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2024-04-27 10:06:18, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001130926            5481 bp    mRNA    linear   PRI 17-APR-2013
DEFINITION  Homo sapiens myocyte enhancer factor 2A (MEF2A), transcript variant
            2, mRNA.
ACCESSION   NM_001130926
VERSION     NM_001130926.1  GI:195972800
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5481)
  AUTHORS   Nitert,M.D., Dayeh,T., Volkov,P., Elgzyri,T., Hall,E., Nilsson,E.,
            Yang,B.T., Lang,S., Parikh,H., Wessman,Y., Weishaupt,H., Attema,J.,
            Abels,M., Wierup,N., Almgren,P., Jansson,P.A., Ronn,T., Hansson,O.,
            Eriksson,K.F., Groop,L. and Ling,C.
  TITLE     Impact of an exercise intervention on DNA methylation in skeletal
            muscle from first-degree relatives of patients with type 2 diabetes
  JOURNAL   Diabetes 61 (12), 3322-3332 (2012)
   PUBMED   23028138
  REMARK    GeneRIF: DNA methylation of genes in retinol metabolism and calcium
            signaling pathways (P < 3 x 10-6) and with known functions in
            muscle and T2D including MEF2A, RUNX1, NDUFC2, and THADA decreased
            after exercise
REFERENCE   2  (bases 1 to 5481)
  AUTHORS   Zhao,W., Zhao,S.P. and Peng,D.Q.
  TITLE     The effects of myocyte enhancer factor 2A gene on the
            proliferation, migration and phenotype of vascular smooth muscle
            cells
  JOURNAL   Cell Biochem. Funct. 30 (2), 108-113 (2012)
   PUBMED   22028303
  REMARK    GeneRIF: MEF2A dominant negative mutation enhanced cell
            proliferation and cell migration.
REFERENCE   3  (bases 1 to 5481)
  AUTHORS   Liu,Y., Niu,W., Wu,Z., Su,X., Chen,Q., Lu,L. and Jin,W.
  TITLE     Variants in exon 11 of MEF2A gene and coronary artery disease:
            evidence from a case-control study, systematic review, and
            meta-analysis
  JOURNAL   PLoS ONE 7 (2), E31406 (2012)
   PUBMED   22363637
  REMARK    GeneRIF: The rare 21-bp deletion might have a more compelling
            effect on coronary artery disease (CAD) than the common (CAG)(n)
            polymorphism, and MEF2A genetic variant might be a rare but
            specific cause of CAD/myocardial infarction.
            Review article
REFERENCE   4  (bases 1 to 5481)
  AUTHORS   Katsarou,K., Tsitoura,P. and Georgopoulou,U.
  TITLE     MEK5/ERK5/mef2: a novel signaling pathway affected by hepatitis C
            virus non-enveloped capsid-like particles
  JOURNAL   Biochim. Biophys. Acta 1813 (10), 1854-1862 (2011)
   PUBMED   21767578
  REMARK    GeneRIF: HCVne particles are capable of inducing the recently
            discovered ERK5 pathway, in a dose dependent way.
REFERENCE   5  (bases 1 to 5481)
  AUTHORS   She,H. and Mao,Z.
  TITLE     Regulation of myocyte enhancer factor-2 transcription factors by
            neurotoxins
  JOURNAL   Neurotoxicology 32 (5), 563-566 (2011)
   PUBMED   21741404
  REMARK    GeneRIF: [review] In this work, the mechanisms of regulation of
            MEF2 function by several well-known neurotoxins and their
            implications in various neurodegenerative diseases are reviewed.
            Review article
REFERENCE   6  (bases 1 to 5481)
  AUTHORS   Molkentin,J.D., Black,B.L., Martin,J.F. and Olson,E.N.
  TITLE     Cooperative activation of muscle gene expression by MEF2 and
            myogenic bHLH proteins
  JOURNAL   Cell 83 (7), 1125-1136 (1995)
   PUBMED   8548800
REFERENCE   7  (bases 1 to 5481)
  AUTHORS   Hobson,G.M., Krahe,R., Garcia,E., Siciliano,M.J. and Funanage,V.L.
  TITLE     Regional chromosomal assignments for four members of the MADS
            domain transcription enhancer factor 2 (MEF2) gene family to human
            chromosomes 15q26, 19p12, 5q14, and 1q12-q23
  JOURNAL   Genomics 29 (3), 704-711 (1995)
   PUBMED   8575763
REFERENCE   8  (bases 1 to 5481)
  AUTHORS   Funk,W.D. and Wright,W.E.
