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2024-04-20 06:52:10, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001128206 5554 bp mRNA linear PRI 12-MAY-2013
DEFINITION Homo sapiens sulfatase 1 (SULF1), transcript variant 2, mRNA.
ACCESSION NM_001128206
VERSION NM_001128206.1 GI:189571642
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5554)
AUTHORS Hur,K., Han,T.S., Jung,E.J., Yu,J., Lee,H.J., Kim,W.H., Goel,A. and
Yang,H.K.
TITLE Up-regulated expression of sulfatases (SULF1 and SULF2) as
prognostic and metastasis predictive markers in human gastric
cancer
JOURNAL J. Pathol. 228 (1), 88-98 (2012)
PUBMED 22653794
REMARK GeneRIF: SULF1 may serve as a promising biomarker for patients with
gastric carcinoma.
REFERENCE 2 (bases 1 to 5554)
AUTHORS Manning,A.K., Hivert,M.F., Scott,R.A., Grimsby,J.L.,
Bouatia-Naji,N., Chen,H., Rybin,D., Liu,C.T., Bielak,L.F.,
Prokopenko,I., Amin,N., Barnes,D., Cadby,G., Hottenga,J.J.,
Ingelsson,E., Jackson,A.U., Johnson,T., Kanoni,S., Ladenvall,C.,
Lagou,V., Lahti,J., Lecoeur,C., Liu,Y., Martinez-Larrad,M.T.,
Montasser,M.E., Navarro,P., Perry,J.R., Rasmussen-Torvik,L.J.,
Salo,P., Sattar,N., Shungin,D., Strawbridge,R.J., Tanaka,T., van
Duijn,C.M., An,P., de Andrade,M., Andrews,J.S., Aspelund,T.,
Atalay,M., Aulchenko,Y., Balkau,B., Bandinelli,S., Beckmann,J.S.,
Beilby,J.P., Bellis,C., Bergman,R.N., Blangero,J., Boban,M.,
Boehnke,M., Boerwinkle,E., Bonnycastle,L.L., Boomsma,D.I.,
Borecki,I.B., Bottcher,Y., Bouchard,C., Brunner,E., Budimir,D.,
Campbell,H., Carlson,O., Chines,P.S., Clarke,R., Collins,F.S.,
Corbaton-Anchuelo,A., Couper,D., de Faire,U., Dedoussis,G.V.,
Deloukas,P., Dimitriou,M., Egan,J.M., Eiriksdottir,G., Erdos,M.R.,
Eriksson,J.G., Eury,E., Ferrucci,L., Ford,I., Forouhi,N.G.,
Fox,C.S., Franzosi,M.G., Franks,P.W., Frayling,T.M., Froguel,P.,
Galan,P., de Geus,E., Gigante,B., Glazer,N.L., Goel,A., Groop,L.,
Gudnason,V., Hallmans,G., Hamsten,A., Hansson,O., Harris,T.B.,
Hayward,C., Heath,S., Hercberg,S., Hicks,A.A., Hingorani,A.,
Hofman,A., Hui,J., Hung,J., Jarvelin,M.R., Jhun,M.A., Johnson,P.C.,
Jukema,J.W., Jula,A., Kao,W.H., Kaprio,J., Kardia,S.L.,
Keinanen-Kiukaanniemi,S., Kivimaki,M., Kolcic,I., Kovacs,P.,
Kumari,M., Kuusisto,J., Kyvik,K.O., Laakso,M., Lakka,T.,
Lannfelt,L., Lathrop,G.M., Launer,L.J., Leander,K., Li,G., Lind,L.,
Lindstrom,J., Lobbens,S., Loos,R.J., Luan,J., Lyssenko,V., Magi,R.,
Magnusson,P.K., Marmot,M., Meneton,P., Mohlke,K.L., Mooser,V.,
Morken,M.A., Miljkovic,I., Narisu,N., O'Connell,J., Ong,K.K.,
Oostra,B.A., Palmer,L.J., Palotie,A., Pankow,J.S., Peden,J.F.,
Pedersen,N.L., Pehlic,M., Peltonen,L., Penninx,B., Pericic,M.,
Perola,M., Perusse,L., Peyser,P.A., Polasek,O., Pramstaller,P.P.,
Province,M.A., Raikkonen,K., Rauramaa,R., Rehnberg,E., Rice,K.,
Rotter,J.I., Rudan,I., Ruokonen,A., Saaristo,T., Sabater-Lleal,M.,
Salomaa,V., Savage,D.B., Saxena,R., Schwarz,P., Seedorf,U.,
