2024-04-19 18:13:14, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001145371 6217 bp mRNA linear PRI 17-APR-2013 DEFINITION Homo sapiens protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 5, mRNA. ACCESSION NM_001145371 VERSION NM_001145371.1 GI:223941887 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 6217) AUTHORS Hou,S., Suresh,P.S., Qi,X., Lepp,A., Mirza,S.P. and Chen,G. TITLE p38gamma Mitogen-activated protein kinase signals through phosphorylating its phosphatase PTPH1 in regulating ras protein oncogenesis and stress response JOURNAL J. Biol. Chem. 287 (33), 27895-27905 (2012) PUBMED 22730326 REMARK GeneRIF: p38gamma Mitogen-activated protein kinase signals through phosphorylating its phosphatase PTPH1 in regulating ras protein oncogenesis and stress response. REFERENCE 2 (bases 1 to 6217) AUTHORS Jung,Y., Kim,P., Jung,Y., Keum,J., Kim,S.N., Choi,Y.S., Do,I.G., Lee,J., Choi,S.J., Kim,S., Lee,J.E., Kim,J., Lee,S. and Kim,J. TITLE Discovery of ALK-PTPN3 gene fusion from human non-small cell lung carcinoma cell line using next generation RNA sequencing JOURNAL Genes Chromosomes Cancer 51 (6), 590-597 (2012) PUBMED 22334442 REMARK GeneRIF: The fusion transcript of ALK and PTPN3 identified resulted from translocation of a part of ALK gene into the third intron of PTPN3. Analysis of the transcript sequence indicates that no protein with any enzymatic activity is produced. REFERENCE 3 (bases 1 to 6217) AUTHORS Zhi,H.Y., Hou,S.W., Li,R.S., Basir,Z., Xiang,Q., Szabo,A. and Chen,G. TITLE PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization JOURNAL Oncogene 30 (14), 1706-1715 (2011) PUBMED 21119599 REMARK GeneRIF: PTPH1 stimulated breast cancer growth through regulating vitamin D receptor expression. PTPH1 was overexpressed in primary breast cancer and levels of its protein expression positively correlated with clinical metastasis. REFERENCE 4 (bases 1 to 6217) AUTHORS Hou,S.W., Zhi,H.Y., Pohl,N., Loesch,M., Qi,X.M., Li,R.S., Basir,Z. and Chen,G. TITLE PTPH1 dephosphorylates and cooperates with p38gamma MAPK to increase ras oncogenesis through PDZ-mediated interaction JOURNAL Cancer Res. 70 (7), 2901-2910 (2010) PUBMED 20332238 REMARK GeneRIF: PTPH1 plays a role in Ras-dependent malignant growth by a mechanism depending on its p38gamma-binding activity. Ras increases p38gamma and PTPH1 expression and there is a coupling of increased p38gamma and PTPH1 protein expression in colon cancer. REFERENCE 5 (bases 1 to 6217) AUTHORS Barr,A.J., Ugochukwu,E., Lee,W.H., King,O.N., Filippakopoulos,P., Alfano,I., Savitsky,P., Burgess-Brown,N.A., Muller,S. and Knapp,S. TITLE Large-scale structural analysis of the classical human protein tyrosine phosphatome JOURNAL Cell 136 (2), 352-363 (2009) PUBMED 19167335 REFERENCE 6 (bases 1 to 6217) AUTHORS Zhang,S.H., Kobayashi,R., Graves,P.R., Piwnica-Worms,H. and Tonks,N.K. TITLE Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3beta protein JOURNAL J. Biol. Chem. 272 (43), 27281-27287 (1997) PUBMED 9341175 REFERENCE 7 (bases 1 to 6217) AUTHORS Ikuta,S., Itoh,F., Hinoda,Y., Toyota,M., Makiguchi,Y., Imai,K. and Yachi,A. TITLE Expression of cytoskeletal-associated protein tyrosine phosphatase PTPH1 mRNA in human hepatocellular carcinoma JOURNAL J. Gastroenterol. 29 (6), 727-732 (1994) PUBMED 7874267 REFERENCE 8 (bases 1 to 6217) AUTHORS Itoh,F., Ikuta,S., Hinoda,Y., Arimura,Y., Ohe,M., Adachi,M., Ariyama,T., Inazawa,J., Imai,K. and Yachi,A. TITLE Expression and chromosomal assignment of PTPH1 gene encoding a cytosolic protein tyrosine phosphatase homologous to cytoskeletal-associated proteins JOURNAL Int. J. Cancer 55 (6), 947-951 (1993) PUBMED 8253532 REFERENCE 9 (bases 1 to 6217) AUTHORS Arimura,Y., Hinoda,Y., Itoh,F., Takekawa,M., Tsujisaki,M., Adachi,M., Imai,K. and Yachi,A. TITLE cDNA cloning of new protein tyrosine phosphatases in the human colon JOURNAL Tumour Biol. 13 (3), 180-186 (1992) PUBMED 1626183 REFERENCE 10 (bases 1 to 6217) AUTHORS Yang,Q. and Tonks,N.K. TITLE Isolation of a cDNA clone encoding a human protein-tyrosine phosphatase with homology to the cytoskeletal-associated proteins band 4.1, ezrin, and talin JOURNAL Proc. Natl. Acad. Sci. U.S.A. 88 (14), 5949-5953 (1991) PUBMED 1648725 COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC342461.1, AK296388.1, BC126117.1, BC033716.1, DB173093.1, AK096975.1, AL359963.29 and BU624870.1. Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]. Transcript Variant: This variant (5) differs in the 5' UTR, and initiates translation from an in-frame downstream AUG, resulting in an isoform (5) with a shorter N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK296388.