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2024-04-25 07:40:18, GGRNA : RefSeq release 60 (20130726)

LOCUS       NM_001127664            2764 bp    mRNA    linear   PRI 16-JUN-2013
DEFINITION  Homo sapiens gelsolin (GSN), transcript variant 5, mRNA.
ACCESSION   NM_001127664
VERSION     NM_001127664.1  GI:189083775
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2764)
  AUTHORS   DiNubile,M.J.
  TITLE     Plasma gelsolin levels in the diagnosis, prognosis, and treatment
            of lung complications of prematurity
  JOURNAL   Am. J. Respir. Crit. Care Med. 186 (11), 1195-1196 (2012)
   PUBMED   23204381
  REMARK    GeneRIF: Circulating gelsolin level is an important biomarker in
            preterm infants, developing bronchopulmonary dysplasia.
REFERENCE   2  (bases 1 to 2764)
  AUTHORS   Li,G.H., Arora,P.D., Chen,Y., McCulloch,C.A. and Liu,P.
  TITLE     Multifunctional roles of gelsolin in health and diseases
  JOURNAL   Med Res Rev 32 (5), 999-1025 (2012)
   PUBMED   22886630
  REMARK    GeneRIF: REVIEW: functions of the plasma and cytoplasmic forms of
            gelsolin, and their manifold impacts on cancer, apoptosis,
            infection and inflammation, cardiac injury, pulmonary diseases, and
            aging
            Review article
REFERENCE   3  (bases 1 to 2764)
  AUTHORS   Shirkoohi,R., Fujita,H., Darmanin,S. and Takimoto,M.
  TITLE     Gelsolin induces promonocytic leukemia differentiation accompanied
            by upregulation of p21CIP1
  JOURNAL   Asian Pac. J. Cancer Prev. 13 (9), 4827-4834 (2012)
   PUBMED   23167427
  REMARK    GeneRIF: Our work confirms that the cytoskeletal tumor suppressor,
            gelsolin, can induce monocytic myeloid differentiation in addition
            to growth retardation in the human monocytic cell line U937.
REFERENCE   4  (bases 1 to 2764)
  AUTHORS   Mazumdar,B., Meyer,K. and Ray,R.
  TITLE     N-terminal region of gelsolin induces apoptosis of activated
            hepatic stellate cells by a caspase-dependent mechanism
  JOURNAL   PLoS ONE 7 (8), E44461 (2012)
   PUBMED   22952982
  REMARK    GeneRIF: Gelsolin modulation of cell death involved upregulation of
            TRAIL-R1 and TRAIL-R2, and involved caspase 3 activation by
            extrinsic pathway.
REFERENCE   5  (bases 1 to 2764)
  AUTHORS   Zhuo,J., Tan,E.H., Yan,B., Tochhawng,L., Jayapal,M., Koh,S.,
            Tay,H.K., Maciver,S.K., Hooi,S.C., Salto-Tellez,M., Kumar,A.P.,
            Goh,Y.C., Lim,Y.C. and Yap,C.T.
  TITLE     Gelsolin induces colorectal tumor cell invasion via modulation of
            the urokinase-type plasminogen activator cascade
  JOURNAL   PLoS ONE 7 (8), E43594 (2012)
   PUBMED   22927998
  REMARK    GeneRIF: novel functions of gelsolin in colorectal tumor cell
            invasion through its modulation of the uPA/uPAR cascade
REFERENCE   6  (bases 1 to 2764)
  AUTHORS   de la Chapelle,A., Tolvanen,R., Boysen,G., Santavy,J.,
            Bleeker-Wagemakers,L., Maury,C.P. and Kere,J.
  TITLE     Gelsolin-derived familial amyloidosis caused by asparagine or
            tyrosine substitution for aspartic acid at residue 187
  JOURNAL   Nat. Genet. 2 (2), 157-160 (1992)
   PUBMED   1338910
REFERENCE   7  (bases 1 to 2764)
  AUTHORS   Yu,F.X., Sun,H.Q., Janmey,P.A. and Yin,H.L.
  TITLE     Identification of a polyphosphoinositide-binding sequence in an
            actin monomer-binding domain of gelsolin
  JOURNAL   J. Biol. Chem. 267 (21), 14616-14621 (1992)
   PUBMED   1321812
REFERENCE   8  (bases 1 to 2764)
  AUTHORS   de la Chapelle,A., Kere,J., Sack,G.H. Jr., Tolvanen,R. and
            Maury,C.P.