Sennblad,B., Serrano-Rios,M., Shuldiner,A.R., Sijbrands,E.J.,
Siscovick,D.S., Smit,J.H., Small,K.S., Smith,N.L., Smith,A.V.,
Stancakova,A., Stirrups,K., Stumvoll,M., Sun,Y.V., Swift,A.J.,
Tonjes,A., Tuomilehto,J., Trompet,S., Uitterlinden,A.G.,
Uusitupa,M., Vikstrom,M., Vitart,V., Vohl,M.C., Voight,B.F.,
Vollenweider,P., Waeber,G., Waterworth,D.M., Watkins,H.,
Wheeler,E., Widen,E., Wild,S.H., Willems,S.M., Willemsen,G.,
Wilson,J.F., Witteman,J.C., Wright,A.F., Yaghootkar,H.,
Zelenika,D., Zemunik,T., Zgaga,L., Wareham,N.J., McCarthy,M.I.,
Barroso,I., Watanabe,R.M., Florez,J.C., Dupuis,J., Meigs,J.B. and
Langenberg,C.
CONSRTM DIAbetes Genetics Replication And Meta-analysis (DIAGRAM)
Consortium; Multiple Tissue Human Expression Resource (MUTHER)
Consortium
TITLE A genome-wide approach accounting for body mass index identifies
genetic variants influencing fasting glycemic traits and insulin
resistance
JOURNAL Nat. Genet. 44 (6), 659-669 (2012)
PUBMED 22581228
REMARK Publication Status: Online-Only
REFERENCE 3 (bases 1 to 5554)
AUTHORS Zhang,H., Newman,D.R. and Sannes,P.L.
TITLE HSULF-1 inhibits ERK and AKT signaling and decreases cell viability
in vitro in human lung epithelial cells
JOURNAL Respir. Res. 13, 69 (2012)
PUBMED 22873647
REMARK GeneRIF: HSULF-1 is expressed at lower levels in H292 lung cancer
cells than in normal human alveolar cells and that its
over-expression reduced cell viability in H292 cells by inducing
apoptotic pathways, at least in part by inhibiting ERK/Akt
signaling
Publication Status: Online-Only
REFERENCE 4 (bases 1 to 5554)
AUTHORS Gopal,G., Shirley,S., Raja,U.M. and Rajkumar,T.
TITLE Endo-sulfatase Sulf-1 protein expression is down-regulated in
gastric cancer
JOURNAL Asian Pac. J. Cancer Prev. 13 (2), 641-646 (2012)
PUBMED 22524839
REMARK GeneRIF: Sulf-1 protein expression is down-regulated in gastric
cancer.
REFERENCE 5 (bases 1 to 5554)
AUTHORS N'Diaye,A., Chen,G.K., Palmer,C.D., Ge,B., Tayo,B., Mathias,R.A.,
Ding,J., Nalls,M.A., Adeyemo,A., Adoue,V., Ambrosone,C.B.,
Atwood,L., Bandera,E.V., Becker,L.C., Berndt,S.I., Bernstein,L.,
Blot,W.J., Boerwinkle,E., Britton,A., Casey,G., Chanock,S.J.,
Demerath,E., Deming,S.L., Diver,W.R., Fox,C., Harris,T.B.,
Hernandez,D.G., Hu,J.J., Ingles,S.A., John,E.M., Johnson,C.,
Keating,B., Kittles,R.A., Kolonel,L.N., Kritchevsky,S.B., Le
Marchand,L., Lohman,K., Liu,J., Millikan,R.C., Murphy,A.,
Musani,S., Neslund-Dudas,C., North,K.E., Nyante,S., Ogunniyi,A.,
Ostrander,E.A., Papanicolaou,G., Patel,S., Pettaway,C.A.,
Press,M.F., Redline,S., Rodriguez-Gil,J.L., Rotimi,C.,
Rybicki,B.A., Salako,B., Schreiner,P.J., Signorello,L.B.,
Singleton,A.B., Stanford,J.L., Stram,A.H., Stram,D.O., Strom,S.S.,
Suktitipat,B., Thun,M.J., Witte,J.S., Yanek,L.R., Ziegler,R.G.,
Zheng,W., Zhu,X., Zmuda,J.M., Zonderman,A.B., Evans,M.K., Liu,Y.,
Becker,D.M., Cooper,R.S., Pastinen,T., Henderson,B.E.,
Hirschhorn,J.N., Lettre,G. and Haiman,C.A.
