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2024-04-19 17:52:10, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001128204 5548 bp mRNA linear PRI 12-MAY-2013
DEFINITION Homo sapiens sulfatase 1 (SULF1), transcript variant 4, mRNA.
ACCESSION NM_001128204
VERSION NM_001128204.1 GI:189571637
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5548)
AUTHORS Hur,K., Han,T.S., Jung,E.J., Yu,J., Lee,H.J., Kim,W.H., Goel,A. and
Yang,H.K.
TITLE Up-regulated expression of sulfatases (SULF1 and SULF2) as
prognostic and metastasis predictive markers in human gastric
cancer
JOURNAL J. Pathol. 228 (1), 88-98 (2012)
PUBMED 22653794
REMARK GeneRIF: SULF1 may serve as a promising biomarker for patients with
gastric carcinoma.
REFERENCE 2 (bases 1 to 5548)
AUTHORS Manning,A.K., Hivert,M.F., Scott,R.A., Grimsby,J.L.,
Bouatia-Naji,N., Chen,H., Rybin,D., Liu,C.T., Bielak,L.F.,
Prokopenko,I., Amin,N., Barnes,D., Cadby,G., Hottenga,J.J.,
Ingelsson,E., Jackson,A.U., Johnson,T., Kanoni,S., Ladenvall,C.,
Lagou,V., Lahti,J., Lecoeur,C., Liu,Y., Martinez-Larrad,M.T.,
Montasser,M.E., Navarro,P., Perry,J.R., Rasmussen-Torvik,L.J.,
Salo,P., Sattar,N., Shungin,D., Strawbridge,R.J., Tanaka,T., van
Duijn,C.M., An,P., de Andrade,M., Andrews,J.S., Aspelund,T.,
Atalay,M., Aulchenko,Y., Balkau,B., Bandinelli,S., Beckmann,J.S.,
Beilby,J.P., Bellis,C., Bergman,R.N., Blangero,J., Boban,M.,
Boehnke,M., Boerwinkle,E., Bonnycastle,L.L., Boomsma,D.I.,
Borecki,I.B., Bottcher,Y., Bouchard,C., Brunner,E., Budimir,D.,
Campbell,H., Carlson,O., Chines,P.S., Clarke,R., Collins,F.S.,
Corbaton-Anchuelo,A., Couper,D., de Faire,U., Dedoussis,G.V.,
Deloukas,P., Dimitriou,M., Egan,J.M., Eiriksdottir,G., Erdos,M.R.,
Eriksson,J.G., Eury,E., Ferrucci,L., Ford,I., Forouhi,N.G.,
Fox,C.S., Franzosi,M.G., Franks,P.W., Frayling,T.M., Froguel,P.,
Galan,P., de Geus,E., Gigante,B., Glazer,N.L., Goel,A., Groop,L.,
Gudnason,V., Hallmans,G., Hamsten,A., Hansson,O., Harris,T.B.,
Hayward,C., Heath,S., Hercberg,S., Hicks,A.A., Hingorani,A.,
Hofman,A., Hui,J., Hung,J., Jarvelin,M.R., Jhun,M.A., Johnson,P.C.,
Jukema,J.W., Jula,A., Kao,W.H., Kaprio,J., Kardia,S.L.,
Keinanen-Kiukaanniemi,S., Kivimaki,M., Kolcic,I., Kovacs,P.,
Kumari,M., Kuusisto,J., Kyvik,K.O., Laakso,M., Lakka,T.,
Lannfelt,L., Lathrop,G.M., Launer,L.J., Leander,K., Li,G., Lind,L.,
Lindstrom,J., Lobbens,S., Loos,R.J., Luan,J., Lyssenko,V., Magi,R.,
Magnusson,P.K., Marmot,M., Meneton,P., Mohlke,K.L., Mooser,V.,
Morken,M.A., Miljkovic,I., Narisu,N., O'Connell,J., Ong,K.K.,
Oostra,B.A., Palmer,L.J., Palotie,A., Pankow,J.S., Peden,J.F.,
Pedersen,N.L., Pehlic,M., Peltonen,L., Penninx,B., Pericic,M.,
Perola,M., Perusse,L., Peyser,P.A., Polasek,O., Pramstaller,P.P.,
Province,M.A., Raikkonen,K., Rauramaa,R., Rehnberg,E., Rice,K.,
Rotter,J.I., Rudan,I., Ruokonen,A., Saaristo,T., Sabater-Lleal,M.,
Salomaa,V., Savage,D.B., Saxena,R., Schwarz,P., Seedorf,U.,
Sennblad,B., Serrano-Rios,M., Shuldiner,A.R., Sijbrands,E.J.,
Siscovick,D.S., Smit,J.H., Small,K.S., Smith,N.L., Smith,A.V.,
Stancakova,A., Stirrups,K., Stumvoll,M., Sun,Y.V., Swift,A.J.,
Tonjes,A., Tuomilehto,J., Trompet,S., Uitterlinden,A.G.,
Uusitupa,M., Vikstrom,M., Vitart,V., Vohl,M.C., Voight,B.F.,
Vollenweider,P., Waeber,G., Waterworth,D.M., Watkins,H.,
Wheeler,E., Widen,E., Wild,S.H., Willems,S.M., Willemsen,G.,
Wilson,J.F., Witteman,J.C., Wright,A.F., Yaghootkar,H.,
Zelenika,D., Zemunik,T., Zgaga,L., Wareham,N.J., McCarthy,M.I.,
Barroso,I., Watanabe,R.M., Florez,J.C., Dupuis,J., Meigs,J.B. and
Langenberg,C.
