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2020-10-24 06:13:25, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001137667            6782 bp    mRNA    linear   PRI 07-JUL-2013
DEFINITION  Homo sapiens caspase 8 associated protein 2 (CASP8AP2), transcript
            variant 2, mRNA.
ACCESSION   NM_001137667
VERSION     NM_001137667.1  GI:212549781
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6782)
  AUTHORS   Yang,X.C., Sabath,I., Debski,J., Kaus-Drobek,M., Dadlez,M.,
            Marzluff,W.F. and Dominski,Z.
  TITLE     A complex containing the CPSF73 endonuclease and other
            polyadenylation factors associates with U7 snRNP and is recruited
            to histone pre-mRNA for 3'-end processing
  JOURNAL   Mol. Cell. Biol. 33 (1), 28-37 (2013)
   PUBMED   23071092
  REMARK    GeneRIF: FLASH/Lsm11 complex bind a unique combination of
            polyadenylation factors
REFERENCE   2  (bases 1 to 6782)
  AUTHORS   Lee,K.D., Pai,M.Y., Hsu,C.C., Chen,C.C., Chen,Y.L., Chu,P.Y.,
            Lee,C.H., Chen,L.T., Chang,J.Y., Huang,T.H., Hsiao,S.H. and
            Leu,Y.W.
  TITLE     Targeted Casp8AP2 methylation increases drug resistance in
            mesenchymal stem cells and cancer cells
  JOURNAL   Biochem. Biophys. Res. Commun. 422 (4), 578-585 (2012)
   PUBMED   22595458
  REMARK    GeneRIF: These data demonstrate that methylation within the
            Casp8AP2 promoter correlates with the development of drug
            resistance and might serve as a biomarker and treatment target for
            drug resistance in cancer cells.
REFERENCE   3  (bases 1 to 6782)
  AUTHORS   De Cola,A., Bongiorno-Borbone,L., Bianchi,E., Barcaroli,D.,
            Carletti,E., Knight,R.A., Di Ilio,C., Melino,G., Sette,C. and De
            Laurenzi,V.
  TITLE     FLASH is essential during early embryogenesis and cooperates with
            p73 to regulate histone gene transcription
  JOURNAL   Oncogene 31 (5), 573-582 (2012)
   PUBMED   21725362
  REMARK    GeneRIF: Data show that show that the transcription factor p73
            binds to Flice-Associated Huge Protein (FLASH) and is part of the
            complex that regulates histone gene transcription.
REFERENCE   4  (bases 1 to 6782)
  AUTHORS   Chen,S., Evans,H.G. and Evans,D.R.
  TITLE     FLASH knockdown sensitizes cells to Fas-mediated apoptosis via
            down-regulation of the anti-apoptotic proteins, MCL-1 and Cflip
            short
  JOURNAL   PLoS ONE 7 (3), E32971 (2012)
   PUBMED   22427918
  REMARK    GeneRIF: FLASH knockdown in HT1080 mutant cells defective in p53
            did not significantly accelerate Fas mediated apoptosis indicating
            that the effect was dependent on functional p53.
REFERENCE   5  (bases 1 to 6782)
  AUTHORS   Hummon,A.B., Pitt,J.J., Camps,J., Emons,G., Skube,S.B., Huppi,K.,
            Jones,T.L., Beissbarth,T., Kramer,F., Grade,M.,
            Difilippantonio,M.J., Ried,T. and Caplen,N.J.
  TITLE     Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional
            deregulation of the replication-dependent histone genes and
            extensive effects on the transcriptome of colorectal cancer cells
  JOURNAL   Mol. Cancer 11, 1 (2012)
   PUBMED   22216762
  REMARK    GeneRIF: This study further defines the role CASP8AP2/FLASH plays
            in the regulating expression of the replication-dependent histones
            and shows that its LOF results in broad and reproducible effects on
            the transcriptome of colorectal cancer cells
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6782)
  AUTHORS   Jun,J.I., Chung,C.W., Lee,H.J., Pyo,J.O., Lee,K.N., Kim,N.S.,
            Kim,Y.S., Yoo,H.S., Lee,T.H., Kim,E. and Jung,Y.K.
