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2024-04-25 07:31:01, GGRNA : RefSeq release 60 (20130726)
LOCUS NM_001126112 2588 bp mRNA linear PRI 15-JUL-2013
DEFINITION Homo sapiens tumor protein p53 (TP53), transcript variant 2, mRNA.
ACCESSION NM_001126112
VERSION NM_001126112.2 GI:371502115
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2588)
AUTHORS Marcel,V., Tran,P.L., Sagne,C., Martel-Planche,G., Vaslin,L.,
Teulade-Fichou,M.P., Hall,J., Mergny,J.L., Hainaut,P. and Van
Dyck,E.
TITLE G-quadruplex structures in TP53 intron 3: role in alternative
splicing and in production of p53 mRNA isoforms
JOURNAL Carcinogenesis 32 (3), 271-278 (2011)
PUBMED 21112961
REFERENCE 2 (bases 1 to 2588)
AUTHORS Marcel,V., Perrier,S., Aoubala,M., Ageorges,S., Groves,M.J.,
Diot,A., Fernandes,K., Tauro,S. and Bourdon,J.C.
TITLE Delta160p53 is a novel N-terminal p53 isoform encoded by
Delta133p53 transcript
JOURNAL FEBS Lett. 584 (21), 4463-4468 (2010)
PUBMED 20937277
REMARK GeneRIF: Delta133p53 transcript generates two different p53
isoforms, Delta133p53 and Delta160p53
REFERENCE 3 (bases 1 to 2588)
AUTHORS Anczukow,O., Ware,M.D., Buisson,M., Zetoune,A.B.,
Stoppa-Lyonnet,D., Sinilnikova,O.M. and Mazoyer,S.
TITLE Does the nonsense-mediated mRNA decay mechanism prevent the
synthesis of truncated BRCA1, CHK2, and p53 proteins?
JOURNAL Hum. Mutat. 29 (1), 65-73 (2008)
PUBMED 17694537
REMARK GeneRIF: the p53 protein encoded by the 770delT allele is as
abundant as the wild-type protein, as removal of the C-terminal p53
domain leads to a stabilized mutant protein, whose abundance is
markedly increased when NMD is inhibited.
REFERENCE 4 (bases 1 to 2588)
AUTHORS Bourdon,J.C.
TITLE p53 Family isoforms
JOURNAL Curr Pharm Biotechnol 8 (6), 332-336 (2007)
PUBMED 18289041
REMARK Review article
REFERENCE 5 (bases 1 to 2588)
AUTHORS Candeias,M.M., Powell,D.J., Roubalova,E., Apcher,S., Bourougaa,K.,
Vojtesek,B., Bruzzoni-Giovanelli,H. and Fahraeus,R.
TITLE Expression of p53 and p53/47 are controlled by alternative
mechanisms of messenger RNA translation initiation
JOURNAL Oncogene 25 (52), 6936-6947 (2006)
PUBMED 16983332
REMARK GeneRIF: harbouring alternative translation initiation sites, the
p53 mRNA gives rise to different levels of the p53 isoforms which
help to orchestrate the cell biological outcome of p53 activation
REFERENCE 6 (bases 1 to 2588)
AUTHORS Lamb,P. and Crawford,L.
TITLE Characterization of the human p53 gene
JOURNAL Mol. Cell. Biol. 6 (5), 1379-1385 (1986)
PUBMED 2946935
REFERENCE 7 (bases 1 to 2588)
AUTHORS Isobe,M., Emanuel,B.S., Givol,D., Oren,M. and Croce,C.M.
TITLE Localization of gene for human p53 tumour antigen to band 17p13
JOURNAL Nature 320 (6057), 84-85 (1986)
PUBMED 3456488
REFERENCE 8 (bases 1 to 2588)
AUTHORS Benchimol,S., Lamb,P., Crawford,L.V., Sheer,D., Shows,T.B.,
Bruns,G.A. and Peacock,J.
TITLE Transformation associated p53 protein is encoded by a gene on human
chromosome 17
JOURNAL Somat. Cell Mol. Genet. 11 (5), 505-510 (1985)
PUBMED 2994241
REFERENCE 9 (bases 1 to 2588)
AUTHORS Harlow,E., Williamson,N.M., Ralston,R., Helfman,D.M. and Adams,T.E.
TITLE Molecular cloning and in vitro expression of a cDNA clone for human
cellular tumor antigen p53
JOURNAL Mol. Cell. Biol. 5 (7), 1601-1610 (1985)
PUBMED 3894933
REFERENCE 10 (bases 1 to 2588)
AUTHORS Zakut-Houri,R., Bienz-Tadmor,B., Givol,D. and Oren,M.
