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2024-04-19 17:34:45, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001128205 5716 bp mRNA linear PRI 12-MAY-2013
DEFINITION Homo sapiens sulfatase 1 (SULF1), transcript variant 1, mRNA.
ACCESSION NM_001128205
VERSION NM_001128205.1 GI:189571640
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5716)
AUTHORS Hur,K., Han,T.S., Jung,E.J., Yu,J., Lee,H.J., Kim,W.H., Goel,A. and
Yang,H.K.
TITLE Up-regulated expression of sulfatases (SULF1 and SULF2) as
prognostic and metastasis predictive markers in human gastric
cancer
JOURNAL J. Pathol. 228 (1), 88-98 (2012)
PUBMED 22653794
REMARK GeneRIF: SULF1 may serve as a promising biomarker for patients with
gastric carcinoma.
REFERENCE 2 (bases 1 to 5716)
AUTHORS Manning,A.K., Hivert,M.F., Scott,R.A., Grimsby,J.L.,
Bouatia-Naji,N., Chen,H., Rybin,D., Liu,C.T., Bielak,L.F.,
Prokopenko,I., Amin,N., Barnes,D., Cadby,G., Hottenga,J.J.,
Ingelsson,E., Jackson,A.U., Johnson,T., Kanoni,S., Ladenvall,C.,
Lagou,V., Lahti,J., Lecoeur,C., Liu,Y., Martinez-Larrad,M.T.,
Montasser,M.E., Navarro,P., Perry,J.R., Rasmussen-Torvik,L.J.,
Salo,P., Sattar,N., Shungin,D., Strawbridge,R.J., Tanaka,T., van
Duijn,C.M., An,P., de Andrade,M., Andrews,J.S., Aspelund,T.,
Atalay,M., Aulchenko,Y., Balkau,B., Bandinelli,S., Beckmann,J.S.,
Beilby,J.P., Bellis,C., Bergman,R.N., Blangero,J., Boban,M.,
Boehnke,M., Boerwinkle,E., Bonnycastle,L.L., Boomsma,D.I.,
Borecki,I.B., Bottcher,Y., Bouchard,C., Brunner,E., Budimir,D.,
Campbell,H., Carlson,O., Chines,P.S., Clarke,R., Collins,F.S.,
Corbaton-Anchuelo,A., Couper,D., de Faire,U., Dedoussis,G.V.,
Deloukas,P., Dimitriou,M., Egan,J.M., Eiriksdottir,G., Erdos,M.R.,
Eriksson,J.G., Eury,E., Ferrucci,L., Ford,I., Forouhi,N.G.,
Fox,C.S., Franzosi,M.G., Franks,P.W., Frayling,T.M., Froguel,P.,
Galan,P., de Geus,E., Gigante,B., Glazer,N.L., Goel,A., Groop,L.,
Gudnason,V., Hallmans,G., Hamsten,A., Hansson,O., Harris,T.B.,
Hayward,C., Heath,S., Hercberg,S., Hicks,A.A., Hingorani,A.,
Hofman,A., Hui,J., Hung,J., Jarvelin,M.R., Jhun,M.A., Johnson,P.C.,
Jukema,J.W., Jula,A., Kao,W.H., Kaprio,J., Kardia,S.L.,
Keinanen-Kiukaanniemi,S., Kivimaki,M., Kolcic,I., Kovacs,P.,
Kumari,M., Kuusisto,J., Kyvik,K.O., Laakso,M., Lakka,T.,
Lannfelt,L., Lathrop,G.M., Launer,L.J., Leander,K., Li,G., Lind,L.,
Lindstrom,J., Lobbens,S., Loos,R.J., Luan,J., Lyssenko,V., Magi,R.,
Magnusson,P.K., Marmot,M., Meneton,P., Mohlke,K.L., Mooser,V.,
Morken,M.A., Miljkovic,I., Narisu,N., O'Connell,J., Ong,K.K.,
Oostra,B.A., Palmer,L.J., Palotie,A., Pankow,J.S., Peden,J.F.,
Pedersen,N.L., Pehlic,M., Peltonen,L., Penninx,B., Pericic,M.,
Perola,M., Perusse,L., Peyser,P.A., Polasek,O., Pramstaller,P.P.,
Province,M.A., Raikkonen,K., Rauramaa,R., Rehnberg,E., Rice,K.,
Rotter,J.I., Rudan,I., Ruokonen,A., Saaristo,T., Sabater-Lleal,M.,
Salomaa,V., Savage,D.B., Saxena,R., Schwarz,P., Seedorf,U.,
Sennblad,B., Serrano-Rios,M., Shuldiner,A.R., Sijbrands,E.J.,
Siscovick,D.S., Smit,J.H., Small,K.S., Smith,N.L., Smith,A.V.,
Stancakova,A., Stirrups,K., Stumvoll,M., Sun,Y.V., Swift,A.J.,
Tonjes,A., Tuomilehto,J., Trompet,S., Uitterlinden,A.G.,
Uusitupa,M., Vikstrom,M., Vitart,V., Vohl,M.C., Voight,B.F.,
Vollenweider,P., Waeber,G., Waterworth,D.M., Watkins,H.,
Wheeler,E., Widen,E., Wild,S.H., Willems,S.M., Willemsen,G.,
Wilson,J.F., Witteman,J.C., Wright,A.F., Yaghootkar,H.,
Zelenika,D., Zemunik,T., Zgaga,L., Wareham,N.J., McCarthy,M.I.,
Barroso,I., Watanabe,R.M., Florez,J.C., Dupuis,J., Meigs,J.B. and
Langenberg,C.