  TITLE     Familial amyloidosis, Finnish type: G654----a mutation of the
            gelsolin gene in Finnish families and an unrelated American family
  JOURNAL   Genomics 13 (3), 898-901 (1992)
   PUBMED   1322359
REFERENCE   9  (bases 1 to 2764)
  AUTHORS   Paunio,T., Kiuru,S., Hongell,V., Mustonen,E., Syvanen,A.C.,
            Bengstrom,M., Palo,J. and Peltonen,L.
  TITLE     Solid-phase minisequencing test reveals Asp187----Asn (G654----A)
            mutation of gelsolin in all affected individuals with Finnish type
            of familial amyloidosis
  JOURNAL   Genomics 13 (1), 237-239 (1992)
   PUBMED   1315718
REFERENCE   10 (bases 1 to 2764)
  AUTHORS   Haltia,M., Levy,E., Meretoja,J., Fernandez-Madrid,I., Koivunen,O.
            and Frangione,B.
  TITLE     Gelsolin gene mutation--at codon 187--in familial amyloidosis,
            Finnish: DNA-diagnostic assay
  JOURNAL   Am. J. Med. Genet. 42 (3), 357-359 (1992)
   PUBMED   1311149
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DA294394.1, DB170452.1,
            AK096280.1 and BC017491.1.
            
            Summary: The protein encoded by this gene binds to the 'plus' ends
            of actin monomers and filaments to prevent monomer exchange. The
            encoded calcium-regulated protein functions in both assembly and
            disassembly of actin filaments. Defects in this gene are a cause of
            familial amyloidosis Finnish type (FAF). Multiple transcript
            variants encoding several different isoforms have been found for
            this gene. [provided by RefSeq, Jul 2008].
            
            Transcript Variant: This variant (5) differs in the 5' UTR and
            coding sequence compared to variant 1. The resulting isoform (b)
            has a shorter N-terminus compared to isoform a. Variants 2, 3, 5,
            and 6 all encode isoform b.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: BX647999.1, AK304675.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    ERS025084, ERS025088 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-62                DA294394.1         1-62
            63-530              DB170452.1         1-468
            531-2630            AK096280.1         425-2524
            2631-2764           BC017491.1         996-1129
FEATURES             Location/Qualifiers
     source          1..2764
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q33"
     gene            1..2764
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="gelsolin"
                     /db_xref="GeneID:2934"
                     /db_xref="HGNC:4620"
                     /db_xref="MIM:137350"
     exon            1..118
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     exon            119..211
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       129
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:151083385"
     variation       165
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:11550200"
     STS             195..522
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="STS-AA029453"
                     /db_xref="UniSTS:34699"
     exon            212..290
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     misc_feature    249..251
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="upstream in-frame stop codon"
     exon            291..495
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       293
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150353588"
     CDS             300..2495
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="isoform b is encoded by transcript variant 5;
                     brevin; actin-depolymerizing factor"
                     /codon_start=1
                     /product="gelsolin isoform b"
                     /protein_id="NP_001121136.1"
                     /db_xref="GI:189083776"
                     /db_xref="CCDS:CCDS6829.1"
                     /db_xref="GeneID:2934"
                     /db_xref="HGNC:4620"
                     /db_xref="MIM:137350"
                     /translation="
MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVDPLDRAMAELAA
"
     misc_feature    321..659
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="Gelsolin sub-domain 1-like domain found in
                     gelsolin, severin, villin, and related proteins; Region:
                     gelsolin_S1_like; cd11290"
                     /db_xref="CDD:200446"
     misc_feature    order(372..377,492..494,510..515,519..527,531..539,
                     543..548,579..581,585..587)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative actin binding interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:200446"
     misc_feature    order(423..425,516..518)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 2 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200446"
     misc_feature    552..554
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 1 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200446"
     misc_feature    702..971
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="Gelsolin sub-domain 2-like domain found in
                     gelsolin, severin, villin, and related proteins; Region:
                     gelsolin_S2_like; cd11289"
                     /db_xref="CDD:200445"
     misc_feature    order(786..788,852..854)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 2 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200445"
     misc_feature    1029..1331
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="Gelsolin sub-domain 3-like domain found in
                     gelsolin, severin, villin, and related proteins; Region:
                     gelsolin_S3_like; cd11292"
                     /db_xref="CDD:200448"
     misc_feature    order(1134..1136,1206..1208)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 2 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200448"
     misc_feature    order(1314..1316,1329..1331)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative nucleotide binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:200448"
     misc_feature    1461..1763
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="Gelsolin sub-domain 4-like domain found in
                     gelsolin, severin, villin, and related proteins; Region:
                     gelsolin_S4_like; cd11293"
                     /db_xref="CDD:200449"
     misc_feature    order(1509..1514,1626..1628,1644..1649,1653..1661,