TITLE Human p53 cellular tumor antigen: cDNA sequence and expression in
COS cells
JOURNAL EMBO J. 4 (5), 1251-1255 (1985)
PUBMED 4006916
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA453049.1, AB082923.1,
X02469.1, AK223026.1 and DQ186650.1.
This sequence is a reference standard in the RefSeqGene project.
On Jan 7, 2012 this sequence version replaced gi:187830776.
Summary: This gene encodes a tumor suppressor protein containing
transcriptional activation, DNA binding, and oligomerization
domains. The encoded protein responds to diverse cellular stresses
to regulate expression of target genes, thereby inducing cell cycle
arrest, apoptosis, senescence, DNA repair, or changes in
metabolism. Mutations in this gene are associated with a variety of
human cancers, including hereditary cancers such as Li-Fraumeni
syndrome. Alternative splicing of this gene and the use of
alternate promoters result in multiple transcript variants and
isoforms. Additional isoforms have also been shown to result from
the use of alternate translation initiation codons (PMIDs:
12032546, 20937277). [provided by RefSeq, Feb 2013].
Transcript Variant: This variant (2) uses an alternate splice site
in the 5' UTR, compared to variant 1. This variant can initiate
translation from two in-frame AUG start codons. The isoform
represented in this variant (a, also known as p53alpha) results
from translation initiation at the upstream start codon. Both
variants 1 and 2 encode isoform a, which is the longest isoform.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: AB082923.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
ERS025081, ERS025082 [ECO:0000350]
##Evidence-Data-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-136 DA453049.1 1-136
137-413 AB082923.1 1-277
414-1381 X02469.1 350-1317
1382-2569 AK223026.1 478-1665
2570-2588 DQ186650.1 2257-2275
FEATURES Location/Qualifiers
source 1..2588
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17p13.1"
gene 1..2588
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/note="tumor protein p53"
/db_xref="GeneID:7157"
/db_xref="HGNC:11998"
/db_xref="MIM:191170"
exon 1..174
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/inference="alignment:Splign:1.39.8"
variation 92
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/db_xref="dbSNP:17884410"
misc_feature 95..97
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/note="upstream in-frame stop codon"
exon 175..273
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/inference="alignment:Splign:1.39.8"
CDS 200..1381
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/note="isoform a is encoded by transcript variant 2;
cellular tumor antigen p53; phosphoprotein p53;
transformation-related protein 53; p53 tumor suppressor;
antigen NY-CO-13"
/codon_start=1
/product="cellular tumor antigen p53 isoform a"
/protein_id="NP_001119584.1"
/db_xref="GI:187830777"
/db_xref="CCDS:CCDS11118.1"
/db_xref="GeneID:7157"
/db_xref="HGNC:11998"
/db_xref="MIM:191170"
/translation="
MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD
"
misc_feature 200..448
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Interaction with HRMT1L2"
misc_feature 200..331
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Transcription activation (acidic)"
misc_feature 212..286
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/note="P53 transactivation motif; Region: P53_TAD;
pfam08563"
/db_xref="CDD:149567"
misc_feature 224..226
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by HIPK4; propagated from
UniProtKB/Swiss-Prot (P04637.4); phosphorylation site"
misc_feature 242..244
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by CDK5, PRPK, AMPK, NUAK1 and ATM;
propagated from UniProtKB/Swiss-Prot (P04637.4);
phosphorylation site"
misc_feature 248..274
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: TADI"
misc_feature 251..253
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine, by CK1, VRK1 and VRK2; propagated
from UniProtKB/Swiss-Prot (P04637.4); phosphorylation
site"
misc_feature 257..259
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by CHEK2, CK1 and PLK3; propagated
from UniProtKB/Swiss-Prot (P04637.4); phosphorylation
site"
misc_feature 296..298
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by CDK5 and CDK7; propagated from
UniProtKB/Swiss-Prot (P04637.4); phosphorylation site"
misc_feature 308..310
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by MAPKAPK5; propagated from
UniProtKB/Swiss-Prot (P04637.4); phosphorylation site"
misc_feature 317..319
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/note="delta40p53alpha; Region: alternative start codon"
misc_feature 335..337
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by CDK5, DYRK2, HIPK2 and PKC/PRKCG;
propagated from UniProtKB/Swiss-Prot (P04637.4);
phosphorylation site"
misc_feature 341..367
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: TADII"
misc_feature 362..364
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine, by TAF1 and GRK5; propagated from
UniProtKB/Swiss-Prot (P04637.4); phosphorylation site"
misc_feature 395..529
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Interaction with WWOX"
misc_feature 497..1309