CONSRTM DIAbetes Genetics Replication And Meta-analysis (DIAGRAM)
Consortium; Multiple Tissue Human Expression Resource (MUTHER)
Consortium
TITLE A genome-wide approach accounting for body mass index identifies
genetic variants influencing fasting glycemic traits and insulin
resistance
JOURNAL Nat. Genet. 44 (6), 659-669 (2012)
PUBMED 22581228
REMARK Publication Status: Online-Only
REFERENCE 3 (bases 1 to 5716)
AUTHORS Zhang,H., Newman,D.R. and Sannes,P.L.
TITLE HSULF-1 inhibits ERK and AKT signaling and decreases cell viability
in vitro in human lung epithelial cells
JOURNAL Respir. Res. 13, 69 (2012)
PUBMED 22873647
REMARK GeneRIF: HSULF-1 is expressed at lower levels in H292 lung cancer
cells than in normal human alveolar cells and that its
over-expression reduced cell viability in H292 cells by inducing
apoptotic pathways, at least in part by inhibiting ERK/Akt
signaling
Publication Status: Online-Only
REFERENCE 4 (bases 1 to 5716)
AUTHORS Gopal,G., Shirley,S., Raja,U.M. and Rajkumar,T.
TITLE Endo-sulfatase Sulf-1 protein expression is down-regulated in
gastric cancer
JOURNAL Asian Pac. J. Cancer Prev. 13 (2), 641-646 (2012)
PUBMED 22524839
REMARK GeneRIF: Sulf-1 protein expression is down-regulated in gastric
cancer.
REFERENCE 5 (bases 1 to 5716)
AUTHORS N'Diaye,A., Chen,G.K., Palmer,C.D., Ge,B., Tayo,B., Mathias,R.A.,
Ding,J., Nalls,M.A., Adeyemo,A., Adoue,V., Ambrosone,C.B.,
Atwood,L., Bandera,E.V., Becker,L.C., Berndt,S.I., Bernstein,L.,
Blot,W.J., Boerwinkle,E., Britton,A., Casey,G., Chanock,S.J.,
Demerath,E., Deming,S.L., Diver,W.R., Fox,C., Harris,T.B.,
Hernandez,D.G., Hu,J.J., Ingles,S.A., John,E.M., Johnson,C.,
Keating,B., Kittles,R.A., Kolonel,L.N., Kritchevsky,S.B., Le
Marchand,L., Lohman,K., Liu,J., Millikan,R.C., Murphy,A.,
Musani,S., Neslund-Dudas,C., North,K.E., Nyante,S., Ogunniyi,A.,
Ostrander,E.A., Papanicolaou,G., Patel,S., Pettaway,C.A.,
Press,M.F., Redline,S., Rodriguez-Gil,J.L., Rotimi,C.,
Rybicki,B.A., Salako,B., Schreiner,P.J., Signorello,L.B.,
Singleton,A.B., Stanford,J.L., Stram,A.H., Stram,D.O., Strom,S.S.,
Suktitipat,B., Thun,M.J., Witte,J.S., Yanek,L.R., Ziegler,R.G.,
Zheng,W., Zhu,X., Zmuda,J.M., Zonderman,A.B., Evans,M.K., Liu,Y.,
Becker,D.M., Cooper,R.S., Pastinen,T., Henderson,B.E.,
Hirschhorn,J.N., Lettre,G. and Haiman,C.A.