CONSRTM DIAbetes Genetics Replication And Meta-analysis (DIAGRAM)
Consortium; Multiple Tissue Human Expression Resource (MUTHER)
Consortium
TITLE A genome-wide approach accounting for body mass index identifies
genetic variants influencing fasting glycemic traits and insulin
resistance
JOURNAL Nat. Genet. 44 (6), 659-669 (2012)
PUBMED 22581228
REMARK Publication Status: Online-Only
REFERENCE 3 (bases 1 to 5548)
AUTHORS Zhang,H., Newman,D.R. and Sannes,P.L.
TITLE HSULF-1 inhibits ERK and AKT signaling and decreases cell viability
in vitro in human lung epithelial cells
JOURNAL Respir. Res. 13, 69 (2012)
PUBMED 22873647
REMARK GeneRIF: HSULF-1 is expressed at lower levels in H292 lung cancer
cells than in normal human alveolar cells and that its
over-expression reduced cell viability in H292 cells by inducing
apoptotic pathways, at least in part by inhibiting ERK/Akt
signaling
Publication Status: Online-Only
REFERENCE 4 (bases 1 to 5548)
AUTHORS Gopal,G., Shirley,S., Raja,U.M. and Rajkumar,T.
TITLE Endo-sulfatase Sulf-1 protein expression is down-regulated in
gastric cancer
JOURNAL Asian Pac. J. Cancer Prev. 13 (2), 641-646 (2012)
PUBMED 22524839
REMARK GeneRIF: Sulf-1 protein expression is down-regulated in gastric
cancer.
REFERENCE 5 (bases 1 to 5548)
AUTHORS N'Diaye,A., Chen,G.K., Palmer,C.D., Ge,B., Tayo,B., Mathias,R.A.,
Ding,J., Nalls,M.A., Adeyemo,A., Adoue,V., Ambrosone,C.B.,
Atwood,L., Bandera,E.V., Becker,L.C., Berndt,S.I., Bernstein,L.,
Blot,W.J., Boerwinkle,E., Britton,A., Casey,G., Chanock,S.J.,
Demerath,E., Deming,S.L., Diver,W.R., Fox,C., Harris,T.B.,
Hernandez,D.G., Hu,J.J., Ingles,S.A., John,E.M., Johnson,C.,
Keating,B., Kittles,R.A., Kolonel,L.N., Kritchevsky,S.B., Le
Marchand,L., Lohman,K., Liu,J., Millikan,R.C., Murphy,A.,
Musani,S., Neslund-Dudas,C., North,K.E., Nyante,S., Ogunniyi,A.,
Ostrander,E.A., Papanicolaou,G., Patel,S., Pettaway,C.A.,
Press,M.F., Redline,S., Rodriguez-Gil,J.L., Rotimi,C.,
Rybicki,B.A., Salako,B., Schreiner,P.J., Signorello,L.B.,
Singleton,A.B., Stanford,J.L., Stram,A.H., Stram,D.O., Strom,S.S.,
Suktitipat,B., Thun,M.J., Witte,J.S., Yanek,L.R., Ziegler,R.G.,
Zheng,W., Zhu,X., Zmuda,J.M., Zonderman,A.B., Evans,M.K., Liu,Y.,
Becker,D.M., Cooper,R.S., Pastinen,T., Henderson,B.E.,
Hirschhorn,J.N., Lettre,G. and Haiman,C.A.