  TITLE     Cyclic amplification and selection of targets for multicomponent
            complexes: myogenin interacts with factors recognizing binding
            sites for basic helix-loop-helix, nuclear factor 1,
            myocyte-specific enhancer-binding factor 2, and COMP1 factor
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 89 (20), 9484-9488 (1992)
   PUBMED   1329097
REFERENCE   9  (bases 1 to 5481)
  AUTHORS   Yu,Y.T., Breitbart,R.E., Smoot,L.B., Lee,Y., Mahdavi,V. and
            Nadal-Ginard,B.
  TITLE     Human myocyte-specific enhancer factor 2 comprises a group of
            tissue-restricted MADS box transcription factors
  JOURNAL   Genes Dev. 6 (9), 1783-1798 (1992)
   PUBMED   1516833
REFERENCE   10 (bases 1 to 5481)
  AUTHORS   Pollock,R. and Treisman,R.
  TITLE     Human SRF-related proteins: DNA-binding properties and potential
            regulatory targets
  JOURNAL   Genes Dev. 5 (12A), 2327-2341 (1991)
   PUBMED   1748287
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA778137.1, Y16312.1,
            BC013437.2, AB208985.1, AC022692.11 and N93079.1.
            
            Summary: The protein encoded by this gene is a DNA-binding
            transcription factor that activates many muscle-specific, growth
            factor-induced, and stress-induced genes. The encoded protein can
            act as a homodimer or as a heterodimer and is involved in several
            cellular processes, including muscle development, neuronal
            differentiation, cell growth control, and apoptosis. Defects in
            this gene could be a cause of autosomal dominant coronary artery
            disease 1 with myocardial infarction (ADCAD1). Several transcript
            variants encoding different isoforms have been found for this
            gene.[provided by RefSeq, Jan 2010].
            
            Transcript Variant: This variant (2) uses an alternate coding exon,
            and is missing a 5' non-coding exon, compared to transcript variant
            1. This results in a shorter isoform (2) with a varied internal 43
            aa segment compared to isoform 1. Variants 2 and 5 both encode
            isoform 2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK291835.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025082, ERS025083 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-177               DA778137.1         1-177
            178-1179            Y16312.1           87-1088
            1180-1964           BC013437.2         1186-1970
            1965-2802           AB208985.1         2232-3069
            2803-5268           AC022692.11        153286-155751
            5269-5481           N93079.1           1-213               c
FEATURES             Location/Qualifiers
     source          1..5481
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q26"
     gene            1..5481
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /note="myocyte enhancer factor 2A"
                     /db_xref="GeneID:4205"
                     /db_xref="HGNC:6993"
                     /db_xref="MIM:600660"
     exon            1..177
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /inference="alignment:Splign:1.39.8"
     exon            178..373
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    311..313
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /note="upstream in-frame stop codon"
     CDS             320..1813
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /note="isoform 2 is encoded by transcript variant 2; MADS
                     box transcription enhancer factor 2, polypeptide A
                     (myocyte enhancer factor 2A); myocyte-specific enhancer
                     factor 2A; serum response factor-like protein 1"
                     /codon_start=1
                     /product="myocyte-specific enhancer factor 2A isoform 2"
                     /protein_id="NP_001124398.1"
                     /db_xref="GI:195972801"
                     /db_xref="CCDS:CCDS53978.1"
                     /db_xref="GeneID:4205"
                     /db_xref="HGNC:6993"
                     /db_xref="MIM:600660"
                     /translation="
MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNEDSDFIFKRGPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSMLSPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIGATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQQQPPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTEDRESPSVKRMRMDAWVT
"
     misc_feature    323..553
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /note="MEF2 (myocyte enhancer factor 2)-like/Type II
                     subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF
                     (serum response factor) box family of eukaryotic
                     transcriptional regulators. Binds DNA and exists as hetero
                     and homo-dimers. Differs from SRF-like/Type I...; Region:
                     MADS_MEF2_like; cd00265"
                     /db_xref="CDD:29020"
     misc_feature    order(323..331,335..337,341..343,356..358,362..364,
                     374..379,386..391,395..400,407..412,416..421,431..433)
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:29020"
     misc_feature    order(380..382,401..406,413..418,422..427,434..436,
                     449..451,455..457,461..463,479..481,485..487,503..505,
                     512..517,524..526,533..538)
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:29020"
     misc_feature    494..496
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /note="putative phosphorylation site [posttranslational
                     modification]; other site"
                     /db_xref="CDD:29020"
     misc_feature    602..778