                     1665..1673,1677..1682,1713..1715,1719..1721)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative actin binding interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:200449"
     misc_feature    order(1560..1562,1650..1652)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 2 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200449"
     misc_feature    1686..1688
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 1 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200449"
     misc_feature    1734..1736
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative nucleotide binding residue [chemical
                     binding]; other site"
                     /db_xref="CDD:200449"
     misc_feature    1827..2093
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="Gelsolin sub-domain 5-like domain found in
                     gelsolin, severin, villin, and related proteins; Region:
                     gelsolin_S5_like; cd11288"
                     /db_xref="CDD:200444"
     misc_feature    1851..1853
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative nucleotide binding residue [chemical
                     binding]; other site"
                     /db_xref="CDD:200444"
     misc_feature    order(1917..1922,1986..1988)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 2 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200444"
     misc_feature    2142..2438
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="Gelsolin sub-domain 6-like domain found in
                     gelsolin, severin, villin, and related proteins; Region:
                     gelsolin_S6_like; cd11291"
                     /db_xref="CDD:200447"
     misc_feature    order(2235..2237,2301..2303)
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /note="putative type 2 Ca binding site [ion binding];
                     other site"
                     /db_xref="CDD:200447"
     variation       306
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:138068754"
     STS             313..493
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="GSN"
                     /db_xref="UniSTS:253982"
     variation       318
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143781307"
     variation       328
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:115224458"
     STS             353..630
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="MARC_23632-23633:1027531903:1"
                     /db_xref="UniSTS:268728"
     variation       360
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373791435"
     variation       374
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:149415778"
     variation       385
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149556868"
     variation       387
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376961112"
     variation       389
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201642174"
     variation       398
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370368742"
     variation       409
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:144219139"
     variation       416
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374052802"
     variation       425
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200027070"
     variation       426
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:148748121"
     variation       431
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368210196"
     variation       432
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142305374"
     variation       455
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201102347"
     variation       457
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:368868605"
     variation       461
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146365204"
     variation       479
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139689268"
     variation       485
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144551136"
     exon            496..650
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       500
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373229223"
     variation       521
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376627635"
     variation       522
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:369305328"
     variation       524
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371165744"
     variation       526
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:79630438"
     variation       530
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:140734150"
     variation       531
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2230287"
     variation       540
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145441439"
     variation       542
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:116956127"
     variation       570
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146956976"
     variation       571
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:138153246"
     variation       584
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142155964"
     variation       586
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201920706"
     variation       602
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373779982"
     variation       621
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367933536"
     exon            651..812
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       680
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:180689280"
     variation       681
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41305623"
     variation       692
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186654124"
     variation       696
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368197143"
     STS             702..811
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="GDB:597556"
                     /db_xref="UniSTS:158100"
     variation       719
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143628574"
     variation       729
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138951454"
     variation       730
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144099356"
     variation       733
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141314418"
     variation       742
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:150617780"
     variation       786