TITLE Identification, replication, and fine-mapping of Loci associated
with adult height in individuals of african ancestry
JOURNAL PLoS Genet. 7 (10), E1002298 (2011)
PUBMED 21998595
REMARK Erratum:[PLoS Genet. 2011 Nov;7(11).
doi:10.1371/annotation/58c67154-3f10-4155-9085-dcd6e3689008]
REFERENCE 6 (bases 1 to 5548)
AUTHORS Dai,Y., Yang,Y., MacLeod,V., Yue,X., Rapraeger,A.C., Shriver,Z.,
Venkataraman,G., Sasisekharan,R. and Sanderson,R.D.
TITLE HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth
in vivo
JOURNAL J. Biol. Chem. 280 (48), 40066-40073 (2005)
PUBMED 16192265
REMARK GeneRIF: HSulf-1 and HSulf-2 have roles in inhibiting myeloma tumor
growth
GeneRIF: HSulf-1 (SULF1) and HSulf-2 (SULF2) are potent inhibitors
of myeloma tumor growth in vivo.
REFERENCE 7 (bases 1 to 5548)
AUTHORS Li,J., Kleeff,J., Abiatari,I., Kayed,H., Giese,N.A., Felix,K.,
Giese,T., Buchler,M.W. and Friess,H.
TITLE Enhanced levels of Hsulf-1 interfere with heparin-binding growth
factor signaling in pancreatic cancer
JOURNAL Mol. Cancer 4 (1), 14 (2005)
PUBMED 15817123
REMARK GeneRIF: High expression of Hsulf-1 occurs in the stromal elements
as well as in the tumor cells in pancreatic cancer and interferes
with heparin-binding growth factor signaling
Publication Status: Online-Only
REFERENCE 8 (bases 1 to 5548)
AUTHORS Lai,J.P., Chien,J.R., Moser,D.R., Staub,J.K., Aderca,I.,
Montoya,D.P., Matthews,T.A., Nagorney,D.M., Cunningham,J.M.,
Smith,D.I., Greene,E.L., Shridhar,V. and Roberts,L.R.
TITLE hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells
by decreasing heparin-binding growth factor signaling
JOURNAL Gastroenterology 126 (1), 231-248 (2004)
PUBMED 14699503
REMARK GeneRIF: Down-regulation of hSulf1 contributes to
hepatocarcinogenesis by enhancing heparin-binding growth factor
signaling and resistance to apoptosis.
REFERENCE 9 (bases 1 to 5548)
AUTHORS Lai,J., Chien,J., Staub,J., Avula,R., Greene,E.L., Matthews,T.A.,
Smith,D.I., Kaufmann,S.H., Roberts,L.R. and Shridhar,V.
TITLE Loss of HSulf-1 up-regulates heparin-binding growth factor
signaling in cancer
JOURNAL J. Biol. Chem. 278 (25), 23107-23117 (2003)
PUBMED 12686563
REMARK GeneRIF: modulates signaling by heparin-binding growth factors, and
HSulf-1 down-regulation represents a novel mechanism by which
cancer cells can enhance growth factor signaling
REFERENCE 10 (bases 1 to 5548)
AUTHORS Morimoto-Tomita,M., Uchimura,K., Werb,Z., Hemmerich,S. and
Rosen,S.D.
TITLE Cloning and characterization of two extracellular heparin-degrading
endosulfatases in mice and humans
JOURNAL J. Biol. Chem. 277 (51), 49175-49185 (2002)
PUBMED 12368295
REMARK GeneRIF: Sulfs are extracellular endosulfatases with strong
potential for modulating the interactions of heparan sulfate
proteoglycans in the extracellular microenvironment
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AK095341.1, AY101175.1 and AF545571.1.
Summary: Heparan sulfate proteoglycans (HSPGs) act as coreceptors
for numerous heparin-binding growth factors and cytokines and are
involved in cell signaling. Heparan sulfate 6-O-endosulfatases,
such as SULF1, selectively remove 6-O-sulfate groups from heparan
sulfate. This activity modulates the effects of heparan sulfate by
altering binding sites for signaling molecules (Dai et al., 2005
[PubMed 16192265]).[supplied by OMIM, Mar 2008].
