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2024-04-27 07:30:19, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001161407 4606 bp mRNA linear PRI 15-JUN-2013
DEFINITION Homo sapiens Nedd4 family interacting protein 2 (NDFIP2),
transcript variant 2, mRNA.
ACCESSION NM_001161407
VERSION NM_001161407.1 GI:239046742
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4606)
CONSRTM GENDEP Investigators; MARS Investigators; STAR*D Investigators
TITLE Common genetic variation and antidepressant efficacy in major
depressive disorder: a meta-analysis of three genome-wide
pharmacogenetic studies
JOURNAL Am J Psychiatry 170 (2), 207-217 (2013)
PUBMED 23377640
REFERENCE 2 (bases 1 to 4606)
AUTHORS Mund,T. and Pelham,H.R.
TITLE Regulation of PTEN/Akt and MAP kinase signaling pathways by the
ubiquitin ligase activators Ndfip1 and Ndfip2
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 107 (25), 11429-11434 (2010)
PUBMED 20534535
REMARK GeneRIF: PTEN/Akt and MAP kinase signaling pathways are regulated
by the ubiquitin ligase activators Ndfip1 and Ndfip2
REFERENCE 3 (bases 1 to 4606)
AUTHORS Low,S.K., Kuchiba,A., Zembutsu,H., Saito,A., Takahashi,A., Kubo,M.,
Daigo,Y., Kamatani,N., Chiku,S., Totsuka,H., Ohnami,S., Hirose,H.,
Shimada,K., Okusaka,T., Yoshida,T., Nakamura,Y. and Sakamoto,H.
TITLE Genome-wide association study of pancreatic cancer in Japanese
population
JOURNAL PLoS ONE 5 (7), E11824 (2010)
PUBMED 20686608
REMARK Publication Status: Online-Only
REFERENCE 4 (bases 1 to 4606)
AUTHORS Mund,T. and Pelham,H.R.
TITLE Control of the activity of WW-HECT domain E3 ubiquitin ligases by
NDFIP proteins
JOURNAL EMBO Rep. 10 (5), 501-507 (2009)
PUBMED 19343052
REMARK GeneRIF: Data show that the small PY-containing membrane proteins,
NDFIP1 and NDFIP2 (NEDD4 family-interacting proteins), activate the
catalytic activity of ITCH and of several other HECT ligases by
binding to them.
REFERENCE 5 (bases 1 to 4606)
AUTHORS Foot,N.J., Dalton,H.E., Shearwin-Whyatt,L.M., Dorstyn,L., Tan,S.S.,
Yang,B. and Kumar,S.
TITLE Regulation of the divalent metal ion transporter DMT1 and iron
homeostasis by a ubiquitin-dependent mechanism involving Ndfips and
WWP2
JOURNAL Blood 112 (10), 4268-4275 (2008)
PUBMED 18776082
REFERENCE 6 (bases 1 to 4606)
AUTHORS Shearwin-Whyatt,L.M., Brown,D.L., Wylie,F.G., Stow,J.L. and
Kumar,S.