TITLE Identification, replication, and fine-mapping of Loci associated
with adult height in individuals of african ancestry
JOURNAL PLoS Genet. 7 (10), E1002298 (2011)
PUBMED 21998595
REMARK Erratum:[PLoS Genet. 2011 Nov;7(11).
doi:10.1371/annotation/58c67154-3f10-4155-9085-dcd6e3689008]
REFERENCE 6 (bases 1 to 5554)
AUTHORS Dai,Y., Yang,Y., MacLeod,V., Yue,X., Rapraeger,A.C., Shriver,Z.,
Venkataraman,G., Sasisekharan,R. and Sanderson,R.D.
TITLE HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth
in vivo
JOURNAL J. Biol. Chem. 280 (48), 40066-40073 (2005)
PUBMED 16192265
REMARK GeneRIF: HSulf-1 and HSulf-2 have roles in inhibiting myeloma tumor
growth
GeneRIF: HSulf-1 (SULF1) and HSulf-2 (SULF2) are potent inhibitors
of myeloma tumor growth in vivo.
REFERENCE 7 (bases 1 to 5554)
AUTHORS Li,J., Kleeff,J., Abiatari,I., Kayed,H., Giese,N.A., Felix,K.,
Giese,T., Buchler,M.W. and Friess,H.
TITLE Enhanced levels of Hsulf-1 interfere with heparin-binding growth
factor signaling in pancreatic cancer
JOURNAL Mol. Cancer 4 (1), 14 (2005)
PUBMED 15817123
REMARK GeneRIF: High expression of Hsulf-1 occurs in the stromal elements
as well as in the tumor cells in pancreatic cancer and interferes
with heparin-binding growth factor signaling
Publication Status: Online-Only
REFERENCE 8 (bases 1 to 5554)
AUTHORS Lai,J.P., Chien,J.R., Moser,D.R., Staub,J.K., Aderca,I.,
Montoya,D.P., Matthews,T.A., Nagorney,D.M., Cunningham,J.M.,
Smith,D.I., Greene,E.L., Shridhar,V. and Roberts,L.R.
TITLE hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells
by decreasing heparin-binding growth factor signaling
JOURNAL Gastroenterology 126 (1), 231-248 (2004)
PUBMED 14699503
REMARK GeneRIF: Down-regulation of hSulf1 contributes to
hepatocarcinogenesis by enhancing heparin-binding growth factor
signaling and resistance to apoptosis.
REFERENCE 9 (bases 1 to 5554)
AUTHORS Lai,J., Chien,J., Staub,J., Avula,R., Greene,E.L., Matthews,T.A.,
Smith,D.I., Kaufmann,S.H., Roberts,L.R. and Shridhar,V.
TITLE Loss of HSulf-1 up-regulates heparin-binding growth factor
signaling in cancer
JOURNAL J. Biol. Chem. 278 (25), 23107-23117 (2003)
PUBMED 12686563
REMARK GeneRIF: modulates signaling by heparin-binding growth factors, and
HSulf-1 down-regulation represents a novel mechanism by which
cancer cells can enhance growth factor signaling
REFERENCE 10 (bases 1 to 5554)
AUTHORS Morimoto-Tomita,M., Uchimura,K., Werb,Z., Hemmerich,S. and
Rosen,S.D.
TITLE Cloning and characterization of two extracellular heparin-degrading
endosulfatases in mice and humans
JOURNAL J. Biol. Chem. 277 (51), 49175-49185 (2002)
PUBMED 12368295
REMARK GeneRIF: Sulfs are extracellular endosulfatases with strong
potential for modulating the interactions of heparan sulfate
proteoglycans in the extracellular microenvironment
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
DA726387.1, AY101175.1 and AF545571.1.
Summary: Heparan sulfate proteoglycans (HSPGs) act as coreceptors
for numerous heparin-binding growth factors and cytokines and are
involved in cell signaling. Heparan sulfate 6-O-endosulfatases,
such as SULF1, selectively remove 6-O-sulfate groups from heparan
sulfate. This activity modulates the effects of heparan sulfate by
altering binding sites for signaling molecules (Dai et al., 2005
[PubMed 16192265]).[supplied by OMIM, Mar 2008].