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /note="Holliday junction regulator protein family
                     C-terminal repeat; Region: HJURP_C; pfam12347"
                     /db_xref="CDD:152782"
     STS             329..740
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /standard_name="Mef2a"
                     /db_xref="UniSTS:265600"
     STS             329..689
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /standard_name="Mef2a"
                     /db_xref="UniSTS:265601"
     variation       343
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370523988"
     exon            374..577
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /inference="alignment:Splign:1.39.8"
     variation       433
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191032083"
     variation       461
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:368747387"
     variation       484
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372436031"
     variation       487
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200687749"
     exon            578..709
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /inference="alignment:Splign:1.39.8"
     variation       578
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:17423081"
     variation       585
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:3205682"
     variation       600
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:368757733"
     variation       601
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1135555"
     variation       607
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1135556"
     variation       610
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1135557"
     variation       616
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1135558"
     variation       619
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1135559"
     variation       620
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1135560"
     variation       625
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1135561"
     variation       632
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1135562"
     variation       636
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:3208173"
     variation       642
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1135563"
     variation       649
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1136937"
     variation       652
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3198317"
     variation       655
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1135564"
     variation       658
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1135565"
     variation       664
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1135566"
     variation       666
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1135567"
     variation       667
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1135568"
     variation       671
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1135569"
     variation       679
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1135570"
     variation       684
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1135571"
     variation       689
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1135572"
     variation       690
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1135574"
     variation       705
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1135575"
     variation       709
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:17420057"
     exon            710..929
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /inference="alignment:Splign:1.39.8"
     variation       780
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374058145"
     variation       830
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:189538320"
     variation       832
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3803420"
     variation       865
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:146192119"
     variation       876
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:370083199"
     variation       911
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:373867888"
     exon            930..989
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /inference="alignment:Splign:1.39.8"
     variation       942
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199820037"
     variation       958
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376779827"
     variation       971
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:377207410"
     exon            990..1177
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /inference="alignment:Splign:1.39.8"
     variation       1056
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:189526729"
     variation       1070
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:199751824"
     variation       1075
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369943942"
     variation       1101
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:121918530"
     variation       1109
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:79454361"
     variation       1120
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200748600"
     variation       1147
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369552532"
     variation       1148
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373219260"
     variation       1149
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:121918529"
     variation       1161
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:121918531"
     variation       1174
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376183174"
     exon            1178..1304
