Home |
Help |
Advanced search
2024-04-23 18:51:12, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001130927 5301 bp mRNA linear PRI 17-APR-2013
DEFINITION Homo sapiens myocyte enhancer factor 2A (MEF2A), transcript variant
3, mRNA.
ACCESSION NM_001130927
VERSION NM_001130927.1 GI:195972802
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5301)
AUTHORS Nitert,M.D., Dayeh,T., Volkov,P., Elgzyri,T., Hall,E., Nilsson,E.,
Yang,B.T., Lang,S., Parikh,H., Wessman,Y., Weishaupt,H., Attema,J.,
Abels,M., Wierup,N., Almgren,P., Jansson,P.A., Ronn,T., Hansson,O.,
Eriksson,K.F., Groop,L. and Ling,C.
TITLE Impact of an exercise intervention on DNA methylation in skeletal
muscle from first-degree relatives of patients with type 2 diabetes
JOURNAL Diabetes 61 (12), 3322-3332 (2012)
PUBMED 23028138
REMARK GeneRIF: DNA methylation of genes in retinol metabolism and calcium
signaling pathways (P < 3 x 10-6) and with known functions in
muscle and T2D including MEF2A, RUNX1, NDUFC2, and THADA decreased
after exercise
REFERENCE 2 (bases 1 to 5301)
AUTHORS Zhao,W., Zhao,S.P. and Peng,D.Q.
TITLE The effects of myocyte enhancer factor 2A gene on the
proliferation, migration and phenotype of vascular smooth muscle
cells
JOURNAL Cell Biochem. Funct. 30 (2), 108-113 (2012)
PUBMED 22028303
REMARK GeneRIF: MEF2A dominant negative mutation enhanced cell
proliferation and cell migration.
REFERENCE 3 (bases 1 to 5301)
AUTHORS Liu,Y., Niu,W., Wu,Z., Su,X., Chen,Q., Lu,L. and Jin,W.
TITLE Variants in exon 11 of MEF2A gene and coronary artery disease:
evidence from a case-control study, systematic review, and
meta-analysis
JOURNAL PLoS ONE 7 (2), E31406 (2012)
PUBMED 22363637
REMARK GeneRIF: The rare 21-bp deletion might have a more compelling
effect on coronary artery disease (CAD) than the common (CAG)(n)
polymorphism, and MEF2A genetic variant might be a rare but
specific cause of CAD/myocardial infarction.
Review article
REFERENCE 4 (bases 1 to 5301)
AUTHORS Katsarou,K., Tsitoura,P. and Georgopoulou,U.
TITLE MEK5/ERK5/mef2: a novel signaling pathway affected by hepatitis C
virus non-enveloped capsid-like particles
JOURNAL Biochim. Biophys. Acta 1813 (10), 1854-1862 (2011)
PUBMED 21767578
REMARK GeneRIF: HCVne particles are capable of inducing the recently
discovered ERK5 pathway, in a dose dependent way.
REFERENCE 5 (bases 1 to 5301)
AUTHORS She,H. and Mao,Z.
TITLE Regulation of myocyte enhancer factor-2 transcription factors by
neurotoxins
JOURNAL Neurotoxicology 32 (5), 563-566 (2011)
PUBMED 21741404
REMARK GeneRIF: [review] In this work, the mechanisms of regulation of
MEF2 function by several well-known neurotoxins and their
implications in various neurodegenerative diseases are reviewed.
Review article
REFERENCE 6 (bases 1 to 5301)
AUTHORS Molkentin,J.D., Black,B.L., Martin,J.F. and Olson,E.N.
TITLE Cooperative activation of muscle gene expression by MEF2 and
myogenic bHLH proteins
JOURNAL Cell 83 (7), 1125-1136 (1995)
PUBMED 8548800
REFERENCE 7 (bases 1 to 5301)
AUTHORS Hobson,G.M., Krahe,R., Garcia,E., Siciliano,M.J. and Funanage,V.L.