  TITLE     Role of FLASH in caspase-8-mediated activation of NF-kappaB:
            dominant-negative function of FLASH mutant in NF-kappaB signaling
            pathway
  JOURNAL   Oncogene 24 (4), 688-696 (2005)
   PUBMED   15592525
  REMARK    GeneRIF: endogenous caspase-8 mediates tumor necrosis
            factor-alpha-induced activation of NF-kappaB via FLASH
REFERENCE   7  (bases 1 to 6782)
  AUTHORS   Kino,T. and Chrousos,G.P.
  TITLE     Tumor necrosis factor alpha receptor- and Fas-associated FLASH
            inhibit transcriptional activity of the glucocorticoid receptor by
            binding to and interfering with its interaction with p160 type
            nuclear receptor coactivators
  JOURNAL   J. Biol. Chem. 278 (5), 3023-3029 (2003)
   PUBMED   12477726
REFERENCE   8  (bases 1 to 6782)
  AUTHORS   Choi,Y.H., Kim,K.B., Kim,H.H., Hong,G.S., Kwon,Y.K., Chung,C.W.,
            Park,Y.M., Shen,Z.J., Kim,B.J., Lee,S.Y. and Jung,Y.K.
  TITLE     FLASH coordinates NF-kappa B activity via TRAF2
  JOURNAL   J. Biol. Chem. 276 (27), 25073-25077 (2001)
   PUBMED   11340079
REFERENCE   9  (bases 1 to 6782)
  AUTHORS   Koonin,E.V., Aravind,L., Hofmann,K., Tschopp,J. and Dixit,V.M.
  TITLE     Apoptosis. Searching for FLASH domains
  JOURNAL   Nature 401 (6754), 662 (1999)
   PUBMED   10537104
REFERENCE   10 (bases 1 to 6782)
  AUTHORS   Imai,Y., Kimura,T., Murakami,A., Yajima,N., Sakamaki,K. and
            Yonehara,S.
  TITLE     The CED-4-homologous protein FLASH is involved in Fas-mediated
            activation of caspase-8 during apoptosis
  JOURNAL   Nature 398 (6730), 777-785 (1999)
   PUBMED   10235259
  REMARK    Erratum:[Nature 1999 Jul 1;400(6739):89]
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BP363682.1, BC132828.1 and
            AF154415.1.
            
            Summary: This protein is highly similar to FLASH, a mouse apoptotic
            protein identified by its interaction with the death-effector
            domain (DED) of caspase 8. Studies of FLASH protein suggested that
            this protein may be a component of the death-inducing signaling
            complex that includes Fas receptor, Fas-binding adapter FADD, and
            caspase 8, and plays a regulatory role in Fas-mediated apoptosis.
            Alternative splicing results in multiple transcript variants
            encoding the same protein.[provided by RefSeq, Nov 2008].
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC132828.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           ERS025082, ERS025083 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-153               BP363682.1         1-153
            154-6672            BC132828.1         1-6519
            6673-6782           AF154415.1         6673-6782
FEATURES             Location/Qualifiers
     source          1..6782
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q15"
     gene            1..6782
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /note="caspase 8 associated protein 2"
                     /db_xref="GeneID:9994"
                     /db_xref="HGNC:1510"
                     /db_xref="MIM:606880"
     variation       4
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375731771"
     variation       10
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368340936"
     variation       24
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:183190155"
     variation       46
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:150333903"
     variation       65
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:73752810"
     variation       70
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:137975335"
     variation       92
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143660157"
     variation       105
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:367700022"
     misc_feature    173..175
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /note="upstream in-frame stop codon"
     variation       188
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:371341158"
     CDS             197..6145
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /note="FLICE associated huge; CASP8 associated protein 2;
                     FLICE-associated huge protein; human FLASH; FLASH homolog
                     RIP25"
                     /codon_start=1
                     /product="CASP8-associated protein 2"
                     /protein_id="NP_001131139.1"
                     /db_xref="GI:212549782"
                     /db_xref="GeneID:9994"
                     /db_xref="HGNC:1510"
                     /db_xref="MIM:606880"
                     /translation="
