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2024-04-26 09:13:38, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001127666            2756 bp    mRNA    linear   PRI 16-JUN-2013
DEFINITION  Homo sapiens gelsolin (GSN), transcript variant 7, mRNA.
ACCESSION   NM_001127666
VERSION     NM_001127666.1  GI:189083779
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2756)
  AUTHORS   DiNubile,M.J.
  TITLE     Plasma gelsolin levels in the diagnosis, prognosis, and treatment
            of lung complications of prematurity
  JOURNAL   Am. J. Respir. Crit. Care Med. 186 (11), 1195-1196 (2012)
   PUBMED   23204381
  REMARK    GeneRIF: Circulating gelsolin level is an important biomarker in
            preterm infants, developing bronchopulmonary dysplasia.
REFERENCE   2  (bases 1 to 2756)
  AUTHORS   Li,G.H., Arora,P.D., Chen,Y., McCulloch,C.A. and Liu,P.
  TITLE     Multifunctional roles of gelsolin in health and diseases
  JOURNAL   Med Res Rev 32 (5), 999-1025 (2012)
   PUBMED   22886630
  REMARK    GeneRIF: REVIEW: functions of the plasma and cytoplasmic forms of
            gelsolin, and their manifold impacts on cancer, apoptosis,
            infection and inflammation, cardiac injury, pulmonary diseases, and
            aging
            Review article
REFERENCE   3  (bases 1 to 2756)
  AUTHORS   Shirkoohi,R., Fujita,H., Darmanin,S. and Takimoto,M.
  TITLE     Gelsolin induces promonocytic leukemia differentiation accompanied
            by upregulation of p21CIP1
  JOURNAL   Asian Pac. J. Cancer Prev. 13 (9), 4827-4834 (2012)
   PUBMED   23167427
  REMARK    GeneRIF: Our work confirms that the cytoskeletal tumor suppressor,
            gelsolin, can induce monocytic myeloid differentiation in addition
            to growth retardation in the human monocytic cell line U937.
REFERENCE   4  (bases 1 to 2756)
  AUTHORS   Mazumdar,B., Meyer,K. and Ray,R.
  TITLE     N-terminal region of gelsolin induces apoptosis of activated
            hepatic stellate cells by a caspase-dependent mechanism
  JOURNAL   PLoS ONE 7 (8), E44461 (2012)
   PUBMED   22952982
  REMARK    GeneRIF: Gelsolin modulation of cell death involved upregulation of
            TRAIL-R1 and TRAIL-R2, and involved caspase 3 activation by
            extrinsic pathway.
REFERENCE   5  (bases 1 to 2756)
  AUTHORS   Zhuo,J., Tan,E.H., Yan,B., Tochhawng,L., Jayapal,M., Koh,S.,
            Tay,H.K., Maciver,S.K., Hooi,S.C., Salto-Tellez,M., Kumar,A.P.,
            Goh,Y.C., Lim,Y.C. and Yap,C.T.
  TITLE     Gelsolin induces colorectal tumor cell invasion via modulation of
            the urokinase-type plasminogen activator cascade
  JOURNAL   PLoS ONE 7 (8), E43594 (2012)
   PUBMED   22927998
  REMARK    GeneRIF: novel functions of gelsolin in colorectal tumor cell
            invasion through its modulation of the uPA/uPAR cascade
REFERENCE   6  (bases 1 to 2756)
  AUTHORS   de la Chapelle,A., Tolvanen,R., Boysen,G., Santavy,J.,
            Bleeker-Wagemakers,L., Maury,C.P. and Kere,J.
  TITLE     Gelsolin-derived familial amyloidosis caused by asparagine or
            tyrosine substitution for aspartic acid at residue 187
  JOURNAL   Nat. Genet. 2 (2), 157-160 (1992)
   PUBMED   1338910
REFERENCE   7  (bases 1 to 2756)
  AUTHORS   Yu,F.X., Sun,H.Q., Janmey,P.A. and Yin,H.L.
