4205 -> Biological process: GO:0055005 [ventricular cardiac myofibril assembly] evidence: ISS
GeneID:4205 -> Biological process: GO:0061337 [cardiac conduction] evidence: ISS
GeneID:4205 -> Biological process: GO:0070375 [ERK5 cascade] evidence: IMP
GeneID:4205 -> Biological process: GO:0071277 [cellular response to calcium ion] evidence: IDA
GeneID:4205 -> Cellular component: GO:0000790 [nuclear chromatin] evidence: ISS
GeneID:4205 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:4205 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
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@meso_cacase at
DBCLS
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