Transcript Variant: This variant (2) differs in the 5' UTR compared
to variant 1. Variants 1-4 encode the same protein.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AY101175.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025081, ERS025083 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-53 DA726387.1 1-53
54-3719 AY101175.1 1-3666
3720-5554 AF545571.1 3865-5699
FEATURES Location/Qualifiers
source 1..5554
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8q13.1"
gene 1..5554
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="sulfatase 1"
/db_xref="GeneID:23213"
/db_xref="HGNC:20391"
/db_xref="MIM:610012"
exon 1..333
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 46
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:191002941"
variation 57
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:183523196"
variation 121
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:2725092"
variation 188
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376975556"
variation 224
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139415692"
variation 301
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:112601068"
variation 302
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:79820523"
variation 311..313
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace=""
/replace="aga"
/db_xref="dbSNP:371632962"
variation 324
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:7840249"
exon 334..428
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 342
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:185882678"
variation 385
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:13264163"
variation 406
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148950847"
exon 429..501
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
misc_feature 493..495
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="upstream in-frame stop codon"
exon 502..733
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 517
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376187821"
variation 552
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:369974279"
CDS 562..3177
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="sulfatase FP; extracellular sulfatase Sulf-1"
/codon_start=1
/product="extracellular sulfatase Sulf-1 precursor"
/protein_id="NP_001121678.1"
/db_xref="GI:189571643"
/db_xref="CCDS:CCDS6204.1"
/db_xref="GeneID:23213"
/db_xref="HGNC:20391"
/db_xref="MIM:610012"
/translation="
MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLLTVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHTRQTRSLSVEFEGEIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLADSSNAVGPPTTVRVTHKCFILPNDSIHCERELYQSARAWKDHKAYIDKEIEALQDKIKNLREVRGHLKRRKPEECSCSKQSYYNKEKGVKKQEKLKSHLHPFKEAAQEVDSKLQLFKENNRRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWCLRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGYKQCNPRPKNLDVGNKDGGSYDLHRGQLWDGWEG
"
sig_peptide 562..627
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="COORDINATES: ab initio prediction:SignalP:4.0"
mat_peptide 628..3174
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/product="Extracellular sulfatase Sulf-1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q8IWU6.1)"
misc_feature 685..>1743
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="Arylsulfatase A and related enzymes [Inorganic ion
transport and metabolism]; Region: AslA; COG3119"
/db_xref="CDD:32933"
misc_feature 688..1740
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="Sulfatase; Region: Sulfatase; pfam00884"
/db_xref="CDD:201490"
misc_feature 2158..2601
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="Sulfatase protein; Region: DUF3740; pfam12548"
/db_xref="CDD:204957"
variation 623
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:201640007"
variation 630
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201650068"
variation 644
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:376825615"
variation 659
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:145127325"
variation 675
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:367922640"
variation 676
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:142027500"
variation 714
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:138943816"
exon 734..973
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 742
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:199820581"
variation 778
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:201774043"
variation 780
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:141505559"
variation 812
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:113938874"
variation 828
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:6984529"
variation 833
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149786573"
variation 843
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:377416230"
variation 849
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:138186217"
variation 868
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:200955613"
variation 869
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370346553"
variation 888
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370128603"
variation 909
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370291955"
variation 932
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:147909650"
exon 974..1125
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 975
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:149562933"
variation 1002