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Interaction with HIPK1 (By similarity)"
misc_feature 524..1063
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/note="P53 DNA-binding domain; Region: P53; cd08367"
/db_xref="CDD:176262"
misc_feature 536..907
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Required for interaction with FBXO42"
misc_feature 545..1075
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/inference="non-experimental evidence, no additional
details recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Interaction with AXIN1 (By similarity)"
misc_feature 557..559
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine, by KAT6A; propagated from
UniProtKB/Swiss-Prot (P04637.4); acetylation site"
misc_feature 557..559
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="Interaction with DNA; propagated from
UniProtKB/Swiss-Prot (P04637.4); other site"
misc_feature order(725..727,734..736,911..913,923..925)
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/note="zinc binding site [ion binding]; other site"
/db_xref="CDD:176262"
misc_feature order(728..736,740..742)
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/note="dimerization site [polypeptide binding]; other
site"
/db_xref="CDD:176262"
misc_feature 746..748
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by AURKB; propagated from
UniProtKB/Swiss-Prot (P04637.4); phosphorylation site"
misc_feature order(914..916,920..922,941..943,1016..1018,1022..1030,
1037..1039)
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/note="DNA binding site [nucleotide binding]"
/db_xref="CDD:176262"
misc_feature 920..943
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Interacts with the 53BP2 SH3 domain"
misc_feature 965..1081
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Interaction with E4F1"
misc_feature 1004..1006
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by AURKB; propagated from
UniProtKB/Swiss-Prot (P04637.4); phosphorylation site"
misc_feature 1016..1039
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Interaction with DNA"
misc_feature 1049..1051
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine, by AURKB; propagated from
UniProtKB/Swiss-Prot (P04637.4); phosphorylation site"
misc_feature 1097..1378
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Interaction with CARM1"
misc_feature 1112..1162
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Bipartite nuclear localization signal"
misc_feature 1112..1114
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine; propagated from
UniProtKB/Swiss-Prot (P04637.4); acetylation site"
misc_feature 1142..1144
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by AURKA, CDK1 and CDK2; propagated
from UniProtKB/Swiss-Prot (P04637.4); phosphorylation
site"
misc_feature 1154..1279
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Interaction with HIPK2"
misc_feature 1154..1276
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/note="P53 tetramerisation motif; Region: P53_tetramer;
pfam07710"
/db_xref="CDD:149007"
misc_feature 1172..1267
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Oligomerization"
misc_feature 1214..1249
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Nuclear export signal"
misc_feature 1274..1288
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Interaction with USP7"
misc_feature 1301..1360
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: Basic (repression of DNA-binding)"
misc_feature 1307..1315
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (P04637.4);
Region: [KR]-[STA]-K motif"
misc_feature 1307..1309
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="N6,N6-dimethyllysine, alternate; N6-methyllysine,
by SMYD2, alternate; propagated from UniProtKB/Swiss-Prot
(P04637.4); methylation site"
misc_feature 1313..1315
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-methyllysine, by SETD7; propagated from
UniProtKB/Swiss-Prot (P04637.4); methylation site"
misc_feature 1316..1318
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine, alternate; propagated from
UniProtKB/Swiss-Prot (P04637.4); acetylation site"
misc_feature 1316..1318
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="N6,N6-dimethyllysine, by EHMT1 and EHMT2,
alternate; propagated from UniProtKB/Swiss-Prot
(P04637.4); methylation site"
misc_feature 1340..1342
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine; propagated from
UniProtKB/Swiss-Prot (P04637.4); acetylation site"
misc_feature 1343..1345
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="N6-acetyllysine, by KAT6A, alternate; propagated
from UniProtKB/Swiss-Prot (P04637.4); acetylation site"
misc_feature 1343..1345
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="N6,N6-dimethyllysine, alternate; N6-methyllysine,
by SETD8, alternate; propagated from UniProtKB/Swiss-Prot
(P04637.4); methylation site"
misc_feature 1373..1375
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine, by CK2, CDK2 and NUAK1; propagated
from UniProtKB/Swiss-Prot (P04637.4); phosphorylation
site"
variation 262
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="c"
/replace="t"
/db_xref="dbSNP:1800369"
exon 274..295
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/inference="alignment:Splign:1.39.8"
