GGRNA Home | Help | Advanced search

2024-03-28 20:39:28, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001135000            2161 bp    mRNA    linear   PRI 01-JUL-2013
DEFINITION  Homo sapiens fermitin family member 2 (FERMT2), transcript variant
            3, mRNA.
ACCESSION   NM_001135000
VERSION     NM_001135000.1  GI:201861822
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2161)
  AUTHORS   Zhao,T., Guan,L., Yu,Y., Pei,X., Zhan,J., Han,L., Tang,Y., Li,F.,
            Fang,W. and Zhang,H.
  TITLE     Kindlin-2 promotes genome instability in breast cancer cells
  JOURNAL   Cancer Lett. 330 (2), 208-216 (2013)
   PUBMED   23211537
  REMARK    GeneRIF: Kindlin-2 regulates breast cancer progression by inducing
            genome instability.
REFERENCE   2  (bases 1 to 2161)
  AUTHORS   Gao,J., Khan,A.A., Shimokawa,T., Zhan,J., Stromblad,S., Fang,W. and
            Zhang,H.
  TITLE     A feedback regulation between Kindlin-2 and GLI1 in prostate cancer
            cells
  JOURNAL   FEBS Lett. 587 (6), 631-638 (2013)
   PUBMED   23337877
  REMARK    GeneRIF: A novel regulatory loop has been described between GLI1
            and Kindlin-2 that determines cancer cell viability.
REFERENCE   3  (bases 1 to 2161)
  AUTHORS   Shen,Z., Ye,Y., Kauttu,T., Seppanen,H., Vainionpaa,S., Wang,S.,
            Mustonen,H. and Puolakkainen,P.
  TITLE     The novel focal adhesion gene kindlin-2 promotes the invasion of
            gastric cancer cells mediated by tumor-associated macrophages
  JOURNAL   Oncol. Rep. 29 (2), 791-797 (2013)
   PUBMED   23151599
  REMARK    GeneRIF: the novel focal adhesion gene kindlin-2 may play an
            important role in promoting the invasion of gastric cancer cells
            mediated by tumor-associated macrophages through regulating
            interleukin expression.
REFERENCE   4  (bases 1 to 2161)
  AUTHORS   Yu,Y., Wu,J., Wang,Y., Zhao,T., Ma,B., Liu,Y., Fang,W., Zhu,W.G.
            and Zhang,H.
  TITLE     Kindlin 2 forms a transcriptional complex with beta-catenin and
            TCF4 to enhance Wnt signalling
  JOURNAL   EMBO Rep. 13 (8), 750-758 (2012)
   PUBMED   22699938
  REMARK    GeneRIF: Kindlin 2 forms a tripartite complex with beta-catenin and
            TCF4.
REFERENCE   5  (bases 1 to 2161)
  AUTHORS   Zhan,J., Zhu,X., Guo,Y., Wang,Y., Wang,Y., Qiang,G., Niu,M., Hu,J.,
            Du,J., Li,Z., Cui,J., Ma,B., Fang,W. and Zhang,H.
  TITLE     Opposite role of Kindlin-1 and Kindlin-2 in lung cancers
  JOURNAL   PLoS ONE 7 (11), E50313 (2012)
   PUBMED   23209705
  REMARK    GeneRIF: Kindlin-1 and Kindlin-2 have opposite roles in lung
            cancers
REFERENCE   6  (bases 1 to 2161)
  AUTHORS   Siegel,D.H., Ashton,G.H., Penagos,H.G., Lee,J.V., Feiler,H.S.,
            Wilhelmsen,K.C., South,A.P., Smith,F.J., Prescott,A.R.,
            Wessagowit,V., Oyama,N., Akiyama,M., Al Aboud,D., Al Aboud,K., Al
            Githami,A., Al Hawsawi,K., Al Ismaily,A., Al-Suwaid,R.,
            Atherton,D.J., Caputo,R., Fine,J.D., Frieden,I.J., Fuchs,E.,
            Haber,R.M., Harada,T., Kitajima,Y., Mallory,S.B., Ogawa,H.,
            Sahin,S., Shimizu,H., Suga,Y., Tadini,G., Tsuchiya,K., Wiebe,C.B.,
            Wojnarowska,F., Zaghloul,A.B., Hamada,T., Mallipeddi,R., Eady,R.A.,
            McLean,W.H., McGrath,J.A. and Epstein,E.H.