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025081, ERS025082 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-557 DC342461.1 1-557 558-918 AK296388.1 484-844 919-2915 BC126117.1 1346-3342 2916-3657 BC033716.1 1459-2200 3658-3995 DB173093.1 253-590 3996-4479 AK096975.1 196-679 4480-4519 AL359963.29 93827-93866 c 4520-6194 AK096975.1 702-2376 6195-6217 BU624870.1 1-23 c FEATURES Location/Qualifiers source 1..6217 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="9" /map="9q31" gene 1..6217 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /note="protein tyrosine phosphatase, non-receptor type 3" /db_xref="GeneID:5774" /db_xref="HGNC:9655" /db_xref="MIM:176877" exon 1..423 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(101) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:184825084" variation complement(175) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:371879894" variation complement(315) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:376129933" variation complement(319) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="c" /db_xref="dbSNP:371559773" variation complement(322) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:201906486" misc_feature 355..357 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /note="upstream in-frame stop codon" variation complement(367) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:192064945" variation complement(371) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:199956141" variation complement(389) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:146954653" variation complement(413) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:141258824" exon 424..596 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(429) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="t" /db_xref="dbSNP:376928867" CDS 457..2337 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /EC_number="3.1.3.48" /note="isoform 5 is encoded by transcript variant 5; cytoskeletal-associated protein tyrosine phosphatase; tyrosine-protein phosphatase non-receptor type 3; protein-tyrosine phosphatase H1" /codon_start=1 /product="tyrosine-protein phosphatase non-receptor type 3 isoform 5" /protein_id="NP_001138843.1" /db_xref="GI:223941888" /db_xref="GeneID:5774" /db_xref="HGNC:9655" /db_xref="MIM:176877" /translation="
MLNYRSCKNLWKSCVEHHTFFQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTEDASQYYCDKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRRAVRSFADFKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPDPPDVMNHGGFHIQCQSEDCTIAYVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQMLDPS
" misc_feature <457..531 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /note="FERM C-terminal PH-like domain; Region: FERM_C; pfam09380" /db_xref="CDD:204221" misc_feature 1117..1380 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /note="PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal)...; Region: PDZ_signaling; cd00992" /db_xref="CDD:29049" misc_feature order(1153..1164,1168..1170,1318..1323,1330..1335) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /note="protein binding site [polypeptide binding]; other site" /db_xref="CDD:29049" misc_feature 1540..2295 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /note="Protein tyrosine phosphatase, catalytic domain; Region: PTPc; smart00194" /db_xref="CDD:197567" misc_feature 1609..2292 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /note="Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cd00047" /db_xref="CDD:28929" misc_feature order(2026..2028,2116..2121,2128..2130,2137..2142) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /note="active site" /db_xref="CDD:28929" variation complement(470) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:374370776" variation complement(487) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:372409514" variation complement(497) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:147767465" variation complement(499) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:368204104" variation complement(532) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:374798614" variation complement(534) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:144167957" variation complement(551) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:61736875" variation complement(583) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:370526852" exon 597..731 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(599) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:376647767" variation complement(615) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:201919688" variation complement(623) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:151104500" variation complement(633) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="c" /db_xref="dbSNP:373387477" variation complement(634) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:142980957" variation complement(640) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:369138815" variation complement(666) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:374793150" variation complement(707) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:371270540" variation complement(728) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:148558305" exon 732..908 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(732) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="g" /replace="t" /db_xref="dbSNP:144812815" variation complement(733) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="c" /db_xref="dbSNP:185821807" variation complement(747) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:142016536" variation