TITLE Regional chromosomal assignments for four members of the MADS
domain transcription enhancer factor 2 (MEF2) gene family to human
chromosomes 15q26, 19p12, 5q14, and 1q12-q23
JOURNAL Genomics 29 (3), 704-711 (1995)
PUBMED 8575763
REFERENCE 8 (bases 1 to 5301)
AUTHORS Funk,W.D. and Wright,W.E.
TITLE Cyclic amplification and selection of targets for multicomponent
complexes: myogenin interacts with factors recognizing binding
sites for basic helix-loop-helix, nuclear factor 1,
myocyte-specific enhancer-binding factor 2, and COMP1 factor
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 89 (20), 9484-9488 (1992)
PUBMED 1329097
REFERENCE 9 (bases 1 to 5301)
AUTHORS Yu,Y.T., Breitbart,R.E., Smoot,L.B., Lee,Y., Mahdavi,V. and
Nadal-Ginard,B.
TITLE Human myocyte-specific enhancer factor 2 comprises a group of
tissue-restricted MADS box transcription factors
JOURNAL Genes Dev. 6 (9), 1783-1798 (1992)
PUBMED 1516833
REFERENCE 10 (bases 1 to 5301)
AUTHORS Pollock,R. and Treisman,R.
TITLE Human SRF-related proteins: DNA-binding properties and potential
regulatory targets
JOURNAL Genes Dev. 5 (12A), 2327-2341 (1991)
PUBMED 1748287
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA778137.1, AK294207.1,
BC013437.2, AB208985.1, AC022692.11 and N93079.1.
Summary: The protein encoded by this gene is a DNA-binding
transcription factor that activates many muscle-specific, growth
factor-induced, and stress-induced genes. The encoded protein can
act as a homodimer or as a heterodimer and is involved in several
cellular processes, including muscle development, neuronal
differentiation, cell growth control, and apoptosis. Defects in
this gene could be a cause of autosomal dominant coronary artery
disease 1 with myocardial infarction (ADCAD1). Several transcript
variants encoding different isoforms have been found for this
gene.[provided by RefSeq, Jan 2010].
Transcript Variant: This variant (3) uses two alternate coding
exons, and lacks a 5' non-coding exon as well as another in-frame
coding exon, compared to transcript variant 1. This results in a
shorter isoform (3) missing an internal protein segment, and with
two varied internal segments, compared to isoform 1.
Sequence Note: This RefSeq record was created from transcript and
genomic sequence data because no single transcript was available
for the full length of the gene. The extent of this transcript is
supported by transcript alignments.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AK294207.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025082, ERS025083 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-62 DA778137.1 1-62
63-999 AK294207.1 1-937
1000-1784 BC013437.2 1186-1970
1785-2622 AB208985.1 2232-3069
2623-5088 AC022692.11 153286-155751
5089-5301 N93079.1 1-213 c
FEATURES Location/Qualifiers
source 1..5301
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/map="15q26"
gene 1..5301
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/note="myocyte enhancer factor 2A"
/db_xref="GeneID:4205"
/db_xref="HGNC:6993"
/db_xref="MIM:600660"
exon 1..177
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
exon 178..373
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
misc_feature 311..313
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/note="upstream in-frame stop codon"
CDS 320..1633
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/note="isoform 3 is encoded by transcript variant 3; MADS
box transcription enhancer factor 2, polypeptide A
(myocyte enhancer factor 2A); myocyte-specific enhancer
factor 2A; serum response factor-like protein 1"
/codon_start=1
/product="myocyte-specific enhancer factor 2A isoform 3"
/protein_id="NP_001124399.1"
/db_xref="GI:195972803"
/db_xref="CCDS:CCDS45363.1"
/db_xref="GeneID:4205"
/db_xref="HGNC:6993"
/db_xref="MIM:600660"
/translation="
MGRKKIQITRIMDERNRQTLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNEDSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLSEEEELELNTQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTEDRESPSVKRMRMDAWVT
"
misc_feature 323..>394
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/note="MADS: MCM1, Agamous, Deficiens, and SRF (serum
response factor) box family of eukaryotic transcriptonal
regulators. Binds DNA and exists as hetero and
homo-dimers. Composed of 2 main subgroups: SRF-like/Type
I and MEF2-like (myocyte enhancer factor 2)/...; Region:
MADS; cl00109"
/db_xref="CDD:198517"
misc_feature 398..574
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/note="Holliday junction regulator protein family
C-terminal repeat; Region: HJURP_C; pfam12347"
/db_xref="CDD:152782"
STS 329..536
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/standard_name="Mef2a"
/db_xref="UniSTS:265600"
STS 329..485
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/standard_name="Mef2a"
/db_xref="UniSTS:265601"
variation 343