TITLE Identification, replication, and fine-mapping of Loci associated
with adult height in individuals of african ancestry
JOURNAL PLoS Genet. 7 (10), E1002298 (2011)
PUBMED 21998595
REMARK Erratum:[PLoS Genet. 2011 Nov;7(11).
doi:10.1371/annotation/58c67154-3f10-4155-9085-dcd6e3689008]
REFERENCE 6 (bases 1 to 5716)
AUTHORS Dai,Y., Yang,Y., MacLeod,V., Yue,X., Rapraeger,A.C., Shriver,Z.,
Venkataraman,G., Sasisekharan,R. and Sanderson,R.D.
TITLE HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth
in vivo
JOURNAL J. Biol. Chem. 280 (48), 40066-40073 (2005)
PUBMED 16192265
REMARK GeneRIF: HSulf-1 and HSulf-2 have roles in inhibiting myeloma tumor
growth
GeneRIF: HSulf-1 (SULF1) and HSulf-2 (SULF2) are potent inhibitors
of myeloma tumor growth in vivo.
REFERENCE 7 (bases 1 to 5716)
AUTHORS Li,J., Kleeff,J., Abiatari,I., Kayed,H., Giese,N.A., Felix,K.,
Giese,T., Buchler,M.W. and Friess,H.
TITLE Enhanced levels of Hsulf-1 interfere with heparin-binding growth
factor signaling in pancreatic cancer
JOURNAL Mol. Cancer 4 (1), 14 (2005)
PUBMED 15817123
REMARK GeneRIF: High expression of Hsulf-1 occurs in the stromal elements
as well as in the tumor cells in pancreatic cancer and interferes
with heparin-binding growth factor signaling
Publication Status: Online-Only
REFERENCE 8 (bases 1 to 5716)
AUTHORS Lai,J.P., Chien,J.R., Moser,D.R., Staub,J.K., Aderca,I.,
Montoya,D.P., Matthews,T.A., Nagorney,D.M., Cunningham,J.M.,
Smith,D.I., Greene,E.L., Shridhar,V. and Roberts,L.R.
TITLE hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells
by decreasing heparin-binding growth factor signaling
JOURNAL Gastroenterology 126 (1), 231-248 (2004)
PUBMED 14699503
REMARK GeneRIF: Down-regulation of hSulf1 contributes to
hepatocarcinogenesis by enhancing heparin-binding growth factor
signaling and resistance to apoptosis.
REFERENCE 9 (bases 1 to 5716)
AUTHORS Lai,J., Chien,J., Staub,J., Avula,R., Greene,E.L., Matthews,T.A.,
Smith,D.I., Kaufmann,S.H., Roberts,L.R. and Shridhar,V.
TITLE Loss of HSulf-1 up-regulates heparin-binding growth factor
signaling in cancer
JOURNAL J. Biol. Chem. 278 (25), 23107-23117 (2003)
PUBMED 12686563
REMARK GeneRIF: modulates signaling by heparin-binding growth factors, and
HSulf-1 down-regulation represents a novel mechanism by which
cancer cells can enhance growth factor signaling
REFERENCE 10 (bases 1 to 5716)
AUTHORS Morimoto-Tomita,M., Uchimura,K., Werb,Z., Hemmerich,S. and
Rosen,S.D.
TITLE Cloning and characterization of two extracellular heparin-degrading
endosulfatases in mice and humans
JOURNAL J. Biol. Chem. 277 (51), 49175-49185 (2002)
PUBMED 12368295
REMARK GeneRIF: Sulfs are extracellular endosulfatases with strong
potential for modulating the interactions of heparan sulfate
proteoglycans in the extracellular microenvironment
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
DA234578.1, AY101175.1 and AF545571.1.
Summary: Heparan sulfate proteoglycans (HSPGs) act as coreceptors
for numerous heparin-binding growth factors and cytokines and are
involved in cell signaling. Heparan sulfate 6-O-endosulfatases,
such as SULF1, selectively remove 6-O-sulfate groups from heparan
sulfate. This activity modulates the effects of heparan sulfate by
altering binding sites for signaling molecules (Dai et al., 2005
[PubMed 16192265]).[supplied by OMIM, Mar 2008].