exon 296..574
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/inference="alignment:Splign:1.39.8"
variation 301
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="c"
/db_xref="dbSNP:11575998"
STS 302..500
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/standard_name="GDB:177814"
/db_xref="UniSTS:154969"
variation 307
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/db_xref="dbSNP:1800370"
STS 316..574
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/standard_name="GDB:177797"
/db_xref="UniSTS:154963"
variation 338
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="c"
/replace="t"
/db_xref="dbSNP:1800371"
variation 528
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:11540654"
exon 575..758
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/inference="alignment:Splign:1.39.8"
variation 658
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="c"
/replace="t"
/db_xref="dbSNP:72661116"
STS 677..751
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/standard_name="PMC340938P3"
/db_xref="UniSTS:273171"
variation 749
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/db_xref="dbSNP:72661117"
exon 759..871
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/inference="alignment:Splign:1.39.8"
variation 838
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:1800372"
variation 848
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/db_xref="dbSNP:35163653"
variation 865
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:72661118"
exon 872..981
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/inference="alignment:Splign:1.39.8"
STS 952..1150
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/standard_name="PMC310707P2"
/db_xref="UniSTS:272633"
STS 956..1030
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/standard_name="GDB:190076"
/db_xref="UniSTS:155620"
exon 982..1118
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/inference="alignment:Splign:1.39.8"
variation 986
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/db_xref="dbSNP:72661119"
variation 1102
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/db_xref="dbSNP:72661120"
exon 1119..1192
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/inference="alignment:Splign:1.39.8"
variation 1192
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/db_xref="dbSNP:11575996"
exon 1193..1299
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/inference="alignment:Splign:1.39.8"
variation 1214
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/db_xref="dbSNP:17882252"
variation 1278
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="c"
/replace="g"
/db_xref="dbSNP:35993958"
variation 1295
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="g"
/replace="t"
/db_xref="dbSNP:17881470"
exon 1300..2588
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/inference="alignment:Splign:1.39.8"
variation 1418
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="t"
/db_xref="dbSNP:1042526"
STS 1451..1567
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/standard_name="D17S1678"
/db_xref="UniSTS:82485"
variation 1486
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="c"
/replace="t"
/db_xref="dbSNP:35919705"
variation 1695
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/db_xref="dbSNP:34486624"
variation 1709
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/db_xref="dbSNP:17881366"
variation 1872
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/db_xref="dbSNP:916131"
variation 1895
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="c"
/replace="t"
/db_xref="dbSNP:916132"
STS 1908..2054
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/standard_name="D17S1506E"
/db_xref="UniSTS:151711"
variation 1915..1916
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="c"
/replace="t"
/db_xref="dbSNP:1811095"
variation 1951
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace=""
/replace="gt"
/db_xref="dbSNP:17886358"
variation 1994
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="c"
/db_xref="dbSNP:17879353"
variation 2015..2016
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/db_xref="dbSNP:1794291"
variation 2015
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="c"
/replace="g"
/db_xref="dbSNP:1042535"
variation 2135
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="c"
/replace="t"
/db_xref="dbSNP:199729221"
variation 2207
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/db_xref="dbSNP:17884306"
variation 2236
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="c"
/replace="t"
/db_xref="dbSNP:17884586"
variation 2267
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="g"
/db_xref="dbSNP:35659787"
variation 2437..2438
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="c"
/replace="g"
/db_xref="dbSNP:1794292"
STS 2443..2519
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/standard_name="WI-20715"
/db_xref="UniSTS:59997"
polyA_signal 2552..2557
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
variation 2556
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/replace="a"
/replace="c"
/db_xref="dbSNP:78378222"
polyA_site 2569
/gene="TP53"
/gene_synonym="BCC7; LFS1; P53; TRP53"
/note="The 3' most polyA site has not been determined."