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:370523988"
exon 374..505
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 374
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:17423081"
variation 381
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:3205682"
variation 396
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:368757733"
variation 397
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:1135555"
variation 403
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:1135556"
variation 406
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:1135557"
variation 412
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:1135558"
variation 415
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:1135559"
variation 416
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:1135560"
variation 421
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:1135561"
variation 428
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:1135562"
variation 432
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:3208173"
variation 438
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:1135563"
variation 445
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:1136937"
variation 448
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:3198317"
variation 451
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:1135564"
variation 454
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:1135565"
variation 460
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:1135566"
variation 462
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:1135567"
variation 463
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:1135568"
variation 467
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:1135569"
variation 475
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:1135570"
variation 480
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:1135571"
variation 485
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:1135572"
variation 486
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:1135574"
variation 501
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:1135575"
variation 505
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:17420057"
exon 506..725
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 576
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:374058145"
variation 626
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:189538320"
variation 628
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:3803420"
variation 661
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:146192119"
variation 672
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:370083199"
variation 707
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:373867888"
exon 726..785
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 738
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:199820037"
variation 754
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:376779827"
variation 767
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:377207410"
exon 786..973
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 852
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:189526729"
variation 866
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:199751824"
variation 871
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:369943942"
variation 897
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:121918530"
variation 905
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:79454361"
variation 916
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:200748600"
variation 943
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:369552532"
variation 944
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:373219260"
variation 945
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:121918529"
variation 957
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:121918531"
variation 970
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:376183174"
exon 974..997
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 976
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:367777547"
variation 977
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:371903721"
variation 989
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:148427051"
variation 990
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:370231805"
exon 998..1124
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 1000..1001
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:17854846"
variation 1000
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:325408"
variation 1006
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:325407"
variation 1045
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:3730283"
variation 1081
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:372479689"
variation 1103
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:373204094"
exon 1125..1251
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 1138
