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2020-10-24 07:32:54, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001142446            8486 bp    mRNA    linear   PRI 07-JUL-2013
DEFINITION  Homo sapiens ankyrin 1, erythrocytic (ANK1), transcript variant 9,
            mRNA.
ACCESSION   NM_001142446
VERSION     NM_001142446.1  GI:215598573
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8486)
  AUTHORS   Harder,M.N., Ribel-Madsen,R., Justesen,J.M., Sparso,T.,
            Andersson,E.A., Grarup,N., Jorgensen,T., Linneberg,A., Hansen,T.
            and Pedersen,O.
  TITLE     Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with
            decreased beta-cell function whereas risk alleles near ANKRD55 and
            GRB14 associate with decreased insulin sensitivity in the Danish
            Inter99 cohort
  JOURNAL   J. Clin. Endocrinol. Metab. 98 (4), E801-E806 (2013)
   PUBMED   23457408
  REMARK    GeneRIF: ANK1 rs516946 confers impaired insulin release.
REFERENCE   2  (bases 1 to 8486)
  AUTHORS   Stefanovic,M., Puchulu-Campanella,E., Kodippili,G. and Low,P.S.
  TITLE     Oxygen regulates the band 3-ankyrin bridge in the human erythrocyte
            membrane
  JOURNAL   Biochem. J. 449 (1), 143-150 (2013)
   PUBMED   23013433
  REMARK    GeneRIF: The ankyrin-binding site on band 3 is located near the
            deoxygenated hemoglobin-binding site, therefore following
            deoxygenation ankyrin is displaced from band 3.
REFERENCE   3  (bases 1 to 8486)
  AUTHORS   Yocum,A.O., Steiner,L.A., Seidel,N.E., Cline,A.P., Rout,E.D.,
            Lin,J.Y., Wong,C., Garrett,L.J., Gallagher,P.G. and Bodine,D.M.
  TITLE     A tissue-specific chromatin loop activates the erythroid ankyrin-1
            promoter
  JOURNAL   Blood 120 (17), 3586-3593 (2012)
   PUBMED   22968456
  REMARK    GeneRIF: A tissue-specific chromatin loop brings NF-E2 and ANK1E
            into close proximity preventing gene silencing and mutagenesis
            leading to hereditary spherocytosis.
REFERENCE   4  (bases 1 to 8486)
  AUTHORS   Imamura M, Maeda S, Yamauchi T, Hara K, Yasuda K, Morizono T,
            Takahashi A, Horikoshi M, Nakamura M, Fujita H, Tsunoda T, Kubo M,
            Watada H, Maegawa H, Okada-Iwabu M, Iwabu M, Shojima N, Ohshige T,
            Omori S, Iwata M, Hirose H, Kaku K, Ito C, Tanaka Y, Tobe K,
            Kashiwagi A, Kawamori R, Kasuga M, Kamatani N, Nakamura Y and
            Kadowaki T.
  CONSRTM   Diabetes Genetics Replication and Meta-analysis (DIAGRAM)
            Consortium
  TITLE     A single-nucleotide polymorphism in ANK1 is associated with
            susceptibility to type 2 diabetes in Japanese populations
  JOURNAL   Hum. Mol. Genet. 21 (13), 3042-3049 (2012)
   PUBMED   22456796
  REMARK    GeneRIF: results indicate that the ANK1 locus is a new, common
            susceptibility locus for type 2 diabetes across different ethnic
            groups
REFERENCE   5  (bases 1 to 8486)
  AUTHORS   Lange,S., Perera,S., Teh,P. and Chen,J.
  TITLE     Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1
            (sAnk1.5) protein turnover
  JOURNAL   Mol. Biol. Cell 23 (13), 2490-2504 (2012)
   PUBMED   22573887
  REMARK    GeneRIF: The interaction of KCTD6 with ankyrin-1 may have
            implications beyond muscle for hereditary spherocytosis, as KCTD6
            is also present in erythrocytes, and erythrocyte ankyrin isoforms
            contain its mapped minimal binding site.
