2024-04-20 03:33:50, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001168298 2672 bp mRNA linear PRI 07-JUL-2013 DEFINITION Homo sapiens chemokine (C-X-C motif) receptor 2 (CXCR2), transcript variant 2, mRNA. ACCESSION NM_001168298 VERSION NM_001168298.1 GI:269973858 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 2672) AUTHORS Zeng,Z., Shaffer,J.R., Wang,X., Feingold,E., Weeks,D.E., Lee,M., Cuenco,K.T., Wendell,S.K., Weyant,R.J., Crout,R., McNeil,D.W. and Marazita,M.L. TITLE Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition JOURNAL J. Dent. Res. 92 (5), 432-437 (2013) PUBMED 23470693 REFERENCE 2 (bases 1 to 2672) AUTHORS Ravindran,A., Sawant,K.V., Sarmiento,J., Navarro,J. and Rajarathnam,K. TITLE Chemokine CXCL1 dimer is a potent agonist for the CXCR2 receptor JOURNAL J. Biol. Chem. 288 (17), 12244-12252 (2013) PUBMED 23479735 REMARK GeneRIF: Chemokine CXCL1 dimer is a potent agonist for the CXCR2 receptor. REFERENCE 3 (bases 1 to 2672) AUTHORS Saintigny,P., Massarelli,E., Lin,S., Ahn,Y.H., Chen,Y., Goswami,S., Erez,B., O'Reilly,M.S., Liu,D., Lee,J.J., Zhang,L., Ping,Y., Behrens,C., Solis Soto,L.M., Heymach,J.V., Kim,E.S., Herbst,R.S., Lippman,S.M., Wistuba,I.I., Hong,W.K., Kurie,J.M. and Koo,J.S. TITLE CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma JOURNAL Cancer Res. 73 (2), 571-582 (2013) PUBMED 23204236 REMARK GeneRIF: CXCR2 axis gene expression profiles in human NSCLC cell lines and lung adenocarcinomas defined a cluster driven by CXCL5 and associated with smoking, poor prognosis, and RAS pathway activation. REFERENCE 4 (bases 1 to 2672) AUTHORS Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A, Boucher G, Brand S, Buning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH, Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK, Zhao H, Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ, Franke A, Parkes M, Vermeire S, Barrett JC and Cho JH. CONSRTM International IBD Genetics Consortium (IIBDGC) TITLE Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease JOURNAL Nature 491 (7422), 119-124 (2012) PUBMED 23128233 REFERENCE 5 (bases 1 to 2672) AUTHORS Dwyer,J., Hebda,J.K., Le Guelte,A., Galan-Moya,E.M., Smith,S.S., Azzi,S., Bidere,N. and Gavard,J. TITLE Glioblastoma cell-secreted interleukin-8 induces brain endothelial cell permeability via CXCR2 JOURNAL PLoS ONE 7 (9), E45562 (2012) PUBMED 23029099 REMARK GeneRIF: Glioblastoma cell-secreted interleukin-8 induces brain endothelial cell permeability via CXCR2. REFERENCE 6 (bases 1 to 2672) AUTHORS Morris,S.W., Nelson,N., Valentine,M.B., Shapiro,D.N., Look,A.T., Kozlosky,C.J., Beckmann,M.P. and Cerretti,D.P. TITLE Assignment of the genes encoding human interleukin-8 receptor types 1 and 2 and an interleukin-8 receptor pseudogene to chromosome 2q35 JOURNAL Genomics 14 (3), 685-691 (1992) PUBMED 1427896 REFERENCE 7 (bases 1 to 2672) AUTHORS Lee,J., Horuk,R., Rice,G.C., Bennett,G.L., Camerato,T. and Wood,W.I. TITLE Characterization of two high affinity human interleukin-8 receptors JOURNAL J. Biol. Chem. 267 (23), 16283-16287 (1992) PUBMED 1379593 REFERENCE 8 (bases 1 to 2672) AUTHORS Murphy,P.M. and Tiffany,H.L. TITLE Cloning of complementary DNA encoding a functional human interleukin-8 receptor JOURNAL Science 253 (5025), 1280-1283 (1991) PUBMED 1891716 REFERENCE 9 (bases 1 to 2672) AUTHORS Holmes,W.E., Lee,J., Kuang,W.J., Rice,G.C. and Wood,W.I. TITLE Structure and functional expression of a human interleukin-8 receptor JOURNAL Science 253 (5025), 1278-1280 (1991) PUBMED 1840701 REFERENCE 10 (bases 1 to 2672) AUTHORS Itoh,H., Toyama,R., Kozasa,T., Tsukamoto,T., Matsuoka,M. and Kaziro,Y. TITLE Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs JOURNAL J. Biol. Chem. 263 (14), 6656-6664 (1988) PUBMED 2834384 COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA674925.1, AC124768.4 and AJ710879.1. Summary: The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009]. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA674925.1, CN836893.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-580 DA674925.1 1-580 581-2526 AC124768.4 70772-72717 2527-2672 AJ710879.1 1-146 FEATURES Location/Qualifiers source 1..2672 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="2" /map="2q35" gene 1..2672 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /note="chemokine (C-X-C motif) receptor 2" /db_xref="GeneID:3579" /db_xref="HGNC:6027" /db_xref="MIM:146928" exon 1..70 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /inference="alignment:Splign:1.39.8" exon 71..133 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /inference="alignment:Splign:1.39.8" misc_feature 91..93 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /note="upstream in-frame stop codon" variation 97 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:201034122" variation 104 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201979333" exon 134..185 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /inference="alignment:Splign:1.39.8" variation 148 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="g" /replace="t" /db_xref="dbSNP:201877059" variation 150 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="g" /replace="t" /db_xref="dbSNP:200242599" variation 152 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /db_xref="dbSNP:201386473" variation 158 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="t" /db_xref="dbSNP:199650637" variation 179 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200485079" exon 186..2662 