  TITLE     Identification of a polyphosphoinositide-binding sequence in an
            actin monomer-binding domain of gelsolin
  JOURNAL   J. Biol. Chem. 267 (21), 14616-14621 (1992)
   PUBMED   1321812
REFERENCE   8  (bases 1 to 2756)
  AUTHORS   de la Chapelle,A., Kere,J., Sack,G.H. Jr., Tolvanen,R. and
            Maury,C.P.
  TITLE     Familial amyloidosis, Finnish type: G654----a mutation of the
            gelsolin gene in Finnish families and an unrelated American family
  JOURNAL   Genomics 13 (3), 898-901 (1992)
   PUBMED   1322359
REFERENCE   9  (bases 1 to 2756)
  AUTHORS   Paunio,T., Kiuru,S., Hongell,V., Mustonen,E., Syvanen,A.C.,
            Bengstrom,M., Palo,J. and Peltonen,L.
  TITLE     Solid-phase minisequencing test reveals Asp187----Asn (G654----A)
            mutation of gelsolin in all affected individuals with Finnish type
            of familial amyloidosis
  JOURNAL   Genomics 13 (1), 237-239 (1992)
   PUBMED   1315718
REFERENCE   10 (bases 1 to 2756)
  AUTHORS   Haltia,M., Levy,E., Meretoja,J., Fernandez-Madrid,I., Koivunen,O.
            and Frangione,B.
  TITLE     Gelsolin gene mutation--at codon 187--in familial amyloidosis,
            Finnish: DNA-diagnostic assay
  JOURNAL   Am. J. Med. Genet. 42 (3), 357-359 (1992)
   PUBMED   1311149
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA294394.1, DC341948.1,
            AK096280.1 and BC017491.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: The protein encoded by this gene binds to the 'plus' ends
            of actin monomers and filaments to prevent monomer exchange. The
            encoded calcium-regulated protein functions in both assembly and
            disassembly of actin filaments. Defects in this gene are a cause of
            familial amyloidosis Finnish type (FAF). Multiple transcript
            variants encoding several different isoforms have been found for
            this gene. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (7) differs in the 5' UTR and
            coding sequence compared to variant 1. The resulting isoform (c)
            has a shorter and distinct N-terminus compared to isoform a.
            Variants 7 and 8 both encode isoform c.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK295572.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           ERS025082, ERS025083 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-34                DA294394.1         1-34
            35-608              DC341948.1         1-574
            609-2622            AK096280.1         511-2524
            2623-2756           BC017491.1         996-1129
FEATURES             Location/Qualifiers
     source          1..2756
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q33"
     gene            1..2756
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="gelsolin"
                     /db_xref="GeneID:2934"
                     /db_xref="HGNC:4620"
                     /db_xref="MIM:137350"
     exon            1..118
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     exon            119..211
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       129
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:151083385"
     variation       165
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11550200"
     exon            212..282
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    244..246
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="upstream in-frame stop codon"
     variation       245
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:202184446"
     variation       257
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:369491966"
     CDS             259..2487
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="isoform c is encoded by transcript variant 7;
                     brevin; actin-depolymerizing factor"
                     /codon_start=1
                     /product="gelsolin isoform c"
                     /protein_id="NP_001121138.1"
                     /db_xref="GI:189083780"
                     /db_xref="CCDS:CCDS48011.1"
                     /db_xref="GeneID:2934"
                     /db_xref="HGNC:4620"
                     /db_xref="MIM:137350"
                     /translation="
MEKLFCCFPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVDPLDRAMAELAA
"
     misc_feature    313..651
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="Gelsolin sub-domain 1-like domain found in
                     gelsolin, severin, villin, and related proteins; Region:
                     gelsolin_S1_like; cd11290"
                     /db_xref="CDD:200446"
     misc_feature    order(364..369,484..486,502..507,511..519,523..531,
                     535..540,571..573,577..579)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative actin binding interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:200446"
     misc_feature    order(415..417,508..510)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 2 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200446"
     misc_feature    544..546
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 1 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200446"
     misc_feature    694..963
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="Gelsolin sub-domain 2-like domain found in
                     gelsolin, severin, villin, and related proteins; Region:
                     gelsolin_S2_like; cd11289"
                     /db_xref="CDD:200445"
     misc_feature    order(778..780,844..846)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 2 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200445"
     misc_feature    1021..1323
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="Gelsolin sub-domain 3-like domain found in
                     gelsolin, severin, villin, and related proteins; Region:
                     gelsolin_S3_like; cd11292"
                     /db_xref="CDD:200448"
     misc_feature    order(1126..1128,1198..1200)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 2 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200448"
     misc_feature    order(1306..1308,1321..1323)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative nucleotide binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:200448"
     misc_feature    1453..1755
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="Gelsolin sub-domain 4-like domain found in
                     gelsolin, severin, villin, and related proteins; Region:
                     gelsolin_S4_like; cd11293"
                     /db_xref="CDD:200449"
     misc_feature    order(1501..1506,1618..1620,1636..1641,1645..1653,
                     1657..1665,1669..1674,1705..1707,1711..1713)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative actin binding interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:200449"
     misc_feature    order(1552..1554,1642..1644)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 2 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200449"
     misc_feature    1678..1680
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 1 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200449"
     misc_feature    1726..1728
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative nucleotide binding residue [chemical
                     binding]; other site"
                     /db_xref="CDD:200449"
     misc_feature    1819..2085
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="Gelsolin sub-domain 5-like domain found in
                     gelsolin, severin, villin, and related proteins; Region:
                     gelsolin_S5_like; cd11288"
                     /db_xref="CDD:200444"
     misc_feature    1843..1845
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative nucleotide binding residue [chemical
                     binding]; other site"
                     /db_xref="CDD:200444"
     misc_feature    order(1909..1914,1978..1980)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 2 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200444"
     misc_feature    2134..2430
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="Gelsolin sub-domain 6-like domain found in
                     gelsolin, severin, villin, and related proteins; Region:
                     gelsolin_S6_like; cd11291"
                     /db_xref="CDD:200447"
     misc_feature    order(2227..2229,2293..2295)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 2 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200447"
     variation       267
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:201734352"
     exon            283..487
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       285
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150353588"
     variation       298
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:138068754"
     STS             305..485
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="GSN"
                     /db_xref="UniSTS:253982"
     variation       310
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143781307"
     variation       320
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:115224458"
     STS             345..622
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="MARC_23632-23633:1027531903:1"
                     /db_xref="UniSTS:268728"
     variation       352
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373791435"
     variation       366
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:149415778"
     variation       377
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149556868"
     variation       379
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376961112"
     variation       381
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201642174"
     variation       390
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370368742"
     variation       401
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:144219139"
     variation       408
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374052802"
     variation       417
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200027070"
     variation       418
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:148748121"
     variation       423
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368210196"
     variation       424
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142305374"
     variation       447
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201102347"
     variation       449
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:368868605"
     variation       453
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146365204"
     variation       471
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139689268"
     variation       477
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144551136"
     exon            488..642
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       492
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373229223"
     variation       513
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376627635"
     variation       514
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369305328"
     variation       516
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371165744"
     variation       518
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:79630438"
     variation       522
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:140734150"
     variation       523
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2230287"
     variation       532
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145441439"
     variation       534
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:116956127"
     variation       562
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146956976"
     variation       563
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:138153246"
     variation       576
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142155964"
     variation       578
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201920706"
     variation       594
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373779982"
     variation       613
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367933536"
     exon            643..804
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       672
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:180689280"
     variation       673
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41305623"
     variation       684
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186654124"
     variation       688
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368197143"
     STS             694..803
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="GDB:597556"
                     /db_xref="UniSTS:158100"
     variation       711
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143628574"
     variation       721
