Home |
Help |
Advanced search
2024-04-20 17:58:14, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001128826 4878 bp mRNA linear PRI 29-JUN-2013
DEFINITION Homo sapiens neuronal calcium sensor 1 (NCS1), transcript variant
2, mRNA.
ACCESSION NM_001128826
VERSION NM_001128826.1 GI:192447422
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4878)
AUTHORS Sherva,R., Tripodis,Y., Bennett,D.A., Chibnik,L.B., Crane,P.K., de
Jager,P.L., Farrer,L.A., Saykin,A.J., Shulman,J.M. and Green,R.C.
CONSRTM The GENAROADS Consortium, and The Alzheimer's Disease Neuroimaging
Initiative
TITLE Genome-wide association study of the rate of cognitive decline in
Alzheimer's disease
JOURNAL Alzheimers Dement (2013) In press
PUBMED 23535033
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 4878)
AUTHORS Multani,P.K., Clarke,T.K., Narasimhan,S., Ambrose-Lanci,L.,
Kampman,K.M., Pettinati,H.M., Oslin,D.W., O'Brien,C.P.,
Berrettini,W.H. and Lohoff,F.W.
TITLE Neuronal calcium sensor-1 and cocaine addiction: a genetic
association study in African-Americans and European Americans
JOURNAL Neurosci. Lett. 531 (1), 46-51 (2012)
PUBMED 22999924
REMARK GeneRIF: data suggest that genetic variants in the NCS-1 gene
contribute to susceptibility of Cocaine Abuse in individuals of
African descent.
REFERENCE 3 (bases 1 to 4878)
AUTHORS Heidarsson,P.O., Bjerrum-Bohr,I.J., Jensen,G.A., Pongs,O.,
Finn,B.E., Poulsen,F.M. and Kragelund,B.B.
TITLE The C-terminal tail of human neuronal calcium sensor 1 regulates
the conformational stability of the Ca(2)(+)(-) activated state
JOURNAL J. Mol. Biol. 417 (1-2), 51-64 (2012)
PUBMED 22227393
REMARK GeneRIF: the C-terminal tail is important for regulating the
conformational stability of NCS1 in Ca(2+)-activated state
REFERENCE 4 (bases 1 to 4878)
AUTHORS Woll,M.P., De Cotiis,D.A., Bewley,M.C., Tacelosky,D.M., Levenson,R.
and Flanagan,J.M.
TITLE Interaction between the D2 dopamine receptor and neuronal calcium
sensor-1 analyzed by fluorescence anisotropy
JOURNAL Biochemistry 50 (41), 8780-8791 (2011)
PUBMED 21875085
REMARK GeneRIF: analysis of the interaction between the D2 dopamine
receptor and neuronal calcium sensor-1
REFERENCE 5 (bases 1 to 4878)
AUTHORS Benbow,J.H., DeGray,B. and Ehrlich,B.E.
TITLE Protection of neuronal calcium sensor 1 protein in cells treated
with paclitaxel
JOURNAL J. Biol. Chem. 286 (40), 34575-34582 (2011)
PUBMED 21808066
REMARK GeneRIF: it is possible to protect cells from paclitaxel-induced
degradation of NCS-1 by inhibiting calpain activity
REFERENCE 6 (bases 1 to 4878)
AUTHORS Chen,C., Yu,L., Zhang,P., Jiang,J., Zhang,Y., Chen,X., Wu,Q., Wu,Q.
and Zhao,S.
TITLE Human neuronal calcium sensor-1 shows the highest expression level
in cerebral cortex
JOURNAL Neurosci. Lett. 319 (2), 67-70 (2002)
PUBMED 11825672
REFERENCE 7 (bases 1 to 4878)
AUTHORS Zhao,X., Varnai,P., Tuymetova,G., Balla,A., Toth,Z.E.,
Oker-Blom,C., Roder,J., Jeromin,A. and Balla,T.
TITLE Interaction of neuronal calcium sensor-1 (NCS-1) with
phosphatidylinositol 4-kinase beta stimulates lipid kinase activity
and affects membrane trafficking in COS-7 cells
JOURNAL J. Biol. Chem. 276 (43), 40183-40189 (2001)
PUBMED 11526106
REFERENCE 8 (bases 1 to 4878)
AUTHORS Nakamura,T.Y., Pountney,D.J., Ozaita,A., Nandi,S., Ueda,S., Rudy,B.
and Coetzee,W.A.