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /inference="alignment:Splign:1.39.8" variation 199 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="g" /replace="t" /db_xref="dbSNP:55781915" variation 204 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201205999" CDS 211..1293 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /note="interleukin 8 receptor, beta; interleukin 8 receptor B; CXCR2 gene for IL8 receptor type B; interleukin 8 receptor type 2; chemokine (CXC) receptor 2; high affinity interleukin-8 receptor B; GRO/MGSA receptor; interleukin-8 receptor type B; CXC-R2; CXCR-2; IL-8R B; IL-8 receptor type 2" /codon_start=1 /product="C-X-C chemokine receptor type 2" /protein_id="NP_001161770.1" /db_xref="GI:269973859" /db_xref="CCDS:CCDS2408.1" /db_xref="GeneID:3579" /db_xref="HGNC:6027" /db_xref="MIM:146928" /translation="
MEDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL
" misc_feature 355..435 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P25025.2); transmembrane region" misc_feature 427..1152 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /note="7 transmembrane receptor (rhodopsin family); Region: 7tm_1; pfam00001" /db_xref="CDD:200918" misc_feature 463..525 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P25025.2); transmembrane region" misc_feature 571..636 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P25025.2); transmembrane region" misc_feature 700..759 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P25025.2); transmembrane region" misc_feature 835..903 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P25025.2); transmembrane region" misc_feature 964..1029 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P25025.2); transmembrane region" misc_feature 1093..1155 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /inference="non-experimental evidence, no additional details recorded" /note="propagated from UniProtKB/Swiss-Prot (P25025.2); transmembrane region" variation 227 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="g" /replace="t" /db_xref="dbSNP:139809702" variation 228 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201134932" variation 240 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:369575199" variation 247 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /db_xref="dbSNP:371161134" variation 253 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:55672388" variation 272 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:199905091" variation 285 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200836817" variation 297 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="g" /replace="t" /db_xref="dbSNP:148935180" variation 300 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /replace="t" /db_xref="dbSNP:142762038" variation 311 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:191559601" STS 317..743 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /standard_name="PMC135988P2" /db_xref="UniSTS:270788" variation 318 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201373363" variation 319 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:75759064" variation 329 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:200402782" variation 345 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="t" /db_xref="dbSNP:183812193" variation 346 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:55678589" variation 351 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:141285974" variation 374 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="t" /db_xref="dbSNP:199770538" variation 391 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:11574748" variation 414 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /replace="t" /db_xref="dbSNP:201294973" variation 415 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:368269858" variation 433 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:199633255" variation 444 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:150483744" variation 445 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:149364972" variation 448 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:138773569" variation 453 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:372364370" variation 454 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201754155" STS 460..905 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /standard_name="PMC310709P2" /db_xref="UniSTS:272638" variation 480 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:200819332" variation 482 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:199535002" variation 484 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:142747099" variation 523 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201513058" STS 529..1164 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /standard_name="PMC155779P2" /db_xref="UniSTS:271353" STS 529..778 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /standard_name="PMC155779P3" /db_xref="UniSTS:271354" variation 529 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="t" /db_xref="dbSNP:200115845" variation 558 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:147368052" variation 576 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:201382541" variation 606 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:199919394" variation 618 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:376503094" variation 619 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:369839517" variation 640 