  TITLE     Loss of kindlin-1, a human homolog of the Caenorhabditis elegans
            actin-extracellular-matrix linker protein UNC-112, causes Kindler
            syndrome
  JOURNAL   Am. J. Hum. Genet. 73 (1), 174-187 (2003)
   PUBMED   12789646
REFERENCE   7  (bases 1 to 2161)
  AUTHORS   Weinstein,E.J., Bourner,M., Head,R., Zakeri,H., Bauer,C. and
            Mazzarella,R.
  TITLE     URP1: a member of a novel family of PH and FERM domain-containing
            membrane-associated proteins is significantly over-expressed in
            lung and colon carcinomas
  JOURNAL   Biochim. Biophys. Acta 1637 (3), 207-216 (2003)
   PUBMED   12697302
REFERENCE   8  (bases 1 to 2161)
  AUTHORS   Tu,Y., Wu,S., Shi,X., Chen,K. and Wu,C.
  TITLE     Migfilin and Mig-2 link focal adhesions to filamin and the actin
            cytoskeleton and function in cell shape modulation
  JOURNAL   Cell 113 (1), 37-47 (2003)
   PUBMED   12679033
REFERENCE   9  (bases 1 to 2161)
  AUTHORS   Heilig,R., Eckenberg,R., Petit,J.L., Fonknechten,N., Da Silva,C.,
            Cattolico,L., Levy,M., Barbe,V., de Berardinis,V., Ureta-Vidal,A.,
            Pelletier,E., Vico,V., Anthouard,V., Rowen,L., Madan,A., Qin,S.,
            Sun,H., Du,H., Pepin,K., Artiguenave,F., Robert,C., Cruaud,C.,
            Bruls,T., Jaillon,O., Friedlander,L., Samson,G., Brottier,P.,
            Cure,S., Segurens,B., Aniere,F., Samain,S., Crespeau,H., Abbasi,N.,
            Aiach,N., Boscus,D., Dickhoff,R., Dors,M., Dubois,I., Friedman,C.,
            Gouyvenoux,M., James,R., Madan,A., Mairey-Estrada,B., Mangenot,S.,
            Martins,N., Menard,M., Oztas,S., Ratcliffe,A., Shaffer,T.,
            Trask,B., Vacherie,B., Bellemere,C., Belser,C., Besnard-Gonnet,M.,
            Bartol-Mavel,D., Boutard,M., Briez-Silla,S., Combette,S.,
            Dufosse-Laurent,V., Ferron,C., Lechaplais,C., Louesse,C.,
            Muselet,D., Magdelenat,G., Pateau,E., Petit,E.,
            Sirvain-Trukniewicz,P., Trybou,A., Vega-Czarny,N., Bataille,E.,
            Bluet,E., Bordelais,I., Dubois,M., Dumont,C., Guerin,T.,
            Haffray,S., Hammadi,R., Muanga,J., Pellouin,V., Robert,D.,
            Wunderle,E., Gauguet,G., Roy,A., Sainte-Marthe,L., Verdier,J.,
            Verdier-Discala,C., Hillier,L., Fulton,L., McPherson,J.,
            Matsuda,F., Wilson,R., Scarpelli,C., Gyapay,G., Wincker,P.,
            Saurin,W., Quetier,F., Waterston,R., Hood,L. and Weissenbach,J.
  TITLE     The DNA sequence and analysis of human chromosome 14
  JOURNAL   Nature 421 (6923), 601-607 (2003)
   PUBMED   12508121
REFERENCE   10 (bases 1 to 2161)
  AUTHORS   Wick,M., Burger,C., Brusselbach,S., Lucibello,F.C. and Muller,R.