complement(749) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:201397922" variation complement(770) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="g" /replace="t" /db_xref="dbSNP:140094288" variation complement(783) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:146095498" variation complement(816) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:142732873" variation complement(820) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:10979858" variation complement(822) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:372178642" variation complement(834) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="g" /replace="t" /db_xref="dbSNP:181688303" variation complement(836) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:368525928" variation complement(840) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:138148171" variation complement(853) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:374202196" variation complement(869) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:372151791" variation complement(870) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:367948677" variation complement(892) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:375004037" variation complement(893) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:370298571" variation complement(900) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:116205878" variation complement(901) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:200101992" exon 909..1095 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(918) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:199620488" variation complement(919) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:141809051" variation complement(930) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:17803052" variation complement(948) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:146992805" variation complement(1012) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:141350094" variation complement(1013) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:138707755" variation complement(1022) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:375545706" variation complement(1041) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="c" /db_xref="dbSNP:147174947" variation complement(1050) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:377369883" variation complement(1066) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:373058480" variation complement(1083) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:145875554" exon 1096..1173 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(1099) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:372363344" variation complement(1101) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="t" /db_xref="dbSNP:368144041" variation complement(1121) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:113237352" variation complement(1123) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="g" /replace="t" /db_xref="dbSNP:376855050" variation complement(1128) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="c" /db_xref="dbSNP:371910658" variation complement(1130) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:189241432" exon 1174..1230 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(1201) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:183458658" variation complement(1209) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:149023035" variation complement(1210) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="c" /db_xref="dbSNP:372689393" variation complement(1211) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:144915998" exon 1231..1387 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(1233) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:150061689" variation complement(1236) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:200410469" variation complement(1258) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:140628740" variation complement(1289) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:181792746" variation complement(1293) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:146841512" variation complement(1300) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:59324117" variation complement(1314) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:140140279" variation complement(1328) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:146077461" variation complement(1334) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:201209769" variation complement(1352) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:144304313" variation complement(1358) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:199759803" exon 1388..1548 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(1393) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:148505458" variation complement(1395) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:374405230" variation complement(1410) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="c" /replace="g" /db_xref="dbSNP:7859962" variation complement(1431) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:34302609" variation