Transcript Variant: This variant (4) differs in the 5' UTR compared
to variant 1. Variants 1-4 encode the same protein.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AK307951.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
ERS025083, ERS025084 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-538 AK095341.1 1-538
539-3713 AY101175.1 492-3666
3714-5548 AF545571.1 3865-5699
FEATURES Location/Qualifiers
source 1..5548
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="8"
/map="8q13.1"
gene 1..5548
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="sulfatase 1"
/db_xref="GeneID:23213"
/db_xref="HGNC:20391"
/db_xref="MIM:610012"
exon 1..327
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 108
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:372014979"
variation 125
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376584503"
variation 176
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:187842089"
exon 328..422
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 336
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:185882678"
variation 379
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:13264163"
variation 400
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148950847"
exon 423..495
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
misc_feature 487..489
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="upstream in-frame stop codon"
exon 496..727
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 511
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376187821"
variation 546
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:369974279"
CDS 556..3171
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="sulfatase FP; extracellular sulfatase Sulf-1"
/codon_start=1
/product="extracellular sulfatase Sulf-1 precursor"
/protein_id="NP_001121676.1"
/db_xref="GI:189571638"
/db_xref="CCDS:CCDS6204.1"
/db_xref="GeneID:23213"
/db_xref="HGNC:20391"
/db_xref="MIM:610012"
/translation="
MKYSCCALVLAVLGTELLGSLCSTVRSPRFRGRIQQERKNIRPNIILVLTDDQDVELGSLQVMNKTRKIMEHGGATFINAFVTTPMCCPSRSSMLTGKYVHNHNVYTNNENCSSPSWQAMHEPRTFAVYLNNTGYRTAFFGKYLNEYNGSYIPPGWREWLGLIKNSRFYNYTVCRNGIKEKHGFDYAKDYFTDLITNESINYFKMSKRMYPHRPVMMVISHAAPHGPEDSAPQFSKLYPNASQHITPSYNYAPNMDKHWIMQYTGPMLPIHMEFTNILQRKRLQTLMSVDDSVERLYNMLVETGELENTYIIYTADHGYHIGQFGLVKGKSMPYDFDIRVPFFIRGPSVEPGSIVPQIVLNIDLAPTILDIAGLDTPPDVDGKSVLKLLDPEKPGNRFRTNKKAKIWRDTFLVERGKFLRKKEESSKNIQQSNHLPKYERVKELCQQARYQTACEQPGQKWQCIEDTSGKLRIHKCKGPSDLLTVRQSTRNLYARGFHDKDKECSCRESGYRASRSQRKSQRQFLRNQGTPKYKPRFVHTRQTRSLSVEFEGEIYDINLEEEEELQVLQPRNIAKRHDEGHKGPRDLQASSGGNRGRMLADSSNAVGPPTTVRVTHKCFILPNDSIHCERELYQSARAWKDHKAYIDKEIEALQDKIKNLREVRGHLKRRKPEECSCSKQSYYNKEKGVKKQEKLKSHLHPFKEAAQEVDSKLQLFKENNRRRKKERKEKRRQRKGEECSLPGLTCFTHDNNHWQTAPFWNLGSFCACTSSNNNTYWCLRTVNETHNFLFCEFATGFLEYFDMNTDPYQLTNTVHTVERGILNQLHVQLMELRSCQGYKQCNPRPKNLDVGNKDGGSYDLHRGQLWDGWEG
"
sig_peptide 556..621
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="COORDINATES: ab initio prediction:SignalP:4.0"
mat_peptide 622..3168
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/product="Extracellular sulfatase Sulf-1"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q8IWU6.1)"
misc_feature 679..>1737
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="Arylsulfatase A and related enzymes [Inorganic ion
transport and metabolism]; Region: AslA; COG3119"
/db_xref="CDD:32933"
misc_feature 682..1734
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="Sulfatase; Region: Sulfatase; pfam00884"
/db_xref="CDD:201490"
misc_feature 2152..2595
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/note="Sulfatase protein; Region: DUF3740; pfam12548"
/db_xref="CDD:204957"
variation 617
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:201640007"
variation 624
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201650068"
variation 638
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:376825615"
variation 653
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:145127325"
variation 669
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:367922640"
variation 670
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:142027500"
variation 708
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:138943816"
exon 728..967
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 736
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:199820581"
variation 772
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:201774043"
variation 774
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:141505559"
variation 806
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:113938874"
variation 822
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:6984529"
variation 827
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149786573"
variation 837
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:377416230"
variation 843
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:138186217"
variation 862
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:200955613"
variation 863
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370346553"
variation 882
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370128603"
variation 903
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370291955"
variation 926
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:147909650"
exon 968..1119
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 969
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:149562933"
variation 996
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:371221472"
variation 1015