MAADDDNGDGTSLFDVFSASPLKNNDEGSLDIYAGLDSAVSDSASKSCVPSRNCLDLYEEILTEEGTAKEATYNDLQVEYGKCQLQMKELMKKFKEIQTQNFSLINENQSLKKNISALIKTARVEINRKDEEISNLHQRLSEFPHFRNNHKTARTFDTVKTKDLKSRSPHLDDCSKTDHRAKSDVSKDVHHSTSLPNLEKEGKPHSDKRSTSHLPTSVEKHCTNGVWSRSHYQVGEGSSNEDSRRGRKDIRHSQFNRGTERVRKDLSTGCGDGEPRILEASQRLQGHPEKYGKGEPKTESKSSKFKSNSDSDYKGERINSSWEKETPGERSHSRVDSQSDKKLERQSERSQNINRKEVKSQDKEERKVDQKPKSVVKDQDHWRRSERASLPHSKNEITFSHNSSKYHLEERRGWEDCKRDKSVNSHSFQDGRCPSSLSNSRTHKNIDSKEVDAMHQWENTPLKAERHRTEDKRKREQESKEENRHIRNEKRVPTEHLQKTNKETKKTTTDLKKQNEPKTDKGEVLDNGVSEGADNKELAMKAESGPNETKNKDLKLSFMKKLNLTLSPAKKQPVSQDNQHKITDIPKSSGVCDSESSMQVKTVAYVPSISEHILGEAAVSEHTMGETKSTLLEPKVALLAVTEPRIGISETNKEDENSLLVRSVDNTMHCEEPICGTETSFPSPMEIQQTESLFPSTGMKQTINNGRAAAPVVMDVLQTDVSQNFGLELDTKRNDNSDYCGISEGMEMKVALSTTVSETTESILQPSIEEADILPIMLSEDNNPKFEPSVIVTPLVESKSCHLEPCLPKETLDSSLQQTELMDHRMATGETNSVYHDDDNSVLSIDLNHLRPIPEAISPLNSPVRPVAKVLRNESPPQVPVYNNSHKDVFLPNSAHSTSKSQSDLNKENQKPIYKSDKCTEADTCKNSPLDELEEGEIRSDSETSKPQESFEKNSKRRVSADVRKSKTIPRRGKSTVCLDKDSRKTHVRIHQTNNKWNKRPDKSSRSSKTEKKDKVMSTSSLEKIVPIIAVPSSEQEIMHMLRMIRKHVRKNYMKFKAKFSLIQFHRIIESAILSFTSLIKHLNLHKISKSVTTLQKNLCDIIESKLKQVKKNGIVDRLFEQQLPDMKKKLWKFVDDQLDYLFAKLKKILVCDSKSFGRDSDEGKLEKTSKQNAQYSNSQKRSVDNSNRELLKEKLSKSEDPVHYKSLVGCKKSEENYQDQNNSSINTVKHDIKKNFNICFDNIKNSQSEERSLEVHCPSTPKSEKNEGSSIEDAQTSQHATLKPERSFEILTEQQASSLTFNLVSDAQMGEIFKSLLQGSDLLDSSVNCTEKSEWELKTPEKQLLETLKCESIPACTTEELVSGVASPCPKMISDDNWSLLSSEKGPSLSSGLSLPVHPDVLDESCMFEVSTNLPLSKDNVCSVEKSKPCVSSILLEDLAVSLTVPSPLKSDGHLSFLKPDMSSSSTPEEVISAHFSEDALLEEEDASEQDIHLALESDNSSSKSSCSSSWTSRSVAPGFQYHPNLPMHAVIMEKSNDHFIVKIRRATPSTSSGLKQSMMPDELLTSLPRHGKEADEGPEKEYISCQNTVFKSVEELENSNKNVDGSKSTHEEQSSMIQTQVPDIYEFLKDASDKMGHSDEVADECFKLHQVWETKVPESIEELPSMEEISHSVGEHLPNTYVDLTKDPVTETKNLGEFIEVTVLHIDQLGCSGGNLNQSAQILDNSLQADTVGAFIDLTQDASSEAKSEGNHPALAVEDLGCGVIQVDEDNCKEEKAQVANRPLKCIVEETYIDLTTESPSSCEVKKDELKSEPGSNCDNSELPGTLHNSHKKRRNISDLNHPHKKQRKETDLTNKEKTKKPTQDSCENTEAHQKKASKKKAPPVTKDPSSLKATPGIKDSSAALATSTSLSAKNVIKKKGEIIILWTRNDDREILLECQKRGPSFKTFAYLAAKLDKNPNQVSERFQQLMKLFEKSKCR
"
     misc_feature    200..202
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="N-acetylalanine; propagated from
                     UniProtKB/Swiss-Prot (Q9UKL3.1); acetylation site"
     misc_feature    254..256
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q9UKL3.1); phosphorylation site"
     misc_feature    5243..5257
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UKL3.1);
                     Region: SUMO interaction motif 1 (SIM), mediates the
                     binding to polysumoylated substrates (By similarity)"
     misc_feature    5321..6142
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UKL3.1);
                     Region: NCOA2-binding"
     misc_feature    5405..5419
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UKL3.1);
                     Region: SUMO interaction motif 2 (SIM), mediates the
                     binding to polysumoylated substrates (By similarity)"
     misc_feature    5576..5590
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9UKL3.1);
                     Region: SUMO interaction motif 3 (SIM), mediates the
                     binding to polysumoylated substrates (By similarity)"
     misc_feature    5942..6136
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /note="Caspase 8-associated protein 2 myb-like domain;
                     Region: CASP8AP2; cd12202"
                     /db_xref="CDD:213401"
     variation       205
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:371635635"
     variation       244
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:35891026"
     variation       247
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376288172"
     variation       272
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377117590"
     variation       341
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:138471825"
     variation       358
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374871939"
     variation       370
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369309364"
     variation       475
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369328"
     variation       544
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375845338"
     variation       547
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:370454326"
     variation       691
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191794738"
     variation       707
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375746744"
     variation       713
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371046529"
     variation       788
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:79485882"
     variation       828
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199979891"
     variation       849
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:115337779"
     variation       851
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374867724"
     variation       859
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182729426"
     variation       868
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372111972"
     variation       882
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:377049861"
     variation       905
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:368353175"
     variation       906
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202238236"
     variation       924
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376835324"
     variation       941
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369918159"
     variation       966
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371653827"
     variation       967
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:116832209"
     variation       984
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200917530"
     variation       1006
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201596073"
     variation       1008