REFERENCE   6  (bases 1 to 8486)
  AUTHORS   Fujimoto,T., Lee,K., Miwa,S. and Ogawa,K.
  TITLE     Immunocytochemical localization of fodrin and ankyrin in bovine
            chromaffin cells in vitro
  JOURNAL   J. Histochem. Cytochem. 39 (11), 1485-1493 (1991)
   PUBMED   1833445
REFERENCE   7  (bases 1 to 8486)
  AUTHORS   Lux,S.E., John,K.M. and Bennett,V.
  TITLE     Analysis of cDNA for human erythrocyte ankyrin indicates a repeated
            structure with homology to tissue-differentiation and cell-cycle
            control proteins
  JOURNAL   Nature 344 (6261), 36-42 (1990)
   PUBMED   2137557
REFERENCE   8  (bases 1 to 8486)
  AUTHORS   Lambert,S., Yu,H., Prchal,J.T., Lawler,J., Ruff,P., Speicher,D.,
            Cheung,M.C., Kan,Y.W. and Palek,J.
  TITLE     cDNA sequence for human erythrocyte ankyrin
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 87 (5), 1730-1734 (1990)
   PUBMED   1689849
REFERENCE   9  (bases 1 to 8486)
  AUTHORS   Bennett,V.
  TITLE     Immunoreactive forms of human erythrocyte ankyrin are present in
            diverse cells and tissues
  JOURNAL   Nature 281 (5732), 597-599 (1979)
   PUBMED   492324
REFERENCE   10 (bases 1 to 8486)
  AUTHORS   Bennett,V. and Stenbuck,P.J.
  TITLE     The membrane attachment protein for spectrin is associated with
            band 3 in human erythrocyte membranes
  JOURNAL   Nature 280 (5722), 468-473 (1979)
   PUBMED   379653
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC027702.18, AB209418.1,
            X16609.1, AC113133.5 and N63745.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: Ankyrins are a family of proteins that link the integral
            membrane proteins to the underlying spectrin-actin cytoskeleton and
            play key roles in activities such as cell motility, activation,
            proliferation, contact and the maintenance of specialized membrane
            domains. Multiple isoforms of ankyrin with different affinities for
            various target proteins are expressed in a tissue-specific,
            developmentally regulated manner. Most ankyrins are typically
            composed of three structural domains: an amino-terminal domain
            containing multiple ankyrin repeats; a central region with a highly
            conserved spectrin binding domain; and a carboxy-terminal
            regulatory domain which is the least conserved and subject to
            variation. Ankyrin 1, the prototype of this family, was first
            discovered in the erythrocytes, but since has also been found in
            brain and muscles. Mutations in erythrocytic ankyrin 1 have been
            associated in approximately half of all patients with hereditary
            spherocytosis. Complex patterns of alternative splicing in the
            regulatory domain, giving rise to different isoforms of ankyrin 1
            have been described. Truncated muscle-specific isoforms of ankyrin
            1 resulting from usage of an alternate promoter have also been
            identified. [provided by RefSeq, Dec 2008].