ORIGIN
gatgggattggggttttcccctcccatgtgctcaagactggcgctaaaagttttgagcttctcaaaagtctagagccaccgtccagggagcaggtagctgctgggctccggggacactttgcgttcgggctgggagcgtgctttccacgacggtgacacgcttccctggattggccagactgccttccgggtcactgccatggaggagccgcagtcagatcctagcgtcgagccccctctgagtcaggaaacattttcagacctatggaaactacttcctgaaaacaacgttctgtcccccttgccgtcccaagcaatggatgatttgatgctgtccccggacgatattgaacaatggttcactgaagacccaggtccagatgaagctcccagaatgccagaggctgctccccccgtggcccctgcaccagcagctcctacaccggcggcccctgcaccagccccctcctggcccctgtcatcttctgtcccttcccagaaaacctaccagggcagctacggtttccgtctgggcttcttgcattctgggacagccaagtctgtgacttgcacgtactcccctgccctcaacaagatgttttgccaactggccaagacctgccctgtgcagctgtgggttgattccacacccccgcccggcacccgcgtccgcgccatggccatctacaagcagtcacagcacatgacggaggttgtgaggcgctgcccccaccatgagcgctgctcagatagcgatggtctggcccctcctcagcatcttatccgagtggaaggaaatttgcgtgtggagtatttggatgacagaaacacttttcgacatagtgtggtggtgccctatgagccgcctgaggttggctctgactgtaccaccatccactacaactacatgtgtaacagttcctgcatgggcggcatgaaccggaggcccatcctcaccatcatcacactggaagactccagtggtaatctactgggacggaacagctttgaggtgcgtgtttgtgcctgtcctgggagagaccggcgcacagaggaagagaatctccgcaagaaaggggagcctcaccacgagctgcccccagggagcactaagcgagcactgcccaacaacaccagctcctctccccagccaaagaagaaaccactggatggagaatatttcacccttcagatccgtgggcgtgagcgcttcgagatgttccgagagctgaatgaggccttggaactcaaggatgcccaggctgggaaggagccaggggggagcagggctcactccagccacctgaagtccaaaaagggtcagtctacctcccgccataaaaaactcatgttcaagacagaagggcctgactcagactgacattctccacttcttgttccccactgacagcctcccacccccatctctccctcccctgccattttgggttttgggtctttgaacccttgcttgcaataggtgtgcgtcagaagcacccaggacttccatttgctttgtcccggggctccactgaacaagttggcctgcactggtgttttgttgtggggaggaggatggggagtaggacataccagcttagattttaaggtttttactgtgagggatgtttgggagatgtaagaaatgttcttgcagttaagggttagtttacaatcagccacattctaggtaggggcccacttcaccgtactaaccagggaagctgtccctcactgttgaattttctctaacttcaaggcccatatctgtgaaatgctggcatttgcacctacctcacagagtgcattgtgagggttaatgaaataatgtacatctggccttgaaaccaccttttattacatggggtctagaacttgacccccttgagggtgcttgttccctctccctgttggtcggtgggttggtagtttctacagttgggcagctggttaggtagagggagttgtcaagtctctgctggcccagccaaaccctgtctgacaacctcttggtgaaccttagtacctaaaaggaaatctcaccccatcccacaccctggaggatttcatctcttgtatatgatgatctggatccaccaagacttgttttatgctcagggtcaatttcttttttcttttttttttttttttttctttttctttgagactgggtctcgctttgttgcccaggctggagtggagtggcgtgatcttggcttactgcagcctttgcctccccggctcgagcagtcctgcctcagcctccggagtagctgggaccacaggttcatgccaccatggccagccaacttttgcatgttttgtagagatggggtctcacagtgttgcccaggctggtctcaaactcctgggctcaggcgatccacctgtctcagcctcccagagtgctgggattacaattgtgagccaccacgtccagctggaagggtcaacatcttttacattctgcaagcacatctgcattttcaccccacccttcccctccttctccctttttatatcccatttttatatcgatctcttattttacaataaaactttgctgccacctgtgtgtctgaggggtg
//
ANNOTATIONS from NCBI Entrez Gene (20130726):
GeneID:7157 -> Molecular function: GO:0001077 [RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription] evidence: IEA
GeneID:7157 -> Molecular function: GO:0001085 [RNA polymerase II transcription factor binding] evidence: IPI
GeneID:7157 -> Molecular function: GO:0001228 [RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription] evidence: IDA
GeneID:7157 -> Molecular function: GO:0002020 [protease binding] evidence: IPI
GeneID:7157 -> Molecular function: GO:0002039 [p53 binding] evidence: IBA
GeneID:7157 -> Molecular function: GO:0003677 [DNA binding] evidence: IMP
GeneID:7157 -> Molecular function: GO:0003682 [chromatin binding] evidence: IDA
GeneID:7157 -> Molecular function: GO:0003684 [damaged DNA binding] evidence: IBA
GeneID:7157 -> Molecular function: GO:0003700 [sequence-specific DNA binding transcription factor activity] evidence: IDA
GeneID:7157 -> Molecular function: GO:0005507 [copper ion binding] evidence: IDA
GeneID:7157 -> Molecular function: GO:0005515 [protein binding] evidence: IPI
GeneID:7157 -> Molecular function: GO:0005524 [ATP binding] evidence: IDA
GeneID:7157 -> Molecular function: GO:0008134 [transcription factor binding] evidence: IPI
GeneID:7157 -> Molecular function: GO:0008270 [zinc ion binding] evidence: TAS
