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2024-04-20 01:00:58, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001128853 3020 bp mRNA linear PRI 07-JUL-2013
DEFINITION Homo sapiens serrate RNA effector molecule homolog (Arabidopsis)
(SRRT), transcript variant 4, mRNA.
ACCESSION NM_001128853
VERSION NM_001128853.1 GI:192807333
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3020)
AUTHORS He,Q., Cai,L., Shuai,L., Li,D., Wang,C., Liu,Y., Li,X., Li,Z. and
Wang,S.
TITLE Ars2 is overexpressed in human cholangiocarcinomas and its
depletion increases PTEN and PDCD4 by decreasing microRNA-21
JOURNAL Mol. Carcinog. 52 (4), 286-296 (2013)
PUBMED 22213145
REMARK GeneRIF: Ars2 is overexpressed in human cholangiocarcinoma and may
be a diagnostic marker. Ars2 depletion increases PTEN and PDCD4
protein levels via the reduction of miR-21.
REFERENCE 2 (bases 1 to 3020)
AUTHORS Huang J, Sabater-Lleal M, Asselbergs FW, Tregouet D, Shin SY, Ding
J, Baumert J, Oudot-Mellakh T, Folkersen L, Johnson AD, Smith NL,
Williams SM, Ikram MA, Kleber ME, Becker DM, Truong V, Mychaleckyj
JC, Tang W, Yang Q, Sennblad B, Moore JH, Williams FM, Dehghan A,
Silbernagel G, Schrijvers EM, Smith S, Karakas M, Tofler GH,
Silveira A, Navis GJ, Lohman K, Chen MH, Peters A, Goel A, Hopewell
JC, Chambers JC, Saleheen D, Lundmark P, Psaty BM, Strawbridge RJ,
Boehm BO, Carter AM, Meisinger C, Peden JF, Bis JC, McKnight B,
Ohrvik J, Taylor K, Franzosi MG, Seedorf U, Collins R,
Franco-Cereceda A, Syvanen AC, Goodall AH, Yanek LR, Cushman M,
Muller-Nurasyid M, Folsom AR, Basu S, Matijevic N, van Gilst WH,
Kooner JS, Hofman A, Danesh J, Clarke R, Meigs JB, Kathiresan S,
Reilly MP, Klopp N, Harris TB, Winkelmann BR, Grant PJ, Hillege HL,
Watkins H, Spector TD, Becker LC, Tracy RP, Marz W, Uitterlinden
AG, Eriksson P, Cambien F, Morange PE, Koenig W, Soranzo N, van der
Harst P, Liu Y, O'Donnell CJ and Hamsten A.
CONSRTM DIAGRAM Consortium; CARDIoGRAM Consortium; C4D Consortium;
CARDIOGENICS Consortium
TITLE Genome-wide association study for circulating levels of PAI-1
provides novel insights into its regulation
JOURNAL Blood 120 (24), 4873-4881 (2012)
PUBMED 22990020
REFERENCE 3 (bases 1 to 3020)
AUTHORS Gruber,J.J., Olejniczak,S.H., Yong,J., La Rocca,G., Dreyfuss,G. and
Thompson,C.B.
TITLE Ars2 promotes proper replication-dependent histone mRNA 3' end
formation
JOURNAL Mol. Cell 45 (1), 87-98 (2012)
PUBMED 22244333
REMARK GeneRIF: Ars2 contributes to histone mRNA 3' end formation and
expression and these functional properties of Ars2 are negatively
regulated by interaction with 7SK RNA.