complement(1455) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:150353247" variation complement(1467) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:371992176" exon 1549..1639 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(1551) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:147437194" variation complement(1570) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:371372947" variation complement(1622) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="t" /db_xref="dbSNP:377718578" exon 1640..1701 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(1660) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:76416062" variation complement(1695) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:138839766" variation complement(1700) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:145864054" exon 1702..1848 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(1740) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:140802922" variation complement(1758) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:147976452" variation complement(1760) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:189256306" variation complement(1763) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:143462283" variation complement(1804) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:199692080" variation complement(1827) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:148827369" exon 1849..1977 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(1863) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:146869100" variation complement(1876) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:375763821" variation complement(1881) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:2304742" variation complement(1882) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:10116806" variation complement(1896) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:373493427" variation complement(1899) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:146618446" variation complement(1915) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="t" /db_xref="dbSNP:150008661" variation complement(1939) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:370019146" variation complement(1969) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="c" /db_xref="dbSNP:139321235" exon 1978..2123 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(2016) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:150855452" variation complement(2019) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:146486489" variation complement(2044) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="g" /replace="t" /db_xref="dbSNP:371886206" variation complement(2046) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:367766327" variation complement(2052) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:140717531" variation complement(2071) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="t" /db_xref="dbSNP:375434242" variation complement(2096) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:374209870" variation complement(2100) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:371197800" variation complement(2101) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:147420952" variation complement(2106) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:142937669" variation complement(2107) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:138828543" variation complement(2118) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:368814204" exon 2124..2259 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(2138) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:372894176" variation complement(2165) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:370374314" variation complement(2227) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:201209437" variation complement(2239) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:201640227" variation complement(2243) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:200077324" variation complement(2250) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="g" /replace="t" /db_xref="dbSNP:147200776" exon 2260..6199 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /inference="alignment:Splign:1.39.8" variation complement(2276) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:149479153" variation complement(2286) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:137963642" variation complement(2316) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:370012185" variation complement(2325) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:200403602" variation complement(2327) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:150328766" variation complement(2341) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:200494712" variation complement(2344) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:377490884" variation complement(2352) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:374288172" variation complement(2379) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:138931600" variation