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:371221472"
variation 1021
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:147245253"
variation 1050
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:199957740"
variation 1083
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139810682"
variation 1084
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200127043"
variation 1085
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:186655894"
exon 1126..1295
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1200
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:191906713"
variation 1203
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:374058291"
variation 1230
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:111474126"
variation 1233
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:368146472"
variation 1236
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:77728226"
variation 1272
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372034572"
exon 1296..1446
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1341
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377164865"
variation 1351
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:112367866"
variation 1393
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:202004083"
variation 1410
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:141571826"
variation 1419
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61746702"
exon 1447..1622
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1449
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:142148202"
variation 1506
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201468946"
variation 1530
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:377634023"
variation 1577
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61747207"
exon 1623..1751
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1627
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199804686"
variation 1628
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:374371569"
variation 1636
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:140542311"
variation 1656
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:144010163"
variation 1657
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:201478955"
variation 1662
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:146417849"
variation 1672
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:118056333"
variation 1690
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:201919147"
variation 1693
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:371818580"
variation 1706
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:201782679"
exon 1752..1808
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
exon 1809..1938
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1820
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201100928"
variation 1891
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:145174051"
variation 1932
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:112123068"
variation 1934
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148982651"
exon 1939..2155
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1939
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:199539739"
variation 1953
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:147479634"
variation 1968
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:374949302"
variation 2010
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:367667000"
variation 2020
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372786570"
variation 2028
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148125441"
variation 2030
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:141888575"
variation 2035
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201173589"
variation 2040
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:146435519"
variation 2041
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368427346"
variation 2042
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:112120588"
variation 2044
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:142971465"
variation 2045
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372337091"
variation 2055
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:375512132"
variation 2075
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:369545860"
variation 2088
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200268962"
variation 2090
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372839295"
variation 2096
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:202168144"
variation 2100
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:147223148"
variation 2119
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:374818506"
variation 2124
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368822296"
variation 2150
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139600896"
exon 2156..2411
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2156
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149298828"
variation 2183
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370846825"
variation 2206
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201229545"
variation 2282
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199742300"
variation 2306
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:138876060"
variation 2343
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:370806055"