REFERENCE 4 (bases 1 to 3020)
AUTHORS Eijgelsheim,M., Newton-Cheh,C., Sotoodehnia,N., de Bakker,P.I.,
Muller,M., Morrison,A.C., Smith,A.V., Isaacs,A., Sanna,S., Dorr,M.,
Navarro,P., Fuchsberger,C., Nolte,I.M., de Geus,E.J., Estrada,K.,
Hwang,S.J., Bis,J.C., Ruckert,I.M., Alonso,A., Launer,L.J.,
Hottenga,J.J., Rivadeneira,F., Noseworthy,P.A., Rice,K.M., Perz,S.,
Arking,D.E., Spector,T.D., Kors,J.A., Aulchenko,Y.S., Tarasov,K.V.,
Homuth,G., Wild,S.H., Marroni,F., Gieger,C., Licht,C.M.,
Prineas,R.J., Hofman,A., Rotter,J.I., Hicks,A.A., Ernst,F.,
Najjar,S.S., Wright,A.F., Peters,A., Fox,E.R., Oostra,B.A.,
Kroemer,H.K., Couper,D., Volzke,H., Campbell,H., Meitinger,T.,
Uda,M., Witteman,J.C., Psaty,B.M., Wichmann,H.E., Harris,T.B.,
Kaab,S., Siscovick,D.S., Jamshidi,Y., Uitterlinden,A.G.,
Folsom,A.R., Larson,M.G., Wilson,J.F., Penninx,B.W., Snieder,H.,
Pramstaller,P.P., van Duijn,C.M., Lakatta,E.G., Felix,S.B.,
Gudnason,V., Pfeufer,A., Heckbert,S.R., Stricker,B.H.,
Boerwinkle,E. and O'Donnell,C.J.
TITLE Genome-wide association analysis identifies multiple loci related
to resting heart rate
JOURNAL Hum. Mol. Genet. 19 (19), 3885-3894 (2010)
PUBMED 20639392
REFERENCE 5 (bases 1 to 3020)
AUTHORS Gruber,J.J., Zatechka,D.S., Sabin,L.R., Yong,J., Lum,J.J., Kong,M.,
Zong,W.X., Zhang,Z., Lau,C.K., Rawlings,J., Cherry,S., Ihle,J.N.,
Dreyfuss,G. and Thompson,C.B.
TITLE Ars2 links the nuclear cap-binding complex to RNA interference and
cell proliferation
JOURNAL Cell 138 (2), 328-339 (2009)
PUBMED 19632182
REMARK GeneRIF: These findings provide evidence for a role for Ars2 in RNA
interference regulation during cell proliferation.
REFERENCE 6 (bases 1 to 3020)
AUTHORS Beausoleil,S.A., Jedrychowski,M., Schwartz,D., Elias,J.E.,
Villen,J., Li,J., Cohn,M.A., Cantley,L.C. and Gygi,S.P.
TITLE Large-scale characterization of HeLa cell nuclear phosphoproteins
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)
PUBMED 15302935
REFERENCE 7 (bases 1 to 3020)
AUTHORS Obuse,C., Yang,H., Nozaki,N., Goto,S., Okazaki,T. and Yoda,K.
TITLE Proteomics analysis of the centromere complex from HeLa interphase
cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of
the CEN-complex, while BMI-1 is transiently co-localized with the
centromeric region in interphase
JOURNAL Genes Cells 9 (2), 105-120 (2004)
PUBMED 15009096
REFERENCE 8 (bases 1 to 3020)
AUTHORS Di,Y., Li,J., Zhang,Y., He,X., Lu,H., Xu,D., Ling,J., Huo,K.,
Wan,D., Li,Y.Y. and Gu,J.
TITLE HCC-associated protein HCAP1, a variant of GEMIN4, interacts with
zinc-finger proteins
JOURNAL J. Biochem. 133 (6), 713-718 (2003)
PUBMED 12869526
REFERENCE 9 (bases 1 to 3020)
AUTHORS Wilson,M.D., Riemer,C., Martindale,D.W., Schnupf,P., Boright,A.P.,
Cheung,T.L., Hardy,D.M., Schwartz,S., Scherer,S.W., Tsui,L.C.,
Miller,W. and Koop,B.F.