            
            Transcript Variant: This variant (9) has an alternate upstream 5'
            exon, which includes an AUG start codon, and has an additional exon
            in the middle region, but lacks a segment in the 3' coding region,
            compared to variant 1. The reading frame is not affected and the
            resulting isoform (9) is the longest, which has a distinct
            N-terminus and an internal additional segment as well as lacks a
            segment in the C-terminal region, compared to isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB209418.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           ERS025081, ERS025082 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-93                AC027702.18        3683-3775
            94-3317             AB209418.1         94-3317
            3318-3628           X16609.1           2997-3307
            3629-4412           AB209418.1         3629-4412
            4413-4505           X16609.1           4092-4184
            4506-6379           AB209418.1         4506-6379
            6380-8442           AC113133.5         6296-8358           c
            8443-8486           N63745.1           1-44                c
FEATURES             Location/Qualifiers
     source          1..8486
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8p11.1"
     gene            1..8486
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="ankyrin 1, erythrocytic"
                     /db_xref="GeneID:286"
                     /db_xref="HGNC:492"
                     /db_xref="MIM:612641"
     exon            1..408
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    274..276
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="upstream in-frame stop codon"
     CDS             283..5976
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="isoform 9 is encoded by transcript variant 9;
                     ankyrin-R; ankyrin-1; ANK-1; erythrocyte ankyrin"
                     /codon_start=1
                     /product="ankyrin-1 isoform 9"
                     /protein_id="NP_001135918.1"
                     /db_xref="GI:215598574"
                     /db_xref="CCDS:CCDS47849.1"
                     /db_xref="GeneID:286"
                     /db_xref="HGNC:492"
                     /db_xref="MIM:612641"
                     /translation="
MAQAAKQLKKIKDIEAQALQEQKEKEESNRKRRNRSRDRKKKADAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDKHRMSFPETVDEILDVSEDEGTAHITIMGEELISFKAERRDSRDVDEEKELLDFVPKLDQVVESPAIPRIPCAMPETVVIRSEEQEQASKEYDEDSLIPSSPATETSDNISPVASPVHTGFLVSFMVDARGGSMRGSRHNGLRVVIPPRTCAAPTRITCRLVKPQKLSTPPPLAEEEGLASRIIALGPTGAQFLSPVIVEIPHFASHGRGDRELVVLRSENGSVWKEHRSRYGESYLDQILNGMDEELGSLEELEKKRVCRIITTDFPLYFVIMSRLCQDYDTIGPEGGSLKSKLVPLVQATFPENAVTKRVKLALQAQPVPDELVTKLLGNQATFSPIVTVEPRRRKFHRPIGLRIPLPPSWTDNPRDSGEGDTTSLRLLCSVIGGTDQAQWEDITGTTKLVYANECANFTTNVSARFWLSDCPRTAEAVNFATLLYKELTAVPYMAKFVIFAKMNDPREGRLRCYCMTDDKVDKTLEQHENFVEVARSRDIEVLEGMSLFAELSGNLVPVKKAAQQRSFHFQSFRENRLAMPVKVRDSSREPGGSLSFLRKAMKYEDTQHILCHLNITMPPCAKGSGAEDRRRTPTPLALRYSILSESTPGSLSGTEQAEMKMAVISEHLGLSWAELARELQFSVEDINRIRVENPNSLLEQSVALLNLWVIREGQNANMENLYTALQSIDRGEIVNMLEGSGRQSRNLKPDRRHTDRDYSLSPSQMNGYSSLQDELLSPASLGCALSSPLRADQYWNEVAVLDAIPLAATEHDTMLEMSDMQVWSAGLTPSLVTAEDSSLECSKAEDSDATGHEWKLEGALSEEPRGPELGSLELVEDDTVDSDATNGLIDLLEQEEGQRSEEKLPGSKRQDDATGAGQDSENEVSLVSGHQRGQARITHSPTVSQVTERSQDRLQDWDADGSIVSYLQDAAQGSWQEEVTQGPHSFQGTSTMTEGLEPGGSQEYEKVLVSVSEHTWTEQPEAESSQADRDRRQQGQEEQVQEAKNTFTQVVQGNEFQNIPGEQVTEEQFTDEQGNIVTKKIIRKVVRQIDLSSADAAQEHEEDHTSTPNP
"
     misc_feature    421..576
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (many copies); Region: Ank_4;
                     pfam13637"
                     /db_xref="CDD:205814"
     misc_feature    496..873
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:29261"
     misc_feature    526..798
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    910..1185
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    979..1356