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:373943430"
variation 1141
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:368107439"
variation 1142
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:373128826"
exon 1252..5287
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/inference="alignment:Splign:1.39.8"
variation 1252
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:199613639"
variation 1281
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:375108417"
variation 1294
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:369483642"
STS 1311..1468
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/standard_name="G64293"
/db_xref="UniSTS:158672"
variation 1347
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:372533601"
variation 1357
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:144461661"
variation 1359
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:369579124"
variation 1360
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:3730059"
variation 1366..1367
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="cagcag"
/db_xref="dbSNP:374033278"
variation 1367..1372
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="cagcag"
/db_xref="dbSNP:3138597"
variation 1367..1369
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="cag"
/db_xref="dbSNP:373652230"
variation 1371..1376
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="agcagc"
/db_xref="dbSNP:58424802"
variation 1375..1380
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="gcagca"
/db_xref="dbSNP:72276751"
variation 1376..1377
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="cagcag"
/db_xref="dbSNP:72236998"
variation 1377..1378
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="agcagc"
/db_xref="dbSNP:72416294"
variation 1383
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:200861006"
variation 1386..1391
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="agcagc"
/db_xref="dbSNP:72198683"
variation 1395
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:201861701"
variation 1398
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:199811207"
variation 1404
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:369815961"
variation 1414
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:367780642"
variation 1462
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:325400"
variation 1478
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:370921147"
variation 1549
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:34851361"
variation 1550
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:111748677"
variation 1563
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:370778860"
variation 1778..1779
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="gtgt"
/db_xref="dbSNP:145618675"
variation 1778
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:201277440"
variation 1779..1780
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="gtgt"
/db_xref="dbSNP:144020290"
variation 1780..1781
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="gtgt"
/db_xref="dbSNP:10628004"
variation 1785..1786
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="gtgt"
/db_xref="dbSNP:34507751"
variation 1785
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:28444186"
variation 1825
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:374107493"
variation 1872
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:376220587"
variation 2136
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:75665175"
variation 2147
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:140014502"
variation 2159
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:72760574"
variation 2201
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:190007997"
variation 2208
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:201784078"
variation 2208
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="g"
/db_xref="dbSNP:34756453"
variation 2273
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:145205421"
variation 2285
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:11635271"
STS 2288..2637
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/standard_name="D15S907"
/db_xref="UniSTS:279"
variation 2498
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:182261693"
variation 2649
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:1059750"
variation 2650
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:186608671"
variation 2675
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:1454315"
variation 2825
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:190999757"
variation 3055..3059
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="gttaa"
/db_xref="dbSNP:71982844"
variation 3062
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="aactt"
/db_xref="dbSNP:67611863"
variation 3065
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:1059755"