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369118984"
     variation       1066
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3734656"
     variation       1067
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:376169756"
     variation       1068
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369927994"
     variation       1090
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373400557"
     variation       1105
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377422956"
     variation       1175
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200248550"
     variation       1197
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374722055"
     variation       1225
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:9444715"
     variation       1243
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370574439"
     variation       1253
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375447849"
     variation       1301
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368346657"
     variation       1312
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:372317117"
     variation       1360
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374277382"
     variation       1456
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:75673851"
     variation       1500
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:74395498"
     variation       1533
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:187658864"
     variation       1538
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372268202"
     variation       1539
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374708182"
     variation       1548
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202104748"
     variation       1552
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34701151"
     variation       1568
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201785439"
     variation       1627
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:192787612"
     variation       1720
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369303003"
     variation       1746
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200323558"
     variation       1802
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376777596"
     variation       1808
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370049023"
     variation       1814
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374581994"
     variation       1864
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377395999"
     variation       1874
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370348129"
     variation       1912
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370445193"
     variation       1914
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200220681"
     variation       1936
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377095494"
     variation       1986
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370562618"
     variation       2064
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:375044202"
     variation       2066
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368459977"
     variation       2112
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:372157483"
     variation       2134
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374796247"
     variation       2135
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139622677"
     variation       2159
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:367672377"
     variation       2161
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371194420"
     variation       2176
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375013992"
     variation       2182
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368221756"
     variation       2198
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201489639"
     variation       2218
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376398807"
     variation       2251
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369747236"
     variation       2266
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374435750"
     variation       2308
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373095386"
     variation       2332
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:185478571"
     variation       2346
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369938492"
     variation       2399
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199531988"
     variation       2443
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:376213760"
     variation       2463
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:370683344"
     variation       2493
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:189475790"
     variation       2568
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:118038939"
     variation       2580
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:377330360"
     variation       2587
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3799895"
     variation       2593
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370853193"
     variation       2603
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374310883"