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /inference="alignment:Splign:1.39.8"
     variation       1180..1181
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:17854846"
     variation       1180
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:325408"
     variation       1186
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:325407"
     variation       1225
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3730283"
     variation       1261
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372479689"
     variation       1283
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373204094"
     exon            1305..1431
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /inference="alignment:Splign:1.39.8"
     variation       1318
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:373943430"
     variation       1321
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368107439"
     variation       1322
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373128826"
     exon            1432..5467
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /inference="alignment:Splign:1.39.8"
     variation       1432
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199613639"
     variation       1461
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375108417"
     variation       1474
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369483642"
     STS             1491..1648
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /standard_name="G64293"
                     /db_xref="UniSTS:158672"
     variation       1527
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372533601"
     variation       1537
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144461661"
     variation       1539
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369579124"
     variation       1540
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:3730059"
     variation       1546..1547
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="cagcag"
                     /db_xref="dbSNP:374033278"
     variation       1547..1552
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="cagcag"
                     /db_xref="dbSNP:3138597"
     variation       1547..1549
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="cag"
                     /db_xref="dbSNP:373652230"
     variation       1551..1556
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="agcagc"
                     /db_xref="dbSNP:58424802"
     variation       1555..1560
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="gcagca"
                     /db_xref="dbSNP:72276751"
     variation       1556..1557
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="cagcag"
                     /db_xref="dbSNP:72236998"
     variation       1557..1558
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="agcagc"
                     /db_xref="dbSNP:72416294"
     variation       1563
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:200861006"
     variation       1566..1571
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="agcagc"
                     /db_xref="dbSNP:72198683"
     variation       1575
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201861701"
     variation       1578
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:199811207"
     variation       1584
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369815961"
     variation       1594
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367780642"
     variation       1642
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:325400"
     variation       1658
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:370921147"
     variation       1729
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:34851361"
     variation       1730
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:111748677"
     variation       1743
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370778860"
     variation       1958..1959
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="gtgt"
                     /db_xref="dbSNP:145618675"
     variation       1958
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:201277440"
     variation       1959..1960
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="gtgt"
                     /db_xref="dbSNP:144020290"
     variation       1960..1961
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="gtgt"
                     /db_xref="dbSNP:10628004"
     variation       1965..1966
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="gtgt"
                     /db_xref="dbSNP:34507751"
     variation       1965
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:28444186"
     variation       2005
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:374107493"
     variation       2052
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376220587"
     variation       2316
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:75665175"
     variation       2327
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140014502"
     variation       2339
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:72760574"
     variation       2381
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:190007997"
     variation       2388
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201784078"
     variation       2388
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:34756453"
     variation       2453
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:145205421"
     variation       2465
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11635271"
     STS             2468..2817
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /standard_name="D15S907"
                     /db_xref="UniSTS:279"
     variation       2678