  TITLE     Identification of serum-inducible genes: different patterns of gene
            regulation during G0-->S and G1-->S progression
  JOURNAL   J. Cell. Sci. 107 (PT 1), 227-239 (1994)
   PUBMED   8175911
  REMARK    Erratum:[J Cell Sci. 1994 Mar;107 ( Pt 3):preceding table of
            contents. PMID: 8006057]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC017327.2 and BX161467.1.
            
            Transcript Variant: This variant (3) contains an additional
            in-frame coding exon and is missing the 3' terminal exon compared
            to variant 1. This results in a shorter isoform (3) with a distinct
            C-terminus and an internal 7 aa segment missing in isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX161467.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           ERS025081, ERS025082 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                BC017327.2         1-79
            80-2161             BX161467.1         1-2082
FEATURES             Location/Qualifiers
     source          1..2161
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q22.1"
     gene            1..2161
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /note="fermitin family member 2"
                     /db_xref="GeneID:10979"
                     /db_xref="HGNC:15767"
                     /db_xref="MIM:607746"
     exon            1..177
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /inference="alignment:Splign:1.39.8"
     variation       157
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2297300"
     misc_feature    166..168
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /note="upstream in-frame stop codon"
     exon            178..343
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /inference="alignment:Splign:1.39.8"
     CDS             187..2088
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /note="isoform 3 is encoded by transcript variant 3;
                     pleckstrin homology domain containing, family C (with FERM
                     domain) member 1; kindlin-2; mitogen inducible gene 2
                     protein; pleckstrin homology domain containing, family C
                     member 1; kindlin 2; mitogen-inducible gene 2 protein; PH
                     domain-containing family C member 1; pleckstrin homology
                     domain-containing family C member 1; fermitin family
                     homolog 2"
                     /codon_start=1
                     /product="fermitin family homolog 2 isoform 3"
                     /protein_id="NP_001128472.1"
                     /db_xref="GI:201861823"
                     /db_xref="CCDS:CCDS45108.1"
                     /db_xref="GeneID:10979"
                     /db_xref="HGNC:15767"
                     /db_xref="MIM:607746"
                     /translation="
MALDGIRMPDGCYADGTWELSVHVTDLNRDVTLRVTGEVHIGGVMLKLVEKLDVKKDWSDHALWWEKKRTWLLKTHWTLDKYGIQADAKLQFTPQHKLLRLQLPNMKYVKVKVNFSDRVFKAVSDICKTFNIRHPEELSLLKKPRDPTKKKKKKLDDQSEDEALELEGPLITPGSGSIYSSPGLYSKTMTPTYDAHDGSPLSPTSAWFGDSALSEGNPGILAVSQPITSPEILAKMFKPQALLDKAKINQGWLDSSRSLMEQDVKENEALLLRFKYYSFFDLNPKYDAIRINQLYEQAKWAILLEEIECTEEEMMMFAALQYHINKLSIMTSENHLNNSDKEVDEVDAALSDLEITLEGGKTSTILGDITSIPELADYIKVFKPKKLTLKGYKQYWCTFKDTSISCYKSKEESSGTPAHQMNLRGCEVTPDVNISGQKFNIKLLIPVAEGMNEIWLRCDNEKQYAHWMAACRLASKGKTMADSSYNLEVQNILSFLKMQHLNPDPQLIPEQITTDITPECLVSPRYLKKYKNKQPGYIRDLITARILEAHQNVAQMSLIEAKMRFIQAWQSLPEFGITHFIARFQGGKKEELIGIAYNRLIRMDASTGDAIKTWRFSNMKQWNVNWEIKMVNS
"
     misc_feature    304..429
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="propagated from UniProtKB/Swiss-Prot (Q96AC1.1);
                     Region: Interaction with membranes containing
                     phosphatidylinositol phosphate"
     misc_feature    661..663
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q96AC1.1); phosphorylation site"
     misc_feature    727..729
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q96AC1.1); phosphorylation site"