TITLE A role for frequenin, a Ca2+-binding protein, as a regulator of Kv4
K+-currents
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 98 (22), 12808-12813 (2001)
PUBMED 11606724
REFERENCE 9 (bases 1 to 4878)
AUTHORS Bourne,Y., Dannenberg,J., Pollmann,V., Marchot,P. and Pongs,O.
TITLE Immunocytochemical localization and crystal structure of human
frequenin (neuronal calcium sensor 1)
JOURNAL J. Biol. Chem. 276 (15), 11949-11955 (2001)
PUBMED 11092894
REFERENCE 10 (bases 1 to 4878)
AUTHORS Burgoyne,R.D. and Weiss,J.L.
TITLE The neuronal calcium sensor family of Ca2+-binding proteins
JOURNAL Biochem. J. 353 (PT 1), 1-12 (2001)
PUBMED 11115393
REMARK Review article
Erratum:[Biochem J 2001 Mar 15;354(Pt 3):727]
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BQ880305.1, DA092531.1,
AF134479.1, AL161981.1, BM011362.1, BU150740.1, AI564128.1,
AI521726.1, CF453730.1, AI768193.1 and CK301145.1.
Summary: This gene is a member of the neuronal calcium sensor gene
family, which encode calcium-binding proteins expressed
predominantly in neurons. The protein encoded by this gene
regulates G protein-coupled receptor phosphorylation in a
calcium-dependent manner and can substitute for calmodulin. The
protein is associated with secretory granules and modulates
synaptic transmission and synaptic plasticity. Multiple transcript
variants encoding different isoforms have been found for this gene.
[provided by RefSeq, Jul 2008].
Transcript Variant: This variant (2) contains a distinct 5' UTR and
5' coding region, compared to variant 1. The resulting isoform (2)
has a shorter and distinct N-terminus when compared to isoform 1.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BQ880305.1, DA092531.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025084, ERS025090 [ECO:0000348]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-1 BQ880305.1 1-1
2-470 DA092531.1 1-469
471-969 AF134479.1 583-1081
970-1733 AL161981.1 394-1157
1734-3051 AF134479.1 1846-3163
3052-3478 BM011362.1 300-726
3479-3833 BU150740.1 300-654
3834-4120 AI564128.1 62-348 c
4121-4183 AI521726.1 4-66 c
4184-4686 CF453730.1 275-777
4687-4844 AI768193.1 12-169 c
4845-4878 CK301145.1 1-34 c
FEATURES Location/Qualifiers
source 1..4878
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="9q34"
gene 1..4878
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/note="neuronal calcium sensor 1"
/db_xref="GeneID:23413"
/db_xref="HGNC:3953"
/db_xref="MIM:603315"
exon 1..19
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/inference="alignment:Splign:1.39.8"
misc_feature 4..6
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/note="upstream in-frame stop codon"
CDS 10..528
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/note="isoform 2 is encoded by transcript variant 2;
frequenin-like ubiquitous protein; frequenin-like protein;
frequenin homolog"
/codon_start=1
/product="neuronal calcium sensor 1 isoform 2"
/protein_id="NP_001122298.1"
/db_xref="GI:192447423"
/db_xref="CCDS:CCDS48043.1"
/db_xref="GeneID:23413"
/db_xref="HGNC:3953"
/db_xref="MIM:603315"
/translation="
MATITEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV
"
misc_feature 19..492
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/note="Ca2+-binding protein (EF-Hand superfamily) [Signal
transduction mechanisms / Cytoskeleton / Cell division and
chromosome partitioning / General function prediction
only]; Region: FRQ1; COG5126"
/db_xref="CDD:34727"
misc_feature 154..330
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/note="EF-hand, calcium binding motif; A diverse
superfamily of calcium sensors and calcium signal
modulators; most examples in this alignment model have 2
active canonical EF hands. Ca2+ binding induces a
conformational change in the EF-hand motif, leading to...;
Region: EFh; cd00051"
/db_xref="CDD:28933"
misc_feature order(172..174,178..180,184..186,205..207,280..282,
286..288,292..294,313..315)
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/note="Ca2+ binding site [ion binding]; other site"
/db_xref="CDD:28933"
misc_feature 253..471
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/note="EF-hand, calcium binding motif; A diverse
superfamily of calcium sensors and calcium signal
modulators; most examples in this alignment model have 2
active canonical EF hands. Ca2+ binding induces a
conformational change in the EF-hand motif, leading to...;
Region: EFh; cd00051"
/db_xref="CDD:28933"
misc_feature order(280..282,286..288,292..294,313..315,424..426,
430..432,436..438,457..459)
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/note="Ca2+ binding site [ion binding]; other site"
/db_xref="CDD:28933"
exon 20..44
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/inference="alignment:Splign:1.39.8"
exon 45..183
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/inference="alignment:Splign:1.39.8"
variation 57
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:369569947"
variation 90
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:143750486"
variation 126
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:190718593"