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:147245253"
variation 1044
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:199957740"
variation 1077
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139810682"
variation 1078
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200127043"
variation 1079
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:186655894"
exon 1120..1289
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1194
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:191906713"
variation 1197
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:374058291"
variation 1224
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:111474126"
variation 1227
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:368146472"
variation 1230
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:77728226"
variation 1266
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372034572"
exon 1290..1440
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1335
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377164865"
variation 1345
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:112367866"
variation 1387
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:202004083"
variation 1404
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:141571826"
variation 1413
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61746702"
exon 1441..1616
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1443
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:142148202"
variation 1500
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201468946"
variation 1524
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:377634023"
variation 1571
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61747207"
exon 1617..1745
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1621
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199804686"
variation 1622
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:374371569"
variation 1630
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:140542311"
variation 1650
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:144010163"
variation 1651
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:201478955"
variation 1656
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:146417849"
variation 1666
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:118056333"
variation 1684
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:201919147"
variation 1687
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:371818580"
variation 1700
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:201782679"
exon 1746..1802
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
exon 1803..1932
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1814
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201100928"
variation 1885
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:145174051"
variation 1926
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:112123068"
variation 1928
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148982651"
exon 1933..2149
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 1933
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:199539739"
variation 1947
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:147479634"
variation 1962
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:374949302"
variation 2004
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:367667000"
variation 2014
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372786570"
variation 2022
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148125441"
variation 2024
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:141888575"
variation 2029
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201173589"
variation 2034
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:146435519"
variation 2035
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368427346"
variation 2036
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:112120588"
variation 2038
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:142971465"
variation 2039
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372337091"
variation 2049
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:375512132"
variation 2069
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:369545860"
variation 2082
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:200268962"
variation 2084
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372839295"
variation 2090
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:202168144"
variation 2094
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:147223148"
variation 2113
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:374818506"
variation 2118
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368822296"
variation 2144
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139600896"
exon 2150..2405
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2150
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149298828"
variation 2177
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:370846825"
variation 2200
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:201229545"
variation 2276
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:199742300"
variation 2300
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:138876060"
variation 2337
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:370806055"
variation 2342
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144546726"
variation 2344
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:61747130"
variation 2363
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:61740823"
variation 2367
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:375090509"
variation 2368
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:144030540"
variation 2371
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:146445328"
variation 2375
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:367704931"
variation 2389
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:200550270"
variation 2392
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:370193108"
exon 2406..2502
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2469
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:140509610"
variation 2497
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:376608568"
exon 2503..2597
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
exon 2598..2663
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2607
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370172405"
exon 2664..2839
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2697
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:143120352"
variation 2710..2712
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace=""
/replace="aac"
/db_xref="dbSNP:150178205"
variation 2716
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:377353091"
variation 2717
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369423636"
variation 2720
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:373878204"
variation 2724
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:143386315"
variation 2726
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:199811211"
variation 2750
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:199542001"
variation 2839
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:370600729"
exon 2840..2982
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2862
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:190311964"
variation 2909
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:150467604"
variation 2942
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:145335171"
variation 2949
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:78063897"
variation 2959
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:74480225"
exon 2983..3106
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 2995
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:117639561"
variation 3002
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:111626231"
variation 3032
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:148555931"
variation 3039
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:146601124"
variation 3048
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:368328719"
variation 3086
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:139106228"
variation 3089
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372242544"
variation 3104
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:143009161"
exon 3107..3140
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 3131
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:143631855"
exon 3141..5548
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/inference="alignment:Splign:1.39.8"
variation 3142
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:148285446"
variation 3151
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:201165394"
variation 3173
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:141331130"
variation 3325
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:369995251"
variation 3352..3355
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace=""
/replace="aaat"
/db_xref="dbSNP:112665345"
variation 3408
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:371124844"
variation 3412
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:112715006"
variation 3436
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:77871693"
variation 3461
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:191954863"
variation 3481
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:111938908"
variation 3500
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:148648757"
variation 3560
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:115563984"
variation 3598
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:183717149"
variation 3607
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:75724852"
variation 3619
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:114581461"
variation 3670
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:72660109"
variation 3680
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:187437769"
variation 3714
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:3802278"
variation 3782
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:59068490"
variation 3864
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:139690250"
variation 3868
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:371075932"
variation 3892
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:145279779"
variation 3932
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:6990375"
variation 3976
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:189672278"
variation 4023
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:11996377"
variation 4038
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:1130242"
variation 4113
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:372074006"
variation 4137
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:59364549"
variation 4160