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:121909715"
     exon            813..962
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       837
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:11550199"
     variation       846
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371175865"
     variation       847
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375589943"
     variation       896
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146329975"
     variation       915
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376060588"
     variation       930
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369788495"
     variation       937
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371320840"
     variation       958
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:374011467"
     exon            963..1052
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       979
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202067009"
     variation       988
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139723535"
     variation       1008
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376744130"
     variation       1020
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:150568054"
     variation       1021
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144375242"
     variation       1022
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377624593"
     variation       1029
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:188214536"
     variation       1035
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146112795"
     variation       1051
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148800857"
     exon            1053..1185
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       1053
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113759985"
     variation       1079
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201395524"
     variation       1140
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142435036"
     variation       1154
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374571846"
     variation       1155
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151155909"
     exon            1186..1274
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       1227..1228
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="ac"
                     /replace="c"
                     /db_xref="dbSNP:148582809"
     variation       1246
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:139028645"
     exon            1275..1490
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       1280
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:145170518"
     variation       1336
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372681751"
     variation       1343
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:377247829"
     variation       1346
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367632035"
     variation       1377
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:75508371"
     variation       1381
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370764119"
     variation       1395
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375323203"
     variation       1397
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201325199"
     variation       1400
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371171301"
     variation       1412
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200399610"
     variation       1413
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200018246"
     variation       1443
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376180600"
     variation       1457
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201365952"
     variation       1458
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:372218880"
     variation       1469
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:147583697"
     variation       1470
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142034230"
     variation       1479
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376488491"
     variation       1489
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368537807"
     exon            1491..1624
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       1499
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371836872"
     variation       1502
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:202240818"
     variation       1503
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368079865"
     variation       1520
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111273576"
     variation       1524
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:140042418"
     variation       1538
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:149375418"
     variation       1552
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375227932"
     variation       1559
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2304393"
     variation       1587
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:116185403"
     variation       1594
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148309276"
     variation       1599
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368923816"
     exon            1625..1715
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       1649
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:141406100"
     variation       1698
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145721476"
     exon            1716..1886
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       1716
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:370997492"
     variation       1719
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:138341672"
     variation       1720
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:142828669"
     variation       1742
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200156774"
     variation       1743
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375902120"
     variation       1764
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:146125870"
     variation       1784
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374982895"
     variation       1786
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139832048"
     variation       1805
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:199681748"