variation 129
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:148178859"
variation 141
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="c"
/db_xref="dbSNP:372862177"
variation 166
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:377343889"
exon 184..262
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/inference="alignment:Splign:1.39.8"
variation 186
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:142005773"
variation 191
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:200938140"
variation 205
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:376137684"
variation 219
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:150683155"
variation 225
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:11552457"
variation 260
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:370911031"
exon 263..351
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/inference="alignment:Splign:1.39.8"
variation 300
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:141503212"
variation 311
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:146218396"
exon 352..429
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/inference="alignment:Splign:1.39.8"
variation 409
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="t"
/db_xref="dbSNP:4524901"
exon 430..545
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/inference="alignment:Splign:1.39.8"
variation 435
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:369600917"
variation 457..458
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace=""
/replace="a"
/db_xref="dbSNP:11440892"
variation 460
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:11552456"
variation 471
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="g"
/replace="t"
/db_xref="dbSNP:2277200"
variation 525
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:373209505"
exon 546..4860
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/inference="alignment:Splign:1.39.8"
variation 601
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:370470403"
variation 643
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:11552455"
variation 647
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:189284841"
variation 663
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="g"
/replace="t"
/db_xref="dbSNP:11552458"
variation 684
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:11552454"
variation 720
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="g"
/db_xref="dbSNP:181988596"
variation 750
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:144514863"
variation 758
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:372344853"
variation 829
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:41279184"
variation 890
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:3088039"
variation 891
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace=""
/replace="a"
/db_xref="dbSNP:141172664"
variation 899
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="c"
/db_xref="dbSNP:185182501"
variation 981
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:115131879"
variation 987
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:190972633"
variation 1001
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:182692714"
variation 1021
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:186544417"
variation 1022
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:368867488"
variation 1045
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:1054879"
variation 1059
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:377351642"
variation 1123..1124
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace=""
/replace="t"
/db_xref="dbSNP:200691020"
variation 1126..1127
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace=""
/replace="t"
/db_xref="dbSNP:377232982"
variation 1131..1132
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace=""
/replace="t"
/db_xref="dbSNP:375941933"
variation 1131
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="g"
/replace="t"
/db_xref="dbSNP:191357888"
polyA_site 1139
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
variation 1153
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:370318457"
variation 1167..1168
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace=""
/replace="g"
/db_xref="dbSNP:201900282"
variation 1169..1170
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace=""
/replace="t"
/db_xref="dbSNP:34319101"
variation 1170..1171
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace=""
/replace="t"
/db_xref="dbSNP:11482915"
polyA_site 1209
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
variation 1215
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="g"
/replace="t"
/db_xref="dbSNP:183505584"
variation 1261
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:373759435"
variation 1270
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:118092895"
variation 1288
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:8181096"
variation 1353
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="t"
/db_xref="dbSNP:73670524"