Transcript Variant: This variant (1) represents the longest
transcript. Variants 1-4 encode the same protein.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: BX571746.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025083, ERS025084 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-546 DA234578.1 35-580
547-3881 AY101175.1 332-3666
3882-5716 AF545571.1 3865-5699
FEATURES Location/Qualifiers
source 1..5716
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8q13.1"
gene 1..5716
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="sulfatase 1"
/db_xref="GeneID:23213"
/db_xref="HGNC:20391"
/db_xref="MIM:610012"
exon 1..333
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 46
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:191002941"
variation 57
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:183523196"
variation 121
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:2725092"
variation 188
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376975556"
variation 224
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139415692"
variation 301
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:112601068"
variation 302
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:79820523"
variation 311..313
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace=""
/replace="aga"
/db_xref="dbSNP:371632962"
variation 324
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:7840249"
exon 334..495
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 350
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:190710581"
variation 472
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:142022282"
exon 496..590
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 504
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:185882678"
variation 547
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:13264163"
variation 568
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148950847"
exon 591..663
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
misc_feature 655..657
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="upstream in-frame stop codon"
exon 664..895
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 679
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376187821"
variation 714
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:369974279"
CDS 724..3339
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="sulfatase FP; extracellular sulfatase Sulf-1"
/codon_start=1
/product="extracellular sulfatase Sulf-1 precursor"
/protein_id="NP_001121677.1"
/db_xref="GI:189571641"
/db_xref="CCDS:CCDS6204.1"
/db_xref="GeneID:23213"
/db_xref="HGNC:20391"
/db_xref="MIM:610012"
/translation="
MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLLTVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHTRQTRSLSVEFEGEIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLADSSNAVGPPTTVRVTHKCFILPNDSIHCERELYQSARAWKDHKAYIDKEIEALQDKIKNLREVRGHLKRRKPEECSCSKQSYYNKEKGVKKQEKLKSHLHPFKEAAQEVDSKLQLFKENNRRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWCLRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGYKQCNPRPKNLDVGNKDGGSYDLHRGQLWDGWEG
"
sig_peptide 724..789
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="COORDINATES: ab initio prediction:SignalP:4.0"
mat_peptide 790..3336
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/product="Extracellular sulfatase Sulf-1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q8IWU6.1)"
misc_feature 847..>1905
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="Arylsulfatase A and related enzymes [Inorganic ion
transport and metabolism]; Region: AslA; COG3119"
/db_xref="CDD:32933"
misc_feature 850..1902
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="Sulfatase; Region: Sulfatase; pfam00884"
/db_xref="CDD:201490"
misc_feature 2320..2763
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="Sulfatase protein; Region: DUF3740; pfam12548"
/db_xref="CDD:204957"
variation 785
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:201640007"
variation 792
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201650068"
variation 806
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:376825615"
variation 821
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:145127325"
variation 837
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:367922640"
variation 838
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:142027500"
variation 876
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:138943816"
exon 896..1135
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 904
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:199820581"
variation 940
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:201774043"
variation 942
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:141505559"
variation 974
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:113938874"
variation 990
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:6984529"
variation 995
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149786573"
variation 1005
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:377416230"
variation 1011
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:138186217"
variation 1030
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:200955613"
variation 1031
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370346553"
variation 1050
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370128603"
variation 1071
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370291955"
variation 1094
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:147909650"