GeneID:7157 -> Molecular function: GO:0019899 [enzyme binding] evidence: IPI
GeneID:7157 -> Molecular function: GO:0019901 [protein kinase binding] evidence: IPI
GeneID:7157 -> Molecular function: GO:0030971 [receptor tyrosine kinase binding] evidence: IPI
GeneID:7157 -> Molecular function: GO:0031625 [ubiquitin protein ligase binding] evidence: IPI
GeneID:7157 -> Molecular function: GO:0035033 [histone deacetylase regulator activity] evidence: IEA
GeneID:7157 -> Molecular function: GO:0035035 [histone acetyltransferase binding] evidence: IPI
GeneID:7157 -> Molecular function: GO:0042802 [identical protein binding] evidence: IPI
GeneID:7157 -> Molecular function: GO:0044212 [transcription regulatory region DNA binding] evidence: IDA
GeneID:7157 -> Molecular function: GO:0046982 [protein heterodimerization activity] evidence: IPI
GeneID:7157 -> Molecular function: GO:0047485 [protein N-terminus binding] evidence: IPI
GeneID:7157 -> Molecular function: GO:0051087 [chaperone binding] evidence: IPI
GeneID:7157 -> Molecular function: GO:0051721 [protein phosphatase 2A binding] evidence: IPI
GeneID:7157 -> Molecular function: GO:0097371 [MDM2/MDM4 family protein binding] evidence: IEA
GeneID:7157 -> Biological process: GO:0000060 [protein import into nucleus, translocation] evidence: IEA
GeneID:7157 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IBA
GeneID:7157 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:7157 -> Biological process: GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] evidence: ISS
GeneID:7157 -> Biological process: GO:0000733 [DNA strand renaturation] evidence: IDA
GeneID:7157 -> Biological process: GO:0001701 [in utero embryonic development] evidence: IEA
GeneID:7157 -> Biological process: GO:0001756 [somitogenesis] evidence: IEA
GeneID:7157 -> Biological process: GO:0001836 [release of cytochrome c from mitochondria] evidence: IEA
GeneID:7157 -> Biological process: GO:0002309 [T cell proliferation involved in immune response] evidence: IEA
GeneID:7157 -> Biological process: GO:0002326 [B cell lineage commitment] evidence: IEA
GeneID:7157 -> Biological process: GO:0002360 [T cell lineage commitment] evidence: IEA
GeneID:7157 -> Biological process: GO:0002931 [response to ischemia] evidence: IEA
GeneID:7157 -> Biological process: GO:0006284 [base-excision repair] evidence: TAS
GeneID:7157 -> Biological process: GO:0006289 [nucleotide-excision repair] evidence: IMP
GeneID:7157 -> Biological process: GO:0006302 [double-strand break repair] evidence: IEA
GeneID:7157 -> Biological process: GO:0006355 [regulation of transcription, DNA-dependent] evidence: IDA
GeneID:7157 -> Biological process: GO:0006461 [protein complex assembly] evidence: IDA
GeneID:7157 -> Biological process: GO:0006917 [induction of apoptosis] evidence: IEA
GeneID:7157 -> Biological process: GO:0006974 [response to DNA damage stimulus] evidence: IDA
GeneID:7157 -> Biological process: GO:0006977 [DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest] evidence: TAS
GeneID:7157 -> Biological process: GO:0006978 [DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator] evidence: IMP
GeneID:7157 -> Biological process: GO:0006983 [ER overload response] evidence: IDA
GeneID:7157 -> Biological process: GO:0007050 [cell cycle arrest] evidence: IDA
GeneID:7157 -> Biological process: GO:0007050 [cell cycle arrest] evidence: IMP
GeneID:7157 -> Biological process: GO:0007179 [transforming growth factor beta receptor signaling pathway] evidence: IEA
GeneID:7157 -> Biological process: GO:0007265 [Ras protein signal transduction] evidence: IEP
GeneID:7157 -> Biological process: GO:0007275 [multicellular organismal development] evidence: IMP
GeneID:7157 -> Biological process: GO:0007369 [gastrulation] evidence: IEA
GeneID:7157 -> Biological process: GO:0007406 [negative regulation of neuroblast proliferation] evidence: IEA
GeneID:7157 -> Biological process: GO:0007417 [central nervous system development] evidence: IEA