variation 1417
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:192350115"
variation 1462
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:73545592"
variation 1466
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="t"
/db_xref="dbSNP:140307449"
variation 1490
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:373779620"
variation 1527
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:56033557"
variation 1537
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:13296233"
variation 1579
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:36073320"
variation 1596
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:116200382"
variation 1614
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:41280142"
variation 1674
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="g"
/db_xref="dbSNP:7033065"
variation 1700
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:183177403"
variation 1734
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:34954279"
variation 1829
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:374154868"
variation 1841
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:187859521"
variation 1869
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:192706555"
variation 1911
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:116694639"
variation 1924
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="g"
/replace="t"
/db_xref="dbSNP:6478954"
variation 1945
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:7846906"
variation 1964
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="c"
/db_xref="dbSNP:145263859"
variation 1974
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:112487332"
variation 2030
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:184507086"
variation 2039
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:149159807"
variation 2078
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:145020936"
variation 2089
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:189688335"
STS 2114..2227
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/standard_name="2006"
/db_xref="UniSTS:78302"
variation 2152
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:13300858"
variation 2223
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:41316508"
variation 2308
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:369985853"
variation 2314
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:74914651"
variation 2323
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="t"
/db_xref="dbSNP:140742377"
variation 2343
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:192712220"
variation 2363
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="c"
/db_xref="dbSNP:145896702"
variation 2412
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="c"
/db_xref="dbSNP:114418161"
variation 2414
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:117265449"
variation 2536
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:112803517"
variation 2548
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:11552450"
variation 2621
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace=""
/replace="c"
/db_xref="dbSNP:35657891"
variation 2653
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:184428199"
variation 2660
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:79944590"
variation 2676..2677
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace=""
/replace="c"
/db_xref="dbSNP:5900889"
variation 2684
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:10988649"
variation 2746
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:79156389"
variation 2843
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:372893934"
variation 2872
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:371937919"
variation 2903
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:79697564"
variation 2961
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:138455912"
variation 2996
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="c"
/db_xref="dbSNP:189134100"
variation 3001
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:377618746"
variation 3052
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:13710"
variation 3102
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:11552452"
variation 3150
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:115545523"
variation 3198
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="g"
/replace="t"
/db_xref="dbSNP:114502717"
variation 3215
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:12377152"
variation 3339
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="g"
/replace="t"
/db_xref="dbSNP:377713517"
variation 3396
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:181712022"
variation 3417
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:1043368"
variation 3426
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:141952514"
variation 3443
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="g"
/replace="t"
/db_xref="dbSNP:186370226"
variation 3476
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:10988650"
variation 3489