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:141722043" variation 643 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201114751" STS 666..1188 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /standard_name="IL8R-1" /db_xref="UniSTS:251622" variation 666 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:375690914" variation 668 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:55799208" variation 681 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:146545386" variation 685 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200940650" variation 686 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:368809767" variation 692 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="g" /replace="t" /db_xref="dbSNP:202076117" variation 711 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200386344" variation 736 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:199906283" variation 738 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="g" /replace="t" /db_xref="dbSNP:201535541" variation 741 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:201960181" variation 760 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200409575" variation 768 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201476763" variation 769 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:199777583" variation 794 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:200413041" variation 804 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201063764" variation 805 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201694058" variation 813 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:199692849" variation 826 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:200627519" variation 840 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:143703189" variation 852 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="g" /replace="t" /db_xref="dbSNP:202054642" variation 860 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:199822657" variation 861 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200776607" variation 873 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:141723765" variation 879 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:2228414" variation 887 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:141096894" variation 897 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201979852" variation 903 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:138670528" variation 904 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201103729" variation 916 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:10201766" variation 917 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:144013681" variation 921 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201499279" variation 931 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:61733608" variation 943 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:200332183" variation 953 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:61733609" variation 961 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:373547007" variation 962 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:199561988" variation 966 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:17844699" STS 975..1164 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /standard_name="PMC155779P1" /db_xref="UniSTS:271352" variation 978 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:11574750" variation 996 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:2230054" variation 1059 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:200911312" variation 1064 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /replace="g" /db_xref="dbSNP:201881186" variation 1069 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="g" /replace="t" /db_xref="dbSNP:201264119" variation 1073 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:199642674" variation 1075 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200726461" variation 1076 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:186640530" variation 1086 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:199873547" variation 1087..1088 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="" /replace="g" /db_xref="dbSNP:34747313" variation 1090 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:141145934" variation 1091 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:2228413" variation 1094 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200127100" variation 1107 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:13306439" variation 1120 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:373633146" variation 1123 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201271219" variation 1144..1145 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="" /replace="c" /db_xref="dbSNP:36094489" variation 1146 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:45606837" variation 1152 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:143174409" variation 1153 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:200906463" variation 1175 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201872950" variation 1178 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:200182920" variation 1201 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201481173" variation 1205 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:199632317" variation 1206 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:17844701" variation 1227 