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:182261693"
     variation       2829
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1059750"
     variation       2830
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:186608671"
     variation       2855
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1454315"
     variation       3005
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190999757"
     variation       3235..3239
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="gttaa"
                     /db_xref="dbSNP:71982844"
     variation       3242
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="aactt"
                     /db_xref="dbSNP:67611863"
     variation       3245
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1059755"
     variation       3246
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149125295"
     variation       3250
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1059756"
     variation       3256
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1059757"
     variation       3280..3281
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1059758"
     variation       3281
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:325399"
     variation       3286
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1136940"
     variation       3471
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142460833"
     variation       3472
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184041593"
     variation       3497
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368872347"
     variation       3562
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:897074"
     variation       3790
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:188542083"
     variation       3809
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372386338"
     variation       3841
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375267826"
     variation       3848
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:59420387"
     variation       3850
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:12902459"
     variation       3851..3852
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:67644135"
     variation       3852
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:58267790"
     variation       3854..3855
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="cc"
                     /db_xref="dbSNP:141367967"
     variation       3854
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:144314500"
     variation       3856
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:11550216"
     variation       3857
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:75869168"
     variation       3858
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:148429386"
     variation       3863
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="c"
                     /replace="cc"
                     /db_xref="dbSNP:58849948"
     variation       3871
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1059759"
     variation       3883
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:325383"
     variation       3941
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:325382"
     variation       4009
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1059760"
     variation       4022
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:11550217"
     variation       4027
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:193162969"
     variation       4046
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:184981047"
     variation       4049
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:187250165"
     variation       4132
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:372383636"
     variation       4189
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146891523"
     variation       4379
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191660882"
     variation       4488
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:41303617"
     variation       4569
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140716704"
     variation       4651
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:325381"
     variation       4652
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:200152842"
     variation       4670
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183911417"
     variation       4748
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:113970475"
     variation       4776
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:188188955"
     variation       4781
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:34602555"
     variation       4860
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:182321371"
     variation       4862
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113827147"
     variation       4902
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145829205"
     variation       4909..4910
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="cat"
                     /db_xref="dbSNP:374735275"
     variation       4909
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:77710130"
     variation       4910..4911
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace=""
                     /replace="atc"
                     /db_xref="dbSNP:371572866"
     variation       4929
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:28377673"
     variation       4943
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:138403437"
     variation       5054
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:74033759"
     STS             5192..5464
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /standard_name="D15S901"
                     /db_xref="UniSTS:13157"
     variation       5315
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150316263"
     variation       5377
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:12442844"
     polyA_site      5395
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
     polyA_signal    5419..5424
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
     polyA_site      5448
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
     variation       5455
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:325380"
     polyA_site      5467
                     /gene="MEF2A"
                     /gene_synonym="ADCAD1; mef2; RSRFC4; RSRFC9"
ORIGIN      
agaacgagttccggtctggccgaggcttgtctcctaaaaatagccccggtgtggggatccgtgcgcggatgtcccggcgagtcccgggctgaaagaggcggctccgggcggcgcgaagcgctggtggcgggcccgggctgcggcgtgtgcgcgcccgccagctgctccggagatacgatcttgtagaaaatttcagctgtagcccttggactagaagctgaaataacagaagctgtgtacgatgcattagggtattgaagaaaattaacttttgaattaaatatttggaatataaggaaataaggaaagttgactgaaaatggggcggaagaaaatacaaatcacacgcataatggatgaaaggaaccgacaggtcacttttacaaagagaaagtttggattaatgaagaaagcctatgaacttagtgtgctctgtgactgtgaaatagcactcatcattttcaacagctctaacaaactgtttcaatatgctagcactgatatggacaaagttcttctcaagtatacagaatataatgaacctcatgaaagcagaaccaactcggatattgttgagactttaagaaagaaaggccttaatggttgtgagagccctgatgctgacgattactttgagcacagtccactctcggaggacagattcagcaaactaaatgaagatagtgattttattttcaaacgaggccctcctggtctgccacctcagaacttttcaatgtctgtcacagttccagtgaccagccccaatgctttgtcctacactaacccagggagttcactggtgtccccatctttggcagccagctcaacgttaacagattcaagcatgctctctccacctcaaaccacattacatagaaatgtgtctcctggagctcctcagagaccaccaagtactggcaatgcaggtgggatgttgagcactacagacctcacagtgccaaatggagctggaagcagtccagtggggaatggatttgtaaactcaagagcttctccaaatttgattggagctactggtgcaaatagcttaggcaaagtcatgcctacaaagtctccccctccaccaggtggtggtaatcttggaatgaacagtaggaaaccagatcttcgagttgtcatccccccttcaagcaagggcatgatgcctccactaaatacccaaaggatcagtagttctcaagccactcaacctcttgctaccccagtcgtgtctgtgacaaccccaagcttgcctccgcaaggacttgtgtactcagcaatgccgactgcctacaacactgattattcactgaccagcgctgacctgtcagcccttcaaggcttcaactcgccaggaatgctgtcgctgggacaggtgtcggcctggcagcagcaccacctaggacaagcagccctcagctctcttgttgctggagggcagttatctcagggttccaatttatccattaataccaaccaaaacatcagcatcaagtccgaaccgatttcacctcctcgggatcgtatgaccccatcgggcttccagcagcagcagcagcagcagcagcagcagcagccgccgccaccaccgcagccccagccacaacccccgcagccccagccccgacaggaaatggggcgctcccctgtggacagtctgagcagctctagtagctcctatgatggcagtgatcgggaggatccacggggcgacttccattctccaattgtgcttggccgacccccaaacactgaggacagagaaagcccttctgtaaagcgaatgaggatggacgcgtgggtgacctaaggcttccaagctgatgtttgtacttttgtgttactgcagtgacctgccctacatatctaaatcggtaaataaggacatgagttaaatatatttatatgtacatacatatatatatccctttacatatatatgtatgtgggtgtgagtgtgtatgtgtgggtgtgtgttacatacacagaatcaggcacttacctgcaaactccttgtaggtctgcagatgtgtgtcccatggcagacaaagcaccctgtaggcacagacaagtctggcacttccttggactacttgtttcgtaaagataaccagtttttgcagagaaacgtgtacccatatataattctcccacactagcttgcagaaacctagagggccccctacttgttttatttaactgtgcagtgactgtagttacttaagagaaaatgctttgtagaacagagcagtagaaaagcaggaaccaagaaagcaatactgtacataaaatgtcatttatattttccaacctggcatgggtgtctgttgcaaaggggtgcatgggaaagggctgttgatattaaaaacaaacaaaacaaaaaagccccacacataactgttttgcacgtgcaaaaatgtattgggtcaagaagtgatctttagctaataaagaaagagaatagaaaacacgcatgagatattcagaaaatactagcctagaaatatagagcattaacaaagtaaaattaatatattaagttataattggaatatgtcagaagtttctttttacattcatatcttaaaaattaaagaaactgattttagctcatgtatattttatatgaaagaaaacacccttatgaattgatgactatatataaaattatattcactacttttgaacacattctgctatgaattatttatataagccaaagctatatgttgtaacttttttttagagaatagctttatcttggtttaactctttagttttattttaagaggggaaaacaaaaatatcttgcaagcagaaccttggaaaaaaaaagccatgaacacttattctaaatgtaaattaaaagttgagccaaactctttgtgtatatagcatcttaaatatattatcacctttgatgtaagtacctatgtattgtatggtcaccagattaaaaagtatatttttgtggattgccgccaatctggggggaaaaggcgaggtcctttattaagtattcactgtttaatatttactattttgttaaatatactgtactttggattttaattattagcccagttttttcagaggattgtataaaggggtttctcccctcactggtggtgaatgtgtgatgttacattgtaatctttgtgctgtatgggttgagcatcattatatattttgtatgtgtacataaatagcaaagtggcaaaaaaaattggtgttaagttcatcctgcataagtataaaatgtgttgtaacagattttgtaaggcattatttaaaacttgccttttgtgaggaaaaaatgtagtagaaaaagctgacctaatttaattaatattagagaaaatggcaaaatagtagatgagcacaaaggttttataagtggtaaatgattaggggaaaataatcatggggaaagggatcttttttccttgaccctctgaaaacagaacgatgcagctggttacaaaatcctaccgttatcagctcttctgcacattgcagtgatgctttggtatgcggggagaaacactcttagggtgctggtccttggcatgactcttgccattctaattggaattagtgccaccctcagcttggattttgaacaaggccttattctttcaggaagacaactaatggatgatagcaagttcatccacttactgggcttgtgccatgagcaaaattcaaagtcctgtatatctttcattgtagatttttaaatactccttttcctaaaaaactcaagggtttaaaaattgctattttatattttaaatgatattgagcagctacctacaatttctatgtacattttgttcccccccccccaccccccccccaaattacgttccttttgacattttcctcatctgctgtttgtgacaagtcatcagccagatttcctgactgacacataggtatgatcagtgcaggagagacctgcgcaccacaggctgcaaactggaggttctgttctcatggcagtttgggcagtaacttttgagagaggccaaaaaaaggaggatgacatgctgtctcctctcttcagtatagacattaggctcttattcagaaaggatttttctttaaaaatgtacttactttactgaactacttacaggcacatttcttcataaggccacacctaatccaaacaagacagtctcccaacactgaagttccaaaataatccttaccactttgtaaaccatttatagctttgaaagtgttaagtgattccttcgttattatttatgcatgttcatgaacttctgctgtacattggaataggagttaacacattcacatttactgtctattttcttgtgtgccttatgagatggcttttctgactgtatctcaatagtctttctttctatgcaggtttataatcagtacaactactgttttctaaaatactactactcaaggctcggagtttgtatttaaattacactgaccaagtaacaatgtattccatttcaggaactgaatatttgactgttaacctttttcccatacgtccagtgtggcatggagcatatggacttgacagacatctctcacccagacgcccacgtgtgaacacacccacatccacatctctgggtggaaaccagcctagagaggggacgacgctaatggtgttgctttagaaccgtcttttcttacccttttagactcgtgttttgtatgagacaccattgcaagaaaattttatccctccagaagtattttattactaaagaacaaaagcaaaaaaagcttaaattgcactggttaaagtacagtttccaacagctgtccttcctcagtactctaatggccactccaccgcgagtggaagtcactgttgtgtgtacacaggtggtcccaatcaaaactccatcttttgagcccaattatgtccattttgttatagactaaatcaggggtttgttctacaagaacaatacatgttttaccctttcctttaactagaaggataactagtaatgcatcaacataatttctgtattaaccatcatgcgcacaagaaatacatagtaaataaggaagctgaaaactcctggcattggatcttaagctagatgattagaatgtgaaaaagattttacaaatgtaaaacttctatttctctgtagaaactttcttcactttgctgtgcaagaagacactgctttgctatatttaaaatggcttttttaaaagagatttatgtatttggtaaatgtttgtagtcaacagttcacacaagaagctgtacacggtttgatcatgtaaaaccgtttggcggcacaagctggactttgttgccatccttgagatgaaccttttaagaaaaataagttaatctcaatttttccctgaatgtgttgtttttcttcattatacaataaatataatagtgaactttttatcaaatggtgaagacaatgctaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:4205 -> Molecular function: GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding] evidence: IDA