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:190581729"
variation 3496
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:150659490"
variation 3497
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:11552453"
variation 3600
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="g"
/replace="t"
/db_xref="dbSNP:113812485"
variation 3623
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="g"
/db_xref="dbSNP:28678653"
variation 3636
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:709611"
variation 3715..3716
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace=""
/replace="t"
/db_xref="dbSNP:71805474"
variation 3739
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:180862513"
variation 3803
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="g"
/db_xref="dbSNP:112065411"
STS 3831..3985
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/standard_name="RH93523"
/db_xref="UniSTS:85258"
variation 3834
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="g"
/db_xref="dbSNP:11552451"
variation 3878
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="g"
/db_xref="dbSNP:140302160"
variation 3897
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="g"
/db_xref="dbSNP:186003263"
variation 3932
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="g"
/db_xref="dbSNP:76680931"
variation 3957
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="g"
/db_xref="dbSNP:41281144"
variation 3970
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="g"
/db_xref="dbSNP:368270639"
STS 4064..4177
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/standard_name="A001U14"
/db_xref="UniSTS:22548"
variation 4103
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:113006781"
variation 4104..4105
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace=""
/replace="t"
/db_xref="dbSNP:11432743"
variation 4113..4114
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace=""
/replace="t"
/replace="tt"
/db_xref="dbSNP:66906315"
variation 4121..4122
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace=""
/replace="t"
/replace="tt"
/db_xref="dbSNP:66505642"
polyA_signal 4160..4165
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
polyA_site 4183
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
variation 4319
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:201757038"
variation 4358
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="g"
/replace="t"
/db_xref="dbSNP:35224766"
variation 4459
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:7847694"
variation 4460
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:191248234"
variation 4500
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:73545596"
variation 4566
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:73545599"
variation 4567
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:181242413"
variation 4623..4624
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace=""
/replace="caaa"
/db_xref="dbSNP:367634079"
variation 4645
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="g"
/db_xref="dbSNP:185596487"
variation 4676
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="a"
/replace="c"
/db_xref="dbSNP:147435932"
variation 4735
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="g"
/db_xref="dbSNP:1055663"
variation 4825
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:148474902"
polyA_signal 4830..4835
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
variation 4838
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
/replace="c"
/replace="t"
/db_xref="dbSNP:190403603"
polyA_site 4860
/gene="NCS1"
/gene_synonym="FLUP; FREQ"
ORIGIN
gattgagagatggcaacgattaccgagaaggaggtccagcagtggtacaaaggcttcatcaaggactgccccagtgggcagctggatgcggcaggcttccagaagatctacaagcaattcttcccgttcggagaccccaccaagtttgccacatttgttttcaacgtctttgatgaaaacaaggacgggcgaattgagttctccgagttcatccaggcgctgtcggtgacctcacggggaaccctggatgagaagctacggtgggccttcaagctctacgacttggacaatgatggctacatcaccaggaatgagatgctggacattgtggatgccatttaccagatggtggggaataccgtggagctcccagaggaggagaacactcctgagaagagggtggaccggatctttgccatgatggataagaatgccgacgggaagctgaccctgcaggagttccaggagggttccaaggcagacccgtccattgtgcaggcgctgtccctctacgacgggctggtatagtcccaggctggagctggatgcctgggaaccactcacctccttctgtgccatgaggccacctcagccctgacaccaaccccgtgcgtccacccagccttcttccgcatccacacacagccggctgcccttgacccgggaggccccggctctcctctcccctgtcctgcacccatcccccgcctgaagccaccggctccaattgccagcaacctctgcttgtccggaaaacgacaacacgaaatggaaaaggctacagccctctgcataaaccaaggacttggctgcctcgcaggcagcctccgttcctcccgctctcttgcgcgtgtgcttttgttttttattttgaacagacgttttaaaagaaaaaaaaacaactaccttctgtcctagaagacacagactgacagatggggtgaaggcctggggacctcagagaactctgccttgccctcgtccctcgtccttcggcagccggagaggctgtgggtgggccgagggtgtctaggggttctgcctggtcaacgttatttgtcgtcccatcttttggcagcaaaaccacctgcgtggctaggatgattaattatgaggatgatgattttttttgtgataacagtattgtgctttttgtggggaaagtgaggtttttttttatatacatatataattgatatctttaatttattggttgttaactgttgctgctgcctggtgtgtcctcagctcccagggctgcgggcccaccgtttacatgtgcacgccctgacccacctgcccacgccgacttgggaggatggtggcctgcagcggccaagaagccaaaaaaaattttttttttttcagatactgtgcttgatttttggagaggggagaggtggaaattcctaaatggctaatgcactgttccctccagcccgaatgcctcctgccaaaccccttttccctgctgcctctgtccccgcatccttgttctcccctgggtccgtaacattttttccgaggatgaacaggggacatctttaggtttctcaactcttgctttggtgtttgccgcagcatggaaaacagggcgcctaaggctgggagctggaagaaggggcattgggtacccaggcagagtcaggagaggtggtctttgaagtaagttagcagaaatcaaggggacccccgcctccttgggctggggaggggatttcaagatagttcatgactctctcccgctctgccttccctccttcctatctgctttttccagtaaactgcatggtgtccttccctggccttctcttggctcaaaggctgggagggagggaaggagagaagagttccaggcaatcccatcaatatagtccctacacctggggctgcggcccacatgtcttcacggaggcttccagcggtgcctgccactgaggcaggtgcggccccaggaccatcaccaggaatgcgaggccaccctggaccagaggtaggagcccaaggtccggcccttgctctttgattgtgggcagcctcctgccctctctgggtctcagttgccccatctgcagagcgaggaggcccgggctggttggtcttgaaggcccttttccatgccgacatcatgtcactctaggcctggggttcagtttcctgtggctggtgatgctgtggttaagtttgcttgaccccagcagcccgagggactgtctgagtcacagcacagcccctattgcgtggctgctggtgtgtggggtcagttccagcagatgaatgtgtcatgtggcacaccttgtcccttcccgcagcatttcctggttccccccagacccttgagcgctctttgggacccagaaggagtccttgcacagggaaggcttgaggtgagaagccgcttcccagactgtcagggccaggcctgggtctagaattcttgctgctgctttgcagagtcaacagcccatcagcccatgttttagaggggacactttggtcctcggttcccaccctcagcaagcaggcctccagcccgaggaaggcctctgccgtagtgacgttgccgtgtggggctgcgtggctgttccccttggctggagcattcagccaaccccagcgtcccccctgaggcgttcattggcagccccctaggactgcacgctggccccacggtaaccccccctcccccaccaacatcctgcagggatggggtcagtggttccaccttcacaggccactttgaagggtggattctttgaggcccctgccagtcggctccctgctcagctgctggcccgggcgacctgggactcagcaccaacggctgaagtttctcagctgggctctgacctggggtctggggcagggaacgaacatggtggctttgggctgagaggatgagggaggtctttcccaggtcaaattactttcctttggcctctgcctgaggctcgatttgcctctctggtccaatgggactgacactgttgtacaacctgacctgtggctgagggtgtctgggcttaagcatgtggaccccttcggtgtgtccggccttcctccatcgtcctgccctttggccttttggtttgaagccacaggtgtggcttctggccttagcagatggtatgcttgcggaccgcagcccagcatgccggtgggcccacagcccgagccagcccagagctgccggaagggccgcccttcccggccctggcggggtgctggacactggccattttcactagagtttgcctggcagggaccgatctctgccccctcctctccccaggcctctggctgcagtgatgccgcagaatcctgagccaggtgcctcctgagcagcccgtgcgcctctccacagcggcgtttgccacccaatgcggctcgcttcagatgctctgatgcagagggcacgcccatagtccctctgcagagcctcgcactggggccagggcaggcaccagccccaggcggccagtcggccacggcctgtcctcttcctcgtagcgtctgctcctcactttgtgttgatggtgacttaggagaatgttccgattttccatgatctaagcaggccacgtttaaaataacatcaaggcaagcgtacgtgtcaccctctgtactgacatctcttcccctgaaatgcttttcagtttgacagcccgtttcctagacaagtgcacctggggtttcaggaactttgtgttttttcggagggggttggtggggaggtcgggatgcctgggatcccttcctggagaggcaggctgtctctggaaaaagcctccattgcccacccgccaggcggaaagtcaccctgttcccagcgcggtttcagcatttaattttaagggagctaaggaagcgcggcgcgccccctggtggtggtaagccgccaacgcacctgggggctgcaaccccaccggacgggtggtccggagggaggctggagcggggaggcgaggagggggctgtgagtcctcagaggccctgggccaccacatttctggcagcgtttcccagacacccctctgctaggccatccctggatagcaagtgaattaacttaagggcactgtgatgggaagccttgcccccctcttttttttttttttttaatatctgcggaataaacccaatggttaatttttgaatgaataaaaggcttttgttgaataaacagctggtcccatcttctgtcttggcatcttagcatccaggctcaggctctgccccttctccaggatggggtagccccgagtcgccctccccagtctgcacattccctgttgtccctgttcctgcagtggctcccggccccagggaggcccacctcactcccagcctgactcggtggctggcttccttcaggactttgcgcaagtcagttctgctcattgggtctcaatttccccatcccttggatgggagcaagagtctctgctgggcctgcctcgcaggggcctggtgagacccaaatgtgagtgtcatcatcaaagcccctcacagaagtggaggacggtgcccaagagtagcggtttggactgctgctgcctcccacccggagcctgccacttgggggagaaattggtataatgcttgcaaaaacaaacaaacaaaaggcaatgtcttctggttgtggttatttcctttcctgcttgcctccccagccccctttgagtctctttttggggtgccgtcctgtctgaacctgccggtgtgtgtctctggggccagggtcagggcgaggcccaggggtggacaggggccgtgtagcatgccccagcctccccaagctcctgctgtatgtcgtccatgtcacgccaattaaacacgcttcctggacttgtcctcgccaaaaaaaaaaaaaaaaaa
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:23413 -> Molecular function: GO:0005245 [voltage-gated calcium channel activity] evidence: ISS
GeneID:23413 -> Molecular function: GO:0005509 [calcium ion binding] evidence: TAS
GeneID:23413 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:23413 -> Biological process: GO:0010975 [regulation of neuron projection development] evidence: ISS
GeneID:23413 -> Biological process: GO:0045921 [positive regulation of exocytosis] evidence: IEA
GeneID:23413 -> Biological process: GO:0048015 [phosphatidylinositol-mediated signaling] evidence: IEA
GeneID:23413 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:23413 -> Cellular component: GO:0005829 [cytosol] evidence: IEA
GeneID:23413 -> Cellular component: GO:0005886 [plasma membrane] evidence: IDA
GeneID:23413 -> Cellular component: GO:0014069 [postsynaptic density] evidence: IEA
GeneID:23413 -> Cellular component: GO:0030054 [cell junction] evidence: IEA
GeneID:23413 -> Cellular component: GO:0030424 [axon] evidence: IEA
GeneID:23413 -> Cellular component: GO:0030425 [dendrite] evidence: IEA
GeneID:23413 -> Cellular component: GO:0031410 [cytoplasmic vesicle] evidence: IEA
GeneID:23413 -> Cellular component: GO:0032580 [Golgi cisterna membrane] evidence: IEA
GeneID:23413 -> Cellular component: GO:0043231 [intracellular membrane-bounded organelle] evidence: IDA
GeneID:23413 -> Cellular component: GO:0045211 [postsynaptic membrane] evidence: IEA
GeneID:23413 -> Cellular component: GO:0048471 [perinuclear region of cytoplasm] evidence: IEA
by
@meso_cacase at
DBCLS
This page is licensed under a Creative Commons Attribution 2.1 Japan License.