TITLE N4WBP5A (Ndfip2), a Nedd4-interacting protein, localizes to
multivesicular bodies and the Golgi, and has a potential role in
protein trafficking
JOURNAL J. Cell. Sci. 117 (PT 16), 3679-3689 (2004)
PUBMED 15252135
REMARK GeneRIF: N4WBP5A acts as an adaptor to recruit Nedd4 family
ubiquitin-protein ligases to the protein trafficking machinery
REFERENCE 7 (bases 1 to 4606)
AUTHORS Dunham,A., Matthews,L.H., Burton,J., Ashurst,J.L., Howe,K.L.,
Ashcroft,K.J., Beare,D.M., Burford,D.C., Hunt,S.E.,
Griffiths-Jones,S., Jones,M.C., Keenan,S.J., Oliver,K., Scott,C.E.,
Ainscough,R., Almeida,J.P., Ambrose,K.D., Andrews,D.T.,
Ashwell,R.I., Babbage,A.K., Bagguley,C.L., Bailey,J., Bannerjee,R.,
Barlow,K.F., Bates,K., Beasley,H., Bird,C.P., Bray-Allen,S.,
Brown,A.J., Brown,J.Y., Burrill,W., Carder,C., Carter,N.P.,
Chapman,J.C., Clamp,M.E., Clark,S.Y., Clarke,G., Clee,C.M.,
Clegg,S.C., Cobley,V., Collins,J.E., Corby,N., Coville,G.J.,
Deloukas,P., Dhami,P., Dunham,I., Dunn,M., Earthrowl,M.E.,
Ellington,A.G., Faulkner,L., Frankish,A.G., Frankland,J.,
French,L., Garner,P., Garnett,J., Gilbert,J.G., Gilson,C.J.,
Ghori,J., Grafham,D.V., Gribble,S.M., Griffiths,C., Hall,R.E.,
Hammond,S., Harley,J.L., Hart,E.A., Heath,P.D., Howden,P.J.,
Huckle,E.J., Hunt,P.J., Hunt,A.R., Johnson,C., Johnson,D., Kay,M.,
Kimberley,A.M., King,A., Laird,G.K., Langford,C.J., Lawlor,S.,
Leongamornlert,D.A., Lloyd,D.M., Lloyd,C., Loveland,J.E.,
Lovell,J., Martin,S., Mashreghi-Mohammadi,M., McLaren,S.J.,
McMurray,A., Milne,S., Moore,M.J., Nickerson,T., Palmer,S.A.,
Pearce,A.V., Peck,A.I., Pelan,S., Phillimore,B., Porter,K.M.,
Rice,C.M., Searle,S., Sehra,H.K., Shownkeen,R., Skuce,C.D.,
Smith,M., Steward,C.A., Sycamore,N., Tester,J., Thomas,D.W.,
Tracey,A., Tromans,A., Tubby,B., Wall,M., Wallis,J.M., West,A.P.,
Whitehead,S.L., Willey,D.L., Wilming,L., Wray,P.W., Wright,M.W.,
Young,L., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E., Beck,S.,
Bentley,D.R., Rogers,J. and Ross,M.T.
TITLE The DNA sequence and analysis of human chromosome 13
JOURNAL Nature 428 (6982), 522-528 (2004)
PUBMED 15057823
REFERENCE 8 (bases 1 to 4606)
AUTHORS Cristillo,A.D., Nie,L., Macri,M.J. and Bierer,B.E.
TITLE Cloning and characterization of N4WBP5A, an inducible,
cyclosporine-sensitive, Nedd4-binding protein in human T
lymphocytes
JOURNAL J. Biol. Chem. 278 (36), 34587-34597 (2003)
PUBMED 12796489
REMARK GeneRIF: N4WBP5A may play a regulatory role in modulating Nedd4
activity at the level of the Golgi apparatus in T lymphocytes
REFERENCE 9 (bases 1 to 4606)
AUTHORS Matsuda,A., Suzuki,Y., Honda,G., Muramatsu,S., Matsuzaki,O.,
Nagano,Y., Doi,T., Shimotohno,K., Harada,T., Nishida,E., Hayashi,H.
and Sugano,S.
TITLE Large-scale identification and characterization of human genes that
activate NF-kappaB and MAPK signaling pathways
JOURNAL Oncogene 22 (21), 3307-3318 (2003)
PUBMED 12761501
REFERENCE 10 (bases 1 to 4606)
AUTHORS Konstas,A.A., Shearwin-Whyatt,L.M., Fotia,A.B., Degger,B.,
Riccardi,D., Cook,D.I., Korbmacher,C. and Kumar,S.