variation 2348
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144546726"
variation 2350
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61747130"
variation 2369
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:61740823"
variation 2373
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:375090509"
variation 2374
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144030540"
variation 2377
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:146445328"
variation 2381
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:367704931"
variation 2395
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:200550270"
variation 2398
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:370193108"
exon 2412..2508
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2475
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:140509610"
variation 2503
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376608568"
exon 2509..2603
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
exon 2604..2669
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2613
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370172405"
exon 2670..2845
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2703
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:143120352"
variation 2716..2718
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace=""
/replace="aac"
/db_xref="dbSNP:150178205"
variation 2722
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377353091"
variation 2723
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369423636"
variation 2726
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:373878204"
variation 2730
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:143386315"
variation 2732
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:199811211"
variation 2756
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:199542001"
variation 2845
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370600729"
exon 2846..2988
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2868
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:190311964"
variation 2915
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:150467604"
variation 2948
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:145335171"
variation 2955
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:78063897"
variation 2965
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:74480225"
exon 2989..3112
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 3001
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:117639561"
variation 3008
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:111626231"
variation 3038
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:148555931"
variation 3045
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:146601124"
variation 3054
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368328719"
variation 3092
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:139106228"
variation 3095
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372242544"
variation 3110
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:143009161"
exon 3113..3146
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 3137
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:143631855"
exon 3147..5554
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 3148
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148285446"
variation 3157
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201165394"
variation 3179
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:141331130"
variation 3331
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369995251"
variation 3358..3361
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace=""
/replace="aaat"
/db_xref="dbSNP:112665345"
variation 3414
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:371124844"
variation 3418
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:112715006"
variation 3442
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:77871693"
variation 3467
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:191954863"
variation 3487
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:111938908"
variation 3506
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:148648757"
variation 3566
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:115563984"
variation 3604
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:183717149"
variation 3613
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:75724852"
variation 3625
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:114581461"
variation 3676
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:72660109"
variation 3686
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:187437769"
variation 3720
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:3802278"
variation 3788
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:59068490"
variation 3870
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139690250"
variation 3874
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:371075932"
variation 3898
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:145279779"
variation 3938
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:6990375"
variation 3982
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:189672278"
variation 4029
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:11996377"
variation 4044
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:1130242"
variation 4119
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372074006"