     variation       2628
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373335807"
     variation       2719
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191911199"
     variation       2728
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201271265"
     variation       2734
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368553205"
     variation       2760
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371069501"
     variation       2799
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:184335133"
     variation       2819
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201494268"
     variation       2873
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:202224866"
     variation       2913
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:137945652"
     variation       2946
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:199818755"
     variation       3050
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201306147"
     variation       3065
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:368026528"
     variation       3085..3086
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:34572105"
     variation       3111
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:117850701"
     variation       3135
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149473817"
     variation       3152
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201974982"
     variation       3156
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376299045"
     variation       3175
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369795421"
     variation       3192
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:114897724"
     variation       3258
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:375785540"
     variation       3324
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369132664"
     variation       3355
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370730058"
     STS             3584..3740
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /standard_name="STS-H50583"
                     /db_xref="UniSTS:2284"
     variation       3599
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:373329038"
     variation       3636
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1064002"
     variation       3664
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:143076875"
     variation       3701
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:182864217"
     variation       3828
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41273333"
     variation       3854
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:116614248"
     variation       3908
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201597048"
     variation       3910
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199918891"
     variation       3912
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:73752819"
     variation       3915
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:201506096"
     variation       3943
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376295745"
     variation       3950
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200866261"
     variation       3951
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374748337"
     variation       3967
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369576046"
     variation       3997
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367664392"
     variation       4010
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370073401"
     variation       4012
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374343288"
     variation       4040
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:186180164"
     variation       4047
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148256815"
     variation       4056
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375610839"
     variation       4063
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:141249173"
     variation       4089
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372787304"
     variation       4090
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375991831"
     variation       4133
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370120781"
     variation       4153
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:371257885"
     variation       4159
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374774067"
     variation       4212
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:369180336"
     variation       4218
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:78396072"
     variation       4249
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147437828"
     variation       4256
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376211225"
     variation       4333
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369714914"
     variation       4366
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373655186"
     variation       4501
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376852526"
     variation       4583
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139736386"
     variation       4584
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143016644"