TITLE Comparative analysis of the gene-dense ACHE/TFR2 region on human
chromosome 7q22 with the orthologous region on mouse chromosome 5
JOURNAL Nucleic Acids Res. 29 (6), 1352-1365 (2001)
PUBMED 11239002
REFERENCE 10 (bases 1 to 3020)
AUTHORS Rossman,T.G. and Wang,Z.
TITLE Expression cloning for arsenite-resistance resulted in isolation of
tumor-suppressor fau cDNA: possible involvement of the ubiquitin
system in arsenic carcinogenesis
JOURNAL Carcinogenesis 20 (2), 311-316 (1999)
PUBMED 10069470
REMARK GeneRIF: Nomenclature. Original paper and GenBank submission by
Rossman and Wang (1999) called the gene Asr2 (arsenite resistance
protein 2) as opposed to Ars2 (arsenate resistance protein 2).
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
DA611314.1, AF248955.1 and BC109117.1.
Transcript Variant: This variant (4) uses an alternate in-frame
splice junction at the end of a 3' exon compared to variant 1. The
resulting isoform (d) has the same N- and C-termini but is 4 aa
shorter compared to isoform a.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AF248955.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025082 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-126 DA611314.1 2-127
127-579 AF248955.1 89-541
580-1175 BC109117.1 474-1069
1176-3020 AF248955.1 1139-2983
FEATURES Location/Qualifiers
source 1..3020
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="7"
/map="7q21"
gene 1..3020
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/note="serrate RNA effector molecule homolog
(Arabidopsis)"
/db_xref="GeneID:51593"
/db_xref="HGNC:24101"
/db_xref="MIM:614469"
exon 1..250
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 91
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:190483545"
variation 94
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="g"
/db_xref="dbSNP:112883283"
variation 126
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:7789085"
variation 180
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="c"
/db_xref="dbSNP:112408737"
variation 232..234
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace=""
/replace="g"
/db_xref="dbSNP:11405482"
exon 251..390
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 255
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:374303554"
CDS 269..2887
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/note="isoform d is encoded by transcript variant 4;
arsenite resistance protein; arsenate resistance protein
ARS2; arsenate resistance protein 2; arsenite-resistance
protein 2"
/codon_start=1
/product="serrate RNA effector molecule homolog isoform d"
/protein_id="NP_001122325.1"
/db_xref="GI:192807334"
/db_xref="CCDS:CCDS47665.1"
/db_xref="GeneID:51593"
/db_xref="HGNC:24101"
/db_xref="MIM:614469"
/translation="
MGDSDDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRERFSPPRHELSPPQKRMRRDWDEHSSDPYHSGYEMPYAGGGGGPTYGPPQPWGHPDVHIMQHHVLPIQARLGSIAEIDLGVPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRILEQEEEEEQAGKPGEPSKKEEGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEEWEKPKDAAGLECKPRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLGSSGGAPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPMPPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQSLTPGLPYPHQTPQGLMPYGQPRPPILGYGAGAVRPAVPTGGPPYPHAPYGAGRGNYDAFRGQGGYPGKPRNRMVRGDPRAIVEYRDLDAPDDVDFF
"
misc_feature 719..1060
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/note="Domain of unknown function (DUF3546); Region:
DUF3546; pfam12066"
/db_xref="CDD:192930"
misc_feature 2174..2827
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/note="Arsenite-resistance protein 2; Region: ARS2;
pfam04959"
/db_xref="CDD:191139"
variation 298
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:73714208"
variation 337
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:140220881"
exon 391..519
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 469
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:150301770"
variation 481
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="c"
/db_xref="dbSNP:9735"
variation 493
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:11983638"
variation 513
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:199587931"
variation 516
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:149641563"
exon 520..666
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 577
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:201842398"
variation 600
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:374549725"
variation 625
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:144415744"
variation 628
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="g"
/db_xref="dbSNP:139233965"
exon 667..855
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 739
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:143241109"
variation 753
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:368922844"
variation 759
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:200061976"
variation 772
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:374407676"