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:29261"
     misc_feature    1108..1377
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    1306..1581
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    1375..1752
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:29261"
     misc_feature    1591..1752
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (many copies); Region: Ank_4;
                     pfam13637"
                     /db_xref="CDD:205814"
     misc_feature    1702..1962
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    1786..2148
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:29261"
     misc_feature    1900..2169
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    2068..2445
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:29261"
     misc_feature    2185..2346
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (many copies); Region: Ank_4;
                     pfam13637"
                     /db_xref="CDD:205814"
     misc_feature    2266..2643
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="ankyrin repeats;  ankyrin repeats mediate
                     protein-protein interactions in very diverse families of
                     proteins. The number of ANK repeats in a protein can range
                     from 2 to over 20 (ankyrins, for example). ANK repeats may
                     occur in combinations with other...; Region: ANK; cd00204"
                     /db_xref="CDD:29261"
     misc_feature    2296..2571
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:205076"
     misc_feature    2539..2703
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Ankyrin repeats (many copies); Region: Ank_5;
                     pfam13857"
                     /db_xref="CDD:206028"
     misc_feature    3136..3450
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Domain present in ZO-1 and Unc5-like netrin
                     receptors; Region: ZU5; smart00218"
                     /db_xref="CDD:128514"
     misc_feature    4606..4857
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /note="Death domain of Ankyrin-1; Region: Death_ank1;
                     cd08805"
                     /db_xref="CDD:176783"
     exon            409..510
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            511..609
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            610..708
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       696
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2304871"
     exon            709..807
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            808..993
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       870
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34173100"
     variation       978
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2304873"
     exon            994..1092
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            1093..1191
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            1192..1290
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            1291..1488
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            1489..1587
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            1588..1686
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            1687..1785
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            1786..1983
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       1887
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34387324"
     exon            1984..2082
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            2083..2181
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            2182..2379
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       2237
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2304877"
     exon            2380..2478
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       2454
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1137177"
     exon            2479..2577