     variation       4588
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371559146"
     variation       4622
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:190118214"
     variation       4734
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:75601500"
     variation       4789
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:60966143"
     variation       4837
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200433993"
     variation       4894..4911
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace=""
                     /replace="gacatctttgcccagaca"
                     /db_xref="dbSNP:202116886"
     variation       4899
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:202101805"
     variation       4901
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200213073"
     variation       4907
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201189413"
     variation       4910
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202111256"
     variation       4912
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:199694900"
     variation       4913
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200862023"
     variation       4914
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201534830"
     variation       4915
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:199515704"
     variation       5034
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139983441"
     variation       5063
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:150022229"
     variation       5087
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:369757511"
     variation       5113
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368260598"
     variation       5131
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371881005"
     variation       5144
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:111766212"
     variation       5163
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:375182927"
     variation       5171
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3799896"
     variation       5174
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:372893351"
     variation       5231..5232
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:34373654"
     variation       5238
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374695928"
     variation       5246
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200556402"
     variation       5318
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369072391"
     variation       5319
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371594163"
     variation       5334
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199714955"
     variation       5338
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369451328"
     variation       5356
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:200853389"
     variation       5379
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:377357235"
     variation       5400
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369858460"
     variation       5402
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:117650507"
     variation       5422
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377396142"
     variation       5433
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370442854"
     variation       5494
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:374893112"
     variation       5500
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377482246"
     variation       5505
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:73752820"
     variation       5515
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374232968"
     variation       5522
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368605777"
     variation       5532
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371085535"
     variation       5563
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374618973"
     variation       5596
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:368658707"
     STS             5598..5835
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /standard_name="SHGC-52865"
                     /db_xref="UniSTS:38874"
     variation       5617
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:371166110"
     variation       5621
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200564116"
     variation       5711
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201549866"
     variation       5714
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:200157861"
     variation       5802
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1062121"
     variation       5847
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199771380"
     variation       5873
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182937785"
     variation       5894
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:367942163"
     variation       5928
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372229978"
     variation       6011
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369939894"
     variation       6027
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200753477"
     variation       6061
