2024-03-28 23:07:58, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001126242 4982 bp mRNA linear PRI 08-JUL-2013 DEFINITION Homo sapiens tumor protein p73 (TP73), transcript variant 4, mRNA. ACCESSION NM_001126242 VERSION NM_001126242.2 GI:323668324 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 4982) AUTHORS Zhang,J., Xu,E. and Chen,X. TITLE TAp73 protein stability is controlled by histone deacetylase 1 via regulation of Hsp90 chaperone function JOURNAL J. Biol. Chem. 288 (11), 7727-7737 (2013) PUBMED 23362263 REMARK GeneRIF: TAp73 protein stability is controlled by histone deacetylase 1 via regulation of Hsp90 chaperone function REFERENCE 2 (bases 1 to 4982) AUTHORS Wang,Y., Radhakrishnan,D., He,X., Peehl,D.M. and Eng,C. TITLE Transcription factor KLLN inhibits tumor growth by AR suppression, induces apoptosis by TP53/TP73 stimulation in prostate carcinomas, and correlates with cellular differentiation JOURNAL J. Clin. Endocrinol. Metab. 98 (3), E586-E594 (2013) PUBMED 23386643 REMARK GeneRIF: KLLN is a transcription factor directly regulating AR, TP53, and TP73 expression, with a role in prostate carcinogenesis. REFERENCE 3 (bases 1 to 4982) AUTHORS Jacobs,D.I., Hansen,J., Fu,A., Stevens,R.G., Tjonneland,A., Vogel,U.B., Zheng,T. and Zhu,Y. TITLE Methylation alterations at imprinted genes detected among long-term shiftworkers JOURNAL Environ. Mol. Mutagen. 54 (2), 141-146 (2013) PUBMED 23193016 REMARK GeneRIF: The strongest evidence for altered methylation patterns in shiftworkers was observed for TP73 gene. REFERENCE 4 (bases 1 to 4982) AUTHORS Ethayathulla,A.S., Nguyen,H.T. and Viadiu,H. TITLE Crystal structures of the DNA-binding domain tetramer of the p53 tumor suppressor family member p73 bound to different full-site response elements JOURNAL J. Biol. Chem. 288 (7), 4744-4754 (2013) PUBMED 23243311 REMARK GeneRIF: Crystal structures of the DNA-binding domain tetramer of the p53 tumor suppressor family member p73 bound to different full-site response elements REFERENCE 5 (bases 1 to 4982) AUTHORS Di,C.X., Yang,L.N., Zhang,H., An,L.Z., Zhang,X., Ma,X.F., Sun,C., Wang,X.H., Yang,R., Wu,Z.H. and Si,J. TITLE Effects of carbon-ion beam or X-ray irradiation on anti-apoptosis DeltaNp73 expression in HeLa cells JOURNAL Gene 515 (1), 208-213 (2013) PUBMED 23228853 REMARK GeneRIF: there is a differential DeltaNp73 expression in response to different LET radiations, and down-regulated DeltaNp73 expression might play a critical role in promoting cycle arrest and apoptosis in cancer cells. REFERENCE 6 (bases 1 to 4982) AUTHORS Mai,M., Qian,C., Yokomizo,A., Tindall,D.J., Bostwick,D., Polychronakos,C., Smith,D.I. and Liu,W. TITLE Loss of imprinting and allele switching of p73 in renal cell carcinoma JOURNAL Oncogene 17 (13), 1739-1741 (1998) PUBMED 9796703 REFERENCE 7 (bases 1 to 4982) AUTHORS Mai,M., Huang,H., Reed,C., Qian,C., Smith,J.S., Alderete,B., Jenkins,R., Smith,D.I. and Liu,W. TITLE Genomic organization and mutation analysis of p73 in oligodendrogliomas with chromosome 1 p-arm deletions JOURNAL Genomics 51 (3), 359-363 (1998) PUBMED 9721206 REFERENCE 8 (bases 1 to 4982) AUTHORS Nomoto,S., Haruki,N., Kondo,M., Konishi,H., Takahashi,T., Takahashi,T. and Takahashi,T. TITLE Search for mutations and examination of allelic expression imbalance of the p73 gene at 1p36.33 in human lung cancers JOURNAL Cancer Res. 58 (7), 1380-1383 (1998) PUBMED 9537234 REFERENCE 9 (bases 1 to 4982) AUTHORS Jost,C.A., Marin,M.C. and Kaelin,W.G. Jr. TITLE p73 is a