     variation       1812
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:58750568"
     variation       1834
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:77681311"
     variation       1837
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148410442"
     variation       1853
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145051977"
     variation       1854
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147554026"
     variation       1862
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:140414249"
     exon            1887..2061
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       1893
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:371993530"
     variation       1936
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184844415"
     variation       1939
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376326631"
     variation       1945
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201307081"
     variation       1961
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:144259173"
     variation       1962
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:151208452"
     variation       1964
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374022157"
     variation       1979
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:73660439"
     variation       1989
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:368207411"
     variation       1993
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:76463933"
     variation       2000
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369846947"
     exon            2062..2186
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       2081
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139239940"
     variation       2084
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145066574"
     variation       2085
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141082919"
     variation       2113
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200319453"
     variation       2149
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:9696578"
     variation       2178
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371328761"
     exon            2187..2264
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       2230
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144434647"
     variation       2256
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:186351262"
     variation       2259
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:377710586"
     exon            2265..2325
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       2276
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201752493"
     exon            2326..2734
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /inference="alignment:Splign:1.39.8"
     variation       2344
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:142854368"
     variation       2355
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:375881478"
     variation       2356
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:143285592"
     variation       2364
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:148360076"
     variation       2368
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141510612"
     variation       2381
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:368986042"
     variation       2414
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:9102"
     variation       2415
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:139420096"
     STS             2426..2582
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="RH17399"
                     /db_xref="UniSTS:34031"
     variation       2522
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:371549019"
     variation       2523
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:376801564"
     STS             2524..2689
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="G10520"
                     /db_xref="UniSTS:56986"
     STS             2525..2715
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="SHGC-132035"
                     /db_xref="UniSTS:173882"
     STS             2527..2654
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="STS-X04412"
                     /db_xref="UniSTS:16463"
     STS             2540..2700
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="D9S1050E"
                     /db_xref="UniSTS:29132"
     STS             2552..2658
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /standard_name="D9S1953"
                     /db_xref="UniSTS:63945"
     variation       2557
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1051142"
     variation       2568
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:374518331"
     variation       2569
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:143181937"
     variation       2583
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1051174"
     variation       2591..2592
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="gtgt"
                     /db_xref="dbSNP:147410423"
     variation       2592..2593
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="gtgt"
                     /db_xref="dbSNP:372955427"
     variation       2612..2613
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="gtgt"
                     /db_xref="dbSNP:71694034"
     variation       2617..2618
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:377469209"
     variation       2617
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:15034"
     variation       2620
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:66991108"
     variation       2623..2624
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="ttt"
                     /db_xref="dbSNP:369363704"
     variation       2623
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:71663525"
     variation       2624..2625
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:376569726"
     variation       2630..2631
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:71680051"
     variation       2632..2633
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="tttt"
                     /db_xref="dbSNP:71659520"
     variation       2635
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:73660440"
     variation       2637
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:11550202"
     variation       2663..2664
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace=""