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138951454"
     variation       722
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144099356"
     variation       725
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141314418"
     variation       734
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150617780"
     variation       778
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:121909715"
     exon            805..954
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       829
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11550199"
     variation       838
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371175865"
     variation       839
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375589943"
     variation       888
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146329975"
     variation       907
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376060588"
     variation       922
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369788495"
     variation       929
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371320840"
     variation       950
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:374011467"
     exon            955..1044
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       971
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202067009"
     variation       980
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139723535"
     variation       1000
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376744130"
     variation       1012
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:150568054"
     variation       1013
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144375242"
     variation       1014
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377624593"
     variation       1021
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188214536"
     variation       1027
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146112795"
     variation       1043
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148800857"
     exon            1045..1177
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       1045
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113759985"
     variation       1071
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201395524"
     variation       1132
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142435036"
     variation       1146
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374571846"
     variation       1147
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151155909"
     exon            1178..1266
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       1219..1220
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="ac"
                     /replace="c"
                     /db_xref="dbSNP:148582809"
     variation       1238
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139028645"
     exon            1267..1482
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       1272
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145170518"
     variation       1328
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372681751"
     variation       1335
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377247829"
     variation       1338
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367632035"
     variation       1369
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:75508371"
     variation       1373
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370764119"
     variation       1387
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375323203"
     variation       1389
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201325199"
     variation       1392
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371171301"
     variation       1404
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200399610"
     variation       1405
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200018246"
     variation       1435
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376180600"
     variation       1449
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201365952"
     variation       1450
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372218880"
     variation       1461
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147583697"
     variation       1462
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142034230"
     variation       1471
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376488491"
     variation       1481
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368537807"
     exon            1483..1616
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       1491
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371836872"
     variation       1494
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202240818"
     variation       1495
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368079865"
     variation       1512
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111273576"
     variation       1516
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140042418"
     variation       1530
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149375418"
     variation       1544
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375227932"
     variation       1551
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2304393"
     variation       1579
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:116185403"
     variation       1586
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148309276"
     variation       1591
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368923816"
     exon            1617..1707
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       1641
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:141406100"
     variation       1690
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145721476"
     exon            1708..1878
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       1708
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370997492"
     variation       1711
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138341672"
     variation       1712
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142828669"
     variation       1734
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200156774"
     variation       1735
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375902120"
     variation       1756