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:374433157"
     variation       6146
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370975833"
     variation       6171
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376095529"
     variation       6181
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367794675"
     variation       6218
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:11752373"
     variation       6285
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368628751"
     variation       6293
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:112756481"
     variation       6331
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:371344448"
     variation       6490
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:372563597"
     variation       6510
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:370145460"
     STS             6539..6680
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /standard_name="RH47433"
                     /db_xref="UniSTS:49695"
     variation       6620
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142161883"
     variation       6687..6688
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
                     /replace=""
                     /replace="tt"
                     /db_xref="dbSNP:71864478"
     polyA_signal    6746..6751
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
     polyA_site      6772
                     /gene="CASP8AP2"
                     /gene_synonym="CED-4; FLASH; RIP25"
ORIGIN      
aaaggaaccgggttgtcttgggccgggcagggcgggtaagttgtcgtaggggcccggtccgtgagggactgctaaggaagaggctgcatggcgcggtagtcccccgagtggaggtcggctgcccctgggaaaccagagagtcggagggagtccatctggagcggccaagtggtgactctcaaaaggaaataggatcatggcagcagatgatgacaatggtgatggaacaagtttatttgatgtcttttctgcttctcctcttaagaacaatgatgaaggctcactggacatatacgctgggttggacagtgctgtttctgacagcgcttccaaatcctgtgtaccatcaagaaattgtttggacttatatgaagagatcctgactgaagaaggaactgcaaaggaggcaacatataatgatttgcaagtagaatatggaaaatgtcaactacaaatgaaagagctgatgaaaaaatttaaagaaatacagacacagaatttcagcttaataaacgaaaaccagtctcttaagaagaatatttcagcacttatcaaaactgccagagtggaaataaaccgcaaggatgaagaaataagtaatcttcaccaaagattgtctgagtttccacattttcgaaataatcataaaactgcaaggacatttgatacagttaaaacaaaagatcttaaatctagatctccacatttggatgattgttcaaagactgatcacagagctaaaagtgatgtttctaaagatgtacatcatagcacttcactgccaaatctggaaaaggaaggaaaaccacattctgataaaaggagtacttcacatttacctacatctgttgagaaacactgcactaatggtgtttggtcacgttctcattatcaggttggcgagggtagctcaaatgaggatagtagaagaggaagaaaagatattagacatagccagtttaacagaggaactgaaagagtacgaaaagacttaagtactggctgtggtgatggtgaaccaaggatattggaggctagtcaaaggctacaaggacatcctgagaaatatggtaaaggtgaaccaaagactgaaagcaaaagttcgaagtttaaaagtaactcagattctgactataaaggtgaacgcattaactcttcttgggagaaagagacccctggagaaaggtcacacagtcgagtagactctcaaagtgacaaaaaactagaaagacaaagtgaaagatcacaaaatataaataggaaagaagttaaatcacaagacaaagaagaaagaaaagttgatcaaaaacctaaatcagtagtaaaggaccaagatcactggagaagatctgaacgagcatcacttcctcattccaagaatgaaataacattttctcataattcaagtaaataccatctagaagagagaagaggatgggaagattgtaaaagagacaagagtgtaaacagtcatagttttcaagatggaagatgtccatcttctctttcaaacagtagaactcacaaaaacattgactctaaggaagttgatgccatgcatcagtgggaaaatacacctttaaaagcagaaagacatagaactgaagataagaggaaaagagaacaagaaagcaaagaagaaaataggcatattagaaatgaaaaaagagtacctacagaacatttgcagaagactaataaggaaactaagaaaaccactactgatttaaagaaacagaatgaaccaaagactgataagggagaagtccttgataatggtgtttctgaaggagcagataataaagagcttgcaatgaaagctgagagtggtccaaatgaaacaaaaaacaaggacctaaaattgagttttatgaaaaaattgaacttaactctttctcctgctaaaaagcaacctgtttcccaggataatcagcataaaataactgatattcccaagtccagtggtgtatgtgattcagagtcttcaatgcaagttaaaacagtggcatatgttccctccataagtgaacatatcttgggggaagcagctgtcagtgaacataccatgggggaaaccaagtcaacgttattggaaccaaaggttgctcttctagcagtgactgaacccaggatcggtatctcagaaaccaacaaggaagacgaaaatagtttgttagttaggtctgttgacaatactatgcattgtgaagagcccatttgtggtacagagacttccttcccatctcctatggaaatacaacagacagaatccttgtttccatcaacaggaatgaaacaaaccattaataatggaagggcagcagctcctgtggtaatggatgtattacaaacagatgtgtctcaaaactttggcttggaattggataccaaaagaaatgataattcagattattgtggtatttctgaaggtatggagatgaaggtggcactttcaacaacagtgagtgaaaccactgaaagcattttgcagccttcaattgaggaagctgatattttgccaataatgctttcagaagataataacccaaaatttgagccttctgttatagttacaccactggttgagagtaagtcgtgtcatctggagccttgcttacctaaagagactctagattcttcacttcagcagactgagttaatggaccacagaatggcaactggtgaaacaaactcagtatatcatgatgatgataactcggttttgagcattgaccttaatcacctgagacctattccagaagccatcagtcctctgaatagtccagtgagacctgtagcaaaagttcttagaaatgaaagcccacctcaagttccagtgtataataacagtcataaagatgtgtttttaccaaattcagctcattctacctctaagagtcagtctgatctcaataaggaaaatcaaaagccaatttacaaatctgacaaatgtacagaagcagacacatgtaagaattcaccattagatgaattagaagaaggagaaattagaagtgatagtgaaacatctaaaccacaagaaagttttgaaaaaaattccaaacgtagagtgtcagctgatgtgcggaagtcaaagactatcccacgacgtgggaaaagtactgtgtgtttagataaagacagtaggaaaacacatgtaagaatccatcagaccaataacaaatggaataaaagacctgataaatctagcagatcttcaaaaacagagaagaaagataaagtgatgagcacttccagcttggaaaaaatagttccaattattgctgtaccctcttctgaacaagagatcatgcacatgttacgaatgataagaaaacatgtaagaaaaaattatatgaaattcaaggcaaaattttcattaatacaatttcacagaattattgagtcagcaattttgagttttacatctttaattaaacatctcaacttacacaaaatctctaagtcagtgactaccttacagaagaatctctgtgatattatagagtctaaacttaagcaagttaaaaagaatggcatagttgatcgtttatttgaacagcaactaccagatatgaaaaaaaaattgtggaagtttgtagatgaccaacttgattatttgtttgcaaagcttaagaaaatcttagtatgtgattccaaaagctttggaagagatagtgatgaaggcaaacttgaaaaaacaagtaaacagaatgcacagtattcaaatagtcagaaaaggagtgtggacaactccaacagagaattgctgaaagaaaaattatcaaaatcagaagaccctgttcattataagtctttagtgggatgtaaaaaatctgaggaaaattatcaagaccaaaataactccagtattaacactgtaaagcatgacattaaaaaaaattttaacatctgctttgataatataaagaactctcaatccgaagagcgctccttggaagtacactgtccaagcaccccaaagtcagaaaaaaacgaaggaagcagcatagaggatgcacagacatcccagcatgcaactttgaagccagaacgaagtttcgagattcttaccgaacagcaagcatcgagccttacttttaatttagtgagtgatgcacaaatgggtgaaatatttaaaagtttgttgcaaggttctgatcttttagacagcagtgttaactgtactgaaaaaagtgagtgggagttaaagactccagagaagcagctgctagagactcttaagtgcgagtctataccagcttgtacaacagaagagctagtttcaggggtggcttctccatgtcctaaaatgattagtgatgataattggtcattattatcatctgaaaaaggtccatctctgtcttcagggctttcattgccggttcatcctgatgtgttggatgaaagttgtatgtttgaagtgtctactaacctacctttaagtaaagataatgtgtgtagtgtagaaaagagcaagccctgcgtttcttccatacttcttgaagatctagcagtctctttaacagtaccatcgcctctgaagtcagatggtcatctcagttttttaaagcctgatatgtcgtccagttcaactcctgaagaagtcattagtgctcattttagtgaagatgccttacttgaggaagaggatgcatctgagcaagatattcatttagctctggagtctgataattcaagcagtaaatcaagttgttcttcttcctggacaagccgatctgttgctccaggctttcagtaccaccctaatctacctatgcatgccgtcataatggaaaagtccaatgatcatttcattgtgaaaatacgacgtgcaacaccatctacctcttctggccttaaacagagtatgatgcctgatgaattattgacatctttgcccagacatggaaaggaagctgatgaaggaccagagaaagaatatatttcatgtcagaacacagtttttaaatctgtggaggaattggaaaactccaacaaaaatgttgatggcagcaagtcaactcatgaagaacagagctctatgatacaaacacaggttcctgatatatatgaatttcttaaagatgcttcagataagatgggtcatagtgatgaagtggctgatgaatgtttcaaattgcatcaagtatgggaaacaaaagtgcctgaaagcattgaagaattgccttcaatggaagaaatctcacactctgttggggaacatcttccaaacacatacgtagatctaacgaaagatccagtcactgaaaccaaaaacttgggggaattcatagaagtaacagttttacatattgatcagttgggatgttctggaggcaatttaaatcagagtgctcaaatattagacaattctttgcaggctgatactgtaggtgcttttattgatttgacacaagatgcttcaagtgaggctaaaagtgaaggtaatcatcctgcattagctgtggaagacttgggatgtggggtgatacaggtagatgaagataattgtaaggaagaaaaggcacaagtggcaaacaggcctttaaaatgcattgttgaggaaacctatatcgacttgaccacagaatctcccagttcatgtgaagtaaaaaaagatgagttaaaatcagagccaggatcaaattgtgataactcggagttgcctgggactttgcataattctcacaaaaagagaagaaacatttctgatctaaatcatcctcataaaaaacaaagaaaggaaacagacttaactaataaggaaaagaccaagaaacctacccaagattcttgtgagaatactgaagctcaccaaaagaaagccagtaagaagaaggcccctcctgtgactaaagatccctcatcattaaaggcaaccccagggattaaggattcatcagcagcacttgccacttctacaagtctttctgcaaaaaatgttattaaaaagaagggagaaattatcattttatggacaagaaatgatgaccgggaaattttattggagtgtcagaaaagagggccatcatttaaaacatttgcatatttagccgccaagttggataaaaatccaaatcaggtctcagaaagattccagcagctaatgaagctctttgaaaagtcaaaatgcagataagttgctgaattcctgggactcttaactgatattgcatactacacagaagcttcaaattcctcatgttttaaatgagcactagagggaggtttatcacctttttggttaccagatgataatctatatttgttattactcagtgactctctaatttcacatcagcatgttcagcttgtgctagtcatcattctgatttgcttatctgtttttggtcaaaatatttatttttaaacatgttagaacttaccaaaatgaaagcaacagtgatgtattgaaatcttagttttgatattttaaagaaatgactttctagattaaaaaaatagttttgtagcattttaaacttagtgactatttagttcaattgttcatccattttttatttgcttttataattgcctccttgttttggtatattgtaaaataatttaaataatgtatttataaatatgtataattatgatgtaaaataccgtgtgtatatgtatgtatgtgtgtttctgtatatgcacacacataaacggctttgcctagccaaggattttttttatctgtataaaactttttgtataaagtttgctttcaataacagtaatgtataataaaaccatgtaaagttttgttgtaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:9994 -> Molecular function: GO:0003677 [DNA binding] evidence: IEA
            GeneID:9994 -> Molecular function: GO:0003714 [transcription corepressor activity] evidence: IDA
            GeneID:9994 -> Molecular function: GO:0005123 [death receptor binding] evidence: TAS
            GeneID:9994 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:9994 -> Molecular function: GO:0008656 [cysteine-type endopeptidase activator activity involved in apoptotic process] evidence: ISS
            GeneID:9994 -> Molecular function: GO:0016505 [peptidase activator activity involved in apoptotic process] evidence: ISS
            GeneID:9994 -> Molecular function: GO:0032184 [SUMO polymer binding] evidence: IDA
            GeneID:9994 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
            GeneID:9994 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IEA
            GeneID:9994 -> Biological process: GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process] evidence: IMP
            GeneID:9994 -> Biological process: GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process] evidence: ISS
            GeneID:9994 -> Biological process: GO:0007049 [cell cycle] evidence: IEA
            GeneID:9994 -> Biological process: GO:0007165 [signal transduction] evidence: TAS
            GeneID:9994 -> Biological process: GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors] evidence: IMP
            GeneID:9994 -> Biological process: GO:0008625 [extrinsic apoptotic signaling pathway via death domain receptors] evidence: ISS
            GeneID:9994 -> Biological process: GO:0036337 [Fas signaling pathway] evidence: IMP
            GeneID:9994 -> Biological process: GO:0071260 [cellular response to mechanical stimulus] evidence: IEP
            GeneID:9994 -> Biological process: GO:0097190 [apoptotic signaling pathway] evidence: TAS
            GeneID:9994 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:9994 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:9994 -> Cellular component: GO:0005739 [mitochondrion] evidence: IDA
            GeneID:9994 -> Cellular component: GO:0016605 [PML body] evidence: IDA

by @meso_cacase at DBCLS
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