exon 1136..1287
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1137
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:149562933"
variation 1164
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:371221472"
variation 1183
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:147245253"
variation 1212
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:199957740"
variation 1245
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139810682"
variation 1246
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200127043"
variation 1247
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:186655894"
exon 1288..1457
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1362
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:191906713"
variation 1365
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:374058291"
variation 1392
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:111474126"
variation 1395
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:368146472"
variation 1398
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:77728226"
variation 1434
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372034572"
exon 1458..1608
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1503
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377164865"
variation 1513
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:112367866"
variation 1555
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:202004083"
variation 1572
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:141571826"
variation 1581
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61746702"
exon 1609..1784
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1611
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:142148202"
variation 1668
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201468946"
variation 1692
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:377634023"
variation 1739
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61747207"
exon 1785..1913
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1789
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199804686"
variation 1790
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:374371569"
variation 1798
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:140542311"
variation 1818
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:144010163"
variation 1819
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:201478955"
variation 1824
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:146417849"
variation 1834
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:118056333"
variation 1852
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:201919147"
variation 1855
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:371818580"
variation 1868
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:201782679"
exon 1914..1970
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
exon 1971..2100
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1982
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201100928"
variation 2053
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:145174051"
variation 2094
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:112123068"
variation 2096
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148982651"
exon 2101..2317
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2101
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:199539739"
variation 2115
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:147479634"
variation 2130
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:374949302"
variation 2172
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:367667000"
variation 2182
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372786570"
variation 2190
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148125441"
variation 2192
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:141888575"
variation 2197
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201173589"
variation 2202
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:146435519"
variation 2203
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368427346"
variation 2204
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:112120588"
variation 2206
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:142971465"
variation 2207
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372337091"
variation 2217
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:375512132"
variation 2237
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:369545860"
variation 2250
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200268962"
variation 2252
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372839295"
variation 2258
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:202168144"
variation 2262
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:147223148"
variation 2281
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:374818506"
variation 2286
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368822296"
variation 2312
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139600896"
exon 2318..2573
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2318
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149298828"
variation 2345
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370846825"
variation 2368
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201229545"
variation 2444
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199742300"
variation 2468
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:138876060"
variation 2505