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:182489932"
variation 4166
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:76316652"
variation 4274
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:147649872"
variation 4285
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:187129161"
variation 4357
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:374978465"
variation 4373
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:191896243"
variation 4382
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:367559651"
variation 4404
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:183580848"
variation 4469
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:140433867"
STS 4528..4649
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/standard_name="RH47887"
/db_xref="UniSTS:48570"
variation 4535
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:188265806"
variation 4622
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="c"
/db_xref="dbSNP:193164086"
variation 4648
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:149994968"
variation 4658
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="g"
/replace="t"
/db_xref="dbSNP:185376784"
variation 4874
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="g"
/db_xref="dbSNP:189504583"
variation 5075
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="a"
/replace="t"
/db_xref="dbSNP:191238908"
STS 5333..5515
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/standard_name="RH98994"
/db_xref="UniSTS:89243"
variation 5336
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="g"
/db_xref="dbSNP:372371432"
variation 5405
/gene="SULF1"
/gene_synonym="HSULF-1; SULF-1"
/replace="c"
/replace="t"
/db_xref="dbSNP:3087714"
ORIGIN
aggttacttgactgggagttctcagacctccagtttcagccctgccctcagcctccaatccgtaagagacacccagccccagcaattggattgggcagcccgtcttgacacaccactgtgctgagtgcttgaggacgtgtttcaacagatggttggggttagtgtgtgtcatcacattcgagtggggattaagagaaggaaggctgccttgctggagctgtgtggtcttctccaagtgagagtcgcaggcaatagaactactttgcttttggaggaaaaggaggaattcattttcagcagacacaagaaaagcagtttttttttcaggtgctgacggccacccaccatcatctaaagaagataaacttggcaaatgacatgcaggttcttcaaggcagaataattgcagaaaatcttcaaaggaccctatctgcagatgttctgaatacctctgagaatagagattgattattcaaccaggatacctaattcaagaactccagaaatcaggagacggagacattttgtcagttttgcaacattggaccaaatacaatgaagtattcttgctgtgctctggttttggctgtcctgggcacagaattgctgggaagcctctgttcgactgtcagatccccgaggttcagaggacggatacagcaggaacgaaaaaacatccgacccaacattattcttgtgcttaccgatgatcaagatgtggagctggggtccctgcaagtcatgaacaaaacgagaaagattatggaacatgggggggccaccttcatcaatgcctttgtgactacacccatgtgctgcccgtcacggtcctccatgctcaccgggaagtatgtgcacaatcacaatgtctacaccaacaacgagaactgctcttccccctcgtggcaggccatgcatgagcctcggacttttgctgtatatcttaacaacactggctacagaacagccttttttggaaaatacctcaatgaatataatggcagctacatcccccctgggtggcgagaatggcttggattaatcaagaattctcgcttctataattacactgtttgtcgcaatggcatcaaagaaaagcatggatttgattatgcaaaggactacttcacagacttaatcactaacgagagcattaattacttcaaaatgtctaagagaatgtatccccataggcccgttatgatggtgatcagccacgctgcgccccacggccccgaggactcagccccacagttttctaaactgtaccccaatgcttcccaacacataactcctagttataactatgcaccaaatatggataaacactggattatgcagtacacaggaccaatgctgcccatccacatggaatttacaaacattctacagcgcaaaaggctccagactttgatgtcagtggatgattctgtggagaggctgtataacatgctcgtggagacgggggagctggagaatacttacatcatttacaccgccgaccatggttaccatattgggcagtttggactggtcaaggggaaatccatgccatatgactttgatattcgtgtgcctttttttattcgtggtccaagtgtagaaccaggatcaatagtcccacagatcgttctcaacattgacttggcccccacgatcctggatattgctgggctcgacacacctcctgatgtggacggcaagtctgtcctcaaacttctggacccagaaaagccaggtaacaggtttcgaacaaacaagaaggccaaaatttggcgtgatacattcctagtggaaagaggcaaatttctacgtaagaaggaagaatccagcaagaatatccaacagtcaaatcacttgcccaaatatgaacgggtcaaagaactatgccagcaggccaggtaccagacagcctgtgaacaaccggggcagaagtggcaatgcattgaggatacatctggcaagcttcgaattcacaagtgtaaaggacccagtgacctgctcacagtccggcagagcacgcggaacctctacgctcgcggcttccatgacaaagacaaagagtgcagttgtagggagtctggttaccgtgccagcagaagccaaagaaagagtcaacggcaattcttgagaaaccaggggactccaaagtacaagcccagatttgtccatactcggcagacacgttccttgtccgtcgaatttgaaggtgaaatatatgacataaatctggaagaagaagaagaattgcaagtgttgcaaccaagaaacattgctaagcgtcatgatgaaggccacaaggggccaagagatctccaggcttccagtggtggcaacaggggcaggatgctggcagatagcagcaacgccgtgggcccacctaccactgtccgagtgacacacaagtgttttattcttcccaatgactctatccattgtgagagagaactgtaccaatcggccagagcgtggaaggaccataaggcatacattgacaaagagattgaagctctgcaagataaaattaagaatttaagagaagtgagaggacatctgaagagaaggaagcctgaggaatgtagctgcagtaaacaaagctattacaataaagagaaaggtgtaaaaaagcaagagaaattaaagagccatcttcacccattcaaggaggctgctcaggaagtagatagcaaactgcaacttttcaaggagaacaaccgtaggaggaagaaggagaggaaggagaagagacggcagaggaagggggaagagtgcagcctgcctggcctcacttgcttcacgcatgacaacaaccactggcagacagccccgttctggaacctgggatctttctgtgcttgcacgagttctaacaataacacctactggtgtttgcgtacagttaatgagacgcataattttcttttctgtgagtttgctactggctttttggagtattttgatatgaatacagatccttatcagctcacaaatacagtgcacacggtagaacgaggcattttgaatcagctacacgtacaactaatggagctcagaagctgtcaaggatataagcagtgcaacccaagacctaagaatcttgatgttggaaataaagatggaggaagctatgacctacacagaggacagttatgggatggatgggaaggttaatcagccccgtctcactgcagacatcaactggcaaggcctagaggagctacacagtgtgaatgaaaacatctatgagtacagacaaaactacagacttagtctggtggactggactaattacttgaaggatttagatagagtatttgcactgctgaagagtcactatgagcaaaataaaacaaataagactcaaactgctcaaagtgacgggttcttggttgtctctgctgagcacgctgtgtcaatggagatggcctctgctgactcagatgaagacccaaggcataaggttgggaaaacacctcatttgaccttgccagctgaccttcaaaccctgcatttgaaccgaccaacattaagtccagagagtaaacttgaatggaataacgacattccagaagttaatcatttgaattctgaacactggagaaaaaccgaaaaatggacggggcatgaagagactaatcatctggaaaccgatttcagtggcgatggcatgacagagctagagctcgggcccagccccaggctgcagcccattcgcaggcacccgaaagaacttccccagtatggtggtcctggaaaggacatttttgaagatcaactatatcttcctgtgcattccgatggaatttcagttcatcagatgttcaccatggccaccgcagaacaccgaagtaattccagcatagcggggaagatgttgaccaaggtggagaagaatcacgaaaaggagaagtcacagcacctagaaggcagcgcctcctcttcactctcctctgattagatgaaactgttaccttaccctaaacacagtatttctttttaacttttttatttgtaaactaataaaggtaatcacagccaccaacattccaagctaccctgggtacctttgtgcagtagaagctagtgagcatgtgagcaagcggtgtgcacacggagactcatcgttataatttactatctgccaagagtagaaagaaaggctggggatatttgggttggcttggttttgattttttgcttgtttgtttgttttgtactaaaacagtattatcttttgaatatcgtagggacataagtatatacatgttatccaatcaagatggctagaatggtgcctttctgagtgtctaaaacttgacacccctggtaaatctttcaacacacttccactgcctgcgtaatgaagttttgattcatttttaaccactggaatttttcaatgccgtcattttcagttagatgattttgcactttgagattaaaatgccatgtctatttgattagtcttatttttttatttttacaggcttatcagtctcactgttggctgtcattgtgacaaagtcaaataaacccccaaggacgacacacagtatggatcacatattgtttgacattaagcttttgccagaaaatgttgcatgtgttttacctcgacttgctaaaatcgattagcagaaaggcatggctaataatgttggtggtgaaaataaataaataagtaaacaaaatgaagattgcctgctctctctgtgcctagcctcaaagcgttcatcatacatcatacctttaagattgctatattttgggttattttcttgacaggagaaaaagatctaaagatcttttattttcatcttttttggttttcttggcatgactaagaagcttaaatgttgataaaatatgactagttttgaatttacaccaagaacttctcaataaaagaaaatcatgaatgctccacaatttcaacataccacaagagaagttaatttcttaacattgtgttctatgattatttgtaagaccttcaccaagttctgatatcttttaaagacatagttcaaaattgcttttgaaaatctgtattcttgaaaatatccttgttgtgtattaggtttttaaataccagctaaaggattacctcactgagtcatcagtaccctcctattcagctccccaagatgatgtgtttttgcttaccctaagagaggttttcttcttatttttagataattcaagtgcttagataaattatgttttctttaagtgtttatggtaaactcttttaaagaaaatttaatatgttatagctgaatctttttggtaactttaaatctttatcatagactctgtacatatgttcaaattagctgcttgcctgatgtgtgtatcatcggtgggatgacagaacaaacatatttatgatcatgaataatgtgctttgtaaaaagatttcaagttattaggaagcatactctgttttttaatcatgtataatattccatgatacttttatagaacaattctggcttcaggaaagtctagaagcaatatttcttcaaataaaaggtgtttaaacttt
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:23213 -> Molecular function: GO:0004065 [arylsulfatase activity] evidence: IDA
GeneID:23213 -> Molecular function: GO:0004065 [arylsulfatase activity] evidence: IMP
GeneID:23213 -> Molecular function: GO:0005509 [calcium ion binding] evidence: IEA
GeneID:23213 -> Molecular function: GO:0008449 [N-acetylglucosamine-6-sulfatase activity] evidence: IDA
GeneID:23213 -> Molecular function: GO:0008449 [N-acetylglucosamine-6-sulfatase activity] evidence: IMP
GeneID:23213 -> Biological process: GO:0001822 [kidney development] evidence: ISS
GeneID:23213 -> Biological process: GO:0001937 [negative regulation of endothelial cell proliferation] evidence: IDA
GeneID:23213 -> Biological process: GO:0002063 [chondrocyte development] evidence: ISS
GeneID:23213 -> Biological process: GO:0003094 [glomerular filtration] evidence: ISS
GeneID:23213 -> Biological process: GO:0006915 [apoptotic process] evidence: IEA
GeneID:23213 -> Biological process: GO:0010575 [positive regulation vascular endothelial growth factor production] evidence: ISS
GeneID:23213 -> Biological process: GO:0014846 [esophagus smooth muscle contraction] evidence: ISS
GeneID:23213 -> Biological process: GO:0016525 [negative regulation of angiogenesis] evidence: IDA
GeneID:23213 -> Biological process: GO:0030177 [positive regulation of Wnt receptor signaling pathway] evidence: IDA
GeneID:23213 -> Biological process: GO:0030201 [heparan sulfate proteoglycan metabolic process] evidence: IDA
GeneID:23213 -> Biological process: GO:0030201 [heparan sulfate proteoglycan metabolic process] evidence: NAS
GeneID:23213 -> Biological process: GO:0030336 [negative regulation of cell migration] evidence: IMP
GeneID:23213 -> Biological process: GO:0030513 [positive regulation of BMP signaling pathway] evidence: IMP
GeneID:23213 -> Biological process: GO:0032836 [glomerular basement membrane development] evidence: ISS
GeneID:23213 -> Biological process: GO:0035860 [glial cell-derived neurotrophic factor receptor signaling pathway] evidence: ISS
GeneID:23213 -> Biological process: GO:0040036 [regulation of fibroblast growth factor receptor signaling pathway] evidence: IMP
GeneID:23213 -> Biological process: GO:0040037 [negative regulation of fibroblast growth factor receptor signaling pathway] evidence: IMP
GeneID:23213 -> Biological process: GO:0040037 [negative regulation of fibroblast growth factor receptor signaling pathway] evidence: ISS
GeneID:23213 -> Biological process: GO:0048010 [vascular endothelial growth factor receptor signaling pathway] evidence: IDA
GeneID:23213 -> Biological process: GO:0048706 [embryonic skeletal system development] evidence: ISS
GeneID:23213 -> Biological process: GO:0051216 [cartilage development] evidence: ISS
GeneID:23213 -> Biological process: GO:0060348 [bone development] evidence: ISS
GeneID:23213 -> Biological process: GO:0060384 [innervation] evidence: ISS
GeneID:23213 -> Biological process: GO:0060686 [negative regulation of prostatic bud formation] evidence: ISS
GeneID:23213 -> Cellular component: GO:0005615 [extracellular space] evidence: IDA
GeneID:23213 -> Cellular component: GO:0005615 [extracellular space] evidence: NAS
GeneID:23213 -> Cellular component: GO:0005783 [endoplasmic reticulum] evidence: IDA
GeneID:23213 -> Cellular component: GO:0005794 [Golgi apparatus] evidence: ISS
GeneID:23213 -> Cellular component: GO:0005795 [Golgi stack] evidence: IEA
GeneID:23213 -> Cellular component: GO:0005886 [plasma membrane] evidence: ISS
GeneID:23213 -> Cellular component: GO:0009986 [cell surface] evidence: IDA
GeneID:23213 -> Cellular component: GO:0045121 [membrane raft] evidence: IDA
by
@meso_cacase at
DBCLS
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