            GeneID:4205 -> Molecular function: GO:0000981 [sequence-specific DNA binding RNA polymerase II transcription factor activity] evidence: IDA
            GeneID:4205 -> Molecular function: GO:0001077 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription] evidence: IEA
            GeneID:4205 -> Molecular function: GO:0001085 [RNA polymerase II transcription factor binding] evidence: IPI
            GeneID:4205 -> Molecular function: GO:0001105 [RNA polymerase II transcription coactivator activity] evidence: IDA
            GeneID:4205 -> Molecular function: GO:0003682 [chromatin binding] evidence: IDA
            GeneID:4205 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IDA
            GeneID:4205 -> Molecular function: GO:0003705 [RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity] evidence: IEA
            GeneID:4205 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:4205 -> Molecular function: GO:0019901 [protein kinase binding] evidence: IEA
            GeneID:4205 -> Molecular function: GO:0033613 [activating transcription factor binding] evidence: IPI
            GeneID:4205 -> Molecular function: GO:0035035 [histone acetyltransferase binding] evidence: IPI
            GeneID:4205 -> Molecular function: GO:0042826 [histone deacetylase binding] evidence: IPI
            GeneID:4205 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IDA
            GeneID:4205 -> Molecular function: GO:0046332 [SMAD binding] evidence: IPI
            GeneID:4205 -> Molecular function: GO:0046982 [protein heterodimerization activity] evidence: IPI
            GeneID:4205 -> Biological process: GO:0000002 [mitochondrial genome maintenance] evidence: ISS
            GeneID:4205 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IDA
            GeneID:4205 -> Biological process: GO:0000165 [MAPK cascade] evidence: IDA
            GeneID:4205 -> Biological process: GO:0002224 [toll-like receptor signaling pathway] evidence: TAS
            GeneID:4205 -> Biological process: GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] evidence: TAS
            GeneID:4205 -> Biological process: GO:0002756 [MyD88-independent toll-like receptor signaling pathway] evidence: TAS
            GeneID:4205 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IDA
            GeneID:4205 -> Biological process: GO:0006366 [transcription from RNA polymerase II promoter] evidence: IDA
            GeneID:4205 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
            GeneID:4205 -> Biological process: GO:0007507 [heart development] evidence: IEP
            GeneID:4205 -> Biological process: GO:0007517 [muscle organ development] evidence: NAS
            GeneID:4205 -> Biological process: GO:0034134 [toll-like receptor 2 signaling pathway] evidence: TAS
            GeneID:4205 -> Biological process: GO:0034138 [toll-like receptor 3 signaling pathway] evidence: TAS
            GeneID:4205 -> Biological process: GO:0034142 [toll-like receptor 4 signaling pathway] evidence: TAS
            GeneID:4205 -> Biological process: GO:0034146 [toll-like receptor 5 signaling pathway] evidence: TAS
            GeneID:4205 -> Biological process: GO:0034162 [toll-like receptor 9 signaling pathway] evidence: TAS
            GeneID:4205 -> Biological process: GO:0034166 [toll-like receptor 10 signaling pathway] evidence: TAS
            GeneID:4205 -> Biological process: GO:0035666 [TRIF-dependent toll-like receptor signaling pathway] evidence: TAS
            GeneID:4205 -> Biological process: GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] evidence: TAS
            GeneID:4205 -> Biological process: GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] evidence: TAS
            GeneID:4205 -> Biological process: GO:0042692 [muscle cell differentiation] evidence: TAS
            GeneID:4205 -> Biological process: GO:0045087 [innate immune response] evidence: TAS
            GeneID:4205 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IDA
            GeneID:4205 -> Biological process: GO:0048011 [neurotrophin TRK receptor signaling pathway] evidence: TAS
            GeneID:4205 -> Biological process: GO:0048311 [mitochondrion distribution] evidence: ISS
            GeneID:4205 -> Biological process: GO:0048813 [dendrite morphogenesis] evidence: ISS
            GeneID:4205 -> Biological process: GO:0051149 [positive regulation of muscle cell differentiation] evidence: TAS
            GeneID:4205 -> Biological process: GO:0051403 [stress-activated MAPK cascade] evidence: TAS
            GeneID:4205 -> Biological process: GO:0055005 [ventricular cardiac myofibril assembly] evidence: ISS
            GeneID:4205 -> Biological process: GO:0061337 [cardiac conduction] evidence: ISS
            GeneID:4205 -> Biological process: GO:0070375 [ERK5 cascade] evidence: IMP
            GeneID:4205 -> Biological process: GO:0071277 [cellular response to calcium ion] evidence: IDA
            GeneID:4205 -> Cellular component: GO:0000790 [nuclear chromatin] evidence: ISS
            GeneID:4205 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
            GeneID:4205 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS

by @meso_cacase at DBCLS
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