variation 4143
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:59364549"
variation 4166
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:182489932"
variation 4172
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:76316652"
variation 4280
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:147649872"
variation 4291
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:187129161"
variation 4363
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:374978465"
variation 4379
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:191896243"
variation 4388
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:367559651"
variation 4410
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:183580848"
variation 4475
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:140433867"
STS 4534..4655
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/standard_name="RH47887"
/db_xref="UniSTS:48570"
variation 4541
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:188265806"
variation 4628
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:193164086"
variation 4654
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149994968"
variation 4664
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:185376784"
variation 4880
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:189504583"
variation 5081
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:191238908"
STS 5339..5521
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/standard_name="RH98994"
/db_xref="UniSTS:89243"
variation 5342
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372371432"
variation 5411
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:3087714"
ORIGIN
gtgatgataataatacgcgggcttatataaccgtcttcatcttgcgagcacttcgcagaccgtcgctaatgaatcttggggccggtgtcgggccggggcggcttgatcggcaactaggaaaccccaggcgcagaggccaggagcgagggcagcgaggatcagaggccaggccttcccggctgccggcgctcctcggaggtcagggcagatgaggaacatgactctcccccttcggaggaggaaggaagtcccgctgccaccttatctctgctcctctgcctcctccctgttcccagagctttttctctagagaagattttgaaggcggcttttgtgctgacggccacccaccatcatctaaagaagataaacttggcaaatgacatgcaggttcttcaaggcagaataattgcagaaaatcttcaaaggaccctatctgcagatgttctgaatacctctgagaatagagattgattattcaaccaggatacctaattcaagaactccagaaatcaggagacggagacattttgtcagttttgcaacattggaccaaatacaatgaagtattcttgctgtgctctggttttggctgtcctgggcacagaattgctgggaagcctctgttcgactgtcagatccccgaggttcagaggacggatacagcaggaacgaaaaaacatccgacccaacattattcttgtgcttaccgatgatcaagatgtggagctggggtccctgcaagtcatgaacaaaacgagaaagattatggaacatgggggggccaccttcatcaatgcctttgtgactacacccatgtgctgcccgtcacggtcctccatgctcaccgggaagtatgtgcacaatcacaatgtctacaccaacaacgagaactgctcttccccctcgtggcaggccatgcatgagcctcggacttttgctgtatatcttaacaacactggctacagaacagccttttttggaaaatacctcaatgaatataatggcagctacatcccccctgggtggcgagaatggcttggattaatcaagaattctcgcttctataattacactgtttgtcgcaatggcatcaaagaaaagcatggatttgattatgcaaaggactacttcacagacttaatcactaacgagagcattaattacttcaaaatgtctaagagaatgtatccccataggcccgttatgatggtgatcagccacgctgcgccccacggccccgaggactcagccccacagttttctaaactgtaccccaatgcttcccaacacataactcctagttataactatgcaccaaatatggataaacactggattatgcagtacacaggaccaatgctgcccatccacatggaatttacaaacattctacagcgcaaaaggctccagactttgatgtcagtggatgattctgtggagaggctgtataacatgctcgtggagacgggggagctggagaatacttacatcatttacaccgccgaccatggttaccatattgggcagtttggactggtcaaggggaaatccatgccatatgactttgatattcgtgtgcctttttttattcgtggtccaagtgtagaaccaggatcaatagtcccacagatcgttctcaacattgacttggcccccacgatcctggatattgctgggctcgacacacctcctgatgtggacggcaagtctgtcctcaaacttctggacccagaaaagccaggtaacaggtttcgaacaaacaagaaggccaaaatttggcgtgatacattcctagtggaaagaggcaaatttctacgtaagaaggaagaatccagcaagaatatccaacagtcaaatcacttgcccaaatatgaacgggtcaaagaactatgccagcaggccaggtaccagacagcctgtgaacaaccggggcagaagtggcaatgcattgaggatacatctggcaagcttcgaattcacaagtgtaaaggacccagtgacctgctcacagtccggcagagcacgcggaacctctacgctcgcggcttccatgacaaagacaaagagtgcagttgtagggagtctggttaccgtgccagcagaagccaaagaaagagtcaacggcaattcttgagaaaccaggggactccaaagtacaagcccagatttgtccatactcggcagacacgttccttgtccgtcgaatttgaaggtgaaatatatgacataaatctggaagaagaagaagaattgcaagtgttgcaaccaagaaacattgctaagcgtcatgatgaaggccacaaggggccaagagatctccaggcttccagtggtggcaacaggggcaggatgctggcagatagcagcaacgccgtgggcccacctaccactgtccgagtgacacacaagtgttttattcttcccaatgactctatccattgtgagagagaactgtaccaatcggccagagcgtggaaggaccataaggcatacattgacaaagagattgaagctctgcaagataaaattaagaatttaagagaagtgagaggacatctgaagagaaggaagcctgaggaatgtagctgcagtaaacaaagctattacaataaagagaaaggtgtaaaaaagcaagagaaattaaagagccatcttcacccattcaaggaggctgctcaggaagtagatagcaaactgcaacttttcaaggagaacaaccgtaggaggaagaaggagaggaaggagaagagacggcagaggaagggggaagagtgcagcctgcctggcctcacttgcttcacgcatgacaacaaccactggcagacagccccgttctggaacctgggatctttctgtgcttgcacgagttctaacaataacacctactggtgtttgcgtacagttaatgagacgcataattttcttttctgtgagtttgctactggctttttggagtattttgatatgaatacagatccttatcagctcacaaatacagtgcacacggtagaacgaggcattttgaatcagctacacgtacaactaatggagctcagaagctgtcaaggatataagcagtgcaacccaagacctaagaatcttgatgttggaaataaagatggaggaagctatgacctacacagaggacagttatgggatggatgggaaggttaatcagccccgtctcactgcagacatcaactggcaaggcctagaggagctacacagtgtgaatgaaaacatctatgagtacagacaaaactacagacttagtctggtggactggactaattacttgaaggatttagatagagtatttgcactgctgaagagtcactatgagcaaaataaaacaaataagactcaaactgctcaaagtgacgggttcttggttgtctctgctgagcacgctgtgtcaatggagatggcctctgctgactcagatgaagacccaaggcataaggttgggaaaacacctcatttgaccttgccagctgaccttcaaaccctgcatttgaaccgaccaacattaagtccagagagtaaacttgaatggaataacgacattccagaagttaatcatttgaattctgaacactggagaaaaaccgaaaaatggacggggcatgaagagactaatcatctggaaaccgatttcagtggcgatggcatgacagagctagagctcgggcccagccccaggctgcagcccattcgcaggcacccgaaagaacttccccagtatggtggtcctggaaaggacatttttgaagatcaactatatcttcctgtgcattccgatggaatttcagttcatcagatgttcaccatggccaccgcagaacaccgaagtaattccagcatagcggggaagatgttgaccaaggtggagaagaatcacgaaaaggagaagtcacagcacctagaaggcagcgcctcctcttcactctcctctgattagatgaaactgttaccttaccctaaacacagtatttctttttaacttttttatttgtaaactaataaaggtaatcacagccaccaacattccaagctaccctgggtacctttgtgcagtagaagctagtgagcatgtgagcaagcggtgtgcacacggagactcatcgttataatttactatctgccaagagtagaaagaaaggctggggatatttgggttggcttggttttgattttttgcttgtttgtttgttttgtactaaaacagtattatcttttgaatatcgtagggacataagtatatacatgttatccaatcaagatggctagaatggtgcctttctgagtgtctaaaacttgacacccctggtaaatctttcaacacacttccactgcctgcgtaatgaagttttgattcatttttaaccactggaatttttcaatgccgtcattttcagttagatgattttgcactttgagattaaaatgccatgtctatttgattagtcttatttttttatttttacaggcttatcagtctcactgttggctgtcattgtgacaaagtcaaataaacccccaaggacgacacacagtatggatcacatattgtttgacattaagcttttgccagaaaatgttgcatgtgttttacctcgacttgctaaaatcgattagcagaaaggcatggctaataatgttggtggtgaaaataaataaataagtaaacaaaatgaagattgcctgctctctctgtgcctagcctcaaagcgttcatcatacatcatacctttaagattgctatattttgggttattttcttgacaggagaaaaagatctaaagatcttttattttcatcttttttggttttcttggcatgactaagaagcttaaatgttgataaaatatgactagttttgaatttacaccaagaacttctcaataaaagaaaatcatgaatgctccacaatttcaacataccacaagagaagttaatttcttaacattgtgttctatgattatttgtaagaccttcaccaagttctgatatcttttaaagacatagttcaaaattgcttttgaaaatctgtattcttgaaaatatccttgttgtgtattaggtttttaaataccagctaaaggattacctcactgagtcatcagtaccctcctattcagctccccaagatgatgtgtttttgcttaccctaagagaggttttcttcttatttttagataattcaagtgcttagataaattatgttttctttaagtgtttatggtaaactcttttaaagaaaatttaatatgttatagctgaatctttttggtaactttaaatctttatcatagactctgtacatatgttcaaattagctgcttgcctgatgtgtgtatcatcggtgggatgacagaacaaacatatttatgatcatgaataatgtgctttgtaaaaagatttcaagttattaggaagcatactctgttttttaatcatgtataatattccatgatacttttatagaacaattctggcttcaggaaagtctagaagcaatatttcttcaaataaaaggtgtttaaacttt
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:23213 -> Molecular function: GO:0004065 [arylsulfatase activity] evidence: IDA
GeneID:23213 -> Molecular function: GO:0004065 [arylsulfatase activity] evidence: IMP
GeneID:23213 -> Molecular function: GO:0005509 [calcium ion binding] evidence: IEA
GeneID:23213 -> Molecular function: GO:0008449 [N-acetylglucosamine-6-sulfatase activity] evidence: IDA
GeneID:23213 -> Molecular function: GO:0008449 [N-acetylglucosamine-6-sulfatase activity] evidence: IMP
GeneID:23213 -> Biological process: GO:0001822 [kidney development] evidence: ISS
GeneID:23213 -> Biological process: GO:0001937 [negative regulation of endothelial cell proliferation] evidence: IDA
GeneID:23213 -> Biological process: GO:0002063 [chondrocyte development] evidence: ISS
GeneID:23213 -> Biological process: GO:0003094 [glomerular filtration] evidence: ISS
GeneID:23213 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:23213 -> Biological process: GO:0010575 [positive regulation vascular endothelial growth factor production] evidence: ISS
GeneID:23213 -> Biological process: GO:0014846 [esophagus smooth muscle contraction] evidence: ISS
GeneID:23213 -> Biological process: GO:0016525 [negative regulation of angiogenesis] evidence: IDA
GeneID:23213 -> Biological process: GO:0030177 [positive regulation of Wnt receptor signaling pathway] evidence: IDA
GeneID:23213 -> Biological process: GO:0030201 [heparan sulfate proteoglycan metabolic process] evidence: IDA
GeneID:23213 -> Biological process: GO:0030201 [heparan sulfate proteoglycan metabolic process] evidence: NAS
GeneID:23213 -> Biological process: GO:0030336 [negative regulation of cell migration] evidence: IMP
GeneID:23213 -> Biological process: GO:0030513 [positive regulation of BMP signaling pathway] evidence: IMP
GeneID:23213 -> Biological process: GO:0032836 [glomerular basement membrane development] evidence: ISS
GeneID:23213 -> Biological process: GO:0035860 [glial cell-derived neurotrophic factor receptor signaling pathway] evidence: ISS
GeneID:23213 -> Biological process: GO:0040036 [regulation of fibroblast growth factor receptor signaling pathway] evidence: IMP
GeneID:23213 -> Biological process: GO:0040037 [negative regulation of fibroblast growth factor receptor signaling pathway] evidence: IMP
GeneID:23213 -> Biological process: GO:0040037 [negative regulation of fibroblast growth factor receptor signaling pathway] evidence: ISS
GeneID:23213 -> Biological process: GO:0048010 [vascular endothelial growth factor receptor signaling pathway] evidence: IDA
GeneID:23213 -> Biological process: GO:0048706 [embryonic skeletal system development] evidence: ISS
GeneID:23213 -> Biological process: GO:0051216 [cartilage development] evidence: ISS
GeneID:23213 -> Biological process: GO:0060348 [bone development] evidence: ISS
GeneID:23213 -> Biological process: GO:0060384 [innervation] evidence: ISS
GeneID:23213 -> Biological process: GO:0060686 [negative regulation of prostatic bud formation] evidence: ISS
GeneID:23213 -> Cellular component: GO:0005615 [extracellular space] evidence: IDA
GeneID:23213 -> Cellular component: GO:0005615 [extracellular space] evidence: NAS
GeneID:23213 -> Cellular component: GO:0005783 [endoplasmic reticulum] evidence: IDA
GeneID:23213 -> Cellular component: GO:0005794 [Golgi apparatus] evidence: ISS
GeneID:23213 -> Cellular component: GO:0005795 [Golgi stack] evidence: IEA
GeneID:23213 -> Cellular component: GO:0005886 [plasma membrane] evidence: ISS
GeneID:23213 -> Cellular component: GO:0009986 [cell surface] evidence: IDA
GeneID:23213 -> Cellular component: GO:0045121 [membrane raft] evidence: IDA
by
@meso_cacase at
DBCLS
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