                     /replace="ag"
                     /db_xref="dbSNP:71695753"
     variation       2682
                     /gene="GSN"
                     /gene_synonym="ADF; AGEL"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1051286"
ORIGIN      
tcccgcccgcgccctgcccaccccggccgcgcgcaccacaacgcccccgccccgccgcccggaaccagctgagcgcagctggacccagcagccgctgtctccagtgccgcagcagcaggtagtgctcatagctctctttgtccagtgcttcggccttggtcccagcgccttcccacggagcagcactcttcaccctgcacagccttgttaggccttggttgctattctgtagaagagcagagtccccataaagaggaggtgcaggaattcttcccagaggctttggagagcccaacagcatggtggtggaacaccccgagttcctcaaggcagggaaggagcctggcctgcagatctggcgtgtggagaagttcgatctggtgcccgtgcccaccaacctttatggagacttcttcacgggcgacgcctacgtcatcctgaagacagtgcagctgaggaacggaaatctgcagtatgacctccactactggctgggcaatgagtgcagccaggatgagagcggggcggccgccatctttaccgtgcagctggatgactacctgaacggccgggccgtgcagcaccgtgaggtccagggcttcgagtcggccaccttcctaggctacttcaagtctggcctgaagtacaagaaaggaggtgtggcatcaggattcaagcacgtggtacccaacgaggtggtggtgcagagactcttccaggtcaaagggcggcgtgtggtccgtgccaccgaggtacctgtgtcctgggagagcttcaacaatggcgactgcttcatcctggacctgggcaacaacatccaccagtggtgtggttccaacagcaatcggtatgaaagactgaaggccacacaggtgtccaagggcatccgggacaacgagcggagtggccgggcccgagtgcacgtgtctgaggagggcactgagcccgaggcgatgctccaggtgctgggccccaagccggctctgcctgcaggtaccgaggacaccgccaaggaggatgcggccaaccgcaagctggccaagctctacaaggtctccaatggtgcagggaccatgtccgtctccctcgtggctgatgagaaccccttcgcccagggggccctgaagtcagaggactgcttcatcctggaccacggcaaagatgggaaaatctttgtctggaaaggcaagcaggcaaacacggaggagaggaaggctgccctcaaaacagcctctgacttcatcaccaagatggactaccccaagcagactcaggtctcggtccttcctgagggcggtgagaccccactgttcaagcagttcttcaagaactggcgggacccagaccagacagatggcctgggcttgtcctacctttccagccatatcgccaacgtggagcgggtgcccttcgacgccgccaccctgcacacctccactgccatggccgcccagcacggcatggatgacgatggcacaggccagaaacagatctggagaatcgaaggttccaacaaggtgcccgtggaccctgccacatatggacagttctatggaggcgacagctacatcattctgtacaactaccgccatggtggccgccaggggcagataatctataactggcagggtgcccagtctacccaggatgaggtcgctgcatctgccatcctgactgctcagctggatgaggagctgggaggtacccctgtccagagccgtgtggtccaaggcaaggagcccgcccacctcatgagcctgtttggtgggaagcccatgatcatctacaagggcggcacctcccgcgagggcgggcagacagcccctgccagcacccgcctcttccaggtccgcgccaacagcgctggagccacccgggctgttgaggtattgcctaaggctggtgcactgaactccaacgatgcctttgttctgaaaaccccctcagccgcctacctgtgggtgggtacaggagccagcgaggcagagaagacgggggcccaggagctgctcagggtgctgcgggcccaacctgtgcaggtggcagaaggcagcgagccagatggcttctgggaggccctgggcgggaaggctgcctaccgcacatccccacggctgaaggacaagaagatggatgcccatcctcctcgcctctttgcctgctccaacaagattggacgttttgtgatcgaagaggttcctggtgagctcatgcaggaagacctggcaacggatgacgtcatgcttctggacacctgggaccaggtctttgtctgggttggaaaggattctcaagaagaagaaaagacagaagccttgacttctgctaagcggtacatcgagacggacccagccaatcgggatcggcggacgcccatcaccgtggtgaagcaaggctttgagcctccctcctttgtgggctggttccttggctgggatgatgattactggtctgtggaccccttggacagggccatggctgagctggctgcctgaggaggggcagggcccacccatgtcaccggtcagtgccttttggaactgtccttccctcaaagaggccttagagcgagcagagcagctctgctatgagtgtgtgtgtgtgtgtgtgttgtttcttttttttttttttacagtatccaaaaatagccctgcaaaaattcagagtccttgcaaaattgtctaaaatgtcagtgtttgggaaattaaatccaataaaaacattttgaagtgtgaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//

Annotations:

ANNOTATIONS from NCBI Entrez Gene (20130726):
            GeneID:2934 -> Molecular function: GO:0003779 [actin binding] evidence: IEA
            GeneID:2934 -> Molecular function: GO:0005509 [calcium ion binding] evidence: TAS
            GeneID:2934 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
            GeneID:2934 -> Biological process: GO:0006915 [apoptotic process] evidence: TAS
            GeneID:2934 -> Biological process: GO:0006921 [cellular component disassembly involved in execution phase of apoptosis] evidence: TAS
            GeneID:2934 -> Biological process: GO:0007568 [aging] evidence: IEA
            GeneID:2934 -> Biological process: GO:0014003 [oligodendrocyte development] evidence: IEA
            GeneID:2934 -> Biological process: GO:0016192 [vesicle-mediated transport] evidence: IEA
            GeneID:2934 -> Biological process: GO:0030041 [actin filament polymerization] evidence: IDA
            GeneID:2934 -> Biological process: GO:0030041 [actin filament polymerization] evidence: ISS
            GeneID:2934 -> Biological process: GO:0030155 [regulation of cell adhesion] evidence: IEA
            GeneID:2934 -> Biological process: GO:0042246 [tissue regeneration] evidence: IEA
            GeneID:2934 -> Biological process: GO:0045471 [response to ethanol] evidence: IEA
            GeneID:2934 -> Biological process: GO:0048015 [phosphatidylinositol-mediated signaling] evidence: IEA
            GeneID:2934 -> Biological process: GO:0051014 [actin filament severing] evidence: IDA
            GeneID:2934 -> Biological process: GO:0051014 [actin filament severing] evidence: ISS
            GeneID:2934 -> Biological process: GO:0051016 [barbed-end actin filament capping] evidence: TAS
            GeneID:2934 -> Biological process: GO:0051593 [response to folic acid] evidence: IEA
            GeneID:2934 -> Biological process: GO:0060271 [cilium morphogenesis] evidence: IMP
            GeneID:2934 -> Biological process: GO:0071276 [cellular response to cadmium ion] evidence: IEA
            GeneID:2934 -> Cellular component: GO:0001726 [ruffle] evidence: IEA
            GeneID:2934 -> Cellular component: GO:0005576 [extracellular region] evidence: IDA
            GeneID:2934 -> Cellular component: GO:0005576 [extracellular region] evidence: ISS
            GeneID:2934 -> Cellular component: GO:0005576 [extracellular region] evidence: NAS
            GeneID:2934 -> Cellular component: GO:0005576 [extracellular region] evidence: TAS
            GeneID:2934 -> Cellular component: GO:0005615 [extracellular space] evidence: IEA
            GeneID:2934 -> Cellular component: GO:0005829 [cytosol] evidence: IDA
            GeneID:2934 -> Cellular component: GO:0005829 [cytosol] evidence: ISS
            GeneID:2934 -> Cellular component: GO:0005829 [cytosol] evidence: TAS
            GeneID:2934 -> Cellular component: GO:0015629 [actin cytoskeleton] evidence: IEA
            GeneID:2934 -> Cellular component: GO:0030027 [lamellipodium] evidence: IEA
            GeneID:2934 -> Cellular component: GO:0043234 [protein complex] evidence: IEA
            GeneID:2934 -> Cellular component: GO:0048471 [perinuclear region of cytoplasm] evidence: IEA
            GeneID:2934 -> Cellular component: GO:0070062 [extracellular vesicular exosome] evidence: IDA

by @meso_cacase at DBCLS
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