simian [correction of human] p53-related protein that can induce apoptosis JOURNAL Nature 389 (6647), 191-194 (1997) PUBMED 9296498 REMARK Erratum:[Nature 1999 Jun 24;399(6738):817] REFERENCE 10 (bases 1 to 4982) AUTHORS Kaghad,M., Bonnet,H., Yang,A., Creancier,L., Biscan,J.C., Valent,A., Minty,A., Chalon,P., Lelias,J.M., Dumont,X., Ferrara,P., McKeon,F. and Caput,D. TITLE Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers JOURNAL Cell 90 (4), 809-819 (1997) PUBMED 9288759 REMARK GeneRIF: TP73 gene is imprinted, with monoallelic expression likely from the maternal allele. COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY040829.1, AL136528.11 and AI094238.1. On Feb 18, 2011 this sequence version replaced gi:187829051. Summary: This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011]. Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence and lacks an alternate coding exon compared to variant 1, that causes a frameshift. The resulting isoform (d, also known as deltaN p73 gamma) has a shorter and distinct N-terminus and a shorter and distinct C-terminus compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY040829.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025081, ERS025084 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## imprinted gene :: PMID: 9288759 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-605 AY040829.1 1-605 606-606 AL136528.11 47121-47121 c 607-2062 AY040829.1 607-2062 2063-4949 AL136528.11 33052-35938 c 4950-4982 AI094238.1 1-33 c FEATURES Location/Qualifiers source 1..4982 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" /chromosome="1" /map="1p36.3" gene 1..4982 /gene="TP73" /gene_synonym="P73" /note="tumor protein p73" /db_xref="GeneID:7161" /db_xref="HGNC:12003" /db_xref="MIM:601990" exon 1..273 /gene="TP73" /gene_synonym="P73" /inference="alignment:Splign:1.39.8" misc_feature 148..150 /gene="TP73" /gene_synonym="P73" /note="upstream in-frame stop codon" CDS 235..1515 /gene="TP73" /gene_synonym="P73" /note="isoform d is encoded by transcript variant 4; p53-related protein; p53-like transcription factor" /codon_start=1 /product="tumor protein p73 isoform d" /protein_id="NP_001119714.1" /db_xref="GI:187829052" /db_xref="CCDS:CCDS44051.1" /db_xref="GeneID:7161" /db_xref="HGNC:12003" /db_xref="MIM:601990" /translation="
MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPPRDAQQPWPRSASQRRDEQQPQRPVHGLGVPLHSATPLPRRPQPRQFFNRIGVSKLHRVFHLPRVTEHLPPAEPDH
" misc_feature 466..1005 /gene="TP73" /gene_synonym="P73" /note="P53 DNA-binding domain; Region: P53; cd08367" /db_xref="CDD:176262" misc_feature order(667..669,676..678,859..861,871..873) /gene="TP73" /gene_synonym="P73" /note="zinc binding site [ion binding]; other site" /db_xref="CDD:176262" misc_feature order(670..678,682..684) /gene="TP73" /gene_synonym="P73" /note="dimerization site [polypeptide binding]; other site" /db_xref="CDD:176262" misc_feature order(862..864,868..870,889..891,964..966,970..978, 985..987) /gene="TP73" /gene_synonym="P73" /note="DNA binding site [nucleotide binding]" /db_xref="CDD:176262" misc_feature 1123..1245 /gene="TP73" /gene_synonym="P73" /note="P53 tetramerisation motif; Region: P53_tetramer; pfam07710" /db_xref="CDD:149007" exon 274..516 /gene="TP73" /gene_synonym="P73" /inference="alignment:Splign:1.39.8" exon 517..703 /gene="TP73" /gene_synonym="P73" /inference="alignment:Splign:1.39.8" exon 704..819 /gene="TP73" /gene_synonym="P73" /inference="alignment:Splign:1.39.8" exon 820..929 /gene="TP73" /gene_synonym="P73" /inference="alignment:Splign:1.39.8" STS 851..1023 /gene="TP73" /gene_synonym="P73" /standard_name="MARC_17809-17810:1024936155:1" /db_xref="UniSTS:268408" exon 930..1072 /gene="TP73" /gene_synonym="P73" /inference="alignment:Splign:1.39.8" exon 1073..1161 /gene="TP73" /gene_synonym="P73" /inference="alignment:Splign:1.39.8" exon 1162..1283 /gene="TP73" /gene_synonym="P73" /inference="alignment:Splign:1.39.8" exon 1284..1422 /gene="TP73" /gene_synonym="P73" /inference="alignment:Splign:1.39.8" exon 1423..1516 /gene="TP73" /gene_synonym="P73" /inference="alignment:Splign:1.39.8" exon 1517..4971 /gene="TP73" /gene_synonym="P73" /inference="alignment:Splign:1.39.8" STS 3237..3428 /gene="TP73" /gene_synonym="P73" /standard_name="D1S1310" /db_xref="UniSTS:149507" STS 4698..4818 /gene="TP73" /gene_synonym="P73" /standard_name="SHGC-74137" /db_xref="UniSTS:76612" variation complement(4823) /gene="TP73" /gene_synonym="P73" /replace="c" /replace="g" /db_xref="dbSNP:1047928" polyA_signal 4950..4955 /gene="TP73" /gene_synonym="P73" polyA_site 4971 /gene="TP73" /gene_synonym="P73" ORIGIN
ggattcagccagttgacagaactaagggagatgggaaaagcgaaaatgccaacaaacggcccgcatgttccccagcatcctcggctcctgcctcactagctgcggagcctctcccgctcggtccacgctgccgggcggccacgaccgtgacccttcccctcgggccgcccagatccatgcctcgtcccacgggacaccagttccctggcgtgtgcagaccccccggcgcctaccatgctgtacgtcggtgaccccgcacggcacctcgccacggcccagttcaatctgctgagcagcaccatggaccagatgagcagccgcgcggcctcggccagcccctacaccccagagcacgccgccagcgtgcccacccactcgccctacgcacaacccagctccaccttcgacaccatgtcgccggcgcctgtcatcccctccaacaccgactaccccggaccccaccactttgaggtcactttccagcagtccagcacggccaagtcagccacctggacgtactccccgctcttgaagaaactctactgccagatcgccaagacatgccccatccagatcaaggtgtccaccccgccacccccaggcaccgccatccgggccatgcctgtttacaagaaagcggagcacgtgaccgacgtcgtgaaacgctgccccaaccacgagctcgggagggacttcaacgaaggacagtctgctccagccagccacctcatccgcgtggaaggcaataatctctcgcagtatgtggatgaccctgtcaccggcaggcagagcgtcgtggtgccctatgagccaccacaggtggggacggaattcaccaccatcctgtacaacttcatgtgtaacagcagctgtgtagggggcatgaaccggcggcccatcctcatcatcatcaccctggagatgcgggatgggcaggtgctgggccgccggtcctttgagggccgcatctgcgcctgtcctggccgcgaccgaaaagctgatgaggaccactaccgggagcagcaggccctgaacgagagctccgccaagaacggggccgccagcaagcgtgccttcaagcagagcccccctgccgtccccgcccttggtgccggtgtgaagaagcggcggcatggagacgaggacacgtactaccttcaggtgcgaggccgggagaactttgagatcctgatgaagctgaaagagagcctggagctgatggagttggtgccgcagccactggtggactcctatcggcagcagcagcagctcctacagaggccgccccgggatgctcaacaaccatggccacgcagtgccagccaacggcgagatgagcagcagccacagcgcccagtccatggtctcggggtcccactgcactccgccacccccctaccacgccgaccccagcctcgtcagttttttaacaggattggggtgtccaaactgcatcgagtatttcacctcccaagggttacagagcatttaccacctgcagaacctgaccattgaggacctgggggccctgaagatccccgagcagtaccgcatgaccatctggcggggcctgcaggacctgaagcagggccacgactacagcaccgcgcagcagctgctccgctctagcaacgcggccaccatctccatcggcggctcaggggaactgcagcgccagcgggtcatggaggccgtgcacttccgcgtgcgccacaccatcaccatccccaaccgcggcggcccaggcggcggccctgacgagtgggcggacttcggcttcgacctgcccgactgcaaggcccgcaagcagcccatcaaggaggagttcacggaggccgagatccactgagggcctcgcctggctgcagcctgcgccaccgcccagagacccaagctgcctcccctctccttcctgtgtgtccaaaactgcctcaggaggcaggaccttcgggctgtgcccggggaaaggcaaggtccggcccatccccaggcacctcacaggccccaggaaaggcccagccaccgaagccgcctgtggacagcctgagtcacctgcagaaccttctggagctgccctagtgctgggcttgtggggcgggggctggcccactctcagccctgccactgccccggcgtgctccatggcaggcgtgggtggggaccgcagcgtcggctccgacttccaggcttcatcctagagactgtcatctcccaaccaggcgaggtccttccaaaggaaaggatcctctttgctgatggactgccaaaaagtattttgcgacatcttttggttctggatagtagtgagcagccaagtgactgtgtctgaaacaccagtgtattttcagggaatgtccctaactgcgtcttgcccgcgccgggggctggggactctctctgctggacttgggactggcctctgcccccagcacgctgtattctgcaggaccgcctccttcctgcccctaacaacaaccacagtgttgctgaaattggagaaaactggggagggcgcaaccccccccaggcgcggggaagcatgtggtaccgcctcagccagtgcccctcagcctggccacagtcgcctctcctcggggacccctcagcagaaagggacagcctgtccttagaggactggaaattgtcaatatttgataaaatgatacccttttctacatggtgggtcagcttttttttttttttttttaactttctttctcagcattctctttggagttcaacctagcgcccatgagccaggctgaggaagctgagtgagaagccaggtgggcgggacttgttcccaggaaggccgggtggggaggaagcctagagggaaccccaggaagggcaaatccaggcaaatctgcaggaatgctctgccatgggagcagctcctcccttgccacggccaccttctctagcactgcaaggtccacagggcattgctttcctttctaggcggtggcagtcagggaacagactgaggtaggtgtaggggggtctaggccttcgtggagcaccccagggagttagtaggccccggggagacagagtctgcacaggccctttctggggccacctccatccacgaggagcagcctgagccttggtggccgaaccttgaccgtcccggagcacagcttcagggcagggaaccggagcccctggggggcctcacgggtgtgacgaggcccttcattgcaggcaggtgggccaatgggagccctcacccacgcaagccgagacaccacccagagtgcaggctgcctggccccttctggcacggccagctccacaccccctgcctagggtatgtgtggtcctaagggctaggagcttcccctactaacatctcccagaaaaagcagttaagcccctcagggcacagcaaggttagacacagcccccatccccagatcaggactccatcttgctaagtggcatcaccgtcaccagcctccccttatttaaaagcagcgactggtgttgccgcaggtacctggtctacgaagacgcaggcatccctctcccaccgtccacctccccgggggccgctgacagcacagtcgcctgggtgcacgcttgtgggggcagcaggaacggggctgtcggctctcaggggatctggctgcagccagggcgagggcctggcccttccttccagctccttccggctccttccagctgaagggcaggaagctctggccgcttagcttctagggttccatctccctagaaaggtgcccacgcccagggcatcagtcagtagcggcagcagcagcagactcggggctttcccagggtggcgcagccaccccagctgcatgtcacctcagctctccatcttattgccattttgtagatgaggaagctgagaccagaaaggctaagacccatgccccaggcaccacacccatctcttgggggctgggcacctgctacccgaggccacctcctgaagcccccactcttcccccatgttccacttcaggagccgcgggggcccatcctgacacccggggttcctcagcccagcgcagatgtgcttcagttccagagggcttgttgatttgtttcttaggtacgttacctgtccaccctgagtccagtgaggctgtcccaagagcccctgtagtgtgctcctgggaagggctgggggggctgggggggctgggagaggcccaggggcagctgtcactggaaccccagccagatgtccaaggaagccggccagaacacggagcagccagatggccccagctgcacctgtctagggagcccatgcagcctccttgcactggagaagcagctgtgaaagtagacagagttgagacttcgccgtggtcaggagaaaatgcaaattcccaggaacaagaatcctttaagtgatatgtttttataaaactaaacaaatcaacaaataaatcttgaaggcggatggttttcccagcagtgcaggggttggagggaggctgctggcactcctggggccaagggggacaggcagtggtcctgagtctgctcagagaggcaaggcagaaggagctcgccaggcaggtcagctcacatctgtccaagtcgctctggtcagaaacagcgactctcccccattcccccagcgttcccaccaggcctgggctgctgggaagcccttgctgtacccaggagcccgacccgcagtatcctggcacagagccacttgtcactcagaacagtcagtgtctccaacgcacaaacatccactcctctgttaccagttaaagcactttaatgctttaaggtgaaaacgaaatcccatccgtgtttttcgtgtaagatcgtgcttctccgagcagtattaatggacgccctccaatgacataacaactgtttttggtaatgtaatcttgggaaaatgtgttatttttttagctgtgtttcagtggggatttttgtttttgtaacataataaagtgtatgttccaatgaaaaaaaaaaaa
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ANNOTATIONS from NCBI Entrez Gene (20130726): GeneID:7161 -> Molecular function: GO:0002039 [p53 binding] evidence: IBA GeneID:7161 -> Molecular function: GO:0003682 [chromatin binding] evidence: IBA GeneID:7161 -> Molecular function: GO:0003684 [damaged DNA binding] evidence: IBA GeneID:7161 -> Molecular function: GO:0003690 [double-stranded DNA binding] evidence: IBA GeneID:7161 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IDA GeneID:7161 -> Molecular function: GO:0005515 [protein binding] evidence: IPI GeneID:7161 -> Molecular function: GO:0008134 [transcription factor binding] evidence: IPI GeneID:7161 -> Molecular function: GO:0019901 [protein kinase binding] evidence: IPI GeneID:7161 -> Molecular function: GO:0042802 [identical protein binding] evidence: IPI GeneID:7161 -> Molecular function: GO:0043565 [sequence-specific DNA binding] evidence: IEA GeneID:7161 -> Molecular