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:370806055"
variation 2510
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144546726"
variation 2512
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61747130"
variation 2531
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:61740823"
variation 2535
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:375090509"
variation 2536
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144030540"
variation 2539
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:146445328"
variation 2543
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:367704931"
variation 2557
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:200550270"
variation 2560
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:370193108"
exon 2574..2670
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2637
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:140509610"
variation 2665
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376608568"
exon 2671..2765
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
exon 2766..2831
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2775
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370172405"
exon 2832..3007
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2865
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:143120352"
variation 2878..2880
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace=""
/replace="aac"
/db_xref="dbSNP:150178205"
variation 2884
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377353091"
variation 2885
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369423636"
variation 2888
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:373878204"
variation 2892
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:143386315"
variation 2894
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:199811211"
variation 2918
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:199542001"
variation 3007
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370600729"
exon 3008..3150
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 3030
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:190311964"
variation 3077
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:150467604"
variation 3110
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:145335171"
variation 3117
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:78063897"
variation 3127
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:74480225"
exon 3151..3274
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 3163
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:117639561"
variation 3170
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:111626231"
variation 3200
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:148555931"
variation 3207
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:146601124"
variation 3216
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368328719"
variation 3254
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:139106228"
variation 3257
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372242544"
variation 3272
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:143009161"
exon 3275..3308
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 3299
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:143631855"
exon 3309..5716
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 3310
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148285446"
variation 3319
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201165394"
variation 3341
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:141331130"
variation 3493
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369995251"
variation 3520..3523
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace=""
/replace="aaat"
/db_xref="dbSNP:112665345"
variation 3576
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:371124844"
variation 3580
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:112715006"
variation 3604
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:77871693"
variation 3629
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:191954863"
variation 3649
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:111938908"
variation 3668
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:148648757"
variation 3728
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:115563984"
variation 3766
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:183717149"
variation 3775
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:75724852"
variation 3787
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:114581461"
variation 3838
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:72660109"
variation 3848
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:187437769"
variation 3882
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:3802278"
variation 3950
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:59068490"
variation 4032
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139690250"
variation 4036
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:371075932"
variation 4060
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:145279779"
variation 4100
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:6990375"
variation 4144
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:189672278"
variation 4191
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:11996377"
variation 4206
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:1130242"
variation 4281
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372074006"