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:146125870"
     variation       1776
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374982895"
     variation       1778
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139832048"
     variation       1797
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199681748"
     variation       1804
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:58750568"
     variation       1826
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:77681311"
     variation       1829
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148410442"
     variation       1845
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145051977"
     variation       1846
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147554026"
     variation       1854
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140414249"
     exon            1879..2053
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       1885
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:371993530"
     variation       1928
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184844415"
     variation       1931
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376326631"
     variation       1937
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201307081"
     variation       1953
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144259173"
     variation       1954
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151208452"
     variation       1956
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374022157"
     variation       1971
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:73660439"
     variation       1981
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368207411"
     variation       1985
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:76463933"
     variation       1992
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369846947"
     exon            2054..2178
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       2073
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139239940"
     variation       2076
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145066574"
     variation       2077
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141082919"
     variation       2105
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200319453"
     variation       2141
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:9696578"
     variation       2170
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371328761"
     exon            2179..2256
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       2222
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144434647"
     variation       2248
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:186351262"
     variation       2251
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377710586"
     exon            2257..2317
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       2268
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201752493"
     exon            2318..2726
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       2336
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142854368"
     variation       2347
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375881478"
     variation       2348
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143285592"
     variation       2356
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148360076"
     variation       2360
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141510612"
     variation       2373
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368986042"
     variation       2406
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:9102"
     variation       2407
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139420096"
     STS             2418..2574
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="RH17399"
                     /db_xref="UniSTS:34031"
     variation       2514
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371549019"
     variation       2515
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376801564"
     STS             2516..2681
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="G10520"
                     /db_xref="UniSTS:56986"
     STS             2517..2707
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="SHGC-132035"
                     /db_xref="UniSTS:173882"
     STS             2519..2646
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="STS-X04412"
                     /db_xref="UniSTS:16463"
     STS             2532..2692
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="D9S1050E"
                     /db_xref="UniSTS:29132"
     STS             2544..2650
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="D9S1953"
                     /db_xref="UniSTS:63945"
     variation       2549
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1051142"
     variation       2560
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374518331"
     variation       2561
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143181937"
     variation       2575
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1051174"
     variation       2583..2584
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="gtgt"
                     /db_xref="dbSNP:147410423"
     variation       2584..2585
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="gtgt"
                     /db_xref="dbSNP:372955427"
     variation       2604..2605
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="gtgt"
                     /db_xref="dbSNP:71694034"
     variation       2609..2610
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:377469209"
     variation       2609
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:15034"
     variation       2612
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:66991108"
     variation       2615..2616
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="ttt"
                     /db_xref="dbSNP:369363704"
     variation       2615
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:71663525"
     variation       2616..2617
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:376569726"
     variation       2622..2623
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:71680051"
     variation       2624..2625
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="tttt"
                     /db_xref="dbSNP:71659520"