     misc_feature    <907..>1158
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /note="Band 4.1 homologues; Region: B41; smart00295"
                     /db_xref="CDD:197635"
     misc_feature    1039..>1164
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /note="FERM central domain; Region: FERM_M; pfam00373"
                     /db_xref="CDD:201187"
     misc_feature    1201..1203
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q96AC1.1); phosphorylation site"
     misc_feature    1237..1239
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /note="Phosphoserine; propagated from UniProtKB/Swiss-Prot
                     (Q96AC1.1); phosphorylation site"
     misc_feature    1303..1620
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /note="Unc-112 pleckstrin homology (PH) domain; Region:
                     Unc112; cd01237"
                     /db_xref="CDD:176313"
     misc_feature    order(1309..1332,1363..1386,1390..1410,1441..1479,
                     1504..1524,1543..1560,1573..1608)
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /note="core domain; other site"
                     /db_xref="CDD:176313"
     misc_feature    <1759..1926
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /note="FERM central domain; Region: FERM_M; pfam00373"
                     /db_xref="CDD:201187"
     exon            344..577
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /inference="alignment:Splign:1.39.8"
     exon            578..712
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /inference="alignment:Splign:1.39.8"
     STS             649..1009
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /standard_name="Plekhc1"
                     /db_xref="UniSTS:498247"
     exon            713..938
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /inference="alignment:Splign:1.39.8"
     exon            939..1041
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /inference="alignment:Splign:1.39.8"
     exon            1042..1149
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /inference="alignment:Splign:1.39.8"
     exon            1150..1284
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /inference="alignment:Splign:1.39.8"
     variation       1263
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1130597"
     exon            1285..1334
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /inference="alignment:Splign:1.39.8"
     exon            1335..1459
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /inference="alignment:Splign:1.39.8"
     exon            1460..1566
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /inference="alignment:Splign:1.39.8"
     exon            1567..1788
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /inference="alignment:Splign:1.39.8"
     exon            1789..1809
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /inference="alignment:Splign:1.39.8"
     exon            1810..1934
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /inference="alignment:Splign:1.39.8"
     exon            1935..2161
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
                     /inference="alignment:Splign:1.39.8"
     polyA_signal    2138..2143
                     /gene="FERMT2"
                     /gene_synonym="KIND2; mig-2; MIG2; PLEKHC1; UNC112;
                     UNC112B"
ORIGIN      
gggtggagcgcggggagccaggcgaggggccgcgacgacgggactccattagccgctccggccacaggcagcgcttcgccagccgaggaaccggacgcggacaccgccgccccgcgagcctccagcccctcgcctgttgccgcgcgagtcccgggcccggagcgctaggagcgcgcggaaggagccatggctctggacgggataaggatgccagatggctgctacgcggacgggacgtgggaactgagtgtccatgtgacggacctgaaccgcgatgtcaccctgagagtgaccggcgaggtgcacattggaggcgtgatgcttaagctggtggagaaactcgatgtaaaaaaagattggtctgaccatgctctctggtgggaaaagaagagaacttggcttctgaagacacattggaccttagataagtatggtattcaggcagatgctaagcttcagttcacccctcagcacaaactgctccgcctgcagcttcccaacatgaagtatgtgaaggtgaaagtgaatttctctgatagagtcttcaaagctgtttctgacatctgtaagacttttaatatcagacaccccgaagaactttctctcttaaagaaacccagagatccaacaaagaaaaaaaagaagaagctagatgaccagtctgaagatgaggcacttgaattagaggggcctcttatcactcctggatcaggaagtatatattcaagcccaggactgtatagtaaaacaatgacccccacttatgatgctcatgatggaagccccttgtcaccaacttctgcttggtttggtgacagtgctttgtcagaaggcaatcctggtatacttgctgtcagtcaaccaatcacgtcaccagaaatcttggcaaaaatgttcaagcctcaagctcttcttgataaagcaaaaatcaaccaaggatggcttgattcctcaagatctctcatggaacaagatgtgaaggaaaatgaggccttgctgctccgattcaagtattacagcttttttgatttgaatccaaagtatgatgcaatcagaatcaatcagctttacgagcaggccaaatgggccattctcctggaagagattgaatgcacagaagaagaaatgatgatgtttgcagccctgcagtatcatatcaataagctgtcaatcatgacatcagagaatcatttgaacaacagtgacaaagaagttgatgaagttgatgctgccctttcagacctggagattactctggaagggggtaaaacgtcaacaattttgggtgacattacttccattcctgaacttgctgactacattaaagttttcaagccaaaaaagctgactctgaaaggttacaaacaatattggtgcaccttcaaagacacatccatttcttgttataagagcaaagaagaatccagtggcacaccagctcatcagatgaacctcaggggatgtgaagttaccccagatgtaaacatttcaggccaaaaatttaacattaaactcctgattccagttgcagaaggcatgaatgaaatctggcttcgttgtgacaatgaaaaacagtatgcacactggatggcagcctgcagattagcctccaaaggcaagaccatggcggacagttcttacaacttagaagttcagaatattctttcctttctgaagatgcagcatttaaacccagatcctcagttaataccagagcagatcacgactgatataactcctgaatgtttggtgtctccccgctatctaaaaaagtataagaacaagcagccaggctatataagagatttgataacagcgagaatcttggaggcccatcagaatgtagctcagatgagtctaattgaagccaagatgagatttattcaagcttggcagtcactacctgaatttggcatcactcacttcattgcaaggttccaagggggcaaaaaagaagaacttattggaattgcatacaacagactgattcggatggatgccagcactggagatgcaattaaaacatggcgtttcagcaacatgaaacagtggaatgtcaactgggaaatcaaaatggtaaactcataacaatgttacttgaatatagtccttctctgatacaaattagtacattaagaataaaaaggcctataaattctga
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:10979 -> Molecular function: GO:0005547 [phosphatidylinositol-3,4,5-trisphosphate binding] evidence: IDA
            GeneID:10979 -> Biological process: GO:0007160 [cell-matrix adhesion] evidence: IMP
            GeneID:10979 -> Biological process: GO:0007160 [cell-matrix adhesion] evidence: ISS
            GeneID:10979 -> Biological process: GO:0007179 [transforming growth factor beta receptor signaling pathway] evidence: IMP
            GeneID:10979 -> Biological process: GO:0007229 [integrin-mediated signaling pathway] evidence: IMP
            GeneID:10979 -> Biological process: GO:0008360 [regulation of cell shape] evidence: IEA
            GeneID:10979 -> Biological process: GO:0016055 [Wnt receptor signaling pathway] evidence: IMP
            GeneID:10979 -> Biological process: GO:0030036 [actin cytoskeleton organization] evidence: NAS
            GeneID:10979 -> Biological process: GO:0033622 [integrin activation] evidence: IMP
            GeneID:10979 -> Biological process: GO:0034329 [cell junction assembly] evidence: TAS
            GeneID:10979 -> Biological process: GO:0034446 [substrate adhesion-dependent cell spreading] evidence: ISS
            GeneID:10979 -> Biological process: GO:0048041 [focal adhesion assembly] evidence: ISS
            GeneID:10979 -> Biological process: GO:0072657 [protein localization to membrane] evidence: ISS
            GeneID:10979 -> Cellular component: GO:0001725 [stress fiber] evidence: IEA
            GeneID:10979 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:10979 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
            GeneID:10979 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
            GeneID:10979 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:10979 -> Cellular component: GO:0005925 [focal adhesion] evidence: IDA
            GeneID:10979 -> Cellular component: GO:0005938 [cell cortex] evidence: IEA
            GeneID:10979 -> Cellular component: GO:0009986 [cell surface] evidence: IEA
            GeneID:10979 -> Cellular component: GO:0031234 [extrinsic to internal side of plasma membrane] evidence: IDA
            GeneID:10979 -> Cellular component: GO:0031258 [lamellipodium membrane] evidence: IEA
            GeneID:10979 -> Cellular component: GO:0031674 [I band] evidence: IEA
            GeneID:10979 -> Cellular component: GO:0031941 [filamentous actin] evidence: IEA

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.