variation 793
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:147475982"
variation 838
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:144725595"
variation 840
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:139994743"
exon 856..1025
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 883
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:145327657"
variation 893
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:370731717"
variation 894
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:150615307"
variation 908
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:201998782"
STS 965..1046
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/standard_name="GDB:4585149"
/db_xref="UniSTS:82221"
variation 965
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="g"
/replace="t"
/db_xref="dbSNP:201173432"
variation 974
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="g"
/db_xref="dbSNP:139718904"
variation 986
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:149954299"
variation 988
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="c"
/db_xref="dbSNP:112840274"
variation 996
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:201947936"
variation 1001
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="g"
/replace="t"
/db_xref="dbSNP:140988239"
variation 1011
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:143401742"
exon 1026..1210
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 1027
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:143459147"
variation 1056
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:368044223"
variation 1063
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:15624"
variation 1087
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="g"
/db_xref="dbSNP:80278106"
variation 1119
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:371531627"
variation 1123
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:376597506"
variation 1131
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:370063149"
variation 1139
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:150930514"
variation 1148
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:372442352"
variation 1160
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:373668899"
variation 1165
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="g"
/replace="t"
/db_xref="dbSNP:199702658"
variation 1166
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:375882161"
variation 1167
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:140745082"
variation 1177
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:116129589"
variation 1201
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:372411794"
variation 1202
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:139372604"
exon 1211..1309
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 1248
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="c"
/db_xref="dbSNP:143173043"
variation 1267
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:201815722"
variation 1285
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="c"
/db_xref="dbSNP:147090333"
exon 1310..1427
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 1345
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:375749738"
variation 1357
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:370145921"
variation 1363
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:200146086"
variation 1396
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:138346691"
variation 1415
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:149587305"
variation 1422
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="c"
/db_xref="dbSNP:199680289"
exon 1428..1585
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 1434
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:113298167"
variation 1435
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:376935428"
variation 1482
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="c"
/db_xref="dbSNP:144305791"
variation 1489
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:148712422"
variation 1501
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:141430834"
variation 1511
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:201256411"
variation 1512
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:150582291"
variation 1516
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:139980891"
variation 1560
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:200449232"
variation 1582
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="c"
/db_xref="dbSNP:143335283"
exon 1586..1647
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 1633
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:375704625"
exon 1648..1726
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 1672
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="g"
/db_xref="dbSNP:371307249"
exon 1727..1915
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 1747
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:140010363"
variation 1772