GeneID:7157 -> Biological process: GO:0007569 [cell aging] evidence: IMP
GeneID:7157 -> Biological process: GO:0007596 [blood coagulation] evidence: TAS
GeneID:7157 -> Biological process: GO:0008104 [protein localization] evidence: IDA
GeneID:7157 -> Biological process: GO:0008156 [negative regulation of DNA replication] evidence: IEA
GeneID:7157 -> Biological process: GO:0008283 [cell proliferation] evidence: TAS
GeneID:7157 -> Biological process: GO:0008285 [negative regulation of cell proliferation] evidence: ISS
GeneID:7157 -> Biological process: GO:0008340 [determination of adult lifespan] evidence: ISS
GeneID:7157 -> Biological process: GO:0009303 [rRNA transcription] evidence: IEA
GeneID:7157 -> Biological process: GO:0009651 [response to salt stress] evidence: IEA
GeneID:7157 -> Biological process: GO:0010165 [response to X-ray] evidence: IBA
GeneID:7157 -> Biological process: GO:0010332 [response to gamma radiation] evidence: IMP
GeneID:7157 -> Biological process: GO:0010666 [positive regulation of cardiac muscle cell apoptotic process] evidence: IEA
GeneID:7157 -> Biological process: GO:0019048 [modulation by virus of host morphology or physiology] evidence: IEA
GeneID:7157 -> Biological process: GO:0030154 [cell differentiation] evidence: TAS
GeneID:7157 -> Biological process: GO:0030308 [negative regulation of cell growth] evidence: IMP
GeneID:7157 -> Biological process: GO:0030330 [DNA damage response, signal transduction by p53 class mediator] evidence: IDA
GeneID:7157 -> Biological process: GO:0030330 [DNA damage response, signal transduction by p53 class mediator] evidence: IMP
GeneID:7157 -> Biological process: GO:0030512 [negative regulation of transforming growth factor beta receptor signaling pathway] evidence: IEA
GeneID:7157 -> Biological process: GO:0031065 [positive regulation of histone deacetylation] evidence: IBA
GeneID:7157 -> Biological process: GO:0031497 [chromatin assembly] evidence: IDA
GeneID:7157 -> Biological process: GO:0031571 [mitotic G1 DNA damage checkpoint] evidence: IMP
GeneID:7157 -> Biological process: GO:0032461 [positive regulation of protein oligomerization] evidence: IDA
GeneID:7157 -> Biological process: GO:0033077 [T cell differentiation in thymus] evidence: IEA
GeneID:7157 -> Biological process: GO:0034103 [regulation of tissue remodeling] evidence: IEA
GeneID:7157 -> Biological process: GO:0034613 [cellular protein localization] evidence: IDA
GeneID:7157 -> Biological process: GO:0034644 [cellular response to UV] evidence: IBA
GeneID:7157 -> Biological process: GO:0035264 [multicellular organism growth] evidence: IEA
GeneID:7157 -> Biological process: GO:0035690 [cellular response to drug] evidence: IEP
GeneID:7157 -> Biological process: GO:0042149 [cellular response to glucose starvation] evidence: IDA
GeneID:7157 -> Biological process: GO:0042771 [intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator] evidence: IDA
GeneID:7157 -> Biological process: GO:0042981 [regulation of apoptotic process] evidence: IDA
GeneID:7157 -> Biological process: GO:0043065 [positive regulation of apoptotic process] evidence: IDA
GeneID:7157 -> Biological process: GO:0043066 [negative regulation of apoptotic process] evidence: IDA
GeneID:7157 -> Biological process: GO:0043066 [negative regulation of apoptotic process] evidence: IEA
GeneID:7157 -> Biological process: GO:0043525 [positive regulation of neuron apoptotic process] evidence: IBA
GeneID:7157 -> Biological process: GO:0045892 [negative regulation of transcription, DNA-dependent] evidence: ISS
GeneID:7157 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: IDA
GeneID:7157 -> Biological process: GO:0045893 [positive regulation of transcription, DNA-dependent] evidence: IMP
GeneID:7157 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IDA
GeneID:7157 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IGI