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201578768" variation 1232 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:199534482" variation 1244 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /db_xref="dbSNP:146279580" variation 1246 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /db_xref="dbSNP:200600788" variation 1247 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201772068" variation 1248 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:141985893" variation 1251 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /replace="g" /replace="t" /db_xref="dbSNP:11574751" variation 1253 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:370921619" variation 1256 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="t" /db_xref="dbSNP:200917361" STS 1269..1468 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /standard_name="RH69171" /db_xref="UniSTS:15270" variation 1269 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201890292" variation 1285 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="t" /db_xref="dbSNP:150629039" variation 1288 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /db_xref="dbSNP:373447323" variation 1290 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:201280885" variation 1292 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201597594" STS 1297..1499 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /standard_name="STS-L19593" /db_xref="UniSTS:37178" variation 1299 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:370198012" variation 1308 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /db_xref="dbSNP:199886410" variation 1317 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:200811589" variation 1318 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:200375313" variation 1323 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:200327176" variation 1330 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200366084" variation 1340 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:374087831" STS 1346..1562 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /standard_name="SHGC-35278" /db_xref="UniSTS:8485" variation 1362 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:202145285" variation 1366 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:191445302" variation 1389 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201610228" variation 1407 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:202138860" variation 1420 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:1126579" variation 1429 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201301122" variation 1444 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:199662489" variation 1449 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200910303" variation 1463 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201580582" variation 1477 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:199529314" variation 1481 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="g" /replace="t" /db_xref="dbSNP:184907766" variation 1487 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200661535" variation 1493 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201497688" variation 1501 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200083985" variation 1528 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="" /replace="c" /db_xref="dbSNP:375176823" variation 1538 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:200713198" variation 1589 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201358180" variation 1592 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /db_xref="dbSNP:199960281" variation 1615 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201255939" variation 1624 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:202122610" variation 1631 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:13306441" variation 1640 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200944263" variation 1644 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /db_xref="dbSNP:202081724" variation 1648 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:17844765" variation 1652 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:1126580" variation 1660 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="" /replace="c" /db_xref="dbSNP:56176202" variation 1666 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /db_xref="dbSNP:144937879" variation 1676 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="t" /db_xref="dbSNP:201975844" variation 1678 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:200358732" variation 1679..1680 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="" /replace="a" /db_xref="dbSNP:11384701" variation 1693 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="t" /db_xref="dbSNP:201616246" variation 1694 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="t" /db_xref="dbSNP:199720972" variation 1700 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:56153350" variation 1701 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201060551" variation 1702 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="g" /replace="t" /db_xref="dbSNP:199684776" variation 1704 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:200622623" variation 1712 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:189221075" variation 1716 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:199863372" variation 1767 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200661022" variation 