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:372466447"
variation 1782
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:149902453"
variation 1785
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:369901340"
variation 1786
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:201817694"
variation 1791
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:144966688"
variation 1804
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="g"
/db_xref="dbSNP:149025559"
variation 1822
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="g"
/db_xref="dbSNP:149979693"
variation 1870
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:200877158"
variation 1902
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:147945684"
exon 1916..2089
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 1936
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="g"
/db_xref="dbSNP:370769694"
variation 1944
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:373662262"
variation 1954
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:367847663"
variation 2000
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:200083178"
variation 2002
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:141861227"
variation 2005
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:376494688"
variation 2008
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:147125775"
variation 2015
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="g"
/db_xref="dbSNP:367936513"
variation 2061
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:372260164"
variation 2062
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:374859265"
variation 2064
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="g"
/replace="t"
/db_xref="dbSNP:28729265"
variation 2069
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:201528871"
variation 2086
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="t"
/db_xref="dbSNP:201215771"
variation 2088
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="c"
/db_xref="dbSNP:201941018"
exon 2090..2243
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 2143
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:373796549"
variation 2164
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:142458683"
variation 2200
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:141963166"
variation 2201
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:150212900"
exon 2244..2437
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 2292
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:371902746"
variation 2298
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:368050045"
variation 2368
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:371458309"
variation 2411
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="g"
/replace="t"
/db_xref="dbSNP:79048795"
variation 2419
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="g"
/db_xref="dbSNP:376598941"
exon 2438..2594
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 2461
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:201502804"
variation 2509
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:371033958"
variation 2510
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:199528372"
variation 2511
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:138829624"
variation 2545
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="g"
/db_xref="dbSNP:149342215"
variation 2581
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:146305624"
exon 2595..2684
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 2597
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="g"
/replace="t"
/db_xref="dbSNP:111916727"
variation 2642
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:113682842"
variation 2650
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:139947416"
variation 2671
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:141849947"
exon 2685..2811
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 2691
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:376557679"
variation 2709
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:146285121"
variation 2721
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:200680733"
variation 2740
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="g"
/replace="t"
/db_xref="dbSNP:148451475"
STS 2757..3004
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/standard_name="WI-20788"
/db_xref="UniSTS:78436"
variation 2769
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="g"
/db_xref="dbSNP:142627875"
variation 2787
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="g"
/replace="t"
/db_xref="dbSNP:369963076"
variation 2796
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="g"
/replace="t"
/db_xref="dbSNP:150948431"
variation 2804
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:139519950"
exon 2812..3002
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/inference="alignment:Splign:1.39.8"
variation 2827
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:11171"
STS 2837..2955