variation 4305
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:59364549"
variation 4328
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:182489932"
variation 4334
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:76316652"
variation 4442
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:147649872"
variation 4453
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:187129161"
variation 4525
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:374978465"
variation 4541
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:191896243"
variation 4550
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:367559651"
variation 4572
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:183580848"
variation 4637
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:140433867"
STS 4696..4817
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/standard_name="RH47887"
/db_xref="UniSTS:48570"
variation 4703
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:188265806"
variation 4790
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:193164086"
variation 4816
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149994968"
variation 4826
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:185376784"
variation 5042
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:189504583"
variation 5243
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:191238908"
STS 5501..5683
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/standard_name="RH98994"
/db_xref="UniSTS:89243"
variation 5504
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372371432"
variation 5573
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:3087714"
ORIGIN
gtgatgataataatacgcgggcttatataaccgtcttcatcttgcgagcacttcgcagaccgtcgctaatgaatcttggggccggtgtcgggccggggcggcttgatcggcaactaggaaaccccaggcgcagaggccaggagcgagggcagcgaggatcagaggccaggccttcccggctgccggcgctcctcggaggtcagggcagatgaggaacatgactctcccccttcggaggaggaaggaagtcccgctgccaccttatctctgctcctctgcctcctccctgttcccagagctttttctctagagaagattttgaaggcggcttttggattcttcacttctcttgaacaaggaactcactcagagactaacacaaaggaagtaatttcttacctggtcattatttagtctacaataagttcatccttcttcagtgtgaccagtaaattcttcccatactcttgaagagagcataattggaatggagaggtgctgacggccacccaccatcatctaaagaagataaacttggcaaatgacatgcaggttcttcaaggcagaataattgcagaaaatcttcaaaggaccctatctgcagatgttctgaatacctctgagaatagagattgattattcaaccaggatacctaattcaagaactccagaaatcaggagacggagacattttgtcagttttgcaacattggaccaaatacaatgaagtattcttgctgtgctctggttttggctgtcctgggcacagaattgctgggaagcctctgttcgactgtcagatccccgaggttcagaggacggatacagcaggaacgaaaaaacatccgacccaacattattcttgtgcttaccgatgatcaagatgtggagctggggtccctgcaagtcatgaacaaaacgagaaagattatggaacatgggggggccaccttcatcaatgcctttgtgactacacccatgtgctgcccgtcacggtcctccatgctcaccgggaagtatgtgcacaatcacaatgtctacaccaacaacgagaactgctcttccccctcgtggcaggccatgcatgagcctcggacttttgctgtatatcttaacaacactggctacagaacagccttttttggaaaatacctcaatgaatataatggcagctacatcccccctgggtggcgagaatggcttggattaatcaagaattctcgcttctataattacactgtttgtcgcaatggcatcaaagaaaagcatggatttgattatgcaaaggactacttcacagacttaatcactaacgagagcattaattacttcaaaatgtctaagagaatgtatccccataggcccgttatgatggtgatcagccacgctgcgccccacggccccgaggactcagccccacagttttctaaactgtaccccaatgcttcccaacacataactcctagttataactatgcaccaaatatggataaacactggattatgcagtacacaggaccaatgctgcccatccacatggaatttacaaacattctacagcgcaaaaggctccagactttgatgtcagtggatgattctgtggagaggctgtataacatgctcgtggagacgggggagctggagaatacttacatcatttacaccgccgaccatggttaccatattgggcagtttggactggtcaaggggaaatccatgccatatgactttgatattcgtgtgcctttttttattcgtggtccaagtgtagaaccaggatcaatagtcccacagatcgttctcaacattgacttggcccccacgatcctggatattgctgggctcgacacacctcctgatgtggacggcaagtctgtcctcaaacttctggacccagaaaagccaggtaacaggtttcgaacaaacaagaaggccaaaatttggcgtgatacattcctagtggaaagaggcaaatttctacgtaagaaggaagaatccagcaagaatatccaacagtcaaatcacttgcccaaatatgaacgggtcaaagaactatgccagcaggccaggtaccagacagcctgtgaacaaccggggcagaagtggcaatgcattgaggatacatctggcaagcttcgaattcacaagtgtaaaggacccagtgacctgctcacagtccggcagagcacgcggaacctctacgctcgcggcttccatgacaaagacaaagagtgcagttgtagggagtctggttaccgtgccagcagaagccaaagaaagagtcaacggcaattcttgagaaaccaggggactccaaagtacaagcccagatttgtccatactcggcagacacgttccttgtccgtcgaatttgaaggtgaaatatatgacataaatctggaagaagaagaagaattgcaagtgttgcaaccaagaaacattgctaagcgtcatgatgaaggccacaaggggccaagagatctccaggcttccagtggtggcaacaggggcaggatgctggcagatagcagcaacgccgtgggcccacctaccactgtccgagtgacacacaagtgttttattcttcccaatgactctatccattgtgagagagaactgtaccaatcggccagagcgtggaaggaccataaggcatacattgacaaagagattgaagctctgcaagataaaattaagaatttaagagaagtgagaggacatctgaagagaaggaagcctgaggaatgtagctgcagtaaacaaagctattacaataaagagaaaggtgtaaaaaagcaagagaaattaaagagccatcttcacccattcaaggaggctgctcaggaagtagatagcaaactgcaacttttcaaggagaacaaccgtaggaggaagaaggagaggaaggagaagagacggcagaggaagggggaagagtgcagcctgcctggcctcacttgcttcacgcatgacaacaaccactggcagacagccccgttctggaacctgggatctttctgtgcttgcacgagttctaacaataacacctactggtgtttgcgtacagttaatgagacgcataattttcttttctgtgagtttgctactggctttttggagtattttgatatgaatacagatccttatcagctcacaaatacagtgcacacggtagaacgaggcattttgaatcagctacacgtacaactaatggagctcagaagctgtcaaggatataagcagtgcaacccaagacctaagaatcttgatgttggaaataaagatggaggaagctatgacctacacagaggacagttatgggatggatgggaaggttaatcagccccgtctcactgcagacatcaactggcaaggcctagaggagctacacagtgtgaatgaaaacatctatgagtacagacaaaactacagacttagtctggtggactggactaattacttgaaggatttagatagagtatttgcactgctgaagagtcactatgagcaaaataaaacaaataagactcaaactgctcaaagtgacgggttcttggttgtctctgctgagcacgctgtgtcaatggagatggcctctgctgactcagatgaagacccaaggcataaggttgggaaaacacctcatttgaccttgccagctgaccttcaaaccctgcatttgaaccgaccaacattaagtccagagagtaaacttgaatggaataacgacattccagaagttaatcatttgaattctgaacactggagaaaaaccgaaaaatggacggggcatgaagagactaatcatctggaaaccgatttcagtggcgatggcatgacagagctagagctcgggcccagccccaggctgcagcccattcgcaggcacccgaaagaacttccccagtatggtggtcctggaaaggacatttttgaagatcaactatatcttcctgtgcattccgatggaatttcagttcatcagatgttcaccatggccaccgcagaacaccgaagtaattccagcatagcggggaagatgttgaccaaggtggagaagaatcacgaaaaggagaagtcacagcacctagaaggcagcgcctcctcttcactctcctctgattagatgaaactgttaccttaccctaaacacagtatttctttttaacttttttatttgtaaactaataaaggtaatcacagccaccaacattccaagctaccctgggtacctttgtgcagtagaagctagtgagcatgtgagcaagcggtgtgcacacggagactcatcgttataatttactatctgccaagagtagaaagaaaggctggggatatttgggttggcttggttttgattttttgcttgtttgtttgttttgtactaaaacagtattatcttttgaatatcgtagggacataagtatatacatgttatccaatcaagatggctagaatggtgcctttctgagtgtctaaaacttgacacccctggtaaatctttcaacacacttccactgcctgcgtaatgaagttttgattcatttttaaccactggaatttttcaatgccgtcattttcagttagatgattttgcactttgagattaaaatgccatgtctatttgattagtcttatttttttatttttacaggcttatcagtctcactgttggctgtcattgtgacaaagtcaaataaacccccaaggacgacacacagtatggatcacatattgtttgacattaagcttttgccagaaaatgttgcatgtgttttacctcgacttgctaaaatcgattagcagaaaggcatggctaataatgttggtggtgaaaataaataaataagtaaacaaaatgaagattgcctgctctctctgtgcctagcctcaaagcgttcatcatacatcatacctttaagattgctatattttgggttattttcttgacaggagaaaaagatctaaagatcttttattttcatcttttttggttttcttggcatgactaagaagcttaaatgttgataaaatatgactagttttgaatttacaccaagaacttctcaataaaagaaaatcatgaatgctccacaatttcaacataccacaagagaagttaatttcttaacattgtgttctatgattatttgtaagaccttcaccaagttctgatatcttttaaagacatagttcaaaattgcttttgaaaatctgtattcttgaaaatatccttgttgtgtattaggtttttaaataccagctaaaggattacctcactgagtcatcagtaccctcctattcagctccccaagatgatgtgtttttgcttaccctaagagaggttttcttcttatttttagataattcaagtgcttagataaattatgttttctttaagtgtttatggtaaactcttttaaagaaaatttaatatgttatagctgaatctttttggtaactttaaatctttatcatagactctgtacatatgttcaaattagctgcttgcctgatgtgtgtatcatcggtgggatgacagaacaaacatatttatgatcatgaataatgtgctttgtaaaaagatttcaagttattaggaagcatactctgttttttaatcatgtataatattccatgatacttttatagaacaattctggcttcaggaaagtctagaagcaatatttcttcaaataaaaggtgtttaaacttt
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:23213 -> Molecular function: GO:0004065 [arylsulfatase activity] evidence: IDA
GeneID:23213 -> Molecular function: GO:0004065 [arylsulfatase activity] evidence: IMP
GeneID:23213 -> Molecular function: GO:0005509 [calcium ion binding] evidence: IEA
GeneID:23213 -> Molecular function: GO:0008449 [N-acetylglucosamine-6-sulfatase activity] evidence: IDA
GeneID:23213 -> Molecular function: GO:0008449 [N-acetylglucosamine-6-sulfatase activity] evidence: IMP
GeneID:23213 -> Biological process: GO:0001822 [kidney development] evidence: ISS
GeneID:23213 -> Biological process: GO:0001937 [negative regulation of endothelial cell proliferation] evidence: IDA
GeneID:23213 -> Biological process: GO:0002063 [chondrocyte development] evidence: ISS
GeneID:23213 -> Biological process: GO:0003094 [glomerular filtration] evidence: ISS
GeneID:23213 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:23213 -> Biological process: GO:0010575 [positive regulation vascular endothelial growth factor production] evidence: ISS
GeneID:23213 -> Biological process: GO:0014846 [esophagus smooth muscle contraction] evidence: ISS
GeneID:23213 -> Biological process: GO:0016525 [negative regulation of angiogenesis] evidence: IDA
GeneID:23213 -> Biological process: GO:0030177 [positive regulation of Wnt receptor signaling pathway] evidence: IDA
GeneID:23213 -> Biological process: GO:0030201 [heparan sulfate proteoglycan metabolic process] evidence: IDA
GeneID:23213 -> Biological process: GO:0030201 [heparan sulfate proteoglycan metabolic process] evidence: NAS
GeneID:23213 -> Biological process: GO:0030336 [negative regulation of cell migration] evidence: IMP
GeneID:23213 -> Biological process: GO:0030513 [positive regulation of BMP signaling pathway] evidence: IMP
GeneID:23213 -> Biological process: GO:0032836 [glomerular basement membrane development] evidence: ISS
GeneID:23213 -> Biological process: GO:0035860 [glial cell-derived neurotrophic factor receptor signaling pathway] evidence: ISS
GeneID:23213 -> Biological process: GO:0040036 [regulation of fibroblast growth factor receptor signaling pathway] evidence: IMP
GeneID:23213 -> Biological process: GO:0040037 [negative regulation of fibroblast growth factor receptor signaling pathway] evidence: IMP
GeneID:23213 -> Biological process: GO:0040037 [negative regulation of fibroblast growth factor receptor signaling pathway] evidence: ISS
GeneID:23213 -> Biological process: GO:0048010 [vascular endothelial growth factor receptor signaling pathway] evidence: IDA
GeneID:23213 -> Biological process: GO:0048706 [embryonic skeletal system development] evidence: ISS
GeneID:23213 -> Biological process: GO:0051216 [cartilage development] evidence: ISS
GeneID:23213 -> Biological process: GO:0060348 [bone development] evidence: ISS
GeneID:23213 -> Biological process: GO:0060384 [innervation] evidence: ISS
GeneID:23213 -> Biological process: GO:0060686 [negative regulation of prostatic bud formation] evidence: ISS
GeneID:23213 -> Cellular component: GO:0005615 [extracellular space] evidence: IDA
GeneID:23213 -> Cellular component: GO:0005615 [extracellular space] evidence: NAS
GeneID:23213 -> Cellular component: GO:0005783 [endoplasmic reticulum] evidence: IDA
GeneID:23213 -> Cellular component: GO:0005794 [Golgi apparatus] evidence: ISS
GeneID:23213 -> Cellular component: GO:0005795 [Golgi stack] evidence: IEA
GeneID:23213 -> Cellular component: GO:0005886 [plasma membrane] evidence: ISS
GeneID:23213 -> Cellular component: GO:0009986 [cell surface] evidence: IDA
GeneID:23213 -> Cellular component: GO:0045121 [membrane raft] evidence: IDA
by
@meso_cacase at
DBCLS
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