GeneID:7157 -> Biological process: GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] evidence: IMP
GeneID:7157 -> Biological process: GO:0046677 [response to antibiotic] evidence: IEP
GeneID:7157 -> Biological process: GO:0046902 [regulation of mitochondrial membrane permeability] evidence: TAS
GeneID:7157 -> Biological process: GO:0048147 [negative regulation of fibroblast proliferation] evidence: IMP
GeneID:7157 -> Biological process: GO:0050731 [positive regulation of peptidyl-tyrosine phosphorylation] evidence: ISS
GeneID:7157 -> Biological process: GO:0051097 [negative regulation of helicase activity] evidence: TAS
GeneID:7157 -> Biological process: GO:0051262 [protein tetramerization] evidence: TAS
GeneID:7157 -> Biological process: GO:0051402 [neuron apoptotic process] evidence: IEA
GeneID:7157 -> Biological process: GO:0070245 [positive regulation of thymocyte apoptotic process] evidence: ISS
GeneID:7157 -> Biological process: GO:0071158 [positive regulation of cell cycle arrest] evidence: IMP
GeneID:7157 -> Biological process: GO:0071456 [cellular response to hypoxia] evidence: IEP
GeneID:7157 -> Biological process: GO:0071479 [cellular response to ionizing radiation] evidence: IMP
GeneID:7157 -> Biological process: GO:0071850 [mitotic cell cycle arrest] evidence: IEA
GeneID:7157 -> Biological process: GO:0072332 [intrinsic apoptotic signaling pathway by p53 class mediator] evidence: IMP
GeneID:7157 -> Biological process: GO:0090200 [positive regulation of release of cytochrome c from mitochondria] evidence: IDA
GeneID:7157 -> Biological process: GO:0090343 [positive regulation of cell aging] evidence: IEA
GeneID:7157 -> Biological process: GO:0090399 [replicative senescence] evidence: IMP
GeneID:7157 -> Biological process: GO:0090403 [oxidative stress-induced premature senescence] evidence: IMP
GeneID:7157 -> Biological process: GO:0097193 [intrinsic apoptotic signaling pathway] evidence: TAS
GeneID:7157 -> Biological process: GO:0097252 [oligodendrocyte apoptotic process] evidence: IDA
GeneID:7157 -> Biological process: GO:1901525 [negative regulation of macromitophagy] evidence: IEA
GeneID:7157 -> Biological process: GO:2000378 [negative regulation of reactive oxygen species metabolic process] evidence: IEA
GeneID:7157 -> Biological process: GO:2000379 [positive regulation of reactive oxygen species metabolic process] evidence: IMP
GeneID:7157 -> Biological process: GO:2001244 [positive regulation of intrinsic apoptotic signaling pathway] evidence: IMP
GeneID:7157 -> Cellular component: GO:0000785 [chromatin] evidence: IBA
GeneID:7157 -> Cellular component: GO:0000790 [nuclear chromatin] evidence: IDA
GeneID:7157 -> Cellular component: GO:0005634 [nucleus] evidence: IDA
GeneID:7157 -> Cellular component: GO:0005654 [nucleoplasm] evidence: IDA
GeneID:7157 -> Cellular component: GO:0005654 [nucleoplasm] evidence: TAS
GeneID:7157 -> Cellular component: GO:0005657 [replication fork] evidence: IBA
GeneID:7157 -> Cellular component: GO:0005669 [transcription factor TFIID complex] evidence: IDA
GeneID:7157 -> Cellular component: GO:0005730 [nucleolus] evidence: IDA
GeneID:7157 -> Cellular component: GO:0005737 [cytoplasm] evidence: IDA
GeneID:7157 -> Cellular component: GO:0005739 [mitochondrion] evidence: IDA
GeneID:7157 -> Cellular component: GO:0005759 [mitochondrial matrix] evidence: IEA
GeneID:7157 -> Cellular component: GO:0005783 [endoplasmic reticulum] evidence: IEA
GeneID:7157 -> Cellular component: GO:0005829 [cytosol] evidence: IBA
GeneID:7157 -> Cellular component: GO:0005829 [cytosol] evidence: IDA
GeneID:7157 -> Cellular component: GO:0016363 [nuclear matrix] evidence: IDA
GeneID:7157 -> Cellular component: GO:0016604 [nuclear body] evidence: IDA
GeneID:7157 -> Cellular component: GO:0016605 [PML body] evidence: IDA
GeneID:7157 -> Cellular component: GO:0043234 [protein complex] evidence: IDA
by
@meso_cacase at
DBCLS
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