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/standard_name="GDB:4585547"
/db_xref="UniSTS:78827"
variation 2845
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:370307936"
variation 2869
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:368786443"
variation 2875
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="t"
/db_xref="dbSNP:2733917"
variation 2896
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:373699519"
variation 2909
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="t"
/db_xref="dbSNP:375567360"
variation 2933
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="c"
/replace="g"
/db_xref="dbSNP:368720237"
variation 2941
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:202030567"
variation 2952
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="g"
/db_xref="dbSNP:185805997"
variation 2966
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="g"
/replace="t"
/db_xref="dbSNP:114922826"
variation 2997
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="a"
/replace="c"
/db_xref="dbSNP:3178268"
variation 3002
/gene="SRRT"
/gene_synonym="ARS2; ASR2; serrate"
/replace="g"
/replace="t"
/db_xref="dbSNP:137910416"
ORIGIN
agttccagttccggccgcgagggtggagctttgtgcctcggaggcgtgggtgacgcaggcgcagcgcgggctgcgcgcgctactgcccatccccggttgtcccacttttgttcgcctctcttcggccctctactcaagagctccgtctccgtctcgccctcctcgaagtcctcgtcgcgcgcccgcgacccaggtcgccctgaaatctagcccgtccgagcgcgagtccaacggccgcggccgcaccaaggccccctcagaccgtgccatgggtgacagtgatgacgagtacgatcgaaggcgcagggacaagttcagaagagagcgcagcgactacgaccgttcccgcgagagagatgaaagacgtcgaggggacgattggaatgacagagagtgggaccgtggccgtgagcgccgtagtcggggtgaatatcgggactatgaccggaatcggcgagagcgcttctcgccacctcgccacgaactcagcccgccacagaagcgcatgaggagagactgggatgagcacagctctgacccataccacagtggctatgagatgccctatgctggggggggtgggggcccaacttatggcccccctcagccctggggccaccctgacgtccacatcatgcagcaccatgtcctgcctatccaggccaggctgggcagcattgcagagattgacctgggtgtgccgccgcccgtgatgaagaccttcaaggagtttctcctctccctggatgactcggtggatgagacggaggccgtcaagcgctataatgactacaagctggatttccggaggcaacagatgcaggatttcttcctggcgcacaaagatgaggagtggtttcggtctaagtaccacccagatgaggtggggaagcgtcggcaggaggcccggggggccctgcaaaaccgactgagggtcttcctgtccctcatggagactggctggtttgataaccttctcctggacatagacaaagctgatgccattgtcaagatgctggatgcagccgtgattaagatggaaggaggcacggagaatgatcttcgcatcctggagcaggaggaggaggaggagcaggcaggaaagcctggggagcccagcaagaaagaagaaggacgggctggagcaggcctaggggacggggagcgcaaaaccaacgacaaggatgagaagaaggaagacggcaagcaggctgagaatgacagttctaatgatgacaaaacaaagaagtcggagggtgatggggacaaggaagagaagaaagaagactccgagaaggaagccaaaaagagtagcaagaagcggaaccggaagcacagtggtgacgacagctttgacgagggcagcgtgtcagagtctgagtcggagtcagagagcggccaggctgaggaggagaaggaggaggccgaagaagcgctcaaggagaaggagaagcccaaggaagaagaatgggagaagcccaaggacgccgcggggctggagtgcaagccgcggccgctgcataagacctgctccctcttcatgcgcaacatcgcgcccaacatctcccgggccgagatcatctccctttgtaaaaggtacccaggctttatgcgggtggcgctctcagagccccagccagagaggaggtttttccgtcgtggctgggtgaccttcgaccgcagtgttaacattaaagagatctgttggaacctgcagaacatccgtctccgggagtgtgagctgagccctggtgtgaacagggacctgacccggcgcgttcgcaacatcaacggcatcacccagcacaagcagattgtgcgcaacgacatcaagctggcggccaagctgatccacacgctggatgacaggacacagctttgggcctcagaaccagggacgcctcccctgcccacgagcctgccctcgcaaaacccgatcttgaagaatatcaccgactacctgatcgaggaagtaagcgccgaggaggaggagctgctggggagcagcgggggcgctcctcctgaggagcctcctaaggaagggaacccggcagagatcaacgtggagcgggatgagaagttgattaaggtcttggacaagctcctcctttacctgcgcatcgtgcattccttggattattacaacacctgtgagtaccccaacgaggacgagatgcccaatcgctgtgggatcatccacgttcgggggcccatgccacccaaccgcatcagtcacggggaagtgctggagtggcagaagacttttgaggagaagctcacgccgttgctgagtgtgcgggagtcactctcagaggaagaggcccagaagatggggcgcaaagacccagagcaggaagtggagaagttcgtcacctccaacacgcaggaactgggcaaggataagtggctgtgtcctctcagtggcaagaaattcaagggtcctgagtttgtgcgcaaacatatcttcaacaagcatgcagagaaaattgaggaagtgaaaaaggaagtcgcgttttttaacaacttcctcactgatgctaagcgcccagctctgcctgagatcaagccagcccagccacctggccccgcccagagtttgaccccaggactcccctacccacaccagactccccagggcctgatgccctatggtcagccccggcccccgatcttgggctatggagctggtgctgtccgccctgcagtccccacaggaggccctccatacccccatgccccgtatggtgctggtcgagggaactatgatgccttccgaggccagggaggttatcctgggaaacctcgcaacaggatggttcgtggagacccaagggccattgtggaatatcgggacctggatgccccagacgatgttgatttcttttgagccgtcccccgttcctcagtcctgtatcatccatacttgtactaccttgtcctatgaagctctgagaattttttgtacgatcagccttactgctaataaaagcacttccacagggaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:51593 -> Molecular function: GO:0003677 [DNA binding] evidence: ISS
GeneID:51593 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:51593 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA
GeneID:51593 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: ISS
GeneID:51593 -> Biological process: GO:0008283 [cell proliferation] evidence: ISS
GeneID:51593 -> Biological process: GO:0031053 [primary miRNA processing] evidence: IMP
GeneID:51593 -> Biological process: GO:0046685 [response to arsenic-containing substance] evidence: NAS
GeneID:51593 -> Biological process: GO:0097150 [neuronal stem cell maintenance] evidence: ISS
GeneID:51593 -> Cellular component: GO:0005654 [nucleoplasm] evidence: ISS
GeneID:51593 -> Cellular component: GO:0005737 [cytoplasm] evidence: ISS
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.