variation 3066
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:149125295"
variation 3070
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:1059756"
variation 3076
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:1059757"
variation 3100..3101
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:1059758"
variation 3101
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:325399"
variation 3106
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:1136940"
variation 3291
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:142460833"
variation 3292
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:184041593"
variation 3317
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:368872347"
variation 3382
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:897074"
variation 3610
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:188542083"
variation 3629
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:372386338"
variation 3661
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:375267826"
variation 3668
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:59420387"
variation 3670
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:12902459"
variation 3671..3672
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="a"
/db_xref="dbSNP:67644135"
variation 3672
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="c"
/db_xref="dbSNP:58267790"
variation 3674..3675
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="cc"
/db_xref="dbSNP:141367967"
variation 3674
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="c"
/db_xref="dbSNP:144314500"
variation 3676
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:11550216"
variation 3677
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:75869168"
variation 3678
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:148429386"
variation 3683
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="c"
/replace="cc"
/db_xref="dbSNP:58849948"
variation 3691
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:1059759"
variation 3703
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:325383"
variation 3761
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="g"
/db_xref="dbSNP:325382"
variation 3829
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:1059760"
variation 3842
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:11550217"
variation 3847
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:193162969"
variation 3866
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:184981047"
variation 3869
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:187250165"
variation 3952
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:372383636"
variation 4009
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:146891523"
variation 4199
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:191660882"
variation 4308
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:41303617"
variation 4389
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:140716704"
variation 4471
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:325381"
variation 4472
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="g"
/db_xref="dbSNP:200152842"
variation 4490
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:183911417"
variation 4568
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:113970475"
variation 4596
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:188188955"
variation 4601
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="a"
/db_xref="dbSNP:34602555"
variation 4680
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:182321371"
variation 4682
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:113827147"
variation 4722
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:145829205"
variation 4729..4730
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="cat"
/db_xref="dbSNP:374735275"
variation 4729
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:77710130"
variation 4730..4731
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace=""
/replace="atc"
/db_xref="dbSNP:371572866"
variation 4749
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:28377673"
variation 4763
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="t"
/db_xref="dbSNP:138403437"
variation 4874
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="g"
/db_xref="dbSNP:74033759"
STS 5012..5284
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/standard_name="D15S901"
/db_xref="UniSTS:13157"
variation 5135
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="c"
/replace="t"
/db_xref="dbSNP:150316263"
variation 5197
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="a"
/replace="c"
/db_xref="dbSNP:12442844"
polyA_site 5215
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
polyA_signal 5239..5244
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
polyA_site 5268