1768 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201984059" variation 1773 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="" /replace="g" /db_xref="dbSNP:56092703" variation 1792 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:200097337" variation 1808 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:55829498" variation 1809 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:56175425" variation 1816 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:201220752" variation 1821 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201986384" variation 1822 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:199944797" variation 1847 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201100780" variation 1851 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:202141075" variation 1852 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:55638099" variation 1853 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="g" /replace="t" /db_xref="dbSNP:200999393" variation 1871 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:202200545" variation 1877 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:200317880" variation 1888 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /db_xref="dbSNP:201256811" variation 1892 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:199540825" variation 1924 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:55647070" variation 1927 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200255470" variation 1935 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /db_xref="dbSNP:201156584" variation 1956 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:199725306" variation 1974 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /db_xref="dbSNP:201006994" variation 1984 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201645636" variation 1985 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:199632962" variation 1989 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:185395115" variation 2015 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201889090" variation 2018 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:199869170" variation 2020 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:200954784" variation 2030 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:201972373" variation 2031 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /replace="g" /db_xref="dbSNP:200083187" variation 2037 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201363519" variation 2081 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="" /replace="a" /db_xref="dbSNP:55868412" variation 2095 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201963170" variation 2104 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:200257699" variation 2131 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:148989011" variation 2137 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201872518" variation 2146 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /replace="t" /db_xref="dbSNP:200180099" variation 2163 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="t" /db_xref="dbSNP:201377420" variation 2175 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:17844705" variation 2178 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:200480096" variation 2181 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:201754329" variation 2187 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:199528804" variation 2188 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="t" /db_xref="dbSNP:200594925" variation 2200 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201770115" variation 2232 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:199764281" variation 2240 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:55824260" variation 2245 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:17844706" variation 2272 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:17844707" variation 2276 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:56035337" variation 2347 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201107545" STS 2364..2548 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /standard_name="RH78907" /db_xref="UniSTS:35029" variation 2364 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:202047158" variation 2365 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="g" /db_xref="dbSNP:199884990" variation 2379 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:200811552" variation 2405 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="t" /db_xref="dbSNP:201795975" variation 2438 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:200077824" variation 2439 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:11574752" variation 2441 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:375016461" variation 2442 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201967136" variation 2445 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:72955950" variation 2447..2448 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="" /replace="cttaatgc" /db_xref="dbSNP:148832762" variation 2447 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:201473254" variation 2520 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="t" /db_xref="dbSNP:147749945" variation 2521 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /replace="t" /db_xref="dbSNP:200153685" variation 2544 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:201283841" variation 2558 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="c" /replace="t" /db_xref="dbSNP:199647047" variation 2565 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="g" /db_xref="dbSNP:200784640" variation 2586 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:201741488" variation 2611 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="c" /db_xref="dbSNP:199516582" variation 2639 /gene="CXCR2" /gene_synonym="CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB" /replace="a" /replace="t" /db_xref="dbSNP:181068104" ORIGIN