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            2578..2676
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       2592
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:34194642"
     exon            2677..2769
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       2730
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2304880"
     exon            2770..2842
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            2843..2866
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            2867..2963
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       2900
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34523608"
     exon            2964..3042
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            3043..3140
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            3141..3365
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       3235
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:35797405"
     variation       3318
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:504574"
     variation       3351
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1137178"
     exon            3366..3520
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       3375
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34969689"
     exon            3521..3732
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       3629
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35213384"
     exon            3733..3937
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       3781
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:504465"
     variation       3891
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35964634"
     exon            3938..4034
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       3979
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:486770"
     exon            4035..4263
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            4264..4389
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            4390..4509
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            4510..4588
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            4589..4663
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            4664..4795
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       4790
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34664882"
     exon            4796..4942
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       4911
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:34265667"
     exon            4943..5501
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     variation       5041
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1060130"
     exon            5502..5799
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            5800..5883
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            5884..5949
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     exon            5950..8478
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /inference="alignment:Splign:1.39.8"
     STS             6095..6370
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /standard_name="SHGC-132081"
                     /db_xref="UniSTS:170634"
     STS             6106..6369
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /standard_name="RH69660"
                     /db_xref="UniSTS:24338"
     variation       6383
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201295961"
     STS             6522..6627
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /standard_name="GDB:178523"
                     /db_xref="UniSTS:66432"
     STS             6523..6708
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /standard_name="D8S2329"
                     /db_xref="UniSTS:31321"
     STS             6871..7203
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /standard_name="SHGC-12309"
                     /db_xref="UniSTS:21118"