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
variation 5275
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
/replace="g"
/replace="t"
/db_xref="dbSNP:325380"
polyA_site 5287
/gene="MEF2A"
/gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
ORIGIN
agaacgagttccggtctggccgaggcttgtctcctaaaaatagccccggtgtggggatccgtgcgcggatgtcccggcgagtcccgggctgaaagaggcggctccgggcggcgcgaagcgctggtggcgggcccgggctgcggcgtgtgcgcgcccgccagctgctccggagatacgatcttgtagaaaatttcagctgtagcccttggactagaagctgaaataacagaagctgtgtacgatgcattagggtattgaagaaaattaacttttgaattaaatatttggaatataaggaaataaggaaagttgactgaaaatggggcggaagaaaatacaaatcacacgcataatggatgaaaggaaccgacagactttaagaaagaaaggccttaatggttgtgagagccctgatgctgacgattactttgagcacagtccactctcggaggacagattcagcaaactaaatgaagatagtgattttattttcaaacgaggccctcctggtctgccacctcagaacttttcaatgtctgtcacagttccagtgaccagccccaatgctttgtcctacactaacccagggagttcactggtgtccccatctttggcagccagctcaacgttaacagattcaagcatgctctctccacctcaaaccacattacatagaaatgtgtctcctggagctcctcagagaccaccaagtactggcaatgcaggtgggatgttgagcactacagacctcacagtgccaaatggagctggaagcagtccagtggggaatggatttgtaaactcaagagcttctccaaatttgattggagctactggtgcaaatagcttaggcaaagtcatgcctacaaagtctccccctccaccaggtggtggtaatcttggaatgaacagtaggaaaccagatcttcgagttgtcatccccccttcaagcaagggcatgatgcctccactatcggaggaagaggaattggagttgaatacccaaaggatcagtagttctcaagccactcaacctcttgctaccccagtcgtgtctgtgacaaccccaagcttgcctccgcaaggacttgtgtactcagcaatgccgactgcctacaacactgattattcactgaccagcgctgacctgtcagcccttcaaggcttcaactcgccaggaatgctgtcgctgggacaggtgtcggcctggcagcagcaccacctaggacaagcagccctcagctctcttgttgctggagggcagttatctcagggttccaatttatccattaataccaaccaaaacatcagcatcaagtccgaaccgatttcacctcctcgggatcgtatgaccccatcgggcttccagcagcagcagcagcagcagcagcagcagcagccgccgccaccaccgcagccccagccacaacccccgcagccccagccccgacaggaaatggggcgctcccctgtggacagtctgagcagctctagtagctcctatgatggcagtgatcgggaggatccacggggcgacttccattctccaattgtgcttggccgacccccaaacactgaggacagagaaagcccttctgtaaagcgaatgaggatggacgcgtgggtgacctaaggcttccaagctgatgtttgtacttttgtgttactgcagtgacctgccctacatatctaaatcggtaaataaggacatgagttaaatatatttatatgtacatacatatatatatccctttacatatatatgtatgtgggtgtgagtgtgtatgtgtgggtgtgtgttacatacacagaatcaggcacttacctgcaaactccttgtaggtctgcagatgtgtgtcccatggcagacaaagcaccctgtaggcacagacaagtctggcacttccttggactacttgtttcgtaaagataaccagtttttgcagagaaacgtgtacccatatataattctcccacactagcttgcagaaacctagagggccccctacttgttttatttaactgtgcagtgactgtagttacttaagagaaaatgctttgtagaacagagcagtagaaaagcaggaaccaagaaagcaatactgtacataaaatgtcatttatattttccaacctggcatgggtgtctgttgcaaaggggtgcatgggaaagggctgttgatattaaaaacaaacaaaacaaaaaagccccacacataactgttttgcacgtgcaaaaatgtattgggtcaagaagtgatctttagctaataaagaaagagaatagaaaacacgcatgagatattcagaaaatactagcctagaaatatagagcattaacaaagtaaaattaatatattaagttataattggaatatgtcagaagtttctttttacattcatatcttaaaaattaaagaaactgattttagctcatgtatattttatatgaaagaaaacacccttatgaattgatgactatatataaaattatattcactacttttgaacacattctgctatgaattatttatataagccaaagctatatgttgtaacttttttttagagaatagctttatcttggtttaactctttagttttattttaagaggggaaaacaaaaatatcttgcaagcagaaccttggaaaaaaaaagccatgaacacttattctaaatgtaaattaaaagttgagccaaactctttgtgtatatagcatcttaaatatattatcacctttgatgtaagtacctatgtattgtatggtcaccagattaaaaagtatatttttgtggattgccgccaatctggggggaaaaggcgaggtcctttattaagtattcactgtttaatatttactattttgttaaatatactgtactttggattttaattattagcccagttttttcagaggattgtataaaggggtttctcccctcactggtggtgaatgtgtgatgttacattgtaatctttgtgctgtatgggttgagcatcattatatattttgtatgtgtacataaatagcaaagtggcaaaaaaaattggtgttaagttcatcctgcataagtataaaatgtgttgtaacagattttgtaaggcattatttaaaacttgccttttgtgaggaaaaaatgtagtagaaaaagctgacctaatttaattaatattagagaaaatggcaaaatagtagatgagcacaaaggttttataagtggtaaatgattaggggaaaataatcatggggaaagggatcttttttccttgaccctctgaaaacagaacgatgcagctggttacaaaatcctaccgttatcagctcttctgcacattgcagtgatgctttggtatgcggggagaaacactcttagggtgctggtccttggcatgactcttgccattctaattggaattagtgccaccctcagcttggattttgaacaaggccttattctttcaggaagacaactaatggatgatagcaagttcatccacttactgggcttgtgccatgagcaaaattcaaagtcctgtatatctttcattgtagatttttaaatactccttttcctaaaaaactcaagggtttaaaaattgctattttatattttaaatgatattgagcagctacctacaatttctatgtacattttgttcccccccccccaccccccccccaaattacgttccttttgacattttcctcatctgctgtttgtgacaagtcatcagccagatttcctgactgacacataggtatgatcagtgcaggagagacctgcgcaccacaggctgcaaactggaggttctgttctcatggcagtttgggcagtaacttttgagagaggccaaaaaaaggaggatgacatgctgtctcctctcttcagtatagacattaggctcttattcagaaaggatttttctttaaaaatgtacttactttactgaactacttacaggcacatttcttcataaggccacacctaatccaaacaagacagtctcccaacactgaagttccaaaataatccttaccactttgtaaaccatttatagctttgaaagtgttaagtgattccttcgttattatttatgcatgttcatgaacttctgctgtacattggaataggagttaacacattcacatttactgtctattttcttgtgtgccttatgagatggcttttctgactgtatctcaatagtctttctttctatgcaggtttataatcagtacaactactgttttctaaaatactactactcaaggctcggagtttgtatttaaattacactgaccaagtaacaatgtattccatttcaggaactgaatatttgactgttaacctttttcccatacgtccagtgtggcatggagcatatggacttgacagacatctctcacccagacgcccacgtgtgaacacacccacatccacatctctgggtggaaaccagcctagagaggggacgacgctaatggtgttgctttagaaccgtcttttcttacccttttagactcgtgttttgtatgagacaccattgcaagaaaattttatccctccagaagtattttattactaaagaacaaaagcaaaaaaagcttaaattgcactggttaaagtacagtttccaacagctgtccttcctcagtactctaatggccactccaccgcgagtggaagtcactgttgtgtgtacacaggtggtcccaatcaaaactccatcttttgagcccaattatgtccattttgttatagactaaatcaggggtttgttctacaagaacaatacatgttttaccctttcctttaactagaaggataactagtaatgcatcaacataatttctgtattaaccatcatgcgcacaagaaatacatagtaaataaggaagctgaaaactcctggcattggatcttaagctagatgattagaatgtgaaaaagattttacaaatgtaaaacttctatttctctgtagaaactttcttcactttgctgtgcaagaagacactgctttgctatatttaaaatggcttttttaaaagagatttatgtatttggtaaatgtttgtagtcaacagttcacacaagaagctgtacacggtttgatcatgtaaaaccgtttggcggcacaagctggactttgttgccatccttgagatgaaccttttaagaaaaataagttaatctcaatttttccctgaatgtgttgtttttcttcattatacaataaatataatagtgaactttttatcaaatggtgaagacaatgctaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:4205 -> Molecular function: GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] evidence: IDA
GeneID:4205 -> Molecular function: GO:0000981 [sequence-specific DNA binding RNA polymerase II transcription factor activity] evidence: IDA
GeneID:4205 -> Molecular function: GO:0001077 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription] evidence: IEA
GeneID:4205 -> Molecular function: GO:0001085 [RNA polymerase II transcription factor binding] evidence: IPI
GeneID:4205 -> Molecular function: GO:0001105 [RNA polymerase II transcription coactivator activity] evidence: IDA
GeneID:4205 -> Molecular function: GO:0003682 [chromatin binding] evidence: IDA
GeneID:4205 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IDA
GeneID:4205 -> Molecular function: GO:0003705 [RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity] evidence: IEA
GeneID:4205 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:4205 -> Molecular function: GO:0019901 [protein kinase binding] evidence: IEA
GeneID:4205 -> Molecular function: GO:0033613 [activating transcription factor binding] evidence: IPI
GeneID:4205 -> Molecular function: GO:0035035 [histone acetyltransferase binding] evidence: IPI
GeneID:4205 -> Molecular function: GO:0042826 [histone deacetylase binding] evidence: IPI
GeneID:4205 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IDA
GeneID:4205 -> Molecular function: GO:0046332 [SMAD binding] evidence: IPI
GeneID:4205 -> Molecular function: GO:0046982 [protein heterodimerization activity] evidence: IPI
GeneID:4205 -> Biological process: GO:0000002 [mitochondrial genome maintenance] evidence: ISS
GeneID:4205 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:4205 -> Biological process: GO:0000165 [MAPK cascade] evidence: IDA
GeneID:4205 -> Biological process: GO:0002224 [toll-like receptor signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0002756 [MyD88-independent toll-like receptor signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IDA
GeneID:4205 -> Biological process: GO:0006366 [transcription from RNA polymerase II promoter] evidence: IDA
GeneID:4205 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:4205 -> Biological process: GO:0007507 [heart development] evidence: IEP
GeneID:4205 -> Biological process: GO:0007517 [muscle organ development] evidence: NAS
GeneID:4205 -> Biological process: GO:0034134 [toll-like receptor 2 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0034138 [toll-like receptor 3 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0034142 [toll-like receptor 4 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0034146 [toll-like receptor 5 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0034162 [toll-like receptor 9 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0034166 [toll-like receptor 10 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0035666 [TRIF-dependent toll-like receptor signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0042692 [muscle cell differentiation] evidence: TAS
GeneID:4205 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
GeneID:4205 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:4205 -> Biological process: GO:0048011 [neurotrophin TRK receptor signaling pathway] evidence: TAS
GeneID:4205 -> Biological process: GO:0048311 [mitochondrion distribution] evidence: ISS
GeneID:4205 -> Biological process: GO:0048813 [dendrite morphogenesis] evidence: ISS
GeneID:4205 -> Biological process: GO:0051149 [positive regulation of muscle cell differentiation] evidence: TAS
GeneID:4205 -> Biological process: GO:0051403 [stress-activated MAPK cascade] evidence: TAS
GeneID:4205 -> Biological process: GO:0055005 [ventricular cardiac myofibril assembly] evidence: ISS
GeneID:4205 -> Biological process: GO:0061337 [cardiac conduction] evidence: ISS
GeneID:4205 -> Biological process: GO:0070375 [ERK5 cascade] evidence: IMP
GeneID:4205 -> Biological process: GO:0071277 [cellular response to calcium ion] evidence: IDA
GeneID:4205 -> Cellular component: GO:0000790 [nuclear chromatin] evidence: ISS
GeneID:4205 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:4205 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.