TITLE Regulation of the epithelial sodium channel by N4WBP5A, a novel
Nedd4/Nedd4-2-interacting protein
JOURNAL J. Biol. Chem. 277 (33), 29406-29416 (2002)
PUBMED 12050153
REMARK GeneRIF: role in regulating epithelial sodium channel
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AL355603.17, AK294839.1, AL136442.12 and BM976935.1.
Transcript Variant: This variant (2) uses an alternate in-frame
splice site in the 3' coding region compared to variant 1. This
results in a shorter isoform (2) compared to isoform 1.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data to make the sequence consistent with the
reference genome assembly. The genomic coordinates used for the
transcript record were based on transcript alignments.
##Evidence-Data-START##
Transcript exon combination :: AK294839.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025082 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-329 AL355603.17 57990-58318
330-1713 AK294839.1 1-1384
1714-3876 AL136442.12 125243-127405 c
3877-4606 BM976935.1 1-730 c
FEATURES Location/Qualifiers
source 1..4606
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="13"
/map="13q31.1"
gene 1..4606
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/note="Nedd4 family interacting protein 2"
/db_xref="GeneID:54602"
/db_xref="HGNC:18537"
/db_xref="MIM:610041"
exon 1..401
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
variation 79
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="g"
/db_xref="dbSNP:377642299"
CDS 81..1031
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/note="isoform 2 is encoded by transcript variant 2; NEDD4
WW domain-binding protein 5A; NF-kappa-B-activating
protein 413; MAPK-activating protein PM04 PM05 PM06 PM07;
NEDD4 family-interacting protein 2; putative
NF-kappa-B-activating protein 413; putative
MAPK-activating protein PM04/PM05/PM06/PM07"
/codon_start=1
/product="NEDD4 family-interacting protein 2 isoform 2"
/protein_id="NP_001154879.1"
/db_xref="GI:239046743"
/db_xref="GeneID:54602"
/db_xref="HGNC:18537"
/db_xref="MIM:610041"
/translation="
MARRRSQRVCASGPSMLNSARGAPELLRGTATNAEVSAAAAGATGSEELPPGDRGCRNGGGRGPAATTSSTGVAVGAEHGEDSLSRKPDPEPGRMDHHQPGTGRYQVLLNEEDNSESSAIEQPPTSNPAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFTGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVRNMSESMAAAHRTRYFFLL
"
misc_feature <594..1013
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/note="Protein of unknown function (DUF2370); Region:
DUF2370; pfam10176"
/db_xref="CDD:192470"
variation 97
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:143536057"
variation 153
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:3814278"
variation 179
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="g"
/db_xref="dbSNP:183195124"
variation 196
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:113662422"
variation 249
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="t"
/db_xref="dbSNP:201081260"
variation 283
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="c"
/db_xref="dbSNP:375938709"
variation 292
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="c"
/db_xref="dbSNP:371311268"
variation 294
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:370820502"
variation 342
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:368971046"
exon 402..567
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
variation 416
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:149865944"
variation 442
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:144950614"
variation 450
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:55887763"
variation 468
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:373903171"
variation 469
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:146047464"
variation 470
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:368345034"
variation 487
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:11549502"
variation 488
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:371388745"
variation 535
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:61735407"
variation 540
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:371917287"
variation 561
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:371287967"