complement(2415) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:371464957" variation complement(2535) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:150282450" variation complement(2565) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:180926631" variation complement(2600) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:189242626" variation complement(2675) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:140930516" variation complement(2706) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:185827185" variation complement(2832) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="g" /replace="t" /db_xref="dbSNP:151038868" variation complement(2885) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:114131793" STS 2929..3625 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /standard_name="PTPN3_2445" /db_xref="UniSTS:280941" variation complement(2994) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="t" /db_xref="dbSNP:115197904" variation complement(3017) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:143684539" variation complement(3122) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:41278397" variation complement(3129) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:140622120" variation complement(3149) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:146826909" variation complement(3287) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:144086616" variation complement(3303) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:139353948" variation complement(3321) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:145615584" STS 3350..3489 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /standard_name="RH78381" /db_xref="UniSTS:38153" variation complement(3389) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:149748563" STS 3439..3620 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /standard_name="STS-W15441" /db_xref="UniSTS:82348" variation complement(3490) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:374631187" variation complement(3539) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:139439518" polyA_signal 3636..3641 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" polyA_site 3657 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" variation complement(3999) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:181698971" variation complement(4024) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:190049858" variation complement(4029) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:112728642" variation complement(4146) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:185204780" variation complement(4154) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:111938473" variation complement(4156) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:374737737" variation complement(4187) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:79977262" STS 4392..4524 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /standard_name="D9S58" /db_xref="UniSTS:33358" variation complement(4434) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="g" /replace="t" /db_xref="dbSNP:191660985" variation complement(4435..4454) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="" /replace="tgtgtgtgtgtgtgtgtgtg" /db_xref="dbSNP:55719272" variation complement(4440) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="" /replace="tgtgtg" /replace="tgtgtgtgtg" /db_xref="dbSNP:56934484" variation complement(4485..4486) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="" /replace="tgtgtg" /db_xref="dbSNP:35223249" variation complement(4487..4488) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="" /replace="gtgtgt" /db_xref="dbSNP:10627956" variation complement(4488..4497) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="" /replace="gtgtgtgtgt" /db_xref="dbSNP:72205265" variation complement(4490..4497) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="" /replace="gtgtgtgt" /db_xref="dbSNP:368150329" variation complement(4496..4497) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="" /replace="gt" /db_xref="dbSNP:72107370" variation complement(4580) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:116604074" variation complement(4689) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:188762071" variation complement(4859) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:183693786" variation complement(4892) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:78043549" variation complement(4894) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="g" /replace="t" /db_xref="dbSNP:191559276" variation complement(4922..4923) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="" /replace="ca" /db_xref="dbSNP:201032332" variation complement(5024) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:368512455" variation complement(5157) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:139540788" variation complement(5169) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="" /replace="t" /db_xref="dbSNP:36043083" variation complement(5302) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:188734291" variation