     variation       2627
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:73660440"
     variation       2629
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:11550202"
     variation       2655..2656
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="ag"
                     /db_xref="dbSNP:71695753"
     variation       2674
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1051286"
ORIGIN      
tcccgcccgcgccctgcccaccccggccgcgcgcaccacaacgcccccgccccgccgcccggaaccagctgagcgcagctggacccagcagccgctgtctccagtgccgcagcagcaggtagtgctcatagctctctttgtccagtgcttcggccttggtcccagcgccttcccacggagcagcactcttcaccctgcacagccttgttagttcttgcagatacagcgctaggaaaaggggagtaattcaggtctagaatggaaaaactgttttgttgctttcccaacagcatggtggtggaacaccccgagttcctcaaggcagggaaggagcctggcctgcagatctggcgtgtggagaagttcgatctggtgcccgtgcccaccaacctttatggagacttcttcacgggcgacgcctacgtcatcctgaagacagtgcagctgaggaacggaaatctgcagtatgacctccactactggctgggcaatgagtgcagccaggatgagagcggggcggccgccatctttaccgtgcagctggatgactacctgaacggccgggccgtgcagcaccgtgaggtccagggcttcgagtcggccaccttcctaggctacttcaagtctggcctgaagtacaagaaaggaggtgtggcatcaggattcaagcacgtggtacccaacgaggtggtggtgcagagactcttccaggtcaaagggcggcgtgtggtccgtgccaccgaggtacctgtgtcctgggagagcttcaacaatggcgactgcttcatcctggacctgggcaacaacatccaccagtggtgtggttccaacagcaatcggtatgaaagactgaaggccacacaggtgtccaagggcatccgggacaacgagcggagtggccgggcccgagtgcacgtgtctgaggagggcactgagcccgaggcgatgctccaggtgctgggccccaagccggctctgcctgcaggtaccgaggacaccgccaaggaggatgcggccaaccgcaagctggccaagctctacaaggtctccaatggtgcagggaccatgtccgtctccctcgtggctgatgagaaccccttcgcccagggggccctgaagtcagaggactgcttcatcctggaccacggcaaagatgggaaaatctttgtctggaaaggcaagcaggcaaacacggaggagaggaaggctgccctcaaaacagcctctgacttcatcaccaagatggactaccccaagcagactcaggtctcggtccttcctgagggcggtgagaccccactgttcaagcagttcttcaagaactggcgggacccagaccagacagatggcctgggcttgtcctacctttccagccatatcgccaacgtggagcgggtgcccttcgacgccgccaccctgcacacctccactgccatggccgcccagcacggcatggatgacgatggcacaggccagaaacagatctggagaatcgaaggttccaacaaggtgcccgtggaccctgccacatatggacagttctatggaggcgacagctacatcattctgtacaactaccgccatggtggccgccaggggcagataatctataactggcagggtgcccagtctacccaggatgaggtcgctgcatctgccatcctgactgctcagctggatgaggagctgggaggtacccctgtccagagccgtgtggtccaaggcaaggagcccgcccacctcatgagcctgtttggtgggaagcccatgatcatctacaagggcggcacctcccgcgagggcgggcagacagcccctgccagcacccgcctcttccaggtccgcgccaacagcgctggagccacccgggctgttgaggtattgcctaaggctggtgcactgaactccaacgatgcctttgttctgaaaaccccctcagccgcctacctgtgggtgggtacaggagccagcgaggcagagaagacgggggcccaggagctgctcagggtgctgcgggcccaacctgtgcaggtggcagaaggcagcgagccagatggcttctgggaggccctgggcgggaaggctgcctaccgcacatccccacggctgaaggacaagaagatggatgcccatcctcctcgcctctttgcctgctccaacaagattggacgttttgtgatcgaagaggttcctggtgagctcatgcaggaagacctggcaacggatgacgtcatgcttctggacacctgggaccaggtctttgtctgggttggaaaggattctcaagaagaagaaaagacagaagccttgacttctgctaagcggtacatcgagacggacccagccaatcgggatcggcggacgcccatcaccgtggtgaagcaaggctttgagcctccctcctttgtgggctggttccttggctgggatgatgattactggtctgtggaccccttggacagggccatggctgagctggctgcctgaggaggggcagggcccacccatgtcaccggtcagtgccttttggaactgtccttccctcaaagaggccttagagcgagcagagcagctctgctatgagtgtgtgtgtgtgtgtgtgttgtttcttttttttttttttacagtatccaaaaatagccctgcaaaaattcagagtccttgcaaaattgtctaaaatgtcagtgtttgggaaattaaatccaataaaaacattttgaagtgtgaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:2934 -> Molecular function: GO:0003779 [actin binding] evidence: IEA
            GeneID:2934 -> Molecular function: GO:0005509 [calcium ion binding] evidence: TAS
            GeneID:2934 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:2934 -> Biological process: GO:0006915 [apoptotic process] evidence: TAS
            GeneID:2934 -> Biological process: GO:0006921 [cellular component disassembly involved in execution phase of apoptosis] evidence: TAS
            GeneID:2934 -> Biological process: GO:0007568 [aging] evidence: IEA
            GeneID:2934 -> Biological process: GO:0014003 [oligodendrocyte development] evidence: IEA
            GeneID:2934 -> Biological process: GO:0016192 [vesicle-mediated transport] evidence: IEA
            GeneID:2934 -> Biological process: GO:0030041 [actin filament polymerization] evidence: IDA
            GeneID:2934 -> Biological process: GO:0030041 [actin filament polymerization] evidence: ISS
            GeneID:2934 -> Biological process: GO:0030155 [regulation of cell adhesion] evidence: IEA
            GeneID:2934 -> Biological process: GO:0042246 [tissue regeneration] evidence: IEA
            GeneID:2934 -> Biological process: GO:0045471 [response to ethanol] evidence: IEA
            GeneID:2934 -> Biological process: GO:0048015 [phosphatidylinositol-mediated signaling] evidence: IEA
            GeneID:2934 -> Biological process: GO:0051014 [actin filament severing] evidence: IDA
            GeneID:2934 -> Biological process: GO:0051014 [actin filament severing] evidence: ISS
            GeneID:2934 -> Biological process: GO:0051016 [barbed-end actin filament capping] evidence: TAS
            GeneID:2934 -> Biological process: GO:0051593 [response to folic acid] evidence: IEA
            GeneID:2934 -> Biological process: GO:0060271 [cilium morphogenesis] evidence: IMP
            GeneID:2934 -> Biological process: GO:0071276 [cellular response to cadmium ion] evidence: IEA
            GeneID:2934 -> Cellular component: GO:0001726 [ruffle] evidence: IEA
            GeneID:2934 -> Cellular component: GO:0005576 [extracellular region] evidence: IDA
            GeneID:2934 -> Cellular component: GO:0005576 [extracellular region] evidence: ISS
            GeneID:2934 -> Cellular component: GO:0005576 [extracellular region] evidence: NAS
            GeneID:2934 -> Cellular component: GO:0005576 [extracellular region] evidence: TAS
            GeneID:2934 -> Cellular component: GO:0005615 [extracellular space] evidence: IEA
            GeneID:2934 -> Cellular component: GO:0005829 [cytosol] evidence: IDA
            GeneID:2934 -> Cellular component: GO:0005829 [cytosol] evidence: ISS
            GeneID:2934 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:2934 -> Cellular component: GO:0015629 [actin cytoskeleton] evidence: IEA
            GeneID:2934 -> Cellular component: GO:0030027 [lamellipodium] evidence: IEA
            GeneID:2934 -> Cellular component: GO:0043234 [protein complex] evidence: IEA
            GeneID:2934 -> Cellular component: GO:0048471 [perinuclear region of cytoplasm] evidence: IEA
            GeneID:2934 -> Cellular component: GO:0070062 [extracellular vesicular exosome] evidence: IDA

by @meso_cacase at DBCLS
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