exon 568..701
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
variation 580
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:143612506"
variation 581
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:117933987"
variation 582
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:141843405"
variation 592
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:368610434"
variation 596
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:150182671"
variation 611
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:138905931"
variation 615
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:142039160"
variation 648
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="g"
/db_xref="dbSNP:371885469"
variation 669
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:375021774"
variation 677
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="t"
/db_xref="dbSNP:146142126"
exon 702..795
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
variation 716
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="g"
/replace="t"
/db_xref="dbSNP:139711651"
exon 796..860
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
variation 842
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:374117696"
exon 861..927
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
variation 878
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:148785504"
variation 879
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:373812761"
exon 928..1033
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
exon 1034..4595
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/inference="alignment:Splign:1.39.8"
variation 1065
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="g"
/db_xref="dbSNP:193206553"
variation 1068
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:183469703"
variation 1151
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:1212082"
STS 1160..1409
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/standard_name="STS-AA037467"
/db_xref="UniSTS:6301"
variation 1163
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="g"
/replace="t"
/db_xref="dbSNP:17071601"
variation 1191
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:59945183"
variation 1402
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:368513684"
variation 1543
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:41288270"
variation 1558
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:74922628"
STS 1610..1805
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/standard_name="WI-22692"
/db_xref="UniSTS:2937"
variation 1618
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:150468706"
variation 1635
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="c"
/db_xref="dbSNP:116166707"
STS 1652..1869
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/standard_name="RH44816"
/db_xref="UniSTS:90128"
variation 1725..1726
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace=""
/replace="ac"
/db_xref="dbSNP:34603928"
variation 1726..1727
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace=""
/replace="ac"
/db_xref="dbSNP:72108250"
variation 1754
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:12585004"
variation 1762..1763
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace=""
/replace="aa"
/db_xref="dbSNP:34511187"
variation 1841
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:700396"
variation 1857
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:8000301"
STS 1868..2027
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/standard_name="RH45196"
/db_xref="UniSTS:80258"
variation 1919
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="g"
/replace="t"
/db_xref="dbSNP:370849898"
variation 2018
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:7981574"
variation 2104
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:187357067"
variation 2132
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:74100740"
STS 2203..2346
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/standard_name="RH78426"
/db_xref="UniSTS:9203"
variation 2221
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="g"
/replace="t"
/db_xref="dbSNP:41288272"
variation 2453
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="g"