aagcagtggtgatagctgagaatatgcagccgttttctccttcctgggtacagtgctattctgcctagagctctgactaccacccaaccttgaggcacagtgaagacatcggtggccactccaataacagcaggtcacagctgctcttctggaggtgtcctacaggtgaaaagcccagcgacccagtcaggatttaagtttacctcaaaaatggaagattttaacatggagagtgacagctttgaagatttctggaaaggtgaagatcttagtaattacagttacagctctaccctgcccccttttctactagatgccgccccatgtgaaccagaatccctggaaatcaacaagtattttgtggtcattatctatgccctggtattcctgctgagcctgctgggaaactccctcgtgatgctggtcatcttatacagcagggtcggccgctccgtcactgatgtctacctgctgaacctagccttggccgacctactctttgccctgaccttgcccatctgggccgcctccaaggtgaatggctggatttttggcacattcctgtgcaaggtggtctcactcctgaaggaagtcaacttctatagtggcatcctgctactggcctgcatcagtgtggaccgttacctggccattgtccatgccacacgcacactgacccagaagcgctacttggtcaaattcatatgtctcagcatctggggtctgtccttgctcctggccctgcctgtcttacttttccgaaggaccgtctactcatccaatgttagcccagcctgctatgaggacatgggcaacaatacagcaaactggcggatgctgttacggatcctgccccagtcctttggcttcatcgtgccactgctgatcatgctgttctgctacggattcaccctgcgtacgctgtttaaggcccacatggggcagaagcaccgggccatgcgggtcatctttgctgtcgtcctcatcttcctgctctgctggctgccctacaacctggtcctgctggcagacaccctcatgaggacccaggtgatccaggagacctgtgagcgccgcaatcacatcgaccgggctctggatgccaccgagattctgggcatccttcacagctgcctcaaccccctcatctacgccttcattggccagaagtttcgccatggactcctcaagattctagctatacatggcttgatcagcaaggactccctgcccaaagacagcaggccttcctttgttggctcttcttcagggcacacttccactactctctaagacctcctgcctaagtgcagccccgtggggttcctcccttctcttcacagtcacattccaagcctcatgtccactggttcttcttggtctcagtgtcaatgcagcccccattgtggtcacaggaagtagaggaggccacgttcttactagtttcccttgcatggtttagaaagcttgccctggtgcctcaccccttgccataattactatgtcatttgctggagctctgcccatcctgcccctgagcccatggcactctatgttctaagaagtgaaaatctacactccagtgagacagctctgcatactcattaggatggctagtatcaaaagaaagaaaatcaggctggccaacggggtgaaaccctgtctctactaaaaatacaaaaaaaaaaaaaaattagccgggcgtggtggtgagtgcctgtaatcacagctacttgggaggctgagatgggagaatcacttgaacccgggaggcagaggttgcagtgagccgagattgtgcccctgcactccagcctgagcgacagtgagactctgtctcagtccatgaagatgtagaggagaaactggaactctcgagcgttgctgggggggattgtaaaatggtgtgaccactgcagaagacagtatggcagctttcctcaaaacttcagacatagaattaacacatgatcctgcaattccacttataggaattgacccacaagaaatgaaagcagggacttgaacccatatttgtacaccaatattcatagcagcttattcacaagacccaaaaggcagaagcaacccaaatgttcatcaatgaatgaatgaatggctaagcaaaatgtgatatgtacctaacgaagtatccttcagcctgaaagaggaatgaagtactcatacatgttacaacacggacgaaccttgaaaactttatgctaagtgaaataagccagacatcaacagataaatagtttatgattccacctacatgaggtactgagagtgaacaaatttacagagacagaaagcagaacagtgattaccagggactgaggggaggggagcatgggaagtgacggtttaatgggcacagggtttatgtttaggatgttgaaaaagttctgcagataaacagtagtgatagttgtaccgcaatgtgacttaatgccactaaattgacacttaaaaatggtttaaatggtcaattttgttatgtatattttatatcaatttaaaaaaaaacctgagccccaaaaggtattttaatcaccaaggctgattaaaccaaggctagaaccacctgcctatattttttgttaaatgatttcattcaatatcttttttttaataaaccatttttacttgggtgtttataaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726): GeneID:3579 -> Molecular function: GO:0004871 [signal transducer activity] evidence: IDA GeneID:3579 -> Molecular function: GO:0004918 [interleukin-8 receptor activity] evidence: IDA GeneID:3579 -> Molecular function: GO:0005515 [protein binding] evidence: IPI GeneID:3579 -> Molecular function: GO:0016494 [C-X-C chemokine receptor activity] evidence: IDA GeneID:3579 -> Molecular function: GO:0019959 [interleukin-8 binding] evidence: IPI GeneID:3579 -> Biological process: GO:0002407 [dendritic cell chemotaxis] evidence: TAS GeneID:3579 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA GeneID:3579 -> Biological process: GO:0006935 [chemotaxis] evidence: IDA GeneID:3579 -> Biological process: GO:0006954 [inflammatory response] evidence: TAS GeneID:3579 -> Biological process: GO:0006968 [cellular defense response] evidence: IDA GeneID:3579 -> Biological process: GO:0007165 [signal transduction] evidence: IDA GeneID:3579 -> Biological process: GO:0007166 [cell surface receptor signaling pathway] evidence: IDA GeneID:3579 -> Biological process: GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] evidence: IDA GeneID:3579 -> Biological process: GO:0007204 [elevation of cytosolic calcium ion concentration] evidence: IEA GeneID:3579 -> Biological process: GO:0008284 [positive regulation of cell proliferation] evidence: IDA GeneID:3579 -> Biological process: GO:0030593 [neutrophil chemotaxis] evidence: IDA GeneID:3579 -> Biological process: GO:0031623 [receptor internalization] evidence: IDA GeneID:3579 -> Biological process: GO:0038112 [interleukin-8-mediated signaling pathway] evidence: IDA GeneID:3579 -> Biological process: GO:0042119 [neutrophil activation] evidence: IDA GeneID:3579 -> Cellular component: GO:0005622 [intracellular] evidence: IDA GeneID:3579 -> Cellular component: GO:0005886 [plasma membrane] evidence: TAS GeneID:3579 -> Cellular component: GO:0005887 [integral to plasma membrane] evidence: TAS GeneID:3579 -> Cellular component: GO:0009986 [cell surface] evidence: IDA GeneID:3579 -> Cellular component: GO:0016020 [membrane] evidence: IDA GeneID:3579 -> Cellular component: GO:0042629 [mast cell granule] evidence: IDA
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