function: GO:0044212 [transcription regulatory region DNA binding] evidence: IDA GeneID:7161 -> Molecular function: GO:0046872 [metal ion binding] evidence: IEA GeneID:7161 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IBA GeneID:7161 -> Biological process: GO:0000187 [activation of MAPK activity] evidence: IEA GeneID:7161 -> Biological process: GO:0001822 [kidney development] evidence: IEA GeneID:7161 -> Biological process: GO:0001836 [release of cytochrome c from mitochondria] evidence: IEA GeneID:7161 -> Biological process: GO:0006298 [mismatch repair] evidence: TAS GeneID:7161 -> Biological process: GO:0006351 [transcription, DNA-dependent] evidence: IEA GeneID:7161 -> Biological process: GO:0006954 [inflammatory response] evidence: IEA GeneID:7161 -> Biological process: GO:0006974 [response to DNA damage stimulus] evidence: IDA GeneID:7161 -> Biological process: GO:0006978 [DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator] evidence: IBA GeneID:7161 -> Biological process: GO:0007050 [cell cycle arrest] evidence: IEA GeneID:7161 -> Biological process: GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage] evidence: TAS GeneID:7161 -> Biological process: GO:0009791 [post-embryonic development] evidence: IEA GeneID:7161 -> Biological process: GO:0010165 [response to X-ray] evidence: IBA GeneID:7161 -> Biological process: GO:0010243 [response to organonitrogen compound] evidence: IEA GeneID:7161 -> Biological process: GO:0010332 [response to gamma radiation] evidence: IBA GeneID:7161 -> Biological process: GO:0021766 [hippocampus development] evidence: IEA GeneID:7161 -> Biological process: GO:0031571 [mitotic G1 DNA damage checkpoint] evidence: IBA GeneID:7161 -> Biological process: GO:0033326 [cerebrospinal fluid secretion] evidence: IEA GeneID:7161 -> Biological process: GO:0034644 [cellular response to UV] evidence: IBA GeneID:7161 -> Biological process: GO:0042771 [intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator] evidence: IBA GeneID:7161 -> Biological process: GO:0042771 [intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator] evidence: IDA GeneID:7161 -> Biological process: GO:0043065 [positive regulation of apoptotic process] evidence: IEA GeneID:7161 -> Biological process: GO:0043508 [negative regulation of JUN kinase activity] evidence: IBA GeneID:7161 -> Biological process: GO:0043524 [negative regulation of neuron apoptotic process] evidence: IBA GeneID:7161 -> Biological process: GO:0045665 [negative regulation of neuron differentiation] evidence: IEA GeneID:7161 -> Biological process: GO:0045793 [positive regulation of cell size] evidence: IEA GeneID:7161 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: IDA GeneID:7161 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IDA GeneID:7161 -> Biological process: GO:0048546 [digestive tract morphogenesis] evidence: IEA GeneID:7161 -> Biological process: GO:0048666 [neuron development] evidence: IEA GeneID:7161 -> Biological process: GO:0048714 [positive regulation of oligodendrocyte differentiation] evidence: IEA GeneID:7161 -> Biological process: GO:0051262 [protein tetramerization] evidence: IEA GeneID:7161 -> Cellular component: GO:0000785 [chromatin] evidence: IBA GeneID:7161 -> Cellular component: GO:0005634 [nucleus] evidence: IDA GeneID:7161 -> Cellular component: GO:0005667 [transcription factor complex] evidence: IBA GeneID:7161 -> Cellular component: GO:0005829 [cytosol] evidence: IBA
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