/replace="t"
/db_xref="dbSNP:191800517"
variation 2509
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:183923591"
variation 2542
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace=""
/replace="a"
/db_xref="dbSNP:375300709"
variation 2700
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:188416304"
variation 2718
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:149221742"
variation 2927
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:1044647"
variation 2943..2944
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace=""
/replace="g"
/db_xref="dbSNP:34370878"
variation 2965
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:192415007"
variation 3012
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:9924"
STS 3055..3239
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/standard_name="RH93391"
/db_xref="UniSTS:87224"
variation 3067
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:7988143"
variation 3173
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:368435397"
variation 3375
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="t"
/db_xref="dbSNP:146884822"
variation 3387
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:139061774"
variation 3424
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="g"
/db_xref="dbSNP:143034581"
variation 3491
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:147451134"
variation 3622
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="g"
/db_xref="dbSNP:148125298"
variation 3705
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="c"
/db_xref="dbSNP:372106051"
variation 3711
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:2760102"
variation 3857
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:184269526"
variation 3994
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:116562947"
variation 4089
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:141886349"
variation 4133
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="a"
/replace="g"
/db_xref="dbSNP:115975942"
variation 4205
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:190434266"
variation 4442
/gene="NDFIP2"
/gene_synonym="N4WBP5A"
/replace="c"
/replace="t"
/db_xref="dbSNP:368029245"
ORIGIN
acaacctagacagctcccccggacttgccttacttttccatctcctcccacccagctataccctcccactggcggcgcggatggcacgccggcggagccagcgagtctgcgcgagcggtccgagcatgctcaatagcgcgcgcggcgccccggagcttctccgcggaaccgcgaccaacgcggaggtctcggcggccgctgcgggagccacaggaagtgaagagcttccgccgggagaccgcggctgcaggaacggaggcggaaggggccctgcggcgacgacgtcgtcgacgggggtggccgtgggagctgagcacggagaagactccctctctcggaagccggatcccgagccgggcaggatggatcaccaccagccggggactgggcgctaccaggtgcttcttaatgaagaggataactcagaatcatcggctatagagcagccacctacttcaaacccagcaccgcagattgtgcaggctgcgtcttcagcaccagcacttgaaactgactcttcccctccaccatatagtagtattactgtggaagtacctacaacttcagatacagaagtttacggtgagttttatcccgtgccacctccctatagcgttgctacctctcttcctacatacgatgaagctgagaaggctaaagctgctgcaatggcagctgcagcagcagaaacatctcaaagaattcaggaggaagagtgtccaccaagagatgacttcagtgatgcagaccagctcagagtggggaatgatggcattttcatgctggcatttttcactggaaggtatggtgctatctgcggatttggcctttccttgatcaaatggatccttattgtcaggttttctgattattttactggatatttcaatggacagtattggctttggtggatatttcttgtacttggcctgctccttttcttcagaggatttgttaattatctaaaagtcagaaacatgtctgaaagtatggcagctgctcatagaacaaggtatttcttcttattgtagagactgcatcaacccgacattcctttcttataccaatgtgaaatttccagatcatctgtaaacctacaactttaatagaagactactaataacagaagacaaattagtgaagaaaagacggagtttcgaaattgaatggcagggtggtttttgcttacaagccatttctgttcattctttaagtatctatatttcatttgttttgcacatatgcatatgtgcccatttaagatatttgcatatacttgatagaaaccataaagttgtagcagttaagtccagtcacatttggttaatcagtgtttgatataattgaaagagttgagtggataaacagtcttccagcttgtaaatgccattgacttctgacctgacatttagtataataaaaatgaaattcttaaccatgtcaaatgatttagtttctggctcttagactcatctggcagttctacacatgaaacatcttttgttatataaggtgtattgaaacctgcagtgctgattattagaaaggatttgtcagatttttgaacatgatatttacattattatttaggaaaactcttcctgtaaataaccatgcataacttactttctgcaatgttttcttagaaattgtgtccagatagctttcactaattttaaattaagtgaactaaatatatatgtgtatatgtatacacatatatatacacacacacatatatatatttagaaacgtgagtgttaaagatagaatttgttttaggacaaattttaagaaaatgtgggaataccaaatgtcctttataagaaaaataaattttattttaagggacatactagttttagggattttcagatgggaagctgcatttttaggattgcccatcttaagagatcttgcaggaagagattgtattagatattatatttatttcatttaagataattttcaaagttaattttctaaataagataattctcatttgtgtttgtcttttaaaaggccaataaaatatctttcagtatcattgtaataattttttagagtttaatttgtaaagcttagcaaataaaatcttgtactatgaatagcttcttgctttatgactttaggattaacttgtaaaaaacatatcctgaactgagatatgcaaaatactcattttcaagttatggaaatgtgtttgtggcatataggactgtggggtctgtgtgtgtagtgagagtgtgtagccactattataactggaatttaatttacattcataaactactatatttcccatcttgcaaatcattttatgtctcatctgtttttcctttcggttatatctttggttttgaataccaacatttaaaatgatggtattttatcttttaaacttaaaaattatttaatacagctatatggaccttataaaattgatttcttatttattattagacattactactaaaaggtacatctaactattcagggacatttttccatttccaaaaaataaaatttattatgctttataacctcttctgtattttctaattttttcattgtctttgataaataaaacagttttgttttgctaatatagcctattttttgttttgtctcattcagtttactttcctgcgtagaatttttattgttatattaaaatttttattgttgtattaaagtacctgtgttacaccccttgaagtaagacagtagcatggggtaaagaaaaaatatttagtttagttgcctaatttggaagttaattaaaattaaactgtactaataacatattcaaactcatgctggatctctttcatattaatttcttatagacctgtactttattctttcaataatttttaaatgaaattaagctttgctacatggtaattaaataattactaggaagcttagctatcaaacatcgacttactaaaatttcattttagcttttatggtatatgtgcttgttttctgaatatggatacatgttacttttgatccagcatcaaaacttcactttttgttttgacttttccccccaaatctgtaaggttcaagtatacatattactgaatcctctataattggcataattcaatggtagccttaaatctcatcatgtaagcaggggaatcagaatgttattttcaagaacttaatgttcccttcagatatataaaatcctgcatacttcatttcctgtgagcttgaacagctgctgttgtgttttggggatgcttgatcatctttgcactctgccttaaagattgaaaaatcaaaactcttgttagggtatctaaacatttttgagtgtgaactggggattggaagttaatacaaaaaaatttcaaattatttctattgtaaatgaataagctagtcatggctaggataatccattttcatgtatttatgcaataaactgaattttaaggcaaaaacaacacttttctatatagtgtatgcaggacagattttagaaacttagattaaaatacaaatcccattacatttggttaaaatgaaaatctctgcttaatggaaaaaatactaatctttagcctattttgagtctataagatatatttcattttagacatgccttctaagttgttcacagatttttacctgctaaaacaatattatttccagtaaaacctctcctaacaggaaaagtggagttcaaaatatccaattggagaaaaattcagagttccttcattaaatataatttttttcatctagtatgtactatttcaagaagtgcaaaaagtaatgatagtgaatgtgataccatacttaactaaggtaatatatatccttagtttgctcaaaagagtcctggttattcctgttttctcagcttaatagtgcctcatcgtactctcaaaagtgttctaatttggaggataagttatatgatcatcctgtgtataattgtagactgtaccaagaagcaactaccttagctccactgccctttgagggatggaactggggtaagggcaggagccagttattattgccacagtgttttctaatgaaccatttggcctgtagaagaggaatagtattttttttaatagttgtatttgaatgattccagcttatcgtaaatactaaactgaatggcttttatatttttaactgctgttaaatgttattttagcatttattagttgtttattatttaattcttcaaatagtcatatgaaaacatatatttgataaaggtcaattgttagatgataatgtgccattcattatcataggaatgtccttgcccatatataaaacatgctggcatgtattttacttgttaataaagttgtatagatgtggaagtgtgaacctgtgatgcatccttttcaaaatcagtttaagattcgcatattatcatgactgtgacctcactaaactgtttatgtgacaaacctttcaagattggagatgaaaacaacacttgtgaaattaggttggggttgcaacatcttttaacttctcagttatttgtatgtcaggagacagattgtggtttaattttaataaacaaaatatcatctttttgaaaataaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:54602 -> Molecular function: GO:0004871 [signal transducer activity] evidence: IMP
GeneID:54602 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:54602 -> Molecular function: GO:0050699 [WW domain binding] evidence: IPI
GeneID:54602 -> Biological process: GO:0007165 [signal transduction] evidence: IMP
GeneID:54602 -> Biological process: GO:0010629 [negative regulation of gene expression] evidence: IMP
GeneID:54602 -> Biological process: GO:0031398 [positive regulation of protein ubiquitination] evidence: IMP
GeneID:54602 -> Biological process: GO:0032410 [negative regulation of transporter activity] evidence: IMP
GeneID:54602 -> Biological process: GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB cascade] evidence: IMP
GeneID:54602 -> Biological process: GO:0051224 [negative regulation of protein transport] evidence: IMP
GeneID:54602 -> Cellular component: GO:0000139 [Golgi membrane] evidence: IEA
GeneID:54602 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:54602 -> Cellular component: GO:0005739 [mitochondrion] evidence: IDA
GeneID:54602 -> Cellular component: GO:0005783 [endoplasmic reticulum] evidence: IDA
GeneID:54602 -> Cellular component: GO:0005794 [Golgi apparatus] evidence: IDA
GeneID:54602 -> Cellular component: GO:0016021 [integral to membrane] evidence: IEA
GeneID:54602 -> Cellular component: GO:0032585 [multivesicular body membrane] evidence: IEA
GeneID:54602 -> Cellular component: GO:0048471 [perinuclear region of cytoplasm] evidence: IDA
by
@meso_cacase at
DBCLS
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