complement(5308) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="c" /db_xref="dbSNP:73525119" variation complement(5404) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:113826491" variation complement(5469) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:143204263" variation complement(5523) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="g" /replace="t" /db_xref="dbSNP:75255713" variation complement(5535) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="g" /replace="t" /db_xref="dbSNP:76421318" variation complement(5538) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="g" /replace="t" /db_xref="dbSNP:34740968" variation complement(5607) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:111487162" variation complement(5703..5704) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="" /replace="g" /db_xref="dbSNP:34907594" variation complement(5710) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:149641144" variation complement(5711) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:115259973" variation complement(5721..5722) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="" /replace="t" /db_xref="dbSNP:35111984" variation complement(5784) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:184231955" variation complement(5822) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="g" /db_xref="dbSNP:193101927" variation complement(5861) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:138126149" variation complement(5914) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="c" /db_xref="dbSNP:188503580" variation complement(5944) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="c" /db_xref="dbSNP:145645925" variation complement(5966) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:11537746" variation complement(5967) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:183499796" STS 5972..6094 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /standard_name="D9S1760" /db_xref="UniSTS:12586" STS 5975..6153 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /standard_name="D9S1693" /db_xref="UniSTS:65182" STS 5975..6147 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /standard_name="RH91146" /db_xref="UniSTS:88337" variation complement(5996) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="c" /replace="t" /db_xref="dbSNP:189997655" variation complement(6004) /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /replace="a" /replace="g" /db_xref="dbSNP:61744961" STS 6042..6154 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /standard_name="A009V09" /db_xref="UniSTS:77964" STS 6042..6154 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" /standard_name="G32870" /db_xref="UniSTS:117449" polyA_site 6199 /gene="PTPN3" /gene_synonym="PTP-H1; PTPH1" ORIGIN
ctctttcagctgctccatgctgctctcagctgtcttccccatgtatataccagctcacgcagagctgcagtgccacaaaagcagcttatagcaaagagagcgcatggcctatgtttcttgttatttaaaagctacatcataatccagtggcccttacgcagtgctcagcttcagtcagctacttggtattagcctgcggcagtggggctgccatcatttctacagagaagtaaactctaggcagccaagagcccccactcatcaggatcatggagtaaaggacatgcattgagaggcatcagcttcaacctggccgatccctgatgtgctttgtttgtgttttgttttattttttgaagggtgaacattctcaaaatttctttcaaaaggaaaaagttcttcatacatcagcgacagaaacaggctgaatccagggaacatattgtggccttcaacatgctgaattaccgatcttgcaaaaacttgtggaaatcctgtgttgagcaccatacgttctttcaggcaaagaagctactacctcaggaaaagaatgttctgtctcagtactggactatgggctctcggaacaccaaaaagtcggtaaataaccaatattgcaaaaaggtgattggcgggatggtgtggaacccagccatgcggagatccttatcagtggagcacttagaaaccaagagtctgccttctcgttcccctcccattactcccaactggcgaagtcctcggctccggcacgaaatccgaaagccacgccactcttctgcagataaccttgcaaatgaaatgacctacatcacggaaacggaagatgtattttacacgtacaagggctctctggcccctcaagacagcgattctgaagtttctcagaaccgaagcccgcaccaagagagtttatccgagaacaatccggcacaaagctacctgacccagaagtcatccagttctgtgtctccatcttcaaatgctccaggctcctgctcacctgacggcgttgatcagcagctcttagatgacttccacagggtgaccaaagggggctccaccgaggacgccagccagtactactgtgacaagaatgataatggtgacagctacttagtcttgatccgtatcacaccagatgaagatggaaaatttggatttaatcttaagggaggagtggatcaaaagatgcctcttgtggtatcaaggataaacccagagtcacctgcggacacctgcattcctaagctgaacgaaggggatcaaatcgtgttaatcaatggccgggacatctcagaacacacgcatgaccaagtggtgatgttcatcaaagccagccgggagtcccactcacgggagctggccctggtgatcaggaggagagctgtccgctcatttgctgacttcaagtctgaagatgaactgaaccagcttttccccgaagccattttccccatgtgtccggagggtggggacactttggagggatccatggcacagctaaagaagggcctcgaaagcgggacggtgctgatccagtttgagcaactctacagaaaaaagccaggtttggccatcacgtttgcaaagctgcctcaaaatttggacaaaaaccgatataaagatgtgctgccttatgacaccacccgggtattattgcagggaaatgaagattatattaatgcaagttacgtgaacatggaaattcctgctgctaaccttgtgaacaagtacatcgccactcaggggcccctgccgcatacctgtgcacagttttggcaggttgtctgggatcagaagttgtcactcattgtcatgttgacgactctcacagaacgagggcggaccaaatgtcaccagtactggccagatccccccgacgtcatgaaccacggcggctttcacatccagtgtcagtcagaggactgcaccatcgcctatgtgtcccgagaaatgctggtcacaaacacccagaccggggaagaacacacagtgacacatctccagtacgtcgcatggcctgaccacggtgtgcccgatgactcctccgactttctggaatttgtaaactatgtgaggtctctgagagtggacagcgagcccgtcctagttcactgcagtgctggaataggtcgaaccggtgtgttggtcactatggaaacagccatgtgcctaactgagaggaacctgcccatttacccactggatattgtccgaaaaatgcgagaccagcgcgccatgatggtgcagacatcaagccagtacaagtttgtgtgtgaagcgattcttcgtgtgtatgaagaaggtttagtccaaatgctggatcctagttaagacaactgtgaaaaagttcattcctctttcccaagggcatcctccttgaaagaggaggacagacctctctggaagcagcaagaggaaccagtagctgtgggaaaggaatgggcacctctgaacccaggcactttaaacttctatagaaaagatatcgtgtacataggaactggtgtagataagcatgcaattatggcatcatttaggcctgtatttctatggaaagatacaaaaaggatctcagtttggggcctgtcctaatgccttcttccctaacatcaccacacacacccctgtcggcatcctggagcaattgagaccggacacccacagagctgttgtcctcccagcaacaagatggtgtggttatcttgggtcatttggatgttttgtttgtttctgtgtgtcagactgtaagggctgagctttctgtgcttctaggtggagctggaacaattcagattcacccgccctgatgctaaggaaaccctgacgtatgtactagatggcagggcactgggggtcaggctgaaggctgagcaacacctctctgccctccctccctttgtcccatctcccagcgacttccaatattcatgtttctgagaattgtgtccctcttcaggttccctcttggtgcctaacctggattagtaatgtgcattcaggtgaattttcagctgaggctctgagaactggtactctcagtgtgttctggtcatcttgtggcttagttgtagaagcaggtgtgtctcttgcctctgcttgcctcctactgcacactcagcacccaggactggaatcaccgactactgaatctcctacatgtattgctgctacttcaagctcctccacttgaaaccttatgattttcccaaggggagatgggacagtgtcatctaaatattccgaatgtttggccttctgagaaaagagcttctagtaattgaaccatgggaaacccagcttctggagggttggccgtggggctgtgtacatgtgtgtgcccaggggtgagtgtttctcaggattcctaacgattcaaattaccgttgagtatatataaagaatgagtctctgtatggaagaacaaatgtgtgcattcacccccagtcacaatggtctccattgcatttcaaaggagaggatcagactatctgaatataaacacaatctgatgttaatttattctaagaacaccatcattttgattgtcctaaagaattctgcctttgtgaataccgtgttaaatttttttaaatttgtgacaggattgtagcaaattattatttaaggaaaataaattgtgtaaacatttaatgtggtatttttgaacagcggtttttatgtactcagaagaggaagtaaagccaggttcttaatggtatttatagaaaagatgttttcatattataatgcacataaatgaagccattttgatattcagcaaattcggtgccaattgaatagtttgctggtagcaagacggatgaagacctatatgggagattctttatctctagagctagcatatttacttgcatactttgtttcttttccacatggatattttactgctaaatggcagaggtgggagggagatgtcacacagtaccataaccccatattgaaaacaagaaaccaccagaaagtttgcagctaaggggcaggggattcagttcctacgcccactcagcactaactacttgcgggcctggttgcttagaagctctacctctctttcattatctgtaaaatagaaacaatacttaggactttagttggaacatgaggattgaataagatcacgctattcatgtgactttttatcggctagaacagcaacagacactgctgtgggtgagttacttagaaaagtttagttatcagtgattagcccaaaaacacatcagtcaaaaatagaatccactggatttttgtctctctttttagagacagggtctcactgtcgcccaggctggagtacagtggcatgatcattgttcactgcagcctcaaattcctgggctcaagcaatcctcgcacctcagcctcctgagtagccgggactataggcacatgccacctcacctggcttgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtagagacaggatcttgatgtgttgcctaggctggtctcaaactcctggcctcaagtgatcttcccacctcagcctccaaaactgttgggattataggcgtgagccactgtgcccagcctaactgggtttttatgagaggaaaatagaaaatgctcttctagaagagagagaacaagagcacaaaataatctggactcacaaaaattcagcaagctccaagaaagggggatggagggaacgctggcaaaaatttaaatgccattaggatatttagcaagttattactgtttggtaaaaatgcatcatcaccctgtgtgcaaaatgcttgcaaagtagtctaaatgtctttggagatgggtgttttactgcttttttccaaaaacaaattgtttattatggttgcagaaatgcagccattacggtcacataaatttctaaaaagcctaccaaaggttgcaagcagtcttctgccactgggcaggccagcagttcagacccagcgaggttgccaggaacaaatccaggaaatactgggaagaacaagacaagagaattacctaaaagagcaaacaattcaagtaaatcctgtagctattaccacttaaaatccgtagctcaagattcctgtttcaccaccttatacacttaagcaattatacttaagcctttttttagtcctaagtgaagaactacatcagaatcaggataagtattttgcctgggaaatttggctgcatatgaatggagaagacatttacatcctatgttctggcactttctgaaagatctaattaaacatgttgatgtgccaatttaatcaagatgagagatccctgctggtgtcaccctctagaacctgcacttggtgttttgactttccagaagaaaaaaatgcaactttggttagggggcagtggttggatcacacagttgtctttcgtttcctaccacagtaattcatatttaaatatgcttttagattagtgtggatactattgctgctgtgttgctacctgacctttttctggggggggtacctcagaaatgagcatttgagggcaagcgaaaaagccctcttcatcctccagaggcaacaaagaggcagcagaaatggggaaagattgtgagaggcagggcttgggtctagacctggacttaggcaagatatgttgccctcaaccctgagttttcttatatgtaaaaagggaaggttgggctggactagatgaggtcaagatttgccattctgggaggctgatattccagagaatcaaaattaatcctaaaccaaagctttatggctgctacagagacatgtcacatttctgagacttgtcaccaagagtttgtccctcagactttggcgctgttgaatgcaaagacaaggatggccaccttctggttcttgcctgttgtcctcagctgagagcagtctcggtaaaggtggcaaagattctgtgacctcagaccggggaccaaatgcttgggagtctgatggccgggctgggccaccattctcatagctctcattctgtttggagcaaccaaaggatttgtgtgaagttatttggaaaaggaccttaactgagcagtaatcttttttctgtatatttggaatgtttttcattctgacctgttctgtcagtgattctactgaaaaacaatttaatcaatataaaaatgttcaagctatgcaacactgtaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726): GeneID:5774 -> Molecular function: GO:0001784 [phosphotyrosine binding] evidence: IPI GeneID:5774 -> Molecular function: GO:0004725 [protein tyrosine phosphatase activity] evidence: IDA GeneID:5774 -> Molecular function: GO:0005515 [protein binding] evidence: IPI GeneID:5774 -> Molecular function: GO:0008092 [cytoskeletal protein binding] evidence: IEA GeneID:5774 -> Molecular function: GO:0051117 [ATPase binding] evidence: IPI GeneID:5774 -> Biological process: GO:0006470 [protein dephosphorylation] evidence: IDA GeneID:5774 -> Biological process: GO:0035335 [peptidyl-tyrosine dephosphorylation] evidence: IDA GeneID:5774 -> Biological process: GO:0035335 [peptidyl-tyrosine dephosphorylation] evidence: TAS GeneID:5774 -> Biological process: GO:0045930 [negative regulation of mitotic cell cycle] evidence: IDA GeneID:5774 -> Biological process: GO:0051045 [negative regulation of membrane protein ectodomain proteolysis] evidence: IMP GeneID:5774 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA GeneID:5774 -> Cellular component: GO:0005856 [cytoskeleton] evidence: IEA GeneID:5774 -> Cellular component: GO:0009898 [internal side of plasma membrane] evidence: IDA ANNOTATIONS from NCBI Entrez Gene (20130726): NP_001138843 -> EC 3.1.3.48
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