     variation       7483..7484
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:517309"
     variation       8065
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:543817"
     STS             8093..8259
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
                     /standard_name="RH91316"
                     /db_xref="UniSTS:91775"
     polyA_signal    8456..8461
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
     polyA_site      8478
                     /gene="ANK1"
                     /gene_synonym="ANK; SPH1; SPH2"
ORIGIN      
gggaggcggcgggccctgcccagagcccgtcccgggcgccggcaagcgagctccggccgcggcggcagcgccatcccgggccgcgggcagccgcccctcgccctccgcgtccggaactgccttcgccttcccgcgaccccgcagcagccggccctcggggcgccacgaacgctgtcccctctgtggagcagagacccccttccccttcttagggggtgtcgcctcggggatcgctgagcgctaggggtccaggaggcggggacgggagcgccgtgacccgccatggctcaagcggccaaacagctgaagaaaatcaaagacatcgaggcgcaggccctccaggagcagaaggagaaggaggaatccaacaggaagcggagaaaccgctcccgtgaccgaaagaagaaggccgatgctgctaccagctttctgagagcagcaagatcaggtaacttggacaaagctttggatcacctgcggaatggggtagatattaacacctgtaaccagaatgggttgaatggcttgcatctggcttctaaggaaggccatgtgaaaatggtggttgaacttctgcacaaagaaatcattctagaaacgacaaccaagaaggggaacacggccctgcacatcgctgctctagccgggcaggatgaggtggtccgggagcttgtcaactatggagccaacgtcaacgcccagtcacagaaaggttttacacccctgtacatggcagcacaagagaaccacttggaagtggttaagtttttactggaaaatggagctaaccagaatgtagccacagaagacggcttcacgcctctggcggtagccctgcagcagggccatgagaacgtcgtcgcgcacctcatcaactacggcaccaaggggaaggtgcgcctcccggccctgcacatcgcggcccgcaacgacgacacgcgcacggctgcggtgctgctgcagaacgaccccaacccggacgtgctttccaagacgggattcacgcccctgcacattgcggctcactacgagaacctcaacgtggcccagttgctcctcaacagaggagccagcgtcaatttcacaccacagaacggcatcacgccactgcacatcgcctcccgcaggggcaacgtgatcatggtgcggctgctgctggatcggggagcccagatagaaaccaagaccaaggacgaattgacacctctccactgtgcagctcgaaatgggcacgtgcgaatctcagagatcctgctggaccacggggcaccaatccaagccaaaaccaagaacggcctgtccccaattcacatggcggctcagggagaccacctcgactgtgtccggctcctgttgcaatacgacgcagagatagacgacatcaccctggaccacctgaccccactccacgtggctgcccactgtggacaccacagggtggctaaggtccttctggataaaggggccaaacccaactccagagccctgaatggctttacccccttacacatcgcctgcaaaaagaaccacgtccgtgtcatggagctgctgctgaagacgggagcctcgatcgacgcggtcaccgagtctggcctgacacctctccacgtggcctccttcatggggcaccttcccatcgtgaagaacctcctgcagcggggggcgtcgcccaacgtctccaacgtgaaagtggagaccccgctacacatggcagccagagccgggcacacggaagtggccaaatatttactccagaacaaagccaaagtcaatgccaaggccaaggatgaccagaccccacttcactgtgcagctcgcatcggccacacaaacatggtgaagctcctgctggaaaataacgccaaccccaacctggccaccaccgccgggcacacccccctgcacattgcagcccgtgagggccatgtggaaacagtcctggcccttctggaaaaggaagcatcccaggcctgcatgaccaagaaaggatttacccctctgcacgtggcggccaagtacgggaaggtgcgggtggcagagctgctgctggagcgggacgcacacccgaatgctgccggaaaaaatggcctgacccccctgcacgtggccgtccatcacaacaacctggacatcgtcaagctgctgcttccccggggcggctccccgcacagccctgcctggaatggctacacccctttgcacatcgctgccaagcagaaccaggtggaggtggcccgtagtctgctgcagtatgggggctcagcaaacgccgagtcggtgcaaggtgtgacgccccttcacctggccgcccaggagggccacgcagagatggtggctctgctgctctcgaaacaagccaatggcaacctggggaacaagagcggactcactcccctccatctggtagcacaagaaggccacgttccagtggcagatgtgctgatcaaacacggcgtcatggtggacgccaccacccggatgggctacactcccctccatgtggccagtcactatggaaacatcaagctggtgaagtttctgctgcagcaccaggcagatgtcaatgccaagaccaagctaggatacagccccctgcaccaggcagcccagcagggacacacagacatcgtgactctgcttctgaaaaacggtgcttccccaaacgaggtcagctcggatggaaccacacctctggccatagccaagcgcttgggctacatttctgtcaccgacgtgctcaaggtcgtcacggatgaaaccagtttcgtgttagtcagtgataagcatcgaatgagtttccctgagacagttgatgagatcctggatgtctcggaagatgaaggaactgctcatataactataatgggggaagaactcatcagcttcaaggctgagaggcgggattccagggatgttgatgaagagaaggagctgctggattttgtgccgaagctagaccaagtggtggaatctccagccatccccaggattccctgtgccatgcctgagacagtggtgatcaggtcagaagagcaggagcaggcatctaaagagtatgatgaggactccctcatccccagcagcccggccaccgagacctcagacaacatcagcccggtggccagcccggtgcatacagggtttctggtgagcttcatggttgacgcccggggtggttccatgagaggaagtcgccacaacggcctgcgagtggtgatcccgccacggacgtgcgcagcgcccacccgcatcacctgccgcctggtcaagccccagaagctcagcacgccgcccccactggccgaggaggagggcctggccagcaggatcatagcactggggcccacgggggcacagttcctgagccctgtaatcgtggagatcccgcactttgcctcccatggccgtggagaccgcgagctcgtggttctgaggagcgaaaacggctccgtgtggaaggagcacaggagccgctatggagagagctacctggatcagatcctcaacgggatggacgaagagctggggagcctggaggagctagagaagaagagggtgtgccgaatcatcaccaccgacttcccgctgtacttcgtgatcatgtcacggctctgccaggactacgacaccatcggtcccgaagggggctccctgaagagcaagctggtgcccctggtacaggcaacgttcccggagaatgccgtcaccaagagagtgaagctggctctgcaggcccagcctgtcccggatgagcttgtcactaagctcctgggcaaccaggccacattcagccccattgtcaccgtggagccccggcgccggaagttccaccgccccattgggcttcggatcccactacctccttcctggaccgacaacccgagggacagcggggagggagacaccaccagcctgcgcctgctttgcagcgtcattggaggaacagaccaagcccagtgggaagacataacaggaaccaccaaacttgtatatgccaacgagtgcgccaacttcaccaccaatgtctctgccaggttttggctgtcggactgtcctcggactgctgaggctgtgaactttgccaccctgctgtacaaagagctcactgcagtgccctacatggccaaattcgtcatctttgccaagatgaatgacccccgagaggggcgcctgcgctgctactgcatgacagatgataaagtggacaagaccctggagcagcatgagaacttcgtggaggtggcccggagcagggacatagaggtgttggaaggaatgtccctgtttgcagaactctctgggaacctggtgcctgtgaagaaagctgcccagcagcggagcttccacttccagtcatttcgggagaaccgtctggccatgcctgtaaaggtgagggacagcagtcgagagccgggagggtccctgtcgtttctgcgcaaggcgatgaagtacgaggacacccagcacattctctgccacctgaacatcaccatgcccccctgcgccaagggaagtggagccgaagataggagaaggaccccgacgcccctggccctgcgatacagcattctcagtgagtccacaccaggttctctcagtgggacagagcaggcagagatgaagatggctgttatctcagagcacctcggtctcagctgggcagagttggcccgggagctgcagttcagtgtggaagacatcaacaggatccgagtggaaaatcccaactccctgttggagcagagtgtggccttgctgaacctctgggtcatccgtgaaggccaaaacgcaaacatggagaatctgtacacagccctgcagagcattgaccgtggcgagatcgtgaacatgctggagggttccggccgacagagccgcaacttgaagccagacaggcggcacaccgaccgcgactactcgctgtcaccctcccagatgaatggttactcctcactgcaggacgagctgctgtcccctgcctccctgggctgtgcactttcctctccgctacgtgcagaccagtactggaatgaggtggccgtcctagacgccatccccttggcggccacggagcatgacaccatgctggagatgtctgacatgcaggtgtggtctgcgggcctcacgccttctctggtcactgctgaggactcctctctggagtgtagcaaggctgaggactctgatgccacaggtcacgagtggaagttggagggggcactctcagaggaaccgcggggccccgagttgggctctctggaacttgtggaggacgacacagtggattcagatgccacaaatggccttatcgatttgcttgaacaggaggaaggtcagaggtcagaagagaagctgccaggttctaagaggcaggatgacgcgacaggtgcagggcaggactcagagaatgaagtgtctcttgtttcaggccatcagagggggcaagcccgaatcacacattcccccaccgtgagtcaggtgacggagaggagtcaggacagactgcaggactgggatgcagacggctcgattgtctcatacctgcaagatgctgcacaaggttcctggcaagaggaggtcacgcaaggtccacactcattccagggaacaagtaccatgactgaagggctagagcccggtggatctcaggagtacgagaaggtcctggtgtctgtaagtgagcacacgtggacagaacagcccgaggctgagagctcccaggccgacagggaccggaggcagcaaggccaagaagagcaggtgcaggaggccaagaacaccttcacccaagtggtgcaggggaatgagtttcagaatattccaggggagcaggtgacagaggagcaattcacggatgagcagggcaacattgtcaccaagaagatcattcgcaaggtggttcgacagatagacttgtccagcgccgatgccgcccaggagcacgaggaggatcacacctcgacacccaacccctgaaccccacacactctgccatgcacacaggaggagagctggacctgagggccaccgcagcggtgcacacattcctctgggctgacggcatgacctctgtaagggactcctgctagtcccctcttggcatgaatgactgactgtagacgcatgacctccaggcttcaatcctgcctcttgcaatgacagctgatctgtcggaaccaggacacaaaagcagcaagaagcggggagagagagggatagaaaacaagcgcaggagagcctgcgaacgcaaaagtgaatgagggctttttgtggctggggatgggttttggttttggggttttttttttaaattgttttgacttcgtacagggtactttttcccaacctcatctgtcagaaatccatgtgggcttcctggaaagaaaaaaaaaaaaaagaaaactaggcatgaaatcagtttaacaccttaatcttaagccatgtcctcatctgcccaccctccccaacccacatacctccattccacttgtgacaccccctcgactccctggtgacgctcctcccagatcgctctacatgacattcaggacacacacacacacacacacacaccactcgcctccactgaatctacacacagattttactgtgacttctgaagctgtatagactctgctgtggataaattggaattttttatgttgtctctctctctgccaatttcaatacgaatcatcttccaatggaaaatcattaccttgaagagtgcattcggggttccttgtgttagggacttaagaatctgaggcgaggacccccaggcttacctgtaggactcaaagggagccaggaccccatctgaaagggtctcctctctcagttgggggacaggccggtggctgacccaggattgcaccagcatgtccatagagaagaggttttctatgtcttcaagcactatatcatagtccgtgttcaaagtgtaaactgtacagtaatcagccttgtgtatatgaaaaacaataaatactatgcaaaccaatagaaacatttagcagtacgtacagagcctgacagcgcagctcctgaggacttctgcggctgcaggagaaggagctgtggcctgtctttcagtgaaagaggaaggaaaggagtagggctagtgaatgtatctgccaggtcttagaagtcaggaccacccagggtctcccagagtgaacttggtgctctaagtccaggcagcctgcaggctggggaccctgggtgcaggtgccaggctcgaggctgttccctgtcctgcctcagtgcctcccctctgcccagcccctgtggcctcttggagaggcgagccagggggctccccggaccgcatggccggtgagagtagagtcggaggcggagagcctggacgcccagaggccggggccaggctctgggtcaaggcaggaaggagacagacagctggcagttcctcgcctcggtgccatcagggaggagccttaagttccactagagcctccggcccagggaggccagaatcagcacaatcccggccccgccctcgcggcgggcgcccccagggccaggagagagagacagggctggctcctctcgcccctggagccgcggtgtggacggcccggccccgtccgccccgccgctctgcgggagtgtcctcgggacacacttaaaccttccaagtagcacagaagccccctccacgtcagaggccccctggccgcggggcctgtgagcggagaggggccctgcttcccacacaaatccgccccggtgcacccccggccaggcaggccccggggcggcctaggcgccttgtcggccgggggtggggctgcttttgcttcctttagaggggcgggcagggagaggaagctctagctccgggcctgagtttccccgaggctgcgtcggaggagctgcagggcgagcccggacggctgccgtctccgccagaggccaccccggcccggcctccagggcgcagaggcgcccccctccatcctcccccatcccgggggccacggcaggggggccgcacagcgcggctgggaccgattcggtgacggcccaaggaagctgggctcagggctcgcctctcccgcctcgatcctgcaccttcctctcccaggtcgctgctgcagccaacccagtagcccccttagcgcccccgcggaccccgcagctccagactccgctttggcacctctgctccggctggcatggctgcacgctccggctgctagtaggagccgttaggggaggagtttggggtctccacacgatgcctagagaatgctgcagtctgcacattagacgctttttagaagttttgaaattaccttgatttttttaattgttatgaaaatggatcttttcttgactctcccacatgctctgttatgggagagaatcccctaccctactctgatgtatagaccattctcccttcaccagccgaaccaatgtcaaaattaataaagaaatggactaatggcaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:286 -> Molecular function: GO:0005198 [structural molecule activity] evidence: NAS
            GeneID:286 -> Molecular function: GO:0005200 [structural constituent of cytoskeleton] evidence: TAS
            GeneID:286 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:286 -> Molecular function: GO:0008093 [cytoskeletal adaptor activity] evidence: IDA
            GeneID:286 -> Molecular function: GO:0008093 [cytoskeletal adaptor activity] evidence: TAS
            GeneID:286 -> Molecular function: GO:0019899 [enzyme binding] evidence: IPI
            GeneID:286 -> Molecular function: GO:0019899 [enzyme binding] evidence: TAS
            GeneID:286 -> Molecular function: GO:0030507 [spectrin binding] evidence: IDA
            GeneID:286 -> Molecular function: GO:0030507 [spectrin binding] evidence: IPI
            GeneID:286 -> Molecular function: GO:0030507 [spectrin binding] evidence: NAS
            GeneID:286 -> Molecular function: GO:0051117 [ATPase binding] evidence: IPI
            GeneID:286 -> Biological process: GO:0006779 [porphyrin-containing compound biosynthetic process] evidence: IEA
            GeneID:286 -> Biological process: GO:0006887 [exocytosis] evidence: NAS
            GeneID:286 -> Biological process: GO:0006888 [ER to Golgi vesicle-mediated transport] evidence: IDA
            GeneID:286 -> Biological process: GO:0007010 [cytoskeleton organization] evidence: NAS
            GeneID:286 -> Biological process: GO:0007165 [signal transduction] evidence: IEA
            GeneID:286 -> Biological process: GO:0007411 [axon guidance] evidence: TAS
            GeneID:286 -> Biological process: GO:0015672 [monovalent inorganic cation transport] evidence: IEA
            GeneID:286 -> Biological process: GO:0045199 [maintenance of epithelial cell apical/basal polarity] evidence: TAS
            GeneID:286 -> Biological process: GO:0048821 [erythrocyte development] evidence: IEA
            GeneID:286 -> Biological process: GO:0072661 [protein targeting to plasma membrane] evidence: IMP
            GeneID:286 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:286 -> Cellular component: GO:0005856 [cytoskeleton] evidence: NAS
            GeneID:286 -> Cellular component: GO:0005886 [plasma membrane] evidence: IDA
            GeneID:286 -> Cellular component: GO:0005886 [plasma membrane] evidence: NAS
            GeneID:286 -> Cellular component: GO:0014731 [spectrin-associated cytoskeleton] evidence: IDA
            GeneID:286 -> Cellular component: GO:0016323 [basolateral plasma membrane] evidence: NAS
            GeneID:286 -> Cellular component: GO:0016529 [sarcoplasmic reticulum] evidence: IEA
            GeneID:286 -> Cellular component: GO:0030863 [cortical cytoskeleton] evidence: IEA
            GeneID:286 -> Cellular component: GO:0031430 [